locus-tag class description FQU82_00001 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) FQU82_00002 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) FQU82_00003 ENOG4105D74 hydrolase FQU82_00005 ENOG4108821 RND type efflux pump FQU82_00006 ENOG4108821 RND type efflux pump FQU82_00007 ENOG4108821 RND type efflux pump FQU82_00008 ENOG4105C5H ABC transporter FQU82_00009 ENOG4105DQR SNARE associated Golgi FQU82_00011 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FQU82_00013 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FQU82_00015 ENOG4105VG0 50S ribosomal protein l34 FQU82_00018 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins FQU82_00021 ENOG4105PGM cation diffusion facilitator family transporter FQU82_00022 ENOG4105T95 Thiol disulfide interChange protein FQU82_00024 ENOG4108UGV hypoxanthine phosphoribosyltransferase FQU82_00026 ENOG4107QUY Guanine deaminase FQU82_00028 ENOG4106032 Glutathionylspermidine synthase FQU82_00030 ENOG4105DU1 integral membrane protein, terc FQU82_00031 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FQU82_00033 ENOG4105DFU Cell wall formation (By similarity) FQU82_00035 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) FQU82_00036 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit FQU82_00037 ENOG4105CVE Lytic murein transglycosylase FQU82_00048 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) FQU82_00055 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase FQU82_00057 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) FQU82_00058 ENOG4105DTN riboflavin biosynthesis protein ribF FQU82_00060 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) FQU82_00061 ENOG4108R86 Transcriptional regulator FQU82_00062 ENOG4108VM9 ABC, transporter FQU82_00063 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component FQU82_00064 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) FQU82_00065 ENOG4105GVF (ABC) transporter FQU82_00066 ENOG4105GVF (ABC) transporter FQU82_00067 ENOG4107QZM n-acetylglutamate synthase FQU82_00070 ENOG4105UBK short-chain dehydrogenase reductase FQU82_00071 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) FQU82_00074 ENOG41062JF Transcriptional regulator FQU82_00097 ENOG4105D6J arsenicaL-resistance protein FQU82_00103 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) FQU82_00107 ENOG4105MZU cell filamentation protein FQU82_00126 ENOG4105HSS phospholipase C FQU82_00128 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase FQU82_00129 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase FQU82_00130 ENOG4105CJR Integral membrane protein (MviN FQU82_00131 ENOG4108V1T peptidylprolyl cis-trans isomerase FQU82_00132 ENOG4108V1T peptidylprolyl cis-trans isomerase FQU82_00133 ENOG4105D75 Capsular exopolysaccharide family FQU82_00135 ENOG4105DAY polysaccharide export protein FQU82_00136 ENOG4107QQG Dehydrogenase FQU82_00137 ENOG4107R5Z Oxidoreductase domain protein FQU82_00138 ENOG4105J5G Transferase hexapeptide repeat containing protein FQU82_00139 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FQU82_00142 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) FQU82_00145 ENOG4105CG5 Glycosyl transferase (Group 1 FQU82_00146 ENOG4108RYC glycosyltransferase FQU82_00147 ENOG4105D3Q Sugar transferase FQU82_00148 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FQU82_00149 ENOG4105C6Y Udp-glucose 6-dehydrogenase FQU82_00151 ENOG4105CMR udp-glucose 4-epimerase FQU82_00152 ENOG4107QKV phosphomannomutase FQU82_00153 ENOG4105DAA L-lactate FQU82_00154 ENOG41073TP transcriptional regulator FQU82_00156 ENOG4105CXG d-lactate dehydrogenase FQU82_00157 ENOG4105CGF Aromatic amino acid aminotransferase FQU82_00158 ENOG4105DRR Transcriptional regulator, GntR family FQU82_00159 ENOG4105CR4 methylisocitrate lyase FQU82_00160 ENOG4105BZN citrate synthase FQU82_00161 ENOG4108I0Z Aconitate hydratase FQU82_00177 ENOG4105D3G Pseudouridine synthase FQU82_00182 ENOG4105EW9 transcriptional regulator AsnC family FQU82_00185 ENOG4105M4H endoribonuclease L-psp FQU82_00186 ENOG4105C85 amino acid FQU82_00187 ENOG4105C85 amino acid FQU82_00189 ENOG4105C26 Dehydrogenase FQU82_00190 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FQU82_00192 ENOG4105C1G acyl-Coa dehydrogenase FQU82_00193 ENOG4105E39 Enoyl-CoA hydratase FQU82_00194 ENOG4105E39 Enoyl-CoA hydratase FQU82_00195 ENOG4105CSH Transporter FQU82_00200 ENOG4105C1G acyl-Coa dehydrogenase FQU82_00205 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) FQU82_00209 ENOG4107PSF BolA-like protein FQU82_00211 ENOG4107QJE Chromosome Partitioning Protein FQU82_00214 ENOG4105DQR SNARE associated Golgi FQU82_00215 ENOG4108VBZ doxx family FQU82_00216 ENOG4106MP8 UPF0754 membrane protein FQU82_00217 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) FQU82_00221 ENOG4105EUB pirin domain protein FQU82_00226 ENOG4107R1I NAD-dependent malic enzyme FQU82_00227 ENOG4105EZR dyp-type peroxidase family protein FQU82_00229 ENOG4105FAV ABC, transporter FQU82_00230 ENOG4105FDK ABC transporter FQU82_00235 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) FQU82_00243 ENOG4108V06 Glutathione peroxidase FQU82_00245 ENOG4107RTG Major Facilitator superfamily FQU82_00246 ENOG4108IND Tetr family transcriptional regulator FQU82_00249 ENOG4105C79 DNA protecting protein DprA FQU82_00256 ENOG4105Y7M Transcriptional regulator, TetR family FQU82_00263 ENOG4105C6T cysteine synthase FQU82_00265 ENOG4105CS1 NAD(P)H quinone oxidoreductase FQU82_00269 ENOG4105CCT upf0313 protein FQU82_00272 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FQU82_00274 ENOG4105C0R drug resistance transporter emrb qaca subfamily FQU82_00275 ENOG4108URH decarboxylase FQU82_00276 ENOG4105EE5 Membrane protein terC FQU82_00278 ENOG4105EN6 Membrane FQU82_00279 ENOG41079KZ Major Facilitator Superfamily FQU82_00280 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FQU82_00281 ENOG4105CEY Amp-dependent synthetase and ligase FQU82_00284 ENOG4105F0N pyrophosphate phospho-hydrolase FQU82_00285 ENOG4105EPF Outer membrane porin FQU82_00287 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FQU82_00289 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FQU82_00290 ENOG4105C0P Mg chelatase subunit ChlI FQU82_00293 ENOG4105BZU Histidine kinase FQU82_00295 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) FQU82_00303 ENOG4108K5H permease YjgP YjgQ family protein FQU82_00304 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) FQU82_00305 ENOG4105CN1 protease FQU82_00306 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FQU82_00307 ENOG4107TUY Histidine kinase FQU82_00309 ENOG41061WM D-Alanyl-D-Alanine FQU82_00311 ENOG4105D6E homoserine dehydrogenase FQU82_00312 ENOG4105T95 Thiol disulfide interChange protein FQU82_00313 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FQU82_00315 ENOG4105CE1 Ferrous iron transport protein b FQU82_00318 ENOG4105CNI cell division protein FtsW FQU82_00319 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) FQU82_00320 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters FQU82_00321 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) FQU82_00326 ENOG4108RNG Permease of the drug metabolite transporter FQU82_00327 ENOG4105DFG type I secretion outer membrane protein FQU82_00328 ENOG4108UTW Plays a role in the regulation of phosphate uptake FQU82_00331 ENOG4108HRK Histidine kinase FQU82_00332 ENOG4108NEV two component transcriptional regulator, LytTR family FQU82_00333 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) FQU82_00338 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS FQU82_00341 ENOG4105GVR general secretion pathway protein D FQU82_00342 ENOG4105TV9 FHA Domain-Containing protein FQU82_00343 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) FQU82_00351 ENOG4105PM1 preprotein translocase subunit SecE FQU82_00352 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) FQU82_00363 ENOG4105D3Y Na H antiporter FQU82_00366 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) FQU82_00369 ENOG4107ZXU DSBA oxidoreductase FQU82_00382 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase FQU82_00383 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FQU82_00389 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) FQU82_00391 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) FQU82_00394 ENOG4105C2N RNA methyltransferase TrmH family group 3 FQU82_00396 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) FQU82_00399 ENOG4107QHF type ii secretion system protein e FQU82_00401 ENOG4107EJC Preprotein translocase subunit SecG FQU82_00405 ENOG4105CHV Transcription elongation factor NusA FQU82_00408 ENOG4105KJM monovalent cation h antiporter subunit g FQU82_00409 ENOG4105W4C monovalent cation H antiporter subunit F FQU82_00410 ENOG4105SC1 monovalent cation H antiporter subunit E FQU82_00411 ENOG4107R4Z monovalent cation h antiporter subunit d FQU82_00412 ENOG4108ZE9 Monovalent cation H antiporter subunit C FQU82_00413 ENOG4105D65 subunit l FQU82_00416 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase FQU82_00417 ENOG41061H0 Monooxygenase FQU82_00420 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FQU82_00422 ENOG4105CSR polyphosphate kinase 2 FQU82_00424 ENOG4105DSY exodeoxyribonuclease V, gamma FQU82_00425 ENOG4107QKA exodeoxyribonuclease V beta FQU82_00426 ENOG4107QYX exodeoxyribonuclease v alpha FQU82_00430 ENOG4107QUT magnesium and cobalt transport protein CorA FQU82_00431 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) FQU82_00432 ENOG4105DVC DnaJ domain protein FQU82_00435 ENOG4105CKD glutathione-regulated potassium-efflux system protein FQU82_00436 ENOG4105C25 Primosomal protein n' FQU82_00437 ENOG4105D7Q type ii secretion system FQU82_00438 ENOG4108VAU general secretion pathway protein G FQU82_00440 ENOG4108Z7R Chaperone CsaA FQU82_00441 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) FQU82_00442 