locus-tag	class	description
CTZ19_00010	COG0592	DNA-directed DNA polymerase activity
CTZ19_00020	COG0187	DNA topoisomerase II activity
CTZ19_00030	COG0586	Pfam SNARE associated Golgi protein
CTZ19_00035	COG0488	(ABC) transporter
CTZ19_00060	COG0596	Alpha beta hydrolase
CTZ19_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CTZ19_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CTZ19_00165	COG2233	PERMEase
CTZ19_00180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ19_00215	COG2814	Major facilitator Superfamily
CTZ19_00220	COG0656	L-ascorbic acid biosynthetic process
CTZ19_00225	COG0583	DNA-binding transcription factor activity
CTZ19_00240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ19_00245	COG1064	alcohol dehydrogenase
CTZ19_00250	COG2818	Glycosylase
CTZ19_00265	COG1194	a g-specific adenine glycosylase
CTZ19_00285	COG2983	Belongs to the UPF0260 family
CTZ19_00290	COG2133	pyrroloquinoline quinone binding
CTZ19_00295	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CTZ19_00300	COG2116	formate transmembrane transporter activity
CTZ19_00320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTZ19_00325	COG1335	isochorismatase
CTZ19_00330	COG0385	Bile acid
CTZ19_00335	COG0534	Mate efflux family protein
CTZ19_00340	COG1683	Conserved Protein
CTZ19_00360	COG0625	glutathione transferase activity
CTZ19_00370	COG1113	amino acid transport
CTZ19_00380	COG0523	cobalamin synthesis protein
CTZ19_00390	COG2188	Transcriptional regulator
CTZ19_00420	COG0010	Belongs to the arginase family
CTZ19_00435	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CTZ19_00440	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CTZ19_00450	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CTZ19_00455	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CTZ19_00560	COG0534	Mate efflux family protein
CTZ19_00565	COG0436	Aminotransferase
CTZ19_00570	COG2733	membrane
CTZ19_00585	COG2918	glutathione biosynthetic process
CTZ19_00595	COG3501	Rhs element vgr protein
CTZ19_00600	COG1388	LysM domain
CTZ19_00600	COG0791	NLP P60 protein
CTZ19_00615	COG3150	esterase
CTZ19_00625	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_00630	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CTZ19_00640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ19_00650	COG2233	PERMEase
CTZ19_00655	COG2351	hydroxyisourate hydrolase activity
CTZ19_00690	COG3706	GGDEF domain
CTZ19_00705	COG1393	Belongs to the ArsC family
CTZ19_00710	COG0708	Exodeoxyribonuclease III
CTZ19_00730	COG0189	ligase activity
CTZ19_00750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CTZ19_00760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CTZ19_00775	COG4942	peptidase
CTZ19_00785	COG0508	dehydrogenase complex catalyzes the overall conversion of
CTZ19_00795	COG2119	membrane
CTZ19_00800	COG4774	siderophore transport
CTZ19_00805	COG0426	domain, Protein
CTZ19_00805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ19_00830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CTZ19_00850	COG1902	pentaerythritol trinitrate reductase activity
CTZ19_00855	COG1519	Transferase
CTZ19_00860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CTZ19_00865	COG0668	transmembrane transport
CTZ19_00880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTZ19_00885	COG1335	isochorismatase
CTZ19_00890	COG1522	sequence-specific DNA binding
CTZ19_00895	COG3328	transposase activity
CTZ19_00920	COG2205	protein histidine kinase activity
CTZ19_00920	COG2198	Histidine kinase
CTZ19_00920	COG0784	Response regulator, receiver
CTZ19_00925	COG3162	membrane
CTZ19_00930	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CTZ19_00940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTZ19_00950	COG3706	GGDEF domain
CTZ19_00960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CTZ19_00965	COG1309	transcriptional regulator
CTZ19_00985	COG0352	thiamine-phosphate diphosphorylase activity
CTZ19_00985	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CTZ19_00985	COG0351	phosphomethylpyrimidine kinase
CTZ19_00995	COG2814	Major facilitator Superfamily
CTZ19_01010	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CTZ19_01020	COG1113	amino acid transport
CTZ19_01030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CTZ19_01035	COG1012	belongs to the aldehyde dehydrogenase family
CTZ19_01045	COG1335	isochorismatase
CTZ19_01075	COG2814	Major facilitator Superfamily
CTZ19_01080	COG0583	DNA-binding transcription factor activity
CTZ19_01100	COG0667	Aldo Keto reductase
CTZ19_01135	COG1733	regulation of RNA biosynthetic process
CTZ19_01145	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTZ19_01210	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CTZ19_01225	COG2329	Antibiotic biosynthesis monooxygenase
CTZ19_01255	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CTZ19_01285	COG0427	acetyl-CoA hydrolase
CTZ19_01300	COG0745	RESPONSE REGULATOR receiver
CTZ19_01310	COG0659	secondary active sulfate transmembrane transporter activity
CTZ19_01315	COG4221	oxidoreductase activity
CTZ19_01325	COG0488	(ABC) transporter
CTZ19_01410	COG0833	amino acid
CTZ19_01455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CTZ19_01460	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CTZ19_01475	COG2226	methyltransferase
CTZ19_01525	COG0069	glutamate synthase activity
CTZ19_01525	COG0070	glutamate synthase
CTZ19_01525	COG0067	glutamate synthase
CTZ19_01530	COG0493	'glutamate synthase
CTZ19_01540	COG1704	LemA family
CTZ19_01545	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CTZ19_01565	COG3307	-O-antigen
CTZ19_01585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CTZ19_01595	COG0194	GDP metabolic process
CTZ19_01645	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CTZ19_01665	COG5380	lipid catabolic process
CTZ19_01670	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CTZ19_01695	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CTZ19_01700	COG0277	FAD linked oxidase domain protein
CTZ19_01710	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CTZ19_01715	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTZ19_01730	COG1289	transmembrane transporter activity
CTZ19_01740	COG0628	permease
CTZ19_01745	COG1192	Involved in chromosome partitioning
CTZ19_01775	COG0833	amino acid
CTZ19_01780	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CTZ19_01785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CTZ19_01795	COG1012	belongs to the aldehyde dehydrogenase family
CTZ19_01835	COG0583	DNA-binding transcription factor activity
CTZ19_01880	COG0517	IMP dehydrogenase activity
CTZ19_01885	COG1983	PspC domain protein
CTZ19_01895	COG1960	acyl-CoA dehydrogenase activity
CTZ19_01910	COG0408	coproporphyrinogen oxidase activity
CTZ19_01930	COG0513	Belongs to the DEAD box helicase family
CTZ19_01935	COG1127	ABC transporter
CTZ19_01940	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CTZ19_01950	COG2854	intermembrane phospholipid transfer
CTZ19_01960	COG0598	Magnesium transport protein CorA
CTZ19_01970	COG0494	nUDIX hydrolase
CTZ19_01975	COG1040	competence protein
CTZ19_01980	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CTZ19_02000	COG1946	Acyl-CoA thioesterase
CTZ19_02005	COG1301	dicarboxylic acid transport
CTZ19_02020	COG1959	2 iron, 2 sulfur cluster binding
CTZ19_02025	COG1017	nitric oxide dioxygenase activity
CTZ19_02025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTZ19_02030	COG0433	COG0433 Predicted ATPase
CTZ19_02035	COG0626	cystathionine gamma-synthase activity
CTZ19_02155	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CTZ19_02165	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CTZ19_02190	COG1960	acyl-CoA dehydrogenase activity
CTZ19_02195	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CTZ19_02225	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CTZ19_02230	COG0339	signal peptide processing
CTZ19_02235	COG0557	exoribonuclease II activity
CTZ19_02280	COG0179	Fumarylacetoacetate (FAA) hydrolase
CTZ19_02285	COG2169	Transcriptional regulator
CTZ19_02290	COG0697	spore germination
CTZ19_02295	COG1295	ribonuclease BN
CTZ19_02330	COG1702	phosphate starvation-inducible protein PhoH
CTZ19_02340	COG0741	lytic transglycosylase activity
CTZ19_02340	COG1196	nuclear chromosome segregation
CTZ19_02340	COG0739	heme binding
CTZ19_02370	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CTZ19_02375	COG1183	phosphatidylcholine synthase activity
CTZ19_02420	COG1960	acyl-CoA dehydrogenase activity
CTZ19_02425	COG1309	transcriptional regulator
CTZ19_02440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CTZ19_02445	COG1960	acyl-CoA dehydrogenase activity
CTZ19_02465	COG2969	positive regulation of protein catabolic process
CTZ19_02475	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CTZ19_02490	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CTZ19_02495	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CTZ19_02515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CTZ19_02525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CTZ19_02530	COG1408	metallophosphoesterase
