locus-tag	class	description
H4B47_00300	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H4B47_00325	COG3384	dioxygenase
H4B47_00335	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H4B47_00340	COG2878	Part of a membrane complex involved in electron transport
H4B47_00345	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H4B47_00370	COG0768	penicillin binding
H4B47_00375	COG0742	ribosomal rna small subunit methyltransferase
H4B47_00390	COG0830	nickel cation binding
H4B47_00400	COG0804	urea catabolic process
H4B47_00440	COG1253	flavin adenine dinucleotide binding
H4B47_00445	COG2851	Citrate transporter
H4B47_00495	COG1773	rubredoxin
H4B47_00500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H4B47_00510	COG0583	DNA-binding transcription factor activity
H4B47_00540	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H4B47_00545	COG4181	ATPase activity
H4B47_00590	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H4B47_00610	COG0306	phosphate transporter
H4B47_00620	COG3958	Transketolase
H4B47_00625	COG3959	Transketolase, thiamine diphosphate binding domain
H4B47_00630	COG2271	Major facilitator Superfamily
H4B47_00635	COG1028	Short-chain dehydrogenase reductase Sdr
H4B47_00640	COG0583	DNA-binding transcription factor activity
H4B47_00655	COG2223	nitrite transmembrane transporter activity
H4B47_00660	COG2207	Transcriptional regulator
H4B47_00665	COG2066	Belongs to the glutaminase family
H4B47_00670	COG0242	peptide deformylase activity
H4B47_00675	COG0477	Major facilitator Superfamily
H4B47_00685	COG0028	Belongs to the TPP enzyme family
H4B47_00700	COG1028	Short-chain dehydrogenase reductase Sdr
H4B47_00705	COG2267	carboxylic ester hydrolase activity
H4B47_00715	COG2271	Major facilitator Superfamily
H4B47_00730	COG1028	Short-chain dehydrogenase reductase Sdr
H4B47_00750	COG1414	Transcriptional regulator
H4B47_00765	COG1024	Enoyl-CoA hydratase
H4B47_00775	COG1215	transferase activity, transferring glycosyl groups
H4B47_00780	COG0726	polysaccharide deacetylase
H4B47_00780	COG1649	PFAM Uncharacterised BCR, COG1649
H4B47_00790	COG4681	YaeQ
H4B47_00800	COG0523	cobalamin synthesis protein
H4B47_00810	COG1607	acyl-coa hydrolase
H4B47_00820	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H4B47_00825	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H4B47_00830	COG1309	transcriptional regulator
H4B47_00855	COG2040	homocysteine
H4B47_00860	COG0531	amino acid
H4B47_00910	COG0477	Major facilitator Superfamily
H4B47_00955	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
H4B47_00970	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
H4B47_00975	COG2963	transposase activity
H4B47_01025	COG0629	single-stranded DNA binding
H4B47_01065	COG0582	viral genome integration into host DNA
H4B47_01075	COG0405	Gamma-glutamyltransferase
H4B47_01080	COG2814	Major facilitator Superfamily
H4B47_01090	COG2050	protein possibly involved in aromatic compounds catabolism
H4B47_01105	COG1090	epimerase
H4B47_01125	COG0420	3'-5' exonuclease activity
H4B47_01150	COG0735	belongs to the Fur family
H4B47_01155	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H4B47_01175	COG0121	glutamine amidotransferase
H4B47_01190	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H4B47_01200	COG0210	DNA helicase
H4B47_01205	COG2885	chlorophyll binding
H4B47_01210	COG0204	Acyl-transferase
H4B47_01225	COG2894	cell division
H4B47_01240	COG1280	lysine exporter protein (LysE YggA)
H4B47_01245	COG1674	ftsk spoiiie
H4B47_01245	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H4B47_01250	COG0492	ferredoxin-NADP+ reductase activity
H4B47_01255	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H4B47_01265	COG0456	acetyltransferase
H4B47_01310	COG1981	membrane
H4B47_01325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H4B47_01325	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H4B47_01345	COG1012	belongs to the aldehyde dehydrogenase family
H4B47_01355	COG0657	acetylesterase activity
H4B47_01365	COG0473	3-isopropylmalate dehydrogenase activity
H4B47_01370	COG0583	DNA-binding transcription factor activity
H4B47_01390	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H4B47_01415	COG0564	pseudouridine synthase activity
H4B47_01425	COG0358	DNA primase activity
H4B47_01440	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
H4B47_01470	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H4B47_01500	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H4B47_01510	COG0352	thiamine-phosphate diphosphorylase activity
H4B47_01510	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H4B47_01510	COG0351	phosphomethylpyrimidine kinase
H4B47_01515	COG1652	LysM domain
H4B47_01540	COG1399	metal-binding, possibly nucleic acid-binding protein
H4B47_01545	COG3101	peptidyl-lysine hydroxylation
H4B47_01550	COG0009	L-threonylcarbamoyladenylate synthase
H4B47_01555	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H4B47_01560	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H4B47_01575	COG4106	trans-aconitate 2-methyltransferase activity
H4B47_01590	COG2226	methyltransferase
H4B47_01590	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H4B47_01590	COG0596	Alpha beta hydrolase
H4B47_01595	COG1877	trehalose-phosphatase activity
H4B47_01600	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H4B47_01605	COG2223	nitrite transmembrane transporter activity
H4B47_01625	COG1196	nuclear chromosome segregation
H4B47_01635	COG0730	response to heat
H4B47_01650	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H4B47_01660	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H4B47_01710	COG0489	protein tyrosine kinase activity
H4B47_01720	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H4B47_01720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H4B47_01750	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H4B47_01755	COG2081	HI0933 family
H4B47_01765	COG0668	transmembrane transport
H4B47_01785	COG0583	DNA-binding transcription factor activity
H4B47_01810	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H4B47_01815	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H4B47_01845	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H4B47_01870	COG3706	GGDEF domain
H4B47_01885	COG0745	RESPONSE REGULATOR receiver
H4B47_01905	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H4B47_01955	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H4B47_01970	COG0583	DNA-binding transcription factor activity
H4B47_01980	COG0583	DNA-binding transcription factor activity
H4B47_01995	COG0583	DNA-binding transcription factor activity
H4B47_02000	COG1053	succinate dehydrogenase
H4B47_02015	COG1309	transcriptional regulator
H4B47_02020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H4B47_02025	COG2814	Major facilitator Superfamily
H4B47_02030	COG1960	acyl-CoA dehydrogenase activity
H4B47_02035	COG0583	DNA-binding transcription factor activity
H4B47_02040	COG1063	alcohol dehydrogenase
H4B47_02070	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H4B47_02075	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H4B47_02080	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H4B47_02100	COG2132	Multicopper oxidase
H4B47_02110	COG0561	phosphatase activity
H4B47_02115	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H4B47_02140	COG1214	PFAM Peptidase M22, glycoprotease
H4B47_02180	COG2963	transposase activity
H4B47_02220	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H4B47_02225	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H4B47_02230	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H4B47_02290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H4B47_02300	COG1846	Transcriptional regulator
H4B47_02305	COG1764	response to oxidative stress
H4B47_02345	COG0037	tRNA processing
H4B47_02355	COG0248	Ppx GppA phosphatase
H4B47_02385	COG0072	phenylalanine-tRNA ligase activity
H4B47_02425	COG1238	metal cluster binding
H4B47_02430	COG0625	glutathione transferase activity
H4B47_02445	COG0318	PFAM AMP-dependent synthetase and ligase
H4B47_02450	COG3028	Belongs to the UPF0307 family
H4B47_02455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H4B47_02475	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H4B47_02480	COG0617	tRNA 3'-terminal CCA addition
H4B47_02485	COG1555	photosystem II stabilization
H4B47_02490	COG3956	TIGRFAM MazG family protein
H4B47_02500	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H4B47_02520	COG0784	Response regulator, receiver
H4B47_02520	COG5002	protein histidine kinase activity
H4B47_02520	COG2205	protein histidine kinase activity
H4B47_02525	COG1024	Enoyl-CoA hydratase
H4B47_02530	COG2084	Dehydrogenase
H4B47_02535	COG3622	Belongs to the hyi family
H4B47_02565	COG0697	spore germination
H4B47_02575	COG2814	Major facilitator Superfamily
H4B47_02580	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H4B47_02600	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H4B47_02610	COG0084	hydrolase, TatD family'
H4B47_02625	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H4B47_02655	COG0440	acetolactate synthase activity