ENOG4108JU5 Magnesium and cobalt efflux protein FQU82_00443 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) FQU82_00444 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase FQU82_00446 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) FQU82_00449 ENOG4105C5X domain protein FQU82_00450 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) FQU82_00452 ENOG4105BZ8 glutamate synthase FQU82_00460 ENOG4107QI1 Mate efflux family protein FQU82_00462 ENOG4105CSA Coproporphyrinogen iii oxidase FQU82_00463 ENOG4105EMU Dehydrogenase FQU82_00464 ENOG4105CBN LysR family transcriptional regulator FQU82_00468 ENOG4105C03 ribonuclease FQU82_00469 ENOG4105EI2 Pseudouridine synthase FQU82_00470 ENOG4107XGZ Hydrolase FQU82_00471 ENOG4105D29 Helix-turn-helix type 11 domain protein FQU82_00474 ENOG4108W5M transcriptional regulator FQU82_00477 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase FQU82_00482 ENOG4105DUM transcriptional regulator, lysR family FQU82_00487 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FQU82_00498 ENOG4105CK2 sodium dicarboxylate symporter FQU82_00500 ENOG4105D1S lipid A biosynthesis FQU82_00501 ENOG4105N14 lysine exporter protein LysE YggA FQU82_00502 ENOG4105C5H ABC transporter FQU82_00503 ENOG41069P5 Protein slyX homolog FQU82_00505 ENOG4105KVH Transcriptional regulator FQU82_00507 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FQU82_00510 ENOG4105C4R Atp-dependent dna helicase FQU82_00511 ENOG4105VFU Rna-binding protein FQU82_00515 ENOG4105CKD glutathione-regulated potassium-efflux system protein FQU82_00516 ENOG4105W0E 50S ribosomal protein L33 FQU82_00517 ENOG4105KDC 50s ribosomal protein l28 FQU82_00518 ENOG4107RGH Aldehyde dehydrogenase FQU82_00520 ENOG4105CIY formyltetrahydrofolate deformylase FQU82_00550 ENOG4105DWV Homoserine O-trans-acetylase FQU82_00552 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) FQU82_00554 ENOG4108ESX Receptor FQU82_00556 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FQU82_00560 ENOG4107GFK fumarate FQU82_00561 ENOG4108DNC Involved in acetate metabolism (By similarity) FQU82_00562 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) FQU82_00563 ENOG4105C01 Dihydroxy-acid dehydratase FQU82_00564 ENOG4108UHU Aldolase FQU82_00565 ENOG4105C6Z Gluconate FQU82_00566 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family FQU82_00567 ENOG4105C26 Dehydrogenase FQU82_00569 ENOG4106HB6 Alpha beta hydrolase FQU82_00572 ENOG4105CN1 protease FQU82_00575 ENOG4105WVQ Fe-S assembly protein IscX FQU82_00579 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) FQU82_00583 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) FQU82_00587 ENOG4105VW4 glutaredoxin 3 FQU82_00589 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) FQU82_00590 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) FQU82_00592 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH FQU82_00593 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FQU82_00594 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FQU82_00595 ENOG4105DJY efflux transporter, rnd family, mfp subunit FQU82_00600 ENOG4105C7K acetolactate synthase FQU82_00601 ENOG4108ZP8 Acetolactate synthase small subunit FQU82_00603 ENOG4105BZU Histidine kinase FQU82_00607 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) FQU82_00610 ENOG4105F8V Hydrolase, tatD family FQU82_00611 ENOG4107QM5 aconitate hydratase FQU82_00613 ENOG4105CUZ uba thif-type nad fad binding protein FQU82_00615 ENOG4107RSM transcriptional regulator FQU82_00617 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FQU82_00620 ENOG4106UX7 integral membrane protein FQU82_00621 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) FQU82_00622 ENOG4105W8H transhydrogenase (subunit alpha FQU82_00623 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) FQU82_00626 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) FQU82_00627 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FQU82_00628 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase FQU82_00629 ENOG4105BZU Histidine kinase FQU82_00630 ENOG4105C6T cysteine synthase FQU82_00633 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FQU82_00635 ENOG4105DXN mazG family FQU82_00636 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein FQU82_00637 ENOG4105DJ0 Poly(A) Polymerase FQU82_00638 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FQU82_00642 ENOG41080Z8 PHOSPHOCARRIER protein FQU82_00643 ENOG4105N42 UPF0307 protein FQU82_00644 ENOG4105CEY Amp-dependent synthetase and ligase FQU82_00647 ENOG4105CYM Glutathione S-transferase FQU82_00648 ENOG4105W39 Membrane FQU82_00651 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) FQU82_00656 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) FQU82_00659 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) FQU82_00661 ENOG4105C9X ppx gppa phosphatase FQU82_00663 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) FQU82_00664 ENOG4105II7 pyrroline-5-carboxylate reductase FQU82_00665 ENOG4108VIA integral membrane protein FQU82_00666 ENOG4105C2M dna polymerase I FQU82_00670 ENOG4107QHF type ii secretion system protein e FQU82_00671 ENOG4108ZHJ Organic hydroperoxide resistance protein FQU82_00672 ENOG4105K56 Transcriptional regulator FQU82_00686 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) FQU82_00687 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) FQU82_00688 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) FQU82_00690 ENOG4105CRQ synthase (Component I) FQU82_00699 ENOG4108Z0R Transferase FQU82_00700 ENOG41072GX Peptidase M22 Glycoprotease FQU82_00703 ENOG4105C4W S-formylglutathione hydrolase FQU82_00705 ENOG4105DJV ribulose-phosphate 3-epimerase FQU82_00706 ENOG4108HCJ Hydrolase FQU82_00708 ENOG4105E3B Multicopper oxidase FQU82_00712 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FQU82_00713 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) FQU82_00714 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) FQU82_00721 ENOG4105ETT transcriptional Regulator, LysR family FQU82_00722 ENOG4105C1G acyl-Coa dehydrogenase FQU82_00723 ENOG4107RGD Major Facilitator superfamily FQU82_00724 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FQU82_00728 ENOG4107EFR Flavocytochrome c FQU82_00729 ENOG4106P55 Transcriptional regulator FQU82_00732 ENOG4106P55 Transcriptional regulator FQU82_00733 ENOG4108NIW Leucine export protein LeuE FQU82_00734 ENOG4105ETT transcriptional Regulator, LysR family FQU82_00736 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) FQU82_00737 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) FQU82_00748 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FQU82_00750 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FQU82_00751 ENOG4107EXC regulatoR FQU82_00752 ENOG4105E0F Histidine kinase FQU82_00754 ENOG4105BZU Histidine kinase FQU82_00758 ENOG4105GKE subunit e FQU82_00759 ENOG4107QIZ NADH dehydrogenase FQU82_00760 ENOG4108IEH NADH dehydrogenase subunit g FQU82_00763 ENOG4107UFS subunit j FQU82_00765 ENOG4105D65 subunit l FQU82_00766 ENOG4105C8S subunit m FQU82_00770 ENOG4105DUM transcriptional regulator, lysR family FQU82_00771 ENOG4105DP0 ferredoxin-NADP reductase FQU82_00776 ENOG4105CBX hi0933 family FQU82_00777 ENOG4105K6H D-cysteine desulfhydrase FQU82_00783 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) FQU82_00785 ENOG4105D1F ATP-binding protein FQU82_00786 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) FQU82_00795 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) FQU82_00797 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY FQU82_00800 ENOG4105HF0 Membrane FQU82_00802 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) FQU82_00806 ENOG4106UW1 Major Facilitator superfamily FQU82_00807 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase FQU82_00808 ENOG4108K4C ec 3.1.3.12 FQU82_00809 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FQU82_00811 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) FQU82_00812 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FQU82_00814 ENOG4105FE9 pseudouridine synthase FQU82_00815 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) FQU82_00816 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) FQU82_00817 ENOG4107RTD sua5 ycio yrdc ywlc family protein FQU82_00818 ENOG4108BPE -transporting atpase FQU82_00819 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein FQU82_00821 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FQU82_00822 ENOG4105CHR reductase FQU82_00824 ENOG4109066 lysm domain bon superfamily protein FQU82_00825 ENOG4105DWF phosphomethylpyrimidine kinase FQU82_00827 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) FQU82_00833 ENOG4105C5T Phosphoribosyl pyrophosphate synthase FQU82_00838 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) FQU82_00841 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) FQU82_00842 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane FQU82_00843 ENOG4105C34 Pseudouridine synthase FQU82_00844 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase FQU82_00848 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding FQU82_00851 ENOG4105EJC lysr family transcriptional regulator FQU82_00852 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FQU82_00853 ENOG4105C94 Transporter FQU82_00855 ENOG4105DVW rieske (2Fe-2S) FQU82_00856 ENOG4105C26 Dehydrogenase FQU82_00857 ENOG4105E3J oxidoreductase FQU82_00860 ENOG4105C4K Nad synthetase FQU82_00862 ENOG4105EUB pirin domain protein FQU82_00863 ENOG4108YXA Membrane FQU82_00872 ENOG4105KEG ribosomal-protein-alanine acetyltransferase FQU82_00874 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) FQU82_00875 ENOG4105C3M thioredoxin reductase FQU82_00876 ENOG4105CNU cell division protein FtsK FQU82_00880 ENOG4107QMS site-determining protein FQU82_00883 ENOG4106HNH Acyl-transferase FQU82_00884 ENOG4108ZG0 