locus-tag	class	description
CTZ20_00010	COG0592	DNA-directed DNA polymerase activity
CTZ20_00020	COG0187	DNA topoisomerase II activity
CTZ20_00030	COG0586	Pfam SNARE associated Golgi protein
CTZ20_00035	COG0488	(ABC) transporter
CTZ20_00060	COG0596	Alpha beta hydrolase
CTZ20_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CTZ20_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CTZ20_00165	COG2233	PERMEase
CTZ20_00180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ20_00215	COG2814	Major facilitator Superfamily
CTZ20_00220	COG0656	L-ascorbic acid biosynthetic process
CTZ20_00225	COG0583	DNA-binding transcription factor activity
CTZ20_00240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ20_00245	COG1064	alcohol dehydrogenase
CTZ20_00250	COG2818	Glycosylase
CTZ20_00265	COG1194	a g-specific adenine glycosylase
CTZ20_00285	COG2983	Belongs to the UPF0260 family
CTZ20_00290	COG2133	pyrroloquinoline quinone binding
CTZ20_00295	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CTZ20_00300	COG2116	formate transmembrane transporter activity
CTZ20_00320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTZ20_00325	COG1335	isochorismatase
CTZ20_00330	COG0385	Bile acid
CTZ20_00335	COG0534	Mate efflux family protein
CTZ20_00340	COG1683	Conserved Protein
CTZ20_00360	COG0625	glutathione transferase activity
CTZ20_00370	COG1113	amino acid transport
CTZ20_00380	COG0523	cobalamin synthesis protein
CTZ20_00390	COG2188	Transcriptional regulator
CTZ20_00420	COG0010	Belongs to the arginase family
CTZ20_00435	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CTZ20_00440	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CTZ20_00450	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CTZ20_00455	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CTZ20_00560	COG0534	Mate efflux family protein
CTZ20_00565	COG0436	Aminotransferase
CTZ20_00570	COG2733	membrane
CTZ20_00585	COG2918	glutathione biosynthetic process
CTZ20_00595	COG3501	Rhs element vgr protein
CTZ20_00600	COG1388	LysM domain
CTZ20_00600	COG0791	NLP P60 protein
CTZ20_00615	COG3150	esterase
CTZ20_00625	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_00630	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CTZ20_00640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ20_00650	COG2233	PERMEase
CTZ20_00655	COG2351	hydroxyisourate hydrolase activity
CTZ20_00690	COG3706	GGDEF domain
CTZ20_00705	COG1393	Belongs to the ArsC family
CTZ20_00710	COG0708	Exodeoxyribonuclease III
CTZ20_00730	COG0189	ligase activity
CTZ20_00750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CTZ20_00760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CTZ20_00775	COG4942	peptidase
CTZ20_00785	COG0508	dehydrogenase complex catalyzes the overall conversion of
CTZ20_00795	COG2119	membrane
CTZ20_00800	COG4774	siderophore transport
CTZ20_00805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ20_00805	COG0426	domain, Protein
CTZ20_00830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CTZ20_00850	COG1902	pentaerythritol trinitrate reductase activity
CTZ20_00855	COG1519	Transferase
CTZ20_00860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CTZ20_00865	COG0668	transmembrane transport
CTZ20_00880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTZ20_00885	COG1335	isochorismatase
CTZ20_00890	COG1522	sequence-specific DNA binding
CTZ20_00895	COG3328	transposase activity
CTZ20_00920	COG2205	protein histidine kinase activity
CTZ20_00920	COG2198	Histidine kinase
CTZ20_00920	COG0784	Response regulator, receiver
CTZ20_00925	COG3162	membrane
CTZ20_00930	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CTZ20_00940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTZ20_00950	COG3706	GGDEF domain
CTZ20_00960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CTZ20_00965	COG1309	transcriptional regulator
CTZ20_00985	COG0351	phosphomethylpyrimidine kinase
CTZ20_00985	COG0352	thiamine-phosphate diphosphorylase activity
CTZ20_00985	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CTZ20_00995	COG2814	Major facilitator Superfamily
CTZ20_01010	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CTZ20_01020	COG1113	amino acid transport
CTZ20_01030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CTZ20_01035	COG1012	belongs to the aldehyde dehydrogenase family
CTZ20_01045	COG1335	isochorismatase
CTZ20_01075	COG2814	Major facilitator Superfamily
CTZ20_01080	COG0583	DNA-binding transcription factor activity
CTZ20_01100	COG0667	Aldo Keto reductase
CTZ20_01135	COG1733	regulation of RNA biosynthetic process
CTZ20_01145	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTZ20_01210	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CTZ20_01225	COG2329	Antibiotic biosynthesis monooxygenase
CTZ20_01255	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CTZ20_01285	COG0427	acetyl-CoA hydrolase
CTZ20_01300	COG0745	RESPONSE REGULATOR receiver
CTZ20_01310	COG0659	secondary active sulfate transmembrane transporter activity
CTZ20_01315	COG4221	oxidoreductase activity
CTZ20_01325	COG0488	(ABC) transporter
CTZ20_01410	COG0833	amino acid
CTZ20_01455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CTZ20_01460	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CTZ20_01475	COG2226	methyltransferase
CTZ20_01525	COG0070	glutamate synthase
CTZ20_01525	COG0069	glutamate synthase activity
CTZ20_01525	COG0067	glutamate synthase
CTZ20_01530	COG0493	'glutamate synthase
CTZ20_01540	COG1704	LemA family
CTZ20_01545	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CTZ20_01565	COG3307	-O-antigen
CTZ20_01585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CTZ20_01595	COG0194	GDP metabolic process
CTZ20_01645	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CTZ20_01665	COG5380	lipid catabolic process
CTZ20_01670	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CTZ20_01695	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CTZ20_01700	COG0277	FAD linked oxidase domain protein
CTZ20_01710	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CTZ20_01715	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTZ20_01730	COG1289	transmembrane transporter activity
CTZ20_01740	COG0628	permease
CTZ20_01745	COG1192	Involved in chromosome partitioning
CTZ20_01775	COG0833	amino acid
CTZ20_01780	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CTZ20_01785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CTZ20_01795	COG1012	belongs to the aldehyde dehydrogenase family
CTZ20_01835	COG0583	DNA-binding transcription factor activity
CTZ20_01880	COG0517	IMP dehydrogenase activity
CTZ20_01885	COG1983	PspC domain protein
CTZ20_01895	COG1960	acyl-CoA dehydrogenase activity
CTZ20_01910	COG0408	coproporphyrinogen oxidase activity
CTZ20_01930	COG0513	Belongs to the DEAD box helicase family
CTZ20_01935	COG1127	ABC transporter
CTZ20_01940	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CTZ20_01950	COG2854	intermembrane phospholipid transfer
CTZ20_01960	COG0598	Magnesium transport protein CorA
CTZ20_01970	COG0494	nUDIX hydrolase
CTZ20_01975	COG1040	competence protein
CTZ20_01980	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CTZ20_02000	COG1946	Acyl-CoA thioesterase
CTZ20_02005	COG1301	dicarboxylic acid transport
CTZ20_02020	COG1959	2 iron, 2 sulfur cluster binding
CTZ20_02025	COG1017	nitric oxide dioxygenase activity
CTZ20_02025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTZ20_02030	COG0433	COG0433 Predicted ATPase
CTZ20_02035	COG0626	cystathionine gamma-synthase activity
CTZ20_02155	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CTZ20_02165	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CTZ20_02190	COG1960	acyl-CoA dehydrogenase activity
CTZ20_02195	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CTZ20_02225	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CTZ20_02230	COG0339	signal peptide processing
CTZ20_02235	COG0557	exoribonuclease II activity
CTZ20_02280	COG0179	Fumarylacetoacetate (FAA) hydrolase
CTZ20_02285	COG2169	Transcriptional regulator
CTZ20_02290	COG0697	spore germination
CTZ20_02295	COG1295	ribonuclease BN
CTZ20_02330	COG1702	phosphate starvation-inducible protein PhoH
CTZ20_02340	COG0739	heme binding
CTZ20_02340	COG0741	lytic transglycosylase activity
CTZ20_02340	COG1196	nuclear chromosome segregation
CTZ20_02370	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CTZ20_02375	COG1183	phosphatidylcholine synthase activity
CTZ20_02420	COG1960	acyl-CoA dehydrogenase activity
CTZ20_02425	COG1309	transcriptional regulator
CTZ20_02440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CTZ20_02445	COG1960	acyl-CoA dehydrogenase activity
CTZ20_02465	COG2969	positive regulation of protein catabolic process
CTZ20_02475	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CTZ20_02490	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CTZ20_02495	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CTZ20_02515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CTZ20_02525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CTZ20_02530	COG1408	metallophosphoesterase