H4B47_02660	COG0028	Belongs to the TPP enzyme family
H4B47_02685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H4B47_02690	COG1136	(ABC) transporter
H4B47_02690	COG0577	efflux transmembrane transporter activity
H4B47_02695	COG1538	Outer membrane efflux protein
H4B47_02710	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H4B47_02715	COG1162	GTPase activity
H4B47_02725	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H4B47_02765	COG1426	Protein conserved in bacteria
H4B47_02800	COG0793	Belongs to the peptidase S41A family
H4B47_02815	COG2267	carboxylic ester hydrolase activity
H4B47_02825	COG1012	belongs to the aldehyde dehydrogenase family
H4B47_02830	COG3265	gluconokinase activity
H4B47_02840	COG0800	Aldolase
H4B47_02850	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H4B47_02855	COG0857	belongs to the CobB CobQ family
H4B47_02855	COG0280	phosphate acetyltransferase
H4B47_02860	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H4B47_02860	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H4B47_02880	COG0740	serine-type endopeptidase activity
H4B47_02890	COG4774	siderophore transport
H4B47_02900	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H4B47_02910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H4B47_02910	COG2813	Specifically methylates the guanine in position
H4B47_03025	COG3039	Transposase
H4B47_03070	COG3550	peptidyl-serine autophosphorylation
H4B47_03100	COG0789	Transcriptional regulator
H4B47_03175	COG0482	sulfurtransferase activity
H4B47_03190	COG0488	(ABC) transporter
H4B47_03195	COG3173	Aminoglycoside phosphotransferase
H4B47_03290	COG1192	Involved in chromosome partitioning
H4B47_03340	COG1126	abc transporter atp-binding protein
H4B47_03360	COG2188	Transcriptional regulator
H4B47_03370	COG0523	cobalamin synthesis protein
H4B47_03380	COG1113	amino acid transport
H4B47_03390	COG0625	glutathione transferase activity
H4B47_03410	COG1683	Conserved Protein
H4B47_03420	COG0385	Bile acid
H4B47_03425	COG1335	isochorismatase
H4B47_03430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H4B47_03450	COG2116	formate transmembrane transporter activity
H4B47_03455	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H4B47_03460	COG2133	pyrroloquinoline quinone binding
H4B47_03465	COG2983	Belongs to the UPF0260 family
H4B47_03485	COG1194	a g-specific adenine glycosylase
H4B47_03500	COG2818	Glycosylase
H4B47_03505	COG1064	alcohol dehydrogenase
H4B47_03510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H4B47_03525	COG0583	DNA-binding transcription factor activity
H4B47_03530	COG0656	L-ascorbic acid biosynthetic process
H4B47_03535	COG2814	Major facilitator Superfamily
H4B47_03570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H4B47_03585	COG2233	PERMEase
H4B47_03590	COG0583	DNA-binding transcription factor activity
H4B47_03625	COG0733	neurotransmitter:sodium symporter activity
H4B47_03670	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H4B47_03675	COG0657	acetylesterase activity
H4B47_03725	COG2951	lytic endotransglycosylase activity
H4B47_03730	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H4B47_03745	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H4B47_03755	COG0671	phosphoesterase, PA-phosphatase related
H4B47_03760	COG0861	Integral membrane protein TerC family
H4B47_03770	COG0754	glutathionylspermidine amidase activity
H4B47_03780	COG0402	S-adenosylhomocysteine deaminase activity
H4B47_03795	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H4B47_03800	COG1230	cation diffusion facilitator family transporter
H4B47_03815	COG0706	membrane insertase activity
H4B47_03840	COG0592	DNA-directed DNA polymerase activity
H4B47_03850	COG0187	DNA topoisomerase II activity
H4B47_03860	COG0586	Pfam SNARE associated Golgi protein
H4B47_03865	COG0488	(ABC) transporter
H4B47_03890	COG0596	Alpha beta hydrolase
H4B47_03895	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H4B47_03900	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H4B47_03940	COG1047	Peptidyl-prolyl cis-trans
H4B47_03950	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H4B47_03955	COG0196	riboflavin kinase activity
H4B47_03965	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H4B47_03970	COG1309	transcriptional regulator
H4B47_03975	COG1116	anion transmembrane transporter activity
H4B47_03980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H4B47_03985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H4B47_03990	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H4B47_03995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H4B47_04015	COG1028	Short-chain dehydrogenase reductase Sdr
H4B47_04020	COG0546	phosphoglycolate phosphatase activity
H4B47_04080	COG3023	N-Acetylmuramoyl-L-alanine amidase
H4B47_04085	COG0728	peptidoglycan biosynthetic process
H4B47_04110	COG1596	polysaccharide export
H4B47_04115	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H4B47_04125	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
H4B47_04140	COG2030	dehydratase
H4B47_04155	COG1216	Glycosyl transferase, family 2
H4B47_04155	COG0463	Glycosyl transferase, family 2
H4B47_04165	COG0438	transferase activity, transferring glycosyl groups
H4B47_04180	COG1216	Glycosyl transferase, family 2
H4B47_04185	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H4B47_04190	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H4B47_04205	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H4B47_04215	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H4B47_04225	COG2186	Transcriptional regulator
H4B47_04235	COG0277	FAD linked oxidase domain protein
H4B47_04240	COG1448	Aminotransferase
H4B47_04250	COG1802	Transcriptional regulator
H4B47_04265	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H4B47_04300	COG0564	pseudouridine synthase activity
H4B47_04340	COG0251	oxidation-reduction process
H4B47_04345	COG1113	amino acid transport
H4B47_04350	COG1113	amino acid transport
H4B47_04370	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H4B47_04375	COG1960	acyl-CoA dehydrogenase activity
H4B47_04380	COG1024	Enoyl-CoA hydratase
H4B47_04385	COG1024	Enoyl-CoA hydratase
H4B47_04390	COG0477	Major facilitator Superfamily
H4B47_04395	COG3916	Acyl-homoserine-lactone synthase
H4B47_04405	COG2197	response regulator
H4B47_04435	COG0271	Belongs to the BolA IbaG family
H4B47_04445	COG1192	Involved in chromosome partitioning
H4B47_04460	COG0586	Pfam SNARE associated Golgi protein
H4B47_04465	COG2259	Doxx family
H4B47_04470	COG4399	Belongs to the UPF0754 family
H4B47_04475	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H4B47_04475	COG0519	Catalyzes the synthesis of GMP from XMP
H4B47_04520	COG0281	malic enzyme
H4B47_04525	COG2837	iron assimilation
H4B47_04530	COG1280	lysine exporter protein (LysE YggA)
H4B47_04535	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H4B47_04540	COG1121	(ABC) transporter
H4B47_04605	COG0386	Belongs to the glutathione peroxidase family
H4B47_04620	COG1309	transcriptional regulator
H4B47_04625	COG0697	spore germination
H4B47_04635	COG0758	DNA mediated transformation
H4B47_04670	COG1309	transcriptional regulator
H4B47_04705	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H4B47_04715	COG0655	NAD(P)H dehydrogenase (quinone) activity
H4B47_04750	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H4B47_04770	COG1253	flavin adenine dinucleotide binding
H4B47_04780	COG2860	membrane
H4B47_04785	COG0477	Major facilitator Superfamily
H4B47_04795	COG0318	PFAM AMP-dependent synthetase and ligase
H4B47_04810	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H4B47_04825	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H4B47_04835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H4B47_04840	COG0606	chelatase, subunit chli
H4B47_04870	COG0589	response to stress
H4B47_04875	COG0659	secondary active sulfate transmembrane transporter activity
H4B47_04890	COG1061	Type III restriction enzyme res subunit
H4B47_04915	COG0606	chelatase, subunit chli
H4B47_04925	COG0347	Belongs to the P(II) protein family
H4B47_04930	COG0004	ammonium transporteR
H4B47_04940	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H4B47_04940	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H4B47_04980	COG0795	lipopolysaccharide-transporting ATPase activity
H4B47_04985	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H4B47_04990	COG0793	Belongs to the peptidase S41A family
H4B47_05005	COG2197	response regulator
H4B47_05015	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H4B47_05025	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H4B47_05030	COG4974	Belongs to the 'phage' integrase family
H4B47_05055	COG0772	Belongs to the SEDS family
H4B47_05060	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H4B47_05065	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H4B47_05070	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H4B47_05095	COG0697	spore germination
H4B47_05100	COG1538	Outer membrane efflux protein
H4B47_05120	COG3275	phosphorelay sensor kinase activity
