locus-tag	class	description
ACX61_00010	COG0592	DNA-directed DNA polymerase activity
ACX61_00020	COG0187	DNA topoisomerase II activity
ACX61_00030	COG0586	Pfam SNARE associated Golgi protein
ACX61_00035	COG0488	(ABC) transporter
ACX61_00060	COG0596	Alpha beta hydrolase
ACX61_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ACX61_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ACX61_00110	COG0733	neurotransmitter:sodium symporter activity
ACX61_00145	COG0583	DNA-binding transcription factor activity
ACX61_00150	COG2233	PERMEase
ACX61_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACX61_00200	COG2814	Major facilitator Superfamily
ACX61_00205	COG0656	L-ascorbic acid biosynthetic process
ACX61_00210	COG0583	DNA-binding transcription factor activity
ACX61_00220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACX61_00225	COG1064	alcohol dehydrogenase
ACX61_00230	COG2818	Glycosylase
ACX61_00245	COG1194	a g-specific adenine glycosylase
ACX61_00265	COG2983	Belongs to the UPF0260 family
ACX61_00270	COG2133	pyrroloquinoline quinone binding
ACX61_00275	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ACX61_00280	COG2116	formate transmembrane transporter activity
ACX61_00300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACX61_00305	COG1335	isochorismatase
ACX61_00310	COG0385	Bile acid
ACX61_00315	COG0534	Mate efflux family protein
ACX61_00320	COG1683	Conserved Protein
ACX61_00340	COG0625	glutathione transferase activity
ACX61_00350	COG1113	amino acid transport
ACX61_00360	COG0523	cobalamin synthesis protein
ACX61_00370	COG2188	Transcriptional regulator
ACX61_00400	COG0010	Belongs to the arginase family
ACX61_00415	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ACX61_00420	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACX61_00430	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ACX61_00435	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ACX61_00525	COG0436	Aminotransferase
ACX61_00530	COG2733	membrane
ACX61_00545	COG2918	glutathione biosynthetic process
ACX61_00600	COG3316	Transposase and inactivated derivatives
ACX61_00610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACX61_00630	COG3501	Rhs element vgr protein
ACX61_00695	COG3150	esterase
ACX61_00705	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_00710	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
ACX61_00720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACX61_00735	COG2233	PERMEase
ACX61_00740	COG2351	hydroxyisourate hydrolase activity
ACX61_00775	COG3706	GGDEF domain
ACX61_00790	COG1393	Belongs to the ArsC family
ACX61_00795	COG0708	Exodeoxyribonuclease III
ACX61_00820	COG0189	ligase activity
ACX61_00840	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ACX61_00850	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ACX61_00865	COG4942	peptidase
ACX61_00875	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACX61_00885	COG2119	membrane
ACX61_00890	COG4774	siderophore transport
ACX61_00895	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACX61_00895	COG0426	domain, Protein
ACX61_00920	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ACX61_00940	COG1902	pentaerythritol trinitrate reductase activity
ACX61_00945	COG1519	Transferase
ACX61_00950	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ACX61_00955	COG0668	transmembrane transport
ACX61_00965	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACX61_00970	COG1335	isochorismatase
ACX61_00975	COG1522	sequence-specific DNA binding
ACX61_01000	COG2198	Histidine kinase
ACX61_01000	COG0784	Response regulator, receiver
ACX61_01000	COG2205	protein histidine kinase activity
ACX61_01005	COG3162	membrane
ACX61_01010	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACX61_01020	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACX61_01030	COG3706	GGDEF domain
ACX61_01035	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ACX61_01040	COG1309	transcriptional regulator
ACX61_01060	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ACX61_01060	COG0351	phosphomethylpyrimidine kinase
ACX61_01060	COG0352	thiamine-phosphate diphosphorylase activity
ACX61_01070	COG2814	Major facilitator Superfamily
ACX61_01085	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ACX61_01095	COG1113	amino acid transport
ACX61_01105	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ACX61_01110	COG1012	belongs to the aldehyde dehydrogenase family
ACX61_01120	COG1335	isochorismatase
ACX61_01150	COG2814	Major facilitator Superfamily
ACX61_01155	COG0583	DNA-binding transcription factor activity
ACX61_01215	COG0667	Aldo Keto reductase
ACX61_01235	COG1129	ABC transporter
ACX61_01240	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ACX61_01245	COG2207	Transcriptional regulator
ACX61_01300	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ACX61_01315	COG2329	Antibiotic biosynthesis monooxygenase
ACX61_01330	COG1132	(ABC) transporter
ACX61_01350	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ACX61_01380	COG0427	acetyl-CoA hydrolase
ACX61_01390	COG0745	RESPONSE REGULATOR receiver
ACX61_01400	COG0659	secondary active sulfate transmembrane transporter activity
ACX61_01405	COG4221	oxidoreductase activity
ACX61_01415	COG0488	(ABC) transporter
ACX61_01480	COG0833	amino acid
ACX61_01525	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ACX61_01530	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ACX61_01545	COG2226	methyltransferase
ACX61_01595	COG0070	glutamate synthase
ACX61_01595	COG0069	glutamate synthase activity
ACX61_01595	COG0067	glutamate synthase
ACX61_01600	COG0493	'glutamate synthase
ACX61_01610	COG1704	LemA family
ACX61_01615	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ACX61_01635	COG3307	-O-antigen
ACX61_01655	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACX61_01665	COG0194	GDP metabolic process
ACX61_01715	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ACX61_01735	COG5380	lipid catabolic process
ACX61_01740	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ACX61_01765	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACX61_01770	COG0277	FAD linked oxidase domain protein
ACX61_01780	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ACX61_01785	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACX61_01800	COG1289	transmembrane transporter activity
ACX61_01810	COG0628	permease
ACX61_01815	COG1192	Involved in chromosome partitioning
ACX61_01845	COG0833	amino acid
ACX61_01850	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ACX61_01855	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACX61_01865	COG1012	belongs to the aldehyde dehydrogenase family
ACX61_01905	COG0583	DNA-binding transcription factor activity
ACX61_01965	COG0517	IMP dehydrogenase activity
ACX61_01970	COG1983	PspC domain protein
ACX61_01980	COG1960	acyl-CoA dehydrogenase activity
ACX61_01995	COG0408	coproporphyrinogen oxidase activity
ACX61_02015	COG0513	Belongs to the DEAD box helicase family
ACX61_02025	COG1127	ABC transporter
ACX61_02030	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACX61_02040	COG2854	intermembrane phospholipid transfer
ACX61_02050	COG0598	Magnesium transport protein CorA
ACX61_02060	COG0494	nUDIX hydrolase
ACX61_02065	COG1040	competence protein
ACX61_02070	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ACX61_02090	COG1946	Acyl-CoA thioesterase
ACX61_02095	COG1301	dicarboxylic acid transport
ACX61_02110	COG1959	2 iron, 2 sulfur cluster binding
ACX61_02115	COG1017	nitric oxide dioxygenase activity
ACX61_02115	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACX61_02120	COG0433	COG0433 Predicted ATPase
ACX61_02125	COG0626	cystathionine gamma-synthase activity
ACX61_02245	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ACX61_02255	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ACX61_02280	COG1960	acyl-CoA dehydrogenase activity
ACX61_02285	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ACX61_02315	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
ACX61_02320	COG0339	signal peptide processing
ACX61_02325	COG0557	exoribonuclease II activity
ACX61_02370	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACX61_02375	COG2169	Transcriptional regulator
ACX61_02380	COG0697	spore germination
ACX61_02385	COG1295	ribonuclease BN
ACX61_02420	COG1702	phosphate starvation-inducible protein PhoH
ACX61_02430	COG0739	heme binding
ACX61_02430	COG0741	lytic transglycosylase activity
ACX61_02430	COG1196	nuclear chromosome segregation
ACX61_02460	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ACX61_02465	COG1183	phosphatidylcholine synthase activity
ACX61_02510	COG1960	acyl-CoA dehydrogenase activity
ACX61_02525	COG2969	positive regulation of protein catabolic process
ACX61_02535	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ACX61_02545	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ACX61_02550	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ACX61_02555	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ACX61_02575	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ACX61_02585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACX61_02590	COG1408	metallophosphoesterase
ACX61_02600	COG2199	diguanylate cyclase activity
ACX61_02645	COG3453	Protein conserved in bacteria
ACX61_02645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACX61_02660	COG1607	acyl-coa hydrolase