CTZ19_02540	COG2199	diguanylate cyclase activity
CTZ19_02585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTZ19_02585	COG3453	Protein conserved in bacteria
CTZ19_02600	COG1607	acyl-coa hydrolase
CTZ19_02630	COG2350	Protein conserved in bacteria
CTZ19_02640	COG0613	PHP domain protein
CTZ19_02645	COG3781	membrane
CTZ19_02655	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CTZ19_02660	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CTZ19_02670	COG1862	Preprotein translocase
CTZ19_02720	COG0629	single-stranded DNA binding
CTZ19_02790	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CTZ19_02930	COG4695	Portal protein
CTZ19_02940	COG2205	protein histidine kinase activity
CTZ19_02945	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CTZ19_02965	COG0726	polysaccharide deacetylase
CTZ19_02970	COG0463	Glycosyl transferase, family 2
CTZ19_02975	COG0438	transferase activity, transferring glycosyl groups
CTZ19_03040	COG0625	glutathione transferase activity
CTZ19_03045	COG0583	DNA-binding transcription factor activity
CTZ19_03050	COG1960	acyl-CoA dehydrogenase activity
CTZ19_03055	COG1960	acyl-CoA dehydrogenase activity
CTZ19_03065	COG2205	protein histidine kinase activity
CTZ19_03070	COG0745	RESPONSE REGULATOR receiver
CTZ19_03075	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CTZ19_03095	COG2096	Adenosyltransferase
CTZ19_03110	COG0133	tryptophan synthase activity
CTZ19_03145	COG0285	dihydrofolate synthase activity
CTZ19_03165	COG0450	alkyl hydroperoxide reductase
CTZ19_03180	COG0477	Major facilitator Superfamily
CTZ19_03185	COG1272	protein, Hemolysin III
CTZ19_03215	COG0183	Belongs to the thiolase family
CTZ19_03220	COG2207	Transcriptional regulator
CTZ19_03240	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ19_03260	COG0183	Belongs to the thiolase family
CTZ19_03270	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CTZ19_03270	COG2885	chlorophyll binding
CTZ19_03280	COG1690	Belongs to the RtcB family
CTZ19_03285	COG0833	amino acid
CTZ19_03295	COG2233	PERMEase
CTZ19_03325	COG2094	Belongs to the DNA glycosylase MPG family
CTZ19_03330	COG4772	TonB-dependent receptor
CTZ19_03345	COG1902	pentaerythritol trinitrate reductase activity
CTZ19_03350	COG0679	Auxin Efflux Carrier
CTZ19_03360	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CTZ19_03365	COG0354	folic acid binding
CTZ19_03375	COG3189	MarR family transcriptional regulator
CTZ19_03380	COG2824	Alkylphosphonate utilization operon protein PhnA
CTZ19_03385	COG3422	double-strand break repair
CTZ19_03425	COG0840	transmembrane signaling receptor activity
CTZ19_03445	COG5510	response to toxic substance
CTZ19_03455	COG2832	Protein of unknown function (DUF454)
CTZ19_03460	COG1376	ErfK ybiS ycfS ynhG family protein
CTZ19_03510	COG1289	transmembrane transporter activity
CTZ19_03515	COG2814	Major facilitator Superfamily
CTZ19_03535	COG1115	amino acid carrier protein
CTZ19_03540	COG1752	Esterase of the alpha-beta hydrolase superfamily
CTZ19_03545	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CTZ19_03550	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CTZ19_03580	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CTZ19_03590	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CTZ19_03595	COG1077	Cell shape determining protein MreB Mrl
CTZ19_03600	COG1792	Involved in formation and maintenance of cell shape
CTZ19_03605	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CTZ19_03610	COG0424	maF-like protein
CTZ19_03615	COG1530	ribonuclease E activity
CTZ19_03625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ19_03645	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTZ19_03670	COG2207	Transcriptional regulator
CTZ19_03690	COG1113	amino acid transport
CTZ19_03695	COG2828	Protein conserved in bacteria
CTZ19_03700	COG0142	geranyltranstransferase activity
CTZ19_03705	COG2315	Protein conserved in bacteria
CTZ19_03720	COG1752	Esterase of the alpha-beta hydrolase superfamily
CTZ19_03740	COG2194	sulfuric ester hydrolase activity
CTZ19_03745	COG0745	RESPONSE REGULATOR receiver
CTZ19_03750	COG0642	Histidine kinase
CTZ19_03760	COG0004	ammonium transporteR
CTZ19_03770	COG0583	DNA-binding transcription factor activity
CTZ19_03790	COG0525	valine-tRNA ligase activity
CTZ19_03800	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_03810	COG0393	Putative heavy-metal-binding
CTZ19_03815	COG0393	Putative heavy-metal-binding
CTZ19_03820	COG1538	Outer membrane efflux protein
CTZ19_03830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ19_03835	COG0671	phosphoesterase, PA-phosphatase related
CTZ19_03865	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CTZ19_03880	COG1648	precorrin-2 dehydrogenase activity
CTZ19_03880	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CTZ19_03885	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CTZ19_03890	COG1733	regulation of RNA biosynthetic process
CTZ19_03900	COG0531	amino acid
CTZ19_03915	COG0321	lipoyl(octanoyl) transferase activity
CTZ19_03920	COG2921	Belongs to the UPF0250 family
CTZ19_03960	COG2009	succinate dehydrogenase
CTZ19_03965	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CTZ19_03970	COG1053	succinate dehydrogenase
CTZ19_03975	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CTZ19_04000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTZ19_04020	COG2354	Protein conserved in bacteria
CTZ19_04025	COG2321	neutral zinc metallopeptidase
CTZ19_04055	COG2843	Capsule synthesis protein
CTZ19_04070	COG0589	response to stress
CTZ19_04090	COG0505	Belongs to the CarA family
CTZ19_04120	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CTZ19_04125	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CTZ19_04175	COG0477	Major facilitator Superfamily
CTZ19_04180	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CTZ19_04200	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CTZ19_04230	COG0584	glycerophosphoryl diester phosphodiesterase
CTZ19_04250	COG0741	lytic transglycosylase activity
CTZ19_04275	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CTZ19_04290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ19_04315	COG0778	Nitroreductase
CTZ19_04330	COG1929	Belongs to the glycerate kinase type-1 family
CTZ19_04335	COG0243	molybdopterin cofactor binding
CTZ19_04340	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CTZ19_04345	COG3339	Conserved Protein
CTZ19_04355	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CTZ19_04370	COG1113	amino acid transport
CTZ19_04380	COG0019	diaminopimelate decarboxylase activity
CTZ19_04390	COG1280	lysine exporter protein (LysE YggA)
CTZ19_04395	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CTZ19_04425	COG0463	Glycosyl transferase, family 2
CTZ19_04445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ19_04475	COG4591	ABC-type transport system involved in lipoprotein release permease component
CTZ19_04480	COG1136	(ABC) transporter
CTZ19_04485	COG2333	competence protein COMEC
CTZ19_04485	COG0658	competence protein
CTZ19_04495	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CTZ19_04495	COG0616	signal peptide processing
CTZ19_04500	COG0596	Alpha beta hydrolase
CTZ19_04505	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CTZ19_04515	COG0628	permease
CTZ19_04550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTZ19_04570	COG0823	Involved in the tonB-independent uptake of proteins
CTZ19_04590	COG0824	Thioesterase
CTZ19_04595	COG1473	amidohydrolase
CTZ19_04615	COG0047	phosphoribosylformylglycinamidine synthase activity
CTZ19_04615	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CTZ19_04620	COG2814	Major facilitator Superfamily
CTZ19_04625	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CTZ19_04630	COG1024	Enoyl-CoA hydratase
CTZ19_04635	COG1051	belongs to the nudix hydrolase family
CTZ19_04635	COG1056	cytidyltransferase-related domain
CTZ19_04645	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CTZ19_04660	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CTZ19_04675	COG4625	pathogenesis
CTZ19_04680	COG0583	DNA-binding transcription factor activity
CTZ19_04685	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CTZ19_04690	COG4208	sulfate ABC transporter
CTZ19_04695	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CTZ19_04705	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CTZ19_04710	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CTZ19_04715	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CTZ19_04735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTZ19_04750	COG0681	Belongs to the peptidase S26 family
CTZ19_04765	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CTZ19_04775	COG1381	Involved in DNA repair and RecF pathway recombination
CTZ19_04780	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CTZ19_04790	COG4221	oxidoreductase activity
CTZ19_04840	COG0556	nucleotide-excision repair
CTZ19_05035	COG5410	chromosome segregation
CTZ19_05225	COG2070	2-Nitropropane dioxygenase
CTZ19_05255	COG1215	transferase activity, transferring glycosyl groups
CTZ19_05270	COG0415	Belongs to the DNA photolyase family