H4B47_05130	COG0181	hydroxymethylbilane synthase activity
H4B47_05175	COG1716	ATPase activity
H4B47_05180	COG0546	phosphoglycolate phosphatase activity
H4B47_05275	COG0596	Alpha beta hydrolase
H4B47_05280	COG2056	Na+-H+ antiporter family
H4B47_05295	COG0326	Molecular chaperone. Has ATPase activity
H4B47_05310	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H4B47_05375	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H4B47_05380	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H4B47_05380	COG2169	Transcriptional regulator
H4B47_05410	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H4B47_05420	COG0497	DNA recombination
H4B47_05435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H4B47_05445	COG0237	dephospho-CoA kinase activity
H4B47_05495	COG0195	Participates in both transcription termination and antitermination
H4B47_05510	COG1320	monovalent cation:proton antiporter activity
H4B47_05515	COG2212	antiporter activity
H4B47_05520	COG1863	multisubunit Na H antiporter MnhE subunit
H4B47_05525	COG0651	ATP synthesis coupled electron transport
H4B47_05530	COG1006	Multisubunit Na H antiporter MnhC subunit
H4B47_05535	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H4B47_05535	COG2111	Na H antiporter
H4B47_05550	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H4B47_05555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H4B47_05570	COG2226	methyltransferase
H4B47_05590	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H4B47_05595	COG1074	ATP-dependent DNA helicase activity
H4B47_05600	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H4B47_05605	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H4B47_05620	COG0598	Magnesium transport protein CorA
H4B47_05625	COG0789	Transcriptional regulator
H4B47_05630	COG0484	heat shock protein binding
H4B47_05645	COG0475	glutathione-regulated potassium exporter activity
H4B47_05645	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H4B47_05650	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H4B47_05670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H4B47_05680	COG4535	Mg2 and Co2 transporter CorC
H4B47_05685	COG0425	Belongs to the sulfur carrier protein TusA family
H4B47_05690	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H4B47_05690	COG0644	oxidoreductase
H4B47_05700	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H4B47_05715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H4B47_05720	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H4B47_05730	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H4B47_05730	COG0493	'glutamate synthase
H4B47_05760	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H4B47_05775	COG0534	Mate efflux family protein
H4B47_05785	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H4B47_05790	COG4221	oxidoreductase activity
H4B47_05795	COG0583	DNA-binding transcription factor activity
H4B47_05810	COG0318	PFAM AMP-dependent synthetase and ligase
H4B47_05815	COG1530	ribonuclease E activity
H4B47_05825	COG0546	phosphoglycolate phosphatase activity
H4B47_05830	COG2378	regulation of single-species biofilm formation
H4B47_05835	COG0625	glutathione transferase activity
H4B47_05845	COG0583	DNA-binding transcription factor activity
H4B47_05910	COG0473	3-isopropylmalate dehydrogenase activity
H4B47_05965	COG1301	dicarboxylic acid transport
H4B47_05975	COG1560	Kdo2-lipid A biosynthetic process
H4B47_05980	COG1280	lysine exporter protein (LysE YggA)
H4B47_05985	COG0488	(ABC) transporter
H4B47_05990	COG2900	Belongs to the SlyX family
H4B47_06000	COG1733	regulation of RNA biosynthetic process
H4B47_06025	COG0210	DNA helicase
H4B47_06030	COG0724	RNA recognition motif
H4B47_06050	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H4B47_06050	COG4651	solute:proton antiporter activity
H4B47_06075	COG0788	formyltetrahydrofolate deformylase activity
H4B47_06225	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H4B47_06230	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H4B47_06240	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H4B47_06245	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H4B47_06330	COG0534	Mate efflux family protein
H4B47_06335	COG0436	Aminotransferase
H4B47_06340	COG2733	membrane
H4B47_06355	COG2918	glutathione biosynthetic process
H4B47_06400	COG3150	esterase
H4B47_06410	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
H4B47_06420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H4B47_06435	COG2351	hydroxyisourate hydrolase activity
H4B47_06470	COG3706	GGDEF domain
H4B47_06485	COG1393	Belongs to the ArsC family
H4B47_06490	COG0708	Exodeoxyribonuclease III
H4B47_06525	COG0189	ligase activity
H4B47_06545	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H4B47_06555	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H4B47_06570	COG4942	peptidase
H4B47_06580	COG0508	dehydrogenase complex catalyzes the overall conversion of
H4B47_06590	COG2119	membrane
H4B47_06595	COG4774	siderophore transport
H4B47_06600	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H4B47_06600	COG0426	domain, Protein
H4B47_06625	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H4B47_06650	COG1902	pentaerythritol trinitrate reductase activity
H4B47_06655	COG1519	Transferase
H4B47_06660	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H4B47_06665	COG0668	transmembrane transport
H4B47_06675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H4B47_06680	COG1335	isochorismatase
H4B47_06685	COG1522	sequence-specific DNA binding
H4B47_06710	COG2198	Histidine kinase
H4B47_06710	COG0784	Response regulator, receiver
H4B47_06710	COG2205	protein histidine kinase activity
H4B47_06715	COG3162	membrane
H4B47_06720	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H4B47_06750	COG1309	transcriptional regulator
H4B47_06770	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H4B47_06770	COG0352	thiamine-phosphate diphosphorylase activity
H4B47_06770	COG0351	phosphomethylpyrimidine kinase
H4B47_06780	COG2814	Major facilitator Superfamily
H4B47_06795	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H4B47_06805	COG1113	amino acid transport
H4B47_06815	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H4B47_06820	COG1012	belongs to the aldehyde dehydrogenase family
H4B47_06830	COG1335	isochorismatase
H4B47_06860	COG2814	Major facilitator Superfamily
H4B47_06865	COG0583	DNA-binding transcription factor activity
H4B47_06885	COG0667	Aldo Keto reductase
H4B47_06915	COG1733	regulation of RNA biosynthetic process
H4B47_06920	COG2249	NAD(P)H dehydrogenase (quinone) activity
H4B47_06980	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H4B47_07025	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H4B47_07055	COG0427	acetyl-CoA hydrolase
H4B47_07080	COG0659	secondary active sulfate transmembrane transporter activity
H4B47_07085	COG4221	oxidoreductase activity
H4B47_07095	COG0488	(ABC) transporter
H4B47_07160	COG0833	amino acid
H4B47_07205	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H4B47_07210	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H4B47_07225	COG2226	methyltransferase
H4B47_07275	COG0070	glutamate synthase
H4B47_07275	COG0067	glutamate synthase
H4B47_07275	COG0069	glutamate synthase activity
H4B47_07280	COG0493	'glutamate synthase
H4B47_07290	COG1704	LemA family
H4B47_07295	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H4B47_07315	COG3307	-O-antigen
H4B47_07335	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H4B47_07350	COG0194	GDP metabolic process
H4B47_07400	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H4B47_07420	COG5380	lipid catabolic process
H4B47_07425	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H4B47_07450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H4B47_07455	COG0277	FAD linked oxidase domain protein
H4B47_07470	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H4B47_07475	COG2249	NAD(P)H dehydrogenase (quinone) activity
H4B47_07490	COG1289	transmembrane transporter activity
H4B47_07500	COG0628	permease
H4B47_07505	COG1192	Involved in chromosome partitioning
H4B47_07535	COG0833	amino acid
H4B47_07540	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H4B47_07545	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H4B47_07555	COG1012	belongs to the aldehyde dehydrogenase family
H4B47_07595	COG0583	DNA-binding transcription factor activity
H4B47_07645	COG0517	IMP dehydrogenase activity
H4B47_07650	COG1983	PspC domain protein
H4B47_07660	COG1960	acyl-CoA dehydrogenase activity
H4B47_07675	COG0408	coproporphyrinogen oxidase activity
H4B47_07695	COG0513	Belongs to the DEAD box helicase family
H4B47_07705	COG1127	ABC transporter
H4B47_07710	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H4B47_07720	COG2854	intermembrane phospholipid transfer
H4B47_07730	COG0598	Magnesium transport protein CorA
H4B47_07740	COG0494	nUDIX hydrolase
H4B47_07745	COG1040	competence protein
H4B47_07750	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H4B47_07770	COG1946	Acyl-CoA thioesterase
H4B47_07775	COG1301	dicarboxylic acid transport
