locus-tag	class	description
HIN89_00010	COG0592	DNA-directed DNA polymerase activity
HIN89_00020	COG0187	DNA topoisomerase II activity
HIN89_00030	COG0586	Pfam SNARE associated Golgi protein
HIN89_00035	COG0488	(ABC) transporter
HIN89_00060	COG0596	Alpha beta hydrolase
HIN89_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HIN89_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HIN89_00110	COG1047	Peptidyl-prolyl cis-trans
HIN89_00120	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HIN89_00125	COG0196	riboflavin kinase activity
HIN89_00135	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HIN89_00140	COG1309	transcriptional regulator
HIN89_00145	COG1116	anion transmembrane transporter activity
HIN89_00150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HIN89_00155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HIN89_00160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HIN89_00165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HIN89_00185	COG1028	Short-chain dehydrogenase reductase Sdr
HIN89_00190	COG0546	phosphoglycolate phosphatase activity
HIN89_00250	COG3023	N-Acetylmuramoyl-L-alanine amidase
HIN89_00255	COG0728	peptidoglycan biosynthetic process
HIN89_00280	COG1596	polysaccharide export
HIN89_00285	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HIN89_00295	COG1215	transferase activity, transferring glycosyl groups
HIN89_00300	COG0438	transferase activity, transferring glycosyl groups
HIN89_00320	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HIN89_00325	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HIN89_00340	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HIN89_00350	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HIN89_00360	COG2186	Transcriptional regulator
HIN89_00370	COG0277	FAD linked oxidase domain protein
HIN89_00375	COG1448	Aminotransferase
HIN89_00385	COG1802	Transcriptional regulator
HIN89_00400	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HIN89_00410	COG3293	Transposase
HIN89_00430	COG1051	belongs to the nudix hydrolase family
HIN89_00455	COG0564	pseudouridine synthase activity
HIN89_00495	COG0251	oxidation-reduction process
HIN89_00500	COG1113	amino acid transport
HIN89_00505	COG1113	amino acid transport
HIN89_00525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HIN89_00530	COG1960	acyl-CoA dehydrogenase activity
HIN89_00535	COG1024	Enoyl-CoA hydratase
HIN89_00540	COG1024	Enoyl-CoA hydratase
HIN89_00555	COG2267	carboxylic ester hydrolase activity
HIN89_00575	COG0271	Belongs to the BolA IbaG family
HIN89_00585	COG1192	Involved in chromosome partitioning
HIN89_00600	COG0586	Pfam SNARE associated Golgi protein
HIN89_00605	COG2259	Doxx family
HIN89_00610	COG4399	Belongs to the UPF0754 family
HIN89_00615	COG0519	Catalyzes the synthesis of GMP from XMP
HIN89_00615	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HIN89_00660	COG0281	malic enzyme
HIN89_00665	COG2837	iron assimilation
HIN89_00670	COG1280	lysine exporter protein (LysE YggA)
HIN89_00675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HIN89_00680	COG1121	(ABC) transporter
HIN89_00745	COG0386	Belongs to the glutathione peroxidase family
HIN89_00760	COG1309	transcriptional regulator
HIN89_00765	COG0697	spore germination
HIN89_00775	COG0758	DNA mediated transformation
HIN89_00845	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HIN89_00855	COG0655	NAD(P)H dehydrogenase (quinone) activity
HIN89_00895	COG4452	Inner membrane protein CreD
HIN89_00900	COG2205	protein histidine kinase activity
HIN89_00905	COG0745	RESPONSE REGULATOR receiver
HIN89_00910	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HIN89_00920	COG2814	Major facilitator Superfamily
HIN89_00930	COG1253	flavin adenine dinucleotide binding
HIN89_00935	COG3012	SEC-C Motif Domain Protein
HIN89_00940	COG2860	membrane
HIN89_00945	COG0477	Major facilitator Superfamily
HIN89_00955	COG0318	PFAM AMP-dependent synthetase and ligase
HIN89_00970	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HIN89_00985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HIN89_00990	COG0235	Class ii aldolase
HIN89_00995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HIN89_01000	COG0606	chelatase, subunit chli
HIN89_01010	COG0347	Belongs to the P(II) protein family
HIN89_01015	COG0004	ammonium transporteR
HIN89_01025	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HIN89_01025	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HIN89_01065	COG0795	lipopolysaccharide-transporting ATPase activity
HIN89_01070	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HIN89_01075	COG0793	Belongs to the peptidase S41A family
HIN89_01090	COG2197	response regulator
HIN89_01100	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HIN89_01110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HIN89_01115	COG4974	Belongs to the 'phage' integrase family
HIN89_01140	COG0772	Belongs to the SEDS family
HIN89_01145	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HIN89_01150	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HIN89_01155	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HIN89_01195	COG1538	Outer membrane efflux protein
HIN89_01215	COG3275	phosphorelay sensor kinase activity
HIN89_01225	COG0181	hydroxymethylbilane synthase activity
HIN89_01270	COG1716	ATPase activity
HIN89_01275	COG0546	phosphoglycolate phosphatase activity
HIN89_01370	COG0596	Alpha beta hydrolase
HIN89_01375	COG2056	Na+-H+ antiporter family
HIN89_01390	COG0326	Molecular chaperone. Has ATPase activity
HIN89_01405	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HIN89_01475	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HIN89_01480	COG2169	Transcriptional regulator
HIN89_01480	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HIN89_01510	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HIN89_01520	COG0497	DNA recombination
HIN89_01535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HIN89_01545	COG0237	dephospho-CoA kinase activity
HIN89_01595	COG0195	Participates in both transcription termination and antitermination
HIN89_01615	COG2212	antiporter activity
HIN89_01625	COG0651	ATP synthesis coupled electron transport
HIN89_01630	COG1006	Multisubunit Na H antiporter MnhC subunit
HIN89_01635	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HIN89_01635	COG2111	Na H antiporter
HIN89_01650	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HIN89_01670	COG2226	methyltransferase
HIN89_01690	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HIN89_01695	COG1074	ATP-dependent DNA helicase activity
HIN89_01700	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HIN89_01720	COG0598	Magnesium transport protein CorA
HIN89_01725	COG0789	Transcriptional regulator
HIN89_01730	COG0484	heat shock protein binding
HIN89_01745	COG0475	glutathione-regulated potassium exporter activity
HIN89_01745	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HIN89_01750	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HIN89_01770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HIN89_01780	COG4535	Mg2 and Co2 transporter CorC
HIN89_01785	COG0425	Belongs to the sulfur carrier protein TusA family
HIN89_01795	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HIN89_01795	COG0644	oxidoreductase
HIN89_01805	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HIN89_01820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HIN89_01825	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HIN89_01865	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HIN89_01880	COG0534	Mate efflux family protein
HIN89_01890	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HIN89_01895	COG4221	oxidoreductase activity
HIN89_01900	COG0583	DNA-binding transcription factor activity
HIN89_01915	COG0318	PFAM AMP-dependent synthetase and ligase
HIN89_01920	COG1530	ribonuclease E activity
HIN89_01935	COG0546	phosphoglycolate phosphatase activity
HIN89_01940	COG2378	regulation of single-species biofilm formation
HIN89_01955	COG0583	DNA-binding transcription factor activity
HIN89_01985	COG0583	DNA-binding transcription factor activity
HIN89_02010	COG0473	3-isopropylmalate dehydrogenase activity
HIN89_02065	COG1301	dicarboxylic acid transport
HIN89_02075	COG1560	Kdo2-lipid A biosynthetic process
HIN89_02080	COG1280	lysine exporter protein (LysE YggA)
HIN89_02095	COG2900	Belongs to the SlyX family
HIN89_02105	COG1733	regulation of RNA biosynthetic process
HIN89_02130	COG0210	DNA helicase
HIN89_02135	COG0724	RNA recognition motif
HIN89_02155	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HIN89_02155	COG4651	solute:proton antiporter activity
HIN89_02180	COG0788	formyltetrahydrofolate deformylase activity
HIN89_02280	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HIN89_02280	COG2813	Specifically methylates the guanine in position
HIN89_02290	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HIN89_02300	COG4774	siderophore transport
HIN89_02310	COG0740	serine-type endopeptidase activity