CTZ20_02540	COG2199	diguanylate cyclase activity
CTZ20_02585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTZ20_02585	COG3453	Protein conserved in bacteria
CTZ20_02600	COG1607	acyl-coa hydrolase
CTZ20_02630	COG2350	Protein conserved in bacteria
CTZ20_02640	COG0613	PHP domain protein
CTZ20_02645	COG3781	membrane
CTZ20_02655	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CTZ20_02660	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CTZ20_02670	COG1862	Preprotein translocase
CTZ20_02700	COG2205	protein histidine kinase activity
CTZ20_02705	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CTZ20_02725	COG0726	polysaccharide deacetylase
CTZ20_02730	COG0463	Glycosyl transferase, family 2
CTZ20_02735	COG0438	transferase activity, transferring glycosyl groups
CTZ20_02800	COG0625	glutathione transferase activity
CTZ20_02805	COG0583	DNA-binding transcription factor activity
CTZ20_02810	COG1960	acyl-CoA dehydrogenase activity
CTZ20_02815	COG1960	acyl-CoA dehydrogenase activity
CTZ20_02825	COG2205	protein histidine kinase activity
CTZ20_02830	COG0745	RESPONSE REGULATOR receiver
CTZ20_02835	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CTZ20_02855	COG2096	Adenosyltransferase
CTZ20_02870	COG0133	tryptophan synthase activity
CTZ20_02905	COG0285	dihydrofolate synthase activity
CTZ20_02925	COG0450	alkyl hydroperoxide reductase
CTZ20_02940	COG0477	Major facilitator Superfamily
CTZ20_02945	COG1272	protein, Hemolysin III
CTZ20_02975	COG0183	Belongs to the thiolase family
CTZ20_02980	COG2207	Transcriptional regulator
CTZ20_03000	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ20_03020	COG0183	Belongs to the thiolase family
CTZ20_03030	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CTZ20_03030	COG2885	chlorophyll binding
CTZ20_03040	COG1690	Belongs to the RtcB family
CTZ20_03045	COG0833	amino acid
CTZ20_03055	COG2233	PERMEase
CTZ20_03085	COG2094	Belongs to the DNA glycosylase MPG family
CTZ20_03090	COG4772	TonB-dependent receptor
CTZ20_03105	COG1902	pentaerythritol trinitrate reductase activity
CTZ20_03110	COG0679	Auxin Efflux Carrier
CTZ20_03120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CTZ20_03125	COG0354	folic acid binding
CTZ20_03135	COG3189	MarR family transcriptional regulator
CTZ20_03140	COG2824	Alkylphosphonate utilization operon protein PhnA
CTZ20_03145	COG3422	double-strand break repair
CTZ20_03185	COG0840	transmembrane signaling receptor activity
CTZ20_03205	COG5510	response to toxic substance
CTZ20_03215	COG2832	Protein of unknown function (DUF454)
CTZ20_03220	COG1376	ErfK ybiS ycfS ynhG family protein
CTZ20_03270	COG1289	transmembrane transporter activity
CTZ20_03275	COG2814	Major facilitator Superfamily
CTZ20_03295	COG1115	amino acid carrier protein
CTZ20_03300	COG1752	Esterase of the alpha-beta hydrolase superfamily
CTZ20_03305	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CTZ20_03310	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CTZ20_03340	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CTZ20_03350	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CTZ20_03355	COG1077	Cell shape determining protein MreB Mrl
CTZ20_03360	COG1792	Involved in formation and maintenance of cell shape
CTZ20_03365	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CTZ20_03370	COG0424	maF-like protein
CTZ20_03375	COG1530	ribonuclease E activity
CTZ20_03385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ20_03405	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTZ20_03430	COG2207	Transcriptional regulator
CTZ20_03450	COG1113	amino acid transport
CTZ20_03455	COG2828	Protein conserved in bacteria
CTZ20_03460	COG0142	geranyltranstransferase activity
CTZ20_03465	COG2315	Protein conserved in bacteria
CTZ20_03480	COG1752	Esterase of the alpha-beta hydrolase superfamily
CTZ20_03500	COG2194	sulfuric ester hydrolase activity
CTZ20_03505	COG0745	RESPONSE REGULATOR receiver
CTZ20_03510	COG0642	Histidine kinase
CTZ20_03520	COG0004	ammonium transporteR
CTZ20_03530	COG0583	DNA-binding transcription factor activity
CTZ20_03550	COG0525	valine-tRNA ligase activity
CTZ20_03560	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_03570	COG0393	Putative heavy-metal-binding
CTZ20_03575	COG0393	Putative heavy-metal-binding
CTZ20_03580	COG1538	Outer membrane efflux protein
CTZ20_03590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ20_03595	COG0671	phosphoesterase, PA-phosphatase related
CTZ20_03625	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CTZ20_03640	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CTZ20_03640	COG1648	precorrin-2 dehydrogenase activity
CTZ20_03645	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CTZ20_03650	COG1733	regulation of RNA biosynthetic process
CTZ20_03660	COG0531	amino acid
CTZ20_03675	COG0321	lipoyl(octanoyl) transferase activity
CTZ20_03680	COG2921	Belongs to the UPF0250 family
CTZ20_03720	COG2009	succinate dehydrogenase
CTZ20_03725	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CTZ20_03730	COG1053	succinate dehydrogenase
CTZ20_03735	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CTZ20_03760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTZ20_03780	COG2354	Protein conserved in bacteria
CTZ20_03785	COG2321	neutral zinc metallopeptidase
CTZ20_03815	COG2843	Capsule synthesis protein
CTZ20_03830	COG0589	response to stress
CTZ20_03850	COG0505	Belongs to the CarA family
CTZ20_03880	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CTZ20_03885	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CTZ20_03935	COG0477	Major facilitator Superfamily
CTZ20_03940	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CTZ20_03960	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CTZ20_03990	COG0584	glycerophosphoryl diester phosphodiesterase
CTZ20_04010	COG0741	lytic transglycosylase activity
CTZ20_04035	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CTZ20_04050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ20_04075	COG0778	Nitroreductase
CTZ20_04090	COG1929	Belongs to the glycerate kinase type-1 family
CTZ20_04095	COG0243	molybdopterin cofactor binding
CTZ20_04100	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CTZ20_04105	COG3339	Conserved Protein
CTZ20_04115	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CTZ20_04130	COG1113	amino acid transport
CTZ20_04140	COG0019	diaminopimelate decarboxylase activity
CTZ20_04150	COG1280	lysine exporter protein (LysE YggA)
CTZ20_04155	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CTZ20_04185	COG0463	Glycosyl transferase, family 2
CTZ20_04205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ20_04235	COG4591	ABC-type transport system involved in lipoprotein release permease component
CTZ20_04240	COG1136	(ABC) transporter
CTZ20_04245	COG2333	competence protein COMEC
CTZ20_04245	COG0658	competence protein
CTZ20_04255	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CTZ20_04255	COG0616	signal peptide processing
CTZ20_04260	COG0596	Alpha beta hydrolase
CTZ20_04265	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CTZ20_04275	COG0628	permease
CTZ20_04310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTZ20_04330	COG0823	Involved in the tonB-independent uptake of proteins
CTZ20_04350	COG0824	Thioesterase
CTZ20_04355	COG1473	amidohydrolase
CTZ20_04375	COG0047	phosphoribosylformylglycinamidine synthase activity
CTZ20_04375	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CTZ20_04380	COG2814	Major facilitator Superfamily
CTZ20_04385	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CTZ20_04390	COG1024	Enoyl-CoA hydratase
CTZ20_04395	COG1056	cytidyltransferase-related domain
CTZ20_04395	COG1051	belongs to the nudix hydrolase family
CTZ20_04405	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CTZ20_04420	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CTZ20_04435	COG4625	pathogenesis
CTZ20_04440	COG0583	DNA-binding transcription factor activity
CTZ20_04445	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CTZ20_04450	COG4208	sulfate ABC transporter
CTZ20_04455	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CTZ20_04465	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CTZ20_04470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CTZ20_04475	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CTZ20_04495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTZ20_04510	COG0681	Belongs to the peptidase S26 family
CTZ20_04525	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CTZ20_04535	COG1381	Involved in DNA repair and RecF pathway recombination
CTZ20_04540	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CTZ20_04550	COG4221	oxidoreductase activity
CTZ20_04600	COG0556	nucleotide-excision repair
CTZ20_04795	COG5410	chromosome segregation
CTZ20_04985	COG2070	2-Nitropropane dioxygenase
CTZ20_05015	COG1215	transferase activity, transferring glycosyl groups
CTZ20_05030	COG0415	Belongs to the DNA photolyase family
CTZ20_05040	COG1252	NADH dehydrogenase
CTZ20_05045	COG1686	Belongs to the peptidase S11 family