H4B47_07790	COG1959	2 iron, 2 sulfur cluster binding
H4B47_07795	COG1017	nitric oxide dioxygenase activity
H4B47_07795	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H4B47_07805	COG0433	COG0433 Predicted ATPase
H4B47_07810	COG0626	cystathionine gamma-synthase activity
H4B47_07965	COG1960	acyl-CoA dehydrogenase activity
H4B47_07970	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H4B47_08000	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H4B47_08005	COG0339	signal peptide processing
H4B47_08010	COG0557	exoribonuclease II activity
H4B47_08060	COG0179	Fumarylacetoacetate (FAA) hydrolase
H4B47_08065	COG2169	Transcriptional regulator
H4B47_08070	COG0697	spore germination
H4B47_08075	COG1295	ribonuclease BN
H4B47_08110	COG1702	phosphate starvation-inducible protein PhoH
H4B47_08120	COG0741	lytic transglycosylase activity
H4B47_08120	COG0739	heme binding
H4B47_08120	COG1196	nuclear chromosome segregation
H4B47_08150	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H4B47_08155	COG1183	phosphatidylcholine synthase activity
H4B47_08200	COG1960	acyl-CoA dehydrogenase activity
H4B47_08205	COG1309	transcriptional regulator
H4B47_08220	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H4B47_08225	COG1960	acyl-CoA dehydrogenase activity
H4B47_08245	COG2969	positive regulation of protein catabolic process
H4B47_08255	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H4B47_08265	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H4B47_08270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H4B47_08275	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H4B47_08295	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H4B47_08305	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H4B47_08310	COG1408	metallophosphoesterase
H4B47_08320	COG2199	diguanylate cyclase activity
H4B47_08380	COG1607	acyl-coa hydrolase
H4B47_08410	COG2350	Protein conserved in bacteria
H4B47_08420	COG0613	PHP domain protein
H4B47_08425	COG3781	membrane
H4B47_08435	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H4B47_08440	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H4B47_08450	COG1862	Preprotein translocase
H4B47_08480	COG2205	protein histidine kinase activity
H4B47_08485	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H4B47_08505	COG0726	polysaccharide deacetylase
H4B47_08510	COG0463	Glycosyl transferase, family 2
H4B47_08515	COG0438	transferase activity, transferring glycosyl groups
H4B47_08580	COG1960	acyl-CoA dehydrogenase activity
H4B47_08585	COG1960	acyl-CoA dehydrogenase activity
H4B47_08595	COG2205	protein histidine kinase activity
H4B47_08600	COG0745	RESPONSE REGULATOR receiver
H4B47_08605	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H4B47_08625	COG2096	Adenosyltransferase
H4B47_08675	COG0285	dihydrofolate synthase activity
H4B47_08695	COG0450	alkyl hydroperoxide reductase
H4B47_08710	COG0477	Major facilitator Superfamily
H4B47_08715	COG1272	protein, Hemolysin III
H4B47_08745	COG0183	Belongs to the thiolase family
H4B47_08750	COG2207	Transcriptional regulator
H4B47_08770	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H4B47_08790	COG0183	Belongs to the thiolase family
H4B47_08800	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H4B47_08800	COG2885	chlorophyll binding
H4B47_08810	COG1690	Belongs to the RtcB family
H4B47_08815	COG0833	amino acid
H4B47_08825	COG2233	PERMEase
H4B47_08830	COG1217	gtp-binding protein TYPA
H4B47_08855	COG2094	Belongs to the DNA glycosylase MPG family
H4B47_08865	COG1902	pentaerythritol trinitrate reductase activity
H4B47_08880	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H4B47_08885	COG0354	folic acid binding
H4B47_08895	COG3189	MarR family transcriptional regulator
H4B47_08900	COG2824	Alkylphosphonate utilization operon protein PhnA
H4B47_08905	COG3422	double-strand break repair
H4B47_08945	COG0840	transmembrane signaling receptor activity
H4B47_08965	COG5510	response to toxic substance
H4B47_08975	COG2832	Protein of unknown function (DUF454)
H4B47_08980	COG1376	ErfK ybiS ycfS ynhG family protein
H4B47_09020	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H4B47_09030	COG1289	transmembrane transporter activity
H4B47_09035	COG2814	Major facilitator Superfamily
H4B47_09055	COG1115	amino acid carrier protein
H4B47_09060	COG1752	Esterase of the alpha-beta hydrolase superfamily
H4B47_09065	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H4B47_09070	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H4B47_09095	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H4B47_09105	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H4B47_09110	COG1077	Cell shape determining protein MreB Mrl
H4B47_09115	COG1792	Involved in formation and maintenance of cell shape
H4B47_09120	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H4B47_09125	COG0424	maF-like protein
H4B47_09130	COG1530	ribonuclease E activity
H4B47_09140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4B47_09150	COG0560	Phosphoserine phosphatase
H4B47_09160	COG2249	NAD(P)H dehydrogenase (quinone) activity
H4B47_09185	COG2207	Transcriptional regulator
H4B47_09230	COG1113	amino acid transport
H4B47_09235	COG2828	Protein conserved in bacteria
H4B47_09245	COG0142	geranyltranstransferase activity
H4B47_09250	COG2315	Protein conserved in bacteria
H4B47_09265	COG1752	Esterase of the alpha-beta hydrolase superfamily
H4B47_09280	COG2963	transposase activity
H4B47_09305	COG0745	RESPONSE REGULATOR receiver
H4B47_09310	COG0642	Histidine kinase
H4B47_09320	COG0004	ammonium transporteR
H4B47_09325	COG0583	DNA-binding transcription factor activity
H4B47_09340	COG2226	methyltransferase
H4B47_09355	COG1028	Short-chain dehydrogenase reductase Sdr
H4B47_09365	COG0393	Putative heavy-metal-binding
H4B47_09370	COG0393	Putative heavy-metal-binding
H4B47_09385	COG2963	transposase activity
H4B47_09390	COG1538	Outer membrane efflux protein
H4B47_09400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H4B47_09405	COG0671	phosphoesterase, PA-phosphatase related
H4B47_09435	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H4B47_09450	COG1648	precorrin-2 dehydrogenase activity
H4B47_09450	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H4B47_09455	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H4B47_09460	COG1733	regulation of RNA biosynthetic process
H4B47_09470	COG0531	amino acid
H4B47_09485	COG0321	lipoyl(octanoyl) transferase activity
H4B47_09490	COG2921	Belongs to the UPF0250 family
H4B47_09530	COG2009	succinate dehydrogenase
H4B47_09535	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H4B47_09540	COG1053	succinate dehydrogenase
H4B47_09545	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H4B47_09570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H4B47_09590	COG2354	Protein conserved in bacteria
H4B47_09595	COG2321	neutral zinc metallopeptidase
H4B47_09615	COG2843	Capsule synthesis protein
H4B47_09630	COG0589	response to stress
H4B47_09650	COG0505	Belongs to the CarA family
H4B47_09675	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H4B47_09680	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H4B47_09730	COG0477	Major facilitator Superfamily
H4B47_09735	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H4B47_09750	COG1597	lipid kinase activity
H4B47_09755	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H4B47_09780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H4B47_09785	COG0584	glycerophosphoryl diester phosphodiesterase
H4B47_09805	COG0741	lytic transglycosylase activity
H4B47_09825	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H4B47_09850	COG3811	Belongs to the UPF0386 family
H4B47_09870	COG0778	Nitroreductase
H4B47_09885	COG1929	Belongs to the glycerate kinase type-1 family
H4B47_09890	COG0243	molybdopterin cofactor binding
H4B47_09895	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H4B47_09900	COG3339	Conserved Protein
H4B47_09910	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
H4B47_09925	COG1113	amino acid transport
H4B47_09935	COG0019	diaminopimelate decarboxylase activity
H4B47_09945	COG1280	lysine exporter protein (LysE YggA)
H4B47_09950	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H4B47_09980	COG0463	Glycosyl transferase, family 2
H4B47_10000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H4B47_10035	COG4591	ABC-type transport system involved in lipoprotein release permease component
H4B47_10040	COG1136	(ABC) transporter
H4B47_10045	COG2333	competence protein COMEC
H4B47_10045	COG0658	competence protein
H4B47_10055	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H4B47_10055	COG0616	signal peptide processing
H4B47_10060	COG0596	Alpha beta hydrolase
H4B47_10065	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H4B47_10075	COG0628	permease
H4B47_10105	COG2963	transposase activity
H4B47_10125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H4B47_10145	COG0823	Involved in the tonB-independent uptake of proteins
H4B47_10165	COG0824	Thioesterase
H4B47_10170	COG1473	amidohydrolase
H4B47_10190	COG0047	phosphoribosylformylglycinamidine synthase activity