HIN89_02330	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HIN89_02330	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HIN89_02335	COG0857	belongs to the CobB CobQ family
HIN89_02335	COG0280	phosphate acetyltransferase
HIN89_02340	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HIN89_02350	COG0800	Aldolase
HIN89_02360	COG3265	gluconokinase activity
HIN89_02365	COG1012	belongs to the aldehyde dehydrogenase family
HIN89_02390	COG0793	Belongs to the peptidase S41A family
HIN89_02425	COG1426	Protein conserved in bacteria
HIN89_02465	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HIN89_02475	COG1162	GTPase activity
HIN89_02480	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HIN89_02495	COG1538	Outer membrane efflux protein
HIN89_02500	COG0577	efflux transmembrane transporter activity
HIN89_02500	COG1136	(ABC) transporter
HIN89_02505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HIN89_02530	COG0028	Belongs to the TPP enzyme family
HIN89_02535	COG0440	acetolactate synthase activity
HIN89_02565	COG3501	Rhs element vgr protein
HIN89_02570	COG0484	heat shock protein binding
HIN89_02715	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HIN89_02730	COG0084	hydrolase, TatD family'
HIN89_02740	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HIN89_02750	COG0583	DNA-binding transcription factor activity
HIN89_02760	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HIN89_02845	COG2205	protein histidine kinase activity
HIN89_02860	COG2132	Multicopper oxidase
HIN89_02885	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HIN89_02920	COG0640	Transcriptional regulator
HIN89_02930	COG0798	PFAM Bile acid sodium symporter
HIN89_02935	COG0431	NADPH-dependent FMN reductase
HIN89_02940	COG0492	ferredoxin-NADP+ reductase activity
HIN89_02945	COG2072	flavoprotein involved in K transport
HIN89_02970	COG2814	Major facilitator Superfamily
HIN89_02980	COG0697	spore germination
HIN89_03010	COG3622	Belongs to the hyi family
HIN89_03015	COG2084	Dehydrogenase
HIN89_03020	COG1024	Enoyl-CoA hydratase
HIN89_03025	COG5002	protein histidine kinase activity
HIN89_03025	COG2205	protein histidine kinase activity
HIN89_03025	COG0784	Response regulator, receiver
HIN89_03045	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HIN89_03055	COG3956	TIGRFAM MazG family protein
HIN89_03060	COG1555	photosystem II stabilization
HIN89_03065	COG0617	tRNA 3'-terminal CCA addition
HIN89_03070	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HIN89_03090	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HIN89_03095	COG3028	Belongs to the UPF0307 family
HIN89_03100	COG0318	PFAM AMP-dependent synthetase and ligase
HIN89_03115	COG0625	glutathione transferase activity
HIN89_03120	COG1238	metal cluster binding
HIN89_03160	COG0072	phenylalanine-tRNA ligase activity
HIN89_03190	COG0248	Ppx GppA phosphatase
HIN89_03200	COG0037	tRNA processing
HIN89_03240	COG1764	response to oxidative stress
HIN89_03245	COG1846	Transcriptional regulator
HIN89_03255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HIN89_03315	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HIN89_03320	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HIN89_03325	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HIN89_03335	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HIN89_03370	COG1214	PFAM Peptidase M22, glycoprotease
HIN89_03395	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HIN89_03400	COG0561	phosphatase activity
HIN89_03410	COG2132	Multicopper oxidase
HIN89_03415	COG3667	copper resistance
HIN89_03430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HIN89_03435	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HIN89_03440	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HIN89_03470	COG1063	alcohol dehydrogenase
HIN89_03475	COG0583	DNA-binding transcription factor activity
HIN89_03480	COG1960	acyl-CoA dehydrogenase activity
HIN89_03485	COG2814	Major facilitator Superfamily
HIN89_03490	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HIN89_03495	COG1309	transcriptional regulator
HIN89_03510	COG1053	succinate dehydrogenase
HIN89_03515	COG0583	DNA-binding transcription factor activity
HIN89_03530	COG0583	DNA-binding transcription factor activity
HIN89_03540	COG0583	DNA-binding transcription factor activity
HIN89_03555	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HIN89_03570	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HIN89_03590	COG0745	RESPONSE REGULATOR receiver
HIN89_03595	COG2205	protein histidine kinase activity
HIN89_03630	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HIN89_03660	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HIN89_03665	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HIN89_03685	COG0583	DNA-binding transcription factor activity
HIN89_03705	COG0668	transmembrane transport
HIN89_03715	COG2081	HI0933 family
HIN89_03720	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HIN89_03750	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HIN89_03750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HIN89_03760	COG0489	protein tyrosine kinase activity
HIN89_03810	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HIN89_03820	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HIN89_03835	COG0730	response to heat
HIN89_03845	COG1196	nuclear chromosome segregation
HIN89_03865	COG2223	nitrite transmembrane transporter activity
HIN89_03870	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HIN89_03875	COG1877	trehalose-phosphatase activity
HIN89_03880	COG0596	Alpha beta hydrolase
HIN89_03880	COG2226	methyltransferase
HIN89_03880	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HIN89_03895	COG4106	trans-aconitate 2-methyltransferase activity
HIN89_03910	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HIN89_03915	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HIN89_03920	COG0009	L-threonylcarbamoyladenylate synthase
HIN89_03925	COG3101	peptidyl-lysine hydroxylation
HIN89_03930	COG1399	metal-binding, possibly nucleic acid-binding protein
HIN89_03955	COG1652	LysM domain
HIN89_03960	COG0352	thiamine-phosphate diphosphorylase activity
HIN89_03960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HIN89_03960	COG0351	phosphomethylpyrimidine kinase
HIN89_03970	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HIN89_04000	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HIN89_04030	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HIN89_04045	COG0358	DNA primase activity
HIN89_04055	COG0564	pseudouridine synthase activity
HIN89_04080	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HIN89_04100	COG0583	DNA-binding transcription factor activity
HIN89_04105	COG0473	3-isopropylmalate dehydrogenase activity
HIN89_04125	COG1012	belongs to the aldehyde dehydrogenase family
HIN89_04145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HIN89_04145	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HIN89_04205	COG0456	acetyltransferase
HIN89_04215	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HIN89_04220	COG0492	ferredoxin-NADP+ reductase activity
HIN89_04225	COG1674	ftsk spoiiie
HIN89_04225	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HIN89_04230	COG1280	lysine exporter protein (LysE YggA)
HIN89_04245	COG2894	cell division
HIN89_04260	COG0204	Acyl-transferase
HIN89_04265	COG2885	chlorophyll binding
HIN89_04270	COG0210	DNA helicase
HIN89_04280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HIN89_04295	COG0121	glutamine amidotransferase
HIN89_04315	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HIN89_04320	COG0735	belongs to the Fur family
HIN89_04345	COG0420	3'-5' exonuclease activity
HIN89_04365	COG1090	epimerase
HIN89_04380	COG2050	protein possibly involved in aromatic compounds catabolism
HIN89_04390	COG2814	Major facilitator Superfamily
HIN89_04395	COG0405	Gamma-glutamyltransferase
HIN89_04405	COG0582	viral genome integration into host DNA
HIN89_04510	COG0531	amino acid
HIN89_04515	COG2040	homocysteine
HIN89_04540	COG1309	transcriptional regulator
HIN89_04545	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HIN89_04550	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HIN89_04560	COG1607	acyl-coa hydrolase
HIN89_04570	COG0523	cobalamin synthesis protein
HIN89_04580	COG4681	YaeQ
HIN89_04590	COG0726	polysaccharide deacetylase
HIN89_04590	COG1649	PFAM Uncharacterised BCR, COG1649
HIN89_04595	COG1215	transferase activity, transferring glycosyl groups
HIN89_04605	COG1024	Enoyl-CoA hydratase
HIN89_04620	COG1414	Transcriptional regulator
HIN89_04640	COG1028	Short-chain dehydrogenase reductase Sdr
HIN89_04655	COG2271	Major facilitator Superfamily
HIN89_04665	COG2267	carboxylic ester hydrolase activity
HIN89_04670	COG1028	Short-chain dehydrogenase reductase Sdr
HIN89_04685	COG0028	Belongs to the TPP enzyme family
HIN89_04695	COG0477	Major facilitator Superfamily
HIN89_04700	COG0242	peptide deformylase activity
HIN89_04705	COG2066	Belongs to the glutaminase family
HIN89_04710	COG2207	Transcriptional regulator
