locus-tag	class	description
CTI08_00010	COG0592	DNA-directed DNA polymerase activity
CTI08_00020	COG0187	DNA topoisomerase II activity
CTI08_00030	COG0586	Pfam SNARE associated Golgi protein
CTI08_00035	COG0488	(ABC) transporter
CTI08_00060	COG0596	Alpha beta hydrolase
CTI08_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CTI08_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CTI08_00115	COG0733	neurotransmitter:sodium symporter activity
CTI08_00155	COG2233	PERMEase
CTI08_00170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTI08_00205	COG2814	Major facilitator Superfamily
CTI08_00210	COG0656	L-ascorbic acid biosynthetic process
CTI08_00215	COG0583	DNA-binding transcription factor activity
CTI08_00230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTI08_00235	COG1064	alcohol dehydrogenase
CTI08_00240	COG2818	Glycosylase
CTI08_00255	COG1194	a g-specific adenine glycosylase
CTI08_00275	COG2983	Belongs to the UPF0260 family
CTI08_00280	COG2133	pyrroloquinoline quinone binding
CTI08_00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CTI08_00290	COG2116	formate transmembrane transporter activity
CTI08_00315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTI08_00320	COG1335	isochorismatase
CTI08_00325	COG0385	Bile acid
CTI08_00330	COG0534	Mate efflux family protein
CTI08_00335	COG1683	Conserved Protein
CTI08_00355	COG0625	glutathione transferase activity
CTI08_00365	COG1113	amino acid transport
CTI08_00375	COG0523	cobalamin synthesis protein
CTI08_00385	COG2188	Transcriptional regulator
CTI08_00415	COG0010	Belongs to the arginase family
CTI08_00425	COG0546	phosphoglycolate phosphatase activity
CTI08_00430	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CTI08_00445	COG0084	hydrolase, TatD family'
CTI08_00470	COG1169	isochorismate synthase
CTI08_00475	COG3433	isochorismatase activity
CTI08_00475	COG1535	isochorismatase
CTI08_00480	COG1028	Short-chain dehydrogenase reductase Sdr
CTI08_00485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTI08_00490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTI08_00490	COG2226	methyltransferase
CTI08_00490	COG3433	isochorismatase activity
CTI08_00495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTI08_00500	COG1021	2,3-dihydroxybenzoate-AMP ligase
CTI08_00505	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CTI08_00510	COG0019	diaminopimelate decarboxylase activity
CTI08_00530	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CTI08_00535	COG4774	siderophore transport
CTI08_00550	COG0534	Mate efflux family protein
CTI08_00560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTI08_00635	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CTI08_00645	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CTI08_00650	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CTI08_00700	COG0753	catalase activity
CTI08_00760	COG0534	Mate efflux family protein
CTI08_00765	COG0436	Aminotransferase
CTI08_00770	COG2733	membrane
CTI08_00785	COG2918	glutathione biosynthetic process
CTI08_00795	COG3501	Rhs element vgr protein
CTI08_00800	COG3179	chitinase
CTI08_00825	COG3150	esterase
CTI08_00835	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CTI08_00845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTI08_00855	COG2233	PERMEase
CTI08_00910	COG1393	Belongs to the ArsC family
CTI08_00915	COG0708	Exodeoxyribonuclease III
CTI08_00935	COG0189	ligase activity
CTI08_00955	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CTI08_00965	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CTI08_00980	COG4942	peptidase
CTI08_00990	COG0508	dehydrogenase complex catalyzes the overall conversion of
CTI08_01000	COG2119	membrane
CTI08_01005	COG4774	siderophore transport
CTI08_01010	COG0426	domain, Protein
CTI08_01010	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTI08_01035	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CTI08_01055	COG1902	pentaerythritol trinitrate reductase activity
CTI08_01060	COG1519	Transferase
CTI08_01065	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CTI08_01070	COG0668	transmembrane transport
CTI08_01080	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTI08_01085	COG1335	isochorismatase
CTI08_01090	COG1522	sequence-specific DNA binding
CTI08_01115	COG0784	Response regulator, receiver
CTI08_01115	COG2198	Histidine kinase
CTI08_01115	COG2205	protein histidine kinase activity
CTI08_01120	COG3162	membrane
CTI08_01125	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CTI08_01135	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTI08_01160	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CTI08_01165	COG1309	transcriptional regulator
CTI08_01185	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CTI08_01185	COG0352	thiamine-phosphate diphosphorylase activity
CTI08_01185	COG0351	phosphomethylpyrimidine kinase
CTI08_01195	COG2814	Major facilitator Superfamily
CTI08_01210	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CTI08_01220	COG1113	amino acid transport
CTI08_01230	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CTI08_01235	COG1012	belongs to the aldehyde dehydrogenase family
CTI08_01245	COG1335	isochorismatase
CTI08_01275	COG2814	Major facilitator Superfamily
CTI08_01280	COG0583	DNA-binding transcription factor activity
CTI08_01305	COG0667	Aldo Keto reductase
CTI08_01330	COG1733	regulation of RNA biosynthetic process
CTI08_01345	COG1733	regulation of RNA biosynthetic process
CTI08_01355	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTI08_01370	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CTI08_01375	COG2207	Transcriptional regulator
CTI08_01430	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CTI08_01470	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CTI08_01500	COG0427	acetyl-CoA hydrolase
CTI08_01515	COG0745	RESPONSE REGULATOR receiver
CTI08_01540	COG4221	oxidoreductase activity
CTI08_01550	COG0488	(ABC) transporter
CTI08_01615	COG0833	amino acid
CTI08_01660	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CTI08_01665	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CTI08_01680	COG2226	methyltransferase
CTI08_01730	COG0067	glutamate synthase
CTI08_01730	COG0069	glutamate synthase activity
CTI08_01730	COG0070	glutamate synthase
CTI08_01735	COG0493	'glutamate synthase
CTI08_01745	COG1704	LemA family
CTI08_01750	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CTI08_01770	COG3307	-O-antigen
CTI08_01790	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CTI08_01800	COG0194	GDP metabolic process
CTI08_01850	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CTI08_01870	COG5380	lipid catabolic process
CTI08_01875	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CTI08_01900	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CTI08_01905	COG0277	FAD linked oxidase domain protein
CTI08_01915	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CTI08_01920	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTI08_01935	COG1289	transmembrane transporter activity
CTI08_01945	COG0628	permease
CTI08_01950	COG1192	Involved in chromosome partitioning
CTI08_01980	COG0833	amino acid
CTI08_01985	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CTI08_01990	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CTI08_02000	COG1012	belongs to the aldehyde dehydrogenase family
CTI08_02040	COG0583	DNA-binding transcription factor activity
CTI08_02085	COG0517	IMP dehydrogenase activity
CTI08_02090	COG1983	PspC domain protein
CTI08_02100	COG1960	acyl-CoA dehydrogenase activity
CTI08_02115	COG0408	coproporphyrinogen oxidase activity
CTI08_02135	COG0513	Belongs to the DEAD box helicase family
CTI08_02140	COG1127	ABC transporter
CTI08_02145	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CTI08_02155	COG2854	intermembrane phospholipid transfer
CTI08_02165	COG0598	Magnesium transport protein CorA
CTI08_02175	COG0494	nUDIX hydrolase
CTI08_02180	COG1040	competence protein
CTI08_02185	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CTI08_02205	COG1946	Acyl-CoA thioesterase
CTI08_02210	COG1301	dicarboxylic acid transport
CTI08_02225	COG1959	2 iron, 2 sulfur cluster binding
CTI08_02230	COG1017	nitric oxide dioxygenase activity
CTI08_02230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTI08_02235	COG0433	COG0433 Predicted ATPase
CTI08_02240	COG0626	cystathionine gamma-synthase activity
CTI08_02360	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CTI08_02370	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CTI08_02395	COG1960	acyl-CoA dehydrogenase activity
CTI08_02400	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CTI08_02430	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CTI08_02435	COG0339	signal peptide processing
CTI08_02440	COG0557	exoribonuclease II activity
CTI08_02485	COG0179	Fumarylacetoacetate (FAA) hydrolase
CTI08_02490	COG2169	Transcriptional regulator
CTI08_02495	COG0697	spore germination
CTI08_02500	COG1295	ribonuclease BN
CTI08_02535	COG1702	phosphate starvation-inducible protein PhoH
CTI08_02545	COG1196	nuclear chromosome segregation
CTI08_02545	COG0741	lytic transglycosylase activity
CTI08_02545	COG0739	heme binding
CTI08_02575	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CTI08_02580	COG1183	phosphatidylcholine synthase activity
CTI08_02625	COG1960	acyl-CoA dehydrogenase activity