ACX61_02690	COG2350	Protein conserved in bacteria
ACX61_02700	COG0613	PHP domain protein
ACX61_02705	COG3781	membrane
ACX61_02715	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ACX61_02720	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACX61_02730	COG1862	Preprotein translocase
ACX61_02765	COG2205	protein histidine kinase activity
ACX61_02770	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ACX61_02790	COG0726	polysaccharide deacetylase
ACX61_02795	COG0463	Glycosyl transferase, family 2
ACX61_02800	COG0438	transferase activity, transferring glycosyl groups
ACX61_02815	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ACX61_02825	COG2826	transposase and inactivated derivatives, IS30 family
ACX61_02835	COG2826	transposase and inactivated derivatives, IS30 family
ACX61_02880	COG1960	acyl-CoA dehydrogenase activity
ACX61_02885	COG1960	acyl-CoA dehydrogenase activity
ACX61_02895	COG2205	protein histidine kinase activity
ACX61_02900	COG0745	RESPONSE REGULATOR receiver
ACX61_02905	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ACX61_02920	COG0584	glycerophosphoryl diester phosphodiesterase
ACX61_02925	COG2096	Adenosyltransferase
ACX61_02930	COG4206	TonB-dependent receptor
ACX61_02940	COG0133	tryptophan synthase activity
ACX61_02975	COG0285	dihydrofolate synthase activity
ACX61_02995	COG0450	alkyl hydroperoxide reductase
ACX61_03010	COG0477	Major facilitator Superfamily
ACX61_03015	COG1272	protein, Hemolysin III
ACX61_03045	COG0183	Belongs to the thiolase family
ACX61_03050	COG2207	Transcriptional regulator
ACX61_03070	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACX61_03090	COG0183	Belongs to the thiolase family
ACX61_03100	COG2885	chlorophyll binding
ACX61_03100	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ACX61_03110	COG1690	Belongs to the RtcB family
ACX61_03115	COG0833	amino acid
ACX61_03125	COG2233	PERMEase
ACX61_03155	COG2094	Belongs to the DNA glycosylase MPG family
ACX61_03160	COG4772	TonB-dependent receptor
ACX61_03165	COG1902	pentaerythritol trinitrate reductase activity
ACX61_03170	COG0679	Auxin Efflux Carrier
ACX61_03180	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACX61_03185	COG0354	folic acid binding
ACX61_03195	COG3189	MarR family transcriptional regulator
ACX61_03200	COG2824	Alkylphosphonate utilization operon protein PhnA
ACX61_03205	COG3422	double-strand break repair
ACX61_03245	COG0840	transmembrane signaling receptor activity
ACX61_03265	COG5510	response to toxic substance
ACX61_03275	COG2832	Protein of unknown function (DUF454)
ACX61_03280	COG1376	ErfK ybiS ycfS ynhG family protein
ACX61_03330	COG1289	transmembrane transporter activity
ACX61_03335	COG2814	Major facilitator Superfamily
ACX61_03350	COG1115	amino acid carrier protein
ACX61_03355	COG1752	Esterase of the alpha-beta hydrolase superfamily
ACX61_03360	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACX61_03365	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
ACX61_03370	COG3590	peptidase
ACX61_03395	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACX61_03405	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACX61_03410	COG1077	Cell shape determining protein MreB Mrl
ACX61_03415	COG1792	Involved in formation and maintenance of cell shape
ACX61_03420	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ACX61_03425	COG0424	maF-like protein
ACX61_03430	COG1530	ribonuclease E activity
ACX61_03440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACX61_03460	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACX61_03485	COG2207	Transcriptional regulator
ACX61_03515	COG2826	transposase and inactivated derivatives, IS30 family
ACX61_03535	COG1113	amino acid transport
ACX61_03540	COG2828	Protein conserved in bacteria
ACX61_03545	COG0142	geranyltranstransferase activity
ACX61_03550	COG2315	Protein conserved in bacteria
ACX61_03565	COG1752	Esterase of the alpha-beta hydrolase superfamily
ACX61_03585	COG2194	sulfuric ester hydrolase activity
ACX61_03590	COG0745	RESPONSE REGULATOR receiver
ACX61_03595	COG0642	Histidine kinase
ACX61_03605	COG0004	ammonium transporteR
ACX61_03610	COG0583	DNA-binding transcription factor activity
ACX61_03625	COG2226	methyltransferase
ACX61_03630	COG0525	valine-tRNA ligase activity
ACX61_03640	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_03650	COG0393	Putative heavy-metal-binding
ACX61_03655	COG0393	Putative heavy-metal-binding
ACX61_03660	COG1538	Outer membrane efflux protein
ACX61_03670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACX61_03675	COG0671	phosphoesterase, PA-phosphatase related
ACX61_03705	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ACX61_03720	COG1648	precorrin-2 dehydrogenase activity
ACX61_03720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACX61_03725	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ACX61_03740	COG0531	amino acid
ACX61_03755	COG0321	lipoyl(octanoyl) transferase activity
ACX61_03760	COG2921	Belongs to the UPF0250 family
ACX61_03795	COG2009	succinate dehydrogenase
ACX61_03800	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ACX61_03805	COG1053	succinate dehydrogenase
ACX61_03810	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ACX61_03825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACX61_03845	COG2354	Protein conserved in bacteria
ACX61_03850	COG2321	neutral zinc metallopeptidase
ACX61_03870	COG2843	Capsule synthesis protein
ACX61_03885	COG0589	response to stress
ACX61_03895	COG0251	oxidation-reduction process
ACX61_03900	COG1309	transcriptional regulator
ACX61_03915	COG0505	Belongs to the CarA family
ACX61_03940	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACX61_03945	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ACX61_03995	COG0477	Major facilitator Superfamily
ACX61_04000	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ACX61_04020	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ACX61_04045	COG0584	glycerophosphoryl diester phosphodiesterase
ACX61_04065	COG0741	lytic transglycosylase activity
ACX61_04085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACX61_04095	COG0582	viral genome integration into host DNA
ACX61_04120	COG2217	Heavy metal translocating P-type atpase
ACX61_04125	COG2205	protein histidine kinase activity
ACX61_04140	COG2132	Multicopper oxidase
ACX61_04170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACX61_04185	COG0778	Nitroreductase
ACX61_04200	COG1929	Belongs to the glycerate kinase type-1 family
ACX61_04205	COG0243	molybdopterin cofactor binding
ACX61_04210	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ACX61_04215	COG3339	Conserved Protein
ACX61_04225	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ACX61_04250	COG1115	amino acid carrier protein
ACX61_04255	COG1113	amino acid transport
ACX61_04265	COG0019	diaminopimelate decarboxylase activity
ACX61_04275	COG2267	carboxylic ester hydrolase activity
ACX61_04280	COG1280	lysine exporter protein (LysE YggA)
ACX61_04285	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ACX61_04315	COG0463	Glycosyl transferase, family 2
ACX61_04335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACX61_04365	COG4591	ABC-type transport system involved in lipoprotein release permease component
ACX61_04370	COG1136	(ABC) transporter
ACX61_04375	COG2333	competence protein COMEC
ACX61_04375	COG0658	competence protein
ACX61_04385	COG0616	signal peptide processing
ACX61_04385	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ACX61_04390	COG0596	Alpha beta hydrolase
ACX61_04395	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ACX61_04405	COG0628	permease
ACX61_04440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACX61_04460	COG0823	Involved in the tonB-independent uptake of proteins
ACX61_04480	COG0824	Thioesterase
ACX61_04485	COG1473	amidohydrolase
ACX61_04505	COG0047	phosphoribosylformylglycinamidine synthase activity
ACX61_04505	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACX61_04510	COG2814	Major facilitator Superfamily
ACX61_04520	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ACX61_04525	COG1024	Enoyl-CoA hydratase
ACX61_04530	COG1056	cytidyltransferase-related domain
ACX61_04530	COG1051	belongs to the nudix hydrolase family
ACX61_04540	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACX61_04555	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ACX61_04570	COG4625	pathogenesis
ACX61_04575	COG0583	DNA-binding transcription factor activity
ACX61_04580	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ACX61_04585	COG4208	sulfate ABC transporter
ACX61_04590	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ACX61_04600	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ACX61_04605	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACX61_04610	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ACX61_04630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACX61_04645	COG0681	Belongs to the peptidase S26 family
ACX61_04660	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ACX61_04670	COG1381	Involved in DNA repair and RecF pathway recombination
ACX61_04675	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ACX61_04685	COG4221	oxidoreductase activity
ACX61_04710	COG0443	Heat shock 70 kDa protein
ACX61_04740	COG0556	nucleotide-excision repair
ACX61_04795	COG2070	2-Nitropropane dioxygenase
ACX61_04825	COG1215	transferase activity, transferring glycosyl groups