CTZ20_05060	COG1187	pseudouridine synthase activity
CTZ20_05085	COG0477	Major facilitator Superfamily
CTZ20_05090	COG0583	DNA-binding transcription factor activity
CTZ20_05105	COG0612	Peptidase, M16
CTZ20_05130	COG0352	thiamine-phosphate diphosphorylase activity
CTZ20_05165	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTZ20_05180	COG1309	transcriptional regulator
CTZ20_05190	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CTZ20_05195	COG0076	glutamate decarboxylase activity
CTZ20_05205	COG1522	sequence-specific DNA binding
CTZ20_05210	COG3961	Belongs to the TPP enzyme family
CTZ20_05215	COG1113	amino acid transport
CTZ20_05220	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CTZ20_05225	COG0573	inorganic phosphate transmembrane transporter activity
CTZ20_05235	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CTZ20_05240	COG0616	signal peptide processing
CTZ20_05275	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CTZ20_05280	COG1686	Belongs to the peptidase S11 family
CTZ20_05305	COG0583	DNA-binding transcription factor activity
CTZ20_05310	COG1067	ATP-dependent peptidase activity
CTZ20_05355	COG1966	Carbon starvation protein
CTZ20_05360	COG2879	small protein
CTZ20_05395	COG2508	Transcriptional regulator
CTZ20_05395	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CTZ20_05415	COG1113	amino acid transport
CTZ20_05420	COG0583	DNA-binding transcription factor activity
CTZ20_05425	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTZ20_05430	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTZ20_05445	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ20_05450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTZ20_05450	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CTZ20_05485	COG2814	Major facilitator Superfamily
CTZ20_05490	COG4948	Mandelate Racemase Muconate Lactonizing
CTZ20_05500	COG1309	transcriptional regulator
CTZ20_05520	COG1741	Belongs to the pirin family
CTZ20_05530	COG2964	Protein conserved in bacteria
CTZ20_05545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ20_05550	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTZ20_05555	COG4605	iron ion homeostasis
CTZ20_05560	COG4604	ABC transporter, ATP-binding protein
CTZ20_05590	COG3433	isochorismatase activity
CTZ20_05590	COG1535	isochorismatase
CTZ20_05605	COG1132	(ABC) transporter
CTZ20_05615	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CTZ20_05625	COG1169	isochorismate synthase
CTZ20_05640	COG3739	integral membrane protein
CTZ20_05675	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CTZ20_05705	COG0308	aminopeptidase N
CTZ20_05710	COG0512	Glutamine amidotransferase of anthranilate synthase
CTZ20_05720	COG3104	oligopeptide transport
CTZ20_05735	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CTZ20_05770	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CTZ20_05775	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CTZ20_05780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTZ20_05800	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CTZ20_05805	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CTZ20_05810	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CTZ20_05825	COG1960	acyl-CoA dehydrogenase activity
CTZ20_05830	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CTZ20_05835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTZ20_05845	COG2223	nitrite transmembrane transporter activity
CTZ20_05855	COG0024	Methionine aminopeptidase
CTZ20_05860	COG0052	Belongs to the universal ribosomal protein uS2 family
CTZ20_05875	COG2207	Transcriptional regulator
CTZ20_05900	COG2951	lytic endotransglycosylase activity
CTZ20_05905	COG0772	Belongs to the SEDS family
CTZ20_05920	COG0842	Transport permease protein
CTZ20_05925	COG1131	(ABC) transporter
CTZ20_05960	COG1538	Outer membrane efflux protein
CTZ20_05970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ20_05985	COG4215	(ABC) transporter
CTZ20_05990	COG4160	amino acid transport
CTZ20_05995	COG4598	ABC transporter
CTZ20_06005	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTZ20_06015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ20_06030	COG1720	tRNA m6t6A37 methyltransferase activity
CTZ20_06050	COG0745	RESPONSE REGULATOR receiver
CTZ20_06055	COG0642	Histidine kinase
CTZ20_06065	COG0494	nUDIX hydrolase
CTZ20_06075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CTZ20_06080	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CTZ20_06085	COG3139	Protein of unknown function (DUF1315)
CTZ20_06090	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CTZ20_06100	COG1301	dicarboxylic acid transport
CTZ20_06105	COG1960	acyl-CoA dehydrogenase activity
CTZ20_06110	COG2819	hydrolase of the alpha beta superfamily
CTZ20_06120	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CTZ20_06130	COG2195	Cleaves the N-terminal amino acid of tripeptides
CTZ20_06135	COG1234	tRNA 3'-trailer cleavage
CTZ20_06165	COG2363	Small membrane protein
CTZ20_06185	COG0513	Belongs to the DEAD box helicase family
CTZ20_06195	COG0778	Nitroreductase
CTZ20_06225	COG1286	toxin biosynthetic process
CTZ20_06250	COG4783	chaperone-mediated protein folding
CTZ20_06255	COG1610	YqeY-like protein
CTZ20_06260	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CTZ20_06355	COG3111	PFAM Bacterial OB fold (BOF) protein
CTZ20_06380	COG3243	poly(R)-hydroxyalkanoic acid synthase
CTZ20_06385	COG0786	glutamate:sodium symporter activity
CTZ20_06395	COG2186	Transcriptional regulator
CTZ20_06445	COG0477	Major facilitator Superfamily
CTZ20_06475	COG2985	domain, Protein
CTZ20_06485	COG2995	paraquat-inducible protein a
CTZ20_06495	COG3316	Transposase and inactivated derivatives
CTZ20_06500	COG2011	ABC-type metal ion transport system permease component
CTZ20_06505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTZ20_06520	COG3316	Transposase and inactivated derivatives
CTZ20_06530	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CTZ20_06535	COG1464	Belongs to the NlpA lipoprotein family
CTZ20_06540	COG0151	Belongs to the GarS family
CTZ20_06545	COG0138	bifunctional purine biosynthesis protein purh
CTZ20_06550	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CTZ20_06580	COG2308	Evidence 4 Homologs of previously reported genes of
CTZ20_06590	COG1305	Transglutaminase-like
CTZ20_06600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CTZ20_06605	COG0305	Participates in initiation and elongation during chromosome replication
CTZ20_06630	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CTZ20_06640	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CTZ20_06645	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CTZ20_06670	COG1649	PFAM Uncharacterised BCR, COG1649
CTZ20_06670	COG0726	polysaccharide deacetylase
CTZ20_06675	COG1215	transferase activity, transferring glycosyl groups
CTZ20_06690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTZ20_06710	COG0583	DNA-binding transcription factor activity
CTZ20_06730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTZ20_06735	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTZ20_06750	COG1960	acyl-CoA dehydrogenase activity
CTZ20_06755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTZ20_06760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ20_06785	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CTZ20_06790	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CTZ20_06800	COG2205	protein histidine kinase activity
CTZ20_06805	COG0745	RESPONSE REGULATOR receiver
CTZ20_06810	COG0174	glutamine synthetase
CTZ20_06830	COG0729	surface antigen
CTZ20_06860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CTZ20_06865	COG2814	Major facilitator Superfamily
CTZ20_06880	COG0583	DNA-binding transcription factor activity
CTZ20_06895	COG1187	pseudouridine synthase activity
CTZ20_06915	COG0802	atpase or kinase
CTZ20_06920	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CTZ20_06930	COG1923	regulation of RNA biosynthetic process
CTZ20_06935	COG0697	spore germination
CTZ20_06950	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTZ20_06965	COG0519	Catalyzes the synthesis of GMP from XMP
CTZ20_06965	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CTZ20_06970	COG4302	ethanolamine ammonia-lyase activity
CTZ20_06975	COG4303	Ethanolamine ammonia lyase large subunit
CTZ20_06980	COG0531	amino acid
CTZ20_07000	COG1454	alcohol dehydrogenase
CTZ20_07005	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CTZ20_07015	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CTZ20_07035	COG0308	aminopeptidase N
CTZ20_07045	COG4221	oxidoreductase activity
CTZ20_07055	COG1605	Chorismate mutase
CTZ20_07075	COG1309	transcriptional regulator
CTZ20_07085	COG0668	transmembrane transport
CTZ20_07120	COG4773	Receptor
CTZ20_07140	COG0488	(ABC) transporter
CTZ20_07145	COG0589	response to stress
CTZ20_07165	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CTZ20_07175	COG3135	benzoate transporter
CTZ20_07180	COG1522	sequence-specific DNA binding
CTZ20_07195	COG0583	DNA-binding transcription factor activity