CTI08_02630	COG1309	transcriptional regulator
CTI08_02645	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CTI08_02650	COG1960	acyl-CoA dehydrogenase activity
CTI08_02670	COG2969	positive regulation of protein catabolic process
CTI08_02680	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CTI08_02695	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CTI08_02700	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CTI08_02720	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CTI08_02730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CTI08_02735	COG1408	metallophosphoesterase
CTI08_02745	COG2199	diguanylate cyclase activity
CTI08_02800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTI08_02800	COG3453	Protein conserved in bacteria
CTI08_02815	COG1607	acyl-coa hydrolase
CTI08_02845	COG2350	Protein conserved in bacteria
CTI08_02855	COG0613	PHP domain protein
CTI08_02860	COG3781	membrane
CTI08_02870	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CTI08_02875	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CTI08_02885	COG1862	Preprotein translocase
CTI08_02935	COG2205	protein histidine kinase activity
CTI08_02940	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CTI08_02960	COG0726	polysaccharide deacetylase
CTI08_02965	COG0463	Glycosyl transferase, family 2
CTI08_02970	COG0438	transferase activity, transferring glycosyl groups
CTI08_03035	COG0625	glutathione transferase activity
CTI08_03040	COG0583	DNA-binding transcription factor activity
CTI08_03045	COG1960	acyl-CoA dehydrogenase activity
CTI08_03050	COG1960	acyl-CoA dehydrogenase activity
CTI08_03060	COG2205	protein histidine kinase activity
CTI08_03065	COG0745	RESPONSE REGULATOR receiver
CTI08_03070	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CTI08_03090	COG2096	Adenosyltransferase
CTI08_03105	COG0133	tryptophan synthase activity
CTI08_03140	COG0285	dihydrofolate synthase activity
CTI08_03160	COG0450	alkyl hydroperoxide reductase
CTI08_03175	COG0477	Major facilitator Superfamily
CTI08_03180	COG1272	protein, Hemolysin III
CTI08_03210	COG0183	Belongs to the thiolase family
CTI08_03215	COG2207	Transcriptional regulator
CTI08_03235	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTI08_03255	COG0183	Belongs to the thiolase family
CTI08_03265	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CTI08_03265	COG2885	chlorophyll binding
CTI08_03275	COG1690	Belongs to the RtcB family
CTI08_03280	COG0833	amino acid
CTI08_03290	COG2233	PERMEase
CTI08_03320	COG2094	Belongs to the DNA glycosylase MPG family
CTI08_03325	COG4772	TonB-dependent receptor
CTI08_03330	COG1902	pentaerythritol trinitrate reductase activity
CTI08_03335	COG0679	Auxin Efflux Carrier
CTI08_03345	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CTI08_03350	COG0354	folic acid binding
CTI08_03360	COG3189	MarR family transcriptional regulator
CTI08_03365	COG2824	Alkylphosphonate utilization operon protein PhnA
CTI08_03370	COG3422	double-strand break repair
CTI08_03415	COG0840	transmembrane signaling receptor activity
CTI08_03435	COG5510	response to toxic substance
CTI08_03445	COG2832	Protein of unknown function (DUF454)
CTI08_03450	COG1376	ErfK ybiS ycfS ynhG family protein
CTI08_03500	COG1289	transmembrane transporter activity
CTI08_03505	COG2814	Major facilitator Superfamily
CTI08_03525	COG1115	amino acid carrier protein
CTI08_03530	COG1752	Esterase of the alpha-beta hydrolase superfamily
CTI08_03535	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CTI08_03540	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CTI08_03570	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CTI08_03580	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CTI08_03585	COG1077	Cell shape determining protein MreB Mrl
CTI08_03590	COG1792	Involved in formation and maintenance of cell shape
CTI08_03595	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CTI08_03600	COG0424	maF-like protein
CTI08_03605	COG1530	ribonuclease E activity
CTI08_03615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTI08_03635	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTI08_03660	COG2207	Transcriptional regulator
CTI08_03680	COG1113	amino acid transport
CTI08_03685	COG2828	Protein conserved in bacteria
CTI08_03690	COG0142	geranyltranstransferase activity
CTI08_03695	COG2315	Protein conserved in bacteria
CTI08_03710	COG1752	Esterase of the alpha-beta hydrolase superfamily
CTI08_03730	COG2194	sulfuric ester hydrolase activity
CTI08_03735	COG0745	RESPONSE REGULATOR receiver
CTI08_03740	COG0642	Histidine kinase
CTI08_03750	COG0004	ammonium transporteR
CTI08_03780	COG0525	valine-tRNA ligase activity
CTI08_03790	COG1028	Short-chain dehydrogenase reductase Sdr
CTI08_03800	COG0393	Putative heavy-metal-binding
CTI08_03805	COG0393	Putative heavy-metal-binding
CTI08_03810	COG1538	Outer membrane efflux protein
CTI08_03820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTI08_03825	COG0671	phosphoesterase, PA-phosphatase related
CTI08_03855	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CTI08_03870	COG1648	precorrin-2 dehydrogenase activity
CTI08_03870	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CTI08_03875	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CTI08_03880	COG1733	regulation of RNA biosynthetic process
CTI08_03890	COG0531	amino acid
CTI08_03905	COG0321	lipoyl(octanoyl) transferase activity
CTI08_03910	COG2921	Belongs to the UPF0250 family
CTI08_03950	COG2009	succinate dehydrogenase
CTI08_03955	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CTI08_03960	COG1053	succinate dehydrogenase
CTI08_03965	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CTI08_03990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTI08_04010	COG2354	Protein conserved in bacteria
CTI08_04015	COG2321	neutral zinc metallopeptidase
CTI08_04035	COG2843	Capsule synthesis protein
CTI08_04050	COG0589	response to stress
CTI08_04070	COG0505	Belongs to the CarA family
CTI08_04100	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CTI08_04155	COG0477	Major facilitator Superfamily
CTI08_04160	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CTI08_04180	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CTI08_04205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTI08_04210	COG0584	glycerophosphoryl diester phosphodiesterase
CTI08_04230	COG0741	lytic transglycosylase activity
CTI08_04255	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CTI08_04270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTI08_04295	COG0778	Nitroreductase
CTI08_04310	COG1929	Belongs to the glycerate kinase type-1 family
CTI08_04315	COG0243	molybdopterin cofactor binding
CTI08_04320	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CTI08_04325	COG3339	Conserved Protein
CTI08_04335	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CTI08_04350	COG1113	amino acid transport
CTI08_04360	COG0019	diaminopimelate decarboxylase activity
CTI08_04370	COG1280	lysine exporter protein (LysE YggA)
CTI08_04375	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CTI08_04405	COG0463	Glycosyl transferase, family 2
CTI08_04425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTI08_04455	COG4591	ABC-type transport system involved in lipoprotein release permease component
CTI08_04460	COG1136	(ABC) transporter
CTI08_04465	COG0658	competence protein
CTI08_04465	COG2333	competence protein COMEC
CTI08_04475	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CTI08_04475	COG0616	signal peptide processing
CTI08_04480	COG0596	Alpha beta hydrolase
CTI08_04485	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CTI08_04495	COG0628	permease
CTI08_04530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTI08_04550	COG0823	Involved in the tonB-independent uptake of proteins
CTI08_04570	COG0824	Thioesterase
CTI08_04575	COG1473	amidohydrolase
CTI08_04595	COG0047	phosphoribosylformylglycinamidine synthase activity
CTI08_04595	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CTI08_04600	COG2814	Major facilitator Superfamily
CTI08_04605	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CTI08_04610	COG1024	Enoyl-CoA hydratase
CTI08_04615	COG1051	belongs to the nudix hydrolase family
CTI08_04615	COG1056	cytidyltransferase-related domain
CTI08_04625	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CTI08_04640	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CTI08_04655	COG4625	pathogenesis
CTI08_04660	COG0583	DNA-binding transcription factor activity
CTI08_04665	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CTI08_04670	COG4208	sulfate ABC transporter
CTI08_04675	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CTI08_04685	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CTI08_04690	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CTI08_04695	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CTI08_04715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTI08_04730	COG0681	Belongs to the peptidase S26 family
CTI08_04745	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CTI08_04755	COG1381	Involved in DNA repair and RecF pathway recombination
CTI08_04760	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CTI08_04770	COG4221	oxidoreductase activity
CTI08_04820	COG0556	nucleotide-excision repair
CTI08_04875	COG2070	2-Nitropropane dioxygenase
CTI08_04905	COG1215	transferase activity, transferring glycosyl groups