ACX61_04840	COG0415	Belongs to the DNA photolyase family
ACX61_04850	COG1252	NADH dehydrogenase
ACX61_04855	COG1686	Belongs to the peptidase S11 family
ACX61_04870	COG1187	pseudouridine synthase activity
ACX61_04890	COG0477	Major facilitator Superfamily
ACX61_04895	COG0583	DNA-binding transcription factor activity
ACX61_04910	COG0612	Peptidase, M16
ACX61_04935	COG0352	thiamine-phosphate diphosphorylase activity
ACX61_04970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACX61_04985	COG1309	transcriptional regulator
ACX61_04995	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ACX61_05000	COG0076	glutamate decarboxylase activity
ACX61_05010	COG1522	sequence-specific DNA binding
ACX61_05015	COG3961	Belongs to the TPP enzyme family
ACX61_05020	COG1113	amino acid transport
ACX61_05025	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ACX61_05030	COG0573	inorganic phosphate transmembrane transporter activity
ACX61_05040	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ACX61_05045	COG0616	signal peptide processing
ACX61_05080	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ACX61_05085	COG1686	Belongs to the peptidase S11 family
ACX61_05110	COG0583	DNA-binding transcription factor activity
ACX61_05115	COG1067	ATP-dependent peptidase activity
ACX61_05140	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ACX61_05160	COG1966	Carbon starvation protein
ACX61_05165	COG2879	small protein
ACX61_05205	COG1741	Belongs to the pirin family
ACX61_05215	COG2964	Protein conserved in bacteria
ACX61_05230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACX61_05235	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACX61_05240	COG4605	iron ion homeostasis
ACX61_05245	COG4604	ABC transporter, ATP-binding protein
ACX61_05250	COG4607	ABC-type enterochelin transport system periplasmic component
ACX61_05255	COG4774	siderophore transport
ACX61_05265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACX61_05270	COG1021	2,3-dihydroxybenzoate-AMP ligase
ACX61_05275	COG1535	isochorismatase
ACX61_05275	COG3433	isochorismatase activity
ACX61_05290	COG1132	(ABC) transporter
ACX61_05295	COG5265	(ABC) transporter
ACX61_05300	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
ACX61_05310	COG1169	isochorismate synthase
ACX61_05325	COG3739	integral membrane protein
ACX61_05355	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ACX61_05385	COG0308	aminopeptidase N
ACX61_05390	COG0512	Glutamine amidotransferase of anthranilate synthase
ACX61_05400	COG3104	oligopeptide transport
ACX61_05415	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ACX61_05450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ACX61_05455	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ACX61_05460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACX61_05480	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ACX61_05485	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ACX61_05490	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ACX61_05505	COG1960	acyl-CoA dehydrogenase activity
ACX61_05510	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACX61_05515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACX61_05530	COG2223	nitrite transmembrane transporter activity
ACX61_05540	COG0024	Methionine aminopeptidase
ACX61_05545	COG0052	Belongs to the universal ribosomal protein uS2 family
ACX61_05560	COG2207	Transcriptional regulator
ACX61_05585	COG2951	lytic endotransglycosylase activity
ACX61_05590	COG0772	Belongs to the SEDS family
ACX61_05605	COG0842	Transport permease protein
ACX61_05610	COG1131	(ABC) transporter
ACX61_05615	COG0582	viral genome integration into host DNA
ACX61_05720	COG0305	Participates in initiation and elongation during chromosome replication
ACX61_05815	COG5410	chromosome segregation
ACX61_05990	COG1538	Outer membrane efflux protein
ACX61_06000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACX61_06010	COG2826	transposase and inactivated derivatives, IS30 family
ACX61_06020	COG4215	(ABC) transporter
ACX61_06025	COG4160	amino acid transport
ACX61_06030	COG4598	ABC transporter
ACX61_06040	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACX61_06050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACX61_06055	COG0384	phenazine biosynthesis protein PhzF
ACX61_06065	COG1720	tRNA m6t6A37 methyltransferase activity
ACX61_06085	COG0745	RESPONSE REGULATOR receiver
ACX61_06090	COG0642	Histidine kinase
ACX61_06100	COG0494	nUDIX hydrolase
ACX61_06110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACX61_06115	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ACX61_06120	COG3139	Protein of unknown function (DUF1315)
ACX61_06130	COG1301	dicarboxylic acid transport
ACX61_06135	COG1960	acyl-CoA dehydrogenase activity
ACX61_06150	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ACX61_06160	COG2195	Cleaves the N-terminal amino acid of tripeptides
ACX61_06180	COG1690	Belongs to the RtcB family
ACX61_06185	COG1234	tRNA 3'-trailer cleavage
ACX61_06190	COG4650	regulator
ACX61_06220	COG2363	Small membrane protein
ACX61_06240	COG0513	Belongs to the DEAD box helicase family
ACX61_06250	COG0778	Nitroreductase
ACX61_06390	COG1286	toxin biosynthetic process
ACX61_06415	COG4783	chaperone-mediated protein folding
ACX61_06420	COG1610	YqeY-like protein
ACX61_06425	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ACX61_06520	COG3111	PFAM Bacterial OB fold (BOF) protein
ACX61_06545	COG3243	poly(R)-hydroxyalkanoic acid synthase
ACX61_06550	COG0786	glutamate:sodium symporter activity
ACX61_06560	COG2186	Transcriptional regulator
ACX61_06565	COG1051	belongs to the nudix hydrolase family
ACX61_06595	COG2995	paraquat-inducible protein a
ACX61_06600	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ACX61_06600	COG3008	intermembrane lipid transfer
ACX61_06610	COG2351	hydroxyisourate hydrolase activity
ACX61_06650	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACX61_06660	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACX61_06665	COG0642	Histidine kinase
ACX61_06670	COG0745	RESPONSE REGULATOR receiver
ACX61_06690	COG1794	racemase activity, acting on amino acids and derivatives
ACX61_06720	COG1301	dicarboxylic acid transport
ACX61_06730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACX61_06735	COG2011	ABC-type metal ion transport system permease component
ACX61_06740	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ACX61_06745	COG1464	Belongs to the NlpA lipoprotein family
ACX61_06750	COG0151	Belongs to the GarS family
ACX61_06755	COG0138	bifunctional purine biosynthesis protein purh
ACX61_06760	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ACX61_06790	COG2308	Evidence 4 Homologs of previously reported genes of
ACX61_06800	COG1305	Transglutaminase-like
ACX61_06810	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ACX61_06815	COG0305	Participates in initiation and elongation during chromosome replication
ACX61_06840	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ACX61_06850	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACX61_06855	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ACX61_06880	COG1649	PFAM Uncharacterised BCR, COG1649
ACX61_06880	COG0726	polysaccharide deacetylase
ACX61_06885	COG1215	transferase activity, transferring glycosyl groups
ACX61_06890	COG3658	cytochrome
ACX61_06900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACX61_06920	COG0583	DNA-binding transcription factor activity
ACX61_06950	COG1960	acyl-CoA dehydrogenase activity
ACX61_06955	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACX61_06960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACX61_06985	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ACX61_06990	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ACX61_06995	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ACX61_07000	COG2205	protein histidine kinase activity
ACX61_07005	COG0745	RESPONSE REGULATOR receiver
ACX61_07010	COG0174	glutamine synthetase
ACX61_07030	COG0729	surface antigen
ACX61_07150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACX61_07155	COG2814	Major facilitator Superfamily
ACX61_07170	COG0583	DNA-binding transcription factor activity
ACX61_07185	COG1187	pseudouridine synthase activity
ACX61_07205	COG0802	atpase or kinase
ACX61_07210	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ACX61_07220	COG1923	regulation of RNA biosynthetic process
ACX61_07225	COG0697	spore germination
ACX61_07240	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACX61_07255	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACX61_07255	COG0519	Catalyzes the synthesis of GMP from XMP
ACX61_07260	COG4302	ethanolamine ammonia-lyase activity
ACX61_07265	COG4303	Ethanolamine ammonia lyase large subunit
ACX61_07270	COG0531	amino acid
ACX61_07290	COG1454	alcohol dehydrogenase
ACX61_07295	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ACX61_07320	COG0308	aminopeptidase N
ACX61_07360	COG1605	Chorismate mutase
ACX61_07375	COG1309	transcriptional regulator
ACX61_07385	COG0668	transmembrane transport
ACX61_07415	COG3328	transposase activity
ACX61_07425	COG4773	Receptor
ACX61_07445	COG0488	(ABC) transporter
ACX61_07450	COG0589	response to stress
ACX61_07470	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ACX61_07480	COG3135	benzoate transporter
ACX61_07485	COG1522	sequence-specific DNA binding
ACX61_07500	COG0583	DNA-binding transcription factor activity
