locus-tag	class	description
F9K57_00055	COG0772	Belongs to the SEDS family
F9K57_00060	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F9K57_00065	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F9K57_00070	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F9K57_00075	COG0494	nUDIX hydrolase
F9K57_00095	COG0697	spore germination
F9K57_00100	COG1538	Outer membrane efflux protein
F9K57_00120	COG3275	phosphorelay sensor kinase activity
F9K57_00130	COG0181	hydroxymethylbilane synthase activity
F9K57_00175	COG1716	ATPase activity
F9K57_00180	COG0546	phosphoglycolate phosphatase activity
F9K57_00280	COG2056	Na+-H+ antiporter family
F9K57_00295	COG0326	Molecular chaperone. Has ATPase activity
F9K57_00310	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
F9K57_00375	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F9K57_00380	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F9K57_00380	COG2169	Transcriptional regulator
F9K57_00410	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
F9K57_00420	COG0497	DNA recombination
F9K57_00435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F9K57_00495	COG0195	Participates in both transcription termination and antitermination
F9K57_00515	COG2212	antiporter activity
F9K57_00525	COG0651	ATP synthesis coupled electron transport
F9K57_00530	COG1006	Multisubunit Na H antiporter MnhC subunit
F9K57_00535	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F9K57_00535	COG2111	Na H antiporter
F9K57_00550	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
F9K57_00570	COG2226	methyltransferase
F9K57_00590	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
F9K57_00595	COG1074	ATP-dependent DNA helicase activity
F9K57_00600	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F9K57_00625	COG0789	Transcriptional regulator
F9K57_00645	COG0475	glutathione-regulated potassium exporter activity
F9K57_00645	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F9K57_00650	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
F9K57_00670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F9K57_00680	COG4535	Mg2 and Co2 transporter CorC
F9K57_00685	COG0425	Belongs to the sulfur carrier protein TusA family
F9K57_00695	COG0644	oxidoreductase
F9K57_00695	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
F9K57_00705	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
F9K57_00720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F9K57_00725	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
F9K57_00765	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
F9K57_00780	COG0534	Mate efflux family protein
F9K57_00790	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F9K57_00795	COG4221	oxidoreductase activity
F9K57_00800	COG0583	DNA-binding transcription factor activity
F9K57_00820	COG1530	ribonuclease E activity
F9K57_00835	COG0546	phosphoglycolate phosphatase activity
F9K57_00840	COG2378	regulation of single-species biofilm formation
F9K57_00845	COG0625	glutathione transferase activity
F9K57_00855	COG0583	DNA-binding transcription factor activity
F9K57_00920	COG0473	3-isopropylmalate dehydrogenase activity
F9K57_00975	COG1301	dicarboxylic acid transport
F9K57_00985	COG1560	Kdo2-lipid A biosynthetic process
F9K57_00990	COG1280	lysine exporter protein (LysE YggA)
F9K57_01010	COG1733	regulation of RNA biosynthetic process
F9K57_01035	COG0210	DNA helicase
F9K57_01040	COG0724	RNA recognition motif
F9K57_01060	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F9K57_01060	COG4651	solute:proton antiporter activity
F9K57_01065	COG0267	Belongs to the bacterial ribosomal protein bL33 family
F9K57_01070	COG0227	Belongs to the bacterial ribosomal protein bL28 family
F9K57_01085	COG0788	formyltetrahydrofolate deformylase activity
F9K57_01185	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F9K57_01185	COG2813	Specifically methylates the guanine in position
F9K57_01195	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F9K57_01205	COG4774	siderophore transport
F9K57_01215	COG0740	serine-type endopeptidase activity
F9K57_01235	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
F9K57_01235	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
F9K57_01240	COG0857	belongs to the CobB CobQ family
F9K57_01240	COG0280	phosphate acetyltransferase
F9K57_01245	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
F9K57_01255	COG0800	Aldolase
F9K57_01265	COG3265	gluconokinase activity
F9K57_01270	COG1012	belongs to the aldehyde dehydrogenase family
F9K57_01280	COG2267	carboxylic ester hydrolase activity
F9K57_01295	COG0793	Belongs to the peptidase S41A family
F9K57_01330	COG1426	Protein conserved in bacteria
F9K57_01370	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F9K57_01380	COG1162	GTPase activity
F9K57_01385	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
F9K57_01400	COG1538	Outer membrane efflux protein
F9K57_01405	COG0577	efflux transmembrane transporter activity
F9K57_01405	COG1136	(ABC) transporter
F9K57_01410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9K57_01435	COG0028	Belongs to the TPP enzyme family
F9K57_01440	COG0440	acetolactate synthase activity
F9K57_01475	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
F9K57_01490	COG0084	hydrolase, TatD family'
F9K57_01505	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
F9K57_01515	COG0583	DNA-binding transcription factor activity
F9K57_01525	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F9K57_01530	COG2814	Major facilitator Superfamily
F9K57_01545	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
F9K57_01550	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
F9K57_01555	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
F9K57_01570	COG3622	Belongs to the hyi family
F9K57_01575	COG2084	Dehydrogenase
F9K57_01580	COG1024	Enoyl-CoA hydratase
F9K57_01585	COG0784	Response regulator, receiver
F9K57_01585	COG2205	protein histidine kinase activity
F9K57_01585	COG5002	protein histidine kinase activity
F9K57_01605	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F9K57_01615	COG3956	TIGRFAM MazG family protein
F9K57_01620	COG1555	photosystem II stabilization
F9K57_01625	COG0617	tRNA 3'-terminal CCA addition
F9K57_01630	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F9K57_01650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F9K57_01655	COG3028	Belongs to the UPF0307 family
F9K57_01660	COG0318	PFAM AMP-dependent synthetase and ligase
F9K57_01675	COG0625	glutathione transferase activity
F9K57_01680	COG1238	metal cluster binding
F9K57_01695	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
F9K57_01715	COG0072	phenylalanine-tRNA ligase activity
F9K57_01745	COG0248	Ppx GppA phosphatase
F9K57_01755	COG0037	tRNA processing
F9K57_01795	COG1764	response to oxidative stress
F9K57_01800	COG1846	Transcriptional regulator
F9K57_01810	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F9K57_01870	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
F9K57_01875	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
F9K57_01880	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
F9K57_01940	COG1214	PFAM Peptidase M22, glycoprotease
F9K57_01965	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F9K57_01970	COG0561	phosphatase activity
F9K57_01980	COG2132	Multicopper oxidase
F9K57_01985	COG3667	copper resistance
F9K57_02000	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F9K57_02005	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
F9K57_02010	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
F9K57_02040	COG1063	alcohol dehydrogenase
F9K57_02045	COG0583	DNA-binding transcription factor activity
F9K57_02050	COG1960	acyl-CoA dehydrogenase activity
F9K57_02055	COG2814	Major facilitator Superfamily
F9K57_02060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F9K57_02065	COG1309	transcriptional regulator
F9K57_02080	COG1053	succinate dehydrogenase
F9K57_02085	COG0583	DNA-binding transcription factor activity
F9K57_02105	COG0583	DNA-binding transcription factor activity
F9K57_02135	COG1473	amidohydrolase
F9K57_02155	COG0583	DNA-binding transcription factor activity
F9K57_02165	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
F9K57_02170	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F9K57_02205	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F9K57_02225	COG0745	RESPONSE REGULATOR receiver
F9K57_02230	COG2205	protein histidine kinase activity
F9K57_02265	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
F9K57_02295	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F9K57_02300	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F9K57_02320	COG0583	DNA-binding transcription factor activity
F9K57_02340	COG0668	transmembrane transport