CTI08_04920	COG0415	Belongs to the DNA photolyase family
CTI08_04930	COG1252	NADH dehydrogenase
CTI08_04935	COG1686	Belongs to the peptidase S11 family
CTI08_04950	COG1187	pseudouridine synthase activity
CTI08_04975	COG0477	Major facilitator Superfamily
CTI08_04980	COG0583	DNA-binding transcription factor activity
CTI08_04995	COG0612	Peptidase, M16
CTI08_05020	COG0352	thiamine-phosphate diphosphorylase activity
CTI08_05055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTI08_05070	COG1309	transcriptional regulator
CTI08_05080	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CTI08_05085	COG0076	glutamate decarboxylase activity
CTI08_05095	COG1522	sequence-specific DNA binding
CTI08_05100	COG3961	Belongs to the TPP enzyme family
CTI08_05105	COG1113	amino acid transport
CTI08_05110	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CTI08_05115	COG0573	inorganic phosphate transmembrane transporter activity
CTI08_05125	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CTI08_05130	COG0616	signal peptide processing
CTI08_05165	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CTI08_05170	COG1686	Belongs to the peptidase S11 family
CTI08_05195	COG0583	DNA-binding transcription factor activity
CTI08_05200	COG1067	ATP-dependent peptidase activity
CTI08_05245	COG1966	Carbon starvation protein
CTI08_05250	COG2879	small protein
CTI08_05285	COG2508	Transcriptional regulator
CTI08_05285	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CTI08_05305	COG1113	amino acid transport
CTI08_05310	COG0583	DNA-binding transcription factor activity
CTI08_05315	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTI08_05320	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTI08_05335	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTI08_05340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTI08_05340	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CTI08_05375	COG2814	Major facilitator Superfamily
CTI08_05380	COG4948	Mandelate Racemase Muconate Lactonizing
CTI08_05390	COG1309	transcriptional regulator
CTI08_05410	COG1741	Belongs to the pirin family
CTI08_05420	COG2964	Protein conserved in bacteria
CTI08_05535	COG2369	cell adhesion
CTI08_05540	COG4383	Mu-like prophage protein gp29
CTI08_05555	COG4373	Mu-like prophage FluMu protein gp28
CTI08_05590	COG0681	Belongs to the peptidase S26 family
CTI08_05615	COG3267	Type II secretory pathway component ExeA
CTI08_05615	COG3409	Peptidoglycan-binding domain 1 protein
CTI08_05645	COG0776	regulation of translation
CTI08_05695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTI08_05700	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTI08_05705	COG4605	iron ion homeostasis
CTI08_05710	COG4604	ABC transporter, ATP-binding protein
CTI08_05715	COG4607	ABC-type enterochelin transport system periplasmic component
CTI08_05720	COG4774	siderophore transport
CTI08_05730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTI08_05735	COG1021	2,3-dihydroxybenzoate-AMP ligase
CTI08_05740	COG3433	isochorismatase activity
CTI08_05740	COG1535	isochorismatase
CTI08_05755	COG1132	(ABC) transporter
CTI08_05765	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CTI08_05775	COG1169	isochorismate synthase
CTI08_05790	COG3739	integral membrane protein
CTI08_05835	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CTI08_05865	COG0308	aminopeptidase N
CTI08_05870	COG0512	Glutamine amidotransferase of anthranilate synthase
CTI08_06180	COG1598	PFAM Uncharacterised protein family UPF0150
CTI08_06190	COG0739	heme binding
CTI08_06190	COG0741	lytic transglycosylase activity
CTI08_06190	COG1196	nuclear chromosome segregation
CTI08_06240	COG2194	sulfuric ester hydrolase activity
CTI08_06275	COG0006	proline dipeptidase activity
CTI08_06280	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTI08_06285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTI08_06305	COG1279	arginine transmembrane transporter activity
CTI08_06310	COG0583	DNA-binding transcription factor activity
CTI08_06350	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CTI08_06355	COG1388	LysM domain
CTI08_06355	COG1388	LysM domain
CTI08_06355	COG0741	lytic transglycosylase activity
CTI08_06355	COG0741	lytic transglycosylase activity
CTI08_06365	COG4174	ABC transporter (Permease)
CTI08_06370	COG4239	(ABC) transporter, permease
CTI08_06375	COG4172	Belongs to the ABC transporter superfamily
CTI08_06395	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CTI08_06405	COG5001	Diguanylate cyclase
CTI08_06405	COG4251	negative regulation of phosphorylation
CTI08_06405	COG3706	GGDEF domain
CTI08_06405	COG2203	Gaf domain
CTI08_06415	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTI08_06415	COG1902	pentaerythritol trinitrate reductase activity
CTI08_06430	COG4269	membrane
CTI08_06455	COG3316	Transposase and inactivated derivatives
CTI08_06485	COG3316	Transposase and inactivated derivatives
CTI08_06495	COG0300	oxidoreductase activity
CTI08_06505	COG1309	transcriptional regulator
CTI08_06510	COG1741	Belongs to the pirin family
CTI08_06525	COG2072	flavoprotein involved in K transport
CTI08_06535	COG2252	PERMEase
CTI08_06540	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CTI08_06545	COG3038	cytochrome b561
CTI08_06555	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CTI08_06620	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CTI08_06625	COG4197	protein conserved in bacteria, prophage-related
CTI08_06710	COG5410	chromosome segregation
CTI08_06715	COG3567	Phage-associated protein, HI1409 family
CTI08_06730	COG3566	protein conserved in bacteria
CTI08_06905	COG0477	Major facilitator Superfamily
CTI08_06910	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTI08_06935	COG0531	amino acid
CTI08_06940	COG2040	homocysteine
CTI08_06965	COG1309	transcriptional regulator
CTI08_06970	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTI08_06975	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTI08_06985	COG1607	acyl-coa hydrolase
CTI08_06995	COG0523	cobalamin synthesis protein
CTI08_07005	COG4681	YaeQ
CTI08_07015	COG0726	polysaccharide deacetylase
CTI08_07015	COG1649	PFAM Uncharacterised BCR, COG1649
CTI08_07020	COG1215	transferase activity, transferring glycosyl groups
CTI08_07030	COG1024	Enoyl-CoA hydratase
CTI08_07045	COG1414	Transcriptional regulator
CTI08_07065	COG1028	Short-chain dehydrogenase reductase Sdr
CTI08_07075	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTI08_07080	COG2271	Major facilitator Superfamily
CTI08_07090	COG2267	carboxylic ester hydrolase activity
CTI08_07095	COG1028	Short-chain dehydrogenase reductase Sdr
CTI08_07110	COG0028	Belongs to the TPP enzyme family
CTI08_07120	COG0477	Major facilitator Superfamily
CTI08_07125	COG0242	peptide deformylase activity
CTI08_07130	COG2066	Belongs to the glutaminase family
CTI08_07135	COG2207	Transcriptional regulator
CTI08_07140	COG2223	nitrite transmembrane transporter activity
CTI08_07160	COG0583	DNA-binding transcription factor activity
CTI08_07165	COG1028	Short-chain dehydrogenase reductase Sdr
CTI08_07170	COG2271	Major facilitator Superfamily
CTI08_07175	COG3959	Transketolase, thiamine diphosphate binding domain
CTI08_07180	COG3958	Transketolase
CTI08_07190	COG0306	phosphate transporter
CTI08_07210	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CTI08_07255	COG4181	ATPase activity
CTI08_07260	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CTI08_07290	COG0583	DNA-binding transcription factor activity
CTI08_07300	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTI08_07305	COG1773	rubredoxin
CTI08_07355	COG2851	Citrate transporter
CTI08_07365	COG1253	flavin adenine dinucleotide binding
CTI08_07405	COG0804	urea catabolic process
CTI08_07415	COG0830	nickel cation binding
CTI08_07430	COG0742	ribosomal rna small subunit methyltransferase
CTI08_07435	COG0768	penicillin binding
CTI08_07460	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CTI08_07465	COG2878	Part of a membrane complex involved in electron transport
CTI08_07470	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CTI08_07480	COG3384	dioxygenase
CTI08_07505	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CTI08_07680	COG5410	chromosome segregation
CTI08_08075	COG0739	heme binding
CTI08_08120	COG0582	viral genome integration into host DNA
CTI08_08130	COG3104	oligopeptide transport
CTI08_08145	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CTI08_08180	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CTI08_08185	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CTI08_08190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTI08_08210	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CTI08_08215	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CTI08_08220	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CTI08_08235	COG1960	acyl-CoA dehydrogenase activity
CTI08_08240	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CTI08_08245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTI08_08255	COG2223	nitrite transmembrane transporter activity
CTI08_08265	COG0024	Methionine aminopeptidase
CTI08_08270	COG0052	Belongs to the universal ribosomal protein uS2 family
CTI08_08285	COG2207	Transcriptional regulator
CTI08_08310	COG2951	lytic endotransglycosylase activity
CTI08_08315	COG0772	Belongs to the SEDS family