HIN89_04715	COG2223	nitrite transmembrane transporter activity
HIN89_04730	COG0583	DNA-binding transcription factor activity
HIN89_04735	COG1028	Short-chain dehydrogenase reductase Sdr
HIN89_04740	COG2271	Major facilitator Superfamily
HIN89_04745	COG3959	Transketolase, thiamine diphosphate binding domain
HIN89_04750	COG3958	Transketolase
HIN89_04765	COG0306	phosphate transporter
HIN89_04785	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HIN89_04830	COG4181	ATPase activity
HIN89_04835	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HIN89_04865	COG0583	DNA-binding transcription factor activity
HIN89_04875	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HIN89_04880	COG1773	rubredoxin
HIN89_04930	COG2851	Citrate transporter
HIN89_04935	COG1253	flavin adenine dinucleotide binding
HIN89_04975	COG0804	urea catabolic process
HIN89_04985	COG0830	nickel cation binding
HIN89_05005	COG0742	ribosomal rna small subunit methyltransferase
HIN89_05010	COG0768	penicillin binding
HIN89_05035	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HIN89_05040	COG2878	Part of a membrane complex involved in electron transport
HIN89_05045	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HIN89_05055	COG3384	dioxygenase
HIN89_05080	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HIN89_05120	COG0006	proline dipeptidase activity
HIN89_05125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HIN89_05130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HIN89_05150	COG1279	arginine transmembrane transporter activity
HIN89_05155	COG0583	DNA-binding transcription factor activity
HIN89_05195	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HIN89_05200	COG1388	LysM domain
HIN89_05200	COG0741	lytic transglycosylase activity
HIN89_05200	COG1388	LysM domain
HIN89_05200	COG0741	lytic transglycosylase activity
HIN89_05210	COG4174	ABC transporter (Permease)
HIN89_05215	COG4239	(ABC) transporter, permease
HIN89_05220	COG4172	Belongs to the ABC transporter superfamily
HIN89_05240	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HIN89_05250	COG2203	Gaf domain
HIN89_05250	COG3706	GGDEF domain
HIN89_05250	COG5001	Diguanylate cyclase
HIN89_05250	COG4251	negative regulation of phosphorylation
HIN89_05260	COG1902	pentaerythritol trinitrate reductase activity
HIN89_05260	COG0446	pyridine nucleotide-disulphide oxidoreductase
HIN89_05295	COG1113	amino acid transport
HIN89_05305	COG0531	amino acid
HIN89_05325	COG1012	belongs to the aldehyde dehydrogenase family
HIN89_05345	COG1113	amino acid transport
HIN89_05360	COG0697	spore germination
HIN89_05365	COG2721	sulfolactate sulfo-lyase activity
HIN89_05370	COG2271	Major facilitator Superfamily
HIN89_05375	COG4948	Mandelate Racemase Muconate Lactonizing
HIN89_05385	COG1012	belongs to the aldehyde dehydrogenase family
HIN89_05390	COG2186	Transcriptional regulator
HIN89_05415	COG1960	acyl-CoA dehydrogenase activity
HIN89_05425	COG1012	belongs to the aldehyde dehydrogenase family
HIN89_05430	COG1024	Enoyl-CoA hydratase
HIN89_05435	COG2814	Major facilitator Superfamily
HIN89_05450	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HIN89_05465	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HIN89_05480	COG1309	transcriptional regulator
HIN89_05485	COG1741	Belongs to the pirin family
HIN89_05500	COG2072	flavoprotein involved in K transport
HIN89_05510	COG2252	PERMEase
HIN89_05515	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HIN89_05525	COG3038	cytochrome b561
HIN89_05535	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HIN89_05545	COG0527	aspartate kinase activity
HIN89_05610	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HIN89_05640	COG2194	sulfuric ester hydrolase activity
HIN89_05645	COG0582	viral genome integration into host DNA
HIN89_05655	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HIN89_05665	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HIN89_05680	COG0667	Aldo Keto reductase
HIN89_05690	COG1765	OsmC-like protein
HIN89_05705	COG0542	response to heat
HIN89_05740	COG2885	chlorophyll binding
HIN89_05750	COG0625	glutathione transferase activity
HIN89_05755	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HIN89_05775	COG3634	alkyl hydroperoxide reductase activity
HIN89_05785	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HIN89_05795	COG0450	alkyl hydroperoxide reductase
HIN89_05800	COG1643	Atp-dependent helicase
HIN89_05815	COG2814	Major facilitator Superfamily
HIN89_05820	COG3135	benzoate transporter
HIN89_05825	COG1028	Short-chain dehydrogenase reductase Sdr
HIN89_05830	COG0543	2 iron, 2 sulfur cluster binding
HIN89_05830	COG0633	Ferredoxin
HIN89_05835	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HIN89_05840	COG4638	Rieske (2fe-2S)
HIN89_05845	COG0583	DNA-binding transcription factor activity
HIN89_05855	COG2871	sodium ion transport
HIN89_05935	COG1570	exodeoxyribonuclease VII activity
HIN89_05970	COG1280	lysine exporter protein (LysE YggA)
HIN89_05975	COG1278	Cold shock
HIN89_06040	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HIN89_06040	COG0517	IMP dehydrogenase activity
HIN89_06045	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HIN89_06055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HIN89_06060	COG1137	ATPase activity
HIN89_06070	COG1538	Outer membrane efflux protein
HIN89_06100	COG4122	O-methyltransferase activity
HIN89_06110	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HIN89_06145	COG0598	Magnesium transport protein CorA
HIN89_06170	COG1250	3-hydroxyacyl-CoA dehydrogenase
HIN89_06240	COG0583	DNA-binding transcription factor activity
HIN89_06245	COG1914	H( )-stimulated, divalent metal cation uptake system
HIN89_06265	COG4770	biotin carboxylase activity
HIN89_06270	COG0038	chloride channel
HIN89_06315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HIN89_06335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HIN89_06360	COG1012	belongs to the aldehyde dehydrogenase family
HIN89_06365	COG0531	amino acid
HIN89_06370	COG1760	l-serine dehydratase
HIN89_06375	COG1012	belongs to the aldehyde dehydrogenase family
HIN89_06375	COG2030	dehydratase
HIN89_06380	COG3396	Phenylacetate-CoA oxygenase
HIN89_06385	COG3460	Phenylacetate-CoA oxygenase
HIN89_06390	COG3396	Phenylacetate-CoA oxygenase
HIN89_06395	COG2151	metal-sulfur cluster biosynthetic enzyme
HIN89_06400	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HIN89_06405	COG1024	Enoyl-CoA hydratase
HIN89_06410	COG1024	Enoyl-CoA hydratase
HIN89_06415	COG1250	3-hydroxyacyl-CoA dehydrogenase
HIN89_06420	COG0183	Belongs to the thiolase family
HIN89_06425	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HIN89_06430	COG3327	negative regulation of DNA-templated transcription, initiation
HIN89_06445	COG0753	catalase activity
HIN89_06450	COG3038	cytochrome b561
HIN89_06455	COG0154	amidase activity
HIN89_06465	COG4638	Rieske (2fe-2S)
HIN89_06480	COG2814	Major facilitator Superfamily
HIN89_06500	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HIN89_06505	COG2814	Major facilitator Superfamily
HIN89_06530	COG0583	DNA-binding transcription factor activity
HIN89_06540	COG1414	Transcriptional regulator
HIN89_06545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HIN89_06555	COG1840	ABC-type Fe3 transport system, periplasmic component
HIN89_06560	COG3842	ATPase activity
HIN89_06575	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HIN89_06580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HIN89_06600	COG0583	DNA-binding transcription factor activity
HIN89_06610	COG4770	biotin carboxylase activity
HIN89_06615	COG1024	Enoyl-CoA hydratase
HIN89_06620	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HIN89_06625	COG1960	acyl-CoA dehydrogenase activity
HIN89_06630	COG1309	transcriptional regulator
HIN89_06635	COG0318	PFAM AMP-dependent synthetase and ligase
HIN89_06655	COG0583	DNA-binding transcription factor activity
HIN89_06710	COG1028	Short-chain dehydrogenase reductase Sdr
HIN89_06735	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HIN89_06755	COG0784	Response regulator, receiver
HIN89_06755	COG2205	protein histidine kinase activity
HIN89_06795	COG0765	amino acid transport
HIN89_06800	COG0765	amino acid transport
HIN89_06805	COG1126	abc transporter atp-binding protein
HIN89_06810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HIN89_06815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HIN89_06835	COG1280	lysine exporter protein (LysE YggA)
HIN89_06840	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HIN89_06850	COG1045	serine acetyltransferase
HIN89_06860	COG1028	Short-chain dehydrogenase reductase Sdr
HIN89_06865	COG0583	DNA-binding transcription factor activity
HIN89_06870	COG0625	glutathione transferase activity
HIN89_06875	COG0625	glutathione transferase activity
HIN89_06880	COG0583	DNA-binding transcription factor activity
HIN89_06890	COG1346	cytolysis
HIN89_06910	COG2814	Major facilitator Superfamily
HIN89_06930	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
HIN89_06935	COG3052	prosthetic group binding