CTZ19_05280	COG1252	NADH dehydrogenase
CTZ19_05285	COG1686	Belongs to the peptidase S11 family
CTZ19_05300	COG1187	pseudouridine synthase activity
CTZ19_05325	COG0477	Major facilitator Superfamily
CTZ19_05330	COG0583	DNA-binding transcription factor activity
CTZ19_05345	COG0612	Peptidase, M16
CTZ19_05370	COG0352	thiamine-phosphate diphosphorylase activity
CTZ19_05405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTZ19_05420	COG1309	transcriptional regulator
CTZ19_05430	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CTZ19_05435	COG0076	glutamate decarboxylase activity
CTZ19_05445	COG1522	sequence-specific DNA binding
CTZ19_05450	COG3961	Belongs to the TPP enzyme family
CTZ19_05455	COG1113	amino acid transport
CTZ19_05460	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CTZ19_05465	COG0573	inorganic phosphate transmembrane transporter activity
CTZ19_05475	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CTZ19_05480	COG0616	signal peptide processing
CTZ19_05515	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CTZ19_05520	COG1686	Belongs to the peptidase S11 family
CTZ19_05545	COG0583	DNA-binding transcription factor activity
CTZ19_05550	COG1067	ATP-dependent peptidase activity
CTZ19_05595	COG1966	Carbon starvation protein
CTZ19_05600	COG2879	small protein
CTZ19_05635	COG2508	Transcriptional regulator
CTZ19_05635	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CTZ19_05655	COG1113	amino acid transport
CTZ19_05660	COG0583	DNA-binding transcription factor activity
CTZ19_05665	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTZ19_05670	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTZ19_05685	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ19_05690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTZ19_05690	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CTZ19_05725	COG2814	Major facilitator Superfamily
CTZ19_05730	COG4948	Mandelate Racemase Muconate Lactonizing
CTZ19_05740	COG1309	transcriptional regulator
CTZ19_05760	COG1741	Belongs to the pirin family
CTZ19_05770	COG2964	Protein conserved in bacteria
CTZ19_05785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ19_05790	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTZ19_05795	COG4605	iron ion homeostasis
CTZ19_05800	COG4604	ABC transporter, ATP-binding protein
CTZ19_05805	COG4607	ABC-type enterochelin transport system periplasmic component
CTZ19_05810	COG4774	siderophore transport
CTZ19_05820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ19_05825	COG1021	2,3-dihydroxybenzoate-AMP ligase
CTZ19_05830	COG3433	isochorismatase activity
CTZ19_05830	COG1535	isochorismatase
CTZ19_05845	COG1132	(ABC) transporter
CTZ19_05855	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CTZ19_05865	COG1169	isochorismate synthase
CTZ19_05880	COG3739	integral membrane protein
CTZ19_05915	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CTZ19_05945	COG0308	aminopeptidase N
CTZ19_05950	COG0512	Glutamine amidotransferase of anthranilate synthase
CTZ19_05960	COG3104	oligopeptide transport
CTZ19_05975	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CTZ19_06010	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CTZ19_06015	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CTZ19_06020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTZ19_06040	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CTZ19_06045	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CTZ19_06050	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CTZ19_06065	COG1960	acyl-CoA dehydrogenase activity
CTZ19_06070	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CTZ19_06075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTZ19_06085	COG2223	nitrite transmembrane transporter activity
CTZ19_06095	COG0024	Methionine aminopeptidase
CTZ19_06100	COG0052	Belongs to the universal ribosomal protein uS2 family
CTZ19_06115	COG2207	Transcriptional regulator
CTZ19_06140	COG2951	lytic endotransglycosylase activity
CTZ19_06145	COG0772	Belongs to the SEDS family
CTZ19_06160	COG0842	Transport permease protein
CTZ19_06165	COG1131	(ABC) transporter
CTZ19_06200	COG1538	Outer membrane efflux protein
CTZ19_06210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ19_06225	COG4215	(ABC) transporter
CTZ19_06230	COG4160	amino acid transport
CTZ19_06235	COG4598	ABC transporter
CTZ19_06245	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTZ19_06255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ19_06270	COG1720	tRNA m6t6A37 methyltransferase activity
CTZ19_06290	COG0745	RESPONSE REGULATOR receiver
CTZ19_06295	COG0642	Histidine kinase
CTZ19_06305	COG0494	nUDIX hydrolase
CTZ19_06315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CTZ19_06320	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CTZ19_06325	COG3139	Protein of unknown function (DUF1315)
CTZ19_06330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CTZ19_06340	COG1301	dicarboxylic acid transport
CTZ19_06345	COG1960	acyl-CoA dehydrogenase activity
CTZ19_06350	COG2819	hydrolase of the alpha beta superfamily
CTZ19_06360	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CTZ19_06370	COG2195	Cleaves the N-terminal amino acid of tripeptides
CTZ19_06375	COG1234	tRNA 3'-trailer cleavage
CTZ19_06405	COG2363	Small membrane protein
CTZ19_06425	COG0513	Belongs to the DEAD box helicase family
CTZ19_06435	COG0778	Nitroreductase
CTZ19_06465	COG1286	toxin biosynthetic process
CTZ19_06490	COG4783	chaperone-mediated protein folding
CTZ19_06495	COG1610	YqeY-like protein
CTZ19_06500	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CTZ19_06595	COG3111	PFAM Bacterial OB fold (BOF) protein
CTZ19_06620	COG3243	poly(R)-hydroxyalkanoic acid synthase
CTZ19_06625	COG0786	glutamate:sodium symporter activity
CTZ19_06635	COG2186	Transcriptional regulator
CTZ19_06685	COG0477	Major facilitator Superfamily
CTZ19_06715	COG2985	domain, Protein
CTZ19_06725	COG2995	paraquat-inducible protein a
CTZ19_06735	COG3316	Transposase and inactivated derivatives
CTZ19_06750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTZ19_06755	COG2011	ABC-type metal ion transport system permease component
CTZ19_06760	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CTZ19_06765	COG1464	Belongs to the NlpA lipoprotein family
CTZ19_06770	COG0151	Belongs to the GarS family
CTZ19_06775	COG0138	bifunctional purine biosynthesis protein purh
CTZ19_06780	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CTZ19_06810	COG2308	Evidence 4 Homologs of previously reported genes of
CTZ19_06820	COG1305	Transglutaminase-like
CTZ19_06830	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CTZ19_06835	COG0305	Participates in initiation and elongation during chromosome replication
CTZ19_06860	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CTZ19_06870	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CTZ19_06875	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CTZ19_06900	COG1649	PFAM Uncharacterised BCR, COG1649
CTZ19_06900	COG0726	polysaccharide deacetylase
CTZ19_06905	COG1215	transferase activity, transferring glycosyl groups
CTZ19_06920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTZ19_06940	COG0583	DNA-binding transcription factor activity
CTZ19_06960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTZ19_06965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTZ19_06980	COG1960	acyl-CoA dehydrogenase activity
CTZ19_06985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTZ19_06990	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ19_07015	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CTZ19_07020	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CTZ19_07030	COG2205	protein histidine kinase activity
CTZ19_07035	COG0745	RESPONSE REGULATOR receiver
CTZ19_07040	COG0174	glutamine synthetase
CTZ19_07060	COG0729	surface antigen
CTZ19_07090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CTZ19_07095	COG2814	Major facilitator Superfamily
CTZ19_07110	COG0583	DNA-binding transcription factor activity
CTZ19_07125	COG1187	pseudouridine synthase activity
CTZ19_07145	COG0802	atpase or kinase
CTZ19_07150	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CTZ19_07160	COG1923	regulation of RNA biosynthetic process
CTZ19_07165	COG0697	spore germination
CTZ19_07180	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTZ19_07195	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CTZ19_07195	COG0519	Catalyzes the synthesis of GMP from XMP
CTZ19_07200	COG4302	ethanolamine ammonia-lyase activity
CTZ19_07205	COG4303	Ethanolamine ammonia lyase large subunit
CTZ19_07210	COG0531	amino acid
CTZ19_07230	COG1454	alcohol dehydrogenase
CTZ19_07235	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CTZ19_07245	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CTZ19_07265	COG0308	aminopeptidase N
CTZ19_07275	COG4221	oxidoreductase activity
CTZ19_07285	COG1605	Chorismate mutase
CTZ19_07305	COG1309	transcriptional regulator
CTZ19_07315	COG0668	transmembrane transport
CTZ19_07350	COG4773	Receptor
CTZ19_07370	COG0488	(ABC) transporter