CTI08_08330	COG0842	Transport permease protein
CTI08_08335	COG1131	(ABC) transporter
CTI08_08370	COG1538	Outer membrane efflux protein
CTI08_08380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTI08_08395	COG4215	(ABC) transporter
CTI08_08400	COG4160	amino acid transport
CTI08_08405	COG4598	ABC transporter
CTI08_08415	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTI08_08425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTI08_08440	COG1720	tRNA m6t6A37 methyltransferase activity
CTI08_08460	COG0745	RESPONSE REGULATOR receiver
CTI08_08465	COG0642	Histidine kinase
CTI08_08475	COG0494	nUDIX hydrolase
CTI08_08485	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CTI08_08490	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CTI08_08495	COG3139	Protein of unknown function (DUF1315)
CTI08_08500	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CTI08_08510	COG1301	dicarboxylic acid transport
CTI08_08515	COG1960	acyl-CoA dehydrogenase activity
CTI08_08520	COG2819	hydrolase of the alpha beta superfamily
CTI08_08530	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CTI08_08540	COG2195	Cleaves the N-terminal amino acid of tripeptides
CTI08_08545	COG1234	tRNA 3'-trailer cleavage
CTI08_08575	COG2363	Small membrane protein
CTI08_08595	COG0513	Belongs to the DEAD box helicase family
CTI08_08605	COG0778	Nitroreductase
CTI08_08635	COG1286	toxin biosynthetic process
CTI08_08660	COG4783	chaperone-mediated protein folding
CTI08_08665	COG1610	YqeY-like protein
CTI08_08670	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CTI08_08775	COG3111	PFAM Bacterial OB fold (BOF) protein
CTI08_08800	COG3243	poly(R)-hydroxyalkanoic acid synthase
CTI08_08805	COG0786	glutamate:sodium symporter activity
CTI08_08815	COG2186	Transcriptional regulator
CTI08_08865	COG0477	Major facilitator Superfamily
CTI08_08895	COG2985	domain, Protein
CTI08_08905	COG2995	paraquat-inducible protein a
CTI08_08910	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CTI08_08910	COG3008	intermembrane lipid transfer
CTI08_08920	COG1794	racemase activity, acting on amino acids and derivatives
CTI08_08950	COG1301	dicarboxylic acid transport
CTI08_08960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTI08_08965	COG2011	ABC-type metal ion transport system permease component
CTI08_08970	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CTI08_08975	COG1464	Belongs to the NlpA lipoprotein family
CTI08_08980	COG0151	Belongs to the GarS family
CTI08_08985	COG0138	bifunctional purine biosynthesis protein purh
CTI08_08990	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CTI08_09020	COG2308	Evidence 4 Homologs of previously reported genes of
CTI08_09030	COG1305	Transglutaminase-like
CTI08_09040	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CTI08_09045	COG0305	Participates in initiation and elongation during chromosome replication
CTI08_09070	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CTI08_09080	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CTI08_09085	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CTI08_09110	COG0726	polysaccharide deacetylase
CTI08_09110	COG1649	PFAM Uncharacterised BCR, COG1649
CTI08_09115	COG1215	transferase activity, transferring glycosyl groups
CTI08_09120	COG3658	cytochrome
CTI08_09130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTI08_09150	COG0583	DNA-binding transcription factor activity
CTI08_09170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTI08_09175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTI08_09190	COG1960	acyl-CoA dehydrogenase activity
CTI08_09195	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTI08_09200	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTI08_09225	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CTI08_09230	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CTI08_09240	COG2205	protein histidine kinase activity
CTI08_09245	COG0745	RESPONSE REGULATOR receiver
CTI08_09250	COG0174	glutamine synthetase
CTI08_09270	COG0729	surface antigen
CTI08_09300	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CTI08_09305	COG2814	Major facilitator Superfamily
CTI08_09320	COG0583	DNA-binding transcription factor activity
CTI08_09335	COG1187	pseudouridine synthase activity
CTI08_09355	COG0802	atpase or kinase
CTI08_09360	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CTI08_09370	COG1923	regulation of RNA biosynthetic process
CTI08_09375	COG0697	spore germination
CTI08_09390	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTI08_09405	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CTI08_09405	COG0519	Catalyzes the synthesis of GMP from XMP
CTI08_09410	COG4302	ethanolamine ammonia-lyase activity
CTI08_09415	COG4303	Ethanolamine ammonia lyase large subunit
CTI08_09420	COG0531	amino acid
CTI08_09440	COG1454	alcohol dehydrogenase
CTI08_09445	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CTI08_09455	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CTI08_09475	COG0308	aminopeptidase N
CTI08_09485	COG4221	oxidoreductase activity
CTI08_09495	COG1605	Chorismate mutase
CTI08_09515	COG1309	transcriptional regulator
CTI08_09525	COG0668	transmembrane transport
CTI08_09555	COG4773	Receptor
CTI08_09575	COG0488	(ABC) transporter
CTI08_09580	COG0589	response to stress
CTI08_09600	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CTI08_09610	COG3135	benzoate transporter
CTI08_09615	COG1522	sequence-specific DNA binding
CTI08_09630	COG0583	DNA-binding transcription factor activity
CTI08_09640	COG0183	Belongs to the thiolase family
CTI08_09645	COG1028	Short-chain dehydrogenase reductase Sdr
CTI08_09670	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CTI08_09680	COG0824	Thioesterase
CTI08_09685	COG1454	alcohol dehydrogenase
CTI08_09695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CTI08_09715	COG0069	glutamate synthase activity
CTI08_09735	COG2814	Major facilitator Superfamily
CTI08_09750	COG0511	ligase activity, forming carbon-carbon bonds
CTI08_09765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTI08_09765	COG1116	anion transmembrane transporter activity
CTI08_09770	COG0745	RESPONSE REGULATOR receiver
CTI08_09780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTI08_09780	COG2146	nitrite reductase [NAD(P)H] activity
CTI08_09785	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTI08_09790	COG0243	molybdopterin cofactor binding
CTI08_09800	COG0243	molybdopterin cofactor binding
CTI08_09805	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CTI08_09820	COG0521	Mo-molybdopterin cofactor biosynthetic process
CTI08_09820	COG0315	cyclic pyranopterin monophosphate synthase activity
CTI08_09825	COG0303	'Molybdopterin
CTI08_09835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTI08_09840	COG0697	spore germination
CTI08_09860	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CTI08_09865	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CTI08_09925	COG2204	response regulator
CTI08_09930	COG3852	Histidine kinase
CTI08_09950	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CTI08_09955	COG0575	Belongs to the CDS family
CTI08_09990	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTI08_10005	COG2137	regulation of response to DNA damage stimulus
CTI08_10015	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CTI08_10020	COG1011	Hydrolase
CTI08_10045	COG1522	sequence-specific DNA binding
CTI08_10055	COG1113	amino acid transport
CTI08_10075	COG0659	secondary active sulfate transmembrane transporter activity
CTI08_10080	COG2135	peptidase activity
CTI08_10095	COG5001	Diguanylate cyclase
CTI08_10095	COG3300	MHYT domain
CTI08_10115	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTI08_10115	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTI08_10115	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CTI08_10120	COG1105	Belongs to the carbohydrate kinase PfkB family
CTI08_10125	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTI08_10125	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CTI08_10155	COG0024	Methionine aminopeptidase
CTI08_10160	COG0583	DNA-binding transcription factor activity
CTI08_10170	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CTI08_10175	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CTI08_10180	COG0517	IMP dehydrogenase activity
CTI08_10180	COG0516	GMP reductase activity
CTI08_10205	COG0552	protein localization to endoplasmic reticulum
CTI08_10215	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CTI08_10235	COG4890	Cyd operon protein YbgT
CTI08_10240	COG1294	oxidase, subunit
CTI08_10255	COG1585	Membrane protein implicated in regulation of membrane protease activity
CTI08_10265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CTI08_10270	COG4774	siderophore transport
CTI08_10285	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CTI08_10290	COG0569	domain protein
CTI08_10295	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CTI08_10325	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CTI08_10330	COG0542	response to heat
CTI08_10340	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CTI08_10355	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTI08_10355	COG1902	pentaerythritol trinitrate reductase activity
CTI08_10400	COG2323	membrane
