locus-tag	class	description
L3Q73_00010	COG0592	DNA-directed DNA polymerase activity
L3Q73_00020	COG0187	DNA topoisomerase II activity
L3Q73_00030	COG0586	Pfam SNARE associated Golgi protein
L3Q73_00035	COG0488	(ABC) transporter
L3Q73_00060	COG0596	Alpha beta hydrolase
L3Q73_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
L3Q73_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L3Q73_00110	COG0733	neurotransmitter:sodium symporter activity
L3Q73_00150	COG2233	PERMEase
L3Q73_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L3Q73_00200	COG2814	Major facilitator Superfamily
L3Q73_00205	COG0656	L-ascorbic acid biosynthetic process
L3Q73_00210	COG0583	DNA-binding transcription factor activity
L3Q73_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L3Q73_00230	COG1064	alcohol dehydrogenase
L3Q73_00235	COG2818	Glycosylase
L3Q73_00250	COG1194	a g-specific adenine glycosylase
L3Q73_00270	COG2983	Belongs to the UPF0260 family
L3Q73_00275	COG2133	pyrroloquinoline quinone binding
L3Q73_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L3Q73_00285	COG2116	formate transmembrane transporter activity
L3Q73_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L3Q73_00310	COG1335	isochorismatase
L3Q73_00315	COG0385	Bile acid
L3Q73_00320	COG0534	Mate efflux family protein
L3Q73_00325	COG1683	Conserved Protein
L3Q73_00345	COG0625	glutathione transferase activity
L3Q73_00355	COG1113	amino acid transport
L3Q73_00365	COG0523	cobalamin synthesis protein
L3Q73_00375	COG2188	Transcriptional regulator
L3Q73_00405	COG0010	Belongs to the arginase family
L3Q73_00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L3Q73_00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L3Q73_00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L3Q73_00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
L3Q73_00555	COG0436	Aminotransferase
L3Q73_00560	COG2733	membrane
L3Q73_00575	COG2918	glutathione biosynthetic process
L3Q73_00590	COG0791	NLP P60 protein
L3Q73_00590	COG1388	LysM domain
L3Q73_00605	COG3150	esterase
L3Q73_00615	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q73_00620	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
L3Q73_00630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3Q73_00640	COG2233	PERMEase
L3Q73_00645	COG2351	hydroxyisourate hydrolase activity
L3Q73_00680	COG3706	GGDEF domain
L3Q73_00695	COG1393	Belongs to the ArsC family
L3Q73_00700	COG0708	Exodeoxyribonuclease III
L3Q73_00720	COG0189	ligase activity
L3Q73_00740	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L3Q73_00750	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L3Q73_00765	COG4942	peptidase
L3Q73_00775	COG0508	dehydrogenase complex catalyzes the overall conversion of
L3Q73_00785	COG2119	membrane
L3Q73_00790	COG4774	siderophore transport
L3Q73_00795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L3Q73_00795	COG0426	domain, Protein
L3Q73_00820	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L3Q73_00840	COG1902	pentaerythritol trinitrate reductase activity
L3Q73_00845	COG1519	Transferase
L3Q73_00850	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L3Q73_00855	COG0668	transmembrane transport
L3Q73_00865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L3Q73_00870	COG1335	isochorismatase
L3Q73_00875	COG1522	sequence-specific DNA binding
L3Q73_00880	COG3328	transposase activity
L3Q73_00905	COG2198	Histidine kinase
L3Q73_00905	COG2205	protein histidine kinase activity
L3Q73_00905	COG0784	Response regulator, receiver
L3Q73_00910	COG3162	membrane
L3Q73_00915	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L3Q73_00925	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L3Q73_00945	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L3Q73_00950	COG1309	transcriptional regulator
L3Q73_00970	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L3Q73_00970	COG0352	thiamine-phosphate diphosphorylase activity
L3Q73_00970	COG0351	phosphomethylpyrimidine kinase
L3Q73_00980	COG2814	Major facilitator Superfamily
L3Q73_00995	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L3Q73_01005	COG1113	amino acid transport
L3Q73_01015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L3Q73_01020	COG1012	belongs to the aldehyde dehydrogenase family
L3Q73_01030	COG1335	isochorismatase
L3Q73_01060	COG2814	Major facilitator Superfamily
L3Q73_01065	COG0583	DNA-binding transcription factor activity
L3Q73_01085	COG0667	Aldo Keto reductase
L3Q73_01120	COG1733	regulation of RNA biosynthetic process
L3Q73_01125	COG2249	NAD(P)H dehydrogenase (quinone) activity
L3Q73_01200	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L3Q73_01215	COG2329	Antibiotic biosynthesis monooxygenase
L3Q73_01245	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
L3Q73_01275	COG0427	acetyl-CoA hydrolase
L3Q73_01300	COG0659	secondary active sulfate transmembrane transporter activity
L3Q73_01305	COG4221	oxidoreductase activity
L3Q73_01310	COG2873	o-acetylhomoserine
L3Q73_01315	COG0488	(ABC) transporter
L3Q73_01400	COG0833	amino acid
L3Q73_01445	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
L3Q73_01450	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L3Q73_01465	COG2226	methyltransferase
L3Q73_01515	COG0069	glutamate synthase activity
L3Q73_01515	COG0067	glutamate synthase
L3Q73_01515	COG0070	glutamate synthase
L3Q73_01520	COG0493	'glutamate synthase
L3Q73_01530	COG1704	LemA family
L3Q73_01535	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
L3Q73_01555	COG3307	-O-antigen
L3Q73_01580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L3Q73_01595	COG0194	GDP metabolic process
L3Q73_01645	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
L3Q73_01665	COG5380	lipid catabolic process
L3Q73_01670	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
L3Q73_01695	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L3Q73_01700	COG0277	FAD linked oxidase domain protein
L3Q73_01710	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
L3Q73_01715	COG2249	NAD(P)H dehydrogenase (quinone) activity
L3Q73_01730	COG1289	transmembrane transporter activity
L3Q73_01740	COG0628	permease
L3Q73_01745	COG1192	Involved in chromosome partitioning
L3Q73_01775	COG0833	amino acid
L3Q73_01780	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L3Q73_01785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L3Q73_01795	COG1012	belongs to the aldehyde dehydrogenase family
L3Q73_01835	COG0583	DNA-binding transcription factor activity
L3Q73_01880	COG0517	IMP dehydrogenase activity
L3Q73_01885	COG1983	PspC domain protein
L3Q73_01895	COG1960	acyl-CoA dehydrogenase activity
L3Q73_01910	COG0408	coproporphyrinogen oxidase activity
L3Q73_01930	COG0513	Belongs to the DEAD box helicase family
L3Q73_01940	COG1127	ABC transporter
L3Q73_01945	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
L3Q73_01955	COG2854	intermembrane phospholipid transfer
L3Q73_01965	COG0598	Magnesium transport protein CorA
L3Q73_01975	COG0494	nUDIX hydrolase
L3Q73_01980	COG1040	competence protein
L3Q73_01985	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L3Q73_02005	COG1946	Acyl-CoA thioesterase
L3Q73_02010	COG1301	dicarboxylic acid transport