ACX61_07510	COG0183	Belongs to the thiolase family
ACX61_07550	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ACX61_07560	COG0824	Thioesterase
ACX61_07565	COG1454	alcohol dehydrogenase
ACX61_07575	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACX61_07605	COG0069	glutamate synthase activity
ACX61_07755	COG5410	chromosome segregation
ACX61_07855	COG1598	PFAM Uncharacterised protein family UPF0150
ACX61_07905	COG3179	chitinase
ACX61_07915	COG1063	alcohol dehydrogenase
ACX61_07920	COG3293	Transposase
ACX61_07950	COG2814	Major facilitator Superfamily
ACX61_07965	COG0511	ligase activity, forming carbon-carbon bonds
ACX61_07980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ACX61_07980	COG1116	anion transmembrane transporter activity
ACX61_07985	COG0745	RESPONSE REGULATOR receiver
ACX61_07995	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACX61_07995	COG2146	nitrite reductase [NAD(P)H] activity
ACX61_08000	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACX61_08005	COG0243	molybdopterin cofactor binding
ACX61_08020	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACX61_08035	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACX61_08035	COG0315	cyclic pyranopterin monophosphate synthase activity
ACX61_08040	COG0303	'Molybdopterin
ACX61_08050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACX61_08055	COG0697	spore germination
ACX61_08075	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ACX61_08080	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ACX61_08135	COG2204	response regulator
ACX61_08140	COG3852	Histidine kinase
ACX61_08160	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ACX61_08165	COG0575	Belongs to the CDS family
ACX61_08180	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACX61_08200	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACX61_08210	COG2137	regulation of response to DNA damage stimulus
ACX61_08220	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ACX61_08225	COG1011	Hydrolase
ACX61_08250	COG1522	sequence-specific DNA binding
ACX61_08260	COG1113	amino acid transport
ACX61_08275	COG0659	secondary active sulfate transmembrane transporter activity
ACX61_08280	COG2135	peptidase activity
ACX61_08295	COG3300	MHYT domain
ACX61_08295	COG5001	Diguanylate cyclase
ACX61_08310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACX61_08310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACX61_08310	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ACX61_08315	COG1105	Belongs to the carbohydrate kinase PfkB family
ACX61_08320	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACX61_08320	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACX61_08350	COG0024	Methionine aminopeptidase
ACX61_08355	COG0583	DNA-binding transcription factor activity
ACX61_08365	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ACX61_08370	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACX61_08375	COG0516	GMP reductase activity
ACX61_08375	COG0517	IMP dehydrogenase activity
ACX61_08400	COG0552	protein localization to endoplasmic reticulum
ACX61_08410	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
ACX61_08425	COG4890	Cyd operon protein YbgT
ACX61_08430	COG1294	oxidase, subunit
ACX61_08445	COG2826	transposase and inactivated derivatives, IS30 family
ACX61_08450	COG1585	Membrane protein implicated in regulation of membrane protease activity
ACX61_08460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACX61_08465	COG4774	siderophore transport
ACX61_08480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ACX61_08485	COG0569	domain protein
ACX61_08490	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACX61_08530	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ACX61_08535	COG0542	response to heat
ACX61_08545	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACX61_08560	COG1902	pentaerythritol trinitrate reductase activity
ACX61_08560	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACX61_08605	COG2323	membrane
ACX61_08610	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ACX61_08620	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACX61_08625	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACX61_08630	COG0183	Belongs to the thiolase family
ACX61_08635	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ACX61_08640	COG0596	Alpha beta hydrolase
ACX61_08645	COG2271	Major facilitator Superfamily
ACX61_08650	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ACX61_08655	COG3485	protocatechuate 3,4-dioxygenase
ACX61_08660	COG3485	protocatechuate 3,4-dioxygenase
ACX61_08665	COG0710	3-dehydroquinate dehydratase activity
ACX61_08670	COG3420	alginic acid biosynthetic process
ACX61_08675	COG3659	wide pore channel activity
ACX61_08680	COG4993	Dehydrogenase
ACX61_08690	COG2391	methyltransferase activity
ACX61_08705	COG1414	Transcriptional regulator
ACX61_08710	COG0583	DNA-binding transcription factor activity
ACX61_08715	COG1960	acyl-CoA dehydrogenase activity
ACX61_08740	COG2814	Major facilitator Superfamily
ACX61_08750	COG0154	amidase activity
ACX61_08770	COG4638	Rieske (2fe-2S)
ACX61_08780	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_08790	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACX61_08800	COG3733	amine oxidase
ACX61_08810	COG1012	belongs to the aldehyde dehydrogenase family
ACX61_08820	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACX61_08825	COG0183	Belongs to the thiolase family
ACX61_08830	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACX61_08835	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACX61_08845	COG4829	muconolactone delta-isomerase
ACX61_08850	COG4948	Mandelate Racemase Muconate Lactonizing
ACX61_08855	COG0583	DNA-binding transcription factor activity
ACX61_08865	COG2186	Transcriptional regulator
ACX61_08885	COG1012	belongs to the aldehyde dehydrogenase family
ACX61_08900	COG1902	pentaerythritol trinitrate reductase activity
ACX61_08900	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACX61_08940	COG1309	transcriptional regulator
ACX61_08945	COG0583	DNA-binding transcription factor activity
ACX61_08950	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_08955	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_08960	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_08970	COG1960	acyl-CoA dehydrogenase activity
ACX61_08980	COG0318	PFAM AMP-dependent synthetase and ligase
ACX61_09040	COG0583	DNA-binding transcription factor activity
ACX61_09060	COG1566	PFAM secretion protein HlyD family protein
ACX61_09075	COG1012	belongs to the aldehyde dehydrogenase family
ACX61_09080	COG0129	dihydroxy-acid dehydratase activity
ACX61_09090	COG0583	DNA-binding transcription factor activity
ACX61_09095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACX61_09105	COG2084	Dehydrogenase
ACX61_09120	COG1120	ATPase activity
ACX61_09140	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACX61_09190	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ACX61_09245	COG2205	protein histidine kinase activity
ACX61_09265	COG2826	transposase and inactivated derivatives, IS30 family
ACX61_09275	COG3539	Fimbrial protein
ACX61_09300	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ACX61_09310	COG0753	catalase activity
ACX61_09325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACX61_09385	COG1535	isochorismatase
ACX61_09385	COG3433	isochorismatase activity
ACX61_09390	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_09395	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ACX61_09400	COG4149	molybdate abc transporter
ACX61_09405	COG0725	ABC transporter, periplasmic molybdate-binding protein
ACX61_09415	COG4638	Rieske (2fe-2S)
ACX61_09420	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
ACX61_09425	COG0543	2 iron, 2 sulfur cluster binding
ACX61_09425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACX61_09440	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACX61_09455	COG3328	transposase activity
ACX61_09465	COG0412	Dienelactone hydrolase
ACX61_09475	COG2207	Transcriptional regulator
ACX61_09480	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_09485	COG2610	gluconate transmembrane transporter activity
ACX61_09495	COG0583	DNA-binding transcription factor activity
ACX61_09510	COG2031	fatty acid transporter
ACX61_09515	COG0183	Belongs to the thiolase family
ACX61_09520	COG0583	DNA-binding transcription factor activity
ACX61_09525	COG0583	DNA-binding transcription factor activity
ACX61_09540	COG1027	Aspartate ammonia-lyase
ACX61_09550	COG0477	Major facilitator Superfamily
ACX61_09570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACX61_09575	COG4521	taurine ABC transporter
ACX61_09600	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ACX61_09610	COG3708	Transcriptional regulator
ACX61_09610	COG2207	Transcriptional regulator
ACX61_09625	COG0730	response to heat
ACX61_09635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACX61_09635	COG3453	Protein conserved in bacteria
ACX61_09645	COG3781	membrane
ACX61_09650	COG1063	alcohol dehydrogenase
ACX61_09660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACX61_09665	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACX61_09670	COG0022	dehydrogenase e1 component
ACX61_09675	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ACX61_09680	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACX61_09695	COG3706	GGDEF domain