F9K57_02350	COG2081	HI0933 family
F9K57_02355	COG2515	1-aminocyclopropane-1-carboxylate deaminase
F9K57_02385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F9K57_02385	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F9K57_02395	COG0489	protein tyrosine kinase activity
F9K57_02455	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F9K57_02465	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F9K57_02480	COG0730	response to heat
F9K57_02490	COG1196	nuclear chromosome segregation
F9K57_02510	COG2223	nitrite transmembrane transporter activity
F9K57_02515	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
F9K57_02520	COG1877	trehalose-phosphatase activity
F9K57_02525	COG2226	methyltransferase
F9K57_02525	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F9K57_02525	COG0596	Alpha beta hydrolase
F9K57_02540	COG4106	trans-aconitate 2-methyltransferase activity
F9K57_02555	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
F9K57_02560	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
F9K57_02565	COG0009	L-threonylcarbamoyladenylate synthase
F9K57_02570	COG3101	peptidyl-lysine hydroxylation
F9K57_02575	COG1399	metal-binding, possibly nucleic acid-binding protein
F9K57_02600	COG1652	LysM domain
F9K57_02605	COG0352	thiamine-phosphate diphosphorylase activity
F9K57_02605	COG0351	phosphomethylpyrimidine kinase
F9K57_02605	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
F9K57_02615	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F9K57_02645	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F9K57_02675	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
F9K57_02690	COG0358	DNA primase activity
F9K57_02700	COG0564	pseudouridine synthase activity
F9K57_02725	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F9K57_02745	COG0583	DNA-binding transcription factor activity
F9K57_02750	COG0473	3-isopropylmalate dehydrogenase activity
F9K57_02770	COG1012	belongs to the aldehyde dehydrogenase family
F9K57_02790	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
F9K57_02790	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F9K57_02850	COG0456	acetyltransferase
F9K57_02860	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
F9K57_02865	COG0492	ferredoxin-NADP+ reductase activity
F9K57_02870	COG1674	ftsk spoiiie
F9K57_02870	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F9K57_02875	COG1280	lysine exporter protein (LysE YggA)
F9K57_02895	COG2894	cell division
F9K57_02910	COG0204	Acyl-transferase
F9K57_02915	COG2885	chlorophyll binding
F9K57_02920	COG0210	DNA helicase
F9K57_02945	COG0121	glutamine amidotransferase
F9K57_02970	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F9K57_02975	COG0735	belongs to the Fur family
F9K57_03000	COG0420	3'-5' exonuclease activity
F9K57_03020	COG1090	epimerase
F9K57_03035	COG2050	protein possibly involved in aromatic compounds catabolism
F9K57_03045	COG2814	Major facilitator Superfamily
F9K57_03290	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F9K57_03300	COG0582	viral genome integration into host DNA
F9K57_03355	COG0084	hydrolase, TatD family'
F9K57_03375	COG0477	Major facilitator Superfamily
F9K57_03380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F9K57_03390	COG1595	DNA-templated transcription, initiation
F9K57_03445	COG0531	amino acid
F9K57_03450	COG2040	homocysteine
F9K57_03475	COG1309	transcriptional regulator
F9K57_03480	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F9K57_03485	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F9K57_03495	COG1607	acyl-coa hydrolase
F9K57_03505	COG0523	cobalamin synthesis protein
F9K57_03515	COG4681	YaeQ
F9K57_03525	COG0726	polysaccharide deacetylase
F9K57_03525	COG1649	PFAM Uncharacterised BCR, COG1649
F9K57_03530	COG1215	transferase activity, transferring glycosyl groups
F9K57_03540	COG1024	Enoyl-CoA hydratase
F9K57_03555	COG1414	Transcriptional regulator
F9K57_03575	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_03585	COG0446	pyridine nucleotide-disulphide oxidoreductase
F9K57_03590	COG2271	Major facilitator Superfamily
F9K57_03600	COG2267	carboxylic ester hydrolase activity
F9K57_03605	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_03620	COG0028	Belongs to the TPP enzyme family
F9K57_03630	COG0477	Major facilitator Superfamily
F9K57_03635	COG0242	peptide deformylase activity
F9K57_03640	COG2066	Belongs to the glutaminase family
F9K57_03645	COG2207	Transcriptional regulator
F9K57_03650	COG2223	nitrite transmembrane transporter activity
F9K57_03670	COG0583	DNA-binding transcription factor activity
F9K57_03675	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_03680	COG2271	Major facilitator Superfamily
F9K57_03685	COG3959	Transketolase, thiamine diphosphate binding domain
F9K57_03690	COG3958	Transketolase
F9K57_03720	COG0306	phosphate transporter
F9K57_03740	COG1262	PFAM Formylglycine-generating sulfatase enzyme
F9K57_03785	COG4181	ATPase activity
F9K57_03790	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
F9K57_03820	COG0583	DNA-binding transcription factor activity
F9K57_03830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F9K57_03835	COG1773	rubredoxin
F9K57_03885	COG2851	Citrate transporter
F9K57_03895	COG1253	flavin adenine dinucleotide binding
F9K57_03935	COG0804	urea catabolic process
F9K57_03945	COG0830	nickel cation binding
F9K57_03960	COG0742	ribosomal rna small subunit methyltransferase
F9K57_03965	COG0768	penicillin binding
F9K57_03990	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
F9K57_03995	COG2878	Part of a membrane complex involved in electron transport
F9K57_04000	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F9K57_04010	COG3384	dioxygenase
F9K57_04030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
F9K57_04190	COG5410	chromosome segregation
F9K57_04300	COG0739	heme binding
F9K57_04300	COG0741	lytic transglycosylase activity
F9K57_04300	COG1196	nuclear chromosome segregation
F9K57_04400	COG0006	proline dipeptidase activity
F9K57_04405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F9K57_04410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F9K57_04430	COG1279	arginine transmembrane transporter activity
F9K57_04435	COG0583	DNA-binding transcription factor activity
F9K57_04475	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F9K57_04480	COG0741	lytic transglycosylase activity
F9K57_04480	COG1388	LysM domain
F9K57_04480	COG0741	lytic transglycosylase activity
F9K57_04480	COG1388	LysM domain
F9K57_04490	COG4174	ABC transporter (Permease)
F9K57_04495	COG4239	(ABC) transporter, permease
F9K57_04500	COG4172	Belongs to the ABC transporter superfamily
F9K57_04525	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F9K57_04535	COG3706	GGDEF domain
F9K57_04535	COG4251	negative regulation of phosphorylation
F9K57_04535	COG2203	Gaf domain
F9K57_04535	COG5001	Diguanylate cyclase
F9K57_04545	COG1902	pentaerythritol trinitrate reductase activity
F9K57_04545	COG0446	pyridine nucleotide-disulphide oxidoreductase
F9K57_04570	COG3501	Rhs element vgr protein
F9K57_04615	COG1113	amino acid transport
F9K57_04645	COG1012	belongs to the aldehyde dehydrogenase family
F9K57_04665	COG1113	amino acid transport
F9K57_04670	COG2831	hemolysin activation secretion protein
F9K57_04710	COG0697	spore germination
F9K57_04715	COG2721	sulfolactate sulfo-lyase activity
F9K57_04720	COG2271	Major facilitator Superfamily
F9K57_04725	COG4948	Mandelate Racemase Muconate Lactonizing
F9K57_04735	COG1012	belongs to the aldehyde dehydrogenase family
F9K57_04740	COG2186	Transcriptional regulator
F9K57_04765	COG1960	acyl-CoA dehydrogenase activity
F9K57_04775	COG1012	belongs to the aldehyde dehydrogenase family
F9K57_04780	COG1024	Enoyl-CoA hydratase
F9K57_04785	COG2814	Major facilitator Superfamily
F9K57_04800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F9K57_04845	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
F9K57_04850	COG2072	flavoprotein involved in K transport
F9K57_04855	COG0300	oxidoreductase activity
F9K57_04865	COG1309	transcriptional regulator
F9K57_04870	COG1741	Belongs to the pirin family
F9K57_04885	COG2072	flavoprotein involved in K transport
F9K57_04895	COG2252	PERMEase
F9K57_04900	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
F9K57_04905	COG3038	cytochrome b561
F9K57_04915	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
F9K57_04935	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F9K57_04945	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
F9K57_04960	COG0667	Aldo Keto reductase
F9K57_04970	COG1765	OsmC-like protein
F9K57_05020	COG2885	chlorophyll binding
F9K57_05030	COG0625	glutathione transferase activity
F9K57_05035	COG0220	tRNA (guanine-N7-)-methyltransferase activity