L3Q73_02025	COG1959	2 iron, 2 sulfur cluster binding
L3Q73_02030	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L3Q73_02030	COG1017	nitric oxide dioxygenase activity
L3Q73_02035	COG0433	COG0433 Predicted ATPase
L3Q73_02040	COG0626	cystathionine gamma-synthase activity
L3Q73_02195	COG1960	acyl-CoA dehydrogenase activity
L3Q73_02200	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
L3Q73_02230	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
L3Q73_02235	COG0339	signal peptide processing
L3Q73_02240	COG0557	exoribonuclease II activity
L3Q73_02285	COG0179	Fumarylacetoacetate (FAA) hydrolase
L3Q73_02290	COG2169	Transcriptional regulator
L3Q73_02295	COG0697	spore germination
L3Q73_02300	COG1295	ribonuclease BN
L3Q73_02335	COG1702	phosphate starvation-inducible protein PhoH
L3Q73_02345	COG1196	nuclear chromosome segregation
L3Q73_02345	COG0741	lytic transglycosylase activity
L3Q73_02345	COG0739	heme binding
L3Q73_02375	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
L3Q73_02380	COG1183	phosphatidylcholine synthase activity
L3Q73_02425	COG1960	acyl-CoA dehydrogenase activity
L3Q73_02430	COG1309	transcriptional regulator
L3Q73_02445	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L3Q73_02450	COG1960	acyl-CoA dehydrogenase activity
L3Q73_02470	COG2969	positive regulation of protein catabolic process
L3Q73_02480	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
L3Q73_02495	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
L3Q73_02500	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L3Q73_02520	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L3Q73_02530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L3Q73_02535	COG1408	metallophosphoesterase
L3Q73_02545	COG2199	diguanylate cyclase activity
L3Q73_02605	COG1607	acyl-coa hydrolase
L3Q73_02635	COG2350	Protein conserved in bacteria
L3Q73_02645	COG0613	PHP domain protein
L3Q73_02650	COG3781	membrane
L3Q73_02660	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L3Q73_02665	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L3Q73_02675	COG1862	Preprotein translocase
L3Q73_02705	COG2205	protein histidine kinase activity
L3Q73_02710	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
L3Q73_02730	COG0726	polysaccharide deacetylase
L3Q73_02735	COG0463	Glycosyl transferase, family 2
L3Q73_02740	COG0438	transferase activity, transferring glycosyl groups
L3Q73_02805	COG0625	glutathione transferase activity
L3Q73_02810	COG0583	DNA-binding transcription factor activity
L3Q73_02815	COG1960	acyl-CoA dehydrogenase activity
L3Q73_02820	COG1960	acyl-CoA dehydrogenase activity
L3Q73_02830	COG2205	protein histidine kinase activity
L3Q73_02835	COG0745	RESPONSE REGULATOR receiver
L3Q73_02840	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
L3Q73_02860	COG2096	Adenosyltransferase
L3Q73_02910	COG0285	dihydrofolate synthase activity
L3Q73_02930	COG0450	alkyl hydroperoxide reductase
L3Q73_02945	COG0477	Major facilitator Superfamily
L3Q73_02950	COG1272	protein, Hemolysin III
L3Q73_02980	COG0183	Belongs to the thiolase family
L3Q73_02985	COG2207	Transcriptional regulator
L3Q73_03005	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L3Q73_03025	COG0183	Belongs to the thiolase family
L3Q73_03035	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
L3Q73_03035	COG2885	chlorophyll binding
L3Q73_03045	COG1690	Belongs to the RtcB family
L3Q73_03050	COG0833	amino acid
L3Q73_03060	COG2233	PERMEase
L3Q73_03065	COG1217	gtp-binding protein TYPA
L3Q73_03090	COG2094	Belongs to the DNA glycosylase MPG family
L3Q73_03110	COG1902	pentaerythritol trinitrate reductase activity
L3Q73_03125	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L3Q73_03130	COG0354	folic acid binding
L3Q73_03140	COG3189	MarR family transcriptional regulator
L3Q73_03145	COG2824	Alkylphosphonate utilization operon protein PhnA
L3Q73_03150	COG3422	double-strand break repair
L3Q73_03190	COG0840	transmembrane signaling receptor activity
L3Q73_03210	COG5510	response to toxic substance
L3Q73_03220	COG2832	Protein of unknown function (DUF454)
L3Q73_03225	COG1376	ErfK ybiS ycfS ynhG family protein
L3Q73_03265	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
L3Q73_03275	COG1289	transmembrane transporter activity
L3Q73_03280	COG2814	Major facilitator Superfamily
L3Q73_03300	COG1115	amino acid carrier protein
L3Q73_03305	COG1752	Esterase of the alpha-beta hydrolase superfamily
L3Q73_03310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L3Q73_03315	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
L3Q73_03345	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L3Q73_03355	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L3Q73_03360	COG1077	Cell shape determining protein MreB Mrl
L3Q73_03365	COG1792	Involved in formation and maintenance of cell shape
L3Q73_03370	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
L3Q73_03375	COG0424	maF-like protein
L3Q73_03380	COG1530	ribonuclease E activity
L3Q73_03390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3Q73_03400	COG0560	Phosphoserine phosphatase
L3Q73_03410	COG2249	NAD(P)H dehydrogenase (quinone) activity
L3Q73_03435	COG2207	Transcriptional regulator
L3Q73_03455	COG1113	amino acid transport
L3Q73_03460	COG2828	Protein conserved in bacteria
L3Q73_03465	COG0142	geranyltranstransferase activity
L3Q73_03470	COG2315	Protein conserved in bacteria
L3Q73_03485	COG1752	Esterase of the alpha-beta hydrolase superfamily
L3Q73_03505	COG2194	sulfuric ester hydrolase activity
L3Q73_03510	COG0745	RESPONSE REGULATOR receiver
L3Q73_03515	COG0642	Histidine kinase
L3Q73_03525	COG0004	ammonium transporteR
L3Q73_03530	COG0583	DNA-binding transcription factor activity
L3Q73_03550	COG0525	valine-tRNA ligase activity
L3Q73_03560	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q73_03570	COG0393	Putative heavy-metal-binding
L3Q73_03575	COG0393	Putative heavy-metal-binding
L3Q73_03580	COG1538	Outer membrane efflux protein
L3Q73_03590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L3Q73_03595	COG0671	phosphoesterase, PA-phosphatase related
L3Q73_03625	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L3Q73_03640	COG1648	precorrin-2 dehydrogenase activity
L3Q73_03640	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L3Q73_03645	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L3Q73_03650	COG1733	regulation of RNA biosynthetic process
L3Q73_03660	COG0531	amino acid
L3Q73_03675	COG0321	lipoyl(octanoyl) transferase activity
L3Q73_03680	COG2921	Belongs to the UPF0250 family
L3Q73_03720	COG2009	succinate dehydrogenase
L3Q73_03725	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
L3Q73_03730	COG1053	succinate dehydrogenase
L3Q73_03735	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L3Q73_03760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L3Q73_03780	COG2354	Protein conserved in bacteria
L3Q73_03785	COG2321	neutral zinc metallopeptidase
L3Q73_03805	COG2843	Capsule synthesis protein
L3Q73_03820	COG0589	response to stress
L3Q73_03840	COG0505	Belongs to the CarA family
L3Q73_03865	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L3Q73_03870	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L3Q73_03920	COG0477	Major facilitator Superfamily