CTZ20_07205	COG0183	Belongs to the thiolase family
CTZ20_07235	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CTZ20_07245	COG0824	Thioesterase
CTZ20_07250	COG1454	alcohol dehydrogenase
CTZ20_07260	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CTZ20_07280	COG0069	glutamate synthase activity
CTZ20_07440	COG5410	chromosome segregation
CTZ20_07565	COG0739	heme binding
CTZ20_07635	COG2814	Major facilitator Superfamily
CTZ20_07650	COG0511	ligase activity, forming carbon-carbon bonds
CTZ20_07665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTZ20_07665	COG1116	anion transmembrane transporter activity
CTZ20_07670	COG0745	RESPONSE REGULATOR receiver
CTZ20_07680	COG2146	nitrite reductase [NAD(P)H] activity
CTZ20_07680	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ20_07685	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ20_07690	COG0243	molybdopterin cofactor binding
CTZ20_07700	COG0243	molybdopterin cofactor binding
CTZ20_07705	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CTZ20_07720	COG0521	Mo-molybdopterin cofactor biosynthetic process
CTZ20_07720	COG0315	cyclic pyranopterin monophosphate synthase activity
CTZ20_07725	COG0303	'Molybdopterin
CTZ20_07735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ20_07740	COG0697	spore germination
CTZ20_07760	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CTZ20_07765	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CTZ20_07825	COG2204	response regulator
CTZ20_07830	COG3852	Histidine kinase
CTZ20_07850	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CTZ20_07855	COG0575	Belongs to the CDS family
CTZ20_07890	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTZ20_07905	COG2137	regulation of response to DNA damage stimulus
CTZ20_07915	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CTZ20_07920	COG1011	Hydrolase
CTZ20_07945	COG1522	sequence-specific DNA binding
CTZ20_07955	COG1113	amino acid transport
CTZ20_07975	COG0659	secondary active sulfate transmembrane transporter activity
CTZ20_07980	COG2135	peptidase activity
CTZ20_07995	COG3300	MHYT domain
CTZ20_07995	COG5001	Diguanylate cyclase
CTZ20_08015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTZ20_08015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTZ20_08015	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CTZ20_08020	COG1105	Belongs to the carbohydrate kinase PfkB family
CTZ20_08025	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CTZ20_08025	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTZ20_08055	COG0024	Methionine aminopeptidase
CTZ20_08060	COG0583	DNA-binding transcription factor activity
CTZ20_08070	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CTZ20_08075	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CTZ20_08080	COG0517	IMP dehydrogenase activity
CTZ20_08080	COG0516	GMP reductase activity
CTZ20_08105	COG0552	protein localization to endoplasmic reticulum
CTZ20_08115	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CTZ20_08130	COG4890	Cyd operon protein YbgT
CTZ20_08135	COG1294	oxidase, subunit
CTZ20_08155	COG1585	Membrane protein implicated in regulation of membrane protease activity
CTZ20_08165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CTZ20_08170	COG4774	siderophore transport
CTZ20_08185	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CTZ20_08190	COG0569	domain protein
CTZ20_08195	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CTZ20_08225	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CTZ20_08230	COG0542	response to heat
CTZ20_08240	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CTZ20_08255	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTZ20_08255	COG1902	pentaerythritol trinitrate reductase activity
CTZ20_08300	COG2323	membrane
CTZ20_08305	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CTZ20_08315	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CTZ20_08320	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTZ20_08325	COG0183	Belongs to the thiolase family
CTZ20_08330	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CTZ20_08335	COG0596	Alpha beta hydrolase
CTZ20_08340	COG2271	Major facilitator Superfamily
CTZ20_08345	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTZ20_08350	COG3485	protocatechuate 3,4-dioxygenase
CTZ20_08355	COG3485	protocatechuate 3,4-dioxygenase
CTZ20_08360	COG0710	3-dehydroquinate dehydratase activity
CTZ20_08365	COG3420	alginic acid biosynthetic process
CTZ20_08370	COG3659	wide pore channel activity
CTZ20_08375	COG4993	Dehydrogenase
CTZ20_08385	COG2391	methyltransferase activity
CTZ20_08400	COG1414	Transcriptional regulator
CTZ20_08405	COG0583	DNA-binding transcription factor activity
CTZ20_08410	COG1960	acyl-CoA dehydrogenase activity
CTZ20_08435	COG2814	Major facilitator Superfamily
CTZ20_08445	COG0154	amidase activity
CTZ20_08465	COG4638	Rieske (2fe-2S)
CTZ20_08475	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_08485	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ20_08495	COG3733	amine oxidase
CTZ20_08505	COG1012	belongs to the aldehyde dehydrogenase family
CTZ20_08515	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTZ20_08520	COG0183	Belongs to the thiolase family
CTZ20_08525	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTZ20_08530	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CTZ20_08540	COG4829	muconolactone delta-isomerase
CTZ20_08545	COG4948	Mandelate Racemase Muconate Lactonizing
CTZ20_08550	COG0583	DNA-binding transcription factor activity
CTZ20_08560	COG2186	Transcriptional regulator
CTZ20_08580	COG1012	belongs to the aldehyde dehydrogenase family
CTZ20_08600	COG1960	acyl-CoA dehydrogenase activity
CTZ20_08605	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_08610	COG3829	transcription factor binding
CTZ20_08620	COG3162	membrane
CTZ20_08635	COG1012	belongs to the aldehyde dehydrogenase family
CTZ20_08650	COG0753	catalase activity
CTZ20_08675	COG1846	Transcriptional regulator
CTZ20_08680	COG1902	pentaerythritol trinitrate reductase activity
CTZ20_08680	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTZ20_08690	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CTZ20_08720	COG1309	transcriptional regulator
CTZ20_08730	COG1335	isochorismatase
CTZ20_08735	COG0583	DNA-binding transcription factor activity
CTZ20_08745	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CTZ20_08745	COG0475	glutathione-regulated potassium exporter activity
CTZ20_08755	COG1473	amidohydrolase
CTZ20_08770	COG2831	hemolysin activation secretion protein
CTZ20_08775	COG3210	domain, Protein
CTZ20_08820	COG0583	DNA-binding transcription factor activity
CTZ20_08845	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CTZ20_08850	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CTZ20_08870	COG1566	PFAM secretion protein HlyD family protein
CTZ20_08885	COG1012	belongs to the aldehyde dehydrogenase family
CTZ20_08890	COG0129	dihydroxy-acid dehydratase activity
CTZ20_08900	COG0583	DNA-binding transcription factor activity
CTZ20_08905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CTZ20_08915	COG2084	Dehydrogenase
CTZ20_08920	COG2207	Transcriptional regulator
CTZ20_08935	COG1064	alcohol dehydrogenase
CTZ20_08950	COG1120	ATPase activity
CTZ20_08970	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CTZ20_09090	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CTZ20_09140	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_09155	COG2207	Transcriptional regulator
CTZ20_09165	COG2205	protein histidine kinase activity
CTZ20_09170	COG0745	RESPONSE REGULATOR receiver
CTZ20_09180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ20_09185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTZ20_09190	COG1538	Outer membrane efflux protein
CTZ20_09200	COG2072	flavoprotein involved in K transport
CTZ20_09220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTZ20_09240	COG3539	Fimbrial protein
CTZ20_09270	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CTZ20_09280	COG0753	catalase activity
CTZ20_09295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CTZ20_09360	COG3433	isochorismatase activity
CTZ20_09360	COG1535	isochorismatase
CTZ20_09365	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_09370	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CTZ20_09375	COG4149	molybdate abc transporter
CTZ20_09380	COG0725	ABC transporter, periplasmic molybdate-binding protein
CTZ20_09390	COG4638	Rieske (2fe-2S)
CTZ20_09395	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CTZ20_09400	COG0543	2 iron, 2 sulfur cluster binding
CTZ20_09400	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTZ20_09415	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ20_09425	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_09430	COG0412	Dienelactone hydrolase
CTZ20_09440	COG2207	Transcriptional regulator
CTZ20_09450	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_09455	COG2610	gluconate transmembrane transporter activity
CTZ20_09465	COG0583	DNA-binding transcription factor activity
