locus-tag	class	description
LX00_00010	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LX00_00015	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LX00_00020	COG0596	Alpha beta hydrolase
LX00_00045	COG0488	(ABC) transporter
LX00_00050	COG0586	Pfam SNARE associated Golgi protein
LX00_00060	COG0187	DNA topoisomerase II activity
LX00_00070	COG0592	DNA-directed DNA polymerase activity
LX00_00080	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LX00_00095	COG0706	membrane insertase activity
LX00_00110	COG1230	cation diffusion facilitator family transporter
LX00_00115	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LX00_00135	COG0402	S-adenosylhomocysteine deaminase activity
LX00_00145	COG0754	glutathionylspermidine amidase activity
LX00_00155	COG0861	Integral membrane protein TerC family
LX00_00160	COG0671	phosphoesterase, PA-phosphatase related
LX00_00170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LX00_00185	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LX00_00190	COG2951	lytic endotransglycosylase activity
LX00_00220	COG0583	DNA-binding transcription factor activity
LX00_00245	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LX00_00285	COG1047	Peptidyl-prolyl cis-trans
LX00_00295	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LX00_00300	COG0196	riboflavin kinase activity
LX00_00310	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LX00_00315	COG1309	transcriptional regulator
LX00_00320	COG1116	anion transmembrane transporter activity
LX00_00325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LX00_00330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LX00_00335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LX00_00340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LX00_00360	COG1028	Short-chain dehydrogenase reductase Sdr
LX00_00365	COG0546	phosphoglycolate phosphatase activity
LX00_00425	COG3023	N-Acetylmuramoyl-L-alanine amidase
LX00_00430	COG0728	peptidoglycan biosynthetic process
LX00_00460	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LX00_00490	COG0438	transferase activity, transferring glycosyl groups
LX00_00515	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LX00_00520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LX00_00535	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LX00_00540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LX00_00550	COG2186	Transcriptional regulator
LX00_00560	COG0277	FAD linked oxidase domain protein
LX00_00565	COG1448	Aminotransferase
LX00_00570	COG1802	Transcriptional regulator
LX00_00585	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LX00_00620	COG0564	pseudouridine synthase activity
LX00_00645	COG1522	sequence-specific DNA binding
LX00_00660	COG0251	oxidation-reduction process
LX00_00665	COG1113	amino acid transport
LX00_00670	COG1113	amino acid transport
LX00_00690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LX00_00695	COG1960	acyl-CoA dehydrogenase activity
LX00_00700	COG1024	Enoyl-CoA hydratase
LX00_00705	COG1024	Enoyl-CoA hydratase
LX00_00710	COG0477	Major facilitator Superfamily
LX00_00715	COG3916	Acyl-homoserine-lactone synthase
LX00_00725	COG2197	response regulator
LX00_00735	COG1960	acyl-CoA dehydrogenase activity
LX00_00740	COG3321	synthase
LX00_00740	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LX00_00740	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LX00_00740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LX00_00780	COG0271	Belongs to the BolA IbaG family
LX00_00790	COG1192	Involved in chromosome partitioning
LX00_00805	COG0586	Pfam SNARE associated Golgi protein
LX00_00810	COG2259	Doxx family
LX00_00815	COG4399	Belongs to the UPF0754 family
LX00_00820	COG0519	Catalyzes the synthesis of GMP from XMP
LX00_00820	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LX00_00865	COG0281	malic enzyme
LX00_00870	COG2837	iron assimilation
LX00_00875	COG1280	lysine exporter protein (LysE YggA)
LX00_00880	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LX00_00885	COG1121	(ABC) transporter
LX00_00950	COG0386	Belongs to the glutathione peroxidase family
LX00_00965	COG1309	transcriptional regulator
LX00_00970	COG0697	spore germination
LX00_00980	COG0758	DNA mediated transformation
LX00_01015	COG1309	transcriptional regulator
LX00_01050	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LX00_01060	COG0655	NAD(P)H dehydrogenase (quinone) activity
LX00_01095	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LX00_01105	COG2814	Major facilitator Superfamily
LX00_01115	COG1253	flavin adenine dinucleotide binding
LX00_01120	COG3012	SEC-C Motif Domain Protein
LX00_01125	COG2860	membrane
LX00_01130	COG0477	Major facilitator Superfamily
LX00_01140	COG0318	PFAM AMP-dependent synthetase and ligase
LX00_01155	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LX00_01170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LX00_01180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LX00_01185	COG0606	chelatase, subunit chli
LX00_01195	COG0347	Belongs to the P(II) protein family
LX00_01200	COG0004	ammonium transporteR
LX00_01210	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LX00_01210	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LX00_01250	COG0795	lipopolysaccharide-transporting ATPase activity
LX00_01255	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LX00_01260	COG0793	Belongs to the peptidase S41A family
LX00_01275	COG2197	response regulator
LX00_01285	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LX00_01295	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LX00_01300	COG4974	Belongs to the 'phage' integrase family
LX00_01325	COG0772	Belongs to the SEDS family
LX00_01330	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LX00_01335	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LX00_01340	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LX00_01365	COG0697	spore germination
LX00_01370	COG1538	Outer membrane efflux protein
LX00_01390	COG3275	phosphorelay sensor kinase activity
LX00_01400	COG0181	hydroxymethylbilane synthase activity
LX00_01445	COG1716	ATPase activity
LX00_01450	COG0546	phosphoglycolate phosphatase activity
LX00_01550	COG0596	Alpha beta hydrolase
LX00_01555	COG2056	Na+-H+ antiporter family
LX00_01570	COG0326	Molecular chaperone. Has ATPase activity
LX00_01585	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LX00_01650	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LX00_01655	COG2169	Transcriptional regulator
LX00_01655	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LX00_01685	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LX00_01695	COG0497	DNA recombination
LX00_01710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LX00_01720	COG0237	dephospho-CoA kinase activity
LX00_01775	COG0195	Participates in both transcription termination and antitermination
LX00_01795	COG2212	antiporter activity
LX00_01805	COG0651	ATP synthesis coupled electron transport
LX00_01810	COG1006	Multisubunit Na H antiporter MnhC subunit
LX00_01815	COG2111	Na H antiporter
LX00_01815	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LX00_01830	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LX00_01840	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LX00_01850	COG2226	methyltransferase
LX00_01870	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LX00_01875	COG1074	ATP-dependent DNA helicase activity
LX00_01880	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LX00_01900	COG0598	Magnesium transport protein CorA
LX00_01905	COG0789	Transcriptional regulator
LX00_01910	COG0484	heat shock protein binding
LX00_01925	COG0475	glutathione-regulated potassium exporter activity
LX00_01925	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LX00_01930	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LX00_01950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LX00_01960	COG4535	Mg2 and Co2 transporter CorC
LX00_01965	COG0425	Belongs to the sulfur carrier protein TusA family
LX00_01970	COG0644	oxidoreductase
LX00_01970	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
LX00_01980	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LX00_01995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LX00_02000	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LX00_02035	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LX00_02050	COG0534	Mate efflux family protein
LX00_02060	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LX00_02065	COG1028	Short-chain dehydrogenase reductase Sdr
LX00_02070	COG0583	DNA-binding transcription factor activity
LX00_02085	COG1530	ribonuclease E activity
LX00_02095	COG0546	phosphoglycolate phosphatase activity
LX00_02100	COG2378	regulation of single-species biofilm formation
LX00_02105	COG0625	glutathione transferase activity
LX00_02115	COG0583	DNA-binding transcription factor activity
LX00_02180	COG0473	3-isopropylmalate dehydrogenase activity