F9K57_05055	COG3634	alkyl hydroperoxide reductase activity
F9K57_05065	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
F9K57_05075	COG0450	alkyl hydroperoxide reductase
F9K57_05080	COG1643	Atp-dependent helicase
F9K57_05095	COG2814	Major facilitator Superfamily
F9K57_05100	COG3135	benzoate transporter
F9K57_05105	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_05110	COG0543	2 iron, 2 sulfur cluster binding
F9K57_05110	COG0633	Ferredoxin
F9K57_05115	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
F9K57_05120	COG4638	Rieske (2fe-2S)
F9K57_05125	COG0583	DNA-binding transcription factor activity
F9K57_05215	COG1280	lysine exporter protein (LysE YggA)
F9K57_05220	COG1278	Cold shock
F9K57_05260	COG2814	Major facilitator Superfamily
F9K57_05265	COG1733	regulation of RNA biosynthetic process
F9K57_05350	COG5410	chromosome segregation
F9K57_05475	COG0739	heme binding
F9K57_05550	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F9K57_05550	COG0517	IMP dehydrogenase activity
F9K57_05555	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
F9K57_05565	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
F9K57_05570	COG1137	ATPase activity
F9K57_05575	COG1538	Outer membrane efflux protein
F9K57_05615	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
F9K57_05630	COG1522	sequence-specific DNA binding
F9K57_05635	COG5006	permease, DMT superfamily
F9K57_05690	COG1250	3-hydroxyacyl-CoA dehydrogenase
F9K57_05720	COG3501	Rhs element vgr protein
F9K57_05765	COG0583	DNA-binding transcription factor activity
F9K57_05770	COG1914	H( )-stimulated, divalent metal cation uptake system
F9K57_05790	COG4770	biotin carboxylase activity
F9K57_05800	COG2831	hemolysin activation secretion protein
F9K57_05805	COG3210	domain, Protein
F9K57_05830	COG1309	transcriptional regulator
F9K57_05840	COG1063	alcohol dehydrogenase
F9K57_05855	COG0439	Biotin carboxylase
F9K57_05860	COG2249	NAD(P)H dehydrogenase (quinone) activity
F9K57_05865	COG1733	regulation of RNA biosynthetic process
F9K57_05880	COG0864	Transcriptional regulator
F9K57_05890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F9K57_05895	COG1116	anion transmembrane transporter activity
F9K57_05965	COG2885	chlorophyll binding
F9K57_05965	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
F9K57_06005	COG0583	DNA-binding transcription factor activity
F9K57_06015	COG0590	tRNA wobble adenosine to inosine editing
F9K57_06020	COG2807	transmembrane transport
F9K57_06035	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F9K57_06045	COG0789	Transcriptional regulator
F9K57_06060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F9K57_06105	COG1012	belongs to the aldehyde dehydrogenase family
F9K57_06110	COG0531	amino acid
F9K57_06115	COG1760	l-serine dehydratase
F9K57_06120	COG1012	belongs to the aldehyde dehydrogenase family
F9K57_06120	COG2030	dehydratase
F9K57_06125	COG3396	Phenylacetate-CoA oxygenase
F9K57_06130	COG3460	Phenylacetate-CoA oxygenase
F9K57_06135	COG3396	Phenylacetate-CoA oxygenase
F9K57_06140	COG2151	metal-sulfur cluster biosynthetic enzyme
F9K57_06145	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F9K57_06150	COG1024	Enoyl-CoA hydratase
F9K57_06155	COG1024	Enoyl-CoA hydratase
F9K57_06160	COG1250	3-hydroxyacyl-CoA dehydrogenase
F9K57_06165	COG0183	Belongs to the thiolase family
F9K57_06170	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
F9K57_06175	COG3327	negative regulation of DNA-templated transcription, initiation
F9K57_06185	COG2050	protein possibly involved in aromatic compounds catabolism
F9K57_06195	COG0406	alpha-ribazole phosphatase activity
F9K57_06250	COG1278	Cold shock
F9K57_06260	COG2207	Transcriptional regulator
F9K57_06280	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F9K57_06285	COG2271	Major facilitator Superfamily
F9K57_06290	COG0753	catalase activity
F9K57_06295	COG3038	cytochrome b561
F9K57_06315	COG2267	carboxylic ester hydrolase activity
F9K57_06320	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F9K57_06325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F9K57_06330	COG1012	belongs to the aldehyde dehydrogenase family
F9K57_06340	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
F9K57_06350	COG1012	belongs to the aldehyde dehydrogenase family
F9K57_06355	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F9K57_06360	COG0583	DNA-binding transcription factor activity
F9K57_06370	COG1414	Transcriptional regulator
F9K57_06375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F9K57_06385	COG1840	ABC-type Fe3 transport system, periplasmic component
F9K57_06390	COG3842	ATPase activity
F9K57_06405	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
F9K57_06410	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F9K57_06415	COG2814	Major facilitator Superfamily
F9K57_06420	COG1960	acyl-CoA dehydrogenase activity
F9K57_06435	COG1024	Enoyl-CoA hydratase
F9K57_06445	COG2814	Major facilitator Superfamily
F9K57_06455	COG0183	Belongs to the thiolase family
F9K57_06460	COG1250	3-hydroxyacyl-CoA dehydrogenase
F9K57_06465	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_06470	COG1024	Enoyl-CoA hydratase
F9K57_06475	COG1960	acyl-CoA dehydrogenase activity
F9K57_06480	COG2814	Major facilitator Superfamily
F9K57_06485	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
F9K57_06490	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F9K57_06500	COG2814	Major facilitator Superfamily
F9K57_06510	COG1960	acyl-CoA dehydrogenase activity
F9K57_06525	COG0583	DNA-binding transcription factor activity
F9K57_06540	COG1024	Enoyl-CoA hydratase
F9K57_06545	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F9K57_06550	COG1960	acyl-CoA dehydrogenase activity
F9K57_06555	COG1309	transcriptional regulator
F9K57_06560	COG0318	PFAM AMP-dependent synthetase and ligase
F9K57_06625	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_06645	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
F9K57_06685	COG0765	amino acid transport
F9K57_06690	COG0765	amino acid transport
F9K57_06695	COG1126	abc transporter atp-binding protein
F9K57_06705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F9K57_06720	COG1280	lysine exporter protein (LysE YggA)
F9K57_06725	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F9K57_06730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F9K57_06735	COG1045	serine acetyltransferase
F9K57_06750	COG0583	DNA-binding transcription factor activity
F9K57_06755	COG0625	glutathione transferase activity
F9K57_06760	COG0625	glutathione transferase activity
F9K57_06765	COG0583	DNA-binding transcription factor activity
F9K57_06775	COG1346	cytolysis
F9K57_06795	COG2814	Major facilitator Superfamily
F9K57_06805	COG0583	DNA-binding transcription factor activity
F9K57_06815	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
F9K57_06820	COG3052	prosthetic group binding
F9K57_06840	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
F9K57_06860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F9K57_06870	COG1294	oxidase, subunit
F9K57_06875	COG1271	oxidase subunit
F9K57_06900	COG0477	Major facilitator Superfamily
F9K57_06910	COG4521	taurine ABC transporter
F9K57_06915	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
F9K57_06920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F9K57_06925	COG2175	clavaminate synthase activity
F9K57_06935	COG1953	Uracil, thiamine, allantoin
F9K57_06945	COG0583	DNA-binding transcription factor activity
F9K57_06955	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
F9K57_06970	COG0640	Transcriptional regulator
F9K57_06975	COG0798	PFAM Bile acid sodium symporter
F9K57_06980	COG0583	DNA-binding transcription factor activity
F9K57_06995	COG3634	alkyl hydroperoxide reductase activity
F9K57_07030	COG1301	dicarboxylic acid transport
F9K57_07035	COG0436	Aminotransferase
F9K57_07085	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
F9K57_07110	COG0012	GTP binding
F9K57_07115	COG2011	ABC-type metal ion transport system permease component
F9K57_07120	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F9K57_07130	COG1464	Belongs to the NlpA lipoprotein family
F9K57_07160	COG0765	amino acid transport
F9K57_07165	COG0765	amino acid transport
F9K57_07170	COG1126	abc transporter atp-binding protein
F9K57_07180	COG1522	sequence-specific DNA binding
F9K57_07195	COG1309	transcriptional regulator
F9K57_07265	COG0583	DNA-binding transcription factor activity
F9K57_07275	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
F9K57_07285	COG0697	spore germination
F9K57_07310	COG3121	Chaperone
F9K57_07315	COG3539	Fimbrial protein
F9K57_07340	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
F9K57_07340	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F9K57_07385	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F9K57_07395	COG2353	YceI-like domain