L3Q73_03925	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
L3Q73_03940	COG1597	lipid kinase activity
L3Q73_03945	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L3Q73_03975	COG0584	glycerophosphoryl diester phosphodiesterase
L3Q73_03995	COG0741	lytic transglycosylase activity
L3Q73_04015	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
L3Q73_04030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3Q73_04060	COG0778	Nitroreductase
L3Q73_04075	COG1929	Belongs to the glycerate kinase type-1 family
L3Q73_04080	COG0243	molybdopterin cofactor binding
L3Q73_04085	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L3Q73_04090	COG3339	Conserved Protein
L3Q73_04100	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
L3Q73_04115	COG1113	amino acid transport
L3Q73_04125	COG0019	diaminopimelate decarboxylase activity
L3Q73_04135	COG1280	lysine exporter protein (LysE YggA)
L3Q73_04140	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L3Q73_04170	COG0463	Glycosyl transferase, family 2
L3Q73_04190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L3Q73_04225	COG4591	ABC-type transport system involved in lipoprotein release permease component
L3Q73_04230	COG1136	(ABC) transporter
L3Q73_04235	COG0658	competence protein
L3Q73_04235	COG2333	competence protein COMEC
L3Q73_04245	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L3Q73_04245	COG0616	signal peptide processing
L3Q73_04250	COG0596	Alpha beta hydrolase
L3Q73_04255	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L3Q73_04265	COG0628	permease
L3Q73_04300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L3Q73_04320	COG0823	Involved in the tonB-independent uptake of proteins
L3Q73_04340	COG0824	Thioesterase
L3Q73_04345	COG1473	amidohydrolase
L3Q73_04365	COG0047	phosphoribosylformylglycinamidine synthase activity
L3Q73_04365	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L3Q73_04370	COG2814	Major facilitator Superfamily
L3Q73_04380	COG1024	Enoyl-CoA hydratase
L3Q73_04385	COG1051	belongs to the nudix hydrolase family
L3Q73_04385	COG1056	cytidyltransferase-related domain
L3Q73_04395	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L3Q73_04410	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
L3Q73_04425	COG4625	pathogenesis
L3Q73_04430	COG0583	DNA-binding transcription factor activity
L3Q73_04435	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
L3Q73_04440	COG4208	sulfate ABC transporter
L3Q73_04445	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
L3Q73_04455	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
L3Q73_04460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L3Q73_04465	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L3Q73_04485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L3Q73_04500	COG0681	Belongs to the peptidase S26 family
L3Q73_04515	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L3Q73_04525	COG1381	Involved in DNA repair and RecF pathway recombination
L3Q73_04530	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
L3Q73_04540	COG4221	oxidoreductase activity
L3Q73_04570	COG0436	Aminotransferase
L3Q73_04590	COG0556	nucleotide-excision repair
L3Q73_04645	COG2070	2-Nitropropane dioxygenase
L3Q73_04675	COG1215	transferase activity, transferring glycosyl groups
L3Q73_04690	COG0415	Belongs to the DNA photolyase family
L3Q73_04700	COG1252	NADH dehydrogenase
L3Q73_04705	COG1686	Belongs to the peptidase S11 family
L3Q73_04720	COG1187	pseudouridine synthase activity
L3Q73_04745	COG0477	Major facilitator Superfamily
L3Q73_04750	COG0583	DNA-binding transcription factor activity
L3Q73_04755	COG1823	symporter activity
L3Q73_04765	COG0612	Peptidase, M16
L3Q73_04790	COG0352	thiamine-phosphate diphosphorylase activity
L3Q73_04825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L3Q73_04840	COG1309	transcriptional regulator
L3Q73_04850	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L3Q73_04855	COG0076	glutamate decarboxylase activity
L3Q73_04865	COG1522	sequence-specific DNA binding
L3Q73_04870	COG3961	Belongs to the TPP enzyme family
L3Q73_04875	COG1113	amino acid transport
L3Q73_04880	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L3Q73_04885	COG0573	inorganic phosphate transmembrane transporter activity
L3Q73_04895	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L3Q73_04900	COG0616	signal peptide processing
L3Q73_04935	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L3Q73_04940	COG1686	Belongs to the peptidase S11 family
L3Q73_04965	COG0583	DNA-binding transcription factor activity
L3Q73_04970	COG1067	ATP-dependent peptidase activity
L3Q73_05015	COG1966	Carbon starvation protein
L3Q73_05020	COG2879	small protein
L3Q73_05055	COG2508	Transcriptional regulator
L3Q73_05055	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
L3Q73_05075	COG1113	amino acid transport
L3Q73_05080	COG0583	DNA-binding transcription factor activity
L3Q73_05085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L3Q73_05090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L3Q73_05100	COG1012	belongs to the aldehyde dehydrogenase family
L3Q73_05110	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L3Q73_05115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L3Q73_05115	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
L3Q73_05150	COG2814	Major facilitator Superfamily
L3Q73_05155	COG4948	Mandelate Racemase Muconate Lactonizing
L3Q73_05165	COG1309	transcriptional regulator
L3Q73_05185	COG1741	Belongs to the pirin family
L3Q73_05195	COG2964	Protein conserved in bacteria
L3Q73_05210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3Q73_05215	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L3Q73_05220	COG4605	iron ion homeostasis
L3Q73_05225	COG4604	ABC transporter, ATP-binding protein
L3Q73_05230	COG4607	ABC-type enterochelin transport system periplasmic component
L3Q73_05235	COG4774	siderophore transport
L3Q73_05245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3Q73_05250	COG1021	2,3-dihydroxybenzoate-AMP ligase
L3Q73_05255	COG3433	isochorismatase activity
L3Q73_05255	COG1535	isochorismatase
L3Q73_05270	COG1132	(ABC) transporter
L3Q73_05275	COG1132	(ABC) transporter
L3Q73_05280	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
L3Q73_05290	COG1169	isochorismate synthase
L3Q73_05305	COG3739	integral membrane protein
L3Q73_05330	COG0302	gtp cyclohydrolase
L3Q73_05340	COG1529	Aldehyde oxidase and xanthine dehydrogenase
L3Q73_05370	COG0308	aminopeptidase N
L3Q73_05375	COG0512	Glutamine amidotransferase of anthranilate synthase
L3Q73_05390	COG0174	glutamine synthetase
L3Q73_05400	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
L3Q73_05435	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L3Q73_05440	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L3Q73_05445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L3Q73_05465	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L3Q73_05470	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L3Q73_05475	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
L3Q73_05490	COG1960	acyl-CoA dehydrogenase activity