ACX61_09710	COG0133	tryptophan synthase activity
ACX61_09720	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACX61_09755	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ACX61_09790	COG2226	methyltransferase
ACX61_09820	COG0537	adenosine 5'-monophosphoramidase activity
ACX61_09845	COG0842	Transport permease protein
ACX61_09850	COG0842	Transport permease protein
ACX61_09855	COG1131	(ABC) transporter
ACX61_09870	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACX61_09875	COG4773	Receptor
ACX61_09895	COG0730	response to heat
ACX61_09900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACX61_09915	COG0406	alpha-ribazole phosphatase activity
ACX61_09920	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ACX61_09935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACX61_09965	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACX61_09975	COG4264	IucA IucC family
ACX61_09980	COG4264	IucA IucC family
ACX61_09985	COG2814	Major facilitator Superfamily
ACX61_10000	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ACX61_10015	COG1960	acyl-CoA dehydrogenase activity
ACX61_10020	COG1960	acyl-CoA dehydrogenase activity
ACX61_10025	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACX61_10030	COG2207	Transcriptional regulator
ACX61_10035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACX61_10040	COG0776	regulation of translation
ACX61_10065	COG0822	iron-sulfur transferase activity
ACX61_10070	COG0316	Belongs to the HesB IscA family
ACX61_10100	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ACX61_10120	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACX61_10125	COG0702	epimerase
ACX61_10165	COG0601	transmembrane transport
ACX61_10170	COG0339	signal peptide processing
ACX61_10175	COG4166	transmembrane transport
ACX61_10215	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ACX61_10220	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ACX61_10250	COG0776	regulation of translation
ACX61_10270	COG0590	tRNA wobble adenosine to inosine editing
ACX61_10300	COG2165	general secretion pathway protein
ACX61_10315	COG0084	hydrolase, TatD family'
ACX61_10335	COG1663	tetraacyldisaccharide 4'-kinase activity
ACX61_10340	COG1132	(ABC) transporter
ACX61_10350	COG0811	peptide transport
ACX61_10355	COG1475	DNA binding
ACX61_10360	COG1192	Involved in chromosome partitioning
ACX61_10370	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ACX61_10385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACX61_10390	COG0191	fructose-bisphosphate aldolase activity
ACX61_10410	COG0424	maF-like protein
ACX61_10415	COG2850	peptidyl-arginine hydroxylation
ACX61_10425	COG0640	Transcriptional regulator
ACX61_10435	COG3619	membrane
ACX61_10440	COG3122	Protein conserved in bacteria
ACX61_10445	COG3328	transposase activity
ACX61_10450	COG1132	(ABC) transporter
ACX61_10470	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ACX61_10475	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACX61_10485	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ACX61_10485	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ACX61_10485	COG0506	proline dehydrogenase activity
ACX61_10490	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ACX61_10505	COG3698	Phosphodiester glycosidase
ACX61_10515	COG2353	YceI-like domain
ACX61_10525	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ACX61_10570	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ACX61_10570	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACX61_10595	COG3539	Fimbrial protein
ACX61_10600	COG3121	Chaperone
ACX61_10620	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ACX61_10630	COG0583	DNA-binding transcription factor activity
ACX61_10635	COG2826	transposase and inactivated derivatives, IS30 family
ACX61_10655	COG1309	transcriptional regulator
ACX61_10670	COG1522	sequence-specific DNA binding
ACX61_10680	COG1126	abc transporter atp-binding protein
ACX61_10685	COG0765	amino acid transport
ACX61_10690	COG0765	amino acid transport
ACX61_10720	COG1464	Belongs to the NlpA lipoprotein family
ACX61_10730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ACX61_10735	COG2011	ABC-type metal ion transport system permease component
ACX61_10740	COG0012	GTP binding
ACX61_10765	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ACX61_10805	COG0386	Belongs to the glutathione peroxidase family
ACX61_10815	COG0436	Aminotransferase
ACX61_10820	COG1301	dicarboxylic acid transport
ACX61_10855	COG3634	alkyl hydroperoxide reductase activity
ACX61_10870	COG0583	DNA-binding transcription factor activity
ACX61_10875	COG0798	PFAM Bile acid sodium symporter
ACX61_10880	COG0640	Transcriptional regulator
ACX61_10910	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ACX61_10920	COG0583	DNA-binding transcription factor activity
ACX61_10930	COG1953	Uracil, thiamine, allantoin
ACX61_10940	COG2175	clavaminate synthase activity
ACX61_10945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACX61_10950	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ACX61_10955	COG4521	taurine ABC transporter
ACX61_10965	COG0477	Major facilitator Superfamily
ACX61_10985	COG1271	oxidase subunit
ACX61_10990	COG1294	oxidase, subunit
ACX61_11000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACX61_11020	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ACX61_11040	COG3052	prosthetic group binding
ACX61_11045	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
ACX61_11055	COG2814	Major facilitator Superfamily
ACX61_11070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACX61_11075	COG1346	cytolysis
ACX61_11085	COG0583	DNA-binding transcription factor activity
ACX61_11090	COG0625	glutathione transferase activity
ACX61_11095	COG0625	glutathione transferase activity
ACX61_11100	COG0583	DNA-binding transcription factor activity
ACX61_11105	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_11115	COG1045	serine acetyltransferase
ACX61_11120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACX61_11125	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACX61_11130	COG1280	lysine exporter protein (LysE YggA)
ACX61_11140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACX61_11145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACX61_11150	COG1126	abc transporter atp-binding protein
ACX61_11155	COG0765	amino acid transport
ACX61_11160	COG0765	amino acid transport
ACX61_11175	COG0784	Response regulator, receiver
ACX61_11175	COG2205	protein histidine kinase activity
ACX61_11195	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACX61_11215	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_11265	COG0583	DNA-binding transcription factor activity
ACX61_11285	COG0318	PFAM AMP-dependent synthetase and ligase
ACX61_11290	COG1309	transcriptional regulator
ACX61_11295	COG1960	acyl-CoA dehydrogenase activity
ACX61_11300	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACX61_11305	COG1024	Enoyl-CoA hydratase
ACX61_11320	COG0583	DNA-binding transcription factor activity
ACX61_11335	COG1960	acyl-CoA dehydrogenase activity
ACX61_11345	COG2814	Major facilitator Superfamily
ACX61_11355	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACX61_11360	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACX61_11365	COG2814	Major facilitator Superfamily
ACX61_11370	COG1960	acyl-CoA dehydrogenase activity
ACX61_11375	COG1024	Enoyl-CoA hydratase
ACX61_11380	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_11385	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACX61_11390	COG0183	Belongs to the thiolase family
ACX61_11400	COG2814	Major facilitator Superfamily
ACX61_11410	COG1024	Enoyl-CoA hydratase
ACX61_11425	COG1960	acyl-CoA dehydrogenase activity
ACX61_11430	COG2814	Major facilitator Superfamily
ACX61_11435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACX61_11440	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ACX61_11455	COG3842	ATPase activity
ACX61_11460	COG1840	ABC-type Fe3 transport system, periplasmic component
ACX61_11475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACX61_11480	COG1414	Transcriptional regulator
ACX61_11490	COG0583	DNA-binding transcription factor activity
ACX61_11495	COG3038	cytochrome b561
ACX61_11500	COG0753	catalase activity
ACX61_11535	COG0406	alpha-ribazole phosphatase activity
ACX61_11540	COG3328	transposase activity
ACX61_11550	COG2050	protein possibly involved in aromatic compounds catabolism
ACX61_11560	COG3327	negative regulation of DNA-templated transcription, initiation
ACX61_11565	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ACX61_11570	COG0183	Belongs to the thiolase family
ACX61_11575	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACX61_11580	COG1024	Enoyl-CoA hydratase
ACX61_11585	COG1024	Enoyl-CoA hydratase
ACX61_11590	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACX61_11595	COG2151	metal-sulfur cluster biosynthetic enzyme
ACX61_11600	COG3396	Phenylacetate-CoA oxygenase
ACX61_11605	COG3460	Phenylacetate-CoA oxygenase
ACX61_11610	COG3396	Phenylacetate-CoA oxygenase
ACX61_11615	COG1012	belongs to the aldehyde dehydrogenase family
ACX61_11615	COG2030	dehydratase
ACX61_11620	COG1760	l-serine dehydratase
ACX61_11625	COG0531	amino acid
ACX61_11630	COG1012	belongs to the aldehyde dehydrogenase family
ACX61_11675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACX61_11690	COG0789	Transcriptional regulator
