locus-tag class description AB987_0002 ENOG4105R8C Transcriptional regulator AB987_0003 ENOG4105C1G acyl-Coa dehydrogenase AB987_0004 ENOG4107QX3 carboxylase AB987_0005 ENOG4105E39 Enoyl-CoA hydratase AB987_0008 ENOG4105CC0 LysR family Transcriptional regulator AB987_0011 ENOG4108NIW Leucine export protein LeuE AB987_0013 ENOG4108KAZ Involved in phosphonate degradation (By similarity) AB987_0014 ENOG4107STF Involved in phosphonate degradation (By similarity) AB987_0016 ENOG4107RCV ABC transporter, permease AB987_0017 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) AB987_0018 ENOG4105C4Y ABC transporter AB987_0021 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase AB987_0022 ENOG4107HP6 Transcriptional regulator AB987_0024 ENOG4105HEI LysR family (Transcriptional regulator AB987_0026 ENOG4105F9F transposase AB987_0027 ENOG4105C2C drug resistance transporter, Bcr CflA AB987_0030 ENOG4105FUY alpha subunit AB987_0032 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) AB987_0033 ENOG4105CPW cytochrome b561 AB987_0034 ENOG4107VGR Catalase AB987_0037 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein AB987_0038 ENOG4105DZS Phenylacetate-CoA ligase AB987_0039 ENOG4105CHU acetyl-coa acetyltransferase AB987_0040 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase AB987_0041 ENOG4108UKI Enoyl-CoA hydratase AB987_0042 ENOG4105E39 Enoyl-CoA hydratase AB987_0043 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) AB987_0044 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit AB987_0045 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit AB987_0046 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit AB987_0047 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit AB987_0048 ENOG4105DXM phenylacetic acid degradation protein AB987_0049 ENOG4105EJQ L-serine dehydratase AB987_0050 ENOG4107QTZ amino acid AB987_0051 ENOG4105CZJ Aldehyde dehydrogenase AB987_0054 ENOG4105D5G Transposase AB987_0062 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) AB987_0064 ENOG4108Z4X TRANSCRIPTIONal AB987_0069 ENOG4108HW3 (ABC) transporter AB987_0071 ENOG4105MRR Transcriptional regulator (By similarity) AB987_0074 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF AB987_0075 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase AB987_0079 ENOG4105E2A Dehydrogenase AB987_0082 ENOG4105R8C Transcriptional regulator AB987_0084 ENOG4105DQ6 Transposase AB987_0089 ENOG4105F9F transposase AB987_0098 ENOG4107R4J Chloride channel AB987_0099 ENOG4108JIK carboxylase AB987_0103 ENOG4105C5A transporter AB987_0104 ENOG4108WAV Transcriptional regulator AB987_0118 ENOG4105D1S lipid A biosynthesis AB987_0119 ENOG4105BZU Histidine kinase AB987_0125 ENOG4108Z4U Ferredoxin AB987_0133 ENOG4105DFG type I secretion outer membrane protein AB987_0134 ENOG4108IUZ ABC transporter AB987_0135 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA AB987_0137 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase AB987_0138 ENOG4105C2X Arabinose 5-phosphate isomerase AB987_0196 ENOG4105II7 pyrroline-5-carboxylate reductase AB987_0199 ENOG4105F9F transposase AB987_0200 ENOG4105F9F transposase AB987_0202 ENOG4105VEQ Cold shock protein AB987_0203 ENOG410829K Lysine exporter protein (Lyse ygga) AB987_0210 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) AB987_0223 ENOG4105EUV Phenol 2-monooxygenase AB987_0227 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein AB987_0229 ENOG4108KB2 LysR family Transcriptional regulator AB987_0231 ENOG4105FUY alpha subunit AB987_0232 ENOG4108UKV benzoate 1,2-dioxygenase AB987_0233 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein AB987_0234 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase AB987_0235 ENOG4105DKK Benzoate AB987_0236 ENOG4105D2S major facilitator superfamily AB987_0237 ENOG4105D5G Transposase AB987_0238 ENOG4105D2S major facilitator superfamily AB987_0241 ENOG4105CQ7 ATP-dependent helicase AB987_0242 ENOG4105D3R alkyl hydroperoxide reductase AB987_0244 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) AB987_0246 ENOG4108JU3 Alkyl hydroperoxide reductase AB987_0248 ENOG4108K3A Glutathione S-transferase AB987_0250 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) AB987_0251 ENOG4108TGY Glutathione S-transferase AB987_0253 ENOG4108ZG0 Ompa motb domain protein AB987_0254 ENOG4105CD3 dihydroorotase AB987_0260 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AB987_0263 ENOG4108UKZ OsmC family AB987_0264 ENOG4107RYR Transcriptional regulator, Crp Fnr family AB987_0265 ENOG4105CPC Aldo Keto reductase AB987_0268 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis AB987_0270 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase AB987_0272 ENOG4105DFP Integrase AB987_0274 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) AB987_0280 ENOG4108R1E Serine threonine protein phosphatase 1 AB987_0299 ENOG4107ZQ5 Phage-associated protein, HI1409 family AB987_0305 ENOG4105F9F transposase AB987_0330 ENOG4105CFH Aspartokinase AB987_0332 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) AB987_0334 ENOG4105CPW cytochrome b561 AB987_0335 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) AB987_0336 ENOG4105C7N Xanthine uracil vitamin C permease AB987_0338 ENOG4105F95 Monooxygenase AB987_0345 ENOG4105F95 Monooxygenase AB987_0346 ENOG4105JQZ Methyltransferase AB987_0347 ENOG4105EJC lysr family transcriptional regulator AB987_0349 ENOG4106DSS Tartrate dehydratase subunit alpha AB987_0350 ENOG4107GFK fumarate AB987_0352 ENOG4107RN6 Monooxygenase AB987_0358 ENOG4105EPF Outer membrane porin AB987_0359 ENOG4105D2S major facilitator superfamily AB987_0360 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) AB987_0361 ENOG4105E6M Sulphatase-modifying factor protein AB987_0364 ENOG4105E3J oxidoreductase AB987_0367 ENOG4108SC4 )-transporter AB987_0368 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase AB987_0371 ENOG4105C1G acyl-Coa dehydrogenase AB987_0372 ENOG4105EPF Outer membrane porin AB987_0373 ENOG4105NI3 Protein of unknown function (DUF3237) AB987_0376 ENOG4105JXH GntR family transcriptional regulator AB987_0377 ENOG4105CZJ Aldehyde dehydrogenase AB987_0379 ENOG4105EQX glucarate dehydratase AB987_0380 ENOG4105DJB Major Facilitator Superfamily AB987_0381 ENOG4105CTX dehydratase AB987_0382 ENOG4105DJP Membrane AB987_0383 ENOG4108ZX5 transcriptional regulator AB987_0384 ENOG4107RGH Aldehyde dehydrogenase AB987_0386 ENOG4105F9F transposase AB987_0387 ENOG4105C85 amino acid AB987_0391 ENOG4105C26 Dehydrogenase AB987_0395 ENOG4105CUB amino acid AB987_0397 ENOG4105C85 amino acid AB987_0400 ENOG4105D01 (LipO)protein AB987_0401 ENOG4105F9F transposase AB987_0406 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase AB987_0410 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) AB987_0414 ENOG4108JQ5 ABC transporter AB987_0415 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component AB987_0416 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component AB987_0418 ENOG4105E9H Lytic Murein transglycosylase AB987_0418 ENOG4105E9H Lytic Murein transglycosylase AB987_0419 ENOG4107RZZ dna polymerase iii epsilon subunit AB987_0421 ENOG4105E09 nadh pyrophosphatase AB987_0423 ENOG4105W4M Transport-associated protein AB987_0426 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) AB987_0428 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) AB987_0429 ENOG4108ZUB Lysine exporter protein (Lyse ygga) AB987_0434 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family AB987_0435 ENOG4105D0A hydroxylase AB987_0436 ENOG4107RAQ aminopeptidase AB987_0443 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase AB987_0448 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b AB987_0450 ENOG4105D82 Glutamate dehydrogenase AB987_0451 ENOG4108R3D Electron transport complex AB987_0452 ENOG4105CSM endonuclease III AB987_0458 ENOG4105CJN penicillin-binding protein AB987_0459 ENOG4106H78 methyltransferase AB987_0462 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) AB987_0464 ENOG4105CQM Urea amidohydrolase subunit alpha AB987_0471 ENOG4107RET Isocitrate lyase AB987_0473 ENOG4105C37 (CBS) domain AB987_0475 ENOG4105D4T Citrate transporter AB987_0478 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) AB987_0480 ENOG4108MRJ AB987_0484 ENOG4105VCQ rubredoxin AB987_0485 ENOG4107QZF nitrite reductase NADPH large subunit AB987_0487 ENOG4105C5Q Transcriptional regulator AB987_0491 ENOG4107U91 Rhomboid family AB987_0492 ENOG4105CV6 ABC transporter, permease AB987_0493 ENOG4108I0Y (ABC) transporter AB987_0494 ENOG4108UJV acyl-CoA thioesterase i AB987_0498 ENOG4107RNH Outer membrane receptor FepA AB987_0502 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) AB987_0503 ENOG4105E6M Sulphatase-modifying factor protein AB987_0511 ENOG4105CJ3 phosphate transporter AB987_0513 ENOG4105C3R Methionine synthase AB987_0520 ENOG4105CSP Major Facilitator Superfamily AB987_0522 ENOG4108PZW LysR family Transcriptional regulator AB987_0524 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) AB987_0525 ENOG4105EU0 Major facilitator Superfamily AB987_0526 ENOG4108R6W Transcriptional regulator, ARAC family AB987_0527 ENOG4105CSV Glutaminase AB987_0528 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) AB987_0530 ENOG4105CSH Transporter AB987_0532 ENOG4105C7K acetolactate synthase AB987_0533 ENOG41069M3 Transcriptional regulator AB987_0536 ENOG4106YT9 Enoyl-CoA hydratase AB987_0538 ENOG4105CND Glycosyl transferase, family 2 AB987_0539 ENOG4107BJW polysaccharide deacetylase AB987_0541 ENOG4108VWS Yaeq family AB987_0542 ENOG4105D5G Transposase AB987_0544 ENOG4105CK2 sodium dicarboxylate symporter AB987_0545 ENOG4105CKI cobalamin synthesis protein AB987_0549 ENOG4105C94 Transporter AB987_0550 ENOG4105C94 Transporter AB987_0551 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) AB987_0556 ENOG4107QK5 Homocysteine s-methyltransferase AB987_0557 ENOG4105D5Q Arginine ornithine antiporter AB987_0564 ENOG4105M6W Crispr-associated protein, Csy3 family AB987_0576 ENOG4105F9F transposase AB987_0579 ENOG4108UUM single-stranded DNA-binding protein AB987_0584 ENOG4105WXW Antirepressor AB987_0588 ENOG4105DFP Integrase AB987_0589 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) AB987_0590 ENOG4105C0R drug resistance transporter emrb qaca subfamily AB987_0591 ENOG4105CW7 secretion protein, HlyD family AB987_0592 ENOG4108VUY thioesterase Superfamily protein AB987_0593 ENOG4105D52 delta-aminolevulinic acid dehydratase AB987_0594 ENOG4105MWK D-amino acid dehydrogenase, small subunit AB987_0595 ENOG4105ECP epimerase AB987_0599 ENOG4107RH8 nuclease SbcCD subunit D AB987_0600 ENOG4105EYH Exonuclease AB987_0601 ENOG4105DFA alanine racemase domain protein AB987_0602 ENOG4105CZX twitching motility protein AB987_0603 ENOG4105CZX twitching motility protein AB987_0604 ENOG41090R7 Ferric uptake AB987_0609 ENOG4105E7A Glutamine amidotransferase AB987_0612 ENOG4107QKV phosphomannomutase AB987_0614 ENOG4105C4R Atp-dependent dna helicase AB987_0615 ENOG4108ZG0 Ompa motb domain protein AB987_0616 ENOG4106HNH Acyl-transferase AB987_0619 ENOG4107QMS site-determining protein AB987_0623 ENOG4105CNU cell division protein FtsK AB987_0624 ENOG4105C3M thioredoxin reductase AB987_0625 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) AB987_0627 ENOG4105KEG ribosomal-protein-alanine acetyltransferase AB987_0637 ENOG4108YXA Membrane AB987_0638 ENOG4105EUB pirin domain protein AB987_0640 ENOG4105C4K Nad synthetase AB987_0643 ENOG4105E3J oxidoreductase AB987_0644 ENOG4105C26 Dehydrogenase AB987_0645 ENOG4105DVW rieske (2Fe-2S) AB987_0647 ENOG4105C94 Transporter AB987_0648 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) AB987_0649 ENOG4105EJC lysr family transcriptional regulator AB987_0652 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding AB987_0656 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase AB987_0657 ENOG4105C34 Pseudouridine synthase AB987_0658 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane AB987_0659 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) AB987_0662 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) AB987_0668 ENOG4105C5T Phosphoribosyl pyrophosphate synthase AB987_0674 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) AB987_0676 ENOG4105DWF phosphomethylpyrimidine kinase AB987_0677 ENOG4109066 lysm domain bon superfamily protein AB987_0679 ENOG4105CHR reductase AB987_0680 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase AB987_0682 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein AB987_0683 ENOG4108BPE -transporting atpase AB987_0684 ENOG4107RTD sua5 ycio yrdc ywlc family protein AB987_0685 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) AB987_0686 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) AB987_0687 ENOG4105FE9 pseudouridine synthase AB987_0689 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) AB987_0690 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) AB987_0692 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) AB987_0693 ENOG4108K4C ec 3.1.3.12 AB987_0694 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase AB987_0695 ENOG4106UW1 Major Facilitator superfamily AB987_0699 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) AB987_0701 ENOG4105HF0 Membrane AB987_0704 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY AB987_0706 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) AB987_0717 ENOG4105D1F ATP-binding protein AB987_0719 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) AB987_0725 ENOG4105K6H D-cysteine desulfhydrase AB987_0726 ENOG4105CBX hi0933 family AB987_0731 ENOG4105DP0 ferredoxin-NADP reductase AB987_0732 ENOG4105DUM transcriptional regulator, lysR family AB987_0737 ENOG4105C8S subunit m AB987_0738 ENOG4105D65 subunit l AB987_0740 ENOG4107UFS subunit j AB987_0743 ENOG4108IEH NADH dehydrogenase subunit g AB987_0744 ENOG4107QIZ NADH dehydrogenase AB987_0745 ENOG4105GKE subunit e AB987_0749 ENOG4105BZU Histidine kinase AB987_0751 ENOG4105E0F Histidine kinase AB987_0752 ENOG4107EXC regulatoR AB987_0753 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) AB987_0755 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) AB987_0757 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) AB987_0758 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) AB987_0760 ENOG4105ETT transcriptional Regulator, LysR family AB987_0762 ENOG4106P55 Transcriptional regulator AB987_0765 ENOG4106P55 Transcriptional regulator AB987_0767 ENOG4107EFR Flavocytochrome c AB987_0768 ENOG41079YP Citrate utilization protein b AB987_0775 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) AB987_0776 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) AB987_0777 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) AB987_0780 ENOG4105VR0 copper resistance AB987_0781 ENOG4105E3B Multicopper oxidase AB987_0783 ENOG4108HCJ Hydrolase AB987_0784 ENOG4105DJV ribulose-phosphate 3-epimerase AB987_0789 ENOG41072GX Peptidase M22 Glycoprotease AB987_0790 ENOG4108Z0R Transferase AB987_0796 ENOG4105CRQ synthase (Component I) AB987_0798 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) AB987_0799 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) AB987_0800 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) AB987_0816 ENOG4105K56 Transcriptional regulator AB987_0817 ENOG4108ZHJ Organic hydroperoxide resistance protein AB987_0818 ENOG4107QHF type ii secretion system protein e AB987_0822 ENOG4105C2M dna polymerase I AB987_0823 ENOG4108VIA integral membrane protein AB987_0824 ENOG4105II7 pyrroline-5-carboxylate reductase AB987_0825 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) AB987_0827 ENOG4105C9X ppx gppa phosphatase AB987_0829 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) AB987_0832 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) AB987_0837 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) AB987_0840 ENOG4105W39 Membrane AB987_0841 ENOG4105CYM Glutathione S-transferase AB987_0844 ENOG4105CEY Amp-dependent synthetase and ligase AB987_0845 ENOG4105N42 UPF0307 protein AB987_0846 ENOG41080Z8 PHOSPHOCARRIER protein AB987_0850 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase AB987_0851 ENOG4105DJ0 Poly(A) Polymerase AB987_0852 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein AB987_0853 ENOG4105DXN mazG family AB987_0855 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) AB987_0858 ENOG4105C6T cysteine synthase AB987_0859 ENOG4105BZU Histidine kinase AB987_0860 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase AB987_0861 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase AB987_0862 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) AB987_0866 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) AB987_0867 ENOG4105W8H transhydrogenase (subunit alpha AB987_0868 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) AB987_0869 ENOG4106UX7 integral membrane protein AB987_0876 ENOG4105H3G oxidoreductase AB987_0877 ENOG4105C3M thioredoxin reductase AB987_0878 ENOG4105CAU Arsenical resistance protein, ArsH AB987_0879 ENOG4105D6J arsenicaL-resistance protein AB987_0881 ENOG4105KBH arsR family transcriptional regulator AB987_0885 ENOG4105CE1 Ferrous iron transport protein b AB987_0887 ENOG4108IJF Heavy metal efflux pump, CzcA AB987_0892 ENOG4105E3B Multicopper oxidase AB987_0895 ENOG4105GR3 Histidine kinase AB987_0907 ENOG4105DQ6 Transposase AB987_0913 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) AB987_0915 ENOG4107RSM transcriptional regulator AB987_0917 ENOG4105CUZ uba thif-type nad fad binding protein AB987_0918 ENOG4107QM5 aconitate hydratase AB987_0919 ENOG4105F8V Hydrolase, tatD family AB987_0922 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) AB987_0924 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 AB987_0927 ENOG4107R3N Filamentation induced by cAMP protein fic AB987_0935 ENOG4105UYK outer membrane protein a AB987_0943 ENOG4105MP0 transposase AB987_0946 ENOG4105BZU Histidine kinase AB987_0948 ENOG4108ZP8 Acetolactate synthase small subunit AB987_0949 ENOG4105C7K acetolactate synthase AB987_0954 ENOG4105DJY efflux transporter, rnd family, mfp subunit AB987_0955 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) AB987_0956 ENOG4105ENJ RND efflux system, outer membrane lipoprotein AB987_0957 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH AB987_0959 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) AB987_0960 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) AB987_0962 ENOG4105VW4 glutaredoxin 3 AB987_0966 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) AB987_0970 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) AB987_0974 ENOG4105WVQ Fe-S assembly protein IscX AB987_0977 ENOG4105CN1 protease AB987_0983 ENOG4105C26 Dehydrogenase AB987_0984 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family AB987_0985 ENOG4105C6Z Gluconate AB987_0986 ENOG4108UHU Aldolase AB987_0987 ENOG4105C01 Dihydroxy-acid dehydratase AB987_0988 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) AB987_0989 ENOG4108DNC Involved in acetate metabolism (By similarity) AB987_0990 ENOG4107GFK fumarate AB987_0994 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) AB987_0996 ENOG4108ESX Receptor AB987_0998 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) AB987_1000 ENOG4105DWV Homoserine O-trans-acetylase AB987_1020 ENOG4105CIY formyltetrahydrofolate deformylase AB987_1022 ENOG4107RGH Aldehyde dehydrogenase AB987_1023 ENOG4105KDC 50s ribosomal protein l28 AB987_1024 ENOG4105W0E 50S ribosomal protein L33 AB987_1025 ENOG4105CKD glutathione-regulated potassium-efflux system protein AB987_1029 ENOG4105VFU Rna-binding protein AB987_1030 ENOG4105C4R Atp-dependent dna helicase AB987_1033 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) AB987_1035 ENOG4105KVH Transcriptional regulator AB987_1037 ENOG41069P5 Protein slyX homolog AB987_1038 ENOG4105C5H ABC transporter AB987_1040 ENOG4105N14 lysine exporter protein LysE YggA AB987_1041 ENOG4105D1S lipid A biosynthesis AB987_1043 ENOG4105CK2 sodium dicarboxylate symporter AB987_1054 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) AB987_1062 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase AB987_1067 ENOG4108W5M transcriptional regulator AB987_1070 ENOG4105D29 Helix-turn-helix type 11 domain protein AB987_1071 ENOG4107XGZ Hydrolase AB987_1072 ENOG4105EI2 Pseudouridine synthase AB987_1074 ENOG4105C03 ribonuclease AB987_1078 ENOG4105CBN LysR family transcriptional regulator AB987_1079 ENOG4105EMU Dehydrogenase AB987_1080 ENOG4105CSA Coproporphyrinogen iii oxidase AB987_1082 ENOG4107QI1 Mate efflux family protein AB987_1084 ENOG4107T8P acyl-Coa dehydrogenase AB987_1103 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) AB987_1104 ENOG4105C5X domain protein AB987_1107 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) AB987_1109 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase AB987_1111 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) AB987_1112 ENOG4108JU5 Magnesium and cobalt efflux protein AB987_1113 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) AB987_1114 ENOG4108Z7R Chaperone CsaA AB987_1116 ENOG4108VAU general secretion pathway protein G AB987_1117 ENOG4105D7Q type ii secretion system AB987_1118 ENOG4105C25 Primosomal protein n' AB987_1119 ENOG4105CKD glutathione-regulated potassium-efflux system protein AB987_1122 ENOG4105DVC DnaJ domain protein AB987_1123 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) AB987_1124 ENOG4107QUT magnesium and cobalt transport protein CorA AB987_1128 ENOG4107QYX exodeoxyribonuclease v alpha AB987_1129 ENOG4107QKA exodeoxyribonuclease V beta AB987_1130 ENOG4105DSY exodeoxyribonuclease V, gamma AB987_1132 ENOG4105CSR polyphosphate kinase 2 AB987_1134 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) AB987_1138 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase AB987_1142 ENOG4105D65 subunit l AB987_1143 ENOG4108ZE9 Monovalent cation H antiporter subunit C AB987_1144 ENOG4107R4Z monovalent cation h antiporter subunit d AB987_1145 ENOG4105SC1 monovalent cation H antiporter subunit E AB987_1146 ENOG4105W4C monovalent cation H antiporter subunit F AB987_1147 ENOG4105KJM monovalent cation h antiporter subunit g AB987_1150 ENOG4105CHV Transcription elongation factor NusA AB987_1155 ENOG4107EJC Preprotein translocase subunit SecG AB987_1157 ENOG4107QHF type ii secretion system protein e AB987_1160 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) AB987_1162 ENOG4105C2N RNA methyltransferase TrmH family group 3 AB987_1165 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) AB987_1167 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) AB987_1173 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) AB987_1174 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase AB987_1189 ENOG4107ZXU DSBA oxidoreductase AB987_1192 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) AB987_1196 ENOG4105D3Y Na H antiporter AB987_1198 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) AB987_1209 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) AB987_1210 ENOG4105PM1 preprotein translocase subunit SecE AB987_1218 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) AB987_1219 ENOG4105TV9 FHA Domain-Containing protein AB987_1220 ENOG4105GVR general secretion pathway protein D AB987_1223 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS AB987_1229 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) AB987_1230 ENOG4108NEV two component transcriptional regulator, LytTR family AB987_1231 ENOG4108HRK Histidine kinase AB987_1234 ENOG4108UTW Plays a role in the regulation of phosphate uptake AB987_1235 ENOG4105DFG type I secretion outer membrane protein AB987_1236 ENOG4108RNG Permease of the drug metabolite transporter AB987_1241 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) AB987_1242 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters AB987_1243 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) AB987_1244 ENOG4105CNI cell division protein FtsW AB987_1247 ENOG4105CE1 Ferrous iron transport protein b AB987_1249 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) AB987_1250 ENOG4105T95 Thiol disulfide interChange protein AB987_1251 ENOG4105D6E homoserine dehydrogenase AB987_1253 ENOG41061WM D-Alanyl-D-Alanine AB987_1255 ENOG4107TUY Histidine kinase AB987_1256 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family AB987_1257 ENOG4105CN1 protease AB987_1258 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) AB987_1259 ENOG4108K5H permease YjgP YjgQ family protein AB987_1267 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) AB987_1269 ENOG4105BZU Histidine kinase AB987_1272 ENOG4105C0P Mg chelatase subunit ChlI AB987_1273 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family AB987_1275 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) AB987_1278 ENOG4105EPF Outer membrane porin AB987_1279 ENOG4105F0N pyrophosphate phospho-hydrolase AB987_1282 ENOG4105CEY Amp-dependent synthetase and ligase AB987_1283 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AB987_1284 ENOG41079KZ Major Facilitator Superfamily AB987_1285 ENOG4105EN6 Membrane AB987_1287 ENOG4105EE5 Membrane protein terC AB987_1289 ENOG4108URH decarboxylase AB987_1290 ENOG4105C0R drug resistance transporter emrb qaca subfamily AB987_1292 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) AB987_1293 ENOG4105E3W Two component transcriptional regulator (Winged helix family AB987_1294 ENOG4105EB3 Histidine kinase AB987_1295 ENOG4105CT7 inner membrane cred family protein AB987_1299 ENOG4105CCT upf0313 protein AB987_1303 ENOG4105CS1 NAD(P)H quinone oxidoreductase AB987_1305 ENOG4105C6T cysteine synthase AB987_1322 ENOG4105C79 DNA protecting protein DprA AB987_1325 ENOG4108IND Tetr family transcriptional regulator AB987_1326 ENOG4107RTG Major Facilitator superfamily AB987_1328 ENOG4108V06 Glutathione peroxidase AB987_1336 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) AB987_1341 ENOG4105FDK ABC transporter AB987_1342 ENOG4105FAV ABC, transporter AB987_1344 ENOG4105EZR dyp-type peroxidase family protein AB987_1345 ENOG4107R1I NAD-dependent malic enzyme AB987_1350 ENOG4105EUB pirin domain protein AB987_1354 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) AB987_1355 ENOG4106MP8 UPF0754 membrane protein AB987_1356 ENOG4108VBZ doxx family AB987_1357 ENOG4105DQR SNARE associated Golgi AB987_1363 ENOG4107QJE Chromosome Partitioning Protein AB987_1365 ENOG4107PSF BolA-like protein AB987_1369 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) AB987_1371 ENOG4105CSH Transporter AB987_1372 ENOG4105E39 Enoyl-CoA hydratase AB987_1373 ENOG4105E39 Enoyl-CoA hydratase AB987_1374 ENOG4105C1G acyl-Coa dehydrogenase AB987_1376 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase AB987_1377 ENOG4105C26 Dehydrogenase AB987_1379 ENOG4105C85 amino acid AB987_1380 ENOG4105M4H endoribonuclease L-psp AB987_1383 ENOG4105EW9 transcriptional regulator AsnC family AB987_1388 ENOG4105D3G Pseudouridine synthase AB987_1395 ENOG4108I0Z Aconitate hydratase AB987_1396 ENOG4105BZN citrate synthase AB987_1397 ENOG4105CR4 methylisocitrate lyase AB987_1398 ENOG4105DRR Transcriptional regulator, GntR family AB987_1399 ENOG4105CGF Aromatic amino acid aminotransferase AB987_1400 ENOG4105CXG d-lactate dehydrogenase AB987_1402 ENOG41073TP transcriptional regulator AB987_1403 ENOG4105DAA L-lactate AB987_1404 ENOG4107QKV phosphomannomutase AB987_1406 ENOG4105CMR udp-glucose 4-epimerase AB987_1408 ENOG4105C6Y Udp-glucose 6-dehydrogenase AB987_1409 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase AB987_1410 ENOG4108MRJ AB987_1411 ENOG4105D3Q Sugar transferase AB987_1415 ENOG4105H63 Glycosyl transferase, family 2 AB987_1416 ENOG4105ER6 polysaccharide biosynthesis protein AB987_1418 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase AB987_1419 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) AB987_1420 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase AB987_1421 ENOG4105C1B dTDP-glucose 4-6-dehydratase AB987_1422 ENOG4107QQG Dehydrogenase AB987_1423 ENOG4105DAY polysaccharide export protein AB987_1425 ENOG4105D75 Capsular exopolysaccharide family AB987_1426 ENOG4108V1T peptidylprolyl cis-trans isomerase AB987_1427 ENOG4108V1T peptidylprolyl cis-trans isomerase AB987_1428 ENOG4105CJR Integral membrane protein (MviN AB987_1429 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase AB987_1430 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase AB987_1432 ENOG4105HSS phospholipase C AB987_1438 ENOG41062JF Transcriptional regulator AB987_1441 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) AB987_1442 ENOG4105UBK short-chain dehydrogenase reductase AB987_1445 ENOG4107QZM n-acetylglutamate synthase AB987_1446 ENOG4105GVF (ABC) transporter AB987_1447 ENOG4105GVF (ABC) transporter AB987_1448 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) AB987_1449 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component AB987_1450 ENOG4108VM9 ABC, transporter AB987_1451 ENOG4108R86 Transcriptional regulator AB987_1452 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) AB987_1454 ENOG4105DTN riboflavin biosynthesis protein ribF AB987_1455 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) AB987_1457 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase AB987_1467 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) AB987_1468 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) AB987_1469 ENOG4105D74 hydrolase AB987_1471 ENOG4108821 RND type efflux pump AB987_1472 ENOG4108821 RND type efflux pump AB987_1473 ENOG4108821 RND type efflux pump AB987_1474 ENOG4105C5H ABC transporter AB987_1475 ENOG4105DQR SNARE associated Golgi AB987_1477 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AB987_1479 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) AB987_1481 ENOG4105VG0 50S ribosomal protein l34 AB987_1484 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins AB987_1487 ENOG4105PGM cation diffusion facilitator family transporter AB987_1488 ENOG4105T95 Thiol disulfide interChange protein AB987_1490 ENOG4108UGV hypoxanthine phosphoribosyltransferase AB987_1492 ENOG4107QUY Guanine deaminase AB987_1494 ENOG4106032 Glutathionylspermidine synthase AB987_1496 ENOG4105DU1 integral membrane protein, terc AB987_1497 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase AB987_1500 ENOG4105DFU Cell wall formation (By similarity) AB987_1503 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) AB987_1504 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit AB987_1505 ENOG4105CVE Lytic murein transglycosylase AB987_1517 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) AB987_1528 ENOG4105C8J )-transporter AB987_1530 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B AB987_1535 ENOG4108W5M transcriptional regulator AB987_1536 ENOG4105C2W permease AB987_1538 ENOG4108IG5 Transcriptional regulator AB987_1539 ENOG4105DJY efflux transporter, rnd family, mfp subunit AB987_1546 ENOG4105F27 Major Facilitator AB987_1547 ENOG4105CV8 reductase AB987_1548 ENOG4105CV8 reductase AB987_1549 ENOG4105HEI LysR family (Transcriptional regulator AB987_1552 ENOG4105DQ4 alcohol dehydrogenase AB987_1553 ENOG4108R3E Dna-3-methyladenine glycosylase i AB987_1556 ENOG4105CEN a g-specific adenine glycosylase AB987_1560 ENOG4108ZZ3 UPF0260 protein AB987_1562 ENOG4105D1H recombination factor protein RarA AB987_1563 ENOG4105S64 Formate nitrite transporter AB987_1567 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) AB987_1568 ENOG4108RWI nicotinamidase AB987_1569 ENOG4105C09 Bile acid AB987_1572 ENOG4105EWC Purine nucleoside phosphorylase AB987_1576 ENOG4108RXX maleylacetoacetate isomerase AB987_1578 ENOG4105C85 amino acid AB987_1580 ENOG4105CKI cobalamin synthesis protein AB987_1584 ENOG4105CZE histidine utilization repressor AB987_1585 ENOG41090B9 response to stress AB987_1588 ENOG4105C85 amino acid AB987_1590 ENOG41088SP formiminoglutamate hydrolase AB987_1595 ENOG4105F9F transposase AB987_1596 ENOG41088SP formiminoglutamate hydrolase AB987_1598 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 AB987_1599 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) AB987_1600 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) AB987_1602 ENOG4108ZAI phosphatidylglycerophosphatase a AB987_1604 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) AB987_1607 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) AB987_1609 ENOG4105EAC phosphoserine phosphatase AB987_1614 ENOG4105KHC sulfurtransferase AB987_1617 ENOG4105BZU Histidine kinase AB987_1618 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AB987_1621 ENOG4107QJQ Mate efflux family protein AB987_1622 ENOG4105CHM Aminotransferase AB987_1623 ENOG4106BRA Membrane AB987_1626 ENOG4105D9M gamma-glutamylcysteine synthetase AB987_1631 ENOG4105IPS esterase AB987_1632 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AB987_1633 ENOG4108Z2U ureidoglycolate hydrolase AB987_1635 ENOG41061H0 Monooxygenase AB987_1638 ENOG41084YZ Hydrolase AB987_1644 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) AB987_1645 ENOG4105BZU Histidine kinase AB987_1648 ENOG4105KUZ arsenate reductase AB987_1649 ENOG4105CGK Exodeoxyribonuclease III AB987_1654 ENOG4105D7Z glutathione synthase AB987_1658 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) AB987_1659 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) AB987_1660 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) AB987_1663 ENOG41063SB peptidase AB987_1664 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) AB987_1665 ENOG4107QSN dihydrolipoamide acetyltransferase AB987_1668 ENOG4105E0K tonB-dependent siderophore receptor AB987_1671 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) AB987_1674 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) AB987_1676 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) AB987_1678 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase AB987_1679 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase AB987_1681 ENOG4105D64 Mechanosensitive ion channel AB987_1684 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) AB987_1685 ENOG4108W2Y isochorismatase AB987_1688 ENOG4105FBW Monooxygenase AB987_1689 ENOG4108UZX fmn reductase AB987_1692 ENOG4105BZU Histidine kinase AB987_1693 ENOG41062QD Membrane AB987_1694 ENOG4107QN1 sodium solute AB987_1696 ENOG4105C94 Transporter AB987_1698 ENOG4105BZU Histidine kinase AB987_1699 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) AB987_1700 ENOG4108WUH Transcriptional regulator, TetR family AB987_1701 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein AB987_1703 ENOG4105RA2 Membrane AB987_1704 ENOG4105DWF phosphomethylpyrimidine kinase AB987_1706 ENOG4107RDB Major Facilitator AB987_1707 ENOG4108UUM single-stranded DNA-binding protein AB987_1709 ENOG4108UMN azlc family AB987_1711 ENOG4105C85 amino acid AB987_1713 ENOG4108JPW Aminotransferase AB987_1714 ENOG4105C26 Dehydrogenase AB987_1716 ENOG4105CHJ isochorismatase hydrolase AB987_1717 ENOG4105EUB pirin domain protein AB987_1722 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) AB987_1755 ENOG4105C0D helicase AB987_1774 ENOG4105CUV Homoserine Kinase AB987_1777 ENOG41061CK Antibiotic biosynthesis monooxygenase AB987_1785 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) AB987_1791 ENOG4105CYC Transferase AB987_1792 ENOG4105E0F Histidine kinase AB987_1793 ENOG4105DPZ Two component transcriptional regulator (Winged helix family AB987_1795 ENOG4105CHH sulfate transporter AB987_1796 ENOG4105PDP Short chain dehydrogenase AB987_1798 ENOG4105C5H ABC transporter AB987_1814 ENOG4108IQI permease AB987_1819 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein AB987_1822 ENOG4105CJN penicillin-binding protein AB987_1823 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) AB987_1824 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) AB987_1827 ENOG4105DHI Methyltransferase AB987_1828 ENOG4108JQC penicillin-binding protein 1A AB987_1833 ENOG4105E4G Type IV pilus AB987_1837 ENOG4105CBC glutamate synthase AB987_1838 ENOG4105BZ8 glutamate synthase AB987_1840 ENOG4108V0P LemA family AB987_1841 ENOG4105HA9 of methanol dehydrogenase type AB987_1845 ENOG4108YSG O-Antigen polymerase AB987_1846 ENOG4108UQY Iron-storage protein AB987_1848 ENOG4105KME endoribonuclease L-psp AB987_1849 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) AB987_1851 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) AB987_1861 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) AB987_1864 ENOG4107IFA Lipase (EC 3.1.1.3) AB987_1865 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) AB987_1866 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) AB987_1871 ENOG4108JQ1 Dehydrogenase AB987_1872 ENOG4105CQB FAD linked oxidase domain protein AB987_1874 ENOG4105VRH Antibiotic biosynthesis monooxygenase AB987_1875 ENOG4105NF4 modulator of drug activity AB987_1878 ENOG4107QF7 multi-drug AB987_1879 ENOG4105EM2 membrane AB987_1880 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) AB987_1881 ENOG4105IPI Membrane AB987_1888 ENOG4108IQI permease AB987_1890 ENOG4105D82 Glutamate dehydrogenase AB987_1891 ENOG4105C8Y Acetylornithine aminotransferase AB987_1893 ENOG4105C26 Dehydrogenase AB987_1911 ENOG4105W87 Cbs domain AB987_1912 ENOG41067S9 phage shock protein C, PspC AB987_1914 ENOG4105CSU acyl-Coa dehydrogenase AB987_1917 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) AB987_1920 ENOG4105ECY inositol monophosphatase AB987_1921 ENOG4105C1J atp-dependent rna helicase AB987_1923 ENOG4105DHJ ABC, transporter AB987_1924 ENOG4105CY3 ABC transporter, permease AB987_1926 ENOG4105E3I toluene tolerance AB987_1929 ENOG4105D7N magnesium and cobalt transport protein CorA AB987_1930 ENOG4108URH decarboxylase AB987_1932 ENOG4105MJ2 Competence protein AB987_1933 ENOG4105CB5 ATP-dependent DNA helicase recG AB987_1937 ENOG4105C29 acyl-CoA thioesterase AB987_1938 ENOG4105CK2 sodium dicarboxylate symporter AB987_1941 ENOG4105KPV Transcriptional regulator AB987_1943 ENOG4105D7A ATP-binding protein AB987_1944 ENOG4105C28 cystathionine AB987_1945 ENOG41089BK Glutamine amido-transferase AB987_1967 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) AB987_1968 ENOG41067V7 50S ribosomal protein L36 AB987_1970 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) AB987_1975 ENOG4105C1G acyl-Coa dehydrogenase AB987_1982 ENOG4105VKU nucleicacid-binding protein AB987_1983 ENOG4105DGW oligopeptidase A AB987_1984 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) AB987_1993 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase AB987_1994 ENOG4108K2B transcriptional regulator AB987_1996 ENOG4107S2Z UPF0761 membrane protein AB987_1997 ENOG4105CS1 NAD(P)H quinone oxidoreductase AB987_2003 ENOG4105C9A Phoh family AB987_2005 ENOG4105E4C Lytic transglycosylase catalytic AB987_2011 ENOG4105D6S protein involved in catabolism of external DNA AB987_2012 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase AB987_2023 ENOG4105C1G acyl-Coa dehydrogenase AB987_2024 ENOG4108RZE Tetr family transcriptional regulator AB987_2028 ENOG4107QX3 carboxylase AB987_2029 ENOG4105C1G acyl-Coa dehydrogenase AB987_2033 ENOG4105KB2 stringent starvation protein b AB987_2034 ENOG4107MKT Stringent starvation protein a AB987_2035 ENOG4108UJD 30S ribosomal protein S9 AB987_2037 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) AB987_2038 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) AB987_2039 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) AB987_2043 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) AB987_2045 ENOG4107RZC phospholipase d AB987_2047 ENOG4105UYK outer membrane protein a AB987_2048 ENOG4108KHX Diguanylate cyclase AB987_2056 ENOG4107QN2 dihydrolipoyl dehydrogenase AB987_2058 ENOG4107QPB Beta-lactamase domain protein AB987_2059 ENOG4107U2T alpha beta AB987_2062 ENOG4105NAU thioesterase Superfamily protein AB987_2068 ENOG4105K9H YciI-like protein AB987_2070 ENOG4105DB7 PHP domain protein AB987_2071 ENOG4105FFC UPF0187 protein AB987_2073 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase AB987_2074 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) AB987_2075 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) AB987_2076 ENOG4105VIE preprotein translocase, subunit YajC AB987_2082 ENOG4105BZU Histidine kinase AB987_2083 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) AB987_2084 ENOG4105CM2 brancheD-chain amino acid aminotransferase AB987_2086 ENOG4107BJW polysaccharide deacetylase AB987_2087 ENOG4107TYR Glycosyl Transferase AB987_2089 ENOG4105C1B dTDP-glucose 4-6-dehydratase AB987_2090 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase AB987_2092 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase AB987_2099 ENOG4105UGU tonB-dependent Receptor AB987_2103 ENOG4108VY7 phosphate-starvation-inducible protein PsiE AB987_2104 ENOG4105CSU acyl-Coa dehydrogenase AB987_2105 ENOG4105CSU acyl-Coa dehydrogenase AB987_2107 ENOG4105EB3 Histidine kinase AB987_2108 ENOG4105E3W Two component transcriptional regulator (Winged helix family AB987_2109 ENOG4105CNG UPF0061 protein AB987_2113 ENOG4108WBT adenosyltransferase AB987_2116 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) AB987_2124 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase AB987_2128 ENOG4105D3R alkyl hydroperoxide reductase AB987_2131 ENOG4105CSH Transporter AB987_2132 ENOG4108UT2 hemolysin iii AB987_2137 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase AB987_2138 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase AB987_2139 ENOG4105CHU acetyl-coa acetyltransferase AB987_2140 ENOG4108R6W Transcriptional regulator, ARAC family AB987_2142 ENOG4105TW1 Carbohydrate-selective porin OprB AB987_2144 ENOG4105DZG Dehydrogenase AB987_2145 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) AB987_2147 ENOG410814C multidrug resistance protein AB987_2149 ENOG4105CHU acetyl-coa acetyltransferase AB987_2151 ENOG4108WHA ompa motb domain protein AB987_2153 ENOG4105E0Y RtcB Protein AB987_2154 ENOG4108IQI permease AB987_2156 ENOG4105C2W permease AB987_2160 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) AB987_2162 ENOG4108VX5 3-methyladenine DNA glycosylase AB987_2163 ENOG4105CHB tonB-dependent Receptor AB987_2164 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase AB987_2165 ENOG4108N2Y auxin Efflux AB987_2167 ENOG4105T95 Thiol disulfide interChange protein AB987_2168 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) AB987_2170 ENOG4105K78 MarR family Transcriptional regulator AB987_2171 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA AB987_2172 ENOG4105KWI UPF0339 protein AB987_2177 ENOG4108UNF response regulator AB987_2178 ENOG4105M3Z response regulator AB987_2179 ENOG4108ZGA chew protein AB987_2180 ENOG4105C8Q Methyl-accepting chemotaxis AB987_2181 ENOG4105CBS Chea signal transduction histidine kinase AB987_2184 ENOG4106HKS Entericidin EcnA/B family AB987_2186 ENOG4105WD1 Membrane AB987_2187 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein AB987_2195 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) AB987_2197 ENOG4105EM2 membrane AB987_2198 ENOG4105C2C drug resistance transporter, Bcr CflA AB987_2202 ENOG4105BZG amino acid carrier protein AB987_2203 ENOG4105D78 K07001 NTE family protein AB987_2204 ENOG4105C7B Threonine dehydratase AB987_2206 ENOG4105C9K Endothelin-converting enzyme 1 AB987_2211 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) AB987_2213 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) AB987_2214 ENOG4105DFF Rod shape-determining protein mreb AB987_2215 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) AB987_2217 ENOG4108Z03 MAF-like protein AB987_2218 ENOG4105C03 ribonuclease AB987_2220 ENOG4105D8T Acyltransferase AB987_2222 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein AB987_2224 ENOG4108X0B nad(p)h dehydrogenase (quinone) AB987_2229 ENOG4105CF7 AraC family transcriptional regulator AB987_2242 ENOG4105C85 amino acid AB987_2243 ENOG4105C7F AcnD-accessory protein PrpF AB987_2244 ENOG4105CTB Polyprenyl synthetase AB987_2245 ENOG4105MSB protein, conserved in bacteria AB987_2248 ENOG4105D78 K07001 NTE family protein AB987_2252 ENOG4105DIJ Phosphoethanolamine transferase AB987_2253 ENOG4105XJC Two component transcriptional regulator (Winged helix family AB987_2254 ENOG4105DHQ Histidine kinase AB987_2257 ENOG4108M0I Transcriptional regulator AB987_2262 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) AB987_2266 ENOG4105K8R UPF0145 protein AB987_2267 ENOG4105K8R UPF0145 protein AB987_2268 ENOG4105ENJ RND efflux system, outer membrane lipoprotein AB987_2269 ENOG4105BZS acriflavin resistance protein AB987_2270 ENOG4105C1P efflux transporter, rnd family, mfp subunit AB987_2271 ENOG410841Q phosphoesterase PA-phosphatase related protein AB987_2277 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) AB987_2280 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) AB987_2281 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) AB987_2282 ENOG4105KVH Transcriptional regulator AB987_2285 ENOG4105CUB amino acid AB987_2288 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) AB987_2289 ENOG41084BA UPF0250 protein AB987_2290 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AB987_2298 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit AB987_2299 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein AB987_2301 ENOG4105E33 succinate dehydrogenase AB987_2302 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 AB987_2303 ENOG4105C7S Dehydrogenase AB987_2304 ENOG4107QN2 dihydrolipoyl dehydrogenase AB987_2306 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha AB987_2308 ENOG4105CKW Inner membrane protein yedI AB987_2309 ENOG4105CGZ zinc metallopeptidase AB987_2310 ENOG4105EEQ Na H antiporter AB987_2315 ENOG4105D5G Transposase AB987_2317 ENOG4105MP0 transposase AB987_2320 ENOG4105PNM synthesis protein AB987_2323 ENOG41080TK Universal stress protein AB987_2325 ENOG4108UQ8 endoribonuclease L-psp AB987_2326 ENOG4108IG5 Transcriptional regulator AB987_2328 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain AB987_2329 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain AB987_2332 ENOG4105HBR Rna-binding protein AB987_2334 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) AB987_2335 ENOG4105EEI dihydropteroate synthase AB987_2345 ENOG4105CSH Transporter AB987_2347 ENOG4108JQ0 Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) AB987_2348 ENOG4105C6V Glycerol-3-phosphate dehydrogenase AB987_2351 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) AB987_2354 ENOG41080IJ Diacylglycerol kinase AB987_2356 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase AB987_2357 ENOG4105BZS acriflavin resistance protein AB987_2360 ENOG4105E4C Lytic transglycosylase catalytic AB987_2364 ENOG4108RRZ Transcription elongation factor GreB AB987_2366 ENOG4105DQ6 Transposase AB987_2375 ENOG4105MZU cell filamentation protein AB987_2377 ENOG4105CVR type I restriction-modification system AB987_2392 ENOG4105G6Z alkaline phosphatase AB987_2393 ENOG4105G6Z alkaline phosphatase AB987_2395 ENOG4108ZX5 transcriptional regulator AB987_2396 ENOG4105BZU Histidine kinase AB987_2399 ENOG4105E02 MotA TolQ exbB proton channel AB987_2400 ENOG4105M8F Biopolymer transport protein exbD tolR AB987_2402 ENOG4105DFP Integrase AB987_2404 ENOG4105CEY Amp-dependent synthetase and ligase AB987_2405 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) AB987_2417 ENOG4105BZW Glycerate kinase AB987_2418 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit AB987_2419 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) AB987_2422 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) AB987_2424 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) AB987_2425 ENOG4105C85 amino acid AB987_2427 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) AB987_2429 ENOG4105N14 lysine exporter protein LysE YggA AB987_2430 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) AB987_2431 ENOG4105BZJ Electron transfer flavoprotein AB987_2432 ENOG4105C10 Electron transfer flavoprotein AB987_2433 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AB987_2440 ENOG4107KET secretion protein, HlyD family AB987_2447 ENOG4105D60 lipoprotein releasing system transmembrane protein AB987_2448 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) AB987_2449 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 AB987_2451 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) AB987_2452 ENOG4107R6F Alpha Beta Hydrolase Fold protein AB987_2453 ENOG4108V3E phosphoribosylglycinamide formyltransferase AB987_2455 ENOG4105C02 permease AB987_2465 ENOG4105KCK Peptidoglycan-associated lipoprotein AB987_2466 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) AB987_2468 ENOG4105M8F Biopolymer transport protein exbD tolR AB987_2469 ENOG4105E02 MotA TolQ exbB proton channel AB987_2470 ENOG4107YD3 Thioesterase AB987_2471 ENOG4105CH2 amidohydrolase AB987_2472 ENOG4105CH2 amidohydrolase AB987_2476 ENOG4108ETH Formylglycinamide ribotide synthetase AB987_2477 ENOG4105C2C drug resistance transporter, Bcr CflA AB987_2479 ENOG4105EGD dinuclear metal center protein, YbgI family AB987_2480 ENOG4108UKI Enoyl-CoA hydratase AB987_2483 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen AB987_2486 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) AB987_2487 ENOG4107VRB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) AB987_2490 ENOG4107R11 Transcriptional regulator AB987_2491 ENOG4108IJ6 ABC transporter AB987_2493 ENOG4108I5D sulfate abc transporter AB987_2496 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein AB987_2497 ENOG4105YAZ 4-amino-4-deoxychorismate lyase AB987_2498 ENOG4105HHA aminodeoxychorismate lyase AB987_2501 ENOG4108IYU L-aspartate oxidase AB987_2502 ENOG4105C0H protease AB987_2504 ENOG41068WN AB987_2506 ENOG4105C3F Signal peptidase i AB987_2509 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) AB987_2511 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) AB987_2512 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) AB987_2513 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase AB987_2516 ENOG4105EMU Dehydrogenase AB987_2523 ENOG4105BZU Histidine kinase AB987_2525 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) AB987_2527 ENOG4105DTR rard protein AB987_2534 ENOG4107QS8 (LipO)protein AB987_2535 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) AB987_2536 ENOG4105EA8 2-Nitropropane dioxygenase AB987_2542 ENOG4107R8N Glycosyl transferase, family 2 AB987_2545 ENOG4105CVP deoxyribo-dipyrimidine photolyase AB987_2546 ENOG4108YZY peptidylprolyl cis-trans isomerase AB987_2547 ENOG4105CEP NADH dehydrogenase AB987_2548 ENOG4105DZ1 carboxypeptidase AB987_2550 ENOG4105E9K Isocitrate dehydrogenase AB987_2551 ENOG4108R99 pseudouridine synthase AB987_2556 ENOG4105CBP Major Facilitator AB987_2557 ENOG4105EGI Transcriptional regulator AB987_2558 ENOG4108ETY sodium dicarboxylate symporter AB987_2559 ENOG4105JAB phenazine biosynthesis protein, phzf family AB987_2565 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) AB987_2568 ENOG4105D3G Pseudouridine synthase AB987_2569 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) AB987_2573 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) AB987_2578 ENOG4108JPW Aminotransferase AB987_2579 ENOG4105DY8 decarboxylase AB987_2581 ENOG4105F7P transcriptional regulator AsnC family AB987_2582 ENOG4107RA9 decarboxylase AB987_2583 ENOG4105C85 amino acid AB987_2584 ENOG4105CVA phosphate AB987_2585 ENOG4105C8U phosphate abc transporter AB987_2587 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) AB987_2588 ENOG4105ERU peptidase AB987_2592 ENOG4107QTF adenylosuccinate lyase AB987_2596 ENOG4108Z0R Transferase AB987_2597 ENOG4105DZ1 carboxypeptidase AB987_2601 ENOG4108K5P (LipO)protein AB987_2602 ENOG4105EJC lysr family transcriptional regulator AB987_2603 ENOG4105DAN ATP-dependent protease AB987_2607 ENOG4105DHU Bile acid AB987_2609 ENOG41066DG (EAL) domain protein AB987_2611 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein AB987_2613 ENOG4105D22 carbon starvation protein AB987_2614 ENOG4105VCD cytoplasmic protein AB987_2621 ENOG4105C2I pirin domain protein AB987_2623 ENOG4105WWK YheO domain protein AB987_2626 ENOG4105CEY Amp-dependent synthetase and ligase AB987_2630 ENOG4108IPW abc transporter atp-binding protein AB987_2634 ENOG4105C0W non-ribosomal peptide synthetase AB987_2635 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase AB987_2636 ENOG4105WQI isochorismatase AB987_2639 ENOG4105BZ1 (ABC) transporter AB987_2640 ENOG4108JJ7 ABC transporter AB987_2646 ENOG4105NX3 Membrane AB987_2651 ENOG4105EUJ GTP cyclohydrolase i AB987_2653 ENOG4105C7W Xanthine dehydrogenase AB987_2659 ENOG4105CD8 aminopeptidase N AB987_2660 ENOG4105DDQ anthranilate synthase AB987_2662 ENOG4105DUX Transporter AB987_2663 ENOG4105C5F glutamine synthetase AB987_2665 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) AB987_2672 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) AB987_2673 ENOG4107QNR UPF0135 protein AB987_2674 ENOG4105C0H protease AB987_2676 ENOG4105C6K Malic enzyme AB987_2677 ENOG4105BZU Histidine kinase AB987_2678 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) AB987_2679 ENOG4105SYT Methylenetetrahydrofolate reductase AB987_2680 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) AB987_2683 ENOG4107QPN acyl-Coa dehydrogenase AB987_2684 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) AB987_2685 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) AB987_2688 ENOG4107RNU major facilitator superfamily MFS_1 AB987_2690 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) AB987_2691 ENOG4105CE9 30S ribosomal protein S2 AB987_2698 ENOG4105CVE Lytic murein transglycosylase AB987_2699 ENOG4105CNI cell division protein FtsW AB987_2702 ENOG4105E3A (ABC) transporter AB987_2703 ENOG4105DA5 (ABC) transporter AB987_2710 ENOG4105ENJ RND efflux system, outer membrane lipoprotein AB987_2712 ENOG4105ENT Efflux transporter rnd family, mfp subunit AB987_2714 ENOG4105E89 ABC transporter AB987_2715 ENOG4105DSP amino acid AbC transporter AB987_2716 ENOG4106YG3 ABC transporter AB987_2717 ENOG4108JEH abc transporter atp-binding protein AB987_2719 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding AB987_2720 ENOG4105CFP Peptidase U32 AB987_2721 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family AB987_2722 ENOG4105JAB phenazine biosynthesis protein, phzf family AB987_2723 ENOG4105DP0 ferredoxin-NADP reductase AB987_2724 ENOG4108R96 Methyltransferase, YaeB family AB987_2726 ENOG4107QHF type ii secretion system protein e AB987_2728 ENOG4105XJC Two component transcriptional regulator (Winged helix family AB987_2729 ENOG4105DHQ Histidine kinase AB987_2731 ENOG4105M6F mutator MutT protein AB987_2733 ENOG4105BZ4 penicillin-binding protein AB987_2734 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) AB987_2735 ENOG4105VUT cytoplasmic protein AB987_2737 ENOG4105CK2 sodium dicarboxylate symporter AB987_2738 ENOG4105C1G acyl-Coa dehydrogenase AB987_2740 ENOG4105CQC Prephenate dehydratase AB987_2741 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase AB987_2743 ENOG4105CIN aminoacyl-histidine dipeptidase AB987_2744 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) AB987_2750 ENOG4105M08 Membrane AB987_2751 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AB987_2753 ENOG4105VEQ Cold shock protein AB987_2754 ENOG4105C1J atp-dependent rna helicase AB987_2756 ENOG41069NU Nitroreductase AB987_2763 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase AB987_2766 ENOG4105C5I Dehydrogenase AB987_2767 ENOG4105ERG peptidase m48, ste24p AB987_2768 ENOG4105KTH gatB Yqey AB987_2769 ENOG4105VCC 30S ribosomal protein S21 AB987_2774 ENOG4105D9P serine threonine protein kinase AB987_2779 ENOG4105EVZ LysR family transcriptional regulator AB987_2780 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) AB987_2781 ENOG4105C26 Dehydrogenase AB987_2789 ENOG4105H4F exported protein AB987_2796 ENOG4105D6U Sodium Glutamate Symporter AB987_2798 ENOG4105JXH GntR family transcriptional regulator AB987_2809 ENOG4105CSH Transporter AB987_2815 ENOG4105DQ6 Transposase AB987_2821 ENOG4105F1S paraquat-inducible protein a AB987_2822 ENOG4105DY2 Paraquat-inducible protein b AB987_2830 ENOG4105CK2 sodium dicarboxylate symporter AB987_2832 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) AB987_2833 ENOG4108UMI ABC transporter, permease AB987_2834 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) AB987_2836 ENOG4105C12 Phosphoribosylglycinamide synthetase AB987_2837 ENOG4105DC1 bifunctional purine biosynthesis protein purh AB987_2849 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) AB987_2850 ENOG4105CDU Replicative dna helicase AB987_2855 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) AB987_2856 ENOG4105CCU oxidase (Subunit III) AB987_2858 ENOG4105BZ9 Cytochrome C oxidase, subunit I AB987_2859 ENOG4105E2S oxidase) subunit II AB987_2864 ENOG4107BJW polysaccharide deacetylase AB987_2866 ENOG4105CND Glycosyl transferase, family 2 AB987_2867 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD AB987_2869 ENOG4105DEN Luciferase family AB987_2872 ENOG4105CC0 LysR family Transcriptional regulator AB987_2875 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) AB987_2876 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component AB987_2877 ENOG4105GVF (ABC) transporter AB987_2880 ENOG4105C1G acyl-Coa dehydrogenase AB987_2882 ENOG4108MEJ flavin reductase domain protein AB987_2883 ENOG4105D06 uba thif-type nad fad binding protein AB987_2885 ENOG4105KRF dihydroneopterin aldolase AB987_2887 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) AB987_2888 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) AB987_2890 ENOG4105C08 Histidine kinase AB987_2891 ENOG4105EEX Two component transcriptional regulator (Winged helix family AB987_2892 ENOG4105CFQ glutamine synthetase AB987_2895 ENOG4107S74 Lysophospholipid transporter LplT AB987_2896 ENOG4105CFU surface antigen AB987_2899 ENOG4107QIJ Aconitate hydratase 2 AB987_2901 ENOG4105EYW Ion transport protein AB987_2902 ENOG4105F27 Major Facilitator AB987_2911 ENOG4105K70 DNA-binding protein AB987_2921 ENOG4105QIB mu-like prophage Flumu protein gp29 AB987_2922 ENOG4108QUU Morphogenesis Protein AB987_2923 ENOG4107XYH virion morphogenesis protein AB987_2926 ENOG4105EFV Major head subunit AB987_2946 ENOG4105DZ2 Transcriptional regulator AB987_2953 ENOG4105K8N protein family UPF0079, ATPase AB987_2954 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) AB987_2956 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) AB987_2957 ENOG4108TZV Membrane AB987_2958 ENOG4108RCM Nitroreductase AB987_2963 ENOG4105CX6 glutaminyL-tRNA synthetase AB987_2965 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) AB987_2966 ENOG4107FQ9 ethanolamine ammonia-lyase AB987_2967 ENOG4105CPD ethanolamine ammonia-lyase AB987_2968 ENOG4107R55 ethanolamine transporter AB987_2970 ENOG4107RR1 TRANSCRIPTIONal AB987_2972 ENOG4105C0A alcohol dehydrogenase AB987_2973 ENOG4107QUV Domain protein AB987_2975 ENOG4105F4I Transcriptional regulator AB987_2979 ENOG4105CD8 aminopeptidase N AB987_2983 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) AB987_2984 ENOG4105EW9 transcriptional regulator AsnC family AB987_2991 ENOG4105CNM Receptor AB987_2996 ENOG4105C5H ABC transporter AB987_2997 ENOG41081QV Universal stress protein AB987_3002 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic AB987_3004 ENOG4105DKK Benzoate AB987_3005 ENOG4105EW9 transcriptional regulator AsnC family AB987_3006 ENOG4108NIW Leucine export protein LeuE AB987_3007 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) AB987_3008 ENOG4105C5Q Transcriptional regulator AB987_3010 ENOG4105CHU acetyl-coa acetyltransferase AB987_3011 ENOG4105CHR reductase AB987_3016 ENOG4107QMP dna polymerase iii subunits gamma and tau AB987_3017 ENOG4105HSS phospholipase C AB987_3018 ENOG4105HSS phospholipase C AB987_3020 ENOG4105C0A alcohol dehydrogenase AB987_3026 ENOG4105CBC glutamate synthase AB987_3029 ENOG4105F9F transposase AB987_3032 ENOG4105D8G Major Facilitator superfamily AB987_3034 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase AB987_3035 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein AB987_3039 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AB987_3041 ENOG4107QZF nitrite reductase NADPH large subunit AB987_3042 ENOG4108IFG nitrite reductase, (NAD(P)H) AB987_3045 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) AB987_3046 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) AB987_3049 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) AB987_3050 ENOG4105CVM Molybdenum cofactor synthesis domain protein AB987_3052 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family AB987_3054 ENOG4105T38 integral membrane protein AB987_3058 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) AB987_3059 ENOG4105CMR udp-glucose 4-epimerase AB987_3071 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family AB987_3072 ENOG4105CUX Signal transduction histidine kinase AB987_3076 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) AB987_3077 ENOG4105KNE Phosphatidate cytidylyltransferase AB987_3079 ENOG4105DZP Membrane-associated zinc metalloprotease AB987_3084 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) AB987_3086 ENOG4105Y3E Modulates RecA activity (By similarity) AB987_3088 ENOG4105VEJ Heat shock protein AB987_3089 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 AB987_3095 ENOG4105F7P transcriptional regulator AsnC family AB987_3097 ENOG4105C85 amino acid AB987_3101 ENOG4105CHH sulfate transporter AB987_3103 ENOG4105D8V Glucose sorbosone dehydrogenase AB987_3105 ENOG4105BZU Histidine kinase AB987_3108 ENOG4105DM4 PTS System AB987_3109 ENOG4105DE4 1-phosphofructokinase AB987_3110 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) AB987_3114 ENOG4105CWM branched-chain amino acid transport system II carrier protein AB987_3115 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) AB987_3116 ENOG4105CC0 LysR family Transcriptional regulator AB987_3118 ENOG4105M2J Glutaredoxin AB987_3119 ENOG4105C8Y Acetylornithine aminotransferase AB987_3120 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) AB987_3126 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) AB987_3128 ENOG41068P6 UPF0319 protein AB987_3130 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii AB987_3131 ENOG4105C4M (Ubiquinol oxidase) subunit I AB987_3132 ENOG4105PV3 Inner membrane protein yqiJ AB987_3135 ENOG4105E0K tonB-dependent siderophore receptor AB987_3137 ENOG4105HDD phospholipase AB987_3138 ENOG4105CZN Potassium uptake protein AB987_3140 ENOG4105C7B Threonine dehydratase AB987_3147 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) AB987_3148 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AB987_3150 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) AB987_3153 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase AB987_3162 ENOG4107VMU Membrane AB987_3163 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) AB987_3165 ENOG4107QP7 CoA-transferase subunit A AB987_3166 ENOG4107QNJ CoA-transferase subunit B AB987_3167 ENOG4105CHU acetyl-coa acetyltransferase AB987_3168 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase AB987_3169 ENOG4105F2Z 3-oxoadipate enol-lactonase AB987_3170 ENOG4105D2S major facilitator superfamily AB987_3171 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase AB987_3172 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta AB987_3173 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha AB987_3174 ENOG4105FF2 Type I DHQase AB987_3175 ENOG4106JPM 3-dehydroshikimate dehydratase AB987_3176 ENOG4105TW1 Carbohydrate-selective porin OprB AB987_3177 ENOG4105DZG Dehydrogenase AB987_3179 ENOG4105MD1 YeeE YedE family protein AB987_3182 ENOG4107HP6 Transcriptional regulator AB987_3183 ENOG4108PTX LysR family Transcriptional regulator AB987_3184 ENOG4105C1G acyl-Coa dehydrogenase AB987_3189 ENOG4105DNH Major Facilitator AB987_3192 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) AB987_3196 ENOG4105FUY alpha subunit AB987_3198 ENOG4105CHR reductase AB987_3202 ENOG4105F11 amine oxidase AB987_3204 ENOG4105C26 Dehydrogenase AB987_3205 ENOG4105F2Z 3-oxoadipate enol-lactonase AB987_3206 ENOG4105CHU acetyl-coa acetyltransferase AB987_3207 ENOG4107QNJ CoA-transferase subunit B AB987_3208 ENOG4107QP7 CoA-transferase subunit A AB987_3210 ENOG4105NN7 muconolactone delta-isomerase AB987_3211 ENOG4105DTQ mandelate racemase muconate lactonizing AB987_3212 ENOG4108KB2 LysR family Transcriptional regulator AB987_3214 ENOG4107EJG GntR family transcriptional regulator AB987_3219 ENOG4105CZJ Aldehyde dehydrogenase AB987_3222 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase AB987_3225 ENOG4108Z6Z Transcriptional regulator AB987_3230 ENOG4107Z3H Transcriptional regulator, TetR family AB987_3232 ENOG4105CHJ isochorismatase hydrolase AB987_3233 ENOG4105EJC lysr family transcriptional regulator AB987_3234 ENOG4105D8V Glucose sorbosone dehydrogenase AB987_3235 ENOG4105CKD glutathione-regulated potassium-efflux system protein AB987_3237 ENOG4105CH2 amidohydrolase AB987_3251 ENOG4105FDP GntR family transcriptional regulator AB987_3254 ENOG4106KR7 LysR family Transcriptional regulator AB987_3259 ENOG4105MSY salicylate hydroxylase AB987_3264 ENOG4105CW7 secretion protein, HlyD family AB987_3267 ENOG4105CZJ Aldehyde dehydrogenase AB987_3268 ENOG4105C01 Dihydroxy-acid dehydratase AB987_3270 ENOG4105DDW LysR family Transcriptional regulator AB987_3271 ENOG4105EXW epimerase dehydratase AB987_3274 ENOG4105EHG Permease protein AB987_3275 ENOG4105E0A ABC, transporter AB987_3279 ENOG4105C5T Phosphoribosyl pyrophosphate synthase AB987_3289 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) AB987_3302 ENOG4105XUP Phage derived protein Gp49-like (DUF891) AB987_3312 ENOG4105BZU Histidine kinase AB987_3319 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AB987_3322 ENOG4105VN1 Heat shock protein AB987_3325 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein AB987_3326 ENOG4108WUH Transcriptional regulator, TetR family AB987_3327 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase AB987_3329 ENOG4108I6A alcohol dehydrogenase AB987_3331 ENOG4105C4W S-formylglutathione hydrolase AB987_3334 ENOG4105MP0 transposase AB987_3337 ENOG4105YES addiction module antidote protein AB987_3339 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) AB987_3342 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) AB987_3343 ENOG4105BZ1 (ABC) transporter AB987_3344 ENOG4105BZ1 (ABC) transporter AB987_3348 ENOG4108JQ7 (ABC) transporter AB987_3349 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AB987_3351 ENOG4105DEF Extracellular solute-binding protein, family 5 AB987_3360 ENOG4107RZC phospholipase d AB987_3364 ENOG4108IGT Dipeptidase AB987_3371 ENOG4107T31 5'-nucleotidase AB987_3374 ENOG4105WQI isochorismatase AB987_3375 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase AB987_3376 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) AB987_3377 ENOG4105E0C molybdate abc transporter AB987_3378 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein AB987_3379 ENOG4105F4R Transcriptional regulator mode AB987_3380 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit AB987_3381 ENOG4108YS2 small subunit AB987_3382 ENOG4105F57 Anthranilate dioxygenase reductase AB987_3390 ENOG4105CHR reductase AB987_3392 ENOG4105D5G Transposase AB987_3394 ENOG4105D2S major facilitator superfamily AB987_3395 ENOG4105CF7 AraC family transcriptional regulator AB987_3396 ENOG4105DTD Dehydrogenase AB987_3397 ENOG4105CY2 Citrate transporter AB987_3398 ENOG4105CY2 Citrate transporter AB987_3400 ENOG4108IND Tetr family transcriptional regulator AB987_3404 ENOG4108M0I Transcriptional regulator AB987_3407 ENOG4105CRW Short chain fatty acid transporter AB987_3408 ENOG4105CHU acetyl-coa acetyltransferase AB987_3410 ENOG4107YNJ LysR family Transcriptional regulator AB987_3413 ENOG4108IJ0 Aspartate ammonia-lyase AB987_3415 ENOG4105CSH Transporter AB987_3420 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component AB987_3421 ENOG4106FTQ Taurine ABC transporter, periplasmic AB987_3424 ENOG4105FDP GntR family transcriptional regulator AB987_3426 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) AB987_3427 ENOG4105KVH Transcriptional regulator AB987_3428 ENOG4105UEI Transcriptional Regulator AraC Family AB987_3431 ENOG4108VCT Sulfite exporter TauE/SafE AB987_3433 ENOG4107S76 domain protein AB987_3435 ENOG4105FFC UPF0187 protein AB987_3437 ENOG4105CHR reductase AB987_3440 ENOG4105CPP Dehydrogenase, E1 component AB987_3441 ENOG4107R0V Pyruvate dehydrogenase AB987_3443 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) AB987_3446 ENOG4105BZU Histidine kinase AB987_3448 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) AB987_3449 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) AB987_3458 ENOG4105F9F transposase AB987_3459 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) AB987_3462 ENOG4105C28 cystathionine AB987_3464 ENOG4105F2W methyltransferase AB987_3474 ENOG4105K59 histidine triad (HIT) protein AB987_3479 ENOG4107QWP ABC-2 type transporter AB987_3480 ENOG4107QWP ABC-2 type transporter AB987_3481 ENOG4105CJ1 ABC, transporter AB987_3483 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) AB987_3484 ENOG4105CNM Receptor AB987_3487 ENOG4107TSN permease AB987_3488 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) AB987_3491 ENOG4107TB6 phosphoglycerate mutase AB987_3492 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) AB987_3493 ENOG4108YZT Adenosylcobinamide kinase AB987_3503 ENOG4105JSC dimethylmenaquinone methyltransferase AB987_3505 ENOG4105DJU Siderophore biosynthesis protein AB987_3506 ENOG4105DUU IucA IucC family protein AB987_3507 ENOG4105C0R drug resistance transporter emrb qaca subfamily AB987_3511 ENOG4108Z66 YbaK ebsC protein AB987_3514 ENOG4105C1G acyl-Coa dehydrogenase AB987_3515 ENOG4105C1G acyl-Coa dehydrogenase AB987_3516 ENOG4105EEF Alkane 1-monooxygenase AB987_3517 ENOG4105E7U AraC family transcriptional regulator AB987_3518 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) AB987_3519 ENOG4105K70 DNA-binding protein AB987_3522 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family AB987_3524 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins AB987_3525 ENOG4108Z4V iron-sulfur cluster assembly AB987_3528 ENOG4108ZIT Ferredoxin, 2FE-2S AB987_3529 ENOG4105F8J Adenylate Guanylate cyclase AB987_3531 ENOG4108JA2 transcriptioN-repair coupling factor AB987_3535 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) AB987_3536 ENOG4105K4T epimerase AB987_3539 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase AB987_3546 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AB987_3548 ENOG4105DGW oligopeptidase A AB987_3555 ENOG4105SG9 biopolymer transport protein, ExbD AB987_3557 ENOG4107QP3 malate synthase g AB987_3558 ENOG4105D6Z AFG1 family ATPase AB987_3562 ENOG4107RN6 Monooxygenase AB987_3563 ENOG4105F95 Monooxygenase AB987_3564 ENOG4105D5G Transposase AB987_3568 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) AB987_3569 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) AB987_3573 ENOG4108Z6B deaminase AB987_3577 ENOG4108RTD type II secretion system protein K AB987_3582 ENOG4105F8V Hydrolase, tatD family AB987_3584 ENOG4107QRG dna polymerase iii AB987_3586 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) AB987_3587 ENOG4105BZ1 (ABC) transporter AB987_3590 ENOG4105FA0 parb-like partition protein AB987_3591 ENOG4107QJE Chromosome Partitioning Protein AB987_3593 ENOG4108S0S Nucleotidyl transferase AB987_3594 ENOG4105EHM Aminoglycoside phosphotransferase AB987_3595 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) AB987_3596 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) AB987_3597 ENOG4105D2N Aldolase AB987_3601 ENOG4108UHJ MAF-like protein AB987_3602 ENOG4105EZE Cupin 4 family protein AB987_3604 ENOG41080HT Transcriptional regulator, arsr family AB987_3606 ENOG4105XPP Protein of unknown function (DUF1275) AB987_3607 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme AB987_3608 ENOG4105BZ1 (ABC) transporter AB987_3610 ENOG4108ZX5 transcriptional regulator AB987_3612 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) AB987_3613 ENOG4105CK7 Sodium proline symporter AB987_3614 ENOG4105EW9 transcriptional regulator AsnC family AB987_3615 ENOG4105C26 Dehydrogenase AB987_3616 ENOG4105YGK Pfam:UPF0157 AB987_3619 ENOG4108T58 Mg2 transport protein CorA AB987_3621 ENOG4108YYC ycei family AB987_3623 ENOG4105CV1 Transketolase (EC 2.2.1.1) AB987_3629 ENOG4108HWY Beta-lactamase AB987_3634 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) AB987_3635 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) AB987_3643 ENOG4105F9F transposase AB987_3644 ENOG41067SE Tetr family transcriptional regulator AB987_3649 ENOG4105EW9 transcriptional regulator AsnC family AB987_3651 ENOG4105CDA abc transporter atp-binding protein AB987_3652 ENOG4105DRP amino acid AbC transporter AB987_3653 ENOG4105EAD ABC transporter AB987_3657 ENOG4107T8P acyl-Coa dehydrogenase AB987_3660 ENOG4105D01 (LipO)protein AB987_3662 ENOG4105D01 (LipO)protein AB987_3663 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) AB987_3664 ENOG4108UMI ABC transporter, permease AB987_3665 ENOG4105C3G gtp-binding protein AB987_3670 ENOG4108UMN azlc family AB987_3671 ENOG4105ZED uncharacterized protein ygaH AB987_3677 ENOG4105E7U AraC family transcriptional regulator AB987_3678 ENOG4108V06 Glutathione peroxidase AB987_3680 ENOG4105CHM Aminotransferase AB987_3683 ENOG4105C0B DNA polymerase III (alpha subunit) AB987_3688 ENOG4108JU3 Alkyl hydroperoxide reductase AB987_3691 ENOG4108KB2 LysR family Transcriptional regulator AB987_3692 ENOG4105D6J arsenicaL-resistance protein AB987_3693 ENOG41082YX Transcriptional regulator, arsr family AB987_3696 ENOG4105CPN adenine deaminase AB987_3699 ENOG4105F9F transposase AB987_3702 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease AB987_3704 ENOG4105E2B Taurine dioxygenase AB987_3705 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component AB987_3706 ENOG4108IY8 ABC, transporter AB987_3707 ENOG4106FTQ Taurine ABC transporter, periplasmic AB987_3709 ENOG4105C54 Major Facilitator superfamily AB987_3714 ENOG4105C4M (Ubiquinol oxidase) subunit I AB987_3715 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii AB987_3717 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family AB987_3718 ENOG4108K70 Transcriptional regulator AB987_3721 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase AB987_3722 ENOG4105PSI phosphoribosyl-dephospho-CoA transferase AB987_3725 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) AB987_3726 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase AB987_3728 ENOG4105ETT transcriptional Regulator, LysR family AB987_3730 ENOG4105DXI Major Facilitator superfamily AB987_3734 ENOG41067MG lrgb family AB987_3735 ENOG4105VAW lrga family AB987_3736 ENOG4105CMU LysR family (Transcriptional regulator AB987_3737 ENOG4108SHQ Glutathione S-transferase AB987_3738 ENOG4105CYM Glutathione S-transferase AB987_3739 ENOG4105CBN LysR family transcriptional regulator AB987_3740 ENOG4105CHR reductase AB987_3742 ENOG4105D7W serine acetyltransferase AB987_3743 ENOG4105ESN nucleotide-binding protein AB987_3744 ENOG4105ESN nucleotide-binding protein AB987_3745 ENOG4105C9B Cysteine desulfurase AB987_3747 ENOG4105EXG Transcriptional regulator AB987_3750 ENOG4105CT1 (ABC) transporter AB987_3751 ENOG4107RP9 extracellular solute-binding protein, family 3 AB987_3752 ENOG4105CDA abc transporter atp-binding protein AB987_3753 ENOG4108HW4 amino acid AbC transporter AB987_3754 ENOG4105EAD ABC transporter AB987_3756 ENOG4107RTG Major Facilitator superfamily AB987_3757 ENOG4105EQ2 LysR family Transcriptional regulator AB987_3759 ENOG4105ENX hydrolase AB987_3760 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase AB987_3761 ENOG4105BZU Histidine kinase AB987_3763 ENOG4105EW9 transcriptional regulator AsnC family AB987_3765 ENOG4105KT5 UmuD protein AB987_3770 ENOG4105CYX Short-chain dehydrogenase reductase Sdr AB987_3780 ENOG4105HEI LysR family (Transcriptional regulator AB987_3787 ENOG4105CH6 catalase AB987_3809 ENOG4105EE5 Membrane protein terC AB987_3810 ENOG4105W2W Cytotoxic translational repressor of toxin-antitoxin stability system