F9K57_07405	COG3698	Phosphodiester glycosidase
F9K57_07420	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
F9K57_07425	COG0506	proline dehydrogenase activity
F9K57_07425	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F9K57_07425	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F9K57_07435	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F9K57_07440	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
F9K57_07460	COG1132	(ABC) transporter
F9K57_07465	COG3122	Protein conserved in bacteria
F9K57_07470	COG3619	membrane
F9K57_07480	COG0640	Transcriptional regulator
F9K57_07490	COG2850	peptidyl-arginine hydroxylation
F9K57_07495	COG0424	maF-like protein
F9K57_07515	COG0191	fructose-bisphosphate aldolase activity
F9K57_07520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F9K57_07535	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
F9K57_07545	COG1192	Involved in chromosome partitioning
F9K57_07550	COG1475	DNA binding
F9K57_07555	COG0811	peptide transport
F9K57_07565	COG1132	(ABC) transporter
F9K57_07570	COG1663	tetraacyldisaccharide 4'-kinase activity
F9K57_07590	COG0084	hydrolase, TatD family'
F9K57_07605	COG2165	general secretion pathway protein
F9K57_07635	COG0590	tRNA wobble adenosine to inosine editing
F9K57_07655	COG0776	regulation of translation
F9K57_07685	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
F9K57_07690	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
F9K57_07740	COG0339	signal peptide processing
F9K57_07750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F9K57_07785	COG0702	epimerase
F9K57_07790	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F9K57_07810	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F9K57_07840	COG0316	Belongs to the HesB IscA family
F9K57_07845	COG0822	iron-sulfur transferase activity
F9K57_07870	COG0776	regulation of translation
F9K57_07875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F9K57_07880	COG2207	Transcriptional regulator
F9K57_07885	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F9K57_07890	COG1960	acyl-CoA dehydrogenase activity
F9K57_07895	COG1960	acyl-CoA dehydrogenase activity
F9K57_07910	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F9K57_07930	COG4264	IucA IucC family
F9K57_07935	COG4264	IucA IucC family
F9K57_07945	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F9K57_07995	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
F9K57_08000	COG0406	alpha-ribazole phosphatase activity
F9K57_08015	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F9K57_08020	COG0730	response to heat
F9K57_08040	COG4773	Receptor
F9K57_08045	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F9K57_08060	COG1131	(ABC) transporter
F9K57_08065	COG0842	Transport permease protein
F9K57_08070	COG0842	Transport permease protein
F9K57_08125	COG2226	methyltransferase
F9K57_08150	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
F9K57_08185	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F9K57_08195	COG0133	tryptophan synthase activity
F9K57_08210	COG3706	GGDEF domain
F9K57_08225	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
F9K57_08230	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
F9K57_08235	COG0022	dehydrogenase e1 component
F9K57_08240	COG0508	dehydrogenase complex catalyzes the overall conversion of
F9K57_08245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F9K57_08255	COG1063	alcohol dehydrogenase
F9K57_08260	COG3781	membrane
F9K57_08280	COG0730	response to heat
F9K57_08295	COG2207	Transcriptional regulator
F9K57_08295	COG3708	Transcriptional regulator
F9K57_08300	COG1733	regulation of RNA biosynthetic process
F9K57_08305	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
F9K57_08330	COG4521	taurine ABC transporter
F9K57_08335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F9K57_08355	COG0477	Major facilitator Superfamily
F9K57_08365	COG1027	Aspartate ammonia-lyase
F9K57_08380	COG0583	DNA-binding transcription factor activity
F9K57_08385	COG0583	DNA-binding transcription factor activity
F9K57_08390	COG0183	Belongs to the thiolase family
F9K57_08410	COG0583	DNA-binding transcription factor activity
F9K57_08420	COG2610	gluconate transmembrane transporter activity
F9K57_08425	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_08430	COG2207	Transcriptional regulator
F9K57_08440	COG0412	Dienelactone hydrolase
F9K57_08445	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_08455	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F9K57_08470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F9K57_08470	COG0543	2 iron, 2 sulfur cluster binding
F9K57_08475	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
F9K57_08480	COG4638	Rieske (2fe-2S)
F9K57_08490	COG0725	ABC transporter, periplasmic molybdate-binding protein
F9K57_08495	COG4149	molybdate abc transporter
F9K57_08500	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
F9K57_08505	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_08510	COG3433	isochorismatase activity
F9K57_08510	COG1535	isochorismatase
F9K57_08575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F9K57_08590	COG0753	catalase activity
F9K57_08600	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
F9K57_08630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F9K57_08635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9K57_08640	COG0745	RESPONSE REGULATOR receiver
F9K57_08645	COG2205	protein histidine kinase activity
F9K57_08655	COG2207	Transcriptional regulator
F9K57_08675	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_08690	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
F9K57_08730	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
F9K57_08780	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F9K57_08800	COG1120	ATPase activity
F9K57_08815	COG1064	alcohol dehydrogenase
F9K57_08820	COG2207	Transcriptional regulator
F9K57_08825	COG2084	Dehydrogenase
F9K57_08835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F9K57_08840	COG0583	DNA-binding transcription factor activity
F9K57_08850	COG0129	dihydroxy-acid dehydratase activity
F9K57_08855	COG1012	belongs to the aldehyde dehydrogenase family
F9K57_08870	COG1566	PFAM secretion protein HlyD family protein
F9K57_08885	COG0583	DNA-binding transcription factor activity
F9K57_08950	COG0318	PFAM AMP-dependent synthetase and ligase
F9K57_08960	COG1960	acyl-CoA dehydrogenase activity
F9K57_08970	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_08980	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_08985	COG0583	DNA-binding transcription factor activity
F9K57_08990	COG1309	transcriptional regulator
F9K57_09035	COG1902	pentaerythritol trinitrate reductase activity
F9K57_09035	COG0446	pyridine nucleotide-disulphide oxidoreductase
F9K57_09050	COG1012	belongs to the aldehyde dehydrogenase family
F9K57_09070	COG2186	Transcriptional regulator
F9K57_09080	COG0583	DNA-binding transcription factor activity
F9K57_09085	COG4948	Mandelate Racemase Muconate Lactonizing
F9K57_09090	COG4829	muconolactone delta-isomerase
F9K57_09100	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
F9K57_09105	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F9K57_09110	COG0183	Belongs to the thiolase family
F9K57_09115	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F9K57_09125	COG1012	belongs to the aldehyde dehydrogenase family
F9K57_09145	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F9K57_09155	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_09165	COG4638	Rieske (2fe-2S)
F9K57_09185	COG0154	amidase activity
F9K57_09195	COG2814	Major facilitator Superfamily
F9K57_09220	COG1960	acyl-CoA dehydrogenase activity
F9K57_09225	COG0583	DNA-binding transcription factor activity
F9K57_09230	COG1414	Transcriptional regulator
F9K57_09245	COG2391	methyltransferase activity
F9K57_09255	COG4993	Dehydrogenase
F9K57_09260	COG3659	wide pore channel activity
F9K57_09265	COG3420	alginic acid biosynthetic process
F9K57_09270	COG0710	3-dehydroquinate dehydratase activity
F9K57_09275	COG3485	protocatechuate 3,4-dioxygenase
F9K57_09280	COG3485	protocatechuate 3,4-dioxygenase
F9K57_09285	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F9K57_09290	COG2271	Major facilitator Superfamily
F9K57_09295	COG0596	Alpha beta hydrolase
F9K57_09300	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F9K57_09305	COG0183	Belongs to the thiolase family
F9K57_09315	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
F9K57_09325	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
F9K57_09330	COG2323	membrane
F9K57_09375	COG1902	pentaerythritol trinitrate reductase activity
F9K57_09375	COG0446	pyridine nucleotide-disulphide oxidoreductase