LX00_02235	COG1301	dicarboxylic acid transport
LX00_02245	COG1560	Kdo2-lipid A biosynthetic process
LX00_02250	COG1280	lysine exporter protein (LysE YggA)
LX00_02270	COG1733	regulation of RNA biosynthetic process
LX00_02295	COG0210	DNA helicase
LX00_02300	COG0724	RNA recognition motif
LX00_02320	COG4651	solute:proton antiporter activity
LX00_02320	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LX00_02325	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LX00_02330	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LX00_02345	COG0788	formyltetrahydrofolate deformylase activity
LX00_02445	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LX00_02445	COG2813	Specifically methylates the guanine in position
LX00_02455	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LX00_02465	COG4774	siderophore transport
LX00_02475	COG0740	serine-type endopeptidase activity
LX00_02495	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LX00_02495	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LX00_02500	COG0857	belongs to the CobB CobQ family
LX00_02500	COG0280	phosphate acetyltransferase
LX00_02505	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LX00_02520	COG0800	Aldolase
LX00_02530	COG3265	gluconokinase activity
LX00_02535	COG1012	belongs to the aldehyde dehydrogenase family
LX00_02545	COG2267	carboxylic ester hydrolase activity
LX00_02560	COG0793	Belongs to the peptidase S41A family
LX00_02595	COG1426	Protein conserved in bacteria
LX00_02635	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LX00_02645	COG1162	GTPase activity
LX00_02650	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LX00_02665	COG1538	Outer membrane efflux protein
LX00_02670	COG1136	(ABC) transporter
LX00_02670	COG0577	efflux transmembrane transporter activity
LX00_02675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LX00_02700	COG0028	Belongs to the TPP enzyme family
LX00_02705	COG0440	acetolactate synthase activity
LX00_02735	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LX00_02750	COG0084	hydrolase, TatD family'
LX00_02765	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LX00_02770	COG0583	DNA-binding transcription factor activity
LX00_02780	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LX00_02785	COG2814	Major facilitator Superfamily
LX00_02795	COG0697	spore germination
LX00_02800	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LX00_02805	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LX00_02810	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LX00_02825	COG3622	Belongs to the hyi family
LX00_02830	COG2084	Dehydrogenase
LX00_02835	COG1024	Enoyl-CoA hydratase
LX00_02840	COG0784	Response regulator, receiver
LX00_02840	COG5002	protein histidine kinase activity
LX00_02840	COG2205	protein histidine kinase activity
LX00_02860	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LX00_02870	COG3956	TIGRFAM MazG family protein
LX00_02875	COG1555	photosystem II stabilization
LX00_02880	COG0617	tRNA 3'-terminal CCA addition
LX00_02885	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LX00_02905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LX00_02910	COG3028	Belongs to the UPF0307 family
LX00_02915	COG0318	PFAM AMP-dependent synthetase and ligase
LX00_02930	COG0625	glutathione transferase activity
LX00_02935	COG1238	metal cluster binding
LX00_02950	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LX00_02970	COG0072	phenylalanine-tRNA ligase activity
LX00_02995	COG0248	Ppx GppA phosphatase
LX00_03005	COG0037	tRNA processing
LX00_03045	COG1764	response to oxidative stress
LX00_03050	COG1846	Transcriptional regulator
LX00_03060	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LX00_03120	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LX00_03125	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LX00_03130	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LX00_03190	COG1214	PFAM Peptidase M22, glycoprotease
LX00_03205	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LX00_03215	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LX00_03220	COG0561	phosphatase activity
LX00_03230	COG2132	Multicopper oxidase
LX00_03250	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LX00_03255	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LX00_03260	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LX00_03290	COG1063	alcohol dehydrogenase
LX00_03295	COG0583	DNA-binding transcription factor activity
LX00_03300	COG1960	acyl-CoA dehydrogenase activity
LX00_03305	COG2814	Major facilitator Superfamily
LX00_03310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LX00_03320	COG1053	succinate dehydrogenase
LX00_03325	COG0583	DNA-binding transcription factor activity
LX00_03340	COG0583	DNA-binding transcription factor activity
LX00_03370	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LX00_03375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LX00_03430	COG0384	phenazine biosynthesis protein PhzF
LX00_03440	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LX00_03460	COG0745	RESPONSE REGULATOR receiver
LX00_03465	COG2205	protein histidine kinase activity
LX00_03500	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LX00_03530	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LX00_03535	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LX00_03555	COG0583	DNA-binding transcription factor activity
LX00_03575	COG0668	transmembrane transport
LX00_03585	COG2081	HI0933 family
LX00_03590	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LX00_03620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LX00_03620	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LX00_03630	COG0489	protein tyrosine kinase activity
LX00_03680	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LX00_03690	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LX00_03705	COG0730	response to heat
LX00_03715	COG1196	nuclear chromosome segregation
LX00_03735	COG2223	nitrite transmembrane transporter activity
LX00_03740	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
LX00_03745	COG1877	trehalose-phosphatase activity
LX00_03750	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LX00_03750	COG2226	methyltransferase
LX00_03750	COG0596	Alpha beta hydrolase
LX00_03765	COG4106	trans-aconitate 2-methyltransferase activity
LX00_03780	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LX00_03785	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LX00_03790	COG0009	L-threonylcarbamoyladenylate synthase
LX00_03795	COG3101	peptidyl-lysine hydroxylation
LX00_03800	COG1399	metal-binding, possibly nucleic acid-binding protein
LX00_03825	COG1652	LysM domain
LX00_03830	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LX00_03830	COG0352	thiamine-phosphate diphosphorylase activity
LX00_03830	COG0351	phosphomethylpyrimidine kinase
LX00_03840	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LX00_03870	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LX00_03895	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LX00_03910	COG0358	DNA primase activity
LX00_03920	COG0564	pseudouridine synthase activity
LX00_04010	COG0305	Participates in initiation and elongation during chromosome replication
LX00_04170	COG0741	lytic transglycosylase activity
LX00_04170	COG0739	heme binding
LX00_04170	COG1196	nuclear chromosome segregation
LX00_04220	COG0582	viral genome integration into host DNA
LX00_04230	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LX00_04245	COG0583	DNA-binding transcription factor activity
LX00_04250	COG0473	3-isopropylmalate dehydrogenase activity
LX00_04270	COG1012	belongs to the aldehyde dehydrogenase family
LX00_04290	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LX00_04290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LX00_04350	COG0456	acetyltransferase
LX00_04360	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LX00_04365	COG0492	ferredoxin-NADP+ reductase activity
LX00_04370	COG1674	ftsk spoiiie
LX00_04375	COG1280	lysine exporter protein (LysE YggA)
LX00_04390	COG2894	cell division
LX00_04405	COG0204	Acyl-transferase
LX00_04410	COG2885	chlorophyll binding
LX00_04415	COG0210	DNA helicase
LX00_04425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LX00_04440	COG0121	glutamine amidotransferase
LX00_04460	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LX00_04465	COG0735	belongs to the Fur family
LX00_04495	COG0420	3'-5' exonuclease activity
LX00_04515	COG1090	epimerase
LX00_04530	COG2050	protein possibly involved in aromatic compounds catabolism
LX00_04540	COG2814	Major facilitator Superfamily
LX00_04545	COG0405	Gamma-glutamyltransferase
LX00_04605	COG0477	Major facilitator Superfamily
LX00_04610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LX00_04635	COG0531	amino acid
LX00_04670	COG1309	transcriptional regulator