CTI08_10405	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CTI08_10415	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CTI08_10420	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTI08_10425	COG0183	Belongs to the thiolase family
CTI08_10430	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CTI08_10435	COG0596	Alpha beta hydrolase
CTI08_10440	COG2271	Major facilitator Superfamily
CTI08_10445	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTI08_10450	COG3485	protocatechuate 3,4-dioxygenase
CTI08_10455	COG3485	protocatechuate 3,4-dioxygenase
CTI08_10460	COG0710	3-dehydroquinate dehydratase activity
CTI08_10465	COG3420	alginic acid biosynthetic process
CTI08_10470	COG3659	wide pore channel activity
CTI08_10475	COG4993	Dehydrogenase
CTI08_10485	COG2391	methyltransferase activity
CTI08_10500	COG1414	Transcriptional regulator
CTI08_10505	COG0583	DNA-binding transcription factor activity
CTI08_10510	COG1960	acyl-CoA dehydrogenase activity
CTI08_10535	COG2814	Major facilitator Superfamily
CTI08_10545	COG0154	amidase activity
CTI08_10565	COG4638	Rieske (2fe-2S)
CTI08_10575	COG1028	Short-chain dehydrogenase reductase Sdr
CTI08_10585	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTI08_10595	COG3733	amine oxidase
CTI08_10605	COG1012	belongs to the aldehyde dehydrogenase family
CTI08_10615	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTI08_10620	COG0183	Belongs to the thiolase family
CTI08_10625	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTI08_10640	COG4829	muconolactone delta-isomerase
CTI08_10650	COG0583	DNA-binding transcription factor activity
CTI08_10660	COG2186	Transcriptional regulator
CTI08_10680	COG1012	belongs to the aldehyde dehydrogenase family
CTI08_10700	COG1960	acyl-CoA dehydrogenase activity
CTI08_10705	COG1028	Short-chain dehydrogenase reductase Sdr
CTI08_10710	COG3829	transcription factor binding
CTI08_10720	COG3162	membrane
CTI08_10735	COG1012	belongs to the aldehyde dehydrogenase family
CTI08_10750	COG0753	catalase activity
CTI08_10775	COG1846	Transcriptional regulator
CTI08_10780	COG1902	pentaerythritol trinitrate reductase activity
CTI08_10780	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTI08_10790	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CTI08_10820	COG1309	transcriptional regulator
CTI08_10830	COG1335	isochorismatase
CTI08_10835	COG0583	DNA-binding transcription factor activity
CTI08_10845	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CTI08_10845	COG0475	glutathione-regulated potassium exporter activity
CTI08_10855	COG1473	amidohydrolase
CTI08_10870	COG2831	hemolysin activation secretion protein
CTI08_10875	COG3210	domain, Protein
CTI08_10920	COG0583	DNA-binding transcription factor activity
CTI08_10945	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CTI08_10950	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CTI08_10970	COG1566	PFAM secretion protein HlyD family protein
CTI08_10985	COG1012	belongs to the aldehyde dehydrogenase family
CTI08_10990	COG0129	dihydroxy-acid dehydratase activity
CTI08_11000	COG0583	DNA-binding transcription factor activity
CTI08_11005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CTI08_11015	COG2084	Dehydrogenase
CTI08_11020	COG2207	Transcriptional regulator
CTI08_11035	COG1064	alcohol dehydrogenase
CTI08_11050	COG1120	ATPase activity
CTI08_11070	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CTI08_11195	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CTI08_11245	COG1028	Short-chain dehydrogenase reductase Sdr
CTI08_11275	COG2205	protein histidine kinase activity
CTI08_11280	COG0745	RESPONSE REGULATOR receiver
CTI08_11285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTI08_11290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTI08_11295	COG1538	Outer membrane efflux protein
CTI08_11305	COG2072	flavoprotein involved in K transport
CTI08_11325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTI08_11370	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CTI08_11380	COG0753	catalase activity
CTI08_11395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CTI08_11460	COG1535	isochorismatase
CTI08_11460	COG3433	isochorismatase activity
CTI08_11465	COG1028	Short-chain dehydrogenase reductase Sdr
CTI08_11470	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CTI08_11475	COG4149	molybdate abc transporter
CTI08_11480	COG0725	ABC transporter, periplasmic molybdate-binding protein
CTI08_11490	COG4638	Rieske (2fe-2S)
CTI08_11495	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CTI08_11500	COG0543	2 iron, 2 sulfur cluster binding
CTI08_11500	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTI08_11515	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTI08_11525	COG1028	Short-chain dehydrogenase reductase Sdr
CTI08_11530	COG0412	Dienelactone hydrolase
CTI08_11540	COG2207	Transcriptional regulator
CTI08_11545	COG1028	Short-chain dehydrogenase reductase Sdr
CTI08_11550	COG2610	gluconate transmembrane transporter activity
CTI08_11560	COG0583	DNA-binding transcription factor activity
CTI08_11570	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTI08_11575	COG2031	fatty acid transporter
CTI08_11580	COG0183	Belongs to the thiolase family
CTI08_11585	COG0583	DNA-binding transcription factor activity
CTI08_11590	COG0583	DNA-binding transcription factor activity
CTI08_11605	COG1027	Aspartate ammonia-lyase
CTI08_11615	COG0477	Major facilitator Superfamily
CTI08_11635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTI08_11640	COG4521	taurine ABC transporter
CTI08_11665	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CTI08_11670	COG1733	regulation of RNA biosynthetic process
CTI08_11675	COG2207	Transcriptional regulator
CTI08_11675	COG3708	Transcriptional regulator
CTI08_11690	COG0730	response to heat
CTI08_11700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTI08_11700	COG3453	Protein conserved in bacteria
CTI08_11710	COG3781	membrane
CTI08_11715	COG1063	alcohol dehydrogenase
CTI08_11725	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTI08_11730	COG0508	dehydrogenase complex catalyzes the overall conversion of
CTI08_11735	COG0022	dehydrogenase e1 component
CTI08_11740	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CTI08_11745	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CTI08_11760	COG3706	GGDEF domain
CTI08_11775	COG0133	tryptophan synthase activity
CTI08_11785	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CTI08_11820	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CTI08_11845	COG2226	methyltransferase
CTI08_11900	COG0842	Transport permease protein
CTI08_11905	COG0842	Transport permease protein
CTI08_11910	COG1131	(ABC) transporter
CTI08_11925	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTI08_11930	COG4773	Receptor
CTI08_11950	COG0730	response to heat
CTI08_11955	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CTI08_11975	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CTI08_12040	COG4264	IucA IucC family
CTI08_12045	COG4264	IucA IucC family
CTI08_12050	COG2814	Major facilitator Superfamily
CTI08_12075	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CTI08_12090	COG1960	acyl-CoA dehydrogenase activity
CTI08_12095	COG1960	acyl-CoA dehydrogenase activity
CTI08_12100	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTI08_12105	COG2207	Transcriptional regulator
CTI08_12110	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CTI08_12115	COG0776	regulation of translation
CTI08_12140	COG0822	iron-sulfur transferase activity
CTI08_12145	COG0316	Belongs to the HesB IscA family
CTI08_12175	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CTI08_12195	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CTI08_12200	COG0702	epimerase
CTI08_12235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTI08_12245	COG0339	signal peptide processing
CTI08_12300	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CTI08_12415	COG4695	Portal protein
CTI08_12500	COG0305	Participates in initiation and elongation during chromosome replication
CTI08_12560	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CTI08_12590	COG0776	regulation of translation
CTI08_12610	COG0590	tRNA wobble adenosine to inosine editing
CTI08_12640	COG2165	general secretion pathway protein
CTI08_12655	COG0084	hydrolase, TatD family'
CTI08_12675	COG1663	tetraacyldisaccharide 4'-kinase activity
CTI08_12680	COG1132	(ABC) transporter
CTI08_12690	COG0811	peptide transport
CTI08_12695	COG1475	DNA binding
CTI08_12700	COG1192	Involved in chromosome partitioning
CTI08_12710	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CTI08_12725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CTI08_12730	COG0191	fructose-bisphosphate aldolase activity
CTI08_12750	COG0424	maF-like protein
CTI08_12755	COG2850	peptidyl-arginine hydroxylation
CTI08_12765	COG0640	Transcriptional regulator
CTI08_12775	COG3619	membrane
CTI08_12780	COG3122	Protein conserved in bacteria
CTI08_12785	COG1132	(ABC) transporter
CTI08_12805	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CTI08_12810	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CTI08_12820	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CTI08_12820	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CTI08_12820	COG0506	proline dehydrogenase activity
CTI08_12825	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CTI08_12840	COG3698	Phosphodiester glycosidase