HIN89_06955	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HIN89_06975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HIN89_06985	COG1294	oxidase, subunit
HIN89_06990	COG1271	oxidase subunit
HIN89_07010	COG4372	Transposase
HIN89_07020	COG2963	transposase activity
HIN89_07030	COG0477	Major facilitator Superfamily
HIN89_07040	COG4521	taurine ABC transporter
HIN89_07045	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HIN89_07050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HIN89_07055	COG2175	clavaminate synthase activity
HIN89_07065	COG1953	Uracil, thiamine, allantoin
HIN89_07085	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HIN89_07100	COG0640	Transcriptional regulator
HIN89_07105	COG0798	PFAM Bile acid sodium symporter
HIN89_07110	COG0583	DNA-binding transcription factor activity
HIN89_07125	COG3634	alkyl hydroperoxide reductase activity
HIN89_07165	COG0436	Aminotransferase
HIN89_07175	COG0386	Belongs to the glutathione peroxidase family
HIN89_07215	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HIN89_07240	COG0012	GTP binding
HIN89_07245	COG2011	ABC-type metal ion transport system permease component
HIN89_07250	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HIN89_07260	COG1464	Belongs to the NlpA lipoprotein family
HIN89_07290	COG0765	amino acid transport
HIN89_07295	COG0765	amino acid transport
HIN89_07300	COG1126	abc transporter atp-binding protein
HIN89_07310	COG1522	sequence-specific DNA binding
HIN89_07325	COG1309	transcriptional regulator
HIN89_07360	COG0697	spore germination
HIN89_07385	COG3121	Chaperone
HIN89_07390	COG3539	Fimbrial protein
HIN89_07415	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HIN89_07415	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HIN89_07460	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HIN89_07470	COG2353	YceI-like domain
HIN89_07480	COG3698	Phosphodiester glycosidase
HIN89_07495	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HIN89_07500	COG0506	proline dehydrogenase activity
HIN89_07500	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HIN89_07500	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HIN89_07510	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HIN89_07515	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HIN89_07535	COG1132	(ABC) transporter
HIN89_07540	COG3122	Protein conserved in bacteria
HIN89_07545	COG3619	membrane
HIN89_07555	COG0640	Transcriptional regulator
HIN89_07565	COG2850	peptidyl-arginine hydroxylation
HIN89_07570	COG0424	maF-like protein
HIN89_07590	COG0191	fructose-bisphosphate aldolase activity
HIN89_07595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HIN89_07610	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HIN89_07620	COG1192	Involved in chromosome partitioning
HIN89_07625	COG1475	DNA binding
HIN89_07630	COG0811	peptide transport
HIN89_07640	COG1132	(ABC) transporter
HIN89_07645	COG1663	tetraacyldisaccharide 4'-kinase activity
HIN89_07665	COG0084	hydrolase, TatD family'
HIN89_07680	COG2165	general secretion pathway protein
HIN89_07730	COG0776	regulation of translation
HIN89_07750	COG3328	transposase activity
HIN89_07765	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HIN89_07770	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HIN89_07815	COG0339	signal peptide processing
HIN89_07825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIN89_07860	COG0702	epimerase
HIN89_07865	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HIN89_07875	COG2963	transposase activity
HIN89_07885	COG4372	Transposase
HIN89_07905	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HIN89_07935	COG0316	Belongs to the HesB IscA family
HIN89_07940	COG0822	iron-sulfur transferase activity
HIN89_07965	COG0776	regulation of translation
HIN89_07970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HIN89_07980	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HIN89_07985	COG1960	acyl-CoA dehydrogenase activity
HIN89_07990	COG1960	acyl-CoA dehydrogenase activity
HIN89_08005	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HIN89_08040	COG4264	IucA IucC family
HIN89_08050	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HIN89_08095	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HIN89_08100	COG0406	alpha-ribazole phosphatase activity
HIN89_08115	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HIN89_08120	COG0730	response to heat
HIN89_08140	COG4773	Receptor
HIN89_08145	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HIN89_08160	COG1131	(ABC) transporter
HIN89_08165	COG0842	Transport permease protein
HIN89_08170	COG0842	Transport permease protein
HIN89_08215	COG3293	Transposase
HIN89_08230	COG2226	methyltransferase
HIN89_08255	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HIN89_08260	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HIN89_08265	COG4372	Transposase
HIN89_08275	COG2963	transposase activity
HIN89_08305	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HIN89_08315	COG0133	tryptophan synthase activity
HIN89_08330	COG3706	GGDEF domain
HIN89_08345	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HIN89_08350	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HIN89_08355	COG0022	dehydrogenase e1 component
HIN89_08360	COG0508	dehydrogenase complex catalyzes the overall conversion of
HIN89_08365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HIN89_08375	COG1063	alcohol dehydrogenase
HIN89_08380	COG3781	membrane
HIN89_08390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HIN89_08390	COG3453	Protein conserved in bacteria
HIN89_08400	COG0730	response to heat
HIN89_08415	COG2207	Transcriptional regulator
HIN89_08415	COG3708	Transcriptional regulator
HIN89_08420	COG1733	regulation of RNA biosynthetic process
HIN89_08425	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HIN89_08435	COG2188	Transcriptional regulator
HIN89_08450	COG4521	taurine ABC transporter
HIN89_08455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HIN89_08475	COG0477	Major facilitator Superfamily
HIN89_08485	COG1027	Aspartate ammonia-lyase
HIN89_08500	COG0583	DNA-binding transcription factor activity
HIN89_08505	COG0583	DNA-binding transcription factor activity
HIN89_08510	COG0183	Belongs to the thiolase family
HIN89_08515	COG2031	fatty acid transporter
HIN89_08530	COG0583	DNA-binding transcription factor activity
HIN89_08550	COG1309	transcriptional regulator
HIN89_08565	COG1028	Short-chain dehydrogenase reductase Sdr
HIN89_08570	COG2207	Transcriptional regulator
HIN89_08585	COG1028	Short-chain dehydrogenase reductase Sdr
HIN89_08595	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HIN89_08615	COG0543	2 iron, 2 sulfur cluster binding
HIN89_08615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HIN89_08620	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HIN89_08625	COG4638	Rieske (2fe-2S)
HIN89_08635	COG0725	ABC transporter, periplasmic molybdate-binding protein
HIN89_08640	COG4149	molybdate abc transporter
HIN89_08645	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HIN89_08650	COG1028	Short-chain dehydrogenase reductase Sdr
HIN89_08655	COG3433	isochorismatase activity
HIN89_08655	COG1535	isochorismatase
HIN89_08725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIN89_08760	COG0747	negative chemotaxis
HIN89_08765	COG0601	transmembrane transport
HIN89_08770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIN89_08790	COG1132	(ABC) transporter
HIN89_08795	COG1132	(ABC) transporter
HIN89_08825	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HIN89_08830	COG3657	addiction module killer protein
HIN89_08860	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HIN89_08875	COG1979	alcohol dehydrogenase
HIN89_08885	COG1902	pentaerythritol trinitrate reductase activity
HIN89_08890	COG1309	transcriptional regulator
HIN89_08915	COG0071	Belongs to the small heat shock protein (HSP20) family
HIN89_08920	COG0542	response to heat
HIN89_08990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HIN89_09005	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
HIN89_09030	COG0745	RESPONSE REGULATOR receiver
HIN89_09050	COG2207	Transcriptional regulator
HIN89_09125	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HIN89_09195	COG1120	ATPase activity
HIN89_09210	COG1064	alcohol dehydrogenase
HIN89_09220	COG2207	Transcriptional regulator
HIN89_09225	COG2084	Dehydrogenase
HIN89_09235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HIN89_09240	COG0583	DNA-binding transcription factor activity
HIN89_09250	COG0129	dihydroxy-acid dehydratase activity
HIN89_09255	COG1012	belongs to the aldehyde dehydrogenase family
HIN89_09270	COG1566	PFAM secretion protein HlyD family protein
HIN89_09280	COG2271	Major facilitator Superfamily
HIN89_09295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HIN89_09320	COG0583	DNA-binding transcription factor activity
HIN89_09335	COG2188	Transcriptional regulator
HIN89_09390	COG1473	amidohydrolase
HIN89_09400	COG0475	glutathione-regulated potassium exporter activity