ACX61_11700	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACX61_11715	COG2807	transmembrane transport
ACX61_11720	COG0590	tRNA wobble adenosine to inosine editing
ACX61_11730	COG0583	DNA-binding transcription factor activity
ACX61_11770	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ACX61_11770	COG2885	chlorophyll binding
ACX61_11885	COG1116	anion transmembrane transporter activity
ACX61_11890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACX61_11900	COG0864	Transcriptional regulator
ACX61_11915	COG1733	regulation of RNA biosynthetic process
ACX61_11920	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACX61_11925	COG0439	Biotin carboxylase
ACX61_11940	COG1063	alcohol dehydrogenase
ACX61_11950	COG1309	transcriptional regulator
ACX61_11955	COG3328	transposase activity
ACX61_11970	COG0038	chloride channel
ACX61_11975	COG4770	biotin carboxylase activity
ACX61_11995	COG1914	H( )-stimulated, divalent metal cation uptake system
ACX61_12000	COG0583	DNA-binding transcription factor activity
ACX61_12015	COG2826	transposase and inactivated derivatives, IS30 family
ACX61_12035	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACX61_12055	COG2814	Major facilitator Superfamily
ACX61_12065	COG1560	Kdo2-lipid A biosynthetic process
ACX61_12075	COG5006	permease, DMT superfamily
ACX61_12080	COG1522	sequence-specific DNA binding
ACX61_12095	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ACX61_12140	COG1137	ATPase activity
ACX61_12145	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ACX61_12155	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ACX61_12185	COG2826	transposase and inactivated derivatives, IS30 family
ACX61_12205	COG1733	regulation of RNA biosynthetic process
ACX61_12210	COG2814	Major facilitator Superfamily
ACX61_12240	COG1278	Cold shock
ACX61_12245	COG1280	lysine exporter protein (LysE YggA)
ACX61_12275	COG1570	exodeoxyribonuclease VII activity
ACX61_12325	COG0583	DNA-binding transcription factor activity
ACX61_12330	COG4638	Rieske (2fe-2S)
ACX61_12335	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
ACX61_12340	COG0543	2 iron, 2 sulfur cluster binding
ACX61_12340	COG0633	Ferredoxin
ACX61_12345	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_12350	COG3135	benzoate transporter
ACX61_12355	COG2814	Major facilitator Superfamily
ACX61_12370	COG1643	Atp-dependent helicase
ACX61_12375	COG0450	alkyl hydroperoxide reductase
ACX61_12385	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ACX61_12395	COG3634	alkyl hydroperoxide reductase activity
ACX61_12415	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ACX61_12435	COG0625	glutathione transferase activity
ACX61_12445	COG2885	chlorophyll binding
ACX61_12495	COG3328	transposase activity
ACX61_12500	COG1765	OsmC-like protein
ACX61_12510	COG0667	Aldo Keto reductase
ACX61_12525	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ACX61_12535	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ACX61_12545	COG0582	viral genome integration into host DNA
ACX61_12555	COG2826	transposase and inactivated derivatives, IS30 family
ACX61_12575	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACX61_12655	COG0592	DNA-directed DNA polymerase activity
ACX61_12835	COG3755	Protein conserved in bacteria
ACX61_12880	COG1484	DNA-dependent DNA replication
ACX61_12975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACX61_13025	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ACX61_13035	COG3038	cytochrome b561
ACX61_13040	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ACX61_13045	COG2252	PERMEase
ACX61_13055	COG2072	flavoprotein involved in K transport
ACX61_13070	COG1741	Belongs to the pirin family
ACX61_13075	COG1309	transcriptional regulator
ACX61_13085	COG0300	oxidoreductase activity
ACX61_13090	COG2072	flavoprotein involved in K transport
ACX61_13095	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ACX61_13155	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACX61_13170	COG2814	Major facilitator Superfamily
ACX61_13175	COG1024	Enoyl-CoA hydratase
ACX61_13180	COG1012	belongs to the aldehyde dehydrogenase family
ACX61_13190	COG1960	acyl-CoA dehydrogenase activity
ACX61_13215	COG2186	Transcriptional regulator
ACX61_13220	COG1012	belongs to the aldehyde dehydrogenase family
ACX61_13230	COG4948	Mandelate Racemase Muconate Lactonizing
ACX61_13235	COG2271	Major facilitator Superfamily
ACX61_13240	COG2721	sulfolactate sulfo-lyase activity
ACX61_13245	COG0697	spore germination
ACX61_13270	COG1113	amino acid transport
ACX61_13290	COG1012	belongs to the aldehyde dehydrogenase family
ACX61_13320	COG1113	amino acid transport
ACX61_13355	COG2826	transposase and inactivated derivatives, IS30 family
ACX61_13385	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ACX61_13385	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ACX61_13410	COG0514	ATP-dependent DNA helicase (RecQ)
ACX61_13510	COG2161	toxin-antitoxin pair type II binding
ACX61_13520	COG3328	transposase activity
ACX61_13530	COG0582	viral genome integration into host DNA
ACX61_13540	COG1902	pentaerythritol trinitrate reductase activity
ACX61_13540	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACX61_13550	COG5001	Diguanylate cyclase
ACX61_13550	COG4251	negative regulation of phosphorylation
ACX61_13550	COG3706	GGDEF domain
ACX61_13550	COG2203	Gaf domain
ACX61_13560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACX61_13580	COG4172	Belongs to the ABC transporter superfamily
ACX61_13585	COG4239	(ABC) transporter, permease
ACX61_13590	COG4174	ABC transporter (Permease)
ACX61_13600	COG0741	lytic transglycosylase activity
ACX61_13600	COG1388	LysM domain
ACX61_13605	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACX61_13645	COG0583	DNA-binding transcription factor activity
ACX61_13650	COG1279	arginine transmembrane transporter activity
ACX61_13670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACX61_13675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACX61_13680	COG0006	proline dipeptidase activity
ACX61_13705	COG2194	sulfuric ester hydrolase activity
ACX61_13820	COG3620	sequence-specific DNA binding
ACX61_13865	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ACX61_13880	COG3384	dioxygenase
ACX61_13890	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ACX61_13895	COG2878	Part of a membrane complex involved in electron transport
ACX61_13900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ACX61_13920	COG0768	penicillin binding
ACX61_13925	COG0742	ribosomal rna small subunit methyltransferase
ACX61_13940	COG0830	nickel cation binding
ACX61_13950	COG0804	urea catabolic process
ACX61_13990	COG1253	flavin adenine dinucleotide binding
ACX61_13995	COG2851	Citrate transporter
ACX61_14040	COG1773	rubredoxin
ACX61_14045	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACX61_14055	COG0583	DNA-binding transcription factor activity
ACX61_14080	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ACX61_14085	COG4181	ATPase activity
ACX61_14130	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACX61_14150	COG0306	phosphate transporter
ACX61_14180	COG2223	nitrite transmembrane transporter activity
ACX61_14185	COG2207	Transcriptional regulator
ACX61_14190	COG2066	Belongs to the glutaminase family
ACX61_14195	COG0242	peptide deformylase activity
ACX61_14200	COG0477	Major facilitator Superfamily
ACX61_14210	COG0028	Belongs to the TPP enzyme family
ACX61_14225	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_14230	COG2267	carboxylic ester hydrolase activity
ACX61_14240	COG2271	Major facilitator Superfamily
ACX61_14255	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_14275	COG1414	Transcriptional regulator
ACX61_14290	COG1024	Enoyl-CoA hydratase
ACX61_14300	COG1215	transferase activity, transferring glycosyl groups
ACX61_14305	COG1649	PFAM Uncharacterised BCR, COG1649
ACX61_14305	COG0726	polysaccharide deacetylase
ACX61_14315	COG4681	YaeQ
ACX61_14325	COG0523	cobalamin synthesis protein
ACX61_14335	COG1607	acyl-coa hydrolase
ACX61_14345	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACX61_14350	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACX61_14355	COG1309	transcriptional regulator
ACX61_14380	COG2040	homocysteine
ACX61_14385	COG0531	amino acid
ACX61_14440	COG1595	DNA-templated transcription, initiation
ACX61_14450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACX61_14455	COG0477	Major facilitator Superfamily
ACX61_14480	COG0405	Gamma-glutamyltransferase
ACX61_14485	COG2814	Major facilitator Superfamily
ACX61_14495	COG2050	protein possibly involved in aromatic compounds catabolism
ACX61_14510	COG1090	epimerase
ACX61_14530	COG0420	3'-5' exonuclease activity
ACX61_14555	COG0735	belongs to the Fur family
ACX61_14560	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACX61_14580	COG0121	glutamine amidotransferase
ACX61_14595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACX61_14605	COG0210	DNA helicase
ACX61_14610	COG2885	chlorophyll binding
ACX61_14615	COG0204	Acyl-transferase
ACX61_14630	COG2894	cell division
ACX61_14645	COG1280	lysine exporter protein (LysE YggA)
ACX61_14650	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ACX61_14650	COG1674	ftsk spoiiie
ACX61_14655	COG0492	ferredoxin-NADP+ reductase activity
ACX61_14660	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ACX61_14670	COG0456	acetyltransferase