LX00_04675	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LX00_04680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LX00_04690	COG1607	acyl-coa hydrolase
LX00_04700	COG0523	cobalamin synthesis protein
LX00_04710	COG4681	YaeQ
LX00_04720	COG0726	polysaccharide deacetylase
LX00_04720	COG1649	PFAM Uncharacterised BCR, COG1649
LX00_04725	COG1215	transferase activity, transferring glycosyl groups
LX00_04735	COG1024	Enoyl-CoA hydratase
LX00_04750	COG1414	Transcriptional regulator
LX00_04770	COG1028	Short-chain dehydrogenase reductase Sdr
LX00_04785	COG2271	Major facilitator Superfamily
LX00_04795	COG2267	carboxylic ester hydrolase activity
LX00_04800	COG1028	Short-chain dehydrogenase reductase Sdr
LX00_04810	COG1012	belongs to the aldehyde dehydrogenase family
LX00_04815	COG0028	Belongs to the TPP enzyme family
LX00_04825	COG0477	Major facilitator Superfamily
LX00_04830	COG0242	peptide deformylase activity
LX00_04835	COG2066	Belongs to the glutaminase family
LX00_04840	COG2207	Transcriptional regulator
LX00_04845	COG2223	nitrite transmembrane transporter activity
LX00_04860	COG0583	DNA-binding transcription factor activity
LX00_04865	COG1028	Short-chain dehydrogenase reductase Sdr
LX00_04870	COG2271	Major facilitator Superfamily
LX00_04875	COG3959	Transketolase, thiamine diphosphate binding domain
LX00_04880	COG3958	Transketolase
LX00_04895	COG0306	phosphate transporter
LX00_04915	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LX00_04975	COG4181	ATPase activity
LX00_05005	COG0583	DNA-binding transcription factor activity
LX00_05015	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LX00_05020	COG1773	rubredoxin
LX00_05070	COG2851	Citrate transporter
LX00_05075	COG1253	flavin adenine dinucleotide binding
LX00_05125	COG0804	urea catabolic process
LX00_05135	COG0830	nickel cation binding
LX00_05150	COG0742	ribosomal rna small subunit methyltransferase
LX00_05155	COG0768	penicillin binding
LX00_05180	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LX00_05185	COG2878	Part of a membrane complex involved in electron transport
LX00_05190	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LX00_05200	COG3384	dioxygenase
LX00_05225	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LX00_05260	COG0006	proline dipeptidase activity
LX00_05265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LX00_05270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LX00_05290	COG1279	arginine transmembrane transporter activity
LX00_05295	COG0583	DNA-binding transcription factor activity
LX00_05335	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LX00_05340	COG1388	LysM domain
LX00_05340	COG0741	lytic transglycosylase activity
LX00_05340	COG1388	LysM domain
LX00_05340	COG0741	lytic transglycosylase activity
LX00_05350	COG4174	ABC transporter (Permease)
LX00_05355	COG4239	(ABC) transporter, permease
LX00_05360	COG4172	Belongs to the ABC transporter superfamily
LX00_05380	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LX00_05390	COG4251	negative regulation of phosphorylation
LX00_05390	COG3706	GGDEF domain
LX00_05390	COG2203	Gaf domain
LX00_05390	COG5001	Diguanylate cyclase
LX00_05400	COG1902	pentaerythritol trinitrate reductase activity
LX00_05400	COG0446	pyridine nucleotide-disulphide oxidoreductase
LX00_05455	COG3501	Rhs element vgr protein
LX00_05460	COG3209	COG3209 Rhs family protein
LX00_05500	COG1113	amino acid transport
LX00_05510	COG0531	amino acid
LX00_05535	COG1012	belongs to the aldehyde dehydrogenase family
LX00_05555	COG1113	amino acid transport
LX00_05575	COG0697	spore germination
LX00_05580	COG2721	sulfolactate sulfo-lyase activity
LX00_05585	COG2271	Major facilitator Superfamily
LX00_05590	COG4948	Mandelate Racemase Muconate Lactonizing
LX00_05600	COG1012	belongs to the aldehyde dehydrogenase family
LX00_05605	COG2186	Transcriptional regulator
LX00_05615	COG3316	Transposase and inactivated derivatives
LX00_05625	COG2252	PERMEase
LX00_05630	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LX00_05635	COG3038	cytochrome b561
LX00_05645	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LX00_05665	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LX00_05675	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LX00_05690	COG0667	Aldo Keto reductase
LX00_05700	COG1765	OsmC-like protein
LX00_05750	COG2885	chlorophyll binding
LX00_05760	COG0625	glutathione transferase activity
LX00_05765	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LX00_05785	COG3634	alkyl hydroperoxide reductase activity
LX00_05795	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LX00_05805	COG0450	alkyl hydroperoxide reductase
LX00_05810	COG1643	Atp-dependent helicase
LX00_05825	COG2814	Major facilitator Superfamily
LX00_05830	COG3135	benzoate transporter
LX00_05835	COG1028	Short-chain dehydrogenase reductase Sdr
LX00_05840	COG0543	2 iron, 2 sulfur cluster binding
LX00_05840	COG0633	Ferredoxin
LX00_05845	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
LX00_05850	COG4638	Rieske (2fe-2S)
LX00_05855	COG0583	DNA-binding transcription factor activity
LX00_05865	COG2871	sodium ion transport
LX00_05945	COG1570	exodeoxyribonuclease VII activity
LX00_05980	COG1280	lysine exporter protein (LysE YggA)
LX00_05985	COG1278	Cold shock
LX00_06015	COG2814	Major facilitator Superfamily
LX00_06020	COG1733	regulation of RNA biosynthetic process
LX00_06060	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LX00_06070	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LX00_06075	COG1137	ATPase activity
LX00_06080	COG1538	Outer membrane efflux protein
LX00_06120	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LX00_06145	COG1522	sequence-specific DNA binding
LX00_06150	COG5006	permease, DMT superfamily
LX00_06160	COG1560	Kdo2-lipid A biosynthetic process
LX00_06170	COG2814	Major facilitator Superfamily
LX00_06195	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LX00_06220	COG1250	3-hydroxyacyl-CoA dehydrogenase
LX00_06240	COG3501	Rhs element vgr protein
LX00_06280	COG0583	DNA-binding transcription factor activity
LX00_06285	COG1914	H( )-stimulated, divalent metal cation uptake system
LX00_06305	COG4770	biotin carboxylase activity
LX00_06310	COG0038	chloride channel
LX00_06335	COG1063	alcohol dehydrogenase
LX00_06350	COG0439	Biotin carboxylase
LX00_06355	COG2249	NAD(P)H dehydrogenase (quinone) activity
LX00_06360	COG1733	regulation of RNA biosynthetic process
LX00_06370	COG0864	Transcriptional regulator
LX00_06380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LX00_06385	COG1116	anion transmembrane transporter activity
LX00_06450	COG2885	chlorophyll binding
LX00_06450	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LX00_06490	COG0583	DNA-binding transcription factor activity
LX00_06500	COG0590	tRNA wobble adenosine to inosine editing
LX00_06505	COG2807	transmembrane transport
LX00_06520	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LX00_06530	COG0789	Transcriptional regulator
LX00_06545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LX00_06565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LX00_06590	COG1012	belongs to the aldehyde dehydrogenase family
LX00_06595	COG0531	amino acid
LX00_06600	COG1760	l-serine dehydratase
LX00_06605	COG1012	belongs to the aldehyde dehydrogenase family
LX00_06605	COG2030	dehydratase
LX00_06610	COG3396	Phenylacetate-CoA oxygenase
LX00_06615	COG3460	Phenylacetate-CoA oxygenase
LX00_06620	COG3396	Phenylacetate-CoA oxygenase
LX00_06625	COG2151	metal-sulfur cluster biosynthetic enzyme
LX00_06630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LX00_06635	COG1024	Enoyl-CoA hydratase
LX00_06640	COG1024	Enoyl-CoA hydratase
LX00_06645	COG1250	3-hydroxyacyl-CoA dehydrogenase
LX00_06650	COG0183	Belongs to the thiolase family
LX00_06655	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
LX00_06660	COG3327	negative regulation of DNA-templated transcription, initiation
LX00_06670	COG2050	protein possibly involved in aromatic compounds catabolism
LX00_06695	COG0753	catalase activity
LX00_06700	COG3038	cytochrome b561
LX00_06720	COG2267	carboxylic ester hydrolase activity
LX00_06725	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LX00_06730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LX00_06735	COG1012	belongs to the aldehyde dehydrogenase family
LX00_06745	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LX00_06755	COG1012	belongs to the aldehyde dehydrogenase family
LX00_06760	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LX00_06765	COG0583	DNA-binding transcription factor activity
LX00_06775	COG1414	Transcriptional regulator
LX00_06780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LX00_06790	COG1840	ABC-type Fe3 transport system, periplasmic component
LX00_06795	COG3842	ATPase activity
LX00_06810	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LX00_06815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LX00_06820	COG2814	Major facilitator Superfamily