HIN89_09400	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HIN89_09410	COG0583	DNA-binding transcription factor activity
HIN89_09415	COG1335	isochorismatase
HIN89_09425	COG1309	transcriptional regulator
HIN89_09450	COG0789	Transcriptional regulator
HIN89_09465	COG0446	pyridine nucleotide-disulphide oxidoreductase
HIN89_09465	COG1902	pentaerythritol trinitrate reductase activity
HIN89_09480	COG1012	belongs to the aldehyde dehydrogenase family
HIN89_09500	COG2186	Transcriptional regulator
HIN89_09510	COG0583	DNA-binding transcription factor activity
HIN89_09515	COG4948	Mandelate Racemase Muconate Lactonizing
HIN89_09520	COG4829	muconolactone delta-isomerase
HIN89_09530	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HIN89_09535	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HIN89_09540	COG0183	Belongs to the thiolase family
HIN89_09545	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HIN89_09550	COG1012	belongs to the aldehyde dehydrogenase family
HIN89_09560	COG3733	amine oxidase
HIN89_09570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HIN89_09580	COG1028	Short-chain dehydrogenase reductase Sdr
HIN89_09590	COG4638	Rieske (2fe-2S)
HIN89_09610	COG0154	amidase activity
HIN89_09620	COG2814	Major facilitator Superfamily
HIN89_09645	COG1960	acyl-CoA dehydrogenase activity
HIN89_09650	COG0583	DNA-binding transcription factor activity
HIN89_09655	COG1414	Transcriptional regulator
HIN89_09670	COG2391	methyltransferase activity
HIN89_09680	COG4993	Dehydrogenase
HIN89_09685	COG3659	wide pore channel activity
HIN89_09690	COG3420	alginic acid biosynthetic process
HIN89_09695	COG0710	3-dehydroquinate dehydratase activity
HIN89_09700	COG3485	protocatechuate 3,4-dioxygenase
HIN89_09705	COG3485	protocatechuate 3,4-dioxygenase
HIN89_09710	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HIN89_09715	COG2271	Major facilitator Superfamily
HIN89_09720	COG0596	Alpha beta hydrolase
HIN89_09725	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HIN89_09730	COG0183	Belongs to the thiolase family
HIN89_09735	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HIN89_09740	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HIN89_09750	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HIN89_09755	COG2323	membrane
HIN89_09800	COG0446	pyridine nucleotide-disulphide oxidoreductase
HIN89_09800	COG1902	pentaerythritol trinitrate reductase activity
HIN89_09825	COG0542	response to heat
HIN89_09830	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HIN89_09860	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HIN89_09865	COG0569	domain protein
HIN89_09870	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HIN89_09885	COG3328	transposase activity
HIN89_09895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HIN89_09905	COG1585	Membrane protein implicated in regulation of membrane protease activity
HIN89_09920	COG1294	oxidase, subunit
HIN89_09925	COG4890	Cyd operon protein YbgT
HIN89_09940	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HIN89_09950	COG0552	protein localization to endoplasmic reticulum
HIN89_09975	COG0516	GMP reductase activity
HIN89_09975	COG0517	IMP dehydrogenase activity
HIN89_09980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HIN89_09985	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HIN89_09995	COG0583	DNA-binding transcription factor activity
HIN89_10000	COG0024	Methionine aminopeptidase
HIN89_10030	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HIN89_10030	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HIN89_10035	COG1105	Belongs to the carbohydrate kinase PfkB family
HIN89_10040	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HIN89_10040	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HIN89_10040	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HIN89_10055	COG5001	Diguanylate cyclase
HIN89_10055	COG3300	MHYT domain
HIN89_10070	COG2135	peptidase activity
HIN89_10085	COG0659	secondary active sulfate transmembrane transporter activity
HIN89_10105	COG1113	amino acid transport
HIN89_10115	COG1522	sequence-specific DNA binding
HIN89_10140	COG1011	Hydrolase
HIN89_10145	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HIN89_10155	COG2137	regulation of response to DNA damage stimulus
HIN89_10170	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HIN89_10205	COG0575	Belongs to the CDS family
HIN89_10210	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HIN89_10235	COG3852	Histidine kinase
HIN89_10240	COG2204	response regulator
HIN89_10295	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HIN89_10300	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HIN89_10320	COG0697	spore germination
HIN89_10335	COG0303	'Molybdopterin
HIN89_10340	COG0521	Mo-molybdopterin cofactor biosynthetic process
HIN89_10340	COG0315	cyclic pyranopterin monophosphate synthase activity
HIN89_10355	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HIN89_10360	COG0243	molybdopterin cofactor binding
HIN89_10370	COG0243	molybdopterin cofactor binding
HIN89_10375	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HIN89_10380	COG2146	nitrite reductase [NAD(P)H] activity
HIN89_10380	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HIN89_10390	COG0745	RESPONSE REGULATOR receiver
HIN89_10395	COG1116	anion transmembrane transporter activity
HIN89_10395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HIN89_10415	COG0511	ligase activity, forming carbon-carbon bonds
HIN89_10430	COG2814	Major facilitator Superfamily
HIN89_10450	COG0069	glutamate synthase activity
HIN89_10470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HIN89_10480	COG1454	alcohol dehydrogenase
HIN89_10485	COG0824	Thioesterase
HIN89_10495	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HIN89_10515	COG2030	dehydratase
HIN89_10525	COG0183	Belongs to the thiolase family
HIN89_10535	COG0583	DNA-binding transcription factor activity
HIN89_10540	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HIN89_10550	COG1522	sequence-specific DNA binding
HIN89_10555	COG3135	benzoate transporter
HIN89_10590	COG0589	response to stress
HIN89_10595	COG0488	(ABC) transporter
HIN89_10620	COG4773	Receptor
HIN89_10635	COG3328	transposase activity
HIN89_10655	COG0668	transmembrane transport
HIN89_10665	COG1309	transcriptional regulator
HIN89_10670	COG2963	transposase activity
HIN89_10680	COG4372	Transposase
HIN89_10710	COG1605	Chorismate mutase
HIN89_10730	COG0308	aminopeptidase N
HIN89_10750	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HIN89_10760	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HIN89_10765	COG1454	alcohol dehydrogenase
HIN89_10785	COG0531	amino acid
HIN89_10790	COG4303	Ethanolamine ammonia lyase large subunit
HIN89_10795	COG4302	ethanolamine ammonia-lyase activity
HIN89_10800	COG0519	Catalyzes the synthesis of GMP from XMP
HIN89_10800	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HIN89_10805	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HIN89_10835	COG0697	spore germination
HIN89_10840	COG1923	regulation of RNA biosynthetic process
HIN89_10850	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HIN89_10855	COG0802	atpase or kinase
HIN89_10875	COG1187	pseudouridine synthase activity
HIN89_10895	COG0583	DNA-binding transcription factor activity
HIN89_10985	COG2814	Major facilitator Superfamily
HIN89_10990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HIN89_11015	COG0729	surface antigen
HIN89_11035	COG0174	glutamine synthetase
HIN89_11040	COG0745	RESPONSE REGULATOR receiver
HIN89_11045	COG2205	protein histidine kinase activity
HIN89_11055	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HIN89_11060	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HIN89_11070	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HIN89_11085	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HIN89_11090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HIN89_11095	COG1960	acyl-CoA dehydrogenase activity
HIN89_11110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HIN89_11115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HIN89_11130	COG3328	transposase activity
HIN89_11140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HIN89_11150	COG3658	cytochrome
HIN89_11155	COG1215	transferase activity, transferring glycosyl groups
HIN89_11160	COG0726	polysaccharide deacetylase
HIN89_11160	COG1649	PFAM Uncharacterised BCR, COG1649
HIN89_11185	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HIN89_11190	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HIN89_11200	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HIN89_11225	COG0305	Participates in initiation and elongation during chromosome replication
HIN89_11230	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HIN89_11240	COG1305	Transglutaminase-like
HIN89_11250	COG2308	Evidence 4 Homologs of previously reported genes of
HIN89_11280	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HIN89_11285	COG0138	bifunctional purine biosynthesis protein purh