CTZ19_07375	COG0589	response to stress
CTZ19_07395	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CTZ19_07405	COG3135	benzoate transporter
CTZ19_07410	COG1522	sequence-specific DNA binding
CTZ19_07425	COG0583	DNA-binding transcription factor activity
CTZ19_07435	COG0183	Belongs to the thiolase family
CTZ19_07465	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CTZ19_07475	COG0824	Thioesterase
CTZ19_07480	COG1454	alcohol dehydrogenase
CTZ19_07490	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CTZ19_07510	COG0069	glutamate synthase activity
CTZ19_07670	COG5410	chromosome segregation
CTZ19_07795	COG0739	heme binding
CTZ19_07865	COG2814	Major facilitator Superfamily
CTZ19_07880	COG0511	ligase activity, forming carbon-carbon bonds
CTZ19_07895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTZ19_07895	COG1116	anion transmembrane transporter activity
CTZ19_07900	COG0745	RESPONSE REGULATOR receiver
CTZ19_07910	COG2146	nitrite reductase [NAD(P)H] activity
CTZ19_07910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ19_07915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ19_07920	COG0243	molybdopterin cofactor binding
CTZ19_07930	COG0243	molybdopterin cofactor binding
CTZ19_07935	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CTZ19_07950	COG0315	cyclic pyranopterin monophosphate synthase activity
CTZ19_07950	COG0521	Mo-molybdopterin cofactor biosynthetic process
CTZ19_07955	COG0303	'Molybdopterin
CTZ19_07965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ19_07970	COG0697	spore germination
CTZ19_07990	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CTZ19_07995	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CTZ19_08055	COG2204	response regulator
CTZ19_08060	COG3852	Histidine kinase
CTZ19_08080	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CTZ19_08085	COG0575	Belongs to the CDS family
CTZ19_08120	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTZ19_08135	COG2137	regulation of response to DNA damage stimulus
CTZ19_08145	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CTZ19_08150	COG1011	Hydrolase
CTZ19_08175	COG1522	sequence-specific DNA binding
CTZ19_08185	COG1113	amino acid transport
CTZ19_08205	COG0659	secondary active sulfate transmembrane transporter activity
CTZ19_08210	COG2135	peptidase activity
CTZ19_08225	COG5001	Diguanylate cyclase
CTZ19_08225	COG3300	MHYT domain
CTZ19_08245	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTZ19_08245	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CTZ19_08245	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTZ19_08250	COG1105	Belongs to the carbohydrate kinase PfkB family
CTZ19_08255	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTZ19_08255	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CTZ19_08285	COG0024	Methionine aminopeptidase
CTZ19_08290	COG0583	DNA-binding transcription factor activity
CTZ19_08300	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CTZ19_08305	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CTZ19_08310	COG0516	GMP reductase activity
CTZ19_08310	COG0517	IMP dehydrogenase activity
CTZ19_08335	COG0552	protein localization to endoplasmic reticulum
CTZ19_08345	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CTZ19_08360	COG4890	Cyd operon protein YbgT
CTZ19_08365	COG1294	oxidase, subunit
CTZ19_08385	COG1585	Membrane protein implicated in regulation of membrane protease activity
CTZ19_08395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CTZ19_08400	COG4774	siderophore transport
CTZ19_08415	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CTZ19_08420	COG0569	domain protein
CTZ19_08425	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CTZ19_08455	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CTZ19_08460	COG0542	response to heat
CTZ19_08470	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CTZ19_08485	COG1902	pentaerythritol trinitrate reductase activity
CTZ19_08485	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTZ19_08530	COG2323	membrane
CTZ19_08535	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CTZ19_08545	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CTZ19_08550	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTZ19_08555	COG0183	Belongs to the thiolase family
CTZ19_08560	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CTZ19_08565	COG0596	Alpha beta hydrolase
CTZ19_08570	COG2271	Major facilitator Superfamily
CTZ19_08575	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTZ19_08580	COG3485	protocatechuate 3,4-dioxygenase
CTZ19_08585	COG3485	protocatechuate 3,4-dioxygenase
CTZ19_08590	COG0710	3-dehydroquinate dehydratase activity
CTZ19_08595	COG3420	alginic acid biosynthetic process
CTZ19_08600	COG3659	wide pore channel activity
CTZ19_08605	COG4993	Dehydrogenase
CTZ19_08615	COG2391	methyltransferase activity
CTZ19_08630	COG1414	Transcriptional regulator
CTZ19_08635	COG0583	DNA-binding transcription factor activity
CTZ19_08640	COG1960	acyl-CoA dehydrogenase activity
CTZ19_08665	COG2814	Major facilitator Superfamily
CTZ19_08675	COG0154	amidase activity
CTZ19_08695	COG4638	Rieske (2fe-2S)
CTZ19_08705	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_08715	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ19_08725	COG3733	amine oxidase
CTZ19_08735	COG1012	belongs to the aldehyde dehydrogenase family
CTZ19_08745	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTZ19_08750	COG0183	Belongs to the thiolase family
CTZ19_08755	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTZ19_08760	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CTZ19_08770	COG4829	muconolactone delta-isomerase
CTZ19_08775	COG4948	Mandelate Racemase Muconate Lactonizing
CTZ19_08780	COG0583	DNA-binding transcription factor activity
CTZ19_08790	COG2186	Transcriptional regulator
CTZ19_08810	COG1012	belongs to the aldehyde dehydrogenase family
CTZ19_08830	COG1960	acyl-CoA dehydrogenase activity
CTZ19_08835	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_08840	COG3829	transcription factor binding
CTZ19_08850	COG3162	membrane
CTZ19_08865	COG1012	belongs to the aldehyde dehydrogenase family
CTZ19_08880	COG0753	catalase activity
CTZ19_08905	COG1846	Transcriptional regulator
CTZ19_08910	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTZ19_08910	COG1902	pentaerythritol trinitrate reductase activity
CTZ19_08920	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CTZ19_08950	COG1309	transcriptional regulator
CTZ19_08960	COG1335	isochorismatase
CTZ19_08965	COG0583	DNA-binding transcription factor activity
CTZ19_08975	COG0475	glutathione-regulated potassium exporter activity
CTZ19_08975	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CTZ19_08985	COG1473	amidohydrolase
CTZ19_09000	COG2831	hemolysin activation secretion protein
CTZ19_09005	COG3210	domain, Protein
CTZ19_09050	COG0583	DNA-binding transcription factor activity
CTZ19_09075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CTZ19_09080	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CTZ19_09100	COG1566	PFAM secretion protein HlyD family protein
CTZ19_09115	COG1012	belongs to the aldehyde dehydrogenase family
CTZ19_09120	COG0129	dihydroxy-acid dehydratase activity
CTZ19_09130	COG0583	DNA-binding transcription factor activity
CTZ19_09135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CTZ19_09145	COG2084	Dehydrogenase
CTZ19_09150	COG2207	Transcriptional regulator
CTZ19_09165	COG1064	alcohol dehydrogenase
CTZ19_09180	COG1120	ATPase activity
CTZ19_09200	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CTZ19_09320	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CTZ19_09370	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_09385	COG2207	Transcriptional regulator
CTZ19_09395	COG2205	protein histidine kinase activity
CTZ19_09400	COG0745	RESPONSE REGULATOR receiver
CTZ19_09410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ19_09415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTZ19_09420	COG1538	Outer membrane efflux protein
CTZ19_09430	COG2072	flavoprotein involved in K transport
CTZ19_09450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTZ19_09470	COG3539	Fimbrial protein
CTZ19_09500	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CTZ19_09510	COG0753	catalase activity
CTZ19_09525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CTZ19_09590	COG3433	isochorismatase activity
CTZ19_09590	COG1535	isochorismatase
CTZ19_09595	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_09600	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CTZ19_09605	COG4149	molybdate abc transporter
CTZ19_09610	COG0725	ABC transporter, periplasmic molybdate-binding protein
CTZ19_09620	COG4638	Rieske (2fe-2S)
CTZ19_09625	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CTZ19_09630	COG0543	2 iron, 2 sulfur cluster binding
CTZ19_09630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTZ19_09645	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ19_09655	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_09660	COG0412	Dienelactone hydrolase
CTZ19_09670	COG2207	Transcriptional regulator