ACX61_14730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACX61_14730	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ACX61_14750	COG1012	belongs to the aldehyde dehydrogenase family
ACX61_14770	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACX61_14795	COG0564	pseudouridine synthase activity
ACX61_14805	COG0358	DNA primase activity
ACX61_14820	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ACX61_14850	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACX61_14880	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACX61_14890	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ACX61_14890	COG0352	thiamine-phosphate diphosphorylase activity
ACX61_14890	COG0351	phosphomethylpyrimidine kinase
ACX61_14895	COG1652	LysM domain
ACX61_14920	COG1399	metal-binding, possibly nucleic acid-binding protein
ACX61_14925	COG3101	peptidyl-lysine hydroxylation
ACX61_14930	COG0009	L-threonylcarbamoyladenylate synthase
ACX61_14935	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ACX61_14940	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ACX61_14955	COG4106	trans-aconitate 2-methyltransferase activity
ACX61_14970	COG2226	methyltransferase
ACX61_14970	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACX61_14970	COG0596	Alpha beta hydrolase
ACX61_14975	COG1877	trehalose-phosphatase activity
ACX61_14980	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ACX61_14985	COG2223	nitrite transmembrane transporter activity
ACX61_15005	COG1196	nuclear chromosome segregation
ACX61_15015	COG0730	response to heat
ACX61_15030	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACX61_15040	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACX61_15090	COG0489	protein tyrosine kinase activity
ACX61_15100	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACX61_15100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACX61_15130	COG2515	1-aminocyclopropane-1-carboxylate deaminase
ACX61_15135	COG2081	HI0933 family
ACX61_15145	COG0668	transmembrane transport
ACX61_15165	COG0583	DNA-binding transcription factor activity
ACX61_15185	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACX61_15190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACX61_15220	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ACX61_15255	COG2205	protein histidine kinase activity
ACX61_15260	COG0745	RESPONSE REGULATOR receiver
ACX61_15280	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACX61_15295	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACX61_15300	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ACX61_15310	COG0583	DNA-binding transcription factor activity
ACX61_15340	COG0583	DNA-binding transcription factor activity
ACX61_15355	COG0583	DNA-binding transcription factor activity
ACX61_15360	COG1053	succinate dehydrogenase
ACX61_15370	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ACX61_15375	COG2814	Major facilitator Superfamily
ACX61_15380	COG1960	acyl-CoA dehydrogenase activity
ACX61_15385	COG0583	DNA-binding transcription factor activity
ACX61_15390	COG1063	alcohol dehydrogenase
ACX61_15420	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ACX61_15425	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ACX61_15430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACX61_15445	COG3667	copper resistance
ACX61_15450	COG2132	Multicopper oxidase
ACX61_15460	COG0561	phosphatase activity
ACX61_15465	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ACX61_15475	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ACX61_15490	COG1214	PFAM Peptidase M22, glycoprotease
ACX61_15515	COG3328	transposase activity
ACX61_15525	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACX61_15535	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ACX61_15540	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ACX61_15545	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACX61_15605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACX61_15615	COG1846	Transcriptional regulator
ACX61_15620	COG1764	response to oxidative stress
ACX61_15660	COG0037	tRNA processing
ACX61_15670	COG0248	Ppx GppA phosphatase
ACX61_15695	COG0072	phenylalanine-tRNA ligase activity
ACX61_15720	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ACX61_15735	COG1238	metal cluster binding
ACX61_15740	COG0625	glutathione transferase activity
ACX61_15755	COG0318	PFAM AMP-dependent synthetase and ligase
ACX61_15760	COG3028	Belongs to the UPF0307 family
ACX61_15765	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACX61_15785	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACX61_15790	COG0617	tRNA 3'-terminal CCA addition
ACX61_15795	COG1555	photosystem II stabilization
ACX61_15800	COG3956	TIGRFAM MazG family protein
ACX61_15810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACX61_15830	COG5002	protein histidine kinase activity
ACX61_15830	COG2205	protein histidine kinase activity
ACX61_15830	COG0784	Response regulator, receiver
ACX61_15835	COG1024	Enoyl-CoA hydratase
ACX61_15840	COG2084	Dehydrogenase
ACX61_15845	COG3622	Belongs to the hyi family
ACX61_15860	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ACX61_15865	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ACX61_15870	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ACX61_15875	COG0697	spore germination
ACX61_15885	COG2814	Major facilitator Superfamily
ACX61_15890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACX61_15900	COG0583	DNA-binding transcription factor activity
ACX61_15905	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ACX61_15915	COG0084	hydrolase, TatD family'
ACX61_15930	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ACX61_15935	COG2801	Transposase and inactivated derivatives
ACX61_15955	COG2130	NADP-dependent
ACX61_15960	COG1309	transcriptional regulator
ACX61_15970	COG1902	pentaerythritol trinitrate reductase activity
ACX61_15980	COG1979	alcohol dehydrogenase
ACX61_15990	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ACX61_16005	COG0604	alcohol dehydrogenase
ACX61_16005	COG3321	synthase
ACX61_16010	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ACX61_16015	COG0583	DNA-binding transcription factor activity
ACX61_16020	COG4221	oxidoreductase activity
ACX61_16060	COG2826	transposase and inactivated derivatives, IS30 family
ACX61_16085	COG0440	acetolactate synthase activity
ACX61_16090	COG0028	Belongs to the TPP enzyme family
ACX61_16115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACX61_16120	COG1136	(ABC) transporter
ACX61_16120	COG0577	efflux transmembrane transporter activity
ACX61_16125	COG1538	Outer membrane efflux protein
ACX61_16140	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ACX61_16145	COG1162	GTPase activity
ACX61_16155	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ACX61_16195	COG1426	Protein conserved in bacteria
ACX61_16230	COG0793	Belongs to the peptidase S41A family
ACX61_16245	COG2267	carboxylic ester hydrolase activity
ACX61_16255	COG1012	belongs to the aldehyde dehydrogenase family
ACX61_16260	COG3265	gluconokinase activity
ACX61_16270	COG0800	Aldolase
ACX61_16280	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ACX61_16285	COG0857	belongs to the CobB CobQ family
ACX61_16285	COG0280	phosphate acetyltransferase
ACX61_16290	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ACX61_16290	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ACX61_16310	COG0740	serine-type endopeptidase activity
ACX61_16320	COG4774	siderophore transport
ACX61_16330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACX61_16340	COG2813	Specifically methylates the guanine in position
ACX61_16340	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACX61_16445	COG0788	formyltetrahydrofolate deformylase activity
ACX61_16460	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ACX61_16465	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ACX61_16470	COG4651	solute:proton antiporter activity
ACX61_16470	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACX61_16490	COG0724	RNA recognition motif
ACX61_16495	COG0210	DNA helicase
ACX61_16520	COG1733	regulation of RNA biosynthetic process
ACX61_16540	COG1280	lysine exporter protein (LysE YggA)
ACX61_16545	COG1560	Kdo2-lipid A biosynthetic process
ACX61_16555	COG1301	dicarboxylic acid transport
ACX61_16610	COG0473	3-isopropylmalate dehydrogenase activity
ACX61_16675	COG0583	DNA-binding transcription factor activity
ACX61_16685	COG0625	glutathione transferase activity
ACX61_16690	COG2378	regulation of single-species biofilm formation
ACX61_16695	COG0546	phosphoglycolate phosphatase activity
ACX61_16705	COG1530	ribonuclease E activity
ACX61_16725	COG0583	DNA-binding transcription factor activity
ACX61_16730	COG4221	oxidoreductase activity
ACX61_16735	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACX61_16745	COG0534	Mate efflux family protein
ACX61_16760	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACX61_16795	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ACX61_16800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACX61_16815	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ACX61_16825	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ACX61_16825	COG0644	oxidoreductase
ACX61_16835	COG0425	Belongs to the sulfur carrier protein TusA family
ACX61_16840	COG4535	Mg2 and Co2 transporter CorC