CTI08_12850	COG2353	YceI-like domain
CTI08_12860	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CTI08_12905	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CTI08_12905	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CTI08_12930	COG3539	Fimbrial protein
CTI08_12935	COG3121	Chaperone
CTI08_12965	COG0697	spore germination
CTI08_12975	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CTI08_12985	COG0583	DNA-binding transcription factor activity
CTI08_13005	COG1309	transcriptional regulator
CTI08_13020	COG1522	sequence-specific DNA binding
CTI08_13030	COG1126	abc transporter atp-binding protein
CTI08_13035	COG0765	amino acid transport
CTI08_13040	COG0765	amino acid transport
CTI08_13070	COG1464	Belongs to the NlpA lipoprotein family
CTI08_13080	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CTI08_13085	COG2011	ABC-type metal ion transport system permease component
CTI08_13090	COG0012	GTP binding
CTI08_13115	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CTI08_13155	COG0386	Belongs to the glutathione peroxidase family
CTI08_13165	COG0436	Aminotransferase
CTI08_13205	COG3634	alkyl hydroperoxide reductase activity
CTI08_13220	COG0583	DNA-binding transcription factor activity
CTI08_13225	COG0798	PFAM Bile acid sodium symporter
CTI08_13230	COG0640	Transcriptional regulator
CTI08_13245	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CTI08_13255	COG0583	DNA-binding transcription factor activity
CTI08_13265	COG1953	Uracil, thiamine, allantoin
CTI08_13275	COG2175	clavaminate synthase activity
CTI08_13280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTI08_13285	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CTI08_13290	COG4521	taurine ABC transporter
CTI08_13330	COG1271	oxidase subunit
CTI08_13335	COG1294	oxidase, subunit
CTI08_13345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTI08_13365	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CTI08_13385	COG3052	prosthetic group binding
CTI08_13390	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CTI08_13400	COG2814	Major facilitator Superfamily
CTI08_13420	COG1346	cytolysis
CTI08_13430	COG0583	DNA-binding transcription factor activity
CTI08_13435	COG0625	glutathione transferase activity
CTI08_13440	COG0625	glutathione transferase activity
CTI08_13445	COG0583	DNA-binding transcription factor activity
CTI08_13460	COG1045	serine acetyltransferase
CTI08_13465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CTI08_13470	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CTI08_13475	COG1280	lysine exporter protein (LysE YggA)
CTI08_13490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTI08_13495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTI08_13500	COG1126	abc transporter atp-binding protein
CTI08_13505	COG0765	amino acid transport
CTI08_13510	COG0765	amino acid transport
CTI08_13530	COG0784	Response regulator, receiver
CTI08_13530	COG2205	protein histidine kinase activity
CTI08_13550	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CTI08_13570	COG1028	Short-chain dehydrogenase reductase Sdr
CTI08_13615	COG0583	DNA-binding transcription factor activity
CTI08_13635	COG0318	PFAM AMP-dependent synthetase and ligase
CTI08_13640	COG1309	transcriptional regulator
CTI08_13645	COG1960	acyl-CoA dehydrogenase activity
CTI08_13650	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CTI08_13655	COG1024	Enoyl-CoA hydratase
CTI08_13670	COG0583	DNA-binding transcription factor activity
CTI08_13685	COG1960	acyl-CoA dehydrogenase activity
CTI08_13695	COG2814	Major facilitator Superfamily
CTI08_13705	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTI08_13710	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CTI08_13715	COG2814	Major facilitator Superfamily
CTI08_13720	COG1960	acyl-CoA dehydrogenase activity
CTI08_13725	COG1024	Enoyl-CoA hydratase
CTI08_13730	COG1028	Short-chain dehydrogenase reductase Sdr
CTI08_13740	COG0183	Belongs to the thiolase family
CTI08_13750	COG2814	Major facilitator Superfamily
CTI08_13760	COG1024	Enoyl-CoA hydratase
CTI08_13775	COG1960	acyl-CoA dehydrogenase activity
CTI08_13780	COG2814	Major facilitator Superfamily
CTI08_13785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CTI08_13790	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CTI08_13805	COG3842	ATPase activity
CTI08_13810	COG1840	ABC-type Fe3 transport system, periplasmic component
CTI08_13820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTI08_13825	COG1414	Transcriptional regulator
CTI08_13835	COG0583	DNA-binding transcription factor activity
CTI08_13840	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTI08_13845	COG1012	belongs to the aldehyde dehydrogenase family
CTI08_13855	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CTI08_13865	COG1012	belongs to the aldehyde dehydrogenase family
CTI08_13870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTI08_13875	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTI08_13880	COG2267	carboxylic ester hydrolase activity
CTI08_13900	COG3038	cytochrome b561
CTI08_13905	COG0753	catalase activity
CTI08_13945	COG2050	protein possibly involved in aromatic compounds catabolism
CTI08_13955	COG3327	negative regulation of DNA-templated transcription, initiation
CTI08_13960	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CTI08_13965	COG0183	Belongs to the thiolase family
CTI08_13970	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTI08_13975	COG1024	Enoyl-CoA hydratase
CTI08_13980	COG1024	Enoyl-CoA hydratase
CTI08_13985	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTI08_13990	COG2151	metal-sulfur cluster biosynthetic enzyme
CTI08_13995	COG3396	Phenylacetate-CoA oxygenase
CTI08_14000	COG3460	Phenylacetate-CoA oxygenase
CTI08_14005	COG3396	Phenylacetate-CoA oxygenase
CTI08_14010	COG2030	dehydratase
CTI08_14010	COG1012	belongs to the aldehyde dehydrogenase family
CTI08_14015	COG1760	l-serine dehydratase
CTI08_14020	COG0531	amino acid
CTI08_14025	COG1012	belongs to the aldehyde dehydrogenase family
CTI08_14050	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTI08_14060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTI08_14080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTI08_14095	COG0789	Transcriptional regulator
CTI08_14105	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CTI08_14120	COG2807	transmembrane transport
CTI08_14125	COG0590	tRNA wobble adenosine to inosine editing
CTI08_14135	COG0583	DNA-binding transcription factor activity
CTI08_14175	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CTI08_14175	COG2885	chlorophyll binding
CTI08_14245	COG1116	anion transmembrane transporter activity
CTI08_14250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTI08_14260	COG0864	Transcriptional regulator
CTI08_14280	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTI08_14285	COG0439	Biotin carboxylase
CTI08_14300	COG1063	alcohol dehydrogenase
CTI08_14310	COG1309	transcriptional regulator
CTI08_14335	COG0038	chloride channel
CTI08_14340	COG4770	biotin carboxylase activity
CTI08_14360	COG1914	H( )-stimulated, divalent metal cation uptake system
CTI08_14365	COG0583	DNA-binding transcription factor activity
CTI08_14380	COG3209	COG3209 Rhs family protein
CTI08_14385	COG3501	Rhs element vgr protein
CTI08_14420	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTI08_14445	COG2814	Major facilitator Superfamily
CTI08_14460	COG1560	Kdo2-lipid A biosynthetic process
CTI08_14470	COG5006	permease, DMT superfamily
CTI08_14475	COG1522	sequence-specific DNA binding
CTI08_14490	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CTI08_14530	COG1538	Outer membrane efflux protein
CTI08_14540	COG1137	ATPase activity
CTI08_14545	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CTI08_14555	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CTI08_14560	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CTI08_14560	COG0517	IMP dehydrogenase activity
CTI08_14595	COG1733	regulation of RNA biosynthetic process
CTI08_14600	COG2814	Major facilitator Superfamily
CTI08_14640	COG1278	Cold shock
CTI08_14645	COG1280	lysine exporter protein (LysE YggA)
CTI08_14680	COG1570	exodeoxyribonuclease VII activity
CTI08_14735	COG0583	DNA-binding transcription factor activity
CTI08_14740	COG4638	Rieske (2fe-2S)
CTI08_14745	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CTI08_14750	COG0633	Ferredoxin
CTI08_14750	COG0543	2 iron, 2 sulfur cluster binding
CTI08_14755	COG1028	Short-chain dehydrogenase reductase Sdr
CTI08_14760	COG3135	benzoate transporter
CTI08_14765	COG2814	Major facilitator Superfamily
CTI08_14780	COG1643	Atp-dependent helicase
CTI08_14785	COG0450	alkyl hydroperoxide reductase
CTI08_14795	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CTI08_14805	COG3634	alkyl hydroperoxide reductase activity
CTI08_14825	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CTI08_14830	COG0625	glutathione transferase activity
CTI08_14840	COG2885	chlorophyll binding
CTI08_14890	COG1765	OsmC-like protein
CTI08_14905	COG0667	Aldo Keto reductase
CTI08_14920	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CTI08_14930	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CTI08_14940	COG0582	viral genome integration into host DNA
CTI08_15100	COG0405	Gamma-glutamyltransferase
CTI08_15105	COG2814	Major facilitator Superfamily