Ompa motb domain protein FQU82_00885 ENOG4105C4R Atp-dependent dna helicase FQU82_00887 ENOG4107QKV phosphomannomutase FQU82_00890 ENOG4105E7A Glutamine amidotransferase FQU82_00895 ENOG41090R7 Ferric uptake FQU82_00896 ENOG4105CZX twitching motility protein FQU82_00897 ENOG4105CZX twitching motility protein FQU82_00898 ENOG4105DFA alanine racemase domain protein FQU82_00899 ENOG4105EYH Exonuclease FQU82_00900 ENOG4107RH8 nuclease SbcCD subunit D FQU82_00904 ENOG4105ECP epimerase FQU82_00905 ENOG4105MWK D-amino acid dehydrogenase, small subunit FQU82_00906 ENOG4105D52 delta-aminolevulinic acid dehydratase FQU82_00907 ENOG4108VUY thioesterase Superfamily protein FQU82_00908 ENOG4105CW7 secretion protein, HlyD family FQU82_00909 ENOG4105C0R drug resistance transporter emrb qaca subfamily FQU82_00910 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) FQU82_00912 ENOG4105DFP Integrase FQU82_00922 ENOG4108UUM single-stranded DNA-binding protein FQU82_00932 ENOG4105M6W Crispr-associated protein, Csy3 family FQU82_00948 ENOG4105C54 Major Facilitator superfamily FQU82_00949 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FQU82_00959 ENOG4105D5Q Arginine ornithine antiporter FQU82_00960 ENOG4107QK5 Homocysteine s-methyltransferase FQU82_00965 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) FQU82_00966 ENOG4105C94 Transporter FQU82_00967 ENOG4105C94 Transporter FQU82_00971 ENOG4105CKI cobalamin synthesis protein FQU82_00973 ENOG4108VWS Yaeq family FQU82_00975 ENOG4107BJW polysaccharide deacetylase FQU82_00976 ENOG4105CND Glycosyl transferase, family 2 FQU82_00978 ENOG4106YT9 Enoyl-CoA hydratase FQU82_00981 ENOG41069M3 Transcriptional regulator FQU82_00985 ENOG4105CHR reductase FQU82_00988 ENOG4105DJB Major Facilitator Superfamily FQU82_00990 ENOG4108MXF Alpha Beta Hydrolase FQU82_00991 ENOG4105CHR reductase FQU82_00994 ENOG4105C7K acetolactate synthase FQU82_00996 ENOG4105CSH Transporter FQU82_00997 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FQU82_00998 ENOG4105CSV Glutaminase FQU82_00999 ENOG4108R6W Transcriptional regulator, ARAC family FQU82_01000 ENOG4105EU0 Major facilitator Superfamily FQU82_01001 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) FQU82_01003 ENOG4108PZW LysR family Transcriptional regulator FQU82_01005 ENOG4105CSP Major Facilitator Superfamily FQU82_01008 ENOG4105C3R Methionine synthase FQU82_01009 ENOG4105CJ3 phosphate transporter FQU82_01013 ENOG4105E6M Sulphatase-modifying factor protein FQU82_01014 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) FQU82_01017 ENOG4107RNH Outer membrane receptor FepA FQU82_01021 ENOG4108UJV acyl-CoA thioesterase i FQU82_01022 ENOG4108I0Y (ABC) transporter FQU82_01023 ENOG4105CV6 ABC transporter, permease FQU82_01024 ENOG4107U91 Rhomboid family FQU82_01028 ENOG4105C5Q Transcriptional regulator FQU82_01030 ENOG4107QZF nitrite reductase NADPH large subunit FQU82_01031 ENOG4105VCQ rubredoxin FQU82_01035 ENOG4108MRJ FQU82_01038 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) FQU82_01041 ENOG4105D4T Citrate transporter FQU82_01042 ENOG4105C37 (CBS) domain FQU82_01044 ENOG4107RET Isocitrate lyase FQU82_01050 ENOG4105CQM Urea amidohydrolase subunit alpha FQU82_01052 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) FQU82_01055 ENOG4106H78 methyltransferase FQU82_01056 ENOG4105CJN penicillin-binding protein FQU82_01060 ENOG4105CSM endonuclease III FQU82_01061 ENOG4108R3D Electron transport complex FQU82_01062 ENOG4105D82 Glutamate dehydrogenase FQU82_01064 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b FQU82_01069 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase FQU82_01134 ENOG4105DR5 peptidase FQU82_01143 ENOG4105DIJ Phosphoethanolamine transferase FQU82_01150 ENOG4107RAQ aminopeptidase FQU82_01151 ENOG4105D0A hydroxylase FQU82_01152 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family FQU82_01156 ENOG4108ZUB Lysine exporter protein (Lyse ygga) FQU82_01157 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) FQU82_01159 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) FQU82_01161 ENOG4105W4M Transport-associated protein FQU82_01163 ENOG4105E09 nadh pyrophosphatase FQU82_01165 ENOG4107RZZ dna polymerase iii epsilon subunit FQU82_01166 ENOG4105E9H Lytic Murein transglycosylase FQU82_01166 ENOG4105E9H Lytic Murein transglycosylase FQU82_01168 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component FQU82_01169 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component FQU82_01170 ENOG4108JQ5 ABC transporter FQU82_01174 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) FQU82_01178 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FQU82_01180 ENOG4105DFP Integrase FQU82_01195 ENOG4105W1Y Transcriptional regulator FQU82_01198 ENOG4105W1Y Transcriptional regulator FQU82_01201 ENOG4105MZU cell filamentation protein FQU82_01203 ENOG4105CVR type I restriction-modification system FQU82_01208 ENOG4105R8C Transcriptional regulator FQU82_01209 ENOG4105CS6 Rhs element vgr protein FQU82_01211 ENOG4108M3P Membrane FQU82_01212 ENOG4105D01 (LipO)protein FQU82_01215 ENOG4106B0W Curli production assembly transport component CsgG FQU82_01217 ENOG4107Y60 (LipO)protein FQU82_01219 ENOG4105C85 amino acid FQU82_01221 ENOG4105CUB amino acid FQU82_01225 ENOG4105C26 Dehydrogenase FQU82_01229 ENOG4105F4X arginine FQU82_01230 ENOG4105C85 amino acid FQU82_01235 ENOG4107RGH Aldehyde dehydrogenase FQU82_01236 ENOG4108ZX5 transcriptional regulator FQU82_01237 ENOG4105DJP Membrane FQU82_01238 ENOG4105CTX dehydratase FQU82_01239 ENOG4105DJB Major Facilitator Superfamily FQU82_01240 ENOG4105EQX glucarate dehydratase FQU82_01242 ENOG4105CZJ Aldehyde dehydrogenase FQU82_01243 ENOG4105JXH GntR family transcriptional regulator FQU82_01246 ENOG4105NI3 Protein of unknown function (DUF3237) FQU82_01247 ENOG4105EPF Outer membrane porin FQU82_01248 ENOG4105C1G acyl-Coa dehydrogenase FQU82_01251 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase FQU82_01252 ENOG4108SC4 )-transporter FQU82_01255 ENOG4105E3J oxidoreductase FQU82_01257 ENOG4105D2S major facilitator superfamily FQU82_01258 ENOG4105EPF Outer membrane porin FQU82_01262 ENOG4107RN6 Monooxygenase FQU82_01264 ENOG4105JQZ Methyltransferase FQU82_01265 ENOG4105F95 Monooxygenase FQU82_01272 ENOG4105F95 Monooxygenase FQU82_01274 ENOG4105C7N Xanthine uracil vitamin C permease FQU82_01275 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) FQU82_01276 ENOG4105CPW cytochrome b561 FQU82_01278 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) FQU82_01280 ENOG4105CFH Aspartokinase FQU82_01291 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) FQU82_01292 ENOG4105W7J DNA binding FQU82_01310 ENOG4107ZQ5 Phage-associated protein, HI1409 family FQU82_01315 ENOG41090AG Bacteriophage protein FQU82_01340 ENOG4105DFP Integrase FQU82_01342 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FQU82_01344 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis FQU82_01347 ENOG4105CPC Aldo Keto reductase FQU82_01348 ENOG4107RYR Transcriptional regulator, Crp Fnr family FQU82_01349 ENOG4108UKZ OsmC family FQU82_01352 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FQU82_01358 ENOG4105CD3 dihydroorotase FQU82_01359 ENOG4108ZG0 Ompa motb domain protein FQU82_01361 ENOG4108TGY Glutathione S-transferase FQU82_01365 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) FQU82_01367 ENOG4108K3A Glutathione S-transferase FQU82_01369 ENOG4108JU3 Alkyl hydroperoxide reductase FQU82_01371 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) FQU82_01373 ENOG4105D3R alkyl hydroperoxide reductase FQU82_01374 ENOG4105CQ7 ATP-dependent helicase FQU82_01377 ENOG4105D2S major facilitator superfamily FQU82_01378 ENOG4105DKK Benzoate FQU82_01379 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase FQU82_01380 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein FQU82_01381 ENOG4108UKV benzoate 1,2-dioxygenase FQU82_01382 ENOG4105FUY alpha subunit FQU82_01383 ENOG4108KB2 LysR family Transcriptional regulator FQU82_01393 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) FQU82_01400 ENOG410829K Lysine exporter protein (Lyse ygga) FQU82_01401 ENOG4105VEQ Cold shock protein FQU82_01403 ENOG4105II7 pyrroline-5-carboxylate reductase FQU82_01409 ENOG4107YPT transcriptional regulator FQU82_01424 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) FQU82_01425 ENOG4105C4R Atp-dependent dna helicase FQU82_01427 ENOG4108NF7 phage-type endonuclease FQU82_01469 ENOG4105C2X Arabinose 5-phosphate isomerase FQU82_01470 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase FQU82_01472 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA FQU82_01473 ENOG4108IUZ ABC transporter FQU82_01483 ENOG4105DFG type I secretion outer membrane protein FQU82_01491 ENOG4108Z4U Ferredoxin FQU82_01495 ENOG4107AQZ Membrane FQU82_01496 ENOG4105BZU Histidine kinase FQU82_01497 ENOG4105D1S lipid A biosynthesis FQU82_01499 ENOG4105D2S major facilitator superfamily FQU82_01503 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) FQU82_01509 ENOG4108WAV Transcriptional regulator FQU82_01510 ENOG4105C5A transporter FQU82_01514 ENOG4108JIK carboxylase FQU82_01515 ENOG4107R4J Chloride channel FQU82_01516 ENOG4105D5K Hemolysin activator protein FQU82_01517 ENOG4105CKT filamentous hemagglutinin FQU82_01520 ENOG4105R8C Transcriptional regulator FQU82_01522 ENOG4105E2A Dehydrogenase FQU82_01525 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FQU82_01526 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF FQU82_01530 ENOG4105MRR Transcriptional regulator (By similarity) FQU82_01532 ENOG4108HW3 (ABC) transporter FQU82_01546 ENOG4105UYK outer membrane protein a FQU82_01548 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FQU82_01554 ENOG4105EMY transcriptional regulator FQU82_01556 ENOG4107Y2X deaminase FQU82_01557 ENOG4105DJ2 Major Facilitator Superfamily FQU82_01560 