CTZ20_09475	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTZ20_09480	COG2031	fatty acid transporter
CTZ20_09485	COG0183	Belongs to the thiolase family
CTZ20_09490	COG0583	DNA-binding transcription factor activity
CTZ20_09495	COG0583	DNA-binding transcription factor activity
CTZ20_09510	COG1027	Aspartate ammonia-lyase
CTZ20_09520	COG0477	Major facilitator Superfamily
CTZ20_09540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTZ20_09545	COG4521	taurine ABC transporter
CTZ20_09570	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CTZ20_09575	COG1733	regulation of RNA biosynthetic process
CTZ20_09580	COG2207	Transcriptional regulator
CTZ20_09580	COG3708	Transcriptional regulator
CTZ20_09595	COG0730	response to heat
CTZ20_09605	COG3453	Protein conserved in bacteria
CTZ20_09605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTZ20_09615	COG3781	membrane
CTZ20_09620	COG1063	alcohol dehydrogenase
CTZ20_09630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTZ20_09635	COG0508	dehydrogenase complex catalyzes the overall conversion of
CTZ20_09640	COG0022	dehydrogenase e1 component
CTZ20_09645	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CTZ20_09650	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CTZ20_09665	COG3706	GGDEF domain
CTZ20_09680	COG0133	tryptophan synthase activity
CTZ20_09690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CTZ20_09725	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CTZ20_09750	COG2226	methyltransferase
CTZ20_09805	COG0842	Transport permease protein
CTZ20_09810	COG0842	Transport permease protein
CTZ20_09815	COG1131	(ABC) transporter
CTZ20_09830	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTZ20_09835	COG4773	Receptor
CTZ20_09855	COG0730	response to heat
CTZ20_09860	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CTZ20_09880	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CTZ20_09935	COG4264	IucA IucC family
CTZ20_09940	COG4264	IucA IucC family
CTZ20_09960	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CTZ20_09975	COG1960	acyl-CoA dehydrogenase activity
CTZ20_09980	COG1960	acyl-CoA dehydrogenase activity
CTZ20_09985	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTZ20_09990	COG2207	Transcriptional regulator
CTZ20_09995	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CTZ20_10000	COG0776	regulation of translation
CTZ20_10025	COG0822	iron-sulfur transferase activity
CTZ20_10030	COG0316	Belongs to the HesB IscA family
CTZ20_10060	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CTZ20_10080	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CTZ20_10085	COG0702	epimerase
CTZ20_10120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTZ20_10130	COG0339	signal peptide processing
CTZ20_10175	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CTZ20_10180	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CTZ20_10210	COG0776	regulation of translation
CTZ20_10230	COG0590	tRNA wobble adenosine to inosine editing
CTZ20_10260	COG2165	general secretion pathway protein
CTZ20_10275	COG0084	hydrolase, TatD family'
CTZ20_10295	COG1663	tetraacyldisaccharide 4'-kinase activity
CTZ20_10300	COG1132	(ABC) transporter
CTZ20_10310	COG0811	peptide transport
CTZ20_10315	COG1475	DNA binding
CTZ20_10320	COG1192	Involved in chromosome partitioning
CTZ20_10330	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CTZ20_10345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CTZ20_10350	COG0191	fructose-bisphosphate aldolase activity
CTZ20_10370	COG0424	maF-like protein
CTZ20_10375	COG2850	peptidyl-arginine hydroxylation
CTZ20_10385	COG0640	Transcriptional regulator
CTZ20_10395	COG3619	membrane
CTZ20_10400	COG3122	Protein conserved in bacteria
CTZ20_10405	COG1132	(ABC) transporter
CTZ20_10425	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CTZ20_10430	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CTZ20_10440	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CTZ20_10440	COG0506	proline dehydrogenase activity
CTZ20_10440	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CTZ20_10445	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CTZ20_10460	COG3698	Phosphodiester glycosidase
CTZ20_10470	COG2353	YceI-like domain
CTZ20_10480	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CTZ20_10525	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CTZ20_10525	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CTZ20_10550	COG3539	Fimbrial protein
CTZ20_10555	COG3121	Chaperone
CTZ20_10585	COG0697	spore germination
CTZ20_10595	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CTZ20_10605	COG0583	DNA-binding transcription factor activity
CTZ20_10625	COG1309	transcriptional regulator
CTZ20_10645	COG1522	sequence-specific DNA binding
CTZ20_10655	COG1126	abc transporter atp-binding protein
CTZ20_10660	COG0765	amino acid transport
CTZ20_10665	COG0765	amino acid transport
CTZ20_10695	COG1464	Belongs to the NlpA lipoprotein family
CTZ20_10705	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CTZ20_10710	COG2011	ABC-type metal ion transport system permease component
CTZ20_10715	COG0012	GTP binding
CTZ20_10740	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CTZ20_10780	COG0386	Belongs to the glutathione peroxidase family
CTZ20_10790	COG0436	Aminotransferase
CTZ20_10830	COG3634	alkyl hydroperoxide reductase activity
CTZ20_10845	COG0583	DNA-binding transcription factor activity
CTZ20_10850	COG0798	PFAM Bile acid sodium symporter
CTZ20_10855	COG0640	Transcriptional regulator
CTZ20_10870	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CTZ20_10880	COG0583	DNA-binding transcription factor activity
CTZ20_10890	COG1953	Uracil, thiamine, allantoin
CTZ20_10900	COG2175	clavaminate synthase activity
CTZ20_10905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTZ20_10910	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CTZ20_10915	COG4521	taurine ABC transporter
CTZ20_10925	COG0477	Major facilitator Superfamily
CTZ20_10950	COG1271	oxidase subunit
CTZ20_10955	COG1294	oxidase, subunit
CTZ20_10965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ20_10985	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CTZ20_11005	COG3052	prosthetic group binding
CTZ20_11010	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CTZ20_11020	COG2814	Major facilitator Superfamily
CTZ20_11040	COG1346	cytolysis
CTZ20_11050	COG0583	DNA-binding transcription factor activity
CTZ20_11055	COG0625	glutathione transferase activity
CTZ20_11060	COG0625	glutathione transferase activity
CTZ20_11065	COG0583	DNA-binding transcription factor activity
CTZ20_11080	COG1045	serine acetyltransferase
CTZ20_11085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CTZ20_11090	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CTZ20_11095	COG1280	lysine exporter protein (LysE YggA)
CTZ20_11110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTZ20_11115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTZ20_11120	COG1126	abc transporter atp-binding protein
CTZ20_11125	COG0765	amino acid transport
CTZ20_11130	COG0765	amino acid transport
CTZ20_11150	COG0784	Response regulator, receiver
CTZ20_11150	COG2205	protein histidine kinase activity
CTZ20_11170	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CTZ20_11190	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_11235	COG0583	DNA-binding transcription factor activity
CTZ20_11255	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ20_11260	COG1309	transcriptional regulator
CTZ20_11265	COG1960	acyl-CoA dehydrogenase activity
CTZ20_11270	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CTZ20_11275	COG1024	Enoyl-CoA hydratase
CTZ20_11290	COG0583	DNA-binding transcription factor activity
CTZ20_11305	COG1960	acyl-CoA dehydrogenase activity
CTZ20_11315	COG2814	Major facilitator Superfamily
CTZ20_11325	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTZ20_11330	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CTZ20_11335	COG2814	Major facilitator Superfamily
CTZ20_11340	COG1960	acyl-CoA dehydrogenase activity
CTZ20_11345	COG1024	Enoyl-CoA hydratase
CTZ20_11350	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_11360	COG0183	Belongs to the thiolase family
CTZ20_11370	COG2814	Major facilitator Superfamily
CTZ20_11380	COG1024	Enoyl-CoA hydratase
CTZ20_11395	COG1960	acyl-CoA dehydrogenase activity
CTZ20_11400	COG2814	Major facilitator Superfamily
CTZ20_11405	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CTZ20_11410	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CTZ20_11425	COG3842	ATPase activity
CTZ20_11430	COG1840	ABC-type Fe3 transport system, periplasmic component
CTZ20_11440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ20_11445	COG1414	Transcriptional regulator
CTZ20_11455	COG0583	DNA-binding transcription factor activity
CTZ20_11460	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTZ20_11465	COG1012	belongs to the aldehyde dehydrogenase family
CTZ20_11475	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CTZ20_11485	COG1012	belongs to the aldehyde dehydrogenase family