F9K57_09390	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F9K57_09400	COG0542	response to heat
F9K57_09405	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
F9K57_09435	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F9K57_09440	COG0569	domain protein
F9K57_09445	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F9K57_09460	COG4774	siderophore transport
F9K57_09465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F9K57_09475	COG1585	Membrane protein implicated in regulation of membrane protease activity
F9K57_09490	COG1294	oxidase, subunit
F9K57_09495	COG4890	Cyd operon protein YbgT
F9K57_09505	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
F9K57_09515	COG0552	protein localization to endoplasmic reticulum
F9K57_09540	COG0517	IMP dehydrogenase activity
F9K57_09540	COG0516	GMP reductase activity
F9K57_09545	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F9K57_09550	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
F9K57_09560	COG0583	DNA-binding transcription factor activity
F9K57_09565	COG0024	Methionine aminopeptidase
F9K57_09595	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
F9K57_09595	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F9K57_09605	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F9K57_09605	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
F9K57_09605	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F9K57_09625	COG3300	MHYT domain
F9K57_09625	COG5001	Diguanylate cyclase
F9K57_09645	COG0659	secondary active sulfate transmembrane transporter activity
F9K57_09660	COG1113	amino acid transport
F9K57_09670	COG1522	sequence-specific DNA binding
F9K57_09695	COG1011	Hydrolase
F9K57_09700	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
F9K57_09710	COG2137	regulation of response to DNA damage stimulus
F9K57_09725	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F9K57_09745	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F9K57_09760	COG0575	Belongs to the CDS family
F9K57_09765	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
F9K57_09790	COG3852	Histidine kinase
F9K57_09795	COG2204	response regulator
F9K57_09860	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
F9K57_09885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F9K57_09895	COG0303	'Molybdopterin
F9K57_09900	COG0315	cyclic pyranopterin monophosphate synthase activity
F9K57_09900	COG0521	Mo-molybdopterin cofactor biosynthetic process
F9K57_09915	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
F9K57_09920	COG0243	molybdopterin cofactor binding
F9K57_09930	COG0243	molybdopterin cofactor binding
F9K57_09935	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F9K57_09940	COG2146	nitrite reductase [NAD(P)H] activity
F9K57_09940	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F9K57_09950	COG0745	RESPONSE REGULATOR receiver
F9K57_09955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F9K57_09955	COG1116	anion transmembrane transporter activity
F9K57_09975	COG0511	ligase activity, forming carbon-carbon bonds
F9K57_10010	COG0069	glutamate synthase activity
F9K57_10050	COG1454	alcohol dehydrogenase
F9K57_10055	COG0824	Thioesterase
F9K57_10065	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
F9K57_10095	COG0183	Belongs to the thiolase family
F9K57_10105	COG0583	DNA-binding transcription factor activity
F9K57_10120	COG1522	sequence-specific DNA binding
F9K57_10125	COG3135	benzoate transporter
F9K57_10135	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
F9K57_10150	COG0589	response to stress
F9K57_10155	COG0488	(ABC) transporter
F9K57_10175	COG4773	Receptor
F9K57_10205	COG0668	transmembrane transport
F9K57_10215	COG1309	transcriptional regulator
F9K57_10235	COG1605	Chorismate mutase
F9K57_10275	COG0308	aminopeptidase N
F9K57_10300	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F9K57_10305	COG1454	alcohol dehydrogenase
F9K57_10325	COG0531	amino acid
F9K57_10330	COG4303	Ethanolamine ammonia lyase large subunit
F9K57_10335	COG4302	ethanolamine ammonia-lyase activity
F9K57_10340	COG0519	Catalyzes the synthesis of GMP from XMP
F9K57_10340	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F9K57_10370	COG0697	spore germination
F9K57_10375	COG1923	regulation of RNA biosynthetic process
F9K57_10385	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
F9K57_10390	COG0802	atpase or kinase
F9K57_10425	COG0583	DNA-binding transcription factor activity
F9K57_10440	COG2814	Major facilitator Superfamily
F9K57_10445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F9K57_10475	COG0729	surface antigen
F9K57_10495	COG0174	glutamine synthetase
F9K57_10500	COG0745	RESPONSE REGULATOR receiver
F9K57_10505	COG2205	protein histidine kinase activity
F9K57_10510	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
F9K57_10515	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
F9K57_10520	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
F9K57_10545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F9K57_10550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F9K57_10555	COG1960	acyl-CoA dehydrogenase activity
F9K57_10570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F9K57_10575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F9K57_10595	COG0583	DNA-binding transcription factor activity
F9K57_10615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F9K57_10625	COG3658	cytochrome
F9K57_10630	COG1215	transferase activity, transferring glycosyl groups
F9K57_10635	COG0726	polysaccharide deacetylase
F9K57_10635	COG1649	PFAM Uncharacterised BCR, COG1649
F9K57_10660	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F9K57_10665	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F9K57_10675	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
F9K57_10700	COG0305	Participates in initiation and elongation during chromosome replication
F9K57_10705	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F9K57_10715	COG1305	Transglutaminase-like
F9K57_10725	COG2308	Evidence 4 Homologs of previously reported genes of
F9K57_10755	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
F9K57_10760	COG0138	bifunctional purine biosynthesis protein purh
F9K57_10765	COG0151	Belongs to the GarS family
F9K57_10770	COG1464	Belongs to the NlpA lipoprotein family
F9K57_10775	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F9K57_10780	COG2011	ABC-type metal ion transport system permease component
F9K57_10785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F9K57_10795	COG1301	dicarboxylic acid transport
F9K57_10825	COG1794	racemase activity, acting on amino acids and derivatives
F9K57_10850	COG0642	Histidine kinase
F9K57_10855	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F9K57_10865	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F9K57_10905	COG2351	hydroxyisourate hydrolase activity
F9K57_10915	COG3008	intermembrane lipid transfer
F9K57_10915	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F9K57_10920	COG2995	paraquat-inducible protein a
F9K57_11005	COG2186	Transcriptional regulator
F9K57_11020	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_11030	COG0583	DNA-binding transcription factor activity
F9K57_11045	COG3243	poly(R)-hydroxyalkanoic acid synthase
F9K57_11070	COG3111	PFAM Bacterial OB fold (BOF) protein
F9K57_11140	COG0515	serine threonine protein kinase
F9K57_11140	COG2815	serine threonine protein kinase
F9K57_11165	COG0828	Belongs to the bacterial ribosomal protein bS21 family
F9K57_11170	COG1610	YqeY-like protein
F9K57_11175	COG4783	chaperone-mediated protein folding
F9K57_11200	COG1286	toxin biosynthetic process
F9K57_11230	COG0778	Nitroreductase
F9K57_11240	COG0513	Belongs to the DEAD box helicase family
F9K57_11260	COG2363	Small membrane protein
F9K57_11290	COG1234	tRNA 3'-trailer cleavage
F9K57_11295	COG2195	Cleaves the N-terminal amino acid of tripeptides
F9K57_11305	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
F9K57_11315	COG2819	hydrolase of the alpha beta superfamily
F9K57_11320	COG1960	acyl-CoA dehydrogenase activity
F9K57_11325	COG1301	dicarboxylic acid transport
F9K57_11340	COG3139	Protein of unknown function (DUF1315)
F9K57_11345	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
F9K57_11350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F9K57_11360	COG0494	nUDIX hydrolase
F9K57_11370	COG0642	Histidine kinase
F9K57_11375	COG0745	RESPONSE REGULATOR receiver
F9K57_11395	COG1720	tRNA m6t6A37 methyltransferase activity
F9K57_11410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F9K57_11420	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F9K57_11430	COG4598	ABC transporter
F9K57_11435	COG4160	amino acid transport
F9K57_11440	COG4215	(ABC) transporter