CTZ19_09680	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_09685	COG2610	gluconate transmembrane transporter activity
CTZ19_09695	COG0583	DNA-binding transcription factor activity
CTZ19_09705	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTZ19_09710	COG2031	fatty acid transporter
CTZ19_09715	COG0183	Belongs to the thiolase family
CTZ19_09720	COG0583	DNA-binding transcription factor activity
CTZ19_09725	COG0583	DNA-binding transcription factor activity
CTZ19_09740	COG1027	Aspartate ammonia-lyase
CTZ19_09750	COG0477	Major facilitator Superfamily
CTZ19_09770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTZ19_09775	COG4521	taurine ABC transporter
CTZ19_09800	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CTZ19_09805	COG1733	regulation of RNA biosynthetic process
CTZ19_09810	COG3708	Transcriptional regulator
CTZ19_09810	COG2207	Transcriptional regulator
CTZ19_09825	COG0730	response to heat
CTZ19_09835	COG3453	Protein conserved in bacteria
CTZ19_09835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTZ19_09845	COG3781	membrane
CTZ19_09850	COG1063	alcohol dehydrogenase
CTZ19_09860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTZ19_09865	COG0508	dehydrogenase complex catalyzes the overall conversion of
CTZ19_09870	COG0022	dehydrogenase e1 component
CTZ19_09875	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CTZ19_09880	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CTZ19_09895	COG3706	GGDEF domain
CTZ19_09910	COG0133	tryptophan synthase activity
CTZ19_09920	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CTZ19_09955	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CTZ19_09980	COG2226	methyltransferase
CTZ19_10035	COG0842	Transport permease protein
CTZ19_10040	COG0842	Transport permease protein
CTZ19_10045	COG1131	(ABC) transporter
CTZ19_10060	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTZ19_10065	COG4773	Receptor
CTZ19_10085	COG0730	response to heat
CTZ19_10090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CTZ19_10110	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CTZ19_10165	COG4264	IucA IucC family
CTZ19_10170	COG4264	IucA IucC family
CTZ19_10190	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CTZ19_10205	COG1960	acyl-CoA dehydrogenase activity
CTZ19_10210	COG1960	acyl-CoA dehydrogenase activity
CTZ19_10215	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTZ19_10220	COG2207	Transcriptional regulator
CTZ19_10225	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CTZ19_10230	COG0776	regulation of translation
CTZ19_10255	COG0822	iron-sulfur transferase activity
CTZ19_10260	COG0316	Belongs to the HesB IscA family
CTZ19_10290	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CTZ19_10310	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CTZ19_10315	COG0702	epimerase
CTZ19_10350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTZ19_10360	COG0339	signal peptide processing
CTZ19_10405	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CTZ19_10410	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CTZ19_10440	COG0776	regulation of translation
CTZ19_10460	COG0590	tRNA wobble adenosine to inosine editing
CTZ19_10490	COG2165	general secretion pathway protein
CTZ19_10505	COG0084	hydrolase, TatD family'
CTZ19_10525	COG1663	tetraacyldisaccharide 4'-kinase activity
CTZ19_10530	COG1132	(ABC) transporter
CTZ19_10540	COG0811	peptide transport
CTZ19_10545	COG1475	DNA binding
CTZ19_10550	COG1192	Involved in chromosome partitioning
CTZ19_10560	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CTZ19_10575	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CTZ19_10580	COG0191	fructose-bisphosphate aldolase activity
CTZ19_10600	COG0424	maF-like protein
CTZ19_10605	COG2850	peptidyl-arginine hydroxylation
CTZ19_10615	COG0640	Transcriptional regulator
CTZ19_10625	COG3619	membrane
CTZ19_10630	COG3122	Protein conserved in bacteria
CTZ19_10635	COG1132	(ABC) transporter
CTZ19_10655	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CTZ19_10660	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CTZ19_10670	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CTZ19_10670	COG0506	proline dehydrogenase activity
CTZ19_10670	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CTZ19_10675	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CTZ19_10690	COG3698	Phosphodiester glycosidase
CTZ19_10700	COG2353	YceI-like domain
CTZ19_10710	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CTZ19_10755	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CTZ19_10755	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CTZ19_10780	COG3539	Fimbrial protein
CTZ19_10785	COG3121	Chaperone
CTZ19_10815	COG0697	spore germination
CTZ19_10825	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CTZ19_10835	COG0583	DNA-binding transcription factor activity
CTZ19_10855	COG1309	transcriptional regulator
CTZ19_10875	COG1522	sequence-specific DNA binding
CTZ19_10885	COG1126	abc transporter atp-binding protein
CTZ19_10890	COG0765	amino acid transport
CTZ19_10895	COG0765	amino acid transport
CTZ19_10925	COG1464	Belongs to the NlpA lipoprotein family
CTZ19_10935	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CTZ19_10940	COG2011	ABC-type metal ion transport system permease component
CTZ19_10945	COG0012	GTP binding
CTZ19_10970	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CTZ19_11010	COG0386	Belongs to the glutathione peroxidase family
CTZ19_11020	COG0436	Aminotransferase
CTZ19_11060	COG3634	alkyl hydroperoxide reductase activity
CTZ19_11075	COG0583	DNA-binding transcription factor activity
CTZ19_11080	COG0798	PFAM Bile acid sodium symporter
CTZ19_11085	COG0640	Transcriptional regulator
CTZ19_11100	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CTZ19_11110	COG0583	DNA-binding transcription factor activity
CTZ19_11120	COG1953	Uracil, thiamine, allantoin
CTZ19_11130	COG2175	clavaminate synthase activity
CTZ19_11135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTZ19_11140	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CTZ19_11145	COG4521	taurine ABC transporter
CTZ19_11155	COG0477	Major facilitator Superfamily
CTZ19_11180	COG1271	oxidase subunit
CTZ19_11185	COG1294	oxidase, subunit
CTZ19_11195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ19_11215	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CTZ19_11235	COG3052	prosthetic group binding
CTZ19_11240	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CTZ19_11250	COG2814	Major facilitator Superfamily
CTZ19_11270	COG1346	cytolysis
CTZ19_11280	COG0583	DNA-binding transcription factor activity
CTZ19_11285	COG0625	glutathione transferase activity
CTZ19_11290	COG0625	glutathione transferase activity
CTZ19_11295	COG0583	DNA-binding transcription factor activity
CTZ19_11310	COG1045	serine acetyltransferase
CTZ19_11315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CTZ19_11320	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CTZ19_11325	COG1280	lysine exporter protein (LysE YggA)
CTZ19_11340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTZ19_11345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTZ19_11350	COG1126	abc transporter atp-binding protein
CTZ19_11355	COG0765	amino acid transport
CTZ19_11360	COG0765	amino acid transport
CTZ19_11380	COG2205	protein histidine kinase activity
CTZ19_11380	COG0784	Response regulator, receiver
CTZ19_11400	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CTZ19_11420	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_11465	COG0583	DNA-binding transcription factor activity
CTZ19_11485	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ19_11490	COG1309	transcriptional regulator
CTZ19_11495	COG1960	acyl-CoA dehydrogenase activity
CTZ19_11500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CTZ19_11505	COG1024	Enoyl-CoA hydratase
CTZ19_11520	COG0583	DNA-binding transcription factor activity
CTZ19_11535	COG1960	acyl-CoA dehydrogenase activity
CTZ19_11545	COG2814	Major facilitator Superfamily
CTZ19_11555	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTZ19_11560	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CTZ19_11565	COG2814	Major facilitator Superfamily
CTZ19_11570	COG1960	acyl-CoA dehydrogenase activity
CTZ19_11575	COG1024	Enoyl-CoA hydratase
CTZ19_11580	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_11590	COG0183	Belongs to the thiolase family
CTZ19_11600	COG2814	Major facilitator Superfamily
CTZ19_11610	COG1024	Enoyl-CoA hydratase
CTZ19_11625	COG1960	acyl-CoA dehydrogenase activity
CTZ19_11630	COG2814	Major facilitator Superfamily
CTZ19_11635	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CTZ19_11640	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CTZ19_11655	COG3842	ATPase activity
CTZ19_11660	COG1840	ABC-type Fe3 transport system, periplasmic component
CTZ19_11670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ19_11675	COG1414	Transcriptional regulator
CTZ19_11685	COG0583	DNA-binding transcription factor activity
CTZ19_11690	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTZ19_11695	COG1012	belongs to the aldehyde dehydrogenase family