CTZ20_11490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTZ20_11495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ20_11500	COG2267	carboxylic ester hydrolase activity
CTZ20_11520	COG3038	cytochrome b561
CTZ20_11525	COG0753	catalase activity
CTZ20_11565	COG2050	protein possibly involved in aromatic compounds catabolism
CTZ20_11575	COG3327	negative regulation of DNA-templated transcription, initiation
CTZ20_11580	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CTZ20_11585	COG0183	Belongs to the thiolase family
CTZ20_11590	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTZ20_11595	COG1024	Enoyl-CoA hydratase
CTZ20_11600	COG1024	Enoyl-CoA hydratase
CTZ20_11605	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTZ20_11610	COG2151	metal-sulfur cluster biosynthetic enzyme
CTZ20_11615	COG3396	Phenylacetate-CoA oxygenase
CTZ20_11620	COG3460	Phenylacetate-CoA oxygenase
CTZ20_11625	COG3396	Phenylacetate-CoA oxygenase
CTZ20_11630	COG1012	belongs to the aldehyde dehydrogenase family
CTZ20_11630	COG2030	dehydratase
CTZ20_11635	COG1760	l-serine dehydratase
CTZ20_11640	COG0531	amino acid
CTZ20_11645	COG1012	belongs to the aldehyde dehydrogenase family
CTZ20_11660	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTZ20_11670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTZ20_11690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTZ20_11705	COG0789	Transcriptional regulator
CTZ20_11730	COG1116	anion transmembrane transporter activity
CTZ20_11735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTZ20_11745	COG0864	Transcriptional regulator
CTZ20_11765	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTZ20_11770	COG0439	Biotin carboxylase
CTZ20_11785	COG1063	alcohol dehydrogenase
CTZ20_11795	COG1309	transcriptional regulator
CTZ20_11820	COG0038	chloride channel
CTZ20_11825	COG4770	biotin carboxylase activity
CTZ20_11845	COG1914	H( )-stimulated, divalent metal cation uptake system
CTZ20_11850	COG0583	DNA-binding transcription factor activity
CTZ20_11865	COG3209	COG3209 Rhs family protein
CTZ20_11870	COG3501	Rhs element vgr protein
CTZ20_11905	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTZ20_11925	COG2814	Major facilitator Superfamily
CTZ20_11940	COG1560	Kdo2-lipid A biosynthetic process
CTZ20_11950	COG5006	permease, DMT superfamily
CTZ20_11955	COG1522	sequence-specific DNA binding
CTZ20_11970	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CTZ20_12010	COG1538	Outer membrane efflux protein
CTZ20_12015	COG1137	ATPase activity
CTZ20_12020	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CTZ20_12030	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CTZ20_12035	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CTZ20_12035	COG0517	IMP dehydrogenase activity
CTZ20_12070	COG1733	regulation of RNA biosynthetic process
CTZ20_12075	COG2814	Major facilitator Superfamily
CTZ20_12115	COG1278	Cold shock
CTZ20_12120	COG1280	lysine exporter protein (LysE YggA)
CTZ20_12155	COG1570	exodeoxyribonuclease VII activity
CTZ20_12210	COG0583	DNA-binding transcription factor activity
CTZ20_12215	COG4638	Rieske (2fe-2S)
CTZ20_12220	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CTZ20_12225	COG0633	Ferredoxin
CTZ20_12225	COG0543	2 iron, 2 sulfur cluster binding
CTZ20_12230	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_12235	COG3135	benzoate transporter
CTZ20_12240	COG2814	Major facilitator Superfamily
CTZ20_12255	COG1643	Atp-dependent helicase
CTZ20_12260	COG0450	alkyl hydroperoxide reductase
CTZ20_12270	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CTZ20_12280	COG3634	alkyl hydroperoxide reductase activity
CTZ20_12300	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CTZ20_12305	COG0625	glutathione transferase activity
CTZ20_12315	COG2885	chlorophyll binding
CTZ20_12365	COG1765	OsmC-like protein
CTZ20_12385	COG0667	Aldo Keto reductase
CTZ20_12400	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CTZ20_12410	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CTZ20_12430	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CTZ20_12440	COG3038	cytochrome b561
CTZ20_12445	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CTZ20_12450	COG3316	Transposase and inactivated derivatives
CTZ20_12530	COG3316	Transposase and inactivated derivatives
CTZ20_12535	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CTZ20_12545	COG3316	Transposase and inactivated derivatives
CTZ20_12570	COG3316	Transposase and inactivated derivatives
CTZ20_12575	COG1113	amino acid transport
CTZ20_12595	COG1012	belongs to the aldehyde dehydrogenase family
CTZ20_12615	COG0531	amino acid
CTZ20_12625	COG1113	amino acid transport
CTZ20_12670	COG3209	COG3209 Rhs family protein
CTZ20_12675	COG3501	Rhs element vgr protein
CTZ20_12695	COG4269	membrane
CTZ20_12710	COG1902	pentaerythritol trinitrate reductase activity
CTZ20_12710	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTZ20_12720	COG2203	Gaf domain
CTZ20_12720	COG3706	GGDEF domain
CTZ20_12720	COG5001	Diguanylate cyclase
CTZ20_12720	COG4251	negative regulation of phosphorylation
CTZ20_12730	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CTZ20_12750	COG4172	Belongs to the ABC transporter superfamily
CTZ20_12755	COG4239	(ABC) transporter, permease
CTZ20_12760	COG4174	ABC transporter (Permease)
CTZ20_12770	COG0741	lytic transglycosylase activity
CTZ20_12770	COG0741	lytic transglycosylase activity
CTZ20_12770	COG1388	LysM domain
CTZ20_12770	COG1388	LysM domain
CTZ20_12775	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CTZ20_12815	COG0583	DNA-binding transcription factor activity
CTZ20_12820	COG1279	arginine transmembrane transporter activity
CTZ20_12840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ20_12845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ20_12850	COG0006	proline dipeptidase activity
CTZ20_12885	COG2194	sulfuric ester hydrolase activity
CTZ20_12930	COG0739	heme binding
CTZ20_13295	COG0741	lytic transglycosylase activity
CTZ20_13295	COG1196	nuclear chromosome segregation
CTZ20_13295	COG0739	heme binding
CTZ20_13350	COG4695	Portal protein
CTZ20_13445	COG0305	Participates in initiation and elongation during chromosome replication
CTZ20_13465	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CTZ20_13525	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CTZ20_13550	COG3384	dioxygenase
CTZ20_13560	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CTZ20_13565	COG2878	Part of a membrane complex involved in electron transport
CTZ20_13570	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CTZ20_13595	COG0768	penicillin binding
CTZ20_13600	COG0742	ribosomal rna small subunit methyltransferase
CTZ20_13615	COG0830	nickel cation binding
CTZ20_13625	COG0804	urea catabolic process
CTZ20_13665	COG1253	flavin adenine dinucleotide binding
CTZ20_13675	COG2851	Citrate transporter
CTZ20_13725	COG1773	rubredoxin
CTZ20_13730	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ20_13740	COG0583	DNA-binding transcription factor activity
CTZ20_13770	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CTZ20_13775	COG4181	ATPase activity
CTZ20_13820	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CTZ20_13840	COG0306	phosphate transporter
CTZ20_13850	COG3958	Transketolase
CTZ20_13855	COG3959	Transketolase, thiamine diphosphate binding domain
CTZ20_13860	COG2271	Major facilitator Superfamily
CTZ20_13865	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_13870	COG0583	DNA-binding transcription factor activity
CTZ20_13890	COG2223	nitrite transmembrane transporter activity
CTZ20_13895	COG2207	Transcriptional regulator
CTZ20_13900	COG2066	Belongs to the glutaminase family
CTZ20_13905	COG0242	peptide deformylase activity
CTZ20_13910	COG0477	Major facilitator Superfamily
CTZ20_13920	COG0028	Belongs to the TPP enzyme family
CTZ20_13935	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_13940	COG2267	carboxylic ester hydrolase activity
CTZ20_13950	COG2271	Major facilitator Superfamily
CTZ20_13955	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTZ20_13965	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_13985	COG1414	Transcriptional regulator
CTZ20_14000	COG1024	Enoyl-CoA hydratase
CTZ20_14010	COG1215	transferase activity, transferring glycosyl groups
CTZ20_14015	COG1649	PFAM Uncharacterised BCR, COG1649
CTZ20_14015	COG0726	polysaccharide deacetylase
CTZ20_14025	COG4681	YaeQ
CTZ20_14035	COG0523	cobalamin synthesis protein
CTZ20_14045	COG1607	acyl-coa hydrolase
CTZ20_14055	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTZ20_14060	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTZ20_14065	COG1309	transcriptional regulator
CTZ20_14090	COG2040	homocysteine
CTZ20_14095	COG0531	amino acid
CTZ20_14150	COG1595	DNA-templated transcription, initiation
CTZ20_14160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTZ20_14165	COG0477	Major facilitator Superfamily
CTZ20_14300	COG0592	DNA-directed DNA polymerase activity
CTZ20_14340	COG2026	Addiction module toxin, RelE StbE family
CTZ20_14490	COG3755	Protein conserved in bacteria