L3Q73_05495	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L3Q73_05500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L3Q73_05510	COG2223	nitrite transmembrane transporter activity
L3Q73_05520	COG0024	Methionine aminopeptidase
L3Q73_05525	COG0052	Belongs to the universal ribosomal protein uS2 family
L3Q73_05540	COG2207	Transcriptional regulator
L3Q73_05565	COG2951	lytic endotransglycosylase activity
L3Q73_05570	COG0772	Belongs to the SEDS family
L3Q73_05585	COG0842	Transport permease protein
L3Q73_05590	COG1131	(ABC) transporter
L3Q73_05635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L3Q73_05650	COG4215	(ABC) transporter
L3Q73_05655	COG4160	amino acid transport
L3Q73_05660	COG4598	ABC transporter
L3Q73_05670	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L3Q73_05675	COG0826	peptidase U32
L3Q73_05680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L3Q73_05695	COG1720	tRNA m6t6A37 methyltransferase activity
L3Q73_05705	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L3Q73_05720	COG0642	Histidine kinase
L3Q73_05730	COG0494	nUDIX hydrolase
L3Q73_05740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L3Q73_05745	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
L3Q73_05750	COG3139	Protein of unknown function (DUF1315)
L3Q73_05755	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L3Q73_05760	COG1301	dicarboxylic acid transport
L3Q73_05765	COG1960	acyl-CoA dehydrogenase activity
L3Q73_05770	COG2819	hydrolase of the alpha beta superfamily
L3Q73_05780	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
L3Q73_05790	COG2195	Cleaves the N-terminal amino acid of tripeptides
L3Q73_05795	COG1234	tRNA 3'-trailer cleavage
L3Q73_05825	COG2363	Small membrane protein
L3Q73_05850	COG0513	Belongs to the DEAD box helicase family
L3Q73_05860	COG0778	Nitroreductase
L3Q73_06210	COG1286	toxin biosynthetic process
L3Q73_06235	COG4783	chaperone-mediated protein folding
L3Q73_06240	COG1610	YqeY-like protein
L3Q73_06340	COG3111	PFAM Bacterial OB fold (BOF) protein
L3Q73_06365	COG3243	poly(R)-hydroxyalkanoic acid synthase
L3Q73_06370	COG0786	glutamate:sodium symporter activity
L3Q73_06380	COG2186	Transcriptional regulator
L3Q73_06430	COG0477	Major facilitator Superfamily
L3Q73_06460	COG2985	domain, Protein
L3Q73_06470	COG2995	paraquat-inducible protein a
L3Q73_06475	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
L3Q73_06475	COG3008	intermembrane lipid transfer
L3Q73_06500	COG1301	dicarboxylic acid transport
L3Q73_06510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L3Q73_06515	COG2011	ABC-type metal ion transport system permease component
L3Q73_06520	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L3Q73_06525	COG1464	Belongs to the NlpA lipoprotein family
L3Q73_06530	COG0151	Belongs to the GarS family
L3Q73_06535	COG0138	bifunctional purine biosynthesis protein purh
L3Q73_06540	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
L3Q73_06570	COG2308	Evidence 4 Homologs of previously reported genes of
L3Q73_06580	COG1305	Transglutaminase-like
L3Q73_06590	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L3Q73_06595	COG0305	Participates in initiation and elongation during chromosome replication
L3Q73_06620	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
L3Q73_06630	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L3Q73_06635	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L3Q73_06660	COG0726	polysaccharide deacetylase
L3Q73_06660	COG1649	PFAM Uncharacterised BCR, COG1649
L3Q73_06665	COG1215	transferase activity, transferring glycosyl groups
L3Q73_06670	COG3658	cytochrome
L3Q73_06680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q73_06695	COG0583	DNA-binding transcription factor activity
L3Q73_06715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L3Q73_06720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L3Q73_06735	COG1960	acyl-CoA dehydrogenase activity
L3Q73_06740	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L3Q73_06745	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L3Q73_06770	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
L3Q73_06775	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
L3Q73_06785	COG2205	protein histidine kinase activity
L3Q73_06790	COG0745	RESPONSE REGULATOR receiver
L3Q73_06795	COG0174	glutamine synthetase
L3Q73_06815	COG0729	surface antigen
L3Q73_06840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L3Q73_06845	COG2814	Major facilitator Superfamily
L3Q73_06860	COG0583	DNA-binding transcription factor activity
L3Q73_06875	COG1187	pseudouridine synthase activity
L3Q73_06895	COG0802	atpase or kinase
L3Q73_06900	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
L3Q73_06910	COG1923	regulation of RNA biosynthetic process
L3Q73_06915	COG0697	spore germination
L3Q73_06930	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L3Q73_06940	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L3Q73_06945	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L3Q73_06945	COG0519	Catalyzes the synthesis of GMP from XMP
L3Q73_06950	COG4302	ethanolamine ammonia-lyase activity
L3Q73_06955	COG4303	Ethanolamine ammonia lyase large subunit
L3Q73_06960	COG0531	amino acid
L3Q73_06980	COG1454	alcohol dehydrogenase
L3Q73_06985	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L3Q73_06995	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
L3Q73_07015	COG0308	aminopeptidase N
L3Q73_07025	COG4221	oxidoreductase activity
L3Q73_07035	COG1605	Chorismate mutase
L3Q73_07055	COG1309	transcriptional regulator
L3Q73_07065	COG0668	transmembrane transport
L3Q73_07100	COG4773	Receptor
L3Q73_07120	COG0488	(ABC) transporter
L3Q73_07125	COG0589	response to stress
L3Q73_07150	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L3Q73_07160	COG3135	benzoate transporter
L3Q73_07165	COG1522	sequence-specific DNA binding
L3Q73_07175	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
L3Q73_07180	COG0583	DNA-binding transcription factor activity
L3Q73_07190	COG0183	Belongs to the thiolase family
L3Q73_07200	COG2030	dehydratase
L3Q73_07205	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L3Q73_07220	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L3Q73_07230	COG0824	Thioesterase
L3Q73_07235	COG1454	alcohol dehydrogenase
L3Q73_07245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L3Q73_07265	COG0069	glutamate synthase activity
L3Q73_07425	COG5410	chromosome segregation
L3Q73_07565	COG0739	heme binding
L3Q73_07565	COG0741	lytic transglycosylase activity
L3Q73_07565	COG1196	nuclear chromosome segregation
L3Q73_07635	COG2814	Major facilitator Superfamily
L3Q73_07650	COG0511	ligase activity, forming carbon-carbon bonds
L3Q73_07670	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L3Q73_07670	COG1116	anion transmembrane transporter activity
L3Q73_07675	COG0745	RESPONSE REGULATOR receiver
L3Q73_07685	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L3Q73_07685	COG2146	nitrite reductase [NAD(P)H] activity
L3Q73_07690	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L3Q73_07695	COG0243	molybdopterin cofactor binding
L3Q73_07705	COG0243	molybdopterin cofactor binding