HIN89_11290	COG0151	Belongs to the GarS family
HIN89_11295	COG1464	Belongs to the NlpA lipoprotein family
HIN89_11300	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HIN89_11305	COG2011	ABC-type metal ion transport system permease component
HIN89_11310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HIN89_11320	COG1301	dicarboxylic acid transport
HIN89_11350	COG1794	racemase activity, acting on amino acids and derivatives
HIN89_11360	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HIN89_11360	COG3008	intermembrane lipid transfer
HIN89_11365	COG2995	paraquat-inducible protein a
HIN89_11420	COG1051	belongs to the nudix hydrolase family
HIN89_11425	COG0477	Major facilitator Superfamily
HIN89_11480	COG2186	Transcriptional regulator
HIN89_11490	COG0786	glutamate:sodium symporter activity
HIN89_11495	COG3243	poly(R)-hydroxyalkanoic acid synthase
HIN89_11520	COG3111	PFAM Bacterial OB fold (BOF) protein
HIN89_11590	COG2815	serine threonine protein kinase
HIN89_11590	COG0515	serine threonine protein kinase
HIN89_11620	COG1610	YqeY-like protein
HIN89_11625	COG4783	chaperone-mediated protein folding
HIN89_11650	COG1286	toxin biosynthetic process
HIN89_11680	COG0778	Nitroreductase
HIN89_11690	COG0513	Belongs to the DEAD box helicase family
HIN89_11710	COG2363	Small membrane protein
HIN89_11740	COG1234	tRNA 3'-trailer cleavage
HIN89_11745	COG2195	Cleaves the N-terminal amino acid of tripeptides
HIN89_11755	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HIN89_11770	COG1960	acyl-CoA dehydrogenase activity
HIN89_11775	COG1301	dicarboxylic acid transport
HIN89_11780	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HIN89_11785	COG3139	Protein of unknown function (DUF1315)
HIN89_11790	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HIN89_11795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HIN89_11805	COG0494	nUDIX hydrolase
HIN89_11815	COG0642	Histidine kinase
HIN89_11820	COG0745	RESPONSE REGULATOR receiver
HIN89_11840	COG1720	tRNA m6t6A37 methyltransferase activity
HIN89_11855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HIN89_11865	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HIN89_11875	COG4598	ABC transporter
HIN89_11880	COG4160	amino acid transport
HIN89_11885	COG4215	(ABC) transporter
HIN89_11945	COG1131	(ABC) transporter
HIN89_11950	COG0842	Transport permease protein
HIN89_11965	COG0772	Belongs to the SEDS family
HIN89_11970	COG2951	lytic endotransglycosylase activity
HIN89_11995	COG2207	Transcriptional regulator
HIN89_12010	COG0052	Belongs to the universal ribosomal protein uS2 family
HIN89_12015	COG0024	Methionine aminopeptidase
HIN89_12025	COG2223	nitrite transmembrane transporter activity
HIN89_12035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HIN89_12040	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HIN89_12045	COG1960	acyl-CoA dehydrogenase activity
HIN89_12060	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HIN89_12065	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HIN89_12070	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HIN89_12090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HIN89_12095	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HIN89_12100	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HIN89_12135	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HIN89_12145	COG0174	glutamine synthetase
HIN89_12150	COG3104	oligopeptide transport
HIN89_12160	COG0512	Glutamine amidotransferase of anthranilate synthase
HIN89_12165	COG0308	aminopeptidase N
HIN89_12195	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HIN89_12225	COG3739	integral membrane protein
HIN89_12250	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HIN89_12255	COG5265	(ABC) transporter
HIN89_12260	COG1132	(ABC) transporter
HIN89_12275	COG1535	isochorismatase
HIN89_12275	COG3433	isochorismatase activity
HIN89_12280	COG1021	2,3-dihydroxybenzoate-AMP ligase
HIN89_12285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HIN89_12295	COG4774	siderophore transport
HIN89_12300	COG4607	ABC-type enterochelin transport system periplasmic component
HIN89_12305	COG4604	ABC transporter, ATP-binding protein
HIN89_12310	COG4605	iron ion homeostasis
HIN89_12315	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIN89_12320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HIN89_12335	COG2964	Protein conserved in bacteria
HIN89_12345	COG1741	Belongs to the pirin family
HIN89_12375	COG2828	Protein conserved in bacteria
HIN89_12380	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HIN89_12385	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HIN89_12390	COG0583	DNA-binding transcription factor activity
HIN89_12425	COG1309	transcriptional regulator
HIN89_12430	COG1012	belongs to the aldehyde dehydrogenase family
HIN89_12435	COG0477	Major facilitator Superfamily
HIN89_12450	COG1522	sequence-specific DNA binding
HIN89_12455	COG4638	Rieske (2fe-2S)
HIN89_12470	COG3961	Belongs to the TPP enzyme family
HIN89_12485	COG2879	small protein
HIN89_12490	COG1966	Carbon starvation protein
HIN89_12510	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HIN89_12535	COG1067	ATP-dependent peptidase activity
HIN89_12540	COG0583	DNA-binding transcription factor activity
HIN89_12565	COG1686	Belongs to the peptidase S11 family
HIN89_12570	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HIN89_12605	COG0616	signal peptide processing
HIN89_12610	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HIN89_12620	COG0573	inorganic phosphate transmembrane transporter activity
HIN89_12625	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HIN89_12630	COG1113	amino acid transport
HIN89_12635	COG3961	Belongs to the TPP enzyme family
HIN89_12640	COG1522	sequence-specific DNA binding
HIN89_12650	COG3328	transposase activity
HIN89_12660	COG0076	glutamate decarboxylase activity
HIN89_12665	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HIN89_12675	COG1309	transcriptional regulator
HIN89_12690	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HIN89_12725	COG0352	thiamine-phosphate diphosphorylase activity
HIN89_12750	COG1203	CRISPR-associated helicase, Cas3
HIN89_12785	COG0612	Peptidase, M16
HIN89_12800	COG0583	DNA-binding transcription factor activity
HIN89_12805	COG0477	Major facilitator Superfamily
HIN89_12830	COG1187	pseudouridine synthase activity
HIN89_12845	COG1686	Belongs to the peptidase S11 family
HIN89_12850	COG1252	NADH dehydrogenase
HIN89_12860	COG0415	Belongs to the DNA photolyase family
HIN89_12880	COG2070	2-Nitropropane dioxygenase
HIN89_12935	COG0556	nucleotide-excision repair
HIN89_12955	COG0436	Aminotransferase
HIN89_12970	COG0443	Heat shock 70 kDa protein
HIN89_13000	COG4221	oxidoreductase activity
HIN89_13010	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HIN89_13015	COG1381	Involved in DNA repair and RecF pathway recombination
HIN89_13025	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HIN89_13040	COG0681	Belongs to the peptidase S26 family
HIN89_13055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HIN89_13075	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HIN89_13080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HIN89_13085	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HIN89_13095	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HIN89_13100	COG4208	sulfate ABC transporter
HIN89_13105	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HIN89_13110	COG0583	DNA-binding transcription factor activity
HIN89_13115	COG4625	pathogenesis
HIN89_13130	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HIN89_13145	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HIN89_13155	COG1051	belongs to the nudix hydrolase family
HIN89_13155	COG1056	cytidyltransferase-related domain
HIN89_13160	COG1024	Enoyl-CoA hydratase
HIN89_13170	COG2814	Major facilitator Superfamily
HIN89_13175	COG0047	phosphoribosylformylglycinamidine synthase activity
HIN89_13175	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HIN89_13195	COG1473	amidohydrolase
HIN89_13200	COG0824	Thioesterase
HIN89_13220	COG0823	Involved in the tonB-independent uptake of proteins
HIN89_13240	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HIN89_13285	COG0628	permease
HIN89_13295	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HIN89_13300	COG0596	Alpha beta hydrolase
HIN89_13305	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HIN89_13305	COG0616	signal peptide processing
HIN89_13315	COG2333	competence protein COMEC
HIN89_13315	COG0658	competence protein
HIN89_13320	COG1136	(ABC) transporter
HIN89_13325	COG4591	ABC-type transport system involved in lipoprotein release permease component
HIN89_13360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HIN89_13380	COG0463	Glycosyl transferase, family 2
HIN89_13410	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HIN89_13415	COG1280	lysine exporter protein (LysE YggA)
HIN89_13425	COG0019	diaminopimelate decarboxylase activity
HIN89_13435	COG1113	amino acid transport