ENOG4105WPN DNA integration recombination invertion protein FQU82_01562 ENOG4108Z4X TRANSCRIPTIONal FQU82_01563 ENOG4108Z4X TRANSCRIPTIONal FQU82_01567 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FQU82_01576 ENOG4105CZJ Aldehyde dehydrogenase FQU82_01577 ENOG4107QTZ amino acid FQU82_01578 ENOG4105EJQ L-serine dehydratase FQU82_01579 ENOG4105DXM phenylacetic acid degradation protein FQU82_01580 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit FQU82_01581 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit FQU82_01582 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit FQU82_01583 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit FQU82_01584 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FQU82_01585 ENOG4105E39 Enoyl-CoA hydratase FQU82_01586 ENOG4108UKI Enoyl-CoA hydratase FQU82_01587 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FQU82_01588 ENOG4105CHU acetyl-coa acetyltransferase FQU82_01589 ENOG4105DZS Phenylacetate-CoA ligase FQU82_01590 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein FQU82_01592 ENOG4107YAU phenylacetic acid degradation protein FQU82_01601 ENOG4105CF7 AraC family transcriptional regulator FQU82_01604 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FQU82_01605 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase FQU82_01606 ENOG4105CSP Major Facilitator Superfamily FQU82_01607 ENOG4107VGR Catalase FQU82_01608 ENOG4105CPW cytochrome b561 FQU82_01612 ENOG4108MXF Alpha Beta Hydrolase FQU82_01613 ENOG4105MXW flavin reductase domain protein, FMN-binding FQU82_01614 ENOG4108M8W Monooxygenase FQU82_01615 ENOG4105C26 Dehydrogenase FQU82_01616 ENOG4105ETS cytosine purines uracil thiamine allantoin FQU82_01618 ENOG4105C26 Dehydrogenase FQU82_01619 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase FQU82_01620 ENOG4105HEI LysR family (Transcriptional regulator FQU82_01622 ENOG4107HP6 Transcriptional regulator FQU82_01623 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase FQU82_01625 ENOG4105C4Y ABC transporter FQU82_01626 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FQU82_01627 ENOG4107RCV ABC transporter, permease FQU82_01629 ENOG4107STF Involved in phosphonate degradation (By similarity) FQU82_01630 ENOG4108KAZ Involved in phosphonate degradation (By similarity) FQU82_01631 ENOG4107RGD Major Facilitator superfamily FQU82_01632 ENOG4105C1G acyl-Coa dehydrogenase FQU82_01635 ENOG4108UKI Enoyl-CoA hydratase FQU82_01636 ENOG4105EA8 2-Nitropropane dioxygenase FQU82_01637 ENOG4105EQ0 Major Facilitator superfamily FQU82_01639 ENOG4105CHU acetyl-coa acetyltransferase FQU82_01640 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FQU82_01641 ENOG4105CHR reductase FQU82_01642 ENOG4105E39 Enoyl-CoA hydratase FQU82_01643 ENOG4105C1G acyl-Coa dehydrogenase FQU82_01644 ENOG4107RGD Major Facilitator superfamily FQU82_01645 ENOG4107QP7 CoA-transferase subunit A FQU82_01646 ENOG4107QNJ CoA-transferase subunit B FQU82_01648 ENOG4105EQ0 Major Facilitator superfamily FQU82_01650 ENOG4105CSU acyl-Coa dehydrogenase FQU82_01653 ENOG4105CC0 LysR family Transcriptional regulator FQU82_01656 ENOG4105E39 Enoyl-CoA hydratase FQU82_01657 ENOG4107QX3 carboxylase FQU82_01658 ENOG4105C1G acyl-Coa dehydrogenase FQU82_01659 ENOG4105R8C Transcriptional regulator FQU82_01660 ENOG4105CEY Amp-dependent synthetase and ligase FQU82_01664 ENOG4105HEI LysR family (Transcriptional regulator FQU82_01675 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FQU82_01679 ENOG4105KT5 UmuD protein FQU82_01681 ENOG4105EW9 transcriptional regulator AsnC family FQU82_01683 ENOG4105BZU Histidine kinase FQU82_01684 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FQU82_01686 ENOG4105EAD ABC transporter FQU82_01687 ENOG4108HW4 amino acid AbC transporter FQU82_01688 ENOG4105CDA abc transporter atp-binding protein FQU82_01689 ENOG4107RP9 extracellular solute-binding protein, family 3 FQU82_01690 ENOG4105CT1 (ABC) transporter FQU82_01691 ENOG4105EXG Transcriptional regulator FQU82_01693 ENOG4105C9B Cysteine desulfurase FQU82_01694 ENOG4105ESN nucleotide-binding protein FQU82_01695 ENOG4105D7W serine acetyltransferase FQU82_01697 ENOG4105CHR reductase FQU82_01698 ENOG4105CBN LysR family transcriptional regulator FQU82_01699 ENOG4105CYM Glutathione S-transferase FQU82_01700 ENOG4108SHQ Glutathione S-transferase FQU82_01701 ENOG4105CMU LysR family (Transcriptional regulator FQU82_01702 ENOG4105VAW lrga family FQU82_01703 ENOG41067MG lrgb family FQU82_01707 ENOG4105DXI Major Facilitator superfamily FQU82_01709 ENOG4105ETT transcriptional Regulator, LysR family FQU82_01711 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase FQU82_01712 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) FQU82_01715 ENOG4105PSI phosphoribosyl-dephospho-CoA transferase FQU82_01716 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FQU82_01719 ENOG4108K70 Transcriptional regulator FQU82_01720 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FQU82_01722 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FQU82_01723 ENOG4105C4M (Ubiquinol oxidase) subunit I FQU82_01727 ENOG4105C54 Major Facilitator superfamily FQU82_01729 ENOG4106FTQ Taurine ABC transporter, periplasmic FQU82_01730 ENOG4108IY8 ABC, transporter FQU82_01731 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FQU82_01732 ENOG4105E2B Taurine dioxygenase FQU82_01734 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease FQU82_01736 ENOG4105CBN LysR family transcriptional regulator FQU82_01738 ENOG4105CPN adenine deaminase FQU82_01741 ENOG41082YX Transcriptional regulator, arsr family FQU82_01742 ENOG4105D6J arsenicaL-resistance protein FQU82_01743 ENOG4108KB2 LysR family Transcriptional regulator FQU82_01746 ENOG4108JU3 Alkyl hydroperoxide reductase FQU82_01751 ENOG4105C0B DNA polymerase III (alpha subunit) FQU82_01754 ENOG4105CHM Aminotransferase FQU82_01756 ENOG4108V06 Glutathione peroxidase FQU82_01757 ENOG4105E7U AraC family transcriptional regulator FQU82_01763 ENOG4105ZED uncharacterized protein ygaH FQU82_01764 ENOG4108UMN azlc family FQU82_01769 ENOG4105C3G gtp-binding protein FQU82_01770 ENOG4108UMI ABC transporter, permease FQU82_01771 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FQU82_01772 ENOG4105D01 (LipO)protein FQU82_01773 ENOG4105D01 (LipO)protein FQU82_01776 ENOG4107T8P acyl-Coa dehydrogenase FQU82_01779 ENOG4105EAD ABC transporter FQU82_01780 ENOG4105DRP amino acid AbC transporter FQU82_01781 ENOG4105CDA abc transporter atp-binding protein FQU82_01783 ENOG4105EW9 transcriptional regulator AsnC family FQU82_01786 ENOG41067SE Tetr family transcriptional regulator FQU82_01788 ENOG4105F5W AtP-binding protein FQU82_01791 ENOG4105D85 methylase FQU82_01792 ENOG4105F6A helicase FQU82_01794 ENOG4105ECI YeeC-like protein FQU82_01801 ENOG4105CC0 LysR family Transcriptional regulator FQU82_01803 ENOG4105ETS cytosine purines uracil thiamine allantoin FQU82_01805 ENOG4108IPJ Membrane FQU82_01810 ENOG4105GQR Chaperone FQU82_01811 ENOG4105X0I Fimbrial FQU82_01815 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) FQU82_01816 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) FQU82_01820 ENOG4108HWY Beta-lactamase FQU82_01825 ENOG4105CV1 Transketolase (EC 2.2.1.1) FQU82_01827 ENOG4108YYC ycei family FQU82_01829 ENOG4108T58 Mg2 transport protein CorA FQU82_01832 ENOG4105YGK Pfam:UPF0157 FQU82_01833 ENOG4105C26 Dehydrogenase FQU82_01834 ENOG4105EW9 transcriptional regulator AsnC family FQU82_01835 ENOG4105CK7 Sodium proline symporter FQU82_01836 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) FQU82_01838 ENOG4108ZX5 transcriptional regulator FQU82_01840 ENOG4105BZ1 (ABC) transporter FQU82_01841 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme FQU82_01842 ENOG4105XPP Protein of unknown function (DUF1275) FQU82_01844 ENOG41080HT Transcriptional regulator, arsr family FQU82_01846 ENOG4105EZE Cupin 4 family protein FQU82_01847 ENOG4108UHJ MAF-like protein FQU82_01851 ENOG4105D2N Aldolase FQU82_01852 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) FQU82_01853 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) FQU82_01854 ENOG4105EHM Aminoglycoside phosphotransferase FQU82_01855 ENOG4108S0S Nucleotidyl transferase FQU82_01857 ENOG4107QJE Chromosome Partitioning Protein FQU82_01858 ENOG4105FA0 parb-like partition protein FQU82_01861 ENOG4105BZ1 (ABC) transporter FQU82_01862 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) FQU82_01864 ENOG4107QRG dna polymerase iii FQU82_01866 ENOG4105F8V Hydrolase, tatD family FQU82_01871 ENOG4108RTD type II secretion system protein K FQU82_01875 ENOG4108Z6B deaminase FQU82_01878 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) FQU82_01879 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) FQU82_01883 ENOG4107RN6 Monooxygenase FQU82_01885 ENOG4105D6Z AFG1 family ATPase FQU82_01886 ENOG4107QP3 malate synthase g FQU82_01887 ENOG4105SG9 biopolymer transport protein, ExbD FQU82_01895 ENOG4105DGW oligopeptidase A FQU82_01897 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FQU82_01901 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase FQU82_01904 ENOG4105K4T epimerase FQU82_01905 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) FQU82_01909 ENOG4108JA2 transcriptioN-repair coupling factor FQU82_01911 ENOG4105F8J Adenylate Guanylate cyclase FQU82_01912 ENOG4108ZIT Ferredoxin, 2FE-2S FQU82_01915 ENOG4108Z4V iron-sulfur cluster assembly FQU82_01916 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins FQU82_01918 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family FQU82_01921 ENOG4105K70 DNA-binding protein FQU82_01922 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) FQU82_01923 ENOG4105E7U AraC family transcriptional regulator FQU82_01924 ENOG4105EEF Alkane 1-monooxygenase FQU82_01925 ENOG4105C1G acyl-Coa dehydrogenase FQU82_01926 ENOG4105C1G acyl-Coa dehydrogenase FQU82_01929 