LX00_06825	COG1960	acyl-CoA dehydrogenase activity
LX00_06840	COG1024	Enoyl-CoA hydratase
LX00_06855	COG2192	nodulation
LX00_06860	COG1280	lysine exporter protein (LysE YggA)
LX00_06875	COG0183	Belongs to the thiolase family
LX00_06880	COG1250	3-hydroxyacyl-CoA dehydrogenase
LX00_06885	COG1028	Short-chain dehydrogenase reductase Sdr
LX00_06890	COG1024	Enoyl-CoA hydratase
LX00_06895	COG1960	acyl-CoA dehydrogenase activity
LX00_06900	COG2814	Major facilitator Superfamily
LX00_06905	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LX00_06910	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LX00_06920	COG2814	Major facilitator Superfamily
LX00_06930	COG1960	acyl-CoA dehydrogenase activity
LX00_06945	COG0583	DNA-binding transcription factor activity
LX00_06960	COG1024	Enoyl-CoA hydratase
LX00_06965	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LX00_06970	COG1960	acyl-CoA dehydrogenase activity
LX00_06975	COG1309	transcriptional regulator
LX00_06980	COG0318	PFAM AMP-dependent synthetase and ligase
LX00_07000	COG0583	DNA-binding transcription factor activity
LX00_07050	COG1028	Short-chain dehydrogenase reductase Sdr
LX00_07070	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LX00_07090	COG2205	protein histidine kinase activity
LX00_07090	COG0784	Response regulator, receiver
LX00_07105	COG0765	amino acid transport
LX00_07110	COG0765	amino acid transport
LX00_07115	COG1126	abc transporter atp-binding protein
LX00_07120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LX00_07125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LX00_07135	COG1280	lysine exporter protein (LysE YggA)
LX00_07140	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LX00_07145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LX00_07150	COG1045	serine acetyltransferase
LX00_07165	COG0583	DNA-binding transcription factor activity
LX00_07170	COG0625	glutathione transferase activity
LX00_07175	COG0625	glutathione transferase activity
LX00_07180	COG0583	DNA-binding transcription factor activity
LX00_07190	COG1346	cytolysis
LX00_07210	COG2814	Major facilitator Superfamily
LX00_07220	COG0583	DNA-binding transcription factor activity
LX00_07230	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LX00_07235	COG3052	prosthetic group binding
LX00_07255	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LX00_07275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LX00_07285	COG1294	oxidase, subunit
LX00_07290	COG1271	oxidase subunit
LX00_07310	COG0477	Major facilitator Superfamily
LX00_07330	COG4521	taurine ABC transporter
LX00_07340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LX00_07345	COG2175	clavaminate synthase activity
LX00_07355	COG1953	Uracil, thiamine, allantoin
LX00_07365	COG0583	DNA-binding transcription factor activity
LX00_07375	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LX00_07390	COG0640	Transcriptional regulator
LX00_07395	COG0798	PFAM Bile acid sodium symporter
LX00_07400	COG0583	DNA-binding transcription factor activity
LX00_07415	COG3634	alkyl hydroperoxide reductase activity
LX00_07450	COG1301	dicarboxylic acid transport
LX00_07455	COG0436	Aminotransferase
LX00_07465	COG0386	Belongs to the glutathione peroxidase family
LX00_07480	COG0436	Aminotransferase
LX00_07505	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LX00_07530	COG0012	GTP binding
LX00_07535	COG2011	ABC-type metal ion transport system permease component
LX00_07540	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LX00_07550	COG1464	Belongs to the NlpA lipoprotein family
LX00_07580	COG0765	amino acid transport
LX00_07585	COG0765	amino acid transport
LX00_07590	COG1126	abc transporter atp-binding protein
LX00_07600	COG1522	sequence-specific DNA binding
LX00_07615	COG1309	transcriptional regulator
LX00_07640	COG0583	DNA-binding transcription factor activity
LX00_07650	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LX00_07660	COG0697	spore germination
LX00_07685	COG3121	Chaperone
LX00_07690	COG3539	Fimbrial protein
LX00_07715	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LX00_07715	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LX00_07770	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LX00_07780	COG2353	YceI-like domain
LX00_07790	COG3698	Phosphodiester glycosidase
LX00_07805	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LX00_07810	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LX00_07810	COG0506	proline dehydrogenase activity
LX00_07810	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LX00_07825	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LX00_07830	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LX00_07850	COG1132	(ABC) transporter
LX00_07855	COG3122	Protein conserved in bacteria
LX00_07860	COG3619	membrane
LX00_07870	COG0640	Transcriptional regulator
LX00_07880	COG2850	peptidyl-arginine hydroxylation
LX00_07885	COG0424	maF-like protein
LX00_07905	COG0191	fructose-bisphosphate aldolase activity
LX00_07910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LX00_07925	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LX00_07935	COG1192	Involved in chromosome partitioning
LX00_07940	COG1475	DNA binding
LX00_07945	COG0811	peptide transport
LX00_07955	COG1132	(ABC) transporter
LX00_07960	COG1663	tetraacyldisaccharide 4'-kinase activity
LX00_07980	COG0084	hydrolase, TatD family'
LX00_07995	COG2165	general secretion pathway protein
LX00_08025	COG0590	tRNA wobble adenosine to inosine editing
LX00_08045	COG0776	regulation of translation
LX00_08075	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LX00_08080	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LX00_08130	COG0339	signal peptide processing
LX00_08140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LX00_08175	COG0702	epimerase
LX00_08180	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LX00_08200	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LX00_08230	COG0316	Belongs to the HesB IscA family
LX00_08235	COG0822	iron-sulfur transferase activity
LX00_08260	COG0776	regulation of translation
LX00_08265	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LX00_08270	COG2207	Transcriptional regulator
LX00_08275	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LX00_08280	COG1960	acyl-CoA dehydrogenase activity
LX00_08285	COG1960	acyl-CoA dehydrogenase activity
LX00_08300	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LX00_08315	COG2814	Major facilitator Superfamily
LX00_08320	COG4264	IucA IucC family
LX00_08325	COG4264	IucA IucC family
LX00_08335	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LX00_08365	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LX00_08390	COG0406	alpha-ribazole phosphatase activity
LX00_08405	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LX00_08410	COG0730	response to heat
LX00_08435	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LX00_08450	COG1131	(ABC) transporter
LX00_08455	COG0842	Transport permease protein
LX00_08460	COG0842	Transport permease protein
LX00_08515	COG2226	methyltransferase
LX00_08540	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LX00_08585	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LX00_08595	COG0133	tryptophan synthase activity
LX00_08610	COG3706	GGDEF domain
LX00_08625	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LX00_08630	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LX00_08635	COG0022	dehydrogenase e1 component
LX00_08640	COG0508	dehydrogenase complex catalyzes the overall conversion of
LX00_08645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LX00_08655	COG1063	alcohol dehydrogenase
LX00_08660	COG3781	membrane
LX00_08670	COG3453	Protein conserved in bacteria
LX00_08670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LX00_08680	COG0730	response to heat
LX00_08695	COG3708	Transcriptional regulator
LX00_08695	COG2207	Transcriptional regulator
LX00_08700	COG1733	regulation of RNA biosynthetic process
LX00_08705	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LX00_08730	COG4521	taurine ABC transporter
LX00_08735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LX00_08755	COG0477	Major facilitator Superfamily
LX00_08765	COG1027	Aspartate ammonia-lyase
LX00_08780	COG0583	DNA-binding transcription factor activity
LX00_08785	COG0583	DNA-binding transcription factor activity
LX00_08790	COG0183	Belongs to the thiolase family
LX00_08795	COG2031	fatty acid transporter
LX00_08810	COG0583	DNA-binding transcription factor activity
LX00_08830	COG1309	transcriptional regulator
LX00_08840	COG2610	gluconate transmembrane transporter activity
LX00_08845	COG1028	Short-chain dehydrogenase reductase Sdr
LX00_08850	COG2207	Transcriptional regulator
LX00_08860	COG0412	Dienelactone hydrolase
LX00_08865	COG1028	Short-chain dehydrogenase reductase Sdr
LX00_08875	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LX00_08890	COG0543	2 iron, 2 sulfur cluster binding