L3Q73_07710	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L3Q73_07725	COG0315	cyclic pyranopterin monophosphate synthase activity
L3Q73_07725	COG0521	Mo-molybdopterin cofactor biosynthetic process
L3Q73_07730	COG0303	'Molybdopterin
L3Q73_07740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L3Q73_07745	COG0697	spore germination
L3Q73_07765	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
L3Q73_07770	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L3Q73_07835	COG2204	response regulator
L3Q73_07840	COG3852	Histidine kinase
L3Q73_07860	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L3Q73_07865	COG0575	Belongs to the CDS family
L3Q73_07900	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L3Q73_07915	COG2137	regulation of response to DNA damage stimulus
L3Q73_07925	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L3Q73_07930	COG1011	Hydrolase
L3Q73_07955	COG1522	sequence-specific DNA binding
L3Q73_07965	COG1113	amino acid transport
L3Q73_07985	COG0659	secondary active sulfate transmembrane transporter activity
L3Q73_07990	COG2135	peptidase activity
L3Q73_08005	COG5001	Diguanylate cyclase
L3Q73_08005	COG3300	MHYT domain
L3Q73_08025	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L3Q73_08025	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
L3Q73_08025	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L3Q73_08030	COG1105	Belongs to the carbohydrate kinase PfkB family
L3Q73_08035	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L3Q73_08035	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
L3Q73_08065	COG0024	Methionine aminopeptidase
L3Q73_08070	COG0583	DNA-binding transcription factor activity
L3Q73_08080	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
L3Q73_08085	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L3Q73_08090	COG0516	GMP reductase activity
L3Q73_08090	COG0517	IMP dehydrogenase activity
L3Q73_08115	COG0552	protein localization to endoplasmic reticulum
L3Q73_08125	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
L3Q73_08140	COG4890	Cyd operon protein YbgT
L3Q73_08145	COG1294	oxidase, subunit
L3Q73_08160	COG1585	Membrane protein implicated in regulation of membrane protease activity
L3Q73_08170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L3Q73_08175	COG4774	siderophore transport
L3Q73_08190	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L3Q73_08195	COG0569	domain protein
L3Q73_08200	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L3Q73_08230	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
L3Q73_08235	COG0542	response to heat
L3Q73_08260	COG0446	pyridine nucleotide-disulphide oxidoreductase
L3Q73_08260	COG1902	pentaerythritol trinitrate reductase activity
L3Q73_08305	COG2323	membrane
L3Q73_08310	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
L3Q73_08320	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L3Q73_08325	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L3Q73_08330	COG0183	Belongs to the thiolase family
L3Q73_08335	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L3Q73_08340	COG0596	Alpha beta hydrolase
L3Q73_08345	COG2271	Major facilitator Superfamily
L3Q73_08350	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L3Q73_08355	COG3485	protocatechuate 3,4-dioxygenase
L3Q73_08360	COG3485	protocatechuate 3,4-dioxygenase
L3Q73_08365	COG0710	3-dehydroquinate dehydratase activity
L3Q73_08370	COG3420	alginic acid biosynthetic process
L3Q73_08375	COG3659	wide pore channel activity
L3Q73_08380	COG4993	Dehydrogenase
L3Q73_08390	COG2391	methyltransferase activity
L3Q73_08405	COG1414	Transcriptional regulator
L3Q73_08410	COG0583	DNA-binding transcription factor activity
L3Q73_08415	COG1960	acyl-CoA dehydrogenase activity
L3Q73_08440	COG2814	Major facilitator Superfamily
L3Q73_08450	COG0154	amidase activity
L3Q73_08470	COG4638	Rieske (2fe-2S)
L3Q73_08480	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q73_08490	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L3Q73_08500	COG3733	amine oxidase
L3Q73_08510	COG1012	belongs to the aldehyde dehydrogenase family
L3Q73_08520	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L3Q73_08525	COG0183	Belongs to the thiolase family
L3Q73_08530	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L3Q73_08535	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L3Q73_08545	COG4829	muconolactone delta-isomerase
L3Q73_08550	COG4948	Mandelate Racemase Muconate Lactonizing
L3Q73_08555	COG0583	DNA-binding transcription factor activity
L3Q73_08565	COG2186	Transcriptional regulator
L3Q73_08585	COG1012	belongs to the aldehyde dehydrogenase family
L3Q73_08605	COG1960	acyl-CoA dehydrogenase activity
L3Q73_08610	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q73_08615	COG3829	transcription factor binding
L3Q73_08625	COG3162	membrane
L3Q73_08640	COG1012	belongs to the aldehyde dehydrogenase family
L3Q73_08655	COG0753	catalase activity
L3Q73_08675	COG1846	Transcriptional regulator
L3Q73_08680	COG0446	pyridine nucleotide-disulphide oxidoreductase
L3Q73_08680	COG1902	pentaerythritol trinitrate reductase activity
L3Q73_08690	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L3Q73_08720	COG1309	transcriptional regulator
L3Q73_08730	COG1335	isochorismatase
L3Q73_08735	COG0583	DNA-binding transcription factor activity
L3Q73_08745	COG0475	glutathione-regulated potassium exporter activity
L3Q73_08745	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L3Q73_08755	COG1473	amidohydrolase
L3Q73_08765	COG2831	hemolysin activation secretion protein
L3Q73_08770	COG3210	domain, Protein
L3Q73_08800	COG2188	Transcriptional regulator
L3Q73_08815	COG0583	DNA-binding transcription factor activity
L3Q73_08845	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L3Q73_08875	COG1566	PFAM secretion protein HlyD family protein
L3Q73_08890	COG1012	belongs to the aldehyde dehydrogenase family
L3Q73_08895	COG0129	dihydroxy-acid dehydratase activity
L3Q73_08905	COG0583	DNA-binding transcription factor activity
L3Q73_08910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L3Q73_08920	COG2084	Dehydrogenase
L3Q73_08925	COG2207	Transcriptional regulator
L3Q73_08940	COG1064	alcohol dehydrogenase
L3Q73_08950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L3Q73_08955	COG1120	ATPase activity
L3Q73_08975	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L3Q73_09095	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
L3Q73_09130	COG3328	transposase activity
L3Q73_09150	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q73_09165	COG2207	Transcriptional regulator
L3Q73_09175	COG2205	protein histidine kinase activity
L3Q73_09180	COG0745	RESPONSE REGULATOR receiver
L3Q73_09190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L3Q73_09195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L3Q73_09200	COG1538	Outer membrane efflux protein
L3Q73_09210	COG2072	flavoprotein involved in K transport
L3Q73_09230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L3Q73_09250	COG3539	Fimbrial protein
L3Q73_09280	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
L3Q73_09290	COG0753	catalase activity