H4B47_10190	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H4B47_10195	COG2814	Major facilitator Superfamily
H4B47_10205	COG1024	Enoyl-CoA hydratase
H4B47_10210	COG1056	cytidyltransferase-related domain
H4B47_10210	COG1051	belongs to the nudix hydrolase family
H4B47_10220	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H4B47_10235	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H4B47_10250	COG4625	pathogenesis
H4B47_10255	COG0583	DNA-binding transcription factor activity
H4B47_10260	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H4B47_10265	COG4208	sulfate ABC transporter
H4B47_10270	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H4B47_10280	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H4B47_10285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H4B47_10290	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H4B47_10310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H4B47_10325	COG0681	Belongs to the peptidase S26 family
H4B47_10340	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H4B47_10350	COG1381	Involved in DNA repair and RecF pathway recombination
H4B47_10355	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H4B47_10365	COG4221	oxidoreductase activity
H4B47_10395	COG0443	Heat shock 70 kDa protein
H4B47_10405	COG0436	Aminotransferase
H4B47_10425	COG0556	nucleotide-excision repair
H4B47_10480	COG2070	2-Nitropropane dioxygenase
H4B47_10510	COG1215	transferase activity, transferring glycosyl groups
H4B47_10525	COG0415	Belongs to the DNA photolyase family
H4B47_10535	COG1252	NADH dehydrogenase
H4B47_10540	COG1686	Belongs to the peptidase S11 family
H4B47_10555	COG1187	pseudouridine synthase activity
H4B47_10580	COG0477	Major facilitator Superfamily
H4B47_10585	COG0583	DNA-binding transcription factor activity
H4B47_10590	COG1823	symporter activity
H4B47_10600	COG0612	Peptidase, M16
H4B47_10625	COG0352	thiamine-phosphate diphosphorylase activity
H4B47_10660	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H4B47_10670	COG2249	NAD(P)H dehydrogenase (quinone) activity
H4B47_10685	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H4B47_10690	COG0076	glutamate decarboxylase activity
H4B47_10700	COG1522	sequence-specific DNA binding
H4B47_10705	COG3961	Belongs to the TPP enzyme family
H4B47_10710	COG1113	amino acid transport
H4B47_10715	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H4B47_10720	COG0573	inorganic phosphate transmembrane transporter activity
H4B47_10730	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H4B47_10735	COG0616	signal peptide processing
H4B47_10770	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H4B47_10780	COG1686	Belongs to the peptidase S11 family
H4B47_10805	COG0583	DNA-binding transcription factor activity
H4B47_10810	COG1067	ATP-dependent peptidase activity
H4B47_10835	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H4B47_10855	COG1966	Carbon starvation protein
H4B47_10860	COG2879	small protein
H4B47_10900	COG1335	isochorismatase
H4B47_10905	COG0583	DNA-binding transcription factor activity
H4B47_10920	COG0596	Alpha beta hydrolase
H4B47_10930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H4B47_10940	COG0583	DNA-binding transcription factor activity
H4B47_10945	COG1902	pentaerythritol trinitrate reductase activity
H4B47_10950	COG0006	proline dipeptidase activity
H4B47_10955	COG0477	Major facilitator Superfamily
H4B47_10970	COG1012	belongs to the aldehyde dehydrogenase family
H4B47_10975	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H4B47_10980	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
H4B47_10980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H4B47_11015	COG2814	Major facilitator Superfamily
H4B47_11020	COG4948	Mandelate Racemase Muconate Lactonizing
H4B47_11030	COG2963	transposase activity
H4B47_11040	COG4372	Transposase
H4B47_11050	COG1309	transcriptional regulator
H4B47_11070	COG1741	Belongs to the pirin family
H4B47_11080	COG2964	Protein conserved in bacteria
H4B47_11095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4B47_11100	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H4B47_11105	COG4605	iron ion homeostasis
H4B47_11110	COG4604	ABC transporter, ATP-binding protein
H4B47_11115	COG4607	ABC-type enterochelin transport system periplasmic component
H4B47_11120	COG4774	siderophore transport
H4B47_11130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H4B47_11135	COG1021	2,3-dihydroxybenzoate-AMP ligase
H4B47_11140	COG1535	isochorismatase
H4B47_11140	COG3433	isochorismatase activity
H4B47_11150	COG1132	(ABC) transporter
H4B47_11155	COG1132	(ABC) transporter
H4B47_11160	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H4B47_11165	COG2977	Belongs to the P-Pant transferase superfamily
H4B47_11210	COG0302	gtp cyclohydrolase
H4B47_11220	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H4B47_11250	COG0308	aminopeptidase N
H4B47_11255	COG0512	Glutamine amidotransferase of anthranilate synthase
H4B47_11645	COG0582	viral genome integration into host DNA
H4B47_11660	COG0174	glutamine synthetase
H4B47_11670	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H4B47_11705	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H4B47_11710	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H4B47_11715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H4B47_11735	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H4B47_11740	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H4B47_11745	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H4B47_11760	COG1960	acyl-CoA dehydrogenase activity
H4B47_11765	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H4B47_11770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H4B47_11780	COG2223	nitrite transmembrane transporter activity
H4B47_11790	COG0024	Methionine aminopeptidase
H4B47_11795	COG0052	Belongs to the universal ribosomal protein uS2 family
H4B47_11810	COG2207	Transcriptional regulator
H4B47_11835	COG2951	lytic endotransglycosylase activity
H4B47_11840	COG0772	Belongs to the SEDS family
H4B47_11855	COG0842	Transport permease protein
H4B47_11860	COG1131	(ABC) transporter
H4B47_11865	COG0582	viral genome integration into host DNA
H4B47_12035	COG5410	chromosome segregation
H4B47_12160	COG2963	transposase activity
H4B47_12300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H4B47_12315	COG4215	(ABC) transporter
H4B47_12320	COG4160	amino acid transport
H4B47_12325	COG4598	ABC transporter
H4B47_12335	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H4B47_12340	COG0826	peptidase U32
H4B47_12345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H4B47_12350	COG0384	phenazine biosynthesis protein PhzF
H4B47_12360	COG1720	tRNA m6t6A37 methyltransferase activity
H4B47_12370	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H4B47_12385	COG0642	Histidine kinase
H4B47_12395	COG0494	nUDIX hydrolase
H4B47_12405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H4B47_12410	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H4B47_12415	COG3139	Protein of unknown function (DUF1315)
H4B47_12420	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H4B47_12425	COG1301	dicarboxylic acid transport
H4B47_12430	COG1960	acyl-CoA dehydrogenase activity
H4B47_12435	COG2819	hydrolase of the alpha beta superfamily
H4B47_12445	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H4B47_12455	COG2195	Cleaves the N-terminal amino acid of tripeptides
H4B47_12460	COG1234	tRNA 3'-trailer cleavage
H4B47_12490	COG2363	Small membrane protein
H4B47_12510	COG0513	Belongs to the DEAD box helicase family
H4B47_12520	COG0778	Nitroreductase
H4B47_12550	COG1286	toxin biosynthetic process
H4B47_12575	COG4783	chaperone-mediated protein folding
H4B47_12580	COG1610	YqeY-like protein
H4B47_12610	COG2815	serine threonine protein kinase
H4B47_12610	COG0515	serine threonine protein kinase
H4B47_12635	COG2831	hemolysin activation secretion protein
H4B47_12720	COG3111	PFAM Bacterial OB fold (BOF) protein
H4B47_12745	COG3243	poly(R)-hydroxyalkanoic acid synthase
H4B47_12750	COG0786	glutamate:sodium symporter activity
H4B47_12760	COG2186	Transcriptional regulator
H4B47_12805	COG0477	Major facilitator Superfamily
H4B47_12810	COG1051	belongs to the nudix hydrolase family
H4B47_12840	COG2995	paraquat-inducible protein a
H4B47_12845	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H4B47_12845	COG3008	intermembrane lipid transfer
H4B47_12855	COG1794	racemase activity, acting on amino acids and derivatives
H4B47_12890	COG1301	dicarboxylic acid transport
H4B47_12900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H4B47_12905	COG2011	ABC-type metal ion transport system permease component
H4B47_12910	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H4B47_12915	COG1464	Belongs to the NlpA lipoprotein family
H4B47_12920	COG0151	Belongs to the GarS family
H4B47_12925	COG0138	bifunctional purine biosynthesis protein purh
H4B47_12930	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H4B47_12960	COG2308	Evidence 4 Homologs of previously reported genes of