CTI08_15115	COG2050	protein possibly involved in aromatic compounds catabolism
CTI08_15130	COG1090	epimerase
CTI08_15150	COG0420	3'-5' exonuclease activity
CTI08_15175	COG0735	belongs to the Fur family
CTI08_15180	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CTI08_15205	COG0121	glutamine amidotransferase
CTI08_15220	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CTI08_15230	COG0210	DNA helicase
CTI08_15235	COG2885	chlorophyll binding
CTI08_15240	COG0204	Acyl-transferase
CTI08_15255	COG2894	cell division
CTI08_15275	COG1280	lysine exporter protein (LysE YggA)
CTI08_15280	COG1674	ftsk spoiiie
CTI08_15280	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CTI08_15285	COG0492	ferredoxin-NADP+ reductase activity
CTI08_15290	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CTI08_15300	COG0456	acetyltransferase
CTI08_15360	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CTI08_15360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CTI08_15380	COG1012	belongs to the aldehyde dehydrogenase family
CTI08_15400	COG0473	3-isopropylmalate dehydrogenase activity
CTI08_15405	COG0583	DNA-binding transcription factor activity
CTI08_15425	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTI08_15450	COG0564	pseudouridine synthase activity
CTI08_15460	COG0358	DNA primase activity
CTI08_15475	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CTI08_15505	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CTI08_15535	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CTI08_15545	COG0352	thiamine-phosphate diphosphorylase activity
CTI08_15545	COG0351	phosphomethylpyrimidine kinase
CTI08_15545	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CTI08_15550	COG1652	LysM domain
CTI08_15575	COG1399	metal-binding, possibly nucleic acid-binding protein
CTI08_15580	COG3101	peptidyl-lysine hydroxylation
CTI08_15585	COG0009	L-threonylcarbamoyladenylate synthase
CTI08_15590	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CTI08_15595	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CTI08_15610	COG4106	trans-aconitate 2-methyltransferase activity
CTI08_15625	COG0596	Alpha beta hydrolase
CTI08_15625	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTI08_15625	COG2226	methyltransferase
CTI08_15630	COG1877	trehalose-phosphatase activity
CTI08_15635	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CTI08_15640	COG2223	nitrite transmembrane transporter activity
CTI08_15660	COG1196	nuclear chromosome segregation
CTI08_15670	COG0730	response to heat
CTI08_15685	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CTI08_15695	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CTI08_15750	COG0489	protein tyrosine kinase activity
CTI08_15760	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTI08_15760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTI08_15790	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CTI08_15795	COG2081	HI0933 family
CTI08_15805	COG0668	transmembrane transport
CTI08_15825	COG0583	DNA-binding transcription factor activity
CTI08_15845	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTI08_15850	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CTI08_15880	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CTI08_15915	COG2205	protein histidine kinase activity
CTI08_15920	COG0745	RESPONSE REGULATOR receiver
CTI08_15940	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CTI08_15950	COG2205	protein histidine kinase activity
CTI08_16035	COG4993	Dehydrogenase
CTI08_16055	COG0384	phenazine biosynthesis protein PhzF
CTI08_16085	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTI08_16090	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CTI08_16100	COG0583	DNA-binding transcription factor activity
CTI08_16120	COG1473	amidohydrolase
CTI08_16130	COG0583	DNA-binding transcription factor activity
CTI08_16150	COG0583	DNA-binding transcription factor activity
CTI08_16155	COG1053	succinate dehydrogenase
CTI08_16165	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CTI08_16170	COG2814	Major facilitator Superfamily
CTI08_16175	COG1960	acyl-CoA dehydrogenase activity
CTI08_16180	COG0583	DNA-binding transcription factor activity
CTI08_16185	COG1063	alcohol dehydrogenase
CTI08_16215	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CTI08_16220	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CTI08_16225	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CTI08_16240	COG3667	copper resistance
CTI08_16245	COG2132	Multicopper oxidase
CTI08_16255	COG0561	phosphatase activity
CTI08_16260	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CTI08_16285	COG1214	PFAM Peptidase M22, glycoprotease
CTI08_16335	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CTI08_16345	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CTI08_16350	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CTI08_16355	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CTI08_16415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CTI08_16425	COG1846	Transcriptional regulator
CTI08_16430	COG1764	response to oxidative stress
CTI08_16470	COG0037	tRNA processing
CTI08_16480	COG0248	Ppx GppA phosphatase
CTI08_16510	COG0072	phenylalanine-tRNA ligase activity
CTI08_16535	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CTI08_16550	COG1238	metal cluster binding
CTI08_16555	COG0625	glutathione transferase activity
CTI08_16575	COG0318	PFAM AMP-dependent synthetase and ligase
CTI08_16580	COG3028	Belongs to the UPF0307 family
CTI08_16585	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTI08_16605	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CTI08_16610	COG0617	tRNA 3'-terminal CCA addition
CTI08_16615	COG1555	photosystem II stabilization
CTI08_16620	COG3956	TIGRFAM MazG family protein
CTI08_16645	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CTI08_16665	COG5002	protein histidine kinase activity
CTI08_16665	COG0784	Response regulator, receiver
CTI08_16665	COG2205	protein histidine kinase activity
CTI08_16670	COG1024	Enoyl-CoA hydratase
CTI08_16675	COG2084	Dehydrogenase
CTI08_16680	COG3622	Belongs to the hyi family
CTI08_16695	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CTI08_16700	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CTI08_16705	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CTI08_16710	COG0697	spore germination
CTI08_16720	COG2814	Major facilitator Superfamily
CTI08_16725	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CTI08_16735	COG0583	DNA-binding transcription factor activity
CTI08_16745	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CTI08_16760	COG0084	hydrolase, TatD family'
CTI08_16775	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CTI08_16810	COG0440	acetolactate synthase activity
CTI08_16815	COG0028	Belongs to the TPP enzyme family
CTI08_16840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTI08_16845	COG0577	efflux transmembrane transporter activity
CTI08_16845	COG1136	(ABC) transporter
CTI08_16850	COG1538	Outer membrane efflux protein
CTI08_16865	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CTI08_16870	COG1162	GTPase activity
CTI08_16880	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CTI08_16900	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CTI08_16905	COG1028	Short-chain dehydrogenase reductase Sdr
CTI08_16945	COG2986	histidine ammonia-lyase
CTI08_16960	COG0318	PFAM AMP-dependent synthetase and ligase
CTI08_16970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CTI08_16975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CTI08_17015	COG1426	Protein conserved in bacteria
CTI08_17050	COG0793	Belongs to the peptidase S41A family
CTI08_17065	COG2267	carboxylic ester hydrolase activity
CTI08_17075	COG1012	belongs to the aldehyde dehydrogenase family
CTI08_17080	COG3265	gluconokinase activity
CTI08_17090	COG0800	Aldolase
CTI08_17100	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CTI08_17105	COG0280	phosphate acetyltransferase
CTI08_17105	COG0857	belongs to the CobB CobQ family
CTI08_17110	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CTI08_17110	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CTI08_17130	COG0740	serine-type endopeptidase activity
CTI08_17140	COG4774	siderophore transport
CTI08_17150	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CTI08_17160	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTI08_17160	COG2813	Specifically methylates the guanine in position
CTI08_17265	COG0788	formyltetrahydrofolate deformylase activity
CTI08_17280	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CTI08_17285	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CTI08_17290	COG4651	solute:proton antiporter activity
CTI08_17290	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CTI08_17310	COG0724	RNA recognition motif
CTI08_17315	COG0210	DNA helicase
CTI08_17340	COG1733	regulation of RNA biosynthetic process
CTI08_17360	COG1280	lysine exporter protein (LysE YggA)
CTI08_17365	COG1560	Kdo2-lipid A biosynthetic process
CTI08_17375	COG1301	dicarboxylic acid transport
CTI08_17445	COG0473	3-isopropylmalate dehydrogenase activity
CTI08_17510	COG0583	DNA-binding transcription factor activity
CTI08_17520	COG0625	glutathione transferase activity
CTI08_17525	COG2378	regulation of single-species biofilm formation