L3Q73_09305	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L3Q73_09365	COG3433	isochorismatase activity
L3Q73_09365	COG1535	isochorismatase
L3Q73_09370	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q73_09375	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
L3Q73_09380	COG4149	molybdate abc transporter
L3Q73_09385	COG0725	ABC transporter, periplasmic molybdate-binding protein
L3Q73_09395	COG4638	Rieske (2fe-2S)
L3Q73_09400	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L3Q73_09405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L3Q73_09405	COG0543	2 iron, 2 sulfur cluster binding
L3Q73_09430	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q73_09445	COG2207	Transcriptional regulator
L3Q73_09455	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q73_09460	COG2610	gluconate transmembrane transporter activity
L3Q73_09470	COG0583	DNA-binding transcription factor activity
L3Q73_09480	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L3Q73_09485	COG2031	fatty acid transporter
L3Q73_09490	COG0183	Belongs to the thiolase family
L3Q73_09495	COG0583	DNA-binding transcription factor activity
L3Q73_09500	COG0583	DNA-binding transcription factor activity
L3Q73_09515	COG1027	Aspartate ammonia-lyase
L3Q73_09525	COG0477	Major facilitator Superfamily
L3Q73_09545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L3Q73_09550	COG4521	taurine ABC transporter
L3Q73_09565	COG2188	Transcriptional regulator
L3Q73_09575	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
L3Q73_09580	COG1733	regulation of RNA biosynthetic process
L3Q73_09585	COG2207	Transcriptional regulator
L3Q73_09585	COG3708	Transcriptional regulator
L3Q73_09600	COG0730	response to heat
L3Q73_09615	COG3453	Protein conserved in bacteria
L3Q73_09615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L3Q73_09625	COG3781	membrane
L3Q73_09630	COG1063	alcohol dehydrogenase
L3Q73_09640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L3Q73_09645	COG0508	dehydrogenase complex catalyzes the overall conversion of
L3Q73_09650	COG0022	dehydrogenase e1 component
L3Q73_09655	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L3Q73_09660	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L3Q73_09675	COG3706	GGDEF domain
L3Q73_09690	COG0133	tryptophan synthase activity
L3Q73_09700	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L3Q73_09735	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
L3Q73_09760	COG2226	methyltransferase
L3Q73_09815	COG0842	Transport permease protein
L3Q73_09820	COG0842	Transport permease protein
L3Q73_09825	COG1131	(ABC) transporter
L3Q73_09840	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L3Q73_09845	COG4773	Receptor
L3Q73_09865	COG0730	response to heat
L3Q73_09870	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L3Q73_09890	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
L3Q73_09905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L3Q73_09945	COG4264	IucA IucC family
L3Q73_09950	COG4264	IucA IucC family
L3Q73_09970	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L3Q73_09985	COG1960	acyl-CoA dehydrogenase activity
L3Q73_09990	COG1960	acyl-CoA dehydrogenase activity
L3Q73_09995	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L3Q73_10000	COG2207	Transcriptional regulator
L3Q73_10005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L3Q73_10010	COG0776	regulation of translation
L3Q73_10035	COG0822	iron-sulfur transferase activity
L3Q73_10040	COG0316	Belongs to the HesB IscA family
L3Q73_10070	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L3Q73_10090	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L3Q73_10095	COG0702	epimerase
L3Q73_10150	COG0339	signal peptide processing
L3Q73_10200	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L3Q73_10260	COG1196	nuclear chromosome segregation
L3Q73_10260	COG0741	lytic transglycosylase activity
L3Q73_10260	COG0739	heme binding
L3Q73_10320	COG4695	Portal protein
L3Q73_10410	COG0305	Participates in initiation and elongation during chromosome replication
L3Q73_10475	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
L3Q73_10505	COG0776	regulation of translation
L3Q73_10570	COG0084	hydrolase, TatD family'
L3Q73_10590	COG1663	tetraacyldisaccharide 4'-kinase activity
L3Q73_10595	COG1132	(ABC) transporter
L3Q73_10605	COG0811	peptide transport
L3Q73_10610	COG1475	DNA binding
L3Q73_10615	COG1192	Involved in chromosome partitioning
L3Q73_10625	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L3Q73_10640	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L3Q73_10645	COG0191	fructose-bisphosphate aldolase activity
L3Q73_10665	COG0424	maF-like protein
L3Q73_10670	COG2850	peptidyl-arginine hydroxylation
L3Q73_10680	COG0640	Transcriptional regulator
L3Q73_10690	COG3619	membrane
L3Q73_10695	COG3122	Protein conserved in bacteria
L3Q73_10700	COG1132	(ABC) transporter
L3Q73_10720	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
L3Q73_10725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L3Q73_10735	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L3Q73_10735	COG0506	proline dehydrogenase activity
L3Q73_10735	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L3Q73_10740	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L3Q73_10755	COG3698	Phosphodiester glycosidase
L3Q73_10765	COG2353	YceI-like domain
L3Q73_10775	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L3Q73_10820	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
L3Q73_10820	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
L3Q73_10845	COG3539	Fimbrial protein
L3Q73_10850	COG3121	Chaperone
L3Q73_10875	COG0697	spore germination
L3Q73_10885	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L3Q73_10895	COG0583	DNA-binding transcription factor activity
L3Q73_10915	COG1309	transcriptional regulator
L3Q73_10930	COG1522	sequence-specific DNA binding
L3Q73_10945	COG1126	abc transporter atp-binding protein
L3Q73_10950	COG0765	amino acid transport
L3Q73_10955	COG0765	amino acid transport
L3Q73_10985	COG1464	Belongs to the NlpA lipoprotein family
L3Q73_10995	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L3Q73_11000	COG2011	ABC-type metal ion transport system permease component
L3Q73_11005	COG0012	GTP binding
L3Q73_11030	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L3Q73_11070	COG0386	Belongs to the glutathione peroxidase family
L3Q73_11080	COG0436	Aminotransferase
L3Q73_11120	COG3634	alkyl hydroperoxide reductase activity
L3Q73_11135	COG0583	DNA-binding transcription factor activity
L3Q73_11140	COG0798	PFAM Bile acid sodium symporter
L3Q73_11145	COG0640	Transcriptional regulator
L3Q73_11160	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
L3Q73_11170	COG0583	DNA-binding transcription factor activity
L3Q73_11180	COG1953	Uracil, thiamine, allantoin
L3Q73_11190	COG2175	clavaminate synthase activity
L3Q73_11195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L3Q73_11200	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
L3Q73_11205	COG4521	taurine ABC transporter
L3Q73_11215	COG0477	Major facilitator Superfamily
L3Q73_11240	COG1271	oxidase subunit
L3Q73_11245	COG1294	oxidase, subunit