LX00_08890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LX00_08895	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
LX00_08900	COG4638	Rieske (2fe-2S)
LX00_08910	COG0725	ABC transporter, periplasmic molybdate-binding protein
LX00_08915	COG4149	molybdate abc transporter
LX00_08920	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LX00_08925	COG1028	Short-chain dehydrogenase reductase Sdr
LX00_08930	COG1535	isochorismatase
LX00_08930	COG3433	isochorismatase activity
LX00_08945	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LX00_08955	COG0732	type I restriction modification DNA specificity domain
LX00_09015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LX00_09030	COG0753	catalase activity
LX00_09040	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LX00_09065	COG3539	Fimbrial protein
LX00_09220	COG0656	L-ascorbic acid biosynthetic process
LX00_09225	COG0494	nUDIX hydrolase
LX00_09245	COG1609	Transcriptional regulator
LX00_09255	COG0028	Belongs to the TPP enzyme family
LX00_09280	COG0483	inositol monophosphate 1-phosphatase activity
LX00_09295	COG0028	Belongs to the TPP enzyme family
LX00_09310	COG1346	cytolysis
LX00_09315	COG1609	Transcriptional regulator
LX00_09320	COG0412	Dienelactone hydrolase
LX00_09325	COG0697	spore germination
LX00_09335	COG2223	nitrite transmembrane transporter activity
LX00_09360	COG1028	Short-chain dehydrogenase reductase Sdr
LX00_09370	COG2267	carboxylic ester hydrolase activity
LX00_09385	COG3938	Belongs to the proline racemase family
LX00_09405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LX00_09425	COG2072	flavoprotein involved in K transport
LX00_09440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LX00_09445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LX00_09450	COG0745	RESPONSE REGULATOR receiver
LX00_09455	COG2205	protein histidine kinase activity
LX00_09465	COG2207	Transcriptional regulator
LX00_09475	COG1028	Short-chain dehydrogenase reductase Sdr
LX00_09485	COG1073	alpha beta
LX00_09550	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LX00_09605	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LX00_09625	COG1120	ATPase activity
LX00_09640	COG1064	alcohol dehydrogenase
LX00_09650	COG2207	Transcriptional regulator
LX00_09655	COG2084	Dehydrogenase
LX00_09665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LX00_09670	COG0583	DNA-binding transcription factor activity
LX00_09680	COG0129	dihydroxy-acid dehydratase activity
LX00_09685	COG1012	belongs to the aldehyde dehydrogenase family
LX00_09690	COG1846	Transcriptional regulator
LX00_09695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LX00_09700	COG1960	acyl-CoA dehydrogenase activity
LX00_09710	COG0477	Major facilitator Superfamily
LX00_09725	COG3971	2-oxopent-4-enoate hydratase activity
LX00_09735	COG3384	dioxygenase
LX00_09740	COG1012	belongs to the aldehyde dehydrogenase family
LX00_09750	COG0179	Fumarylacetoacetate (FAA) hydrolase
LX00_09760	COG2814	Major facilitator Superfamily
LX00_09765	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LX00_09800	COG0753	catalase activity
LX00_09815	COG1012	belongs to the aldehyde dehydrogenase family
LX00_09830	COG3162	membrane
LX00_09840	COG3829	transcription factor binding
LX00_09845	COG1028	Short-chain dehydrogenase reductase Sdr
LX00_09850	COG1960	acyl-CoA dehydrogenase activity
LX00_09865	COG3231	kanamycin kinase activity
LX00_09870	COG1012	belongs to the aldehyde dehydrogenase family
LX00_09890	COG2186	Transcriptional regulator
LX00_09900	COG0583	DNA-binding transcription factor activity
LX00_09905	COG4948	Mandelate Racemase Muconate Lactonizing
LX00_09910	COG4829	muconolactone delta-isomerase
LX00_09920	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LX00_09925	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LX00_09930	COG0183	Belongs to the thiolase family
LX00_09935	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LX00_09940	COG1012	belongs to the aldehyde dehydrogenase family
LX00_09950	COG3733	amine oxidase
LX00_09960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LX00_09970	COG1028	Short-chain dehydrogenase reductase Sdr
LX00_09980	COG4638	Rieske (2fe-2S)
LX00_10000	COG0154	amidase activity
LX00_10015	COG2814	Major facilitator Superfamily
LX00_10040	COG1960	acyl-CoA dehydrogenase activity
LX00_10045	COG0583	DNA-binding transcription factor activity
LX00_10050	COG1414	Transcriptional regulator
LX00_10065	COG2391	methyltransferase activity
LX00_10075	COG4993	Dehydrogenase
LX00_10080	COG3659	wide pore channel activity
LX00_10085	COG3420	alginic acid biosynthetic process
LX00_10090	COG0710	3-dehydroquinate dehydratase activity
LX00_10095	COG3485	protocatechuate 3,4-dioxygenase
LX00_10100	COG3485	protocatechuate 3,4-dioxygenase
LX00_10105	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LX00_10110	COG2271	Major facilitator Superfamily
LX00_10115	COG0596	Alpha beta hydrolase
LX00_10120	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LX00_10125	COG0183	Belongs to the thiolase family
LX00_10130	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LX00_10135	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LX00_10145	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LX00_10150	COG2323	membrane
LX00_10195	COG1902	pentaerythritol trinitrate reductase activity
LX00_10195	COG0446	pyridine nucleotide-disulphide oxidoreductase
LX00_10210	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LX00_10220	COG0542	response to heat
LX00_10225	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LX00_10255	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LX00_10260	COG0569	domain protein
LX00_10265	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LX00_10280	COG4774	siderophore transport
LX00_10285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LX00_10295	COG1585	Membrane protein implicated in regulation of membrane protease activity
LX00_10320	COG1294	oxidase, subunit
LX00_10325	COG4890	Cyd operon protein YbgT
LX00_10340	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
LX00_10350	COG0552	protein localization to endoplasmic reticulum
LX00_10375	COG0517	IMP dehydrogenase activity
LX00_10375	COG0516	GMP reductase activity
LX00_10380	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LX00_10385	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LX00_10395	COG0583	DNA-binding transcription factor activity
LX00_10400	COG0024	Methionine aminopeptidase
LX00_10430	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LX00_10430	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LX00_10435	COG1105	Belongs to the carbohydrate kinase PfkB family
LX00_10440	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LX00_10440	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LX00_10440	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LX00_10505	COG0776	regulation of translation
LX00_10560	COG4373	Mu-like prophage FluMu protein gp28
LX00_10580	COG4383	Mu-like prophage protein gp29
LX00_10585	COG2369	cell adhesion
LX00_10685	COG3299	homolog of phage Mu protein gp47
LX00_10740	COG2135	peptidase activity
LX00_10745	COG0659	secondary active sulfate transmembrane transporter activity
LX00_10760	COG1113	amino acid transport
LX00_10770	COG1522	sequence-specific DNA binding
LX00_10795	COG1011	Hydrolase
LX00_10800	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LX00_10810	COG2137	regulation of response to DNA damage stimulus
LX00_10820	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LX00_10855	COG0575	Belongs to the CDS family
LX00_10860	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LX00_10880	COG3852	Histidine kinase
LX00_10885	COG2204	response regulator
LX00_10940	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LX00_10945	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LX00_10965	COG0697	spore germination
LX00_10970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LX00_10980	COG0303	'Molybdopterin
LX00_10985	COG0315	cyclic pyranopterin monophosphate synthase activity
LX00_10985	COG0521	Mo-molybdopterin cofactor biosynthetic process
LX00_11000	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LX00_11005	COG0243	molybdopterin cofactor binding
LX00_11015	COG0243	molybdopterin cofactor binding
LX00_11020	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LX00_11025	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LX00_11025	COG2146	nitrite reductase [NAD(P)H] activity
LX00_11035	COG0745	RESPONSE REGULATOR receiver
LX00_11040	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LX00_11040	COG1116	anion transmembrane transporter activity
LX00_11055	COG0511	ligase activity, forming carbon-carbon bonds
LX00_11070	COG2814	Major facilitator Superfamily
LX00_11090	COG0069	glutamate synthase activity
LX00_11110	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LX00_11120	COG1454	alcohol dehydrogenase
LX00_11125	COG0824	Thioesterase