ENOG4108Z66 YbaK ebsC protein FQU82_01933 ENOG4105DUU IucA IucC family protein FQU82_01934 ENOG4105DJU Siderophore biosynthesis protein FQU82_01936 ENOG4105JSC dimethylmenaquinone methyltransferase FQU82_01942 ENOG4107VXZ Hydrolase FQU82_01944 ENOG4108YZT Adenosylcobinamide kinase FQU82_01945 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) FQU82_01946 ENOG4107TB6 phosphoglycerate mutase FQU82_01949 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FQU82_01950 ENOG4107TSN permease FQU82_01954 ENOG4105CNM Receptor FQU82_01955 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) FQU82_01958 ENOG4105CJ1 ABC, transporter FQU82_01959 ENOG4107QWP ABC-2 type transporter FQU82_01960 ENOG4107QWP ABC-2 type transporter FQU82_01965 ENOG4105K59 histidine triad (HIT) protein FQU82_01971 ENOG4105F2W methyltransferase FQU82_01973 ENOG4105C28 cystathionine FQU82_01976 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) FQU82_01977 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) FQU82_01978 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) FQU82_01980 ENOG4105BZU Histidine kinase FQU82_01983 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) FQU82_01984 ENOG4107R0V Pyruvate dehydrogenase FQU82_01985 ENOG4105CPP Dehydrogenase, E1 component FQU82_01988 ENOG4105CHR reductase FQU82_01990 ENOG4105FFC UPF0187 protein FQU82_01992 ENOG4107QPB Beta-lactamase domain protein FQU82_01994 ENOG4108VCT Sulfite exporter TauE/SafE FQU82_01997 ENOG4105UEI Transcriptional Regulator AraC Family FQU82_01998 ENOG4105KVH Transcriptional regulator FQU82_01999 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) FQU82_02001 ENOG4105FDP GntR family transcriptional regulator FQU82_02004 ENOG4106FTQ Taurine ABC transporter, periplasmic FQU82_02005 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component FQU82_02009 ENOG4105CSH Transporter FQU82_02011 ENOG4108IJ0 Aspartate ammonia-lyase FQU82_02014 ENOG4107YNJ LysR family Transcriptional regulator FQU82_02016 ENOG4105CHU acetyl-coa acetyltransferase FQU82_02017 ENOG4105CRW Short chain fatty acid transporter FQU82_02020 ENOG4108M0I Transcriptional regulator FQU82_02024 ENOG4108IND Tetr family transcriptional regulator FQU82_02026 ENOG4105CY2 Citrate transporter FQU82_02027 ENOG4105DTD Dehydrogenase FQU82_02028 ENOG4105CF7 AraC family transcriptional regulator FQU82_02029 ENOG4105D2S major facilitator superfamily FQU82_02031 ENOG4105CHR reductase FQU82_02036 ENOG4105F57 Anthranilate dioxygenase reductase FQU82_02037 ENOG4108YS2 small subunit FQU82_02038 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit FQU82_02039 ENOG4105F4R Transcriptional regulator mode FQU82_02040 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FQU82_02041 ENOG4105E0C molybdate abc transporter FQU82_02042 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) FQU82_02043 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase FQU82_02044 ENOG4105WQI isochorismatase FQU82_02046 ENOG4107T31 5'-nucleotidase FQU82_02052 ENOG4108IGT Dipeptidase FQU82_02056 ENOG4107RZC phospholipase d FQU82_02066 ENOG4105X0I Fimbrial FQU82_02069 ENOG4105BZS acriflavin resistance protein FQU82_02070 ENOG4105C1P efflux transporter, rnd family, mfp subunit FQU82_02071 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FQU82_02072 ENOG4105E0F Histidine kinase FQU82_02073 ENOG4108821 RND type efflux pump FQU82_02074 ENOG4108R6W Transcriptional regulator, ARAC family FQU82_02077 ENOG4108BAS reductase FQU82_02080 ENOG4108UMS Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity) FQU82_02089 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) FQU82_02113 ENOG4105C5T Phosphoribosyl pyrophosphate synthase FQU82_02117 ENOG4105E0A ABC, transporter FQU82_02118 ENOG4105EHG Permease protein FQU82_02120 ENOG4105DQ4 alcohol dehydrogenase FQU82_02123 ENOG4105CF7 AraC family transcriptional regulator FQU82_02124 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FQU82_02126 ENOG4105EXW epimerase dehydratase FQU82_02127 ENOG4105DDW LysR family Transcriptional regulator FQU82_02129 ENOG4105C01 Dihydroxy-acid dehydratase FQU82_02130 ENOG4105CZJ Aldehyde dehydrogenase FQU82_02133 ENOG4105CW7 secretion protein, HlyD family FQU82_02136 ENOG4106P55 Transcriptional regulator FQU82_02139 ENOG4105FDP GntR family transcriptional regulator FQU82_02146 ENOG4105CKT filamentous hemagglutinin FQU82_02147 ENOG4105D5K Hemolysin activator protein FQU82_02150 ENOG4105CEY Amp-dependent synthetase and ligase FQU82_02152 ENOG4105CSU acyl-Coa dehydrogenase FQU82_02154 ENOG4105KF3 Short-chain dehydrogenase reductase Sdr FQU82_02155 ENOG41061TZ Short-chain dehydrogenase reductase Sdr FQU82_02156 ENOG41061TZ Short-chain dehydrogenase reductase Sdr FQU82_02157 ENOG4108PTX LysR family Transcriptional regulator FQU82_02158 ENOG4107Z3H Transcriptional regulator, TetR family FQU82_02163 ENOG4108Z6Z Transcriptional regulator FQU82_02166 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FQU82_02169 ENOG4105CZJ Aldehyde dehydrogenase FQU82_02173 ENOG4107EJG GntR family transcriptional regulator FQU82_02175 ENOG4108KB2 LysR family Transcriptional regulator FQU82_02176 ENOG4105DTQ mandelate racemase muconate lactonizing FQU82_02177 ENOG4105NN7 muconolactone delta-isomerase FQU82_02179 ENOG4107QP7 CoA-transferase subunit A FQU82_02180 ENOG4107QNJ CoA-transferase subunit B FQU82_02181 ENOG4105CHU acetyl-coa acetyltransferase FQU82_02182 ENOG4105F2Z 3-oxoadipate enol-lactonase FQU82_02185 ENOG4105C26 Dehydrogenase FQU82_02187 ENOG4105F11 amine oxidase FQU82_02191 ENOG4105CHR reductase FQU82_02193 ENOG4105FUY alpha subunit FQU82_02197 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FQU82_02199 ENOG4105DNH Major Facilitator FQU82_02204 ENOG4105C1G acyl-Coa dehydrogenase FQU82_02205 ENOG4108PTX LysR family Transcriptional regulator FQU82_02206 ENOG4107HP6 Transcriptional regulator FQU82_02209 ENOG4105MD1 YeeE YedE family protein FQU82_02211 ENOG4105DZG Dehydrogenase FQU82_02212 ENOG4105TW1 Carbohydrate-selective porin OprB FQU82_02213 ENOG4106JPM 3-dehydroshikimate dehydratase FQU82_02214 ENOG4105FF2 Type I DHQase FQU82_02215 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha FQU82_02216 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta FQU82_02217 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase FQU82_02218 ENOG4105D2S major facilitator superfamily FQU82_02219 ENOG4105F2Z 3-oxoadipate enol-lactonase FQU82_02220 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase FQU82_02221 ENOG4105CHU acetyl-coa acetyltransferase FQU82_02222 ENOG4107QNJ CoA-transferase subunit B FQU82_02223 ENOG4107QP7 CoA-transferase subunit A FQU82_02225 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) FQU82_02226 ENOG4107VMU Membrane FQU82_02235 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FQU82_02238 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FQU82_02240 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FQU82_02241 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) FQU82_02247 ENOG4105C7B Threonine dehydratase FQU82_02249 ENOG4105CZN Potassium uptake protein FQU82_02250 ENOG4105HDD phospholipase FQU82_02253 ENOG4105E0K tonB-dependent siderophore receptor FQU82_02256 ENOG4105PV3 Inner membrane protein yqiJ FQU82_02258 ENOG4105C4M (Ubiquinol oxidase) subunit I FQU82_02259 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FQU82_02262 ENOG41068P6 UPF0319 protein FQU82_02264 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) FQU82_02269 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FQU82_02270 ENOG4105C8Y Acetylornithine aminotransferase FQU82_02271 ENOG4105M2J Glutaredoxin FQU82_02273 ENOG4105CC0 LysR family Transcriptional regulator FQU82_02274 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FQU82_02275 ENOG4105CWM branched-chain amino acid transport system II carrier protein FQU82_02280 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FQU82_02281 ENOG4105DE4 1-phosphofructokinase FQU82_02282 ENOG4105DM4 PTS System FQU82_02286 ENOG4105BZU Histidine kinase FQU82_02288 ENOG4105D8V Glucose sorbosone dehydrogenase FQU82_02289 ENOG4108RAV Conserved protein FQU82_02290 ENOG4105CHH sulfate transporter FQU82_02293 ENOG4105C85 amino acid FQU82_02295 ENOG4105F7P transcriptional regulator AsnC family FQU82_02300 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 FQU82_02301 ENOG4105VEJ Heat shock protein FQU82_02303 ENOG4105Y3E Modulates RecA activity (By similarity) FQU82_02305 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) FQU82_02310 ENOG4105DZP Membrane-associated zinc metalloprotease FQU82_02312 ENOG4105KNE Phosphatidate cytidylyltransferase FQU82_02313 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) FQU82_02317 ENOG4105CUX Signal transduction histidine kinase FQU82_02318 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FQU82_02329 ENOG4105CMR udp-glucose 4-epimerase FQU82_02330 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) FQU82_02334 ENOG4105T38 integral membrane protein FQU82_02335 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FQU82_02337 ENOG4105CVM Molybdenum cofactor synthesis domain protein FQU82_02338 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FQU82_02346 ENOG4108IFG nitrite reductase, (NAD(P)H) FQU82_02347 ENOG4107QZF nitrite reductase NADPH large subunit FQU82_02349 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FQU82_02353 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein FQU82_02354 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FQU82_02356 ENOG4105D8G Major Facilitator superfamily FQU82_02360 ENOG4105CBC glutamate synthase FQU82_02366 ENOG4105C0A alcohol dehydrogenase FQU82_02368 ENOG4105HSS phospholipase C FQU82_02370 ENOG4107QMP dna polymerase iii subunits gamma and tau FQU82_02375 ENOG4105CHR reductase FQU82_02376 ENOG4105CHU acetyl-coa acetyltransferase FQU82_02378 ENOG4105C5Q Transcriptional regulator