L3Q73_11255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L3Q73_11275	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L3Q73_11295	COG3052	prosthetic group binding
L3Q73_11300	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
L3Q73_11310	COG2814	Major facilitator Superfamily
L3Q73_11330	COG1346	cytolysis
L3Q73_11340	COG0583	DNA-binding transcription factor activity
L3Q73_11345	COG0625	glutathione transferase activity
L3Q73_11350	COG0625	glutathione transferase activity
L3Q73_11355	COG0583	DNA-binding transcription factor activity
L3Q73_11370	COG1045	serine acetyltransferase
L3Q73_11375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L3Q73_11380	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L3Q73_11390	COG1280	lysine exporter protein (LysE YggA)
L3Q73_11405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L3Q73_11410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L3Q73_11415	COG1126	abc transporter atp-binding protein
L3Q73_11420	COG0765	amino acid transport
L3Q73_11425	COG0765	amino acid transport
L3Q73_11445	COG2205	protein histidine kinase activity
L3Q73_11445	COG0784	Response regulator, receiver
L3Q73_11465	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L3Q73_11485	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q73_11535	COG0583	DNA-binding transcription factor activity
L3Q73_11555	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q73_11560	COG1309	transcriptional regulator
L3Q73_11565	COG1960	acyl-CoA dehydrogenase activity
L3Q73_11570	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L3Q73_11575	COG1024	Enoyl-CoA hydratase
L3Q73_11580	COG4770	biotin carboxylase activity
L3Q73_11590	COG0583	DNA-binding transcription factor activity
L3Q73_11605	COG1960	acyl-CoA dehydrogenase activity
L3Q73_11615	COG2814	Major facilitator Superfamily
L3Q73_11625	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L3Q73_11630	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L3Q73_11635	COG2814	Major facilitator Superfamily
L3Q73_11640	COG1960	acyl-CoA dehydrogenase activity
L3Q73_11645	COG1024	Enoyl-CoA hydratase
L3Q73_11655	COG1250	3-hydroxyacyl-CoA dehydrogenase
L3Q73_11660	COG0183	Belongs to the thiolase family
L3Q73_11670	COG2814	Major facilitator Superfamily
L3Q73_11680	COG1024	Enoyl-CoA hydratase
L3Q73_11695	COG1960	acyl-CoA dehydrogenase activity
L3Q73_11700	COG2814	Major facilitator Superfamily
L3Q73_11705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L3Q73_11710	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L3Q73_11725	COG3842	ATPase activity
L3Q73_11730	COG1840	ABC-type Fe3 transport system, periplasmic component
L3Q73_11740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3Q73_11745	COG1414	Transcriptional regulator
L3Q73_11755	COG0583	DNA-binding transcription factor activity
L3Q73_11760	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L3Q73_11765	COG1012	belongs to the aldehyde dehydrogenase family
L3Q73_11775	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L3Q73_11785	COG1012	belongs to the aldehyde dehydrogenase family
L3Q73_11790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q73_11795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L3Q73_11800	COG2267	carboxylic ester hydrolase activity
L3Q73_11820	COG3038	cytochrome b561
L3Q73_11825	COG0753	catalase activity
L3Q73_11860	COG2050	protein possibly involved in aromatic compounds catabolism
L3Q73_11870	COG3327	negative regulation of DNA-templated transcription, initiation
L3Q73_11875	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
L3Q73_11880	COG0183	Belongs to the thiolase family
L3Q73_11885	COG1250	3-hydroxyacyl-CoA dehydrogenase
L3Q73_11890	COG1024	Enoyl-CoA hydratase
L3Q73_11895	COG1024	Enoyl-CoA hydratase
L3Q73_11900	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L3Q73_11905	COG2151	metal-sulfur cluster biosynthetic enzyme
L3Q73_11910	COG3396	Phenylacetate-CoA oxygenase
L3Q73_11915	COG3460	Phenylacetate-CoA oxygenase
L3Q73_11920	COG3396	Phenylacetate-CoA oxygenase
L3Q73_11925	COG1012	belongs to the aldehyde dehydrogenase family
L3Q73_11925	COG2030	dehydratase
L3Q73_11930	COG1760	l-serine dehydratase
L3Q73_11935	COG0531	amino acid
L3Q73_11940	COG1012	belongs to the aldehyde dehydrogenase family
L3Q73_11955	COG0446	pyridine nucleotide-disulphide oxidoreductase
L3Q73_11965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L3Q73_11985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L3Q73_11995	COG0789	Transcriptional regulator
L3Q73_12010	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
L3Q73_12025	COG2807	transmembrane transport
L3Q73_12030	COG0590	tRNA wobble adenosine to inosine editing
L3Q73_12160	COG1116	anion transmembrane transporter activity
L3Q73_12165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L3Q73_12175	COG0864	Transcriptional regulator
L3Q73_12195	COG2249	NAD(P)H dehydrogenase (quinone) activity
L3Q73_12200	COG0439	Biotin carboxylase
L3Q73_12215	COG1063	alcohol dehydrogenase
L3Q73_12225	COG1309	transcriptional regulator
L3Q73_12245	COG0038	chloride channel
L3Q73_12250	COG4770	biotin carboxylase activity
L3Q73_12270	COG1914	H( )-stimulated, divalent metal cation uptake system
L3Q73_12275	COG0583	DNA-binding transcription factor activity
L3Q73_12325	COG1250	3-hydroxyacyl-CoA dehydrogenase
L3Q73_12345	COG2814	Major facilitator Superfamily
L3Q73_12355	COG1560	Kdo2-lipid A biosynthetic process
L3Q73_12365	COG5006	permease, DMT superfamily
L3Q73_12370	COG1522	sequence-specific DNA binding
L3Q73_12385	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
L3Q73_12395	COG4122	O-methyltransferase activity
L3Q73_12425	COG1538	Outer membrane efflux protein
L3Q73_12430	COG1137	ATPase activity
L3Q73_12435	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
L3Q73_12445	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
L3Q73_12450	COG0517	IMP dehydrogenase activity
L3Q73_12450	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
L3Q73_12485	COG2814	Major facilitator Superfamily
L3Q73_12520	COG1278	Cold shock
L3Q73_12525	COG1280	lysine exporter protein (LysE YggA)
L3Q73_12605	COG0583	DNA-binding transcription factor activity
L3Q73_12615	COG4638	Rieske (2fe-2S)
L3Q73_12620	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L3Q73_12625	COG0633	Ferredoxin
L3Q73_12625	COG0543	2 iron, 2 sulfur cluster binding
L3Q73_12630	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q73_12635	COG3135	benzoate transporter
L3Q73_12640	COG2814	Major facilitator Superfamily
L3Q73_12655	COG1643	Atp-dependent helicase
L3Q73_12660	COG0450	alkyl hydroperoxide reductase
L3Q73_12670	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
L3Q73_12680	COG3634	alkyl hydroperoxide reductase activity
L3Q73_12700	COG0220	tRNA (guanine-N7-)-methyltransferase activity
L3Q73_12705	COG0625	glutathione transferase activity
L3Q73_12715	COG2885	chlorophyll binding
L3Q73_12750	COG0542	response to heat
L3Q73_12765	COG1765	OsmC-like protein
L3Q73_12785	COG0667	Aldo Keto reductase
L3Q73_12800	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
L3Q73_12810	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L3Q73_12820	COG0527	aspartate kinase activity
L3Q73_12830	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