LX00_11155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LX00_11170	COG0183	Belongs to the thiolase family
LX00_11180	COG0583	DNA-binding transcription factor activity
LX00_11195	COG1522	sequence-specific DNA binding
LX00_11200	COG3135	benzoate transporter
LX00_11210	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LX00_11230	COG0589	response to stress
LX00_11240	COG2826	transposase and inactivated derivatives, IS30 family
LX00_11265	COG4773	Receptor
LX00_11295	COG0668	transmembrane transport
LX00_11305	COG1309	transcriptional regulator
LX00_11320	COG1605	Chorismate mutase
LX00_11340	COG0308	aminopeptidase N
LX00_11365	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LX00_11370	COG1454	alcohol dehydrogenase
LX00_11390	COG0531	amino acid
LX00_11395	COG4303	Ethanolamine ammonia lyase large subunit
LX00_11400	COG4302	ethanolamine ammonia-lyase activity
LX00_11405	COG0519	Catalyzes the synthesis of GMP from XMP
LX00_11405	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LX00_11435	COG0697	spore germination
LX00_11440	COG1923	regulation of RNA biosynthetic process
LX00_11450	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LX00_11455	COG0802	atpase or kinase
LX00_11475	COG1187	pseudouridine synthase activity
LX00_11490	COG0583	DNA-binding transcription factor activity
LX00_11505	COG2814	Major facilitator Superfamily
LX00_11510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LX00_11535	COG0729	surface antigen
LX00_11555	COG0174	glutamine synthetase
LX00_11560	COG0745	RESPONSE REGULATOR receiver
LX00_11565	COG2205	protein histidine kinase activity
LX00_11575	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LX00_11580	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LX00_11605	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LX00_11610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LX00_11615	COG1960	acyl-CoA dehydrogenase activity
LX00_11645	COG0583	DNA-binding transcription factor activity
LX00_11660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LX00_11670	COG3658	cytochrome
LX00_11675	COG1215	transferase activity, transferring glycosyl groups
LX00_11680	COG1649	PFAM Uncharacterised BCR, COG1649
LX00_11680	COG0726	polysaccharide deacetylase
LX00_11705	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LX00_11710	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LX00_11720	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LX00_11745	COG0305	Participates in initiation and elongation during chromosome replication
LX00_11750	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LX00_11760	COG1305	Transglutaminase-like
LX00_11770	COG2308	Evidence 4 Homologs of previously reported genes of
LX00_11805	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LX00_11810	COG0138	bifunctional purine biosynthesis protein purh
LX00_11815	COG0151	Belongs to the GarS family
LX00_11820	COG1464	Belongs to the NlpA lipoprotein family
LX00_11825	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LX00_11830	COG2011	ABC-type metal ion transport system permease component
LX00_11835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LX00_11845	COG1301	dicarboxylic acid transport
LX00_11875	COG1794	racemase activity, acting on amino acids and derivatives
LX00_11885	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LX00_11885	COG3008	intermembrane lipid transfer
LX00_11890	COG2995	paraquat-inducible protein a
LX00_11900	COG2985	domain, Protein
LX00_11925	COG0477	Major facilitator Superfamily
LX00_11975	COG2186	Transcriptional regulator
LX00_11985	COG0786	glutamate:sodium symporter activity
LX00_11990	COG3243	poly(R)-hydroxyalkanoic acid synthase
LX00_12015	COG3111	PFAM Bacterial OB fold (BOF) protein
LX00_12100	COG3210	domain, Protein
LX00_12100	COG3210	domain, Protein
LX00_12105	COG2831	hemolysin activation secretion protein
LX00_12165	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LX00_12170	COG1610	YqeY-like protein
LX00_12175	COG4783	chaperone-mediated protein folding
LX00_12200	COG1286	toxin biosynthetic process
LX00_12230	COG0778	Nitroreductase
LX00_12240	COG0513	Belongs to the DEAD box helicase family
LX00_12260	COG2363	Small membrane protein
LX00_12290	COG1234	tRNA 3'-trailer cleavage
LX00_12295	COG2195	Cleaves the N-terminal amino acid of tripeptides
LX00_12305	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LX00_12315	COG2819	hydrolase of the alpha beta superfamily
LX00_12320	COG1960	acyl-CoA dehydrogenase activity
LX00_12325	COG1301	dicarboxylic acid transport
LX00_12330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LX00_12335	COG3139	Protein of unknown function (DUF1315)
LX00_12340	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LX00_12345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LX00_12355	COG0494	nUDIX hydrolase
LX00_12365	COG0642	Histidine kinase
LX00_12370	COG0745	RESPONSE REGULATOR receiver
LX00_12390	COG1720	tRNA m6t6A37 methyltransferase activity
LX00_12405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LX00_12415	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LX00_12425	COG4598	ABC transporter
LX00_12430	COG4160	amino acid transport
LX00_12435	COG4215	(ABC) transporter
LX00_12455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LX00_12465	COG1538	Outer membrane efflux protein
LX00_12495	COG1131	(ABC) transporter
LX00_12500	COG0842	Transport permease protein
LX00_12515	COG0772	Belongs to the SEDS family
LX00_12520	COG2951	lytic endotransglycosylase activity
LX00_12545	COG2207	Transcriptional regulator
LX00_12560	COG0052	Belongs to the universal ribosomal protein uS2 family
LX00_12565	COG0024	Methionine aminopeptidase
LX00_12575	COG2223	nitrite transmembrane transporter activity
LX00_12590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LX00_12595	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LX00_12600	COG1960	acyl-CoA dehydrogenase activity
LX00_12615	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LX00_12620	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LX00_12625	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LX00_12645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LX00_12650	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LX00_12655	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LX00_12685	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LX00_12700	COG3104	oligopeptide transport
LX00_12710	COG0582	viral genome integration into host DNA
LX00_12820	COG3566	protein conserved in bacteria
LX00_12840	COG3567	Phage-associated protein, HI1409 family
LX00_12845	COG5410	chromosome segregation
LX00_12990	COG0512	Glutamine amidotransferase of anthranilate synthase
LX00_13025	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LX00_13065	COG3739	integral membrane protein
LX00_13080	COG1169	isochorismate synthase
LX00_13090	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LX00_13095	COG5265	(ABC) transporter
LX00_13100	COG1132	(ABC) transporter
LX00_13115	COG1535	isochorismatase
LX00_13115	COG3433	isochorismatase activity
LX00_13120	COG1021	2,3-dihydroxybenzoate-AMP ligase
LX00_13125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LX00_13135	COG4774	siderophore transport
LX00_13140	COG4607	ABC-type enterochelin transport system periplasmic component
LX00_13145	COG4604	ABC transporter, ATP-binding protein
LX00_13150	COG4605	iron ion homeostasis
LX00_13155	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LX00_13160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LX00_13175	COG2964	Protein conserved in bacteria
LX00_13185	COG1741	Belongs to the pirin family
LX00_13225	COG2879	small protein
LX00_13230	COG1966	Carbon starvation protein
LX00_13250	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LX00_13270	COG2211	Major facilitator Superfamily
LX00_13275	COG1067	ATP-dependent peptidase activity
LX00_13280	COG0583	DNA-binding transcription factor activity
LX00_13305	COG1686	Belongs to the peptidase S11 family
LX00_13310	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LX00_13345	COG0616	signal peptide processing
LX00_13350	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LX00_13360	COG0573	inorganic phosphate transmembrane transporter activity
LX00_13365	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LX00_13370	COG1113	amino acid transport
LX00_13375	COG3961	Belongs to the TPP enzyme family
LX00_13380	COG1522	sequence-specific DNA binding
LX00_13390	COG0076	glutamate decarboxylase activity
LX00_13395	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LX00_13405	COG1309	transcriptional regulator
LX00_13420	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LX00_13455	COG0352	thiamine-phosphate diphosphorylase activity
LX00_13480	COG0612	Peptidase, M16
LX00_13495	COG0583	DNA-binding transcription factor activity
LX00_13500	COG0477	Major facilitator Superfamily
LX00_13520	COG1187	pseudouridine synthase activity