FQU82_02379 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FQU82_02380 ENOG4108NIW Leucine export protein LeuE FQU82_02381 ENOG4105EW9 transcriptional regulator AsnC family FQU82_02382 ENOG4105DKK Benzoate FQU82_02384 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic FQU82_02389 ENOG41081QV Universal stress protein FQU82_02390 ENOG4105C5H ABC transporter FQU82_02394 ENOG4105CNM Receptor FQU82_02400 ENOG4105CUY Mechanosensitive ion channel FQU82_02402 ENOG4105R8C Transcriptional regulator FQU82_02404 ENOG4105EW9 transcriptional regulator AsnC family FQU82_02405 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) FQU82_02410 ENOG4108D1K outer membrane usher protein FQU82_02413 ENOG4105CD8 aminopeptidase N FQU82_02418 ENOG4107QUV Domain protein FQU82_02419 ENOG4105C0A alcohol dehydrogenase FQU82_02421 ENOG4107RR1 TRANSCRIPTIONal FQU82_02423 ENOG4107R55 ethanolamine transporter FQU82_02424 ENOG4105CPD ethanolamine ammonia-lyase FQU82_02425 ENOG4107FQ9 ethanolamine ammonia-lyase FQU82_02426 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) FQU82_02429 ENOG4105F10 Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity) FQU82_02431 ENOG4108RCM Nitroreductase FQU82_02432 ENOG4108TZV Membrane FQU82_02433 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) FQU82_02435 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) FQU82_02436 ENOG4105K8N protein family UPF0079, ATPase FQU82_02443 ENOG4105DZ2 Transcriptional regulator FQU82_02446 ENOG4105F27 Major Facilitator FQU82_02447 ENOG4105EYW Ion transport protein FQU82_02449 ENOG4107QIJ Aconitate hydratase 2 FQU82_02452 ENOG4105CFU surface antigen FQU82_02453 ENOG4107S74 Lysophospholipid transporter LplT FQU82_02456 ENOG4105CFQ glutamine synthetase FQU82_02457 ENOG4105EEX Two component transcriptional regulator (Winged helix family FQU82_02458 ENOG4105C08 Histidine kinase FQU82_02460 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) FQU82_02461 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) FQU82_02466 ENOG4105D06 uba thif-type nad fad binding protein FQU82_02467 ENOG4108MEJ flavin reductase domain protein FQU82_02469 ENOG4105C1G acyl-Coa dehydrogenase FQU82_02470 ENOG4105C1G acyl-Coa dehydrogenase FQU82_02473 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) FQU82_02476 ENOG4105CC0 LysR family Transcriptional regulator FQU82_02479 ENOG4105DEN Luciferase family FQU82_02481 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD FQU82_02482 ENOG4105CND Glycosyl transferase, family 2 FQU82_02483 ENOG4107BJW polysaccharide deacetylase FQU82_02488 ENOG4105E2S oxidase) subunit II FQU82_02489 ENOG4105BZ9 Cytochrome C oxidase, subunit I FQU82_02490 ENOG4105CCU oxidase (Subunit III) FQU82_02491 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) FQU82_02496 ENOG4105CDU Replicative dna helicase FQU82_02497 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FQU82_02507 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) FQU82_02508 ENOG4105DC1 bifunctional purine biosynthesis protein purh FQU82_02509 ENOG4105C12 Phosphoribosylglycinamide synthetase FQU82_02511 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FQU82_02512 ENOG4108UMI ABC transporter, permease FQU82_02513 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) FQU82_02515 ENOG4105CK2 sodium dicarboxylate symporter FQU82_02525 ENOG4105ETX regulatoR FQU82_02526 ENOG4105DHQ Histidine kinase FQU82_02527 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase FQU82_02529 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase FQU82_02537 ENOG4105VT2 5-hydroxyisourate hydrolase FQU82_02539 ENOG4105DY2 Paraquat-inducible protein b FQU82_02540 ENOG4105F1S paraquat-inducible protein a FQU82_02547 ENOG4105CSH Transporter FQU82_02558 ENOG4105JXH GntR family transcriptional regulator FQU82_02560 ENOG4105D6U Sodium Glutamate Symporter FQU82_02566 ENOG4105H4F exported protein FQU82_02573 ENOG4105C26 Dehydrogenase FQU82_02574 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FQU82_02575 ENOG4105EVZ LysR family transcriptional regulator FQU82_02580 ENOG4105D9P serine threonine protein kinase FQU82_02585 ENOG4105VCC 30S ribosomal protein S21 FQU82_02586 ENOG4105KTH gatB Yqey FQU82_02587 ENOG4105ERG peptidase m48, ste24p FQU82_02588 ENOG4105C5I Dehydrogenase FQU82_02591 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase FQU82_02598 ENOG41069NU Nitroreductase FQU82_02600 ENOG4105C1J atp-dependent rna helicase FQU82_02601 ENOG4105VEQ Cold shock protein FQU82_02603 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FQU82_02604 ENOG4105M08 Membrane FQU82_02610 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) FQU82_02611 ENOG4105CIN aminoacyl-histidine dipeptidase FQU82_02613 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase FQU82_02614 ENOG4105CQC Prephenate dehydratase FQU82_02615 ENOG4105NIV Esterase FQU82_02616 ENOG4105C1G acyl-Coa dehydrogenase FQU82_02617 ENOG4105CK2 sodium dicarboxylate symporter FQU82_02618 ENOG4107QYG anthranilate phosphoribosyltransferase FQU82_02619 ENOG4105VUT cytoplasmic protein FQU82_02620 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) FQU82_02621 ENOG4105BZ4 penicillin-binding protein FQU82_02623 ENOG4105M6F mutator MutT protein FQU82_02625 ENOG4105DHQ Histidine kinase FQU82_02626 ENOG4105XJC Two component transcriptional regulator (Winged helix family FQU82_02627 ENOG4108YDI single-species biofilm formation on inanimate substrate FQU82_02628 ENOG4107QHF type ii secretion system protein e FQU82_02630 ENOG4108R96 Methyltransferase, YaeB family FQU82_02631 ENOG4105DP0 ferredoxin-NADP reductase FQU82_02632 ENOG4105JAB phenazine biosynthesis protein, phzf family FQU82_02633 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FQU82_02634 ENOG4105CFP Peptidase U32 FQU82_02635 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding FQU82_02637 ENOG4108JEH abc transporter atp-binding protein FQU82_02638 ENOG4106YG3 ABC transporter FQU82_02639 ENOG4105DSP amino acid AbC transporter FQU82_02640 ENOG4105E89 ABC transporter FQU82_02642 ENOG4105ENT Efflux transporter rnd family, mfp subunit FQU82_02644 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FQU82_02662 ENOG4105XB7 anti-repressor protein FQU82_02701 ENOG4105CDU Replicative dna helicase FQU82_02716 ENOG41076J9 exonuclease VIII FQU82_02722 ENOG4105WXW Antirepressor FQU82_02724 ENOG4105DA5 (ABC) transporter FQU82_02725 ENOG4105E3A (ABC) transporter FQU82_02728 ENOG4105CNI cell division protein FtsW FQU82_02729 ENOG4105CVE Lytic murein transglycosylase FQU82_02737 ENOG4105CE9 30S ribosomal protein S2 FQU82_02738 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FQU82_02740 ENOG4107RNU major facilitator superfamily MFS_1 FQU82_02743 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) FQU82_02744 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) FQU82_02745 ENOG4107QPN acyl-Coa dehydrogenase FQU82_02748 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) FQU82_02749 ENOG4105SYT Methylenetetrahydrofolate reductase FQU82_02750 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) FQU82_02751 ENOG4105BZU Histidine kinase FQU82_02752 ENOG4105C6K Malic enzyme FQU82_02754 ENOG4105C0H protease FQU82_02755 ENOG4107QNR UPF0135 protein FQU82_02756 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FQU82_02763 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) FQU82_02765 ENOG4105C5F glutamine synthetase FQU82_02766 ENOG4105DUX Transporter FQU82_02768 ENOG4105DDQ anthranilate synthase FQU82_02769 ENOG4105CD8 aminopeptidase N FQU82_02775 ENOG4105C7W Xanthine dehydrogenase FQU82_02777 ENOG4105EUJ GTP cyclohydrolase i FQU82_02781 ENOG4105NX3 Membrane FQU82_02784 ENOG4105E4F Isochorismate synthase FQU82_02787 ENOG4108JJ7 ABC transporter FQU82_02788 ENOG4105BZ1 (ABC) transporter FQU82_02791 ENOG4105WQI isochorismatase FQU82_02792 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase FQU82_02793 ENOG4105C0W non-ribosomal peptide synthetase FQU82_02797 ENOG4108IPW abc transporter atp-binding protein FQU82_02801 ENOG4105CEY Amp-dependent synthetase and ligase FQU82_02804 ENOG4105WWK YheO domain protein FQU82_02806 ENOG4105C2I pirin domain protein FQU82_02812 ENOG4105VCD cytoplasmic protein FQU82_02813 ENOG4105D22 carbon starvation protein FQU82_02815 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein FQU82_02817 ENOG41066DG (EAL) domain protein FQU82_02819 ENOG4105DHU Bile acid FQU82_02822 ENOG4105DAN ATP-dependent protease FQU82_02823 ENOG4105EJC lysr family transcriptional regulator FQU82_02824 ENOG4108K5P (LipO)protein FQU82_02828 ENOG4105DZ1 carboxypeptidase FQU82_02829 ENOG4108Z0R Transferase FQU82_02833 ENOG4107QTF adenylosuccinate lyase FQU82_02836 ENOG4105ERU peptidase FQU82_02837 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) FQU82_02839 ENOG4105C8U phosphate abc transporter FQU82_02840 ENOG4105CVA phosphate FQU82_02841 ENOG4105C85 amino acid FQU82_02842 ENOG4107RA9 decarboxylase FQU82_02843 ENOG4105F7P transcriptional regulator AsnC family FQU82_02845 ENOG4105DY8 decarboxylase FQU82_02846 ENOG4108JPW Aminotransferase FQU82_02849 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein FQU82_02851 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FQU82_02854 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) FQU82_02855 ENOG4105D3G Pseudouridine synthase FQU82_02858 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) FQU82_02864 ENOG4105JAB phenazine biosynthesis protein, phzf family FQU82_02865 ENOG4108ETY sodium dicarboxylate symporter FQU82_02866 ENOG4105EGI Transcriptional regulator FQU82_02867 ENOG4105CBP Major Facilitator FQU82_02871 ENOG4108R99 pseudouridine synthase FQU82_02872 ENOG4105E9K Isocitrate dehydrogenase FQU82_02874 ENOG4105DZ1 carboxypeptidase FQU82_02875 ENOG4105CEP NADH dehydrogenase FQU82_02876 ENOG4108YZY peptidylprolyl cis-trans isomerase FQU82_02877 ENOG4105CVP deoxyribo-dipyrimidine