F9K57_11455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9K57_11465	COG1538	Outer membrane efflux protein
F9K57_11500	COG1131	(ABC) transporter
F9K57_11505	COG0842	Transport permease protein
F9K57_11520	COG0772	Belongs to the SEDS family
F9K57_11525	COG2951	lytic endotransglycosylase activity
F9K57_11550	COG2207	Transcriptional regulator
F9K57_11565	COG0052	Belongs to the universal ribosomal protein uS2 family
F9K57_11570	COG0024	Methionine aminopeptidase
F9K57_11580	COG2223	nitrite transmembrane transporter activity
F9K57_11590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F9K57_11595	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
F9K57_11600	COG1960	acyl-CoA dehydrogenase activity
F9K57_11615	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
F9K57_11620	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
F9K57_11625	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F9K57_11645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F9K57_11650	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
F9K57_11655	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F9K57_11690	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
F9K57_11705	COG3104	oligopeptide transport
F9K57_11715	COG0512	Glutamine amidotransferase of anthranilate synthase
F9K57_11720	COG0308	aminopeptidase N
F9K57_11750	COG1529	Aldehyde oxidase and xanthine dehydrogenase
F9K57_11780	COG3739	integral membrane protein
F9K57_11805	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
F9K57_11810	COG5265	(ABC) transporter
F9K57_11815	COG1132	(ABC) transporter
F9K57_11830	COG1535	isochorismatase
F9K57_11830	COG3433	isochorismatase activity
F9K57_11835	COG1021	2,3-dihydroxybenzoate-AMP ligase
F9K57_11840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F9K57_11850	COG4774	siderophore transport
F9K57_11855	COG4607	ABC-type enterochelin transport system periplasmic component
F9K57_11860	COG4604	ABC transporter, ATP-binding protein
F9K57_11865	COG4605	iron ion homeostasis
F9K57_11870	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F9K57_11890	COG2964	Protein conserved in bacteria
F9K57_11900	COG1741	Belongs to the pirin family
F9K57_11940	COG2879	small protein
F9K57_11945	COG1966	Carbon starvation protein
F9K57_11965	COG4943	cyclic-guanylate-specific phosphodiesterase activity
F9K57_11990	COG1067	ATP-dependent peptidase activity
F9K57_11995	COG0583	DNA-binding transcription factor activity
F9K57_12020	COG1686	Belongs to the peptidase S11 family
F9K57_12025	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F9K57_12060	COG0616	signal peptide processing
F9K57_12065	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F9K57_12075	COG0573	inorganic phosphate transmembrane transporter activity
F9K57_12080	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
F9K57_12085	COG1113	amino acid transport
F9K57_12090	COG3961	Belongs to the TPP enzyme family
F9K57_12095	COG1522	sequence-specific DNA binding
F9K57_12105	COG0076	glutamate decarboxylase activity
F9K57_12110	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F9K57_12125	COG2249	NAD(P)H dehydrogenase (quinone) activity
F9K57_12135	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F9K57_12170	COG0352	thiamine-phosphate diphosphorylase activity
F9K57_12195	COG0612	Peptidase, M16
F9K57_12210	COG0583	DNA-binding transcription factor activity
F9K57_12215	COG0477	Major facilitator Superfamily
F9K57_12240	COG1187	pseudouridine synthase activity
F9K57_12255	COG1686	Belongs to the peptidase S11 family
F9K57_12260	COG1252	NADH dehydrogenase
F9K57_12270	COG0415	Belongs to the DNA photolyase family
F9K57_12285	COG1215	transferase activity, transferring glycosyl groups
F9K57_12315	COG2070	2-Nitropropane dioxygenase
F9K57_12370	COG0556	nucleotide-excision repair
F9K57_12430	COG4221	oxidoreductase activity
F9K57_12440	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
F9K57_12445	COG1381	Involved in DNA repair and RecF pathway recombination
F9K57_12455	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
F9K57_12470	COG0681	Belongs to the peptidase S26 family
F9K57_12485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F9K57_12505	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F9K57_12510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F9K57_12515	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
F9K57_12525	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
F9K57_12530	COG4208	sulfate ABC transporter
F9K57_12535	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
F9K57_12540	COG0583	DNA-binding transcription factor activity
F9K57_12545	COG4625	pathogenesis
F9K57_12560	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
F9K57_12575	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F9K57_12585	COG1051	belongs to the nudix hydrolase family
F9K57_12585	COG1056	cytidyltransferase-related domain
F9K57_12590	COG1024	Enoyl-CoA hydratase
F9K57_12595	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
F9K57_12600	COG2814	Major facilitator Superfamily
F9K57_12605	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F9K57_12605	COG0047	phosphoribosylformylglycinamidine synthase activity
F9K57_12625	COG1473	amidohydrolase
F9K57_12630	COG0824	Thioesterase
F9K57_12650	COG0823	Involved in the tonB-independent uptake of proteins
F9K57_12670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F9K57_12705	COG0628	permease
F9K57_12715	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F9K57_12720	COG0596	Alpha beta hydrolase
F9K57_12725	COG0616	signal peptide processing
F9K57_12725	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
F9K57_12735	COG0658	competence protein
F9K57_12735	COG2333	competence protein COMEC
F9K57_12740	COG1136	(ABC) transporter
F9K57_12745	COG4591	ABC-type transport system involved in lipoprotein release permease component
F9K57_12775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9K57_12795	COG0463	Glycosyl transferase, family 2
F9K57_12825	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
F9K57_12830	COG1280	lysine exporter protein (LysE YggA)
F9K57_12835	COG2267	carboxylic ester hydrolase activity
F9K57_12845	COG0019	diaminopimelate decarboxylase activity
F9K57_12855	COG1113	amino acid transport
F9K57_12870	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
F9K57_12880	COG3339	Conserved Protein
F9K57_12885	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
F9K57_12895	COG0243	molybdopterin cofactor binding
F9K57_12900	COG1929	Belongs to the glycerate kinase type-1 family
F9K57_12915	COG0778	Nitroreductase
F9K57_12940	COG3811	Belongs to the UPF0386 family
F9K57_12990	COG0741	lytic transglycosylase activity
F9K57_13010	COG0584	glycerophosphoryl diester phosphodiesterase
F9K57_13015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F9K57_13040	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F9K57_13065	COG0477	Major facilitator Superfamily
F9K57_13075	COG2264	protein methyltransferase activity
F9K57_13115	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
F9K57_13120	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F9K57_13145	COG0505	Belongs to the CarA family
F9K57_13160	COG1309	transcriptional regulator
F9K57_13165	COG0251	oxidation-reduction process
F9K57_13175	COG0589	response to stress
F9K57_13190	COG2843	Capsule synthesis protein
F9K57_13210	COG2321	neutral zinc metallopeptidase
F9K57_13215	COG2354	Protein conserved in bacteria
F9K57_13235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F9K57_13260	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F9K57_13265	COG1053	succinate dehydrogenase
F9K57_13270	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
F9K57_13275	COG2009	succinate dehydrogenase
F9K57_13315	COG2921	Belongs to the UPF0250 family
F9K57_13320	COG0321	lipoyl(octanoyl) transferase activity
F9K57_13335	COG0531	amino acid
F9K57_13350	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
F9K57_13355	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F9K57_13355	COG1648	precorrin-2 dehydrogenase activity
F9K57_13370	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
F9K57_13400	COG0671	phosphoesterase, PA-phosphatase related
F9K57_13405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9K57_13415	COG1538	Outer membrane efflux protein
F9K57_13420	COG0393	Putative heavy-metal-binding
F9K57_13425	COG0393	Putative heavy-metal-binding
F9K57_13435	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_13445	COG0525	valine-tRNA ligase activity
F9K57_13470	COG0583	DNA-binding transcription factor activity
F9K57_13480	COG0004	ammonium transporteR
F9K57_13490	COG0642	Histidine kinase
F9K57_13495	COG0745	RESPONSE REGULATOR receiver
F9K57_13500	COG2194	sulfuric ester hydrolase activity