LX00_13535	COG1686	Belongs to the peptidase S11 family
LX00_13540	COG1252	NADH dehydrogenase
LX00_13550	COG0415	Belongs to the DNA photolyase family
LX00_13565	COG1215	transferase activity, transferring glycosyl groups
LX00_13595	COG2070	2-Nitropropane dioxygenase
LX00_13650	COG0556	nucleotide-excision repair
LX00_13695	COG4221	oxidoreductase activity
LX00_13705	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LX00_13710	COG1381	Involved in DNA repair and RecF pathway recombination
LX00_13720	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LX00_13735	COG0681	Belongs to the peptidase S26 family
LX00_13750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LX00_13770	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LX00_13775	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LX00_13780	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LX00_13790	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LX00_13795	COG4208	sulfate ABC transporter
LX00_13800	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LX00_13805	COG0583	DNA-binding transcription factor activity
LX00_13810	COG4625	pathogenesis
LX00_13825	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LX00_13840	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LX00_13850	COG1056	cytidyltransferase-related domain
LX00_13850	COG1051	belongs to the nudix hydrolase family
LX00_13855	COG1024	Enoyl-CoA hydratase
LX00_13870	COG2814	Major facilitator Superfamily
LX00_13875	COG0047	phosphoribosylformylglycinamidine synthase activity
LX00_13875	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LX00_13895	COG1473	amidohydrolase
LX00_13900	COG0824	Thioesterase
LX00_13920	COG0823	Involved in the tonB-independent uptake of proteins
LX00_13940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LX00_13975	COG0628	permease
LX00_13985	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LX00_13990	COG0596	Alpha beta hydrolase
LX00_13995	COG0616	signal peptide processing
LX00_13995	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LX00_14005	COG0658	competence protein
LX00_14005	COG2333	competence protein COMEC
LX00_14010	COG1136	(ABC) transporter
LX00_14015	COG4591	ABC-type transport system involved in lipoprotein release permease component
LX00_14050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LX00_14070	COG0463	Glycosyl transferase, family 2
LX00_14100	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LX00_14105	COG1280	lysine exporter protein (LysE YggA)
LX00_14115	COG0019	diaminopimelate decarboxylase activity
LX00_14125	COG1113	amino acid transport
LX00_14140	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LX00_14150	COG3339	Conserved Protein
LX00_14155	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LX00_14160	COG0243	molybdopterin cofactor binding
LX00_14165	COG1929	Belongs to the glycerate kinase type-1 family
LX00_14180	COG0778	Nitroreductase
LX00_14230	COG3811	Belongs to the UPF0386 family
LX00_14240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LX00_14255	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LX00_14275	COG0741	lytic transglycosylase activity
LX00_14295	COG0584	glycerophosphoryl diester phosphodiesterase
LX00_14325	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LX00_14345	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LX00_14350	COG0477	Major facilitator Superfamily
LX00_14405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LX00_14410	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LX00_14435	COG0505	Belongs to the CarA family
LX00_14455	COG0589	response to stress
LX00_14470	COG2843	Capsule synthesis protein
LX00_14490	COG2321	neutral zinc metallopeptidase
LX00_14495	COG2354	Protein conserved in bacteria
LX00_14515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LX00_14530	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LX00_14535	COG1053	succinate dehydrogenase
LX00_14540	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LX00_14545	COG2009	succinate dehydrogenase
LX00_14585	COG2921	Belongs to the UPF0250 family
LX00_14590	COG0321	lipoyl(octanoyl) transferase activity
LX00_14605	COG0531	amino acid
LX00_14615	COG1733	regulation of RNA biosynthetic process
LX00_14620	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LX00_14625	COG1648	precorrin-2 dehydrogenase activity
LX00_14625	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LX00_14640	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LX00_14665	COG0215	cysteine-tRNA ligase activity
LX00_14670	COG0671	phosphoesterase, PA-phosphatase related
LX00_14675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LX00_14685	COG1538	Outer membrane efflux protein
LX00_14690	COG0393	Putative heavy-metal-binding
LX00_14695	COG0393	Putative heavy-metal-binding
LX00_14705	COG1028	Short-chain dehydrogenase reductase Sdr
LX00_14715	COG0525	valine-tRNA ligase activity
LX00_14735	COG0583	DNA-binding transcription factor activity
LX00_14740	COG0004	ammonium transporteR
LX00_14750	COG0642	Histidine kinase
LX00_14755	COG0745	RESPONSE REGULATOR receiver
LX00_14760	COG2194	sulfuric ester hydrolase activity
LX00_14785	COG1752	Esterase of the alpha-beta hydrolase superfamily
LX00_14955	COG3728	DNA packaging
LX00_15065	COG0305	Participates in initiation and elongation during chromosome replication
LX00_15095	COG3620	sequence-specific DNA binding
LX00_15130	COG2207	Transcriptional regulator
LX00_15160	COG2249	NAD(P)H dehydrogenase (quinone) activity
LX00_15180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LX00_15190	COG1530	ribonuclease E activity
LX00_15195	COG0424	maF-like protein
LX00_15200	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LX00_15205	COG1792	Involved in formation and maintenance of cell shape
LX00_15210	COG1077	Cell shape determining protein MreB Mrl
LX00_15215	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LX00_15225	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LX00_15250	COG3590	peptidase
LX00_15255	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
LX00_15260	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LX00_15265	COG1752	Esterase of the alpha-beta hydrolase superfamily
LX00_15270	COG1115	amino acid carrier protein
LX00_15290	COG2814	Major facilitator Superfamily
LX00_15295	COG1289	transmembrane transporter activity
LX00_15345	COG1376	ErfK ybiS ycfS ynhG family protein
LX00_15350	COG2832	Protein of unknown function (DUF454)
LX00_15360	COG5510	response to toxic substance
LX00_15380	COG0840	transmembrane signaling receptor activity
LX00_15420	COG3422	double-strand break repair
LX00_15425	COG2824	Alkylphosphonate utilization operon protein PhnA
LX00_15430	COG3189	MarR family transcriptional regulator
LX00_15440	COG0354	folic acid binding
LX00_15445	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LX00_15455	COG0679	Auxin Efflux Carrier
LX00_15460	COG1902	pentaerythritol trinitrate reductase activity
LX00_15465	COG4772	TonB-dependent receptor
LX00_15470	COG2094	Belongs to the DNA glycosylase MPG family
LX00_15500	COG2233	PERMEase
LX00_15510	COG0833	amino acid
LX00_15515	COG1690	Belongs to the RtcB family
LX00_15525	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LX00_15525	COG2885	chlorophyll binding
LX00_15535	COG0183	Belongs to the thiolase family
LX00_15555	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LX00_15575	COG2207	Transcriptional regulator
LX00_15580	COG0183	Belongs to the thiolase family
LX00_15610	COG1272	protein, Hemolysin III
LX00_15615	COG0477	Major facilitator Superfamily
LX00_15630	COG0450	alkyl hydroperoxide reductase
LX00_15650	COG0285	dihydrofolate synthase activity
LX00_15685	COG0133	tryptophan synthase activity
LX00_15695	COG4206	TonB-dependent receptor
LX00_15700	COG2096	Adenosyltransferase
LX00_15720	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LX00_15725	COG0745	RESPONSE REGULATOR receiver
LX00_15730	COG2205	protein histidine kinase activity
LX00_15740	COG1960	acyl-CoA dehydrogenase activity
LX00_15745	COG1960	acyl-CoA dehydrogenase activity
LX00_15820	COG0438	transferase activity, transferring glycosyl groups
LX00_15825	COG0463	Glycosyl transferase, family 2
LX00_15830	COG0726	polysaccharide deacetylase
LX00_15850	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LX00_15905	COG1862	Preprotein translocase
LX00_15915	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LX00_15920	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LX00_15930	COG3781	membrane
LX00_15935	COG0613	PHP domain protein
LX00_15945	COG2350	Protein conserved in bacteria
LX00_15975	COG1607	acyl-coa hydrolase
LX00_15990	COG3453	Protein conserved in bacteria
LX00_15990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LX00_16030	COG2826	transposase and inactivated derivatives, IS30 family
LX00_16040	COG2199	diguanylate cyclase activity
LX00_16050	COG1408	metallophosphoesterase