photolyase FQU82_02880 ENOG4107R8N Glycosyl transferase, family 2 FQU82_02886 ENOG4105EA8 2-Nitropropane dioxygenase FQU82_02887 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FQU82_02888 ENOG4107QS8 (LipO)protein FQU82_02895 ENOG4105DTR rard protein FQU82_02897 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) FQU82_02899 ENOG4105BZU Histidine kinase FQU82_02903 ENOG4105F7F Chaperone FQU82_02908 ENOG4105EMU Dehydrogenase FQU82_02909 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase FQU82_02910 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) FQU82_02911 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) FQU82_02913 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) FQU82_02916 ENOG4105C3F Signal peptidase i FQU82_02919 ENOG4105C0H protease FQU82_02920 ENOG4108IYU L-aspartate oxidase FQU82_02923 ENOG4105HHA aminodeoxychorismate lyase FQU82_02924 ENOG4105YAZ 4-amino-4-deoxychorismate lyase FQU82_02925 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein FQU82_02927 ENOG4108I5D sulfate abc transporter FQU82_02929 ENOG4108IJ6 ABC transporter FQU82_02930 ENOG4107R11 Transcriptional regulator FQU82_02933 ENOG4107VRB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) FQU82_02934 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) FQU82_02937 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FQU82_02940 ENOG4108UKI Enoyl-CoA hydratase FQU82_02941 ENOG4105EGD dinuclear metal center protein, YbgI family FQU82_02943 ENOG4105C2C drug resistance transporter, Bcr CflA FQU82_02944 ENOG4108ETH Formylglycinamide ribotide synthetase FQU82_02948 ENOG4105CH2 amidohydrolase FQU82_02949 ENOG4107YD3 Thioesterase FQU82_02950 ENOG4105E02 MotA TolQ exbB proton channel FQU82_02951 ENOG4105M8F Biopolymer transport protein exbD tolR FQU82_02953 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) FQU82_02954 ENOG4105KCK Peptidoglycan-associated lipoprotein FQU82_02964 ENOG4105C02 permease FQU82_02966 ENOG4108V3E phosphoribosylglycinamide formyltransferase FQU82_02967 ENOG4107R6F Alpha Beta Hydrolase Fold protein FQU82_02968 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) FQU82_02970 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 FQU82_02971 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FQU82_02972 ENOG4105D60 lipoprotein releasing system transmembrane protein FQU82_02979 ENOG4107KET secretion protein, HlyD family FQU82_02986 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FQU82_02987 ENOG4105C10 Electron transfer flavoprotein FQU82_02988 ENOG4105BZJ Electron transfer flavoprotein FQU82_02989 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FQU82_02990 ENOG4105N14 lysine exporter protein LysE YggA FQU82_02991 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) FQU82_02994 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) FQU82_02996 ENOG4105C85 amino acid FQU82_02997 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) FQU82_02999 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) FQU82_03002 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) FQU82_03003 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit FQU82_03004 ENOG4105BZW Glycerate kinase FQU82_03012 ENOG4105CEY Amp-dependent synthetase and ligase FQU82_03015 ENOG4108RRZ Transcription elongation factor GreB FQU82_03019 ENOG4105E4C Lytic transglycosylase catalytic FQU82_03022 ENOG4105BZS acriflavin resistance protein FQU82_03023 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase FQU82_03025 ENOG41080IJ Diacylglycerol kinase FQU82_03029 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) FQU82_03032 ENOG4105C6V Glycerol-3-phosphate dehydrogenase FQU82_03033 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) FQU82_03034 ENOG4105CSH Transporter FQU82_03044 ENOG4105EEI dihydropteroate synthase FQU82_03045 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FQU82_03047 ENOG4105HBR Rna-binding protein FQU82_03050 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain FQU82_03051 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain FQU82_03054 ENOG41080TK Universal stress protein FQU82_03057 ENOG4105PNM synthesis protein FQU82_03060 ENOG4105EEQ Na H antiporter FQU82_03061 ENOG4105CGZ zinc metallopeptidase FQU82_03062 ENOG4105CKW Inner membrane protein yedI FQU82_03064 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha FQU82_03066 ENOG4107QN2 dihydrolipoyl dehydrogenase FQU82_03067 ENOG4105C7S Dehydrogenase FQU82_03068 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 FQU82_03069 ENOG4105E33 succinate dehydrogenase FQU82_03071 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein FQU82_03072 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit FQU82_03078 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FQU82_03079 ENOG41084BA UPF0250 protein FQU82_03080 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) FQU82_03083 ENOG4105CUB amino acid FQU82_03086 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) FQU82_03087 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) FQU82_03090 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) FQU82_03095 ENOG410841Q phosphoesterase PA-phosphatase related protein FQU82_03096 ENOG4105C1P efflux transporter, rnd family, mfp subunit FQU82_03097 ENOG4105BZS acriflavin resistance protein FQU82_03098 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FQU82_03099 ENOG4105K8R UPF0145 protein FQU82_03100 ENOG4105K8R UPF0145 protein FQU82_03104 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) FQU82_03108 ENOG4108M0I Transcriptional regulator FQU82_03111 ENOG4105DHQ Histidine kinase FQU82_03112 ENOG4105XJC Two component transcriptional regulator (Winged helix family FQU82_03113 ENOG4105DIJ Phosphoethanolamine transferase FQU82_03117 ENOG4105D78 K07001 NTE family protein FQU82_03120 ENOG4105MSB protein, conserved in bacteria FQU82_03121 ENOG4105CTB Polyprenyl synthetase FQU82_03122 ENOG4105C7F AcnD-accessory protein PrpF FQU82_03123 ENOG4105C85 amino acid FQU82_03127 ENOG4105CF7 AraC family transcriptional regulator FQU82_03132 ENOG4108X0B nad(p)h dehydrogenase (quinone) FQU82_03134 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein FQU82_03136 ENOG4105D8T Acyltransferase FQU82_03138 ENOG4105C03 ribonuclease FQU82_03139 ENOG4108Z03 MAF-like protein FQU82_03140 ENOG4105VQ7 Rod shape-determining protein MreD FQU82_03141 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) FQU82_03142 ENOG4105DFF Rod shape-determining protein mreb FQU82_03143 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) FQU82_03145 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) FQU82_03151 ENOG4105C7B Threonine dehydratase FQU82_03152 ENOG4105D78 K07001 NTE family protein FQU82_03153 ENOG4105BZG amino acid carrier protein FQU82_03156 ENOG4105C2C drug resistance transporter, Bcr CflA FQU82_03157 ENOG4105EM2 membrane FQU82_03159 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) FQU82_03167 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FQU82_03168 ENOG4105WD1 Membrane FQU82_03170 ENOG4106HKS Entericidin EcnA/B family FQU82_03173 ENOG4105CBS Chea signal transduction histidine kinase FQU82_03174 ENOG4105C8Q Methyl-accepting chemotaxis FQU82_03175 ENOG4108ZGA chew protein FQU82_03176 ENOG4105M3Z response regulator FQU82_03177 ENOG4108UNF response regulator FQU82_03182 ENOG4105KWI UPF0339 protein FQU82_03183 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA FQU82_03184 ENOG4105K78 MarR family Transcriptional regulator FQU82_03186 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) FQU82_03187 ENOG4105T95 Thiol disulfide interChange protein FQU82_03190 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FQU82_03191 ENOG4105CHB tonB-dependent Receptor FQU82_03192 ENOG4108VX5 3-methyladenine DNA glycosylase FQU82_03194 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FQU82_03198 ENOG4105C2W permease FQU82_03200 ENOG4108IQI permease FQU82_03201 ENOG4105E0Y RtcB Protein FQU82_03203 ENOG4108WHA ompa motb domain protein FQU82_03205 ENOG4105CHU acetyl-coa acetyltransferase FQU82_03209 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) FQU82_03210 ENOG4105DZG Dehydrogenase FQU82_03211 ENOG4105TW1 Carbohydrate-selective porin OprB FQU82_03213 ENOG4108R6W Transcriptional regulator, ARAC family FQU82_03214 ENOG4105CHU acetyl-coa acetyltransferase FQU82_03220 ENOG4108UT2 hemolysin iii FQU82_03221 ENOG4105CSH Transporter FQU82_03224 ENOG4105D3R alkyl hydroperoxide reductase FQU82_03228 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase FQU82_03235 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) FQU82_03237 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) FQU82_03238 ENOG4108WBT adenosyltransferase FQU82_03242 ENOG4105CNG UPF0061 protein FQU82_03243 ENOG4105E3W Two component transcriptional regulator (Winged helix family FQU82_03244 ENOG4105EB3 Histidine kinase FQU82_03246 ENOG4105CSU acyl-Coa dehydrogenase FQU82_03247 ENOG4105CSU acyl-Coa dehydrogenase FQU82_03248 ENOG4108R4R Iron-regulated virulence regulatory protein FQU82_03249 ENOG4108K3A Glutathione S-transferase FQU82_03250 ENOG4108VY7 phosphate-starvation-inducible protein PsiE FQU82_03254 ENOG4105UGU tonB-dependent Receptor FQU82_03262 ENOG4108PQP glycosyl transferase group 1 FQU82_03264 ENOG4107BJW polysaccharide deacetylase FQU82_03267 ENOG4105CM2 brancheD-chain amino acid aminotransferase FQU82_03268 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) FQU82_03269 ENOG4105BZU Histidine kinase FQU82_03276 ENOG4105VIE preprotein translocase, subunit YajC FQU82_03277 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FQU82_03278 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FQU82_03279 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase FQU82_03281 ENOG4105FFC UPF0187 protein FQU82_03282 ENOG4105DB7 PHP domain protein FQU82_03284 ENOG4105K9H YciI-like protein FQU82_03290 ENOG4105NAU thioesterase