H4B47_12970	COG1305	Transglutaminase-like
H4B47_12980	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H4B47_12985	COG0305	Participates in initiation and elongation during chromosome replication
H4B47_13010	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H4B47_13020	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H4B47_13025	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H4B47_13050	COG1649	PFAM Uncharacterised BCR, COG1649
H4B47_13050	COG0726	polysaccharide deacetylase
H4B47_13055	COG1215	transferase activity, transferring glycosyl groups
H4B47_13060	COG3658	cytochrome
H4B47_13070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H4B47_13085	COG0583	DNA-binding transcription factor activity
H4B47_13115	COG1960	acyl-CoA dehydrogenase activity
H4B47_13120	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H4B47_13125	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H4B47_13140	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H4B47_13150	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H4B47_13155	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H4B47_13170	COG0745	RESPONSE REGULATOR receiver
H4B47_13175	COG0174	glutamine synthetase
H4B47_13195	COG0729	surface antigen
H4B47_13220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H4B47_13225	COG2814	Major facilitator Superfamily
H4B47_13240	COG0583	DNA-binding transcription factor activity
H4B47_13255	COG1187	pseudouridine synthase activity
H4B47_13275	COG0802	atpase or kinase
H4B47_13280	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H4B47_13290	COG1923	regulation of RNA biosynthetic process
H4B47_13295	COG0697	spore germination
H4B47_13310	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H4B47_13320	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H4B47_13325	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H4B47_13325	COG0519	Catalyzes the synthesis of GMP from XMP
H4B47_13330	COG4302	ethanolamine ammonia-lyase activity
H4B47_13335	COG4303	Ethanolamine ammonia lyase large subunit
H4B47_13340	COG0531	amino acid
H4B47_13360	COG1454	alcohol dehydrogenase
H4B47_13365	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H4B47_13375	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H4B47_13395	COG0308	aminopeptidase N
H4B47_13435	COG1605	Chorismate mutase
H4B47_13450	COG1309	transcriptional regulator
H4B47_13460	COG0668	transmembrane transport
H4B47_13485	COG4773	Receptor
H4B47_13505	COG0488	(ABC) transporter
H4B47_13510	COG0589	response to stress
H4B47_13535	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H4B47_13545	COG3135	benzoate transporter
H4B47_13550	COG1522	sequence-specific DNA binding
H4B47_13560	COG2963	transposase activity
H4B47_13580	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H4B47_13585	COG0583	DNA-binding transcription factor activity
H4B47_13595	COG0183	Belongs to the thiolase family
H4B47_13605	COG2030	dehydratase
H4B47_13610	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H4B47_13625	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H4B47_13640	COG0824	Thioesterase
H4B47_13645	COG1454	alcohol dehydrogenase
H4B47_13655	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H4B47_13675	COG0069	glutamate synthase activity
H4B47_13725	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H4B47_14015	COG2026	Addiction module toxin, RelE StbE family
H4B47_14055	COG0592	DNA-directed DNA polymerase activity
H4B47_14100	COG2963	transposase activity
H4B47_14190	COG2814	Major facilitator Superfamily
H4B47_14205	COG0511	ligase activity, forming carbon-carbon bonds
H4B47_14220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H4B47_14220	COG1116	anion transmembrane transporter activity
H4B47_14225	COG0745	RESPONSE REGULATOR receiver
H4B47_14235	COG2146	nitrite reductase [NAD(P)H] activity
H4B47_14235	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H4B47_14240	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H4B47_14245	COG0243	molybdopterin cofactor binding
H4B47_14255	COG0243	molybdopterin cofactor binding
H4B47_14260	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H4B47_14275	COG0315	cyclic pyranopterin monophosphate synthase activity
H4B47_14275	COG0521	Mo-molybdopterin cofactor biosynthetic process
H4B47_14280	COG0303	'Molybdopterin
H4B47_14290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H4B47_14295	COG0697	spore germination
H4B47_14315	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H4B47_14320	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H4B47_14375	COG2204	response regulator
H4B47_14380	COG3852	Histidine kinase
H4B47_14405	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H4B47_14410	COG0575	Belongs to the CDS family
H4B47_14445	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H4B47_14460	COG2137	regulation of response to DNA damage stimulus
H4B47_14470	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H4B47_14475	COG1011	Hydrolase
H4B47_14510	COG1113	amino acid transport
H4B47_14530	COG0659	secondary active sulfate transmembrane transporter activity
H4B47_14535	COG2135	peptidase activity
H4B47_14550	COG3300	MHYT domain
H4B47_14550	COG5001	Diguanylate cyclase
H4B47_14565	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H4B47_14565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H4B47_14565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H4B47_14570	COG1105	Belongs to the carbohydrate kinase PfkB family
H4B47_14575	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H4B47_14575	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H4B47_14605	COG0024	Methionine aminopeptidase
H4B47_14610	COG0583	DNA-binding transcription factor activity
H4B47_14620	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H4B47_14625	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H4B47_14630	COG0516	GMP reductase activity
H4B47_14630	COG0517	IMP dehydrogenase activity
H4B47_14655	COG0552	protein localization to endoplasmic reticulum
H4B47_14665	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
H4B47_14675	COG4890	Cyd operon protein YbgT
H4B47_14680	COG1294	oxidase, subunit
H4B47_14695	COG1585	Membrane protein implicated in regulation of membrane protease activity
H4B47_14705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H4B47_14710	COG4774	siderophore transport
H4B47_14725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H4B47_14730	COG0569	domain protein
H4B47_14735	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H4B47_14765	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H4B47_14770	COG0542	response to heat
H4B47_14795	COG0446	pyridine nucleotide-disulphide oxidoreductase
H4B47_14795	COG1902	pentaerythritol trinitrate reductase activity
H4B47_14840	COG2323	membrane
H4B47_14845	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H4B47_14855	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H4B47_14860	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H4B47_14865	COG0183	Belongs to the thiolase family
H4B47_14870	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H4B47_14875	COG0596	Alpha beta hydrolase
H4B47_14880	COG2271	Major facilitator Superfamily
H4B47_14885	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H4B47_14890	COG3485	protocatechuate 3,4-dioxygenase
H4B47_14895	COG3485	protocatechuate 3,4-dioxygenase
H4B47_14900	COG0710	3-dehydroquinate dehydratase activity
H4B47_14905	COG3420	alginic acid biosynthetic process
H4B47_14910	COG3659	wide pore channel activity
H4B47_14915	COG4993	Dehydrogenase
H4B47_14925	COG2391	methyltransferase activity
H4B47_14940	COG1414	Transcriptional regulator
H4B47_14945	COG0583	DNA-binding transcription factor activity
H4B47_14975	COG2814	Major facilitator Superfamily
H4B47_14985	COG0154	amidase activity
H4B47_15005	COG4638	Rieske (2fe-2S)
H4B47_15015	COG1028	Short-chain dehydrogenase reductase Sdr
H4B47_15025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H4B47_15035	COG3733	amine oxidase
H4B47_15045	COG1012	belongs to the aldehyde dehydrogenase family
H4B47_15055	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H4B47_15060	COG0183	Belongs to the thiolase family
H4B47_15065	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H4B47_15070	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H4B47_15080	COG4829	muconolactone delta-isomerase
H4B47_15085	COG4948	Mandelate Racemase Muconate Lactonizing
H4B47_15090	COG0583	DNA-binding transcription factor activity
H4B47_15100	COG2186	Transcriptional regulator
H4B47_15135	COG0446	pyridine nucleotide-disulphide oxidoreductase
H4B47_15135	COG1902	pentaerythritol trinitrate reductase activity
H4B47_15175	COG1309	transcriptional regulator
H4B47_15185	COG1335	isochorismatase
H4B47_15190	COG0583	DNA-binding transcription factor activity
H4B47_15210	COG1473	amidohydrolase
H4B47_15225	COG4191	Histidine kinase
H4B47_15260	COG2188	Transcriptional regulator
H4B47_15275	COG0583	DNA-binding transcription factor activity
H4B47_15300	COG1566	PFAM secretion protein HlyD family protein
H4B47_15320	COG0129	dihydroxy-acid dehydratase activity