CTZ19_11705	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CTZ19_11715	COG1012	belongs to the aldehyde dehydrogenase family
CTZ19_11720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTZ19_11725	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ19_11730	COG2267	carboxylic ester hydrolase activity
CTZ19_11750	COG3038	cytochrome b561
CTZ19_11755	COG0753	catalase activity
CTZ19_11795	COG2050	protein possibly involved in aromatic compounds catabolism
CTZ19_11805	COG3327	negative regulation of DNA-templated transcription, initiation
CTZ19_11810	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CTZ19_11815	COG0183	Belongs to the thiolase family
CTZ19_11820	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTZ19_11825	COG1024	Enoyl-CoA hydratase
CTZ19_11830	COG1024	Enoyl-CoA hydratase
CTZ19_11835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTZ19_11840	COG2151	metal-sulfur cluster biosynthetic enzyme
CTZ19_11845	COG3396	Phenylacetate-CoA oxygenase
CTZ19_11850	COG3460	Phenylacetate-CoA oxygenase
CTZ19_11855	COG3396	Phenylacetate-CoA oxygenase
CTZ19_11860	COG1012	belongs to the aldehyde dehydrogenase family
CTZ19_11860	COG2030	dehydratase
CTZ19_11865	COG1760	l-serine dehydratase
CTZ19_11870	COG0531	amino acid
CTZ19_11875	COG1012	belongs to the aldehyde dehydrogenase family
CTZ19_11890	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTZ19_11900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTZ19_11920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTZ19_11935	COG0789	Transcriptional regulator
CTZ19_11960	COG1116	anion transmembrane transporter activity
CTZ19_11965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTZ19_11975	COG0864	Transcriptional regulator
CTZ19_11995	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTZ19_12000	COG0439	Biotin carboxylase
CTZ19_12015	COG1063	alcohol dehydrogenase
CTZ19_12025	COG1309	transcriptional regulator
CTZ19_12050	COG0038	chloride channel
CTZ19_12055	COG4770	biotin carboxylase activity
CTZ19_12075	COG1914	H( )-stimulated, divalent metal cation uptake system
CTZ19_12080	COG0583	DNA-binding transcription factor activity
CTZ19_12095	COG3209	COG3209 Rhs family protein
CTZ19_12100	COG3501	Rhs element vgr protein
CTZ19_12135	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTZ19_12155	COG2814	Major facilitator Superfamily
CTZ19_12170	COG1560	Kdo2-lipid A biosynthetic process
CTZ19_12180	COG5006	permease, DMT superfamily
CTZ19_12185	COG1522	sequence-specific DNA binding
CTZ19_12200	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CTZ19_12240	COG1538	Outer membrane efflux protein
CTZ19_12245	COG1137	ATPase activity
CTZ19_12250	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CTZ19_12260	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CTZ19_12265	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CTZ19_12265	COG0517	IMP dehydrogenase activity
CTZ19_12300	COG1733	regulation of RNA biosynthetic process
CTZ19_12305	COG2814	Major facilitator Superfamily
CTZ19_12345	COG1278	Cold shock
CTZ19_12350	COG1280	lysine exporter protein (LysE YggA)
CTZ19_12385	COG1570	exodeoxyribonuclease VII activity
CTZ19_12440	COG0583	DNA-binding transcription factor activity
CTZ19_12445	COG4638	Rieske (2fe-2S)
CTZ19_12450	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CTZ19_12455	COG0543	2 iron, 2 sulfur cluster binding
CTZ19_12455	COG0633	Ferredoxin
CTZ19_12460	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_12465	COG3135	benzoate transporter
CTZ19_12470	COG2814	Major facilitator Superfamily
CTZ19_12485	COG1643	Atp-dependent helicase
CTZ19_12490	COG0450	alkyl hydroperoxide reductase
CTZ19_12500	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CTZ19_12510	COG3634	alkyl hydroperoxide reductase activity
CTZ19_12530	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CTZ19_12535	COG0625	glutathione transferase activity
CTZ19_12545	COG2885	chlorophyll binding
CTZ19_12595	COG1765	OsmC-like protein
CTZ19_12615	COG0667	Aldo Keto reductase
CTZ19_12630	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CTZ19_12640	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CTZ19_12660	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CTZ19_12670	COG3038	cytochrome b561
CTZ19_12675	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CTZ19_12680	COG3316	Transposase and inactivated derivatives
CTZ19_12760	COG3316	Transposase and inactivated derivatives
CTZ19_12765	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CTZ19_12775	COG3316	Transposase and inactivated derivatives
CTZ19_12800	COG3316	Transposase and inactivated derivatives
CTZ19_12805	COG1113	amino acid transport
CTZ19_12825	COG1012	belongs to the aldehyde dehydrogenase family
CTZ19_12845	COG0531	amino acid
CTZ19_12855	COG1113	amino acid transport
CTZ19_12900	COG3209	COG3209 Rhs family protein
CTZ19_12905	COG3501	Rhs element vgr protein
CTZ19_12925	COG4269	membrane
CTZ19_12940	COG1902	pentaerythritol trinitrate reductase activity
CTZ19_12940	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTZ19_12950	COG2203	Gaf domain
CTZ19_12950	COG3706	GGDEF domain
CTZ19_12950	COG4251	negative regulation of phosphorylation
CTZ19_12950	COG5001	Diguanylate cyclase
CTZ19_12960	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CTZ19_12980	COG4172	Belongs to the ABC transporter superfamily
CTZ19_12985	COG4239	(ABC) transporter, permease
CTZ19_12990	COG4174	ABC transporter (Permease)
CTZ19_13000	COG0741	lytic transglycosylase activity
CTZ19_13000	COG1388	LysM domain
CTZ19_13000	COG1388	LysM domain
CTZ19_13000	COG0741	lytic transglycosylase activity
CTZ19_13005	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CTZ19_13045	COG0583	DNA-binding transcription factor activity
CTZ19_13050	COG1279	arginine transmembrane transporter activity
CTZ19_13070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ19_13075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ19_13080	COG0006	proline dipeptidase activity
CTZ19_13115	COG2194	sulfuric ester hydrolase activity
CTZ19_13160	COG0739	heme binding
CTZ19_13525	COG1196	nuclear chromosome segregation
CTZ19_13525	COG0739	heme binding
CTZ19_13525	COG0741	lytic transglycosylase activity
CTZ19_13580	COG4695	Portal protein
CTZ19_13675	COG0305	Participates in initiation and elongation during chromosome replication
CTZ19_13695	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CTZ19_13755	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CTZ19_13780	COG3384	dioxygenase
CTZ19_13790	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CTZ19_13795	COG2878	Part of a membrane complex involved in electron transport
CTZ19_13800	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CTZ19_13825	COG0768	penicillin binding
CTZ19_13830	COG0742	ribosomal rna small subunit methyltransferase
CTZ19_13845	COG0830	nickel cation binding
CTZ19_13855	COG0804	urea catabolic process
CTZ19_13895	COG1253	flavin adenine dinucleotide binding
CTZ19_13905	COG2851	Citrate transporter
CTZ19_13955	COG1773	rubredoxin
CTZ19_13960	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ19_13970	COG0583	DNA-binding transcription factor activity
CTZ19_14000	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CTZ19_14005	COG4181	ATPase activity
CTZ19_14050	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CTZ19_14070	COG0306	phosphate transporter
CTZ19_14080	COG3958	Transketolase
CTZ19_14085	COG3959	Transketolase, thiamine diphosphate binding domain
CTZ19_14090	COG2271	Major facilitator Superfamily
CTZ19_14095	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_14100	COG0583	DNA-binding transcription factor activity
CTZ19_14120	COG2223	nitrite transmembrane transporter activity
CTZ19_14125	COG2207	Transcriptional regulator
CTZ19_14130	COG2066	Belongs to the glutaminase family
CTZ19_14135	COG0242	peptide deformylase activity
CTZ19_14140	COG0477	Major facilitator Superfamily
CTZ19_14150	COG0028	Belongs to the TPP enzyme family
CTZ19_14165	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_14170	COG2267	carboxylic ester hydrolase activity
CTZ19_14180	COG2271	Major facilitator Superfamily
CTZ19_14185	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTZ19_14195	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_14215	COG1414	Transcriptional regulator
CTZ19_14230	COG1024	Enoyl-CoA hydratase
CTZ19_14240	COG1215	transferase activity, transferring glycosyl groups
CTZ19_14245	COG0726	polysaccharide deacetylase
CTZ19_14245	COG1649	PFAM Uncharacterised BCR, COG1649
CTZ19_14255	COG4681	YaeQ
CTZ19_14265	COG0523	cobalamin synthesis protein
CTZ19_14275	COG1607	acyl-coa hydrolase
CTZ19_14285	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTZ19_14290	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTZ19_14295	COG1309	transcriptional regulator
CTZ19_14320	COG2040	homocysteine
CTZ19_14325	COG0531	amino acid
CTZ19_14380	COG1595	DNA-templated transcription, initiation
CTZ19_14390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTZ19_14395	COG0477	Major facilitator Superfamily