CTZ20_14535	COG1484	DNA-dependent DNA replication
CTZ20_14645	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CTZ20_14675	COG0405	Gamma-glutamyltransferase
CTZ20_14680	COG2814	Major facilitator Superfamily
CTZ20_14690	COG2050	protein possibly involved in aromatic compounds catabolism
CTZ20_14705	COG1090	epimerase
CTZ20_14725	COG0420	3'-5' exonuclease activity
CTZ20_14750	COG0735	belongs to the Fur family
CTZ20_14755	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CTZ20_14780	COG0121	glutamine amidotransferase
CTZ20_14795	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CTZ20_14805	COG0210	DNA helicase
CTZ20_14810	COG2885	chlorophyll binding
CTZ20_14815	COG0204	Acyl-transferase
CTZ20_14830	COG2894	cell division
CTZ20_14855	COG1280	lysine exporter protein (LysE YggA)
CTZ20_14860	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CTZ20_14860	COG1674	ftsk spoiiie
CTZ20_14865	COG0492	ferredoxin-NADP+ reductase activity
CTZ20_14870	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CTZ20_14880	COG0456	acetyltransferase
CTZ20_14940	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CTZ20_14940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CTZ20_14960	COG1012	belongs to the aldehyde dehydrogenase family
CTZ20_14980	COG0473	3-isopropylmalate dehydrogenase activity
CTZ20_14985	COG0583	DNA-binding transcription factor activity
CTZ20_15005	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTZ20_15030	COG0564	pseudouridine synthase activity
CTZ20_15040	COG0358	DNA primase activity
CTZ20_15055	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CTZ20_15085	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CTZ20_15115	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CTZ20_15125	COG0352	thiamine-phosphate diphosphorylase activity
CTZ20_15125	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CTZ20_15125	COG0351	phosphomethylpyrimidine kinase
CTZ20_15130	COG1652	LysM domain
CTZ20_15155	COG1399	metal-binding, possibly nucleic acid-binding protein
CTZ20_15160	COG3101	peptidyl-lysine hydroxylation
CTZ20_15165	COG0009	L-threonylcarbamoyladenylate synthase
CTZ20_15170	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CTZ20_15175	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CTZ20_15190	COG4106	trans-aconitate 2-methyltransferase activity
CTZ20_15205	COG2226	methyltransferase
CTZ20_15205	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTZ20_15205	COG0596	Alpha beta hydrolase
CTZ20_15210	COG1877	trehalose-phosphatase activity
CTZ20_15215	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CTZ20_15220	COG2223	nitrite transmembrane transporter activity
CTZ20_15240	COG1196	nuclear chromosome segregation
CTZ20_15250	COG0730	response to heat
CTZ20_15265	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CTZ20_15275	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CTZ20_15330	COG0489	protein tyrosine kinase activity
CTZ20_15340	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTZ20_15340	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTZ20_15370	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CTZ20_15375	COG2081	HI0933 family
CTZ20_15385	COG0668	transmembrane transport
CTZ20_15405	COG0583	DNA-binding transcription factor activity
CTZ20_15425	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTZ20_15430	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CTZ20_15460	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CTZ20_15495	COG2205	protein histidine kinase activity
CTZ20_15500	COG0745	RESPONSE REGULATOR receiver
CTZ20_15520	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CTZ20_15530	COG2205	protein histidine kinase activity
CTZ20_15600	COG4993	Dehydrogenase
CTZ20_15620	COG0384	phenazine biosynthesis protein PhzF
CTZ20_15650	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ20_15655	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CTZ20_15665	COG0583	DNA-binding transcription factor activity
CTZ20_15685	COG1473	amidohydrolase
CTZ20_15695	COG0583	DNA-binding transcription factor activity
CTZ20_15715	COG0583	DNA-binding transcription factor activity
CTZ20_15720	COG1053	succinate dehydrogenase
CTZ20_15730	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CTZ20_15735	COG2814	Major facilitator Superfamily
CTZ20_15740	COG1960	acyl-CoA dehydrogenase activity
CTZ20_15745	COG0583	DNA-binding transcription factor activity
CTZ20_15750	COG1063	alcohol dehydrogenase
CTZ20_15780	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CTZ20_15785	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CTZ20_15790	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CTZ20_15805	COG3667	copper resistance
CTZ20_15810	COG2132	Multicopper oxidase
CTZ20_15820	COG0561	phosphatase activity
CTZ20_15825	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CTZ20_15850	COG1214	PFAM Peptidase M22, glycoprotease
CTZ20_15900	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CTZ20_15910	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CTZ20_15915	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CTZ20_15920	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CTZ20_15980	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CTZ20_15990	COG1846	Transcriptional regulator
CTZ20_15995	COG1764	response to oxidative stress
CTZ20_16035	COG0037	tRNA processing
CTZ20_16045	COG0248	Ppx GppA phosphatase
CTZ20_16075	COG0072	phenylalanine-tRNA ligase activity
CTZ20_16100	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CTZ20_16115	COG1238	metal cluster binding
CTZ20_16120	COG0625	glutathione transferase activity
CTZ20_16140	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ20_16145	COG3028	Belongs to the UPF0307 family
CTZ20_16150	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTZ20_16170	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CTZ20_16175	COG0617	tRNA 3'-terminal CCA addition
CTZ20_16180	COG1555	photosystem II stabilization
CTZ20_16185	COG3956	TIGRFAM MazG family protein
CTZ20_16195	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CTZ20_16215	COG0784	Response regulator, receiver
CTZ20_16215	COG2205	protein histidine kinase activity
CTZ20_16215	COG5002	protein histidine kinase activity
CTZ20_16220	COG1024	Enoyl-CoA hydratase
CTZ20_16225	COG2084	Dehydrogenase
CTZ20_16230	COG3622	Belongs to the hyi family
CTZ20_16245	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CTZ20_16250	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CTZ20_16255	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CTZ20_16260	COG0697	spore germination
CTZ20_16270	COG2814	Major facilitator Superfamily
CTZ20_16275	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CTZ20_16285	COG0583	DNA-binding transcription factor activity
CTZ20_16295	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CTZ20_16310	COG0084	hydrolase, TatD family'
CTZ20_16325	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CTZ20_16360	COG0440	acetolactate synthase activity
CTZ20_16365	COG0028	Belongs to the TPP enzyme family
CTZ20_16390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ20_16395	COG1136	(ABC) transporter
CTZ20_16395	COG0577	efflux transmembrane transporter activity
CTZ20_16400	COG1538	Outer membrane efflux protein
CTZ20_16415	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CTZ20_16420	COG1162	GTPase activity
CTZ20_16430	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CTZ20_16450	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CTZ20_16455	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_16495	COG2986	histidine ammonia-lyase
CTZ20_16510	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ20_16520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CTZ20_16525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CTZ20_16565	COG1426	Protein conserved in bacteria
CTZ20_16600	COG0793	Belongs to the peptidase S41A family
CTZ20_16615	COG2267	carboxylic ester hydrolase activity
CTZ20_16625	COG1012	belongs to the aldehyde dehydrogenase family
CTZ20_16630	COG3265	gluconokinase activity
CTZ20_16640	COG0800	Aldolase
CTZ20_16650	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CTZ20_16655	COG0280	phosphate acetyltransferase
CTZ20_16655	COG0857	belongs to the CobB CobQ family
CTZ20_16660	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CTZ20_16660	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CTZ20_16680	COG0740	serine-type endopeptidase activity
CTZ20_16690	COG4774	siderophore transport
CTZ20_16700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CTZ20_16710	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTZ20_16710	COG2813	Specifically methylates the guanine in position
CTZ20_16810	COG0788	formyltetrahydrofolate deformylase activity
CTZ20_16825	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CTZ20_16830	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CTZ20_16835	COG4651	solute:proton antiporter activity
CTZ20_16835	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CTZ20_16855	COG0724	RNA recognition motif