F9K57_13520	COG1752	Esterase of the alpha-beta hydrolase superfamily
F9K57_13535	COG2315	Protein conserved in bacteria
F9K57_13540	COG0142	geranyltranstransferase activity
F9K57_13545	COG2828	Protein conserved in bacteria
F9K57_13550	COG1113	amino acid transport
F9K57_13570	COG2207	Transcriptional regulator
F9K57_13595	COG2249	NAD(P)H dehydrogenase (quinone) activity
F9K57_13615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F9K57_13625	COG1530	ribonuclease E activity
F9K57_13630	COG0424	maF-like protein
F9K57_13635	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
F9K57_13640	COG1792	Involved in formation and maintenance of cell shape
F9K57_13645	COG1077	Cell shape determining protein MreB Mrl
F9K57_13650	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
F9K57_13660	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
F9K57_13690	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
F9K57_13695	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F9K57_13700	COG1752	Esterase of the alpha-beta hydrolase superfamily
F9K57_13705	COG1115	amino acid carrier protein
F9K57_13730	COG1289	transmembrane transporter activity
F9K57_13780	COG1376	ErfK ybiS ycfS ynhG family protein
F9K57_13785	COG2832	Protein of unknown function (DUF454)
F9K57_13795	COG5510	response to toxic substance
F9K57_13815	COG0840	transmembrane signaling receptor activity
F9K57_13855	COG3422	double-strand break repair
F9K57_13860	COG2824	Alkylphosphonate utilization operon protein PhnA
F9K57_13865	COG3189	MarR family transcriptional regulator
F9K57_13875	COG0354	folic acid binding
F9K57_13880	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F9K57_13890	COG0679	Auxin Efflux Carrier
F9K57_13895	COG1902	pentaerythritol trinitrate reductase activity
F9K57_13900	COG4772	TonB-dependent receptor
F9K57_13905	COG2094	Belongs to the DNA glycosylase MPG family
F9K57_13935	COG2233	PERMEase
F9K57_13945	COG0833	amino acid
F9K57_13950	COG1690	Belongs to the RtcB family
F9K57_13955	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
F9K57_13955	COG2885	chlorophyll binding
F9K57_13965	COG0183	Belongs to the thiolase family
F9K57_13985	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F9K57_14005	COG2207	Transcriptional regulator
F9K57_14010	COG0183	Belongs to the thiolase family
F9K57_14040	COG1272	protein, Hemolysin III
F9K57_14045	COG0477	Major facilitator Superfamily
F9K57_14060	COG0450	alkyl hydroperoxide reductase
F9K57_14080	COG0285	dihydrofolate synthase activity
F9K57_14115	COG0133	tryptophan synthase activity
F9K57_14125	COG4206	TonB-dependent receptor
F9K57_14130	COG2096	Adenosyltransferase
F9K57_14135	COG0584	glycerophosphoryl diester phosphodiesterase
F9K57_14150	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
F9K57_14155	COG0745	RESPONSE REGULATOR receiver
F9K57_14160	COG2205	protein histidine kinase activity
F9K57_14170	COG1960	acyl-CoA dehydrogenase activity
F9K57_14175	COG1960	acyl-CoA dehydrogenase activity
F9K57_14180	COG3223	Belongs to the PsiE family
F9K57_14240	COG0438	transferase activity, transferring glycosyl groups
F9K57_14245	COG0463	Glycosyl transferase, family 2
F9K57_14250	COG0726	polysaccharide deacetylase
F9K57_14270	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
F9K57_14275	COG2205	protein histidine kinase activity
F9K57_14310	COG1862	Preprotein translocase
F9K57_14320	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F9K57_14325	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F9K57_14335	COG3781	membrane
F9K57_14340	COG0613	PHP domain protein
F9K57_14350	COG2350	Protein conserved in bacteria
F9K57_14380	COG1607	acyl-coa hydrolase
F9K57_14395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F9K57_14395	COG3453	Protein conserved in bacteria
F9K57_14450	COG1408	metallophosphoesterase
F9K57_14455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F9K57_14465	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F9K57_14485	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F9K57_14490	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
F9K57_14505	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
F9K57_14515	COG2969	positive regulation of protein catabolic process
F9K57_14535	COG1960	acyl-CoA dehydrogenase activity
F9K57_14540	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F9K57_14560	COG1309	transcriptional regulator
F9K57_14565	COG1960	acyl-CoA dehydrogenase activity
F9K57_14615	COG1183	phosphatidylcholine synthase activity
F9K57_14620	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
F9K57_14650	COG0741	lytic transglycosylase activity
F9K57_14650	COG1196	nuclear chromosome segregation
F9K57_14650	COG0739	heme binding
F9K57_14660	COG1702	phosphate starvation-inducible protein PhoH
F9K57_14695	COG1295	ribonuclease BN
F9K57_14700	COG0697	spore germination
F9K57_14705	COG2169	Transcriptional regulator
F9K57_14710	COG0179	Fumarylacetoacetate (FAA) hydrolase
F9K57_14755	COG0557	exoribonuclease II activity
F9K57_14760	COG0339	signal peptide processing
F9K57_14765	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
F9K57_14795	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
F9K57_14800	COG1960	acyl-CoA dehydrogenase activity
F9K57_14825	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
F9K57_14835	COG0257	Belongs to the bacterial ribosomal protein bL36 family
F9K57_14955	COG0626	cystathionine gamma-synthase activity
F9K57_14960	COG0433	COG0433 Predicted ATPase
F9K57_14970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F9K57_14970	COG1017	nitric oxide dioxygenase activity
F9K57_14975	COG1959	2 iron, 2 sulfur cluster binding
F9K57_14990	COG1301	dicarboxylic acid transport
F9K57_14995	COG1946	Acyl-CoA thioesterase
F9K57_15015	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F9K57_15020	COG1040	competence protein
F9K57_15025	COG0494	nUDIX hydrolase
F9K57_15035	COG0598	Magnesium transport protein CorA
F9K57_15045	COG2854	intermembrane phospholipid transfer
F9K57_15055	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F9K57_15060	COG1127	ABC transporter
F9K57_15065	COG0513	Belongs to the DEAD box helicase family
F9K57_15085	COG0408	coproporphyrinogen oxidase activity
F9K57_15100	COG1960	acyl-CoA dehydrogenase activity
F9K57_15115	COG0517	IMP dehydrogenase activity
F9K57_15165	COG0583	DNA-binding transcription factor activity
F9K57_15205	COG1012	belongs to the aldehyde dehydrogenase family
F9K57_15215	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F9K57_15220	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F9K57_15225	COG0833	amino acid
F9K57_15255	COG1192	Involved in chromosome partitioning
F9K57_15260	COG0628	permease
F9K57_15270	COG1289	transmembrane transporter activity
F9K57_15285	COG2249	NAD(P)H dehydrogenase (quinone) activity
F9K57_15290	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
F9K57_15300	COG0277	FAD linked oxidase domain protein
F9K57_15305	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F9K57_15330	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
F9K57_15335	COG5380	lipid catabolic process
F9K57_15355	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
F9K57_15410	COG0194	GDP metabolic process
F9K57_15425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F9K57_15455	COG4969	Belongs to the N-Me-Phe pilin family
F9K57_15465	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
F9K57_15470	COG1704	LemA family
F9K57_15480	COG0493	'glutamate synthase
F9K57_15485	COG0070	glutamate synthase
F9K57_15485	COG0069	glutamate synthase activity
F9K57_15485	COG0067	glutamate synthase
F9K57_15535	COG2226	methyltransferase
F9K57_15550	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
F9K57_15555	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F9K57_15605	COG0833	amino acid
F9K57_15670	COG0488	(ABC) transporter
F9K57_15680	COG4221	oxidoreductase activity
F9K57_15685	COG0659	secondary active sulfate transmembrane transporter activity
F9K57_15700	COG0745	RESPONSE REGULATOR receiver
F9K57_15715	COG0427	acetyl-CoA hydrolase
F9K57_15745	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
F9K57_15785	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
F9K57_15855	COG2249	NAD(P)H dehydrogenase (quinone) activity
F9K57_15865	COG1733	regulation of RNA biosynthetic process
F9K57_15900	COG0667	Aldo Keto reductase
F9K57_15925	COG0583	DNA-binding transcription factor activity
F9K57_15930	COG2814	Major facilitator Superfamily
F9K57_15960	COG1335	isochorismatase
F9K57_15970	COG1012	belongs to the aldehyde dehydrogenase family
F9K57_15975	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F9K57_15985	COG1113	amino acid transport
F9K57_16010	COG2814	Major facilitator Superfamily
F9K57_16020	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