CTZ19_14530	COG0592	DNA-directed DNA polymerase activity
CTZ19_14570	COG2026	Addiction module toxin, RelE StbE family
CTZ19_14720	COG3755	Protein conserved in bacteria
CTZ19_14765	COG1484	DNA-dependent DNA replication
CTZ19_14875	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CTZ19_14905	COG0405	Gamma-glutamyltransferase
CTZ19_14910	COG2814	Major facilitator Superfamily
CTZ19_14920	COG2050	protein possibly involved in aromatic compounds catabolism
CTZ19_14935	COG1090	epimerase
CTZ19_14955	COG0420	3'-5' exonuclease activity
CTZ19_14980	COG0735	belongs to the Fur family
CTZ19_14985	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CTZ19_15020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CTZ19_15030	COG0210	DNA helicase
CTZ19_15035	COG2885	chlorophyll binding
CTZ19_15040	COG0204	Acyl-transferase
CTZ19_15055	COG2894	cell division
CTZ19_15080	COG1280	lysine exporter protein (LysE YggA)
CTZ19_15085	COG1674	ftsk spoiiie
CTZ19_15085	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CTZ19_15090	COG0492	ferredoxin-NADP+ reductase activity
CTZ19_15095	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CTZ19_15105	COG0456	acetyltransferase
CTZ19_15165	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CTZ19_15165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CTZ19_15185	COG1012	belongs to the aldehyde dehydrogenase family
CTZ19_15205	COG0473	3-isopropylmalate dehydrogenase activity
CTZ19_15210	COG0583	DNA-binding transcription factor activity
CTZ19_15230	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTZ19_15255	COG0564	pseudouridine synthase activity
CTZ19_15265	COG0358	DNA primase activity
CTZ19_15280	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CTZ19_15310	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CTZ19_15340	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CTZ19_15350	COG0351	phosphomethylpyrimidine kinase
CTZ19_15350	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CTZ19_15350	COG0352	thiamine-phosphate diphosphorylase activity
CTZ19_15355	COG1652	LysM domain
CTZ19_15380	COG1399	metal-binding, possibly nucleic acid-binding protein
CTZ19_15385	COG3101	peptidyl-lysine hydroxylation
CTZ19_15390	COG0009	L-threonylcarbamoyladenylate synthase
CTZ19_15395	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CTZ19_15400	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CTZ19_15415	COG4106	trans-aconitate 2-methyltransferase activity
CTZ19_15430	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTZ19_15430	COG0596	Alpha beta hydrolase
CTZ19_15430	COG2226	methyltransferase
CTZ19_15435	COG1877	trehalose-phosphatase activity
CTZ19_15440	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CTZ19_15445	COG2223	nitrite transmembrane transporter activity
CTZ19_15465	COG1196	nuclear chromosome segregation
CTZ19_15475	COG0730	response to heat
CTZ19_15490	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CTZ19_15500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CTZ19_15555	COG0489	protein tyrosine kinase activity
CTZ19_15565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTZ19_15565	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTZ19_15595	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CTZ19_15600	COG2081	HI0933 family
CTZ19_15610	COG0668	transmembrane transport
CTZ19_15630	COG0583	DNA-binding transcription factor activity
CTZ19_15650	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTZ19_15655	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CTZ19_15685	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CTZ19_15720	COG2205	protein histidine kinase activity
CTZ19_15725	COG0745	RESPONSE REGULATOR receiver
CTZ19_15745	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CTZ19_15755	COG2205	protein histidine kinase activity
CTZ19_15825	COG4993	Dehydrogenase
CTZ19_15845	COG0384	phenazine biosynthesis protein PhzF
CTZ19_15875	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ19_15880	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CTZ19_15890	COG0583	DNA-binding transcription factor activity
CTZ19_15910	COG1473	amidohydrolase
CTZ19_15920	COG0583	DNA-binding transcription factor activity
CTZ19_15940	COG0583	DNA-binding transcription factor activity
CTZ19_15945	COG1053	succinate dehydrogenase
CTZ19_15955	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CTZ19_15960	COG2814	Major facilitator Superfamily
CTZ19_15965	COG1960	acyl-CoA dehydrogenase activity
CTZ19_15970	COG0583	DNA-binding transcription factor activity
CTZ19_15975	COG1063	alcohol dehydrogenase
CTZ19_16005	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CTZ19_16010	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CTZ19_16015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CTZ19_16030	COG3667	copper resistance
CTZ19_16035	COG2132	Multicopper oxidase
CTZ19_16045	COG0561	phosphatase activity
CTZ19_16050	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CTZ19_16075	COG1214	PFAM Peptidase M22, glycoprotease
CTZ19_16125	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CTZ19_16135	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CTZ19_16140	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CTZ19_16145	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CTZ19_16205	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CTZ19_16215	COG1846	Transcriptional regulator
CTZ19_16220	COG1764	response to oxidative stress
CTZ19_16260	COG0037	tRNA processing
CTZ19_16270	COG0248	Ppx GppA phosphatase
CTZ19_16300	COG0072	phenylalanine-tRNA ligase activity
CTZ19_16325	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CTZ19_16340	COG1238	metal cluster binding
CTZ19_16345	COG0625	glutathione transferase activity
CTZ19_16365	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ19_16370	COG3028	Belongs to the UPF0307 family
CTZ19_16375	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTZ19_16395	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CTZ19_16400	COG0617	tRNA 3'-terminal CCA addition
CTZ19_16405	COG1555	photosystem II stabilization
CTZ19_16410	COG3956	TIGRFAM MazG family protein
CTZ19_16420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CTZ19_16440	COG5002	protein histidine kinase activity
CTZ19_16440	COG0784	Response regulator, receiver
CTZ19_16440	COG2205	protein histidine kinase activity
CTZ19_16445	COG1024	Enoyl-CoA hydratase
CTZ19_16450	COG2084	Dehydrogenase
CTZ19_16455	COG3622	Belongs to the hyi family
CTZ19_16470	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CTZ19_16475	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CTZ19_16480	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CTZ19_16485	COG0697	spore germination
CTZ19_16495	COG2814	Major facilitator Superfamily
CTZ19_16500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CTZ19_16510	COG0583	DNA-binding transcription factor activity
CTZ19_16520	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CTZ19_16535	COG0084	hydrolase, TatD family'
CTZ19_16550	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CTZ19_16585	COG0440	acetolactate synthase activity
CTZ19_16590	COG0028	Belongs to the TPP enzyme family
CTZ19_16615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ19_16620	COG1136	(ABC) transporter
CTZ19_16620	COG0577	efflux transmembrane transporter activity
CTZ19_16625	COG1538	Outer membrane efflux protein
CTZ19_16640	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CTZ19_16645	COG1162	GTPase activity
CTZ19_16655	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CTZ19_16675	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CTZ19_16680	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_16720	COG2986	histidine ammonia-lyase
CTZ19_16735	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ19_16745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CTZ19_16750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CTZ19_16790	COG1426	Protein conserved in bacteria
CTZ19_16825	COG0793	Belongs to the peptidase S41A family
CTZ19_16840	COG2267	carboxylic ester hydrolase activity
CTZ19_16850	COG1012	belongs to the aldehyde dehydrogenase family
CTZ19_16855	COG3265	gluconokinase activity
CTZ19_16865	COG0800	Aldolase
CTZ19_16875	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CTZ19_16880	COG0857	belongs to the CobB CobQ family
CTZ19_16880	COG0280	phosphate acetyltransferase
CTZ19_16885	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CTZ19_16885	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CTZ19_16905	COG0740	serine-type endopeptidase activity
CTZ19_16915	COG4774	siderophore transport
CTZ19_16925	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CTZ19_16935	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTZ19_16935	COG2813	Specifically methylates the guanine in position
CTZ19_17035	COG0788	formyltetrahydrofolate deformylase activity
CTZ19_17050	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CTZ19_17055	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CTZ19_17060	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CTZ19_17060	COG4651	solute:proton antiporter activity