HIN89_13450	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
HIN89_13460	COG3339	Conserved Protein
HIN89_13465	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HIN89_13470	COG0243	molybdopterin cofactor binding
HIN89_13475	COG1929	Belongs to the glycerate kinase type-1 family
HIN89_13490	COG0778	Nitroreductase
HIN89_13520	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HIN89_13525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HIN89_13540	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HIN89_13560	COG0741	lytic transglycosylase activity
HIN89_13580	COG0584	glycerophosphoryl diester phosphodiesterase
HIN89_13585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HIN89_13605	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HIN89_13610	COG1597	lipid kinase activity
HIN89_13625	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HIN89_13630	COG0477	Major facilitator Superfamily
HIN89_13680	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HIN89_13685	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HIN89_13710	COG0505	Belongs to the CarA family
HIN89_13725	COG1309	transcriptional regulator
HIN89_13730	COG0251	oxidation-reduction process
HIN89_13740	COG0589	response to stress
HIN89_13755	COG2843	Capsule synthesis protein
HIN89_13775	COG2321	neutral zinc metallopeptidase
HIN89_13780	COG2354	Protein conserved in bacteria
HIN89_13800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HIN89_13825	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HIN89_13830	COG1053	succinate dehydrogenase
HIN89_13835	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HIN89_13840	COG2009	succinate dehydrogenase
HIN89_13875	COG2921	Belongs to the UPF0250 family
HIN89_13880	COG0321	lipoyl(octanoyl) transferase activity
HIN89_13895	COG0531	amino acid
HIN89_13905	COG1733	regulation of RNA biosynthetic process
HIN89_13910	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HIN89_13915	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HIN89_13915	COG1648	precorrin-2 dehydrogenase activity
HIN89_13935	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HIN89_13965	COG0671	phosphoesterase, PA-phosphatase related
HIN89_13970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HIN89_13980	COG1538	Outer membrane efflux protein
HIN89_13985	COG0393	Putative heavy-metal-binding
HIN89_13990	COG0393	Putative heavy-metal-binding
HIN89_14000	COG1028	Short-chain dehydrogenase reductase Sdr
HIN89_14010	COG0525	valine-tRNA ligase activity
HIN89_14035	COG0583	DNA-binding transcription factor activity
HIN89_14040	COG0004	ammonium transporteR
HIN89_14050	COG0642	Histidine kinase
HIN89_14055	COG0745	RESPONSE REGULATOR receiver
HIN89_14060	COG2194	sulfuric ester hydrolase activity
HIN89_14080	COG1752	Esterase of the alpha-beta hydrolase superfamily
HIN89_14095	COG2315	Protein conserved in bacteria
HIN89_14100	COG0142	geranyltranstransferase activity
HIN89_14105	COG2828	Protein conserved in bacteria
HIN89_14110	COG1113	amino acid transport
HIN89_14125	COG3328	transposase activity
HIN89_14155	COG2963	transposase activity
HIN89_14165	COG4372	Transposase
HIN89_14185	COG3328	transposase activity
HIN89_14210	COG3328	transposase activity
HIN89_14235	COG2207	Transcriptional regulator
HIN89_14260	COG2249	NAD(P)H dehydrogenase (quinone) activity
HIN89_14270	COG0560	Phosphoserine phosphatase
HIN89_14280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HIN89_14290	COG1530	ribonuclease E activity
HIN89_14295	COG0424	maF-like protein
HIN89_14300	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HIN89_14305	COG1792	Involved in formation and maintenance of cell shape
HIN89_14310	COG1077	Cell shape determining protein MreB Mrl
HIN89_14315	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HIN89_14325	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HIN89_14350	COG3590	peptidase
HIN89_14355	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HIN89_14360	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HIN89_14365	COG1752	Esterase of the alpha-beta hydrolase superfamily
HIN89_14370	COG1115	amino acid carrier protein
HIN89_14390	COG2814	Major facilitator Superfamily
HIN89_14395	COG1289	transmembrane transporter activity
HIN89_14405	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HIN89_14445	COG1376	ErfK ybiS ycfS ynhG family protein
HIN89_14450	COG2832	Protein of unknown function (DUF454)
HIN89_14460	COG5510	response to toxic substance
HIN89_14480	COG0840	transmembrane signaling receptor activity
HIN89_14520	COG3422	double-strand break repair
HIN89_14525	COG2824	Alkylphosphonate utilization operon protein PhnA
HIN89_14540	COG0354	folic acid binding
HIN89_14545	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HIN89_14555	COG0679	Auxin Efflux Carrier
HIN89_14560	COG1902	pentaerythritol trinitrate reductase activity
HIN89_14565	COG4772	TonB-dependent receptor
HIN89_14570	COG2094	Belongs to the DNA glycosylase MPG family
HIN89_14600	COG2233	PERMEase
HIN89_14610	COG0833	amino acid
HIN89_14615	COG1690	Belongs to the RtcB family
HIN89_14625	COG2885	chlorophyll binding
HIN89_14625	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HIN89_14635	COG0183	Belongs to the thiolase family
HIN89_14655	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HIN89_14675	COG2207	Transcriptional regulator
HIN89_14680	COG0183	Belongs to the thiolase family
HIN89_14700	COG2153	protein acetylation
HIN89_14710	COG1272	protein, Hemolysin III
HIN89_14715	COG0477	Major facilitator Superfamily
HIN89_14730	COG0450	alkyl hydroperoxide reductase
HIN89_14750	COG0285	dihydrofolate synthase activity
HIN89_14800	COG2096	Adenosyltransferase
HIN89_14820	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HIN89_14825	COG0745	RESPONSE REGULATOR receiver
HIN89_14830	COG2205	protein histidine kinase activity
HIN89_14845	COG1960	acyl-CoA dehydrogenase activity
HIN89_14850	COG1960	acyl-CoA dehydrogenase activity
HIN89_14900	COG1442	glycosyl transferase family 8
HIN89_14915	COG0438	transferase activity, transferring glycosyl groups
HIN89_14925	COG0438	transferase activity, transferring glycosyl groups
HIN89_14930	COG0726	polysaccharide deacetylase
HIN89_14945	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HIN89_14950	COG2205	protein histidine kinase activity
HIN89_14985	COG1862	Preprotein translocase
HIN89_14995	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HIN89_15005	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HIN89_15015	COG3781	membrane
HIN89_15020	COG0613	PHP domain protein
HIN89_15030	COG2350	Protein conserved in bacteria
HIN89_15060	COG1607	acyl-coa hydrolase
HIN89_15120	COG2199	diguanylate cyclase activity
HIN89_15130	COG1408	metallophosphoesterase
HIN89_15135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIN89_15145	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HIN89_15165	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HIN89_15170	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HIN89_15185	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HIN89_15195	COG2969	positive regulation of protein catabolic process
HIN89_15215	COG1960	acyl-CoA dehydrogenase activity
HIN89_15220	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HIN89_15235	COG1309	transcriptional regulator
HIN89_15240	COG1960	acyl-CoA dehydrogenase activity
HIN89_15285	COG1183	phosphatidylcholine synthase activity
HIN89_15290	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HIN89_15320	COG0739	heme binding
HIN89_15320	COG0741	lytic transglycosylase activity
HIN89_15320	COG1196	nuclear chromosome segregation
HIN89_15330	COG1702	phosphate starvation-inducible protein PhoH
HIN89_15365	COG1295	ribonuclease BN
HIN89_15370	COG0697	spore germination
HIN89_15375	COG2169	Transcriptional regulator
HIN89_15380	COG0179	Fumarylacetoacetate (FAA) hydrolase
HIN89_15425	COG0557	exoribonuclease II activity
HIN89_15430	COG0339	signal peptide processing
HIN89_15435	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HIN89_15465	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HIN89_15470	COG1960	acyl-CoA dehydrogenase activity
HIN89_15630	COG0626	cystathionine gamma-synthase activity
HIN89_15635	COG0433	COG0433 Predicted ATPase
HIN89_15645	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HIN89_15645	COG1017	nitric oxide dioxygenase activity
HIN89_15650	COG1959	2 iron, 2 sulfur cluster binding
HIN89_15665	COG1301	dicarboxylic acid transport
HIN89_15670	COG1946	Acyl-CoA thioesterase
HIN89_15690	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HIN89_15695	COG1040	competence protein
HIN89_15700	COG0494	nUDIX hydrolase
HIN89_15710	COG0598	Magnesium transport protein CorA
HIN89_15720	COG2854	intermembrane phospholipid transfer
HIN89_15730	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HIN89_15735	COG1127	ABC transporter
HIN89_15745	COG0513	Belongs to the DEAD box helicase family
HIN89_15765	COG0408	coproporphyrinogen oxidase activity
HIN89_15780	COG1960	acyl-CoA dehydrogenase activity
HIN89_15790	COG1983	PspC domain protein