Superfamily protein FQU82_03292 ENOG4107U2T alpha beta FQU82_03293 ENOG4107QPB Beta-lactamase domain protein FQU82_03295 ENOG4107QN2 dihydrolipoyl dehydrogenase FQU82_03302 ENOG4108KHX Diguanylate cyclase FQU82_03303 ENOG4105UYK outer membrane protein a FQU82_03305 ENOG4107RZC phospholipase d FQU82_03307 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FQU82_03311 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) FQU82_03312 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) FQU82_03313 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) FQU82_03315 ENOG4108UJD 30S ribosomal protein S9 FQU82_03316 ENOG4107MKT Stringent starvation protein a FQU82_03317 ENOG4105KB2 stringent starvation protein b FQU82_03321 ENOG4105C1G acyl-Coa dehydrogenase FQU82_03322 ENOG4107QX3 carboxylase FQU82_03325 ENOG4108RZE Tetr family transcriptional regulator FQU82_03326 ENOG4105C1G acyl-Coa dehydrogenase FQU82_03335 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase FQU82_03336 ENOG4105D6S protein involved in catabolism of external DNA FQU82_03342 ENOG4105E4C Lytic transglycosylase catalytic FQU82_03344 ENOG4105C9A Phoh family FQU82_03350 ENOG4105CS1 NAD(P)H quinone oxidoreductase FQU82_03351 ENOG4107S2Z UPF0761 membrane protein FQU82_03353 ENOG4108K2B transcriptional regulator FQU82_03354 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase FQU82_03363 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) FQU82_03364 ENOG4105DGW oligopeptidase A FQU82_03365 ENOG4105VKU nucleicacid-binding protein FQU82_03373 ENOG4105C1G acyl-Coa dehydrogenase FQU82_03378 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) FQU82_03380 ENOG41067V7 50S ribosomal protein L36 FQU82_03381 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FQU82_03403 ENOG41089BK Glutamine amido-transferase FQU82_03404 ENOG4105C28 cystathionine FQU82_03405 ENOG4105D7A ATP-binding protein FQU82_03407 ENOG4105KPV Transcriptional regulator FQU82_03410 ENOG4105CK2 sodium dicarboxylate symporter FQU82_03411 ENOG4105C29 acyl-CoA thioesterase FQU82_03415 ENOG4105CB5 ATP-dependent DNA helicase recG FQU82_03416 ENOG4105MJ2 Competence protein FQU82_03418 ENOG4108URH decarboxylase FQU82_03419 ENOG4105D7N magnesium and cobalt transport protein CorA FQU82_03421 ENOG4105E3I toluene tolerance FQU82_03423 ENOG4105CY3 ABC transporter, permease FQU82_03424 ENOG4105DHJ ABC, transporter FQU82_03425 ENOG4105C1J atp-dependent rna helicase FQU82_03426 ENOG4105ECY inositol monophosphatase FQU82_03429 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) FQU82_03432 ENOG4105CSU acyl-Coa dehydrogenase FQU82_03434 ENOG41067S9 phage shock protein C, PspC FQU82_03435 ENOG4105W87 Cbs domain FQU82_03446 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin FQU82_03451 ENOG4105C26 Dehydrogenase FQU82_03453 ENOG4105C8Y Acetylornithine aminotransferase FQU82_03454 ENOG4105D82 Glutamate dehydrogenase FQU82_03455 ENOG4108IQI permease FQU82_03462 ENOG4105IPI Membrane FQU82_03463 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FQU82_03464 ENOG4105EM2 membrane FQU82_03465 ENOG4107QF7 multi-drug FQU82_03467 ENOG4105NF4 modulator of drug activity FQU82_03468 ENOG4105VRH Antibiotic biosynthesis monooxygenase FQU82_03470 ENOG4105CQB FAD linked oxidase domain protein FQU82_03471 ENOG4108JQ1 Dehydrogenase FQU82_03476 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) FQU82_03477 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) FQU82_03478 ENOG4107IFA Lipase (EC 3.1.1.3) FQU82_03481 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) FQU82_03491 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) FQU82_03493 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FQU82_03494 ENOG4105KME endoribonuclease L-psp FQU82_03496 ENOG4108UQY Iron-storage protein FQU82_03497 ENOG4108YSG O-Antigen polymerase FQU82_03501 ENOG4105HA9 of methanol dehydrogenase type FQU82_03502 ENOG4108V0P LemA family FQU82_03504 ENOG4105BZ8 glutamate synthase FQU82_03505 ENOG4105CBC glutamate synthase FQU82_03509 ENOG4105E4G Type IV pilus FQU82_03515 ENOG4108JQC penicillin-binding protein 1A FQU82_03516 ENOG4105DHI Methyltransferase FQU82_03519 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) FQU82_03520 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FQU82_03521 ENOG4105CJN penicillin-binding protein FQU82_03524 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein FQU82_03529 ENOG4108IQI permease FQU82_03542 ENOG4105C5H ABC transporter FQU82_03544 ENOG4105PDP Short chain dehydrogenase FQU82_03545 ENOG4105CHH sulfate transporter FQU82_03547 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FQU82_03548 ENOG4105E0F Histidine kinase FQU82_03549 ENOG4105CYC Transferase FQU82_03555 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) FQU82_03563 ENOG4105CUV Homoserine Kinase FQU82_03577 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein FQU82_03578 ENOG4105KVH Transcriptional regulator FQU82_03583 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) FQU82_03584 ENOG4105CPC Aldo Keto reductase FQU82_03588 ENOG4106NZI LysR family Transcriptional regulator FQU82_03589 ENOG4105D94 Major Facilitator Superfamily FQU82_03595 ENOG4105EUB pirin domain protein FQU82_03596 ENOG4105CHJ isochorismatase hydrolase FQU82_03598 ENOG4105C26 Dehydrogenase FQU82_03599 ENOG4108JPW Aminotransferase FQU82_03601 ENOG4105C85 amino acid FQU82_03603 ENOG4108UMN azlc family FQU82_03613 ENOG4108UUM single-stranded DNA-binding protein FQU82_03614 ENOG4107RDB Major Facilitator FQU82_03616 ENOG4105DWF phosphomethylpyrimidine kinase FQU82_03617 ENOG4105RA2 Membrane FQU82_03619 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein FQU82_03620 ENOG4108WUH Transcriptional regulator, TetR family FQU82_03621 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FQU82_03622 ENOG4105BZU Histidine kinase FQU82_03624 ENOG4105C94 Transporter FQU82_03626 ENOG4107QN1 sodium solute FQU82_03627 ENOG41062QD Membrane FQU82_03628 ENOG4105BZU Histidine kinase FQU82_03631 ENOG4108UZX fmn reductase FQU82_03632 ENOG4105FBW Monooxygenase FQU82_03634 ENOG4108W2Y isochorismatase FQU82_03635 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FQU82_03638 ENOG4105D64 Mechanosensitive ion channel FQU82_03640 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase FQU82_03641 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FQU82_03643 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) FQU82_03645 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) FQU82_03648 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FQU82_03651 ENOG4105E0K tonB-dependent siderophore receptor FQU82_03654 ENOG4107QSN dihydrolipoamide acetyltransferase FQU82_03655 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) FQU82_03656 ENOG41063SB peptidase FQU82_03659 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) FQU82_03660 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) FQU82_03661 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) FQU82_03665 ENOG4105D7Z glutathione synthase FQU82_03669 ENOG4105CGK Exodeoxyribonuclease III FQU82_03670 ENOG4105KUZ arsenate reductase FQU82_03673 ENOG4105BZU Histidine kinase FQU82_03674 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) FQU82_03680 ENOG41084YZ Hydrolase FQU82_03683 ENOG41061H0 Monooxygenase FQU82_03685 ENOG4108Z2U ureidoglycolate hydrolase FQU82_03686 ENOG4105EWI Short-chain dehydrogenase reductase Sdr FQU82_03687 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FQU82_03688 ENOG4105IPS esterase FQU82_03691 ENOG4105NVB glycoside hydrolase, family 19 FQU82_03692 ENOG4105CS6 Rhs element vgr protein FQU82_03694 ENOG4105D9M gamma-glutamylcysteine synthetase FQU82_03697 ENOG4106BRA Membrane FQU82_03698 ENOG4105CHM Aminotransferase FQU82_03699 ENOG4107QJQ Mate efflux family protein FQU82_03702 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FQU82_03703 ENOG4105BZU Histidine kinase FQU82_03706 ENOG4105KHC sulfurtransferase FQU82_03715 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) FQU82_03718 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) FQU82_03719 ENOG4108ZAI phosphatidylglycerophosphatase a FQU82_03721 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) FQU82_03722 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) FQU82_03723 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 FQU82_03725 ENOG41088SP formiminoglutamate hydrolase FQU82_03727 ENOG4105C85 amino acid FQU82_03730 ENOG41090B9 response to stress FQU82_03731 ENOG4105CZE histidine utilization repressor FQU82_03733 ENOG4105CKI cobalamin synthesis protein FQU82_03735 ENOG4105C85 amino acid FQU82_03737 ENOG4108RXX maleylacetoacetate isomerase FQU82_03741 ENOG4105EWC Purine nucleoside phosphorylase FQU82_03743 ENOG4107QI1 Mate efflux family protein FQU82_03744 ENOG4105C09 Bile acid FQU82_03745 ENOG4108RWI nicotinamidase FQU82_03746 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FQU82_03750 ENOG4105S64 Formate nitrite transporter FQU82_03751 ENOG4105D1H recombination factor protein RarA FQU82_03753 ENOG4108ZZ3 UPF0260 protein FQU82_03757 ENOG4105CEN a g-specific adenine glycosylase FQU82_03760 ENOG4108R3E Dna-3-methyladenine glycosylase i FQU82_03761 ENOG4105DQ4 alcohol dehydrogenase FQU82_03764 ENOG4105HEI LysR family (Transcriptional regulator FQU82_03765 ENOG4105CV8 reductase FQU82_03766 ENOG4105F27 Major Facilitator FQU82_03773 ENOG4105DJY efflux transporter, rnd family, mfp subunit FQU82_03774 ENOG4108IG5 Transcriptional regulator FQU82_03776 ENOG4105C2W permease FQU82_03777 ENOG4108W5M transcriptional regulator FQU82_03782 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B FQU82_03784 ENOG4105C8J )-transporter FQU82_03786 ENOG4107MKT Stringent starvation protein a FQU82_p200004 ENOG4105XUP Phage derived protein Gp49-like (DUF891) FQU82_p200009 ENOG4108ZHJ Organic hydroperoxide resistance protein FQU82_p200010 ENOG4105K56 Transcriptional regulator