H4B47_15330	COG0583	DNA-binding transcription factor activity
H4B47_15335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H4B47_15345	COG2084	Dehydrogenase
H4B47_15350	COG2207	Transcriptional regulator
H4B47_15365	COG1064	alcohol dehydrogenase
H4B47_15375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H4B47_15380	COG1120	ATPase activity
H4B47_15400	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H4B47_15450	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H4B47_15485	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H4B47_15535	COG0583	DNA-binding transcription factor activity
H4B47_15540	COG1414	Transcriptional regulator
H4B47_15545	COG2851	Citrate transporter
H4B47_15550	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H4B47_15555	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H4B47_15560	COG1028	Short-chain dehydrogenase reductase Sdr
H4B47_15575	COG2207	Transcriptional regulator
H4B47_15585	COG2205	protein histidine kinase activity
H4B47_15590	COG0745	RESPONSE REGULATOR receiver
H4B47_15595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H4B47_15600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H4B47_15615	COG3539	Fimbrial protein
H4B47_15640	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H4B47_15650	COG0753	catalase activity
H4B47_15670	COG2963	transposase activity
H4B47_15680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H4B47_15745	COG3433	isochorismatase activity
H4B47_15745	COG1535	isochorismatase
H4B47_15750	COG1028	Short-chain dehydrogenase reductase Sdr
H4B47_15755	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H4B47_15760	COG4149	molybdate abc transporter
H4B47_15765	COG0725	ABC transporter, periplasmic molybdate-binding protein
H4B47_15775	COG4638	Rieske (2fe-2S)
H4B47_15780	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H4B47_15785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H4B47_15785	COG0543	2 iron, 2 sulfur cluster binding
H4B47_15800	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H4B47_15810	COG1028	Short-chain dehydrogenase reductase Sdr
H4B47_15830	COG2963	transposase activity
H4B47_15845	COG2207	Transcriptional regulator
H4B47_15850	COG1028	Short-chain dehydrogenase reductase Sdr
H4B47_15855	COG2610	gluconate transmembrane transporter activity
H4B47_15865	COG1309	transcriptional regulator
H4B47_15885	COG0583	DNA-binding transcription factor activity
H4B47_15900	COG2031	fatty acid transporter
H4B47_15905	COG0183	Belongs to the thiolase family
H4B47_15910	COG0583	DNA-binding transcription factor activity
H4B47_15915	COG0583	DNA-binding transcription factor activity
H4B47_15930	COG1027	Aspartate ammonia-lyase
H4B47_15940	COG0477	Major facilitator Superfamily
H4B47_15965	COG4521	taurine ABC transporter
H4B47_15980	COG2188	Transcriptional regulator
H4B47_15990	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H4B47_15995	COG1733	regulation of RNA biosynthetic process
H4B47_16000	COG3708	Transcriptional regulator
H4B47_16000	COG2207	Transcriptional regulator
H4B47_16015	COG0730	response to heat
H4B47_16025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H4B47_16025	COG3453	Protein conserved in bacteria
H4B47_16035	COG3781	membrane
H4B47_16040	COG1063	alcohol dehydrogenase
H4B47_16050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H4B47_16055	COG0508	dehydrogenase complex catalyzes the overall conversion of
H4B47_16060	COG0022	dehydrogenase e1 component
H4B47_16065	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H4B47_16070	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H4B47_16100	COG0133	tryptophan synthase activity
H4B47_16110	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H4B47_16145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H4B47_16170	COG2226	methyltransferase
H4B47_16225	COG0842	Transport permease protein
H4B47_16230	COG0842	Transport permease protein
H4B47_16235	COG1131	(ABC) transporter
H4B47_16250	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H4B47_16255	COG4773	Receptor
H4B47_16275	COG0730	response to heat
H4B47_16280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H4B47_16300	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
H4B47_16315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H4B47_16345	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H4B47_16355	COG4264	IucA IucC family
H4B47_16380	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H4B47_16395	COG1960	acyl-CoA dehydrogenase activity
H4B47_16400	COG1960	acyl-CoA dehydrogenase activity
H4B47_16405	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H4B47_16410	COG2207	Transcriptional regulator
H4B47_16415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H4B47_16420	COG0776	regulation of translation
H4B47_16445	COG0822	iron-sulfur transferase activity
H4B47_16450	COG0316	Belongs to the HesB IscA family
H4B47_16480	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H4B47_16500	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H4B47_16505	COG0702	epimerase
H4B47_16540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H4B47_16600	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H4B47_16675	COG0739	heme binding
H4B47_16675	COG0741	lytic transglycosylase activity
H4B47_16675	COG1196	nuclear chromosome segregation
H4B47_16815	COG0305	Participates in initiation and elongation during chromosome replication
H4B47_16830	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H4B47_16875	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H4B47_16905	COG0776	regulation of translation
H4B47_16970	COG0084	hydrolase, TatD family'
H4B47_16990	COG1663	tetraacyldisaccharide 4'-kinase activity
H4B47_16995	COG1132	(ABC) transporter
H4B47_17005	COG0811	peptide transport
H4B47_17010	COG1475	DNA binding
H4B47_17015	COG1192	Involved in chromosome partitioning
H4B47_17025	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H4B47_17040	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H4B47_17045	COG0191	fructose-bisphosphate aldolase activity
H4B47_17065	COG0424	maF-like protein
H4B47_17070	COG2850	peptidyl-arginine hydroxylation
H4B47_17080	COG0640	Transcriptional regulator
H4B47_17090	COG3619	membrane
H4B47_17095	COG3122	Protein conserved in bacteria
H4B47_17100	COG1132	(ABC) transporter
H4B47_17120	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H4B47_17135	COG2963	transposase activity
H4B47_17140	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H4B47_17150	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H4B47_17150	COG0506	proline dehydrogenase activity
H4B47_17150	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H4B47_17155	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H4B47_17180	COG2353	YceI-like domain
H4B47_17190	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H4B47_17235	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H4B47_17235	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H4B47_17260	COG3539	Fimbrial protein
H4B47_17265	COG3121	Chaperone
H4B47_17295	COG0697	spore germination
H4B47_17305	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H4B47_17315	COG0583	DNA-binding transcription factor activity
H4B47_17335	COG1309	transcriptional regulator
H4B47_17350	COG1522	sequence-specific DNA binding
H4B47_17360	COG1126	abc transporter atp-binding protein
H4B47_17365	COG0765	amino acid transport
H4B47_17370	COG0765	amino acid transport
H4B47_17400	COG1464	Belongs to the NlpA lipoprotein family
H4B47_17410	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H4B47_17415	COG2011	ABC-type metal ion transport system permease component
H4B47_17420	COG0012	GTP binding
H4B47_17445	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H4B47_17480	COG2963	transposase activity
H4B47_17505	COG0386	Belongs to the glutathione peroxidase family
H4B47_17515	COG0436	Aminotransferase
H4B47_17555	COG3634	alkyl hydroperoxide reductase activity
H4B47_17570	COG0583	DNA-binding transcription factor activity
H4B47_17575	COG0798	PFAM Bile acid sodium symporter
H4B47_17580	COG0640	Transcriptional regulator
H4B47_17595	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H4B47_17605	COG0583	DNA-binding transcription factor activity
H4B47_17615	COG1953	Uracil, thiamine, allantoin
H4B47_17625	COG2175	clavaminate synthase activity
H4B47_17630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H4B47_17635	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H4B47_17640	COG4521	taurine ABC transporter
H4B47_17650	COG0477	Major facilitator Superfamily
H4B47_17670	COG1271	oxidase subunit
H4B47_17675	COG1294	oxidase, subunit
H4B47_17685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H4B47_17705	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H4B47_17725	COG3052	prosthetic group binding
H4B47_17730	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
H4B47_17740	COG0583	DNA-binding transcription factor activity
H4B47_17750	COG2814	Major facilitator Superfamily
H4B47_17770	COG1346	cytolysis
H4B47_17780	COG0583	DNA-binding transcription factor activity