F9K57_16020	COG0352	thiamine-phosphate diphosphorylase activity
F9K57_16020	COG0351	phosphomethylpyrimidine kinase
F9K57_16040	COG1309	transcriptional regulator
F9K57_16060	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F9K57_16070	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F9K57_16075	COG3162	membrane
F9K57_16080	COG2205	protein histidine kinase activity
F9K57_16080	COG2198	Histidine kinase
F9K57_16080	COG0784	Response regulator, receiver
F9K57_16105	COG1522	sequence-specific DNA binding
F9K57_16110	COG1335	isochorismatase
F9K57_16115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F9K57_16125	COG0668	transmembrane transport
F9K57_16130	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F9K57_16135	COG1519	Transferase
F9K57_16140	COG1902	pentaerythritol trinitrate reductase activity
F9K57_16160	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
F9K57_16185	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F9K57_16185	COG0426	domain, Protein
F9K57_16195	COG2119	membrane
F9K57_16205	COG0508	dehydrogenase complex catalyzes the overall conversion of
F9K57_16215	COG4942	peptidase
F9K57_16240	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
F9K57_16260	COG0189	ligase activity
F9K57_16280	COG0708	Exodeoxyribonuclease III
F9K57_16285	COG1393	Belongs to the ArsC family
F9K57_16300	COG3706	GGDEF domain
F9K57_16335	COG2351	hydroxyisourate hydrolase activity
F9K57_16340	COG2233	PERMEase
F9K57_16350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F9K57_16360	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
F9K57_16370	COG3150	esterase
F9K57_16395	COG2918	glutathione biosynthetic process
F9K57_16410	COG2733	membrane
F9K57_16415	COG0436	Aminotransferase
F9K57_16420	COG0534	Mate efflux family protein
F9K57_16515	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
F9K57_16520	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
F9K57_16530	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F9K57_16560	COG0010	Belongs to the arginase family
F9K57_16590	COG2188	Transcriptional regulator
F9K57_16600	COG0523	cobalamin synthesis protein
F9K57_16610	COG1113	amino acid transport
F9K57_16620	COG0625	glutathione transferase activity
F9K57_16640	COG1683	Conserved Protein
F9K57_16645	COG0534	Mate efflux family protein
F9K57_16650	COG0385	Bile acid
F9K57_16655	COG1335	isochorismatase
F9K57_16660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F9K57_16680	COG2116	formate transmembrane transporter activity
F9K57_16685	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F9K57_16700	COG3188	usher protein
F9K57_16705	COG3121	Chaperone
F9K57_16715	COG2983	Belongs to the UPF0260 family
F9K57_16735	COG1194	a g-specific adenine glycosylase
F9K57_16750	COG2818	Glycosylase
F9K57_16755	COG1064	alcohol dehydrogenase
F9K57_16760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F9K57_16775	COG0583	DNA-binding transcription factor activity
F9K57_16780	COG0656	L-ascorbic acid biosynthetic process
F9K57_16785	COG2814	Major facilitator Superfamily
F9K57_16820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9K57_16835	COG2233	PERMEase
F9K57_16840	COG0583	DNA-binding transcription factor activity
F9K57_16865	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
F9K57_16875	COG0733	neurotransmitter:sodium symporter activity
F9K57_16920	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
F9K57_16925	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
F9K57_16930	COG0596	Alpha beta hydrolase
F9K57_16955	COG0488	(ABC) transporter
F9K57_16960	COG0586	Pfam SNARE associated Golgi protein
F9K57_16970	COG0187	DNA topoisomerase II activity
F9K57_16980	COG0592	DNA-directed DNA polymerase activity
F9K57_16990	COG0230	Belongs to the bacterial ribosomal protein bL34 family
F9K57_17005	COG0706	membrane insertase activity
F9K57_17025	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F9K57_17040	COG0402	S-adenosylhomocysteine deaminase activity
F9K57_17050	COG0754	glutathionylspermidine amidase activity
F9K57_17060	COG0861	Integral membrane protein TerC family
F9K57_17065	COG0671	phosphoesterase, PA-phosphatase related
F9K57_17075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F9K57_17095	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
F9K57_17100	COG2951	lytic endotransglycosylase activity
F9K57_17155	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F9K57_17195	COG1047	Peptidyl-prolyl cis-trans
F9K57_17210	COG0196	riboflavin kinase activity
F9K57_17220	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F9K57_17230	COG1116	anion transmembrane transporter activity
F9K57_17235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F9K57_17240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F9K57_17250	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F9K57_17270	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_17275	COG0546	phosphoglycolate phosphatase activity
F9K57_17330	COG3023	N-Acetylmuramoyl-L-alanine amidase
F9K57_17335	COG0728	peptidoglycan biosynthetic process
F9K57_17365	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
F9K57_17410	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
F9K57_17415	COG0297	glycogen (starch) synthase activity
F9K57_17420	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F9K57_17430	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F9K57_17440	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F9K57_17455	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F9K57_17465	COG2186	Transcriptional regulator
F9K57_17475	COG0277	FAD linked oxidase domain protein
F9K57_17480	COG1448	Aminotransferase
F9K57_17490	COG1802	Transcriptional regulator
F9K57_17505	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F9K57_17530	COG1051	belongs to the nudix hydrolase family
F9K57_17555	COG0564	pseudouridine synthase activity
F9K57_17580	COG1522	sequence-specific DNA binding
F9K57_17595	COG0251	oxidation-reduction process
F9K57_17600	COG1113	amino acid transport
F9K57_17605	COG1113	amino acid transport
F9K57_17625	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F9K57_17630	COG1960	acyl-CoA dehydrogenase activity
F9K57_17635	COG1024	Enoyl-CoA hydratase
F9K57_17640	COG1024	Enoyl-CoA hydratase
F9K57_17645	COG0477	Major facilitator Superfamily
F9K57_17650	COG2197	response regulator
F9K57_17675	COG0271	Belongs to the BolA IbaG family
F9K57_17685	COG1192	Involved in chromosome partitioning
F9K57_17700	COG0586	Pfam SNARE associated Golgi protein
F9K57_17705	COG2259	Doxx family
F9K57_17710	COG4399	Belongs to the UPF0754 family
F9K57_17715	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F9K57_17715	COG0519	Catalyzes the synthesis of GMP from XMP
F9K57_17760	COG0281	malic enzyme
F9K57_17765	COG2837	iron assimilation
F9K57_17770	COG1280	lysine exporter protein (LysE YggA)
F9K57_17775	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F9K57_17780	COG1121	(ABC) transporter
F9K57_17845	COG0386	Belongs to the glutathione peroxidase family
F9K57_17860	COG1309	transcriptional regulator
F9K57_17865	COG0697	spore germination
F9K57_17875	COG0758	DNA mediated transformation
F9K57_17910	COG1309	transcriptional regulator
F9K57_17945	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F9K57_17955	COG0655	NAD(P)H dehydrogenase (quinone) activity
F9K57_17990	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F9K57_18000	COG0477	Major facilitator Superfamily
F9K57_18010	COG1253	flavin adenine dinucleotide binding
F9K57_18015	COG3012	SEC-C Motif Domain Protein
F9K57_18020	COG2860	membrane
F9K57_18025	COG0477	Major facilitator Superfamily
F9K57_18035	COG0318	PFAM AMP-dependent synthetase and ligase
F9K57_18050	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
F9K57_18065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F9K57_18075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F9K57_18080	COG0606	chelatase, subunit chli
F9K57_18090	COG0347	Belongs to the P(II) protein family
F9K57_18095	COG0004	ammonium transporteR
F9K57_18105	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F9K57_18105	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F9K57_18145	COG0795	lipopolysaccharide-transporting ATPase activity
F9K57_18150	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
F9K57_18155	COG0793	Belongs to the peptidase S41A family
F9K57_18170	COG2197	response regulator
F9K57_18180	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
F9K57_18190	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F9K57_18220	COG0772	Belongs to the SEDS family
F9K57_18225	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F9K57_18230	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F9K57_18235	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F9K57_18240	COG0494	nUDIX hydrolase