CTZ20_16860	COG0210	DNA helicase
CTZ20_16885	COG1733	regulation of RNA biosynthetic process
CTZ20_16905	COG1280	lysine exporter protein (LysE YggA)
CTZ20_16910	COG1560	Kdo2-lipid A biosynthetic process
CTZ20_16920	COG1301	dicarboxylic acid transport
CTZ20_16975	COG0473	3-isopropylmalate dehydrogenase activity
CTZ20_17040	COG0583	DNA-binding transcription factor activity
CTZ20_17050	COG0625	glutathione transferase activity
CTZ20_17055	COG2378	regulation of single-species biofilm formation
CTZ20_17060	COG0546	phosphoglycolate phosphatase activity
CTZ20_17075	COG1530	ribonuclease E activity
CTZ20_17095	COG0583	DNA-binding transcription factor activity
CTZ20_17100	COG4221	oxidoreductase activity
CTZ20_17105	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CTZ20_17115	COG0534	Mate efflux family protein
CTZ20_17130	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CTZ20_17170	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CTZ20_17175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTZ20_17190	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CTZ20_17200	COG0644	oxidoreductase
CTZ20_17200	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CTZ20_17205	COG0425	Belongs to the sulfur carrier protein TusA family
CTZ20_17210	COG4535	Mg2 and Co2 transporter CorC
CTZ20_17220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTZ20_17240	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CTZ20_17245	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CTZ20_17245	COG0475	glutathione-regulated potassium exporter activity
CTZ20_17250	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CTZ20_17260	COG0484	heat shock protein binding
CTZ20_17265	COG0789	Transcriptional regulator
CTZ20_17270	COG0598	Magnesium transport protein CorA
CTZ20_17290	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CTZ20_17295	COG1074	ATP-dependent DNA helicase activity
CTZ20_17300	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CTZ20_17320	COG2226	methyltransferase
CTZ20_17335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ20_17340	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CTZ20_17355	COG2111	Na H antiporter
CTZ20_17355	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CTZ20_17360	COG1006	Multisubunit Na H antiporter MnhC subunit
CTZ20_17365	COG0651	ATP synthesis coupled electron transport
CTZ20_17375	COG2212	antiporter activity
CTZ20_17395	COG0195	Participates in both transcription termination and antitermination
CTZ20_17445	COG0237	dephospho-CoA kinase activity
CTZ20_17455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTZ20_17470	COG0497	DNA recombination
CTZ20_17480	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CTZ20_17510	COG2169	Transcriptional regulator
CTZ20_17510	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CTZ20_17515	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CTZ20_17585	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CTZ20_17600	COG0326	Molecular chaperone. Has ATPase activity
CTZ20_17615	COG2056	Na+-H+ antiporter family
CTZ20_17620	COG0596	Alpha beta hydrolase
CTZ20_17715	COG0546	phosphoglycolate phosphatase activity
CTZ20_17720	COG1716	ATPase activity
CTZ20_17765	COG0181	hydroxymethylbilane synthase activity
CTZ20_17775	COG3275	phosphorelay sensor kinase activity
CTZ20_17795	COG1538	Outer membrane efflux protein
CTZ20_17805	COG0697	spore germination
CTZ20_17830	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CTZ20_17835	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CTZ20_17840	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CTZ20_17845	COG0772	Belongs to the SEDS family
CTZ20_17870	COG4974	Belongs to the 'phage' integrase family
CTZ20_17875	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CTZ20_17885	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CTZ20_17895	COG2197	response regulator
CTZ20_17910	COG0793	Belongs to the peptidase S41A family
CTZ20_17915	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CTZ20_17920	COG0795	lipopolysaccharide-transporting ATPase activity
CTZ20_17960	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CTZ20_17960	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CTZ20_17970	COG0004	ammonium transporteR
CTZ20_17975	COG0347	Belongs to the P(II) protein family
CTZ20_17985	COG0606	chelatase, subunit chli
CTZ20_17995	COG0659	secondary active sulfate transmembrane transporter activity
CTZ20_18000	COG0589	response to stress
CTZ20_18030	COG0606	chelatase, subunit chli
CTZ20_18035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ20_18045	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTZ20_18060	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CTZ20_18075	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ20_18085	COG0477	Major facilitator Superfamily
CTZ20_18090	COG2860	membrane
CTZ20_18100	COG1253	flavin adenine dinucleotide binding
CTZ20_18120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CTZ20_18155	COG0655	NAD(P)H dehydrogenase (quinone) activity
CTZ20_18165	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CTZ20_18235	COG0758	DNA mediated transformation
CTZ20_18245	COG0697	spore germination
CTZ20_18250	COG1309	transcriptional regulator
CTZ20_18265	COG0386	Belongs to the glutathione peroxidase family
CTZ20_18330	COG1121	(ABC) transporter
CTZ20_18335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CTZ20_18340	COG1280	lysine exporter protein (LysE YggA)
CTZ20_18345	COG2837	iron assimilation
CTZ20_18350	COG0281	malic enzyme
CTZ20_18395	COG0519	Catalyzes the synthesis of GMP from XMP
CTZ20_18395	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CTZ20_18400	COG4399	Belongs to the UPF0754 family
CTZ20_18405	COG2259	Doxx family
CTZ20_18410	COG0586	Pfam SNARE associated Golgi protein
CTZ20_18425	COG1192	Involved in chromosome partitioning
CTZ20_18435	COG0271	Belongs to the BolA IbaG family
CTZ20_18475	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CTZ20_18475	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CTZ20_18475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CTZ20_18475	COG3321	synthase
CTZ20_18480	COG1960	acyl-CoA dehydrogenase activity
CTZ20_18495	COG2197	response regulator
CTZ20_18505	COG3916	Acyl-homoserine-lactone synthase
CTZ20_18510	COG0477	Major facilitator Superfamily
CTZ20_18515	COG1024	Enoyl-CoA hydratase
CTZ20_18520	COG1024	Enoyl-CoA hydratase
CTZ20_18525	COG1960	acyl-CoA dehydrogenase activity
CTZ20_18530	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTZ20_18555	COG1113	amino acid transport
CTZ20_18560	COG1113	amino acid transport
CTZ20_18565	COG0251	oxidation-reduction process
CTZ20_18580	COG1522	sequence-specific DNA binding
CTZ20_18605	COG0564	pseudouridine synthase activity
CTZ20_18680	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CTZ20_18695	COG1802	Transcriptional regulator
CTZ20_18705	COG1448	Aminotransferase
CTZ20_18710	COG0277	FAD linked oxidase domain protein
CTZ20_18720	COG2186	Transcriptional regulator
CTZ20_18730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CTZ20_18735	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CTZ20_18750	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CTZ20_18755	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CTZ20_18760	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CTZ20_18775	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CTZ20_18820	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CTZ20_18825	COG1596	polysaccharide export
CTZ20_18850	COG0728	peptidoglycan biosynthetic process
CTZ20_18855	COG3023	N-Acetylmuramoyl-L-alanine amidase
CTZ20_18915	COG0546	phosphoglycolate phosphatase activity
CTZ20_18920	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_18940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTZ20_18945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTZ20_18950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTZ20_18955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTZ20_18960	COG1116	anion transmembrane transporter activity
CTZ20_18965	COG1309	transcriptional regulator
CTZ20_18970	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CTZ20_18980	COG0196	riboflavin kinase activity
CTZ20_18985	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CTZ20_18995	COG1047	Peptidyl-prolyl cis-trans
CTZ20_19035	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CTZ20_19090	COG2951	lytic endotransglycosylase activity
CTZ20_19095	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CTZ20_19115	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CTZ20_19125	COG0671	phosphoesterase, PA-phosphatase related
CTZ20_19130	COG0861	Integral membrane protein TerC family
CTZ20_19140	COG0754	glutathionylspermidine amidase activity
CTZ20_19150	COG0402	S-adenosylhomocysteine deaminase activity
CTZ20_19165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CTZ20_19170	COG1230	cation diffusion facilitator family transporter
CTZ20_19185	COG0706	membrane insertase activity
CTZ20_19200	COG0230	Belongs to the bacterial ribosomal protein bL34 family