ACX61_16850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACX61_16870	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ACX61_16875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACX61_16875	COG0475	glutathione-regulated potassium exporter activity
ACX61_16890	COG0484	heat shock protein binding
ACX61_16895	COG0789	Transcriptional regulator
ACX61_16900	COG0598	Magnesium transport protein CorA
ACX61_16920	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ACX61_16925	COG1074	ATP-dependent DNA helicase activity
ACX61_16930	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ACX61_16950	COG2226	methyltransferase
ACX61_16965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACX61_16970	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ACX61_16985	COG2111	Na H antiporter
ACX61_16985	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACX61_16990	COG1006	Multisubunit Na H antiporter MnhC subunit
ACX61_16995	COG0651	ATP synthesis coupled electron transport
ACX61_17005	COG2212	antiporter activity
ACX61_17025	COG0195	Participates in both transcription termination and antitermination
ACX61_17075	COG0237	dephospho-CoA kinase activity
ACX61_17085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACX61_17100	COG0497	DNA recombination
ACX61_17110	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ACX61_17140	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACX61_17140	COG2169	Transcriptional regulator
ACX61_17145	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ACX61_17205	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ACX61_17220	COG0326	Molecular chaperone. Has ATPase activity
ACX61_17235	COG2056	Na+-H+ antiporter family
ACX61_17240	COG0596	Alpha beta hydrolase
ACX61_17255	COG3328	transposase activity
ACX61_17340	COG0546	phosphoglycolate phosphatase activity
ACX61_17345	COG1716	ATPase activity
ACX61_17390	COG0181	hydroxymethylbilane synthase activity
ACX61_17400	COG3275	phosphorelay sensor kinase activity
ACX61_17420	COG1538	Outer membrane efflux protein
ACX61_17425	COG0697	spore germination
ACX61_17450	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ACX61_17455	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ACX61_17460	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACX61_17465	COG0772	Belongs to the SEDS family
ACX61_17490	COG4974	Belongs to the 'phage' integrase family
ACX61_17495	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACX61_17505	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ACX61_17515	COG2197	response regulator
ACX61_17530	COG0793	Belongs to the peptidase S41A family
ACX61_17535	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ACX61_17540	COG0795	lipopolysaccharide-transporting ATPase activity
ACX61_17580	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACX61_17580	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACX61_17590	COG0004	ammonium transporteR
ACX61_17595	COG0347	Belongs to the P(II) protein family
ACX61_17635	COG1061	Type III restriction enzyme res subunit
ACX61_17655	COG0659	secondary active sulfate transmembrane transporter activity
ACX61_17660	COG0589	response to stress
ACX61_17705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACX61_17710	COG0235	Class ii aldolase
ACX61_17715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACX61_17730	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ACX61_17745	COG0318	PFAM AMP-dependent synthetase and ligase
ACX61_17755	COG0477	Major facilitator Superfamily
ACX61_17760	COG2860	membrane
ACX61_17765	COG3012	SEC-C Motif Domain Protein
ACX61_17770	COG1253	flavin adenine dinucleotide binding
ACX61_17780	COG2814	Major facilitator Superfamily
ACX61_17790	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACX61_17825	COG0655	NAD(P)H dehydrogenase (quinone) activity
ACX61_17835	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACX61_17870	COG1309	transcriptional regulator
ACX61_17905	COG0758	DNA mediated transformation
ACX61_17915	COG0697	spore germination
ACX61_17920	COG1309	transcriptional regulator
ACX61_17935	COG0386	Belongs to the glutathione peroxidase family
ACX61_18005	COG1121	(ABC) transporter
ACX61_18010	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACX61_18015	COG1280	lysine exporter protein (LysE YggA)
ACX61_18020	COG2837	iron assimilation
ACX61_18030	COG0281	malic enzyme
ACX61_18075	COG0519	Catalyzes the synthesis of GMP from XMP
ACX61_18075	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACX61_18080	COG4399	Belongs to the UPF0754 family
ACX61_18085	COG2259	Doxx family
ACX61_18090	COG0586	Pfam SNARE associated Golgi protein
ACX61_18105	COG1192	Involved in chromosome partitioning
ACX61_18115	COG0271	Belongs to the BolA IbaG family
ACX61_18135	COG1024	Enoyl-CoA hydratase
ACX61_18140	COG1024	Enoyl-CoA hydratase
ACX61_18145	COG1960	acyl-CoA dehydrogenase activity
ACX61_18150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACX61_18170	COG1113	amino acid transport
ACX61_18175	COG1113	amino acid transport
ACX61_18180	COG0251	oxidation-reduction process
ACX61_18195	COG1522	sequence-specific DNA binding
ACX61_18220	COG0564	pseudouridine synthase activity
ACX61_18290	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ACX61_18305	COG1802	Transcriptional regulator
ACX61_18310	COG1448	Aminotransferase
ACX61_18315	COG0277	FAD linked oxidase domain protein
ACX61_18325	COG2186	Transcriptional regulator
ACX61_18335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACX61_18340	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ACX61_18355	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ACX61_18360	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ACX61_18365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACX61_18410	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_18415	COG1083	cytidylyl-transferase
ACX61_18420	COG0673	inositol 2-dehydrogenase activity
ACX61_18425	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ACX61_18430	COG1045	serine acetyltransferase
ACX61_18435	COG2089	acid synthase
ACX61_18440	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ACX61_18445	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACX61_18455	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ACX61_18460	COG1596	polysaccharide export
ACX61_18485	COG0728	peptidoglycan biosynthetic process
ACX61_18490	COG3023	N-Acetylmuramoyl-L-alanine amidase
ACX61_18545	COG0546	phosphoglycolate phosphatase activity
ACX61_18550	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_18570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ACX61_18575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ACX61_18580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACX61_18590	COG1116	anion transmembrane transporter activity
ACX61_18595	COG1309	transcriptional regulator
ACX61_18600	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ACX61_18610	COG0196	riboflavin kinase activity
ACX61_18615	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ACX61_18625	COG1047	Peptidyl-prolyl cis-trans
ACX61_18665	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACX61_18690	COG0583	DNA-binding transcription factor activity
ACX61_18720	COG2951	lytic endotransglycosylase activity
ACX61_18725	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ACX61_18745	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACX61_18755	COG3328	transposase activity
ACX61_18765	COG0671	phosphoesterase, PA-phosphatase related
ACX61_18770	COG0861	Integral membrane protein TerC family
ACX61_18780	COG0754	glutathionylspermidine amidase activity
ACX61_18790	COG0402	S-adenosylhomocysteine deaminase activity
ACX61_18810	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACX61_18815	COG1230	cation diffusion facilitator family transporter
ACX61_18830	COG0706	membrane insertase activity
ACX61_18845	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ACX61_18915	COG0739	heme binding
ACX61_18955	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACX61_18965	COG1192	Involved in chromosome partitioning
ACX61_19015	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACX61_19150	COG3316	Transposase and inactivated derivatives
ACX61_19225	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ACX61_19270	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ACX61_19275	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ACX61_19290	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACX61_19305	COG1192	Involved in chromosome partitioning
ACX61_19365	COG3316	Transposase and inactivated derivatives
ACX61_19465	COG3173	Aminoglycoside phosphotransferase
ACX61_19480	COG3316	Transposase and inactivated derivatives
ACX61_19520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACX61_19570	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ACX61_19605	COG0501	Belongs to the peptidase M48B family
ACX61_19785	COG1525	nuclease
ACX61_19955	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACX61_19990	COG0741	lytic transglycosylase activity
ACX61_20065	COG1061	Type III restriction enzyme res subunit
ACX61_20085	COG0659	secondary active sulfate transmembrane transporter activity
ACX61_20090	COG0589	response to stress
ACX61_20170	COG0484	heat shock protein binding
ACX61_20220	COG2826	transposase and inactivated derivatives, IS30 family
ACX61_20240	COG2826	transposase and inactivated derivatives, IS30 family
ACX61_20265	COG3853	Toxic anion resistance protein (TelA)
ACX61_20285	COG1475	DNA binding