H4B47_17785	COG0625	glutathione transferase activity
H4B47_17790	COG0625	glutathione transferase activity
H4B47_17795	COG0583	DNA-binding transcription factor activity
H4B47_17810	COG1045	serine acetyltransferase
H4B47_17815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H4B47_17820	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H4B47_17825	COG1280	lysine exporter protein (LysE YggA)
H4B47_17840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H4B47_17845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H4B47_17850	COG1126	abc transporter atp-binding protein
H4B47_17855	COG0765	amino acid transport
H4B47_17860	COG0765	amino acid transport
H4B47_17880	COG0784	Response regulator, receiver
H4B47_17880	COG2205	protein histidine kinase activity
H4B47_17900	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H4B47_17920	COG1028	Short-chain dehydrogenase reductase Sdr
H4B47_17970	COG0583	DNA-binding transcription factor activity
H4B47_17990	COG0318	PFAM AMP-dependent synthetase and ligase
H4B47_17995	COG1309	transcriptional regulator
H4B47_18000	COG1960	acyl-CoA dehydrogenase activity
H4B47_18005	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H4B47_18010	COG1024	Enoyl-CoA hydratase
H4B47_18015	COG4770	biotin carboxylase activity
H4B47_18025	COG0583	DNA-binding transcription factor activity
H4B47_18040	COG1960	acyl-CoA dehydrogenase activity
H4B47_18050	COG2814	Major facilitator Superfamily
H4B47_18060	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H4B47_18065	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H4B47_18070	COG2814	Major facilitator Superfamily
H4B47_18075	COG1960	acyl-CoA dehydrogenase activity
H4B47_18080	COG1024	Enoyl-CoA hydratase
H4B47_18085	COG1028	Short-chain dehydrogenase reductase Sdr
H4B47_18090	COG1250	3-hydroxyacyl-CoA dehydrogenase
H4B47_18095	COG0183	Belongs to the thiolase family
H4B47_18105	COG2814	Major facilitator Superfamily
H4B47_18115	COG1024	Enoyl-CoA hydratase
H4B47_18125	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H4B47_18130	COG1960	acyl-CoA dehydrogenase activity
H4B47_18135	COG2814	Major facilitator Superfamily
H4B47_18140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H4B47_18145	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H4B47_18160	COG3842	ATPase activity
H4B47_18165	COG1840	ABC-type Fe3 transport system, periplasmic component
H4B47_18175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H4B47_18180	COG1414	Transcriptional regulator
H4B47_18190	COG0583	DNA-binding transcription factor activity
H4B47_18195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H4B47_18200	COG1012	belongs to the aldehyde dehydrogenase family
H4B47_18210	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H4B47_18225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H4B47_18230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H4B47_18235	COG2267	carboxylic ester hydrolase activity
H4B47_18255	COG3038	cytochrome b561
H4B47_18260	COG0753	catalase activity
H4B47_18285	COG2050	protein possibly involved in aromatic compounds catabolism
H4B47_18295	COG3327	negative regulation of DNA-templated transcription, initiation
H4B47_18300	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
H4B47_18305	COG0183	Belongs to the thiolase family
H4B47_18310	COG1250	3-hydroxyacyl-CoA dehydrogenase
H4B47_18315	COG1024	Enoyl-CoA hydratase
H4B47_18320	COG1024	Enoyl-CoA hydratase
H4B47_18325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H4B47_18330	COG2151	metal-sulfur cluster biosynthetic enzyme
H4B47_18335	COG3396	Phenylacetate-CoA oxygenase
H4B47_18340	COG3460	Phenylacetate-CoA oxygenase
H4B47_18345	COG3396	Phenylacetate-CoA oxygenase
H4B47_18350	COG1012	belongs to the aldehyde dehydrogenase family
H4B47_18350	COG2030	dehydratase
H4B47_18355	COG1760	l-serine dehydratase
H4B47_18360	COG0531	amino acid
H4B47_18365	COG1012	belongs to the aldehyde dehydrogenase family
H4B47_18390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H4B47_18410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H4B47_18420	COG0789	Transcriptional regulator
H4B47_18430	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H4B47_18445	COG2807	transmembrane transport
H4B47_18450	COG0590	tRNA wobble adenosine to inosine editing
H4B47_18565	COG1116	anion transmembrane transporter activity
H4B47_18570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H4B47_18580	COG0864	Transcriptional regulator
H4B47_18595	COG1733	regulation of RNA biosynthetic process
H4B47_18600	COG2249	NAD(P)H dehydrogenase (quinone) activity
H4B47_18605	COG0439	Biotin carboxylase
H4B47_18620	COG1063	alcohol dehydrogenase
H4B47_18645	COG3210	domain, Protein
H4B47_18650	COG2831	hemolysin activation secretion protein
H4B47_18655	COG0038	chloride channel
H4B47_18660	COG4770	biotin carboxylase activity
H4B47_18680	COG1914	H( )-stimulated, divalent metal cation uptake system
H4B47_18685	COG0583	DNA-binding transcription factor activity
H4B47_18705	COG1011	Hydrolase
H4B47_18725	COG1250	3-hydroxyacyl-CoA dehydrogenase
H4B47_18745	COG2814	Major facilitator Superfamily
H4B47_18755	COG1560	Kdo2-lipid A biosynthetic process
H4B47_18770	COG1522	sequence-specific DNA binding
H4B47_18785	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H4B47_18795	COG4122	O-methyltransferase activity
H4B47_18825	COG1538	Outer membrane efflux protein
H4B47_18830	COG1137	ATPase activity
H4B47_18835	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H4B47_18845	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H4B47_18885	COG2814	Major facilitator Superfamily
H4B47_18920	COG1278	Cold shock
H4B47_18955	COG1570	exodeoxyribonuclease VII activity
H4B47_19005	COG0583	DNA-binding transcription factor activity
H4B47_19010	COG4638	Rieske (2fe-2S)
H4B47_19015	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H4B47_19020	COG0633	Ferredoxin
H4B47_19020	COG0543	2 iron, 2 sulfur cluster binding
H4B47_19025	COG1028	Short-chain dehydrogenase reductase Sdr
H4B47_19030	COG3135	benzoate transporter
H4B47_19035	COG2814	Major facilitator Superfamily
H4B47_19050	COG1643	Atp-dependent helicase
H4B47_19055	COG0450	alkyl hydroperoxide reductase
H4B47_19065	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H4B47_19075	COG3634	alkyl hydroperoxide reductase activity
H4B47_19095	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H4B47_19100	COG0625	glutathione transferase activity
H4B47_19110	COG2885	chlorophyll binding
H4B47_19145	COG0542	response to heat
H4B47_19160	COG1765	OsmC-like protein
H4B47_19170	COG0667	Aldo Keto reductase
H4B47_19185	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H4B47_19200	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H4B47_19210	COG0527	aspartate kinase activity
H4B47_19220	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H4B47_19230	COG3038	cytochrome b561
H4B47_19235	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H4B47_19240	COG2252	PERMEase
H4B47_19250	COG2072	flavoprotein involved in K transport
H4B47_19265	COG1741	Belongs to the pirin family
H4B47_19280	COG0300	oxidoreductase activity
H4B47_19285	COG2072	flavoprotein involved in K transport
H4B47_19290	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
H4B47_19335	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H4B47_19350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H4B47_19365	COG2814	Major facilitator Superfamily
H4B47_19370	COG1024	Enoyl-CoA hydratase
H4B47_19375	COG1012	belongs to the aldehyde dehydrogenase family
H4B47_19385	COG1960	acyl-CoA dehydrogenase activity
H4B47_19410	COG2186	Transcriptional regulator
H4B47_19415	COG1012	belongs to the aldehyde dehydrogenase family
H4B47_19425	COG4948	Mandelate Racemase Muconate Lactonizing
H4B47_19430	COG2271	Major facilitator Superfamily
H4B47_19435	COG2721	sulfolactate sulfo-lyase activity
H4B47_19440	COG0697	spore germination
H4B47_19475	COG1012	belongs to the aldehyde dehydrogenase family
H4B47_19495	COG0531	amino acid
H4B47_19505	COG1113	amino acid transport
H4B47_19550	COG4269	membrane
H4B47_19565	COG0446	pyridine nucleotide-disulphide oxidoreductase
H4B47_19565	COG1902	pentaerythritol trinitrate reductase activity
H4B47_19575	COG5001	Diguanylate cyclase
H4B47_19575	COG4251	negative regulation of phosphorylation
H4B47_19575	COG3706	GGDEF domain
H4B47_19575	COG2203	Gaf domain
H4B47_19585	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H4B47_19610	COG4239	(ABC) transporter, permease
H4B47_19615	COG4174	ABC transporter (Permease)
H4B47_19625	COG0741	lytic transglycosylase activity
H4B47_19625	COG1388	LysM domain
H4B47_19625	COG1388	LysM domain
H4B47_19625	COG0741	lytic transglycosylase activity
H4B47_19630	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H4B47_19670	COG0583	DNA-binding transcription factor activity
H4B47_19675	COG1279	arginine transmembrane transporter activity
H4B47_19695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H4B47_19700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H4B47_19705	COG0006	proline dipeptidase activity
H4B47_19735	COG2963	transposase activity