CTZ19_17080	COG0724	RNA recognition motif
CTZ19_17085	COG0210	DNA helicase
CTZ19_17110	COG1733	regulation of RNA biosynthetic process
CTZ19_17130	COG1280	lysine exporter protein (LysE YggA)
CTZ19_17135	COG1560	Kdo2-lipid A biosynthetic process
CTZ19_17145	COG1301	dicarboxylic acid transport
CTZ19_17200	COG0473	3-isopropylmalate dehydrogenase activity
CTZ19_17265	COG0583	DNA-binding transcription factor activity
CTZ19_17275	COG0625	glutathione transferase activity
CTZ19_17280	COG2378	regulation of single-species biofilm formation
CTZ19_17285	COG0546	phosphoglycolate phosphatase activity
CTZ19_17300	COG1530	ribonuclease E activity
CTZ19_17320	COG0583	DNA-binding transcription factor activity
CTZ19_17325	COG4221	oxidoreductase activity
CTZ19_17330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CTZ19_17340	COG0534	Mate efflux family protein
CTZ19_17355	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CTZ19_17395	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CTZ19_17400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTZ19_17415	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CTZ19_17425	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CTZ19_17425	COG0644	oxidoreductase
CTZ19_17430	COG0425	Belongs to the sulfur carrier protein TusA family
CTZ19_17435	COG4535	Mg2 and Co2 transporter CorC
CTZ19_17445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTZ19_17465	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CTZ19_17470	COG0475	glutathione-regulated potassium exporter activity
CTZ19_17470	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CTZ19_17475	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CTZ19_17485	COG0484	heat shock protein binding
CTZ19_17490	COG0789	Transcriptional regulator
CTZ19_17495	COG0598	Magnesium transport protein CorA
CTZ19_17515	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CTZ19_17520	COG1074	ATP-dependent DNA helicase activity
CTZ19_17525	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CTZ19_17545	COG2226	methyltransferase
CTZ19_17560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ19_17565	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CTZ19_17580	COG2111	Na H antiporter
CTZ19_17580	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CTZ19_17585	COG1006	Multisubunit Na H antiporter MnhC subunit
CTZ19_17590	COG0651	ATP synthesis coupled electron transport
CTZ19_17600	COG2212	antiporter activity
CTZ19_17620	COG0195	Participates in both transcription termination and antitermination
CTZ19_17670	COG0237	dephospho-CoA kinase activity
CTZ19_17680	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTZ19_17695	COG0497	DNA recombination
CTZ19_17705	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CTZ19_17735	COG2169	Transcriptional regulator
CTZ19_17735	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CTZ19_17740	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CTZ19_17810	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CTZ19_17825	COG0326	Molecular chaperone. Has ATPase activity
CTZ19_17840	COG2056	Na+-H+ antiporter family
CTZ19_17845	COG0596	Alpha beta hydrolase
CTZ19_17940	COG0546	phosphoglycolate phosphatase activity
CTZ19_17945	COG1716	ATPase activity
CTZ19_17990	COG0181	hydroxymethylbilane synthase activity
CTZ19_18000	COG3275	phosphorelay sensor kinase activity
CTZ19_18020	COG1538	Outer membrane efflux protein
CTZ19_18030	COG0697	spore germination
CTZ19_18055	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CTZ19_18060	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CTZ19_18065	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CTZ19_18070	COG0772	Belongs to the SEDS family
CTZ19_18095	COG4974	Belongs to the 'phage' integrase family
CTZ19_18100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CTZ19_18110	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CTZ19_18120	COG2197	response regulator
CTZ19_18135	COG0793	Belongs to the peptidase S41A family
CTZ19_18140	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CTZ19_18145	COG0795	lipopolysaccharide-transporting ATPase activity
CTZ19_18185	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CTZ19_18185	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CTZ19_18195	COG0004	ammonium transporteR
CTZ19_18200	COG0347	Belongs to the P(II) protein family
CTZ19_18210	COG0606	chelatase, subunit chli
CTZ19_18220	COG0659	secondary active sulfate transmembrane transporter activity
CTZ19_18225	COG0589	response to stress
CTZ19_18255	COG0606	chelatase, subunit chli
CTZ19_18260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ19_18270	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTZ19_18285	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CTZ19_18300	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ19_18310	COG0477	Major facilitator Superfamily
CTZ19_18315	COG2860	membrane
CTZ19_18325	COG1253	flavin adenine dinucleotide binding
CTZ19_18345	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CTZ19_18380	COG0655	NAD(P)H dehydrogenase (quinone) activity
CTZ19_18390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CTZ19_18460	COG0758	DNA mediated transformation
CTZ19_18470	COG0697	spore germination
CTZ19_18475	COG1309	transcriptional regulator
CTZ19_18490	COG0386	Belongs to the glutathione peroxidase family
CTZ19_18555	COG1121	(ABC) transporter
CTZ19_18560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CTZ19_18565	COG1280	lysine exporter protein (LysE YggA)
CTZ19_18570	COG2837	iron assimilation
CTZ19_18575	COG0281	malic enzyme
CTZ19_18620	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CTZ19_18620	COG0519	Catalyzes the synthesis of GMP from XMP
CTZ19_18625	COG4399	Belongs to the UPF0754 family
CTZ19_18630	COG2259	Doxx family
CTZ19_18635	COG0586	Pfam SNARE associated Golgi protein
CTZ19_18650	COG1192	Involved in chromosome partitioning
CTZ19_18660	COG0271	Belongs to the BolA IbaG family
CTZ19_18700	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CTZ19_18700	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CTZ19_18700	COG3321	synthase
CTZ19_18700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CTZ19_18705	COG1960	acyl-CoA dehydrogenase activity
CTZ19_18720	COG2197	response regulator
CTZ19_18730	COG3916	Acyl-homoserine-lactone synthase
CTZ19_18735	COG0477	Major facilitator Superfamily
CTZ19_18740	COG1024	Enoyl-CoA hydratase
CTZ19_18745	COG1024	Enoyl-CoA hydratase
CTZ19_18750	COG1960	acyl-CoA dehydrogenase activity
CTZ19_18755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTZ19_18780	COG1113	amino acid transport
CTZ19_18785	COG1113	amino acid transport
CTZ19_18790	COG0251	oxidation-reduction process
CTZ19_18805	COG1522	sequence-specific DNA binding
CTZ19_18830	COG0564	pseudouridine synthase activity
CTZ19_18905	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CTZ19_18920	COG1802	Transcriptional regulator
CTZ19_18930	COG1448	Aminotransferase
CTZ19_18935	COG0277	FAD linked oxidase domain protein
CTZ19_18945	COG2186	Transcriptional regulator
CTZ19_18955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CTZ19_18960	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CTZ19_18975	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CTZ19_18980	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CTZ19_18985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CTZ19_19000	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CTZ19_19045	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CTZ19_19050	COG1596	polysaccharide export
CTZ19_19075	COG0728	peptidoglycan biosynthetic process
CTZ19_19080	COG3023	N-Acetylmuramoyl-L-alanine amidase
CTZ19_19140	COG0546	phosphoglycolate phosphatase activity
CTZ19_19145	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_19165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTZ19_19170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTZ19_19175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTZ19_19180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTZ19_19185	COG1116	anion transmembrane transporter activity
CTZ19_19190	COG1309	transcriptional regulator
CTZ19_19195	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CTZ19_19205	COG0196	riboflavin kinase activity
CTZ19_19210	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CTZ19_19220	COG1047	Peptidyl-prolyl cis-trans
CTZ19_19260	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CTZ19_19315	COG2951	lytic endotransglycosylase activity
CTZ19_19320	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CTZ19_19340	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CTZ19_19350	COG0671	phosphoesterase, PA-phosphatase related
CTZ19_19355	COG0861	Integral membrane protein TerC family
CTZ19_19365	COG0754	glutathionylspermidine amidase activity
CTZ19_19375	COG0402	S-adenosylhomocysteine deaminase activity
CTZ19_19390	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CTZ19_19395	COG1230	cation diffusion facilitator family transporter
CTZ19_19410	COG0706	membrane insertase activity
CTZ19_19425	COG0230	Belongs to the bacterial ribosomal protein bL34 family