CTI08_17530	COG0546	phosphoglycolate phosphatase activity
CTI08_17545	COG1530	ribonuclease E activity
CTI08_17565	COG0583	DNA-binding transcription factor activity
CTI08_17570	COG4221	oxidoreductase activity
CTI08_17575	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CTI08_17585	COG0534	Mate efflux family protein
CTI08_17600	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CTI08_17640	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CTI08_17645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTI08_17660	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CTI08_17670	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CTI08_17670	COG0644	oxidoreductase
CTI08_17675	COG0425	Belongs to the sulfur carrier protein TusA family
CTI08_17680	COG4535	Mg2 and Co2 transporter CorC
CTI08_17690	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTI08_17710	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CTI08_17715	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CTI08_17715	COG0475	glutathione-regulated potassium exporter activity
CTI08_17720	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CTI08_17730	COG0484	heat shock protein binding
CTI08_17735	COG0789	Transcriptional regulator
CTI08_17740	COG0598	Magnesium transport protein CorA
CTI08_17760	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CTI08_17765	COG1074	ATP-dependent DNA helicase activity
CTI08_17770	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CTI08_17790	COG2226	methyltransferase
CTI08_17805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTI08_17810	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CTI08_17825	COG2111	Na H antiporter
CTI08_17825	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CTI08_17830	COG1006	Multisubunit Na H antiporter MnhC subunit
CTI08_17835	COG0651	ATP synthesis coupled electron transport
CTI08_17845	COG2212	antiporter activity
CTI08_17865	COG0195	Participates in both transcription termination and antitermination
CTI08_17915	COG0237	dephospho-CoA kinase activity
CTI08_17925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTI08_17940	COG0497	DNA recombination
CTI08_17950	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CTI08_17980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CTI08_17980	COG2169	Transcriptional regulator
CTI08_17985	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CTI08_18055	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CTI08_18070	COG0326	Molecular chaperone. Has ATPase activity
CTI08_18085	COG2056	Na+-H+ antiporter family
CTI08_18090	COG0596	Alpha beta hydrolase
CTI08_18185	COG0546	phosphoglycolate phosphatase activity
CTI08_18190	COG1716	ATPase activity
CTI08_18235	COG0181	hydroxymethylbilane synthase activity
CTI08_18245	COG3275	phosphorelay sensor kinase activity
CTI08_18265	COG1538	Outer membrane efflux protein
CTI08_18270	COG0697	spore germination
CTI08_18295	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CTI08_18300	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CTI08_18305	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CTI08_18310	COG0772	Belongs to the SEDS family
CTI08_18335	COG4974	Belongs to the 'phage' integrase family
CTI08_18340	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CTI08_18350	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CTI08_18360	COG2197	response regulator
CTI08_18375	COG0793	Belongs to the peptidase S41A family
CTI08_18380	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CTI08_18385	COG0795	lipopolysaccharide-transporting ATPase activity
CTI08_18425	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CTI08_18425	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CTI08_18435	COG0004	ammonium transporteR
CTI08_18440	COG0347	Belongs to the P(II) protein family
CTI08_18450	COG0606	chelatase, subunit chli
CTI08_18535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CTI08_18585	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CTI08_18615	COG0659	secondary active sulfate transmembrane transporter activity
CTI08_18620	COG0589	response to stress
CTI08_18650	COG0606	chelatase, subunit chli
CTI08_18655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTI08_18665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTI08_18680	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CTI08_18695	COG0318	PFAM AMP-dependent synthetase and ligase
CTI08_18705	COG0477	Major facilitator Superfamily
CTI08_18710	COG2860	membrane
CTI08_18720	COG1253	flavin adenine dinucleotide binding
CTI08_18730	COG2814	Major facilitator Superfamily
CTI08_18740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CTI08_18775	COG0655	NAD(P)H dehydrogenase (quinone) activity
CTI08_18785	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CTI08_18855	COG0758	DNA mediated transformation
CTI08_18865	COG0697	spore germination
CTI08_18870	COG1309	transcriptional regulator
CTI08_18885	COG0386	Belongs to the glutathione peroxidase family
CTI08_18950	COG1121	(ABC) transporter
CTI08_18955	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CTI08_18960	COG1280	lysine exporter protein (LysE YggA)
CTI08_18965	COG2837	iron assimilation
CTI08_18975	COG0281	malic enzyme
CTI08_19020	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CTI08_19020	COG0519	Catalyzes the synthesis of GMP from XMP
CTI08_19025	COG4399	Belongs to the UPF0754 family
CTI08_19030	COG2259	Doxx family
CTI08_19035	COG0586	Pfam SNARE associated Golgi protein
CTI08_19050	COG1192	Involved in chromosome partitioning
CTI08_19060	COG0271	Belongs to the BolA IbaG family
CTI08_19080	COG2267	carboxylic ester hydrolase activity
CTI08_19100	COG3321	synthase
CTI08_19100	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CTI08_19100	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CTI08_19100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CTI08_19105	COG1960	acyl-CoA dehydrogenase activity
CTI08_19115	COG2197	response regulator
CTI08_19125	COG3916	Acyl-homoserine-lactone synthase
CTI08_19130	COG0477	Major facilitator Superfamily
CTI08_19135	COG1024	Enoyl-CoA hydratase
CTI08_19140	COG1024	Enoyl-CoA hydratase
CTI08_19145	COG1960	acyl-CoA dehydrogenase activity
CTI08_19150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTI08_19170	COG1113	amino acid transport
CTI08_19175	COG1113	amino acid transport
CTI08_19180	COG0251	oxidation-reduction process
CTI08_19195	COG1522	sequence-specific DNA binding
CTI08_19220	COG0564	pseudouridine synthase activity
CTI08_19250	COG1051	belongs to the nudix hydrolase family
CTI08_19270	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CTI08_19285	COG1802	Transcriptional regulator
CTI08_19295	COG1448	Aminotransferase
CTI08_19300	COG0277	FAD linked oxidase domain protein
CTI08_19310	COG2186	Transcriptional regulator
CTI08_19320	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CTI08_19325	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CTI08_19340	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CTI08_19345	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CTI08_19370	COG0438	transferase activity, transferring glycosyl groups
CTI08_19405	COG1596	polysaccharide export
CTI08_19430	COG0728	peptidoglycan biosynthetic process
CTI08_19435	COG3023	N-Acetylmuramoyl-L-alanine amidase
CTI08_19495	COG0546	phosphoglycolate phosphatase activity
CTI08_19500	COG1028	Short-chain dehydrogenase reductase Sdr
CTI08_19520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTI08_19525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTI08_19530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTI08_19535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTI08_19540	COG1116	anion transmembrane transporter activity
CTI08_19545	COG1309	transcriptional regulator
CTI08_19550	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CTI08_19560	COG0196	riboflavin kinase activity
CTI08_19565	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CTI08_19575	COG1047	Peptidyl-prolyl cis-trans
CTI08_19615	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CTI08_19675	COG2951	lytic endotransglycosylase activity
CTI08_19680	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CTI08_19700	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CTI08_19710	COG0671	phosphoesterase, PA-phosphatase related
CTI08_19715	COG0861	Integral membrane protein TerC family
CTI08_19730	COG0754	glutathionylspermidine amidase activity
CTI08_19740	COG0402	S-adenosylhomocysteine deaminase activity
CTI08_19755	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CTI08_19760	COG1230	cation diffusion facilitator family transporter
CTI08_19775	COG0706	membrane insertase activity
CTI08_19790	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CTI08_19860	COG2832	Protein of unknown function (DUF454)
CTI08_19925	COG1525	nuclease
CTI08_20000	COG1475	DNA binding
CTI08_20020	COG3853	Toxic anion resistance protein (TelA)
CTI08_20150	COG0484	heat shock protein binding
CTI08_20205	COG2826	transposase and inactivated derivatives, IS30 family
CTI08_20220	COG2826	transposase and inactivated derivatives, IS30 family
CTI08_20230	COG2826	transposase and inactivated derivatives, IS30 family
CTI08_20260	COG0741	lytic transglycosylase activity
CTI08_20295	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CTI08_20375	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII