locus-tag	class	description
H2783_00010	COG0592	DNA-directed DNA polymerase activity
H2783_00020	COG0187	DNA topoisomerase II activity
H2783_00030	COG0586	Pfam SNARE associated Golgi protein
H2783_00035	COG0488	(ABC) transporter
H2783_00060	COG0596	Alpha beta hydrolase
H2783_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H2783_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H2783_00110	COG0733	neurotransmitter:sodium symporter activity
H2783_00150	COG2233	PERMEase
H2783_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H2783_00200	COG2814	Major facilitator Superfamily
H2783_00205	COG0656	L-ascorbic acid biosynthetic process
H2783_00210	COG0583	DNA-binding transcription factor activity
H2783_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H2783_00230	COG1064	alcohol dehydrogenase
H2783_00235	COG2818	Glycosylase
H2783_00250	COG1194	a g-specific adenine glycosylase
H2783_00270	COG2983	Belongs to the UPF0260 family
H2783_00275	COG2133	pyrroloquinoline quinone binding
H2783_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H2783_00285	COG2116	formate transmembrane transporter activity
H2783_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H2783_00310	COG1335	isochorismatase
H2783_00315	COG0385	Bile acid
H2783_00320	COG0534	Mate efflux family protein
H2783_00325	COG1683	Conserved Protein
H2783_00345	COG0625	glutathione transferase activity
H2783_00355	COG1113	amino acid transport
H2783_00365	COG0523	cobalamin synthesis protein
H2783_00375	COG2188	Transcriptional regulator
H2783_00405	COG0010	Belongs to the arginase family
H2783_00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H2783_00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H2783_00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H2783_00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H2783_00540	COG0534	Mate efflux family protein
H2783_00545	COG0436	Aminotransferase
H2783_00550	COG2733	membrane
H2783_00565	COG2918	glutathione biosynthetic process
H2783_00580	COG1388	LysM domain
H2783_00580	COG0791	NLP P60 protein
H2783_00595	COG3150	esterase
H2783_00605	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_00610	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
H2783_00620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H2783_00630	COG2233	PERMEase
H2783_00635	COG2351	hydroxyisourate hydrolase activity
H2783_00670	COG3706	GGDEF domain
H2783_00685	COG1393	Belongs to the ArsC family
H2783_00690	COG0708	Exodeoxyribonuclease III
H2783_00710	COG0189	ligase activity
H2783_00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H2783_00740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H2783_00755	COG4942	peptidase
H2783_00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
H2783_00775	COG2119	membrane
H2783_00780	COG4774	siderophore transport
H2783_00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H2783_00785	COG0426	domain, Protein
H2783_00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H2783_00830	COG1902	pentaerythritol trinitrate reductase activity
H2783_00835	COG1519	Transferase
H2783_00840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H2783_00845	COG0668	transmembrane transport
H2783_00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H2783_00860	COG1335	isochorismatase
H2783_00865	COG1522	sequence-specific DNA binding
H2783_00870	COG3328	transposase activity
H2783_00895	COG0784	Response regulator, receiver
H2783_00895	COG2198	Histidine kinase
H2783_00895	COG2205	protein histidine kinase activity
H2783_00900	COG3162	membrane
H2783_00905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H2783_00915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H2783_00935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H2783_00940	COG1309	transcriptional regulator
H2783_00960	COG0351	phosphomethylpyrimidine kinase
H2783_00960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H2783_00960	COG0352	thiamine-phosphate diphosphorylase activity
H2783_00970	COG2814	Major facilitator Superfamily
H2783_00985	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H2783_00995	COG1113	amino acid transport
H2783_01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H2783_01010	COG1012	belongs to the aldehyde dehydrogenase family
H2783_01020	COG1335	isochorismatase
H2783_01050	COG2814	Major facilitator Superfamily
H2783_01055	COG0583	DNA-binding transcription factor activity
H2783_01075	COG0667	Aldo Keto reductase
H2783_01105	COG1733	regulation of RNA biosynthetic process
H2783_01110	COG2249	NAD(P)H dehydrogenase (quinone) activity
H2783_01115	COG4372	Transposase
H2783_01190	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H2783_01205	COG2329	Antibiotic biosynthesis monooxygenase
H2783_01235	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H2783_01265	COG0427	acetyl-CoA hydrolase
H2783_01290	COG0659	secondary active sulfate transmembrane transporter activity
H2783_01295	COG4221	oxidoreductase activity
H2783_01300	COG2873	o-acetylhomoserine
H2783_01305	COG0488	(ABC) transporter
H2783_01390	COG0833	amino acid
H2783_01435	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H2783_01440	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H2783_01455	COG2226	methyltransferase
H2783_01505	COG0067	glutamate synthase
H2783_01505	COG0069	glutamate synthase activity
H2783_01505	COG0070	glutamate synthase
H2783_01510	COG0493	'glutamate synthase
H2783_01520	COG1704	LemA family
H2783_01525	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H2783_01540	COG3328	transposase activity
H2783_01550	COG3307	-O-antigen
H2783_01570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H2783_01585	COG0194	GDP metabolic process
H2783_01635	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H2783_01655	COG5380	lipid catabolic process
H2783_01660	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H2783_01685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H2783_01690	COG0277	FAD linked oxidase domain protein
H2783_01700	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H2783_01705	COG2249	NAD(P)H dehydrogenase (quinone) activity
H2783_01720	COG1289	transmembrane transporter activity
H2783_01730	COG0628	permease
H2783_01735	COG1192	Involved in chromosome partitioning
H2783_01765	COG0833	amino acid
H2783_01770	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H2783_01775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H2783_01785	COG1012	belongs to the aldehyde dehydrogenase family
H2783_01825	COG0583	DNA-binding transcription factor activity
H2783_01870	COG0517	IMP dehydrogenase activity
H2783_01875	COG1983	PspC domain protein
H2783_01885	COG1960	acyl-CoA dehydrogenase activity
H2783_01900	COG0408	coproporphyrinogen oxidase activity
H2783_01920	COG0513	Belongs to the DEAD box helicase family
H2783_01930	COG1127	ABC transporter
H2783_01935	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H2783_01945	COG2854	intermembrane phospholipid transfer
H2783_01955	COG0598	Magnesium transport protein CorA
H2783_01965	COG0494	nUDIX hydrolase
H2783_01970	COG1040	competence protein
H2783_01975	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H2783_01995	COG1946	Acyl-CoA thioesterase
H2783_02000	COG1301	dicarboxylic acid transport
H2783_02015	COG1959	2 iron, 2 sulfur cluster binding
H2783_02020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H2783_02020	COG1017	nitric oxide dioxygenase activity
H2783_02025	COG0433	COG0433 Predicted ATPase
H2783_02030	COG0626	cystathionine gamma-synthase activity
H2783_02185	COG1960	acyl-CoA dehydrogenase activity
H2783_02190	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H2783_02220	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H2783_02225	COG0339	signal peptide processing
H2783_02230	COG0557	exoribonuclease II activity
H2783_02275	COG0179	Fumarylacetoacetate (FAA) hydrolase
H2783_02280	COG2169	Transcriptional regulator
H2783_02285	COG0697	spore germination
H2783_02290	COG1295	ribonuclease BN
H2783_02325	COG1702	phosphate starvation-inducible protein PhoH
H2783_02335	COG0741	lytic transglycosylase activity
H2783_02335	COG0739	heme binding
H2783_02335	COG1196	nuclear chromosome segregation
H2783_02365	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H2783_02370	COG1183	phosphatidylcholine synthase activity
H2783_02415	COG1960	acyl-CoA dehydrogenase activity
H2783_02420	COG1309	transcriptional regulator
H2783_02435	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H2783_02440	COG1960	acyl-CoA dehydrogenase activity
H2783_02460	COG2969	positive regulation of protein catabolic process
H2783_02470	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H2783_02485	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H2783_02490	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H2783_02510	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H2783_02520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H2783_02525	COG1408	metallophosphoesterase
H2783_02535	COG2199	diguanylate cyclase activity
H2783_02595	COG1607	acyl-coa hydrolase
H2783_02625	COG2350	Protein conserved in bacteria
H2783_02635	COG0613	PHP domain protein
H2783_02640	COG3781	membrane
H2783_02650	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H2783_02655	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H2783_02665	COG1862	Preprotein translocase
H2783_02710	COG2205	protein histidine kinase activity
H2783_02715	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H2783_02735	COG0726	polysaccharide deacetylase
H2783_02740	COG0463	Glycosyl transferase, family 2
H2783_02745	COG0438	transferase activity, transferring glycosyl groups
H2783_02810	COG0625	glutathione transferase activity
H2783_02815	COG0583	DNA-binding transcription factor activity
H2783_02820	COG1960	acyl-CoA dehydrogenase activity
H2783_02825	COG1960	acyl-CoA dehydrogenase activity
H2783_02835	COG2205	protein histidine kinase activity
H2783_02840	COG0745	RESPONSE REGULATOR receiver
H2783_02845	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H2783_02865	COG2096	Adenosyltransferase
H2783_02915	COG0285	dihydrofolate synthase activity
H2783_02935	COG0450	alkyl hydroperoxide reductase
H2783_02950	COG0477	Major facilitator Superfamily
H2783_02955	COG1272	protein, Hemolysin III
H2783_02985	COG0183	Belongs to the thiolase family
H2783_02990	COG2207	Transcriptional regulator
H2783_03010	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H2783_03030	COG0183	Belongs to the thiolase family
H2783_03040	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H2783_03040	COG2885	chlorophyll binding
H2783_03050	COG1690	Belongs to the RtcB family
H2783_03055	COG0833	amino acid
H2783_03065	COG2233	PERMEase
H2783_03070	COG1217	gtp-binding protein TYPA
H2783_03095	COG2094	Belongs to the DNA glycosylase MPG family
H2783_03100	COG4772	TonB-dependent receptor
H2783_03105	COG1902	pentaerythritol trinitrate reductase activity
H2783_03120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H2783_03125	COG0354	folic acid binding
H2783_03135	COG3189	MarR family transcriptional regulator
H2783_03140	COG2824	Alkylphosphonate utilization operon protein PhnA
H2783_03145	COG3422	double-strand break repair
H2783_03185	COG0840	transmembrane signaling receptor activity
H2783_03205	COG5510	response to toxic substance
H2783_03215	COG2832	Protein of unknown function (DUF454)
H2783_03220	COG1376	ErfK ybiS ycfS ynhG family protein
H2783_03260	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H2783_03270	COG1289	transmembrane transporter activity
H2783_03275	COG2814	Major facilitator Superfamily
H2783_03295	COG1115	amino acid carrier protein
H2783_03300	COG1752	Esterase of the alpha-beta hydrolase superfamily
H2783_03305	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H2783_03310	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H2783_03340	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H2783_03350	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H2783_03355	COG1077	Cell shape determining protein MreB Mrl
H2783_03360	COG1792	Involved in formation and maintenance of cell shape
H2783_03365	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H2783_03370	COG0424	maF-like protein
H2783_03375	COG1530	ribonuclease E activity
H2783_03385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2783_03395	COG0560	Phosphoserine phosphatase
H2783_03405	COG2249	NAD(P)H dehydrogenase (quinone) activity
H2783_03430	COG2207	Transcriptional regulator
H2783_03450	COG1113	amino acid transport
H2783_03455	COG2828	Protein conserved in bacteria
H2783_03460	COG0142	geranyltranstransferase activity
H2783_03465	COG2315	Protein conserved in bacteria
H2783_03480	COG1752	Esterase of the alpha-beta hydrolase superfamily
H2783_03500	COG2194	sulfuric ester hydrolase activity
H2783_03505	COG0745	RESPONSE REGULATOR receiver
H2783_03510	COG0642	Histidine kinase
H2783_03520	COG0004	ammonium transporteR
H2783_03525	COG0583	DNA-binding transcription factor activity
H2783_03545	COG0525	valine-tRNA ligase activity
H2783_03555	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_03565	COG0393	Putative heavy-metal-binding
H2783_03570	COG0393	Putative heavy-metal-binding
H2783_03575	COG1538	Outer membrane efflux protein
H2783_03585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H2783_03590	COG0671	phosphoesterase, PA-phosphatase related
H2783_03620	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H2783_03635	COG1648	precorrin-2 dehydrogenase activity
H2783_03635	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H2783_03640	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H2783_03645	COG1733	regulation of RNA biosynthetic process
H2783_03655	COG0531	amino acid
H2783_03670	COG0321	lipoyl(octanoyl) transferase activity
H2783_03675	COG2921	Belongs to the UPF0250 family
H2783_03715	COG2009	succinate dehydrogenase
H2783_03720	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H2783_03725	COG1053	succinate dehydrogenase
H2783_03730	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H2783_03755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H2783_03775	COG2354	Protein conserved in bacteria
H2783_03780	COG2321	neutral zinc metallopeptidase
H2783_03810	COG2843	Capsule synthesis protein
H2783_03825	COG0589	response to stress
H2783_03845	COG0505	Belongs to the CarA family
H2783_03870	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H2783_03875	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H2783_03925	COG0477	Major facilitator Superfamily
H2783_03930	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H2783_03945	COG1597	lipid kinase activity
H2783_03950	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H2783_03975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H2783_03980	COG0584	glycerophosphoryl diester phosphodiesterase
H2783_04000	COG0741	lytic transglycosylase activity
H2783_04020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H2783_04035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2783_04060	COG0778	Nitroreductase
H2783_04075	COG1929	Belongs to the glycerate kinase type-1 family
H2783_04080	COG0243	molybdopterin cofactor binding
H2783_04085	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H2783_04090	COG3339	Conserved Protein
H2783_04100	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
H2783_04115	COG1113	amino acid transport
H2783_04125	COG0019	diaminopimelate decarboxylase activity
H2783_04135	COG1280	lysine exporter protein (LysE YggA)
H2783_04140	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H2783_04170	COG0463	Glycosyl transferase, family 2
H2783_04190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H2783_04225	COG4591	ABC-type transport system involved in lipoprotein release permease component
H2783_04230	COG1136	(ABC) transporter
H2783_04235	COG2333	competence protein COMEC
H2783_04235	COG0658	competence protein
H2783_04245	COG0616	signal peptide processing
H2783_04245	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H2783_04250	COG0596	Alpha beta hydrolase
H2783_04255	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H2783_04265	COG0628	permease
H2783_04310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H2783_04330	COG0823	Involved in the tonB-independent uptake of proteins
H2783_04350	COG0824	Thioesterase
H2783_04355	COG1473	amidohydrolase
H2783_04375	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H2783_04375	COG0047	phosphoribosylformylglycinamidine synthase activity
H2783_04380	COG2814	Major facilitator Superfamily
H2783_04390	COG1024	Enoyl-CoA hydratase
H2783_04395	COG1056	cytidyltransferase-related domain
H2783_04395	COG1051	belongs to the nudix hydrolase family
H2783_04405	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H2783_04420	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H2783_04435	COG4625	pathogenesis
H2783_04440	COG0583	DNA-binding transcription factor activity
H2783_04445	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H2783_04450	COG4208	sulfate ABC transporter
H2783_04455	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H2783_04465	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H2783_04470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H2783_04475	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H2783_04495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H2783_04510	COG0681	Belongs to the peptidase S26 family
H2783_04525	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H2783_04535	COG1381	Involved in DNA repair and RecF pathway recombination
H2783_04540	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H2783_04550	COG4221	oxidoreductase activity
H2783_04580	COG0436	Aminotransferase
H2783_04600	COG0556	nucleotide-excision repair
H2783_04655	COG2070	2-Nitropropane dioxygenase
H2783_04685	COG1215	transferase activity, transferring glycosyl groups
H2783_04700	COG0415	Belongs to the DNA photolyase family
H2783_04710	COG1252	NADH dehydrogenase
H2783_04715	COG1686	Belongs to the peptidase S11 family
H2783_04730	COG1187	pseudouridine synthase activity
H2783_04755	COG0477	Major facilitator Superfamily
H2783_04760	COG0583	DNA-binding transcription factor activity
H2783_04765	COG1823	symporter activity
H2783_04775	COG0612	Peptidase, M16
H2783_04800	COG0352	thiamine-phosphate diphosphorylase activity
H2783_04835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H2783_04850	COG1309	transcriptional regulator
H2783_04860	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H2783_04865	COG0076	glutamate decarboxylase activity
H2783_04875	COG1522	sequence-specific DNA binding
H2783_04880	COG3961	Belongs to the TPP enzyme family
H2783_04885	COG1113	amino acid transport
H2783_04890	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H2783_04895	COG0573	inorganic phosphate transmembrane transporter activity
H2783_04905	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H2783_04910	COG0616	signal peptide processing
H2783_04945	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H2783_04950	COG1686	Belongs to the peptidase S11 family
H2783_04975	COG0583	DNA-binding transcription factor activity
H2783_04980	COG1067	ATP-dependent peptidase activity
H2783_05025	COG1966	Carbon starvation protein
H2783_05030	COG2879	small protein
H2783_05060	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H2783_05060	COG2508	Transcriptional regulator
H2783_05090	COG4372	Transposase
H2783_05100	COG1113	amino acid transport
H2783_05105	COG0583	DNA-binding transcription factor activity
H2783_05110	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H2783_05115	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H2783_05125	COG1012	belongs to the aldehyde dehydrogenase family
H2783_05130	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H2783_05135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H2783_05135	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
H2783_05160	COG4372	Transposase
H2783_05190	COG2814	Major facilitator Superfamily
H2783_05195	COG4948	Mandelate Racemase Muconate Lactonizing
H2783_05205	COG1309	transcriptional regulator
H2783_05225	COG1741	Belongs to the pirin family
H2783_05235	COG2964	Protein conserved in bacteria
H2783_05250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2783_05255	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H2783_05260	COG4605	iron ion homeostasis
H2783_05265	COG4604	ABC transporter, ATP-binding protein
H2783_05270	COG4607	ABC-type enterochelin transport system periplasmic component
H2783_05275	COG4774	siderophore transport
H2783_05285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2783_05290	COG1021	2,3-dihydroxybenzoate-AMP ligase
H2783_05295	COG1535	isochorismatase
H2783_05295	COG3433	isochorismatase activity
H2783_05310	COG1132	(ABC) transporter
H2783_05315	COG1132	(ABC) transporter
H2783_05320	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H2783_05330	COG1169	isochorismate synthase
H2783_05345	COG3739	integral membrane protein
H2783_05365	COG0302	gtp cyclohydrolase
H2783_05375	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H2783_05405	COG0308	aminopeptidase N
H2783_05410	COG0512	Glutamine amidotransferase of anthranilate synthase
H2783_05425	COG0174	glutamine synthetase
H2783_05435	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H2783_05470	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H2783_05475	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H2783_05480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H2783_05500	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H2783_05505	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H2783_05510	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H2783_05525	COG1960	acyl-CoA dehydrogenase activity
H2783_05530	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H2783_05535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H2783_05545	COG2223	nitrite transmembrane transporter activity
H2783_05555	COG0024	Methionine aminopeptidase
H2783_05560	COG0052	Belongs to the universal ribosomal protein uS2 family
H2783_05575	COG2207	Transcriptional regulator
H2783_05600	COG2951	lytic endotransglycosylase activity
H2783_05605	COG0772	Belongs to the SEDS family
H2783_05620	COG0842	Transport permease protein
H2783_05625	COG1131	(ABC) transporter
H2783_05670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H2783_05685	COG4215	(ABC) transporter
H2783_05690	COG4160	amino acid transport
H2783_05695	COG4598	ABC transporter
H2783_05705	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H2783_05710	COG0826	peptidase U32
H2783_05715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H2783_05730	COG1720	tRNA m6t6A37 methyltransferase activity
H2783_05740	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H2783_05755	COG0642	Histidine kinase
H2783_05765	COG0494	nUDIX hydrolase
H2783_05775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H2783_05780	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H2783_05785	COG3139	Protein of unknown function (DUF1315)
H2783_05790	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H2783_05795	COG1301	dicarboxylic acid transport
H2783_05800	COG1960	acyl-CoA dehydrogenase activity
H2783_05805	COG2819	hydrolase of the alpha beta superfamily
H2783_05815	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H2783_05825	COG2195	Cleaves the N-terminal amino acid of tripeptides
H2783_05830	COG1234	tRNA 3'-trailer cleavage
H2783_05860	COG2363	Small membrane protein
H2783_05880	COG0513	Belongs to the DEAD box helicase family
H2783_05890	COG0778	Nitroreductase
H2783_05920	COG1286	toxin biosynthetic process
H2783_05945	COG4783	chaperone-mediated protein folding
H2783_05950	COG1610	YqeY-like protein
H2783_06050	COG3111	PFAM Bacterial OB fold (BOF) protein
H2783_06075	COG3243	poly(R)-hydroxyalkanoic acid synthase
H2783_06080	COG0786	glutamate:sodium symporter activity
H2783_06090	COG2186	Transcriptional regulator
H2783_06140	COG0477	Major facilitator Superfamily
H2783_06165	COG2985	domain, Protein
H2783_06175	COG2995	paraquat-inducible protein a
H2783_06180	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H2783_06180	COG3008	intermembrane lipid transfer
H2783_06190	COG1794	racemase activity, acting on amino acids and derivatives
H2783_06220	COG1301	dicarboxylic acid transport
H2783_06230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H2783_06235	COG2011	ABC-type metal ion transport system permease component
H2783_06240	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H2783_06245	COG1464	Belongs to the NlpA lipoprotein family
H2783_06250	COG0151	Belongs to the GarS family
H2783_06255	COG0138	bifunctional purine biosynthesis protein purh
H2783_06260	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H2783_06290	COG2308	Evidence 4 Homologs of previously reported genes of
H2783_06300	COG1305	Transglutaminase-like
H2783_06310	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H2783_06315	COG0305	Participates in initiation and elongation during chromosome replication
H2783_06340	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H2783_06350	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H2783_06355	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H2783_06380	COG1649	PFAM Uncharacterised BCR, COG1649
H2783_06380	COG0726	polysaccharide deacetylase
H2783_06385	COG1215	transferase activity, transferring glycosyl groups
H2783_06390	COG3658	cytochrome
H2783_06400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H2783_06415	COG0583	DNA-binding transcription factor activity
H2783_06435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H2783_06440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H2783_06455	COG1960	acyl-CoA dehydrogenase activity
H2783_06460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H2783_06465	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H2783_06490	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H2783_06495	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H2783_06505	COG2205	protein histidine kinase activity
H2783_06510	COG0745	RESPONSE REGULATOR receiver
H2783_06515	COG0174	glutamine synthetase
H2783_06535	COG0729	surface antigen
H2783_06560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H2783_06565	COG2814	Major facilitator Superfamily
H2783_06580	COG0583	DNA-binding transcription factor activity
H2783_06595	COG1187	pseudouridine synthase activity
H2783_06615	COG0802	atpase or kinase
H2783_06620	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H2783_06630	COG1923	regulation of RNA biosynthetic process
H2783_06635	COG0697	spore germination
H2783_06650	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H2783_06660	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H2783_06665	COG0519	Catalyzes the synthesis of GMP from XMP
H2783_06665	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H2783_06670	COG4302	ethanolamine ammonia-lyase activity
H2783_06675	COG4303	Ethanolamine ammonia lyase large subunit
H2783_06680	COG0531	amino acid
H2783_06700	COG1454	alcohol dehydrogenase
H2783_06705	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H2783_06715	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H2783_06735	COG0308	aminopeptidase N
H2783_06745	COG4221	oxidoreductase activity
H2783_06755	COG1605	Chorismate mutase
H2783_06770	COG1309	transcriptional regulator
H2783_06780	COG0668	transmembrane transport
H2783_06810	COG4773	Receptor
H2783_06830	COG0488	(ABC) transporter
H2783_06835	COG0589	response to stress
H2783_06860	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H2783_06870	COG3135	benzoate transporter
H2783_06875	COG1522	sequence-specific DNA binding
H2783_06885	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H2783_06890	COG0583	DNA-binding transcription factor activity
H2783_06900	COG0183	Belongs to the thiolase family
H2783_06910	COG2030	dehydratase
H2783_06915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H2783_06930	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H2783_06940	COG0824	Thioesterase
H2783_06945	COG1454	alcohol dehydrogenase
H2783_06955	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H2783_06975	COG0069	glutamate synthase activity
H2783_06995	COG2814	Major facilitator Superfamily
H2783_07010	COG0511	ligase activity, forming carbon-carbon bonds
H2783_07030	COG1116	anion transmembrane transporter activity
H2783_07030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H2783_07035	COG0745	RESPONSE REGULATOR receiver
H2783_07045	COG2146	nitrite reductase [NAD(P)H] activity
H2783_07045	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H2783_07050	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H2783_07055	COG0243	molybdopterin cofactor binding
H2783_07065	COG0243	molybdopterin cofactor binding
H2783_07070	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H2783_07085	COG0521	Mo-molybdopterin cofactor biosynthetic process
H2783_07085	COG0315	cyclic pyranopterin monophosphate synthase activity
H2783_07090	COG0303	'Molybdopterin
H2783_07100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H2783_07105	COG0697	spore germination
H2783_07125	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H2783_07130	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H2783_07185	COG2204	response regulator
H2783_07190	COG3852	Histidine kinase
H2783_07210	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H2783_07215	COG0575	Belongs to the CDS family
H2783_07250	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H2783_07265	COG2137	regulation of response to DNA damage stimulus
H2783_07275	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H2783_07280	COG1011	Hydrolase
H2783_07305	COG1522	sequence-specific DNA binding
H2783_07315	COG1113	amino acid transport
H2783_07330	COG0659	secondary active sulfate transmembrane transporter activity
H2783_07335	COG2135	peptidase activity
H2783_07350	COG5001	Diguanylate cyclase
H2783_07350	COG3300	MHYT domain
H2783_07370	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H2783_07370	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H2783_07370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H2783_07375	COG1105	Belongs to the carbohydrate kinase PfkB family
H2783_07380	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H2783_07380	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H2783_07410	COG0024	Methionine aminopeptidase
H2783_07415	COG0583	DNA-binding transcription factor activity
H2783_07425	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H2783_07430	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H2783_07435	COG0517	IMP dehydrogenase activity
H2783_07435	COG0516	GMP reductase activity
H2783_07460	COG0552	protein localization to endoplasmic reticulum
H2783_07470	COG4372	Transposase
H2783_07485	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
H2783_07500	COG4890	Cyd operon protein YbgT
H2783_07505	COG1294	oxidase, subunit
H2783_07525	COG1585	Membrane protein implicated in regulation of membrane protease activity
H2783_07535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H2783_07540	COG4774	siderophore transport
H2783_07555	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H2783_07560	COG0569	domain protein
H2783_07565	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H2783_07595	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H2783_07600	COG0542	response to heat
H2783_07625	COG1902	pentaerythritol trinitrate reductase activity
H2783_07625	COG0446	pyridine nucleotide-disulphide oxidoreductase
H2783_07670	COG2323	membrane
H2783_07675	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H2783_07685	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H2783_07690	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H2783_07695	COG0183	Belongs to the thiolase family
H2783_07700	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H2783_07705	COG0596	Alpha beta hydrolase
H2783_07710	COG2271	Major facilitator Superfamily
H2783_07715	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H2783_07720	COG3485	protocatechuate 3,4-dioxygenase
H2783_07725	COG3485	protocatechuate 3,4-dioxygenase
H2783_07730	COG0710	3-dehydroquinate dehydratase activity
H2783_07735	COG3420	alginic acid biosynthetic process
H2783_07740	COG3659	wide pore channel activity
H2783_07745	COG4993	Dehydrogenase
H2783_07755	COG2391	methyltransferase activity
H2783_07770	COG1414	Transcriptional regulator
H2783_07775	COG0583	DNA-binding transcription factor activity
H2783_07780	COG1960	acyl-CoA dehydrogenase activity
H2783_07805	COG2814	Major facilitator Superfamily
H2783_07815	COG0154	amidase activity
H2783_07835	COG4638	Rieske (2fe-2S)
H2783_07845	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_07855	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H2783_07865	COG3733	amine oxidase
H2783_07875	COG1012	belongs to the aldehyde dehydrogenase family
H2783_07885	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H2783_07890	COG0183	Belongs to the thiolase family
H2783_07895	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H2783_07900	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H2783_07910	COG4829	muconolactone delta-isomerase
H2783_07915	COG4948	Mandelate Racemase Muconate Lactonizing
H2783_07920	COG0583	DNA-binding transcription factor activity
H2783_07930	COG2186	Transcriptional regulator
H2783_07950	COG1012	belongs to the aldehyde dehydrogenase family
H2783_07970	COG1960	acyl-CoA dehydrogenase activity
H2783_07975	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_07980	COG3829	transcription factor binding
H2783_07990	COG3162	membrane
H2783_08005	COG1012	belongs to the aldehyde dehydrogenase family
H2783_08020	COG0753	catalase activity
H2783_08040	COG1846	Transcriptional regulator
H2783_08045	COG1902	pentaerythritol trinitrate reductase activity
H2783_08045	COG0446	pyridine nucleotide-disulphide oxidoreductase
H2783_08055	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H2783_08090	COG1309	transcriptional regulator
H2783_08100	COG1335	isochorismatase
H2783_08105	COG0583	DNA-binding transcription factor activity
H2783_08115	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H2783_08115	COG0475	glutathione-regulated potassium exporter activity
H2783_08125	COG1473	amidohydrolase
H2783_08135	COG2831	hemolysin activation secretion protein
H2783_08140	COG3210	domain, Protein
H2783_08170	COG2188	Transcriptional regulator
H2783_08185	COG0583	DNA-binding transcription factor activity
H2783_08215	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H2783_08235	COG1566	PFAM secretion protein HlyD family protein
H2783_08250	COG1012	belongs to the aldehyde dehydrogenase family
H2783_08255	COG0129	dihydroxy-acid dehydratase activity
H2783_08265	COG0583	DNA-binding transcription factor activity
H2783_08270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H2783_08280	COG2084	Dehydrogenase
H2783_08285	COG2207	Transcriptional regulator
H2783_08300	COG1064	alcohol dehydrogenase
H2783_08310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H2783_08315	COG1120	ATPase activity
H2783_08335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H2783_08450	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H2783_08500	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_08515	COG2207	Transcriptional regulator
H2783_08525	COG2205	protein histidine kinase activity
H2783_08530	COG0745	RESPONSE REGULATOR receiver
H2783_08535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H2783_08540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H2783_08545	COG1538	Outer membrane efflux protein
H2783_08555	COG2072	flavoprotein involved in K transport
H2783_08575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H2783_08595	COG3539	Fimbrial protein
H2783_08625	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H2783_08635	COG0753	catalase activity
H2783_08650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H2783_08715	COG1535	isochorismatase
H2783_08715	COG3433	isochorismatase activity
H2783_08720	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_08725	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H2783_08730	COG4149	molybdate abc transporter
H2783_08735	COG0725	ABC transporter, periplasmic molybdate-binding protein
H2783_08745	COG4638	Rieske (2fe-2S)
H2783_08750	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H2783_08755	COG0543	2 iron, 2 sulfur cluster binding
H2783_08755	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H2783_08780	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_08795	COG2207	Transcriptional regulator
H2783_08800	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_08805	COG2610	gluconate transmembrane transporter activity
H2783_08815	COG0583	DNA-binding transcription factor activity
H2783_08825	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H2783_08830	COG2031	fatty acid transporter
H2783_08835	COG0183	Belongs to the thiolase family
H2783_08840	COG0583	DNA-binding transcription factor activity
H2783_08845	COG0583	DNA-binding transcription factor activity
H2783_08860	COG1027	Aspartate ammonia-lyase
H2783_08870	COG0477	Major facilitator Superfamily
H2783_08890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H2783_08895	COG4521	taurine ABC transporter
H2783_08910	COG2188	Transcriptional regulator
H2783_08920	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H2783_08925	COG1733	regulation of RNA biosynthetic process
H2783_08930	COG2207	Transcriptional regulator
H2783_08930	COG3708	Transcriptional regulator
H2783_08945	COG0730	response to heat
H2783_08955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H2783_08955	COG3453	Protein conserved in bacteria
H2783_08965	COG3781	membrane
H2783_08970	COG1063	alcohol dehydrogenase
H2783_08980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H2783_08985	COG0508	dehydrogenase complex catalyzes the overall conversion of
H2783_08990	COG0022	dehydrogenase e1 component
H2783_08995	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H2783_09000	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H2783_09015	COG3706	GGDEF domain
H2783_09030	COG0133	tryptophan synthase activity
H2783_09040	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H2783_09075	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H2783_09100	COG2226	methyltransferase
H2783_09155	COG0842	Transport permease protein
H2783_09160	COG0842	Transport permease protein
H2783_09165	COG1131	(ABC) transporter
H2783_09180	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H2783_09185	COG4773	Receptor
H2783_09205	COG0730	response to heat
H2783_09210	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H2783_09230	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
H2783_09245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H2783_09285	COG4264	IucA IucC family
H2783_09290	COG4264	IucA IucC family
H2783_09310	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H2783_09325	COG1960	acyl-CoA dehydrogenase activity
H2783_09330	COG1960	acyl-CoA dehydrogenase activity
H2783_09335	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H2783_09340	COG2207	Transcriptional regulator
H2783_09345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H2783_09350	COG0776	regulation of translation
H2783_09375	COG0822	iron-sulfur transferase activity
H2783_09380	COG0316	Belongs to the HesB IscA family
H2783_09410	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H2783_09430	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H2783_09480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H2783_09490	COG0339	signal peptide processing
H2783_09540	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H2783_09545	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H2783_09575	COG0776	regulation of translation
H2783_09640	COG0084	hydrolase, TatD family'
H2783_09660	COG1663	tetraacyldisaccharide 4'-kinase activity
H2783_09665	COG1132	(ABC) transporter
H2783_09675	COG0811	peptide transport
H2783_09680	COG1475	DNA binding
H2783_09685	COG1192	Involved in chromosome partitioning
H2783_09695	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H2783_09710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H2783_09715	COG0191	fructose-bisphosphate aldolase activity
H2783_09735	COG0424	maF-like protein
H2783_09740	COG2850	peptidyl-arginine hydroxylation
H2783_09750	COG0640	Transcriptional regulator
H2783_09760	COG3619	membrane
H2783_09765	COG3122	Protein conserved in bacteria
H2783_09770	COG1132	(ABC) transporter
H2783_09790	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H2783_09795	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H2783_09805	COG0506	proline dehydrogenase activity
H2783_09805	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H2783_09805	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H2783_09810	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H2783_09825	COG3698	Phosphodiester glycosidase
H2783_09835	COG2353	YceI-like domain
H2783_09845	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H2783_09890	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H2783_09890	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H2783_09915	COG3539	Fimbrial protein
H2783_09920	COG3121	Chaperone
H2783_09945	COG0697	spore germination
H2783_09955	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H2783_09965	COG0583	DNA-binding transcription factor activity
H2783_09985	COG1309	transcriptional regulator
H2783_10000	COG1522	sequence-specific DNA binding
H2783_10010	COG1126	abc transporter atp-binding protein
H2783_10015	COG0765	amino acid transport
H2783_10020	COG0765	amino acid transport
H2783_10050	COG1464	Belongs to the NlpA lipoprotein family
H2783_10060	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H2783_10065	COG2011	ABC-type metal ion transport system permease component
H2783_10070	COG0012	GTP binding
H2783_10095	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H2783_10135	COG0386	Belongs to the glutathione peroxidase family
H2783_10145	COG0436	Aminotransferase
H2783_10185	COG3634	alkyl hydroperoxide reductase activity
H2783_10200	COG0583	DNA-binding transcription factor activity
H2783_10205	COG0798	PFAM Bile acid sodium symporter
H2783_10210	COG0640	Transcriptional regulator
H2783_10225	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H2783_10235	COG0583	DNA-binding transcription factor activity
H2783_10245	COG1953	Uracil, thiamine, allantoin
H2783_10255	COG2175	clavaminate synthase activity
H2783_10260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H2783_10265	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H2783_10270	COG4521	taurine ABC transporter
H2783_10280	COG0477	Major facilitator Superfamily
H2783_10300	COG1271	oxidase subunit
H2783_10305	COG1294	oxidase, subunit
H2783_10315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H2783_10335	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H2783_10355	COG3052	prosthetic group binding
H2783_10360	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
H2783_10370	COG2814	Major facilitator Superfamily
H2783_10390	COG1346	cytolysis
H2783_10400	COG0583	DNA-binding transcription factor activity
H2783_10405	COG0625	glutathione transferase activity
H2783_10410	COG0625	glutathione transferase activity
H2783_10415	COG0583	DNA-binding transcription factor activity
H2783_10430	COG1045	serine acetyltransferase
H2783_10435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H2783_10440	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H2783_10450	COG1280	lysine exporter protein (LysE YggA)
H2783_10465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H2783_10470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H2783_10475	COG1126	abc transporter atp-binding protein
H2783_10480	COG0765	amino acid transport
H2783_10485	COG0765	amino acid transport
H2783_10505	COG2205	protein histidine kinase activity
H2783_10505	COG0784	Response regulator, receiver
H2783_10525	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H2783_10545	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_10595	COG0583	DNA-binding transcription factor activity
H2783_10615	COG0318	PFAM AMP-dependent synthetase and ligase
H2783_10620	COG1309	transcriptional regulator
H2783_10625	COG1960	acyl-CoA dehydrogenase activity
H2783_10630	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H2783_10635	COG1024	Enoyl-CoA hydratase
H2783_10640	COG4770	biotin carboxylase activity
H2783_10650	COG0583	DNA-binding transcription factor activity
H2783_10665	COG1960	acyl-CoA dehydrogenase activity
H2783_10675	COG2814	Major facilitator Superfamily
H2783_10685	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H2783_10690	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H2783_10695	COG2814	Major facilitator Superfamily
H2783_10700	COG1960	acyl-CoA dehydrogenase activity
H2783_10705	COG1024	Enoyl-CoA hydratase
H2783_10710	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_10715	COG1250	3-hydroxyacyl-CoA dehydrogenase
H2783_10720	COG0183	Belongs to the thiolase family
H2783_10730	COG2814	Major facilitator Superfamily
H2783_10740	COG1024	Enoyl-CoA hydratase
H2783_10755	COG1960	acyl-CoA dehydrogenase activity
H2783_10760	COG2814	Major facilitator Superfamily
H2783_10765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H2783_10770	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H2783_10785	COG3842	ATPase activity
H2783_10790	COG1840	ABC-type Fe3 transport system, periplasmic component
H2783_10800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H2783_10805	COG1414	Transcriptional regulator
H2783_10815	COG0583	DNA-binding transcription factor activity
H2783_10820	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H2783_10825	COG1012	belongs to the aldehyde dehydrogenase family
H2783_10835	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H2783_10845	COG1012	belongs to the aldehyde dehydrogenase family
H2783_10850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H2783_10855	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H2783_10860	COG2267	carboxylic ester hydrolase activity
H2783_10880	COG3038	cytochrome b561
H2783_10885	COG0753	catalase activity
H2783_10920	COG2050	protein possibly involved in aromatic compounds catabolism
H2783_10930	COG3327	negative regulation of DNA-templated transcription, initiation
H2783_10935	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
H2783_10940	COG0183	Belongs to the thiolase family
H2783_10945	COG1250	3-hydroxyacyl-CoA dehydrogenase
H2783_10950	COG1024	Enoyl-CoA hydratase
H2783_10955	COG1024	Enoyl-CoA hydratase
H2783_10960	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H2783_10965	COG2151	metal-sulfur cluster biosynthetic enzyme
H2783_10970	COG3396	Phenylacetate-CoA oxygenase
H2783_10975	COG3460	Phenylacetate-CoA oxygenase
H2783_10980	COG3396	Phenylacetate-CoA oxygenase
H2783_10985	COG2030	dehydratase
H2783_10985	COG1012	belongs to the aldehyde dehydrogenase family
H2783_10990	COG1760	l-serine dehydratase
H2783_10995	COG0531	amino acid
H2783_11000	COG1012	belongs to the aldehyde dehydrogenase family
H2783_11015	COG0446	pyridine nucleotide-disulphide oxidoreductase
H2783_11025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H2783_11045	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H2783_11055	COG0789	Transcriptional regulator
H2783_11065	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H2783_11080	COG2807	transmembrane transport
H2783_11085	COG0590	tRNA wobble adenosine to inosine editing
H2783_11200	COG1116	anion transmembrane transporter activity
H2783_11205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H2783_11215	COG0864	Transcriptional regulator
H2783_11235	COG2249	NAD(P)H dehydrogenase (quinone) activity
H2783_11240	COG0439	Biotin carboxylase
H2783_11255	COG1063	alcohol dehydrogenase
H2783_11265	COG1309	transcriptional regulator
H2783_11285	COG0038	chloride channel
H2783_11290	COG4770	biotin carboxylase activity
H2783_11310	COG1914	H( )-stimulated, divalent metal cation uptake system
H2783_11315	COG0583	DNA-binding transcription factor activity
H2783_11360	COG4372	Transposase
H2783_11385	COG1250	3-hydroxyacyl-CoA dehydrogenase
H2783_11405	COG2814	Major facilitator Superfamily
H2783_11415	COG1560	Kdo2-lipid A biosynthetic process
H2783_11425	COG5006	permease, DMT superfamily
H2783_11430	COG1522	sequence-specific DNA binding
H2783_11445	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H2783_11455	COG4122	O-methyltransferase activity
H2783_11485	COG1538	Outer membrane efflux protein
H2783_11490	COG1137	ATPase activity
H2783_11495	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H2783_11505	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H2783_11510	COG0517	IMP dehydrogenase activity
H2783_11510	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H2783_11545	COG2814	Major facilitator Superfamily
H2783_11580	COG1278	Cold shock
H2783_11585	COG1280	lysine exporter protein (LysE YggA)
H2783_11615	COG1570	exodeoxyribonuclease VII activity
H2783_11670	COG0583	DNA-binding transcription factor activity
H2783_11675	COG4638	Rieske (2fe-2S)
H2783_11680	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H2783_11685	COG0543	2 iron, 2 sulfur cluster binding
H2783_11685	COG0633	Ferredoxin
H2783_11690	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_11695	COG3135	benzoate transporter
H2783_11700	COG2814	Major facilitator Superfamily
H2783_11715	COG1643	Atp-dependent helicase
H2783_11720	COG0450	alkyl hydroperoxide reductase
H2783_11730	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H2783_11740	COG3634	alkyl hydroperoxide reductase activity
H2783_11760	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H2783_11765	COG0625	glutathione transferase activity
H2783_11775	COG2885	chlorophyll binding
H2783_11810	COG0542	response to heat
H2783_11825	COG1765	OsmC-like protein
H2783_11840	COG0667	Aldo Keto reductase
H2783_11855	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H2783_11865	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H2783_11875	COG0527	aspartate kinase activity
H2783_11885	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H2783_11895	COG3038	cytochrome b561
H2783_11900	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H2783_11905	COG2252	PERMEase
H2783_11915	COG2072	flavoprotein involved in K transport
H2783_11930	COG1741	Belongs to the pirin family
H2783_11935	COG1309	transcriptional regulator
H2783_11945	COG0300	oxidoreductase activity
H2783_11960	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H2783_11990	COG1113	amino acid transport
H2783_12010	COG1012	belongs to the aldehyde dehydrogenase family
H2783_12030	COG0531	amino acid
H2783_12040	COG1113	amino acid transport
H2783_12080	COG3209	COG3209 Rhs family protein
H2783_12110	COG4269	membrane
H2783_12125	COG1902	pentaerythritol trinitrate reductase activity
H2783_12125	COG0446	pyridine nucleotide-disulphide oxidoreductase
H2783_12135	COG2203	Gaf domain
H2783_12135	COG3706	GGDEF domain
H2783_12135	COG4251	negative regulation of phosphorylation
H2783_12135	COG5001	Diguanylate cyclase
H2783_12145	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H2783_12165	COG4172	Belongs to the ABC transporter superfamily
H2783_12170	COG4239	(ABC) transporter, permease
H2783_12175	COG4174	ABC transporter (Permease)
H2783_12185	COG1388	LysM domain
H2783_12185	COG0741	lytic transglycosylase activity
H2783_12185	COG1388	LysM domain
H2783_12185	COG0741	lytic transglycosylase activity
H2783_12190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H2783_12230	COG0583	DNA-binding transcription factor activity
H2783_12235	COG1279	arginine transmembrane transporter activity
H2783_12255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H2783_12260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H2783_12265	COG0006	proline dipeptidase activity
H2783_12305	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H2783_12335	COG3384	dioxygenase
H2783_12345	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H2783_12350	COG2878	Part of a membrane complex involved in electron transport
H2783_12355	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H2783_12380	COG0768	penicillin binding
H2783_12385	COG0742	ribosomal rna small subunit methyltransferase
H2783_12400	COG0830	nickel cation binding
H2783_12410	COG0804	urea catabolic process
H2783_12450	COG1253	flavin adenine dinucleotide binding
H2783_12455	COG2851	Citrate transporter
H2783_12505	COG1773	rubredoxin
H2783_12510	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H2783_12520	COG0583	DNA-binding transcription factor activity
H2783_12545	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H2783_12550	COG4181	ATPase activity
H2783_12595	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H2783_12615	COG0306	phosphate transporter
H2783_12625	COG3958	Transketolase
H2783_12630	COG3959	Transketolase, thiamine diphosphate binding domain
H2783_12635	COG2271	Major facilitator Superfamily
H2783_12640	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_12645	COG0583	DNA-binding transcription factor activity
H2783_12660	COG2223	nitrite transmembrane transporter activity
H2783_12665	COG2207	Transcriptional regulator
H2783_12670	COG2066	Belongs to the glutaminase family
H2783_12675	COG0242	peptide deformylase activity
H2783_12680	COG0477	Major facilitator Superfamily
H2783_12690	COG0028	Belongs to the TPP enzyme family
H2783_12705	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_12710	COG2267	carboxylic ester hydrolase activity
H2783_12720	COG2271	Major facilitator Superfamily
H2783_12725	COG0446	pyridine nucleotide-disulphide oxidoreductase
H2783_12735	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_12755	COG1414	Transcriptional regulator
H2783_12770	COG1024	Enoyl-CoA hydratase
H2783_12780	COG1215	transferase activity, transferring glycosyl groups
H2783_12785	COG0726	polysaccharide deacetylase
H2783_12785	COG1649	PFAM Uncharacterised BCR, COG1649
H2783_12795	COG4681	YaeQ
H2783_12805	COG0523	cobalamin synthesis protein
H2783_12815	COG1607	acyl-coa hydrolase
H2783_12825	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H2783_12830	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H2783_12835	COG1309	transcriptional regulator
H2783_12860	COG2040	homocysteine
H2783_12865	COG0531	amino acid
H2783_12890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H2783_12895	COG0477	Major facilitator Superfamily
H2783_12950	COG0629	single-stranded DNA binding
H2783_12995	COG0582	viral genome integration into host DNA
H2783_13005	COG0405	Gamma-glutamyltransferase
H2783_13010	COG2814	Major facilitator Superfamily
H2783_13020	COG2050	protein possibly involved in aromatic compounds catabolism
H2783_13035	COG1090	epimerase
H2783_13055	COG0420	3'-5' exonuclease activity
H2783_13080	COG0735	belongs to the Fur family
H2783_13085	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H2783_13105	COG0121	glutamine amidotransferase
H2783_13120	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H2783_13130	COG0210	DNA helicase
H2783_13135	COG2885	chlorophyll binding
H2783_13140	COG0204	Acyl-transferase
H2783_13155	COG2894	cell division
H2783_13175	COG4372	Transposase
H2783_13200	COG1280	lysine exporter protein (LysE YggA)
H2783_13205	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H2783_13205	COG1674	ftsk spoiiie
H2783_13210	COG0492	ferredoxin-NADP+ reductase activity
H2783_13215	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H2783_13225	COG0456	acetyltransferase
H2783_13270	COG1981	membrane
H2783_13285	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H2783_13285	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H2783_13305	COG1012	belongs to the aldehyde dehydrogenase family
H2783_13315	COG0657	acetylesterase activity
H2783_13325	COG0473	3-isopropylmalate dehydrogenase activity
H2783_13330	COG0583	DNA-binding transcription factor activity
H2783_13350	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H2783_13375	COG0564	pseudouridine synthase activity
H2783_13385	COG0358	DNA primase activity
H2783_13400	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
H2783_13430	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H2783_13460	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H2783_13470	COG0352	thiamine-phosphate diphosphorylase activity
H2783_13470	COG0351	phosphomethylpyrimidine kinase
H2783_13470	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H2783_13475	COG1652	LysM domain
H2783_13500	COG1399	metal-binding, possibly nucleic acid-binding protein
H2783_13505	COG3101	peptidyl-lysine hydroxylation
H2783_13510	COG0009	L-threonylcarbamoyladenylate synthase
H2783_13515	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H2783_13520	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H2783_13535	COG4106	trans-aconitate 2-methyltransferase activity
H2783_13550	COG0596	Alpha beta hydrolase
H2783_13550	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H2783_13550	COG2226	methyltransferase
H2783_13555	COG1877	trehalose-phosphatase activity
H2783_13560	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H2783_13565	COG2223	nitrite transmembrane transporter activity
H2783_13585	COG1196	nuclear chromosome segregation
H2783_13595	COG0730	response to heat
H2783_13610	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H2783_13620	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H2783_13670	COG0489	protein tyrosine kinase activity
H2783_13680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H2783_13680	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H2783_13710	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H2783_13715	COG2081	HI0933 family
H2783_13725	COG0668	transmembrane transport
H2783_13745	COG0583	DNA-binding transcription factor activity
H2783_13765	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H2783_13770	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H2783_13800	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H2783_13840	COG0745	RESPONSE REGULATOR receiver
H2783_13860	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H2783_13870	COG2205	protein histidine kinase activity
H2783_13975	COG0384	phenazine biosynthesis protein PhzF
H2783_13995	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H2783_14010	COG0583	DNA-binding transcription factor activity
H2783_14040	COG0583	DNA-binding transcription factor activity
H2783_14055	COG0583	DNA-binding transcription factor activity
H2783_14060	COG1053	succinate dehydrogenase
H2783_14070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H2783_14075	COG2814	Major facilitator Superfamily
H2783_14080	COG1960	acyl-CoA dehydrogenase activity
H2783_14085	COG0583	DNA-binding transcription factor activity
H2783_14090	COG1063	alcohol dehydrogenase
H2783_14120	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H2783_14125	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H2783_14130	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H2783_14145	COG3667	copper resistance
H2783_14150	COG2132	Multicopper oxidase
H2783_14160	COG0561	phosphatase activity
H2783_14165	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H2783_14190	COG1214	PFAM Peptidase M22, glycoprotease
H2783_14240	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H2783_14250	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H2783_14255	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H2783_14260	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H2783_14320	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H2783_14330	COG1846	Transcriptional regulator
H2783_14335	COG1764	response to oxidative stress
H2783_14375	COG0037	tRNA processing
H2783_14385	COG0248	Ppx GppA phosphatase
H2783_14415	COG0072	phenylalanine-tRNA ligase activity
H2783_14455	COG1238	metal cluster binding
H2783_14460	COG0625	glutathione transferase activity
H2783_14475	COG0318	PFAM AMP-dependent synthetase and ligase
H2783_14480	COG3028	Belongs to the UPF0307 family
H2783_14485	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H2783_14505	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H2783_14510	COG0617	tRNA 3'-terminal CCA addition
H2783_14515	COG1555	photosystem II stabilization
H2783_14520	COG3956	TIGRFAM MazG family protein
H2783_14530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H2783_14550	COG0784	Response regulator, receiver
H2783_14550	COG2205	protein histidine kinase activity
H2783_14550	COG5002	protein histidine kinase activity
H2783_14555	COG1024	Enoyl-CoA hydratase
H2783_14560	COG2084	Dehydrogenase
H2783_14565	COG3622	Belongs to the hyi family
H2783_14595	COG0697	spore germination
H2783_14605	COG2814	Major facilitator Superfamily
H2783_14610	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H2783_14620	COG0583	DNA-binding transcription factor activity
H2783_14630	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H2783_14645	COG0084	hydrolase, TatD family'
H2783_14660	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H2783_14690	COG0440	acetolactate synthase activity
H2783_14695	COG0028	Belongs to the TPP enzyme family
H2783_14720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H2783_14725	COG0577	efflux transmembrane transporter activity
H2783_14725	COG1136	(ABC) transporter
H2783_14730	COG1538	Outer membrane efflux protein
H2783_14745	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H2783_14750	COG1162	GTPase activity
H2783_14760	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H2783_14780	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H2783_14785	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_14825	COG2986	histidine ammonia-lyase
H2783_14840	COG0318	PFAM AMP-dependent synthetase and ligase
H2783_14855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H2783_14900	COG1426	Protein conserved in bacteria
H2783_14935	COG0793	Belongs to the peptidase S41A family
H2783_14950	COG2267	carboxylic ester hydrolase activity
H2783_14960	COG1012	belongs to the aldehyde dehydrogenase family
H2783_14965	COG3265	gluconokinase activity
H2783_14975	COG0800	Aldolase
H2783_14985	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H2783_14990	COG0857	belongs to the CobB CobQ family
H2783_14990	COG0280	phosphate acetyltransferase
H2783_14995	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H2783_14995	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H2783_15015	COG0740	serine-type endopeptidase activity
H2783_15025	COG4774	siderophore transport
H2783_15035	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H2783_15045	COG2813	Specifically methylates the guanine in position
H2783_15045	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H2783_15145	COG0788	formyltetrahydrofolate deformylase activity
H2783_15170	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H2783_15170	COG4651	solute:proton antiporter activity
H2783_15190	COG0724	RNA recognition motif
H2783_15195	COG0210	DNA helicase
H2783_15220	COG1733	regulation of RNA biosynthetic process
H2783_15230	COG2900	Belongs to the SlyX family
H2783_15235	COG0488	(ABC) transporter
H2783_15240	COG1280	lysine exporter protein (LysE YggA)
H2783_15245	COG1560	Kdo2-lipid A biosynthetic process
H2783_15255	COG1301	dicarboxylic acid transport
H2783_15310	COG0473	3-isopropylmalate dehydrogenase activity
H2783_15375	COG0583	DNA-binding transcription factor activity
H2783_15385	COG0625	glutathione transferase activity
H2783_15390	COG2378	regulation of single-species biofilm formation
H2783_15395	COG0546	phosphoglycolate phosphatase activity
H2783_15405	COG1530	ribonuclease E activity
H2783_15410	COG0318	PFAM AMP-dependent synthetase and ligase
H2783_15425	COG0583	DNA-binding transcription factor activity
H2783_15430	COG4221	oxidoreductase activity
H2783_15435	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H2783_15445	COG0534	Mate efflux family protein
H2783_15460	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H2783_15500	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H2783_15505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H2783_15520	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H2783_15530	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H2783_15530	COG0644	oxidoreductase
H2783_15535	COG0425	Belongs to the sulfur carrier protein TusA family
H2783_15540	COG4535	Mg2 and Co2 transporter CorC
H2783_15550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H2783_15570	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H2783_15575	COG0475	glutathione-regulated potassium exporter activity
H2783_15575	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H2783_15580	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H2783_15590	COG0484	heat shock protein binding
H2783_15595	COG0789	Transcriptional regulator
H2783_15600	COG0598	Magnesium transport protein CorA
H2783_15615	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H2783_15620	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H2783_15625	COG1074	ATP-dependent DNA helicase activity
H2783_15630	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H2783_15650	COG2226	methyltransferase
H2783_15665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H2783_15670	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H2783_15685	COG2111	Na H antiporter
H2783_15685	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H2783_15690	COG1006	Multisubunit Na H antiporter MnhC subunit
H2783_15695	COG0651	ATP synthesis coupled electron transport
H2783_15700	COG1863	multisubunit Na H antiporter MnhE subunit
H2783_15705	COG2212	antiporter activity
H2783_15710	COG1320	monovalent cation:proton antiporter activity
H2783_15725	COG0195	Participates in both transcription termination and antitermination
H2783_15775	COG0237	dephospho-CoA kinase activity
H2783_15785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H2783_15800	COG0497	DNA recombination
H2783_15810	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H2783_15840	COG2169	Transcriptional regulator
H2783_15840	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H2783_15845	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H2783_15910	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H2783_15925	COG0326	Molecular chaperone. Has ATPase activity
H2783_15940	COG2056	Na+-H+ antiporter family
H2783_15945	COG0596	Alpha beta hydrolase
H2783_16040	COG0546	phosphoglycolate phosphatase activity
H2783_16045	COG1716	ATPase activity
H2783_16090	COG0181	hydroxymethylbilane synthase activity
H2783_16100	COG3275	phosphorelay sensor kinase activity
H2783_16120	COG1538	Outer membrane efflux protein
H2783_16125	COG0697	spore germination
H2783_16150	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H2783_16155	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H2783_16160	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H2783_16165	COG0772	Belongs to the SEDS family
H2783_16190	COG4974	Belongs to the 'phage' integrase family
H2783_16195	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H2783_16205	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H2783_16215	COG2197	response regulator
H2783_16230	COG0793	Belongs to the peptidase S41A family
H2783_16235	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H2783_16240	COG0795	lipopolysaccharide-transporting ATPase activity
H2783_16280	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H2783_16280	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H2783_16290	COG0004	ammonium transporteR
H2783_16295	COG0347	Belongs to the P(II) protein family
H2783_16305	COG0606	chelatase, subunit chli
H2783_16405	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H2783_16425	COG1061	Type III restriction enzyme res subunit
H2783_16465	COG0659	secondary active sulfate transmembrane transporter activity
H2783_16470	COG0589	response to stress
H2783_16495	COG4372	Transposase
H2783_16515	COG0606	chelatase, subunit chli
H2783_16520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H2783_16530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H2783_16545	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H2783_16560	COG0318	PFAM AMP-dependent synthetase and ligase
H2783_16570	COG0477	Major facilitator Superfamily
H2783_16575	COG2860	membrane
H2783_16585	COG1253	flavin adenine dinucleotide binding
H2783_16605	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H2783_16640	COG0655	NAD(P)H dehydrogenase (quinone) activity
H2783_16650	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H2783_16685	COG1309	transcriptional regulator
H2783_16720	COG0758	DNA mediated transformation
H2783_16730	COG0697	spore germination
H2783_16735	COG1309	transcriptional regulator
H2783_16760	COG0386	Belongs to the glutathione peroxidase family
H2783_16825	COG1121	(ABC) transporter
H2783_16830	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H2783_16835	COG1280	lysine exporter protein (LysE YggA)
H2783_16840	COG2837	iron assimilation
H2783_16850	COG0281	malic enzyme
H2783_16895	COG0519	Catalyzes the synthesis of GMP from XMP
H2783_16895	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H2783_16900	COG4399	Belongs to the UPF0754 family
H2783_16905	COG2259	Doxx family
H2783_16910	COG0586	Pfam SNARE associated Golgi protein
H2783_16925	COG1192	Involved in chromosome partitioning
H2783_16935	COG0271	Belongs to the BolA IbaG family
H2783_16955	COG2267	carboxylic ester hydrolase activity
H2783_16975	COG3321	synthase
H2783_16975	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H2783_16975	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H2783_16975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H2783_16980	COG1960	acyl-CoA dehydrogenase activity
H2783_16990	COG2197	response regulator
H2783_17000	COG3916	Acyl-homoserine-lactone synthase
H2783_17005	COG0477	Major facilitator Superfamily
H2783_17010	COG1024	Enoyl-CoA hydratase
H2783_17015	COG1024	Enoyl-CoA hydratase
H2783_17020	COG1960	acyl-CoA dehydrogenase activity
H2783_17025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H2783_17045	COG1113	amino acid transport
H2783_17050	COG1113	amino acid transport
H2783_17055	COG0251	oxidation-reduction process
H2783_17095	COG0564	pseudouridine synthase activity
H2783_17155	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H2783_17170	COG1802	Transcriptional regulator
H2783_17180	COG1448	Aminotransferase
H2783_17185	COG0277	FAD linked oxidase domain protein
H2783_17195	COG2186	Transcriptional regulator
H2783_17205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H2783_17210	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H2783_17225	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H2783_17230	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H2783_17235	COG1216	Glycosyl transferase, family 2
H2783_17265	COG2089	acid synthase
H2783_17280	COG1083	cytidylyl-transferase
H2783_17285	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H2783_17290	COG1086	Polysaccharide biosynthesis protein
H2783_17295	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H2783_17300	COG1596	polysaccharide export
H2783_17325	COG0728	peptidoglycan biosynthetic process
H2783_17330	COG3023	N-Acetylmuramoyl-L-alanine amidase
H2783_17385	COG0546	phosphoglycolate phosphatase activity
H2783_17390	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_17410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H2783_17415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H2783_17420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H2783_17425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H2783_17430	COG1116	anion transmembrane transporter activity
H2783_17435	COG1309	transcriptional regulator
H2783_17440	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H2783_17450	COG0196	riboflavin kinase activity
H2783_17455	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H2783_17465	COG1047	Peptidyl-prolyl cis-trans
H2783_17505	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H2783_17510	COG0657	acetylesterase activity
H2783_17560	COG2951	lytic endotransglycosylase activity
H2783_17565	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H2783_17580	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H2783_17590	COG0671	phosphoesterase, PA-phosphatase related
H2783_17595	COG0861	Integral membrane protein TerC family
H2783_17605	COG0754	glutathionylspermidine amidase activity
H2783_17615	COG0402	S-adenosylhomocysteine deaminase activity
H2783_17630	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H2783_17635	COG1230	cation diffusion facilitator family transporter
H2783_17650	COG0706	membrane insertase activity