LX00_16055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LX00_16065	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LX00_16085	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LX00_16090	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LX00_16105	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LX00_16115	COG2969	positive regulation of protein catabolic process
LX00_16135	COG1960	acyl-CoA dehydrogenase activity
LX00_16140	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LX00_16155	COG1309	transcriptional regulator
LX00_16160	COG1960	acyl-CoA dehydrogenase activity
LX00_16205	COG1183	phosphatidylcholine synthase activity
LX00_16210	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LX00_16240	COG0739	heme binding
LX00_16240	COG0741	lytic transglycosylase activity
LX00_16240	COG1196	nuclear chromosome segregation
LX00_16250	COG1702	phosphate starvation-inducible protein PhoH
LX00_16285	COG1295	ribonuclease BN
LX00_16290	COG0697	spore germination
LX00_16300	COG0179	Fumarylacetoacetate (FAA) hydrolase
LX00_16330	COG2826	transposase and inactivated derivatives, IS30 family
LX00_16355	COG0557	exoribonuclease II activity
LX00_16360	COG0339	signal peptide processing
LX00_16365	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LX00_16400	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LX00_16405	COG1960	acyl-CoA dehydrogenase activity
LX00_16430	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LX00_16440	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LX00_16560	COG0626	cystathionine gamma-synthase activity
LX00_16565	COG0433	COG0433 Predicted ATPase
LX00_16570	COG1017	nitric oxide dioxygenase activity
LX00_16570	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LX00_16575	COG1959	2 iron, 2 sulfur cluster binding
LX00_16590	COG1301	dicarboxylic acid transport
LX00_16595	COG1946	Acyl-CoA thioesterase
LX00_16620	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LX00_16625	COG1040	competence protein
LX00_16630	COG0494	nUDIX hydrolase
LX00_16640	COG0598	Magnesium transport protein CorA
LX00_16650	COG2854	intermembrane phospholipid transfer
LX00_16660	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LX00_16665	COG1127	ABC transporter
LX00_16675	COG0513	Belongs to the DEAD box helicase family
LX00_16695	COG0408	coproporphyrinogen oxidase activity
LX00_16710	COG1960	acyl-CoA dehydrogenase activity
LX00_16720	COG1983	PspC domain protein
LX00_16725	COG0517	IMP dehydrogenase activity
LX00_16760	COG1106	Psort location Cytoplasmic, score
LX00_16780	COG0583	DNA-binding transcription factor activity
LX00_16820	COG1012	belongs to the aldehyde dehydrogenase family
LX00_16830	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LX00_16835	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LX00_16845	COG0833	amino acid
LX00_16875	COG1192	Involved in chromosome partitioning
LX00_16880	COG0628	permease
LX00_16890	COG1289	transmembrane transporter activity
LX00_16905	COG2249	NAD(P)H dehydrogenase (quinone) activity
LX00_16910	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LX00_16925	COG0277	FAD linked oxidase domain protein
LX00_16930	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LX00_16955	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LX00_16960	COG5380	lipid catabolic process
LX00_16980	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LX00_17030	COG0194	GDP metabolic process
LX00_17040	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LX00_17060	COG3307	-O-antigen
LX00_17080	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LX00_17085	COG1704	LemA family
LX00_17095	COG0493	'glutamate synthase
LX00_17100	COG0067	glutamate synthase
LX00_17100	COG0070	glutamate synthase
LX00_17100	COG0069	glutamate synthase activity
LX00_17150	COG2226	methyltransferase
LX00_17165	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LX00_17170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LX00_17290	COG0488	(ABC) transporter
LX00_17300	COG4221	oxidoreductase activity
LX00_17305	COG0659	secondary active sulfate transmembrane transporter activity
LX00_17315	COG0745	RESPONSE REGULATOR receiver
LX00_17325	COG0427	acetyl-CoA hydrolase
LX00_17355	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LX00_17385	COG2329	Antibiotic biosynthesis monooxygenase
LX00_17400	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LX00_17475	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LX00_17485	COG3316	Transposase and inactivated derivatives
LX00_17515	COG1660	Displays ATPase and GTPase activities
LX00_17535	COG3316	Transposase and inactivated derivatives
LX00_17605	COG2249	NAD(P)H dehydrogenase (quinone) activity
LX00_17610	COG1733	regulation of RNA biosynthetic process
LX00_17645	COG0667	Aldo Keto reductase
LX00_17665	COG0583	DNA-binding transcription factor activity
LX00_17670	COG2814	Major facilitator Superfamily
LX00_17680	COG1113	amino acid transport
LX00_17700	COG2508	Transcriptional regulator
LX00_17700	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LX00_17735	COG1335	isochorismatase
LX00_17745	COG1012	belongs to the aldehyde dehydrogenase family
LX00_17750	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LX00_17760	COG1113	amino acid transport
LX00_17770	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LX00_17785	COG2814	Major facilitator Superfamily
LX00_17795	COG0352	thiamine-phosphate diphosphorylase activity
LX00_17795	COG0351	phosphomethylpyrimidine kinase
LX00_17795	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LX00_17815	COG1309	transcriptional regulator
LX00_17820	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LX00_17825	COG3706	GGDEF domain
LX00_17835	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LX00_17845	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LX00_17850	COG3162	membrane
LX00_17855	COG2205	protein histidine kinase activity
LX00_17855	COG2198	Histidine kinase
LX00_17855	COG0784	Response regulator, receiver
LX00_17880	COG1522	sequence-specific DNA binding
LX00_17885	COG1335	isochorismatase
LX00_17890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LX00_17900	COG0668	transmembrane transport
LX00_17905	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LX00_17910	COG1519	Transferase
LX00_17915	COG1902	pentaerythritol trinitrate reductase activity
LX00_17935	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LX00_17960	COG0426	domain, Protein
LX00_17960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LX00_17965	COG4774	siderophore transport
LX00_17970	COG2119	membrane
LX00_17980	COG0508	dehydrogenase complex catalyzes the overall conversion of
LX00_17990	COG4942	peptidase
LX00_18005	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LX00_18015	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LX00_18035	COG0189	ligase activity
LX00_18055	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LX00_18070	COG0708	Exodeoxyribonuclease III
LX00_18075	COG1393	Belongs to the ArsC family
LX00_18090	COG3706	GGDEF domain
LX00_18125	COG2351	hydroxyisourate hydrolase activity
LX00_18130	COG2233	PERMEase
LX00_18140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LX00_18150	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
LX00_18160	COG3150	esterase
LX00_18200	COG3501	Rhs element vgr protein
LX00_18210	COG2918	glutathione biosynthetic process
LX00_18225	COG2733	membrane
LX00_18230	COG0436	Aminotransferase
LX00_18235	COG0534	Mate efflux family protein
LX00_18320	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LX00_18325	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LX00_18335	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LX00_18340	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LX00_18355	COG0010	Belongs to the arginase family
LX00_18385	COG2188	Transcriptional regulator
LX00_18395	COG0523	cobalamin synthesis protein
LX00_18405	COG1113	amino acid transport
LX00_18415	COG0625	glutathione transferase activity
LX00_18435	COG1683	Conserved Protein
LX00_18440	COG0534	Mate efflux family protein
LX00_18445	COG0385	Bile acid
LX00_18450	COG1335	isochorismatase
LX00_18455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LX00_18475	COG2116	formate transmembrane transporter activity
LX00_18480	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LX00_18485	COG2133	pyrroloquinoline quinone binding
LX00_18490	COG2983	Belongs to the UPF0260 family
LX00_18510	COG1194	a g-specific adenine glycosylase
LX00_18525	COG2818	Glycosylase
LX00_18530	COG1064	alcohol dehydrogenase
LX00_18535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LX00_18545	COG0583	DNA-binding transcription factor activity
LX00_18550	COG0656	L-ascorbic acid biosynthetic process
LX00_18555	COG2814	Major facilitator Superfamily
LX00_18590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LX00_18605	COG2233	PERMEase
LX00_18610	COG0583	DNA-binding transcription factor activity
LX00_18645	COG0733	neurotransmitter:sodium symporter activity