HIN89_15795	COG0517	IMP dehydrogenase activity
HIN89_15830	COG1106	Psort location Cytoplasmic, score
HIN89_15850	COG0583	DNA-binding transcription factor activity
HIN89_15890	COG1012	belongs to the aldehyde dehydrogenase family
HIN89_15900	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HIN89_15905	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HIN89_15910	COG0833	amino acid
HIN89_15940	COG1192	Involved in chromosome partitioning
HIN89_15945	COG0628	permease
HIN89_15955	COG1289	transmembrane transporter activity
HIN89_15970	COG2249	NAD(P)H dehydrogenase (quinone) activity
HIN89_15975	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HIN89_15985	COG0277	FAD linked oxidase domain protein
HIN89_15990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HIN89_16015	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HIN89_16020	COG5380	lipid catabolic process
HIN89_16040	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HIN89_16090	COG0194	GDP metabolic process
HIN89_16105	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HIN89_16125	COG3307	-O-antigen
HIN89_16140	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HIN89_16145	COG1704	LemA family
HIN89_16155	COG0493	'glutamate synthase
HIN89_16160	COG0070	glutamate synthase
HIN89_16160	COG0069	glutamate synthase activity
HIN89_16160	COG0067	glutamate synthase
HIN89_16210	COG2226	methyltransferase
HIN89_16225	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HIN89_16230	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HIN89_16275	COG0833	amino acid
HIN89_16340	COG0488	(ABC) transporter
HIN89_16345	COG2873	o-acetylhomoserine
HIN89_16350	COG4221	oxidoreductase activity
HIN89_16355	COG0659	secondary active sulfate transmembrane transporter activity
HIN89_16365	COG0745	RESPONSE REGULATOR receiver
HIN89_16380	COG0427	acetyl-CoA hydrolase
HIN89_16410	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HIN89_16445	COG2329	Antibiotic biosynthesis monooxygenase
HIN89_16460	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HIN89_16515	COG0582	viral genome integration into host DNA
HIN89_16535	COG3293	Transposase
HIN89_16560	COG2814	Major facilitator Superfamily
HIN89_16625	COG2814	Major facilitator Superfamily
HIN89_16655	COG1335	isochorismatase
HIN89_16665	COG1012	belongs to the aldehyde dehydrogenase family
HIN89_16670	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HIN89_16680	COG1113	amino acid transport
HIN89_16690	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HIN89_16705	COG2814	Major facilitator Superfamily
HIN89_16715	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HIN89_16715	COG0352	thiamine-phosphate diphosphorylase activity
HIN89_16715	COG0351	phosphomethylpyrimidine kinase
HIN89_16735	COG1309	transcriptional regulator
HIN89_16740	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HIN89_16745	COG3706	GGDEF domain
HIN89_16755	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HIN89_16765	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HIN89_16770	COG3162	membrane
HIN89_16775	COG2205	protein histidine kinase activity
HIN89_16775	COG2198	Histidine kinase
HIN89_16775	COG0784	Response regulator, receiver
HIN89_16800	COG1522	sequence-specific DNA binding
HIN89_16805	COG1335	isochorismatase
HIN89_16810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HIN89_16820	COG0668	transmembrane transport
HIN89_16825	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HIN89_16830	COG1519	Transferase
HIN89_16835	COG1902	pentaerythritol trinitrate reductase activity
HIN89_16855	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HIN89_16880	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HIN89_16880	COG0426	domain, Protein
HIN89_16890	COG3328	transposase activity
HIN89_16900	COG2119	membrane
HIN89_16910	COG0508	dehydrogenase complex catalyzes the overall conversion of
HIN89_16920	COG4942	peptidase
HIN89_16935	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HIN89_16945	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HIN89_16965	COG0189	ligase activity
HIN89_16995	COG0708	Exodeoxyribonuclease III
HIN89_17000	COG1393	Belongs to the ArsC family
HIN89_17015	COG3706	GGDEF domain
HIN89_17050	COG2351	hydroxyisourate hydrolase activity
HIN89_17055	COG2233	PERMEase
HIN89_17065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HIN89_17075	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
HIN89_17080	COG1028	Short-chain dehydrogenase reductase Sdr
HIN89_17090	COG3150	esterase
HIN89_17150	COG2918	glutathione biosynthetic process
HIN89_17165	COG2733	membrane
HIN89_17170	COG0436	Aminotransferase
HIN89_17175	COG0534	Mate efflux family protein
HIN89_17260	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HIN89_17265	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HIN89_17275	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HIN89_17330	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HIN89_17395	COG0010	Belongs to the arginase family
HIN89_17425	COG2188	Transcriptional regulator
HIN89_17435	COG0523	cobalamin synthesis protein
HIN89_17445	COG1113	amino acid transport
HIN89_17455	COG0625	glutathione transferase activity
HIN89_17470	COG3328	transposase activity
HIN89_17480	COG1683	Conserved Protein
HIN89_17485	COG0534	Mate efflux family protein
HIN89_17490	COG0385	Bile acid
HIN89_17495	COG1335	isochorismatase
HIN89_17500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HIN89_17520	COG2116	formate transmembrane transporter activity
HIN89_17525	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HIN89_17530	COG2133	pyrroloquinoline quinone binding
HIN89_17535	COG2983	Belongs to the UPF0260 family
HIN89_17555	COG1194	a g-specific adenine glycosylase
HIN89_17570	COG2818	Glycosylase
HIN89_17575	COG1064	alcohol dehydrogenase
HIN89_17580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HIN89_17595	COG0583	DNA-binding transcription factor activity
HIN89_17605	COG2814	Major facilitator Superfamily
HIN89_17640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HIN89_17655	COG2233	PERMEase
HIN89_17660	COG0583	DNA-binding transcription factor activity
HIN89_17685	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HIN89_17695	COG0733	neurotransmitter:sodium symporter activity
HIN89_17735	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HIN89_17790	COG2951	lytic endotransglycosylase activity
HIN89_17795	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HIN89_17810	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HIN89_17820	COG0671	phosphoesterase, PA-phosphatase related
HIN89_17825	COG0861	Integral membrane protein TerC family
HIN89_17835	COG0754	glutathionylspermidine amidase activity
HIN89_17845	COG0402	S-adenosylhomocysteine deaminase activity
HIN89_17860	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HIN89_17865	COG1230	cation diffusion facilitator family transporter
HIN89_17880	COG0706	membrane insertase activity
HIN89_17925	COG0210	DNA helicase
HIN89_17945	COG0210	DNA helicase
HIN89_17985	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HIN89_17990	COG2801	Transposase and inactivated derivatives
HIN89_18000	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
HIN89_18025	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HIN89_18045	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HIN89_18125	COG2801	Transposase and inactivated derivatives
HIN89_18140	COG2801	Transposase and inactivated derivatives
HIN89_18170	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HIN89_18175	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HIN89_18180	COG0732	type I restriction modification DNA specificity domain
HIN89_18190	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HIN89_18210	COG1192	Involved in chromosome partitioning
HIN89_18260	COG1373	ATPase (AAA superfamily
HIN89_18290	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HIN89_18295	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HIN89_18315	COG2369	cell adhesion
HIN89_18320	COG0582	viral genome integration into host DNA
HIN89_18340	COG2801	Transposase and inactivated derivatives
HIN89_18410	COG2963	transposase activity
HIN89_18435	COG2233	PERMEase
HIN89_18455	COG0583	DNA-binding transcription factor activity
HIN89_18480	COG0589	response to stress
HIN89_18485	COG0659	secondary active sulfate transmembrane transporter activity
HIN89_18490	COG2801	Transposase and inactivated derivatives
HIN89_18505	COG2801	Transposase and inactivated derivatives
HIN89_18555	COG2963	transposase activity
HIN89_18600	COG0583	DNA-binding transcription factor activity
HIN89_18630	COG0659	secondary active sulfate transmembrane transporter activity
HIN89_18660	COG2801	Transposase and inactivated derivatives
HIN89_18675	COG3077	Addiction module antitoxin, RelB DinJ family
HIN89_18700	COG2801	Transposase and inactivated derivatives
HIN89_18735	COG2801	Transposase and inactivated derivatives
HIN89_18750	COG3077	Addiction module antitoxin, RelB DinJ family
HIN89_18775	COG2801	Transposase and inactivated derivatives