L3Q73_12840	COG3038	cytochrome b561
L3Q73_12845	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
L3Q73_12935	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L3Q73_12985	COG1012	belongs to the aldehyde dehydrogenase family
L3Q73_13005	COG0531	amino acid
L3Q73_13015	COG1113	amino acid transport
L3Q73_13055	COG3209	COG3209 Rhs family protein
L3Q73_13085	COG4269	membrane
L3Q73_13100	COG0446	pyridine nucleotide-disulphide oxidoreductase
L3Q73_13100	COG1902	pentaerythritol trinitrate reductase activity
L3Q73_13110	COG4251	negative regulation of phosphorylation
L3Q73_13110	COG3706	GGDEF domain
L3Q73_13110	COG2203	Gaf domain
L3Q73_13110	COG5001	Diguanylate cyclase
L3Q73_13120	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L3Q73_13140	COG4172	Belongs to the ABC transporter superfamily
L3Q73_13145	COG4239	(ABC) transporter, permease
L3Q73_13150	COG4174	ABC transporter (Permease)
L3Q73_13160	COG0741	lytic transglycosylase activity
L3Q73_13160	COG1388	LysM domain
L3Q73_13160	COG0741	lytic transglycosylase activity
L3Q73_13160	COG1388	LysM domain
L3Q73_13165	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L3Q73_13205	COG0583	DNA-binding transcription factor activity
L3Q73_13210	COG1279	arginine transmembrane transporter activity
L3Q73_13230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3Q73_13235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3Q73_13240	COG0006	proline dipeptidase activity
L3Q73_13325	COG0741	lytic transglycosylase activity
L3Q73_13325	COG1196	nuclear chromosome segregation
L3Q73_13325	COG0739	heme binding
L3Q73_13385	COG4695	Portal protein
L3Q73_13485	COG0305	Participates in initiation and elongation during chromosome replication
L3Q73_13500	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L3Q73_13560	COG2194	sulfuric ester hydrolase activity
L3Q73_13605	COG0739	heme binding
L3Q73_13930	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L3Q73_13955	COG3384	dioxygenase
L3Q73_13965	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L3Q73_13970	COG2878	Part of a membrane complex involved in electron transport
L3Q73_13975	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L3Q73_14000	COG0768	penicillin binding
L3Q73_14005	COG0742	ribosomal rna small subunit methyltransferase
L3Q73_14020	COG0830	nickel cation binding
L3Q73_14030	COG0804	urea catabolic process
L3Q73_14070	COG1253	flavin adenine dinucleotide binding
L3Q73_14075	COG2851	Citrate transporter
L3Q73_14125	COG1773	rubredoxin
L3Q73_14130	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L3Q73_14140	COG0583	DNA-binding transcription factor activity
L3Q73_14165	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
L3Q73_14170	COG4181	ATPase activity
L3Q73_14215	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L3Q73_14235	COG0306	phosphate transporter
L3Q73_14245	COG3958	Transketolase
L3Q73_14250	COG3959	Transketolase, thiamine diphosphate binding domain
L3Q73_14255	COG2271	Major facilitator Superfamily
L3Q73_14260	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q73_14265	COG0583	DNA-binding transcription factor activity
L3Q73_14280	COG2223	nitrite transmembrane transporter activity
L3Q73_14285	COG2207	Transcriptional regulator
L3Q73_14290	COG2066	Belongs to the glutaminase family
L3Q73_14295	COG0242	peptide deformylase activity
L3Q73_14300	COG0477	Major facilitator Superfamily
L3Q73_14310	COG0028	Belongs to the TPP enzyme family
L3Q73_14325	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q73_14330	COG2267	carboxylic ester hydrolase activity
L3Q73_14340	COG2271	Major facilitator Superfamily
L3Q73_14345	COG0446	pyridine nucleotide-disulphide oxidoreductase
L3Q73_14355	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q73_14375	COG1414	Transcriptional regulator
L3Q73_14390	COG1024	Enoyl-CoA hydratase
L3Q73_14400	COG1215	transferase activity, transferring glycosyl groups
L3Q73_14405	COG0726	polysaccharide deacetylase
L3Q73_14405	COG1649	PFAM Uncharacterised BCR, COG1649
L3Q73_14415	COG4681	YaeQ
L3Q73_14425	COG0523	cobalamin synthesis protein
L3Q73_14435	COG1607	acyl-coa hydrolase
L3Q73_14445	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L3Q73_14450	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L3Q73_14455	COG1309	transcriptional regulator
L3Q73_14480	COG2040	homocysteine
L3Q73_14485	COG0531	amino acid
L3Q73_14540	COG1595	DNA-templated transcription, initiation
L3Q73_14550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L3Q73_14555	COG0477	Major facilitator Superfamily
L3Q73_14575	COG0084	hydrolase, TatD family'
L3Q73_14610	COG0629	single-stranded DNA binding
L3Q73_14665	COG0582	viral genome integration into host DNA
L3Q73_14695	COG1061	Type III restriction enzyme res subunit
L3Q73_14705	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L3Q73_14710	COG1192	Involved in chromosome partitioning
L3Q73_14720	COG1061	Type III restriction enzyme res subunit
L3Q73_14810	COG0592	DNA-directed DNA polymerase activity
L3Q73_14850	COG2026	Addiction module toxin, RelE StbE family
L3Q73_15000	COG3755	Protein conserved in bacteria
L3Q73_15045	COG1484	DNA-dependent DNA replication
L3Q73_15135	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L3Q73_15205	COG0405	Gamma-glutamyltransferase
L3Q73_15210	COG2814	Major facilitator Superfamily
L3Q73_15220	COG2050	protein possibly involved in aromatic compounds catabolism
L3Q73_15235	COG1090	epimerase
L3Q73_15255	COG0420	3'-5' exonuclease activity
L3Q73_15280	COG0735	belongs to the Fur family
L3Q73_15285	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L3Q73_15305	COG0121	glutamine amidotransferase
L3Q73_15320	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L3Q73_15330	COG0210	DNA helicase
L3Q73_15335	COG2885	chlorophyll binding
L3Q73_15340	COG0204	Acyl-transferase
L3Q73_15355	COG2894	cell division
L3Q73_15380	COG1280	lysine exporter protein (LysE YggA)
L3Q73_15385	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
L3Q73_15385	COG1674	ftsk spoiiie
L3Q73_15390	COG0492	ferredoxin-NADP+ reductase activity
L3Q73_15395	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
L3Q73_15405	COG0456	acetyltransferase
L3Q73_15450	COG1981	membrane
L3Q73_15465	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L3Q73_15465	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
L3Q73_15485	COG1012	belongs to the aldehyde dehydrogenase family
L3Q73_15495	COG0657	acetylesterase activity
L3Q73_15505	COG0473	3-isopropylmalate dehydrogenase activity
L3Q73_15510	COG0583	DNA-binding transcription factor activity
L3Q73_15530	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L3Q73_15555	COG0564	pseudouridine synthase activity
L3Q73_15565	COG0358	DNA primase activity
L3Q73_15580	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
L3Q73_15610	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L3Q73_15640	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L3Q73_15650	COG0352	thiamine-phosphate diphosphorylase activity
L3Q73_15650	COG0351	phosphomethylpyrimidine kinase
L3Q73_15650	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L3Q73_15655	COG1652	LysM domain
L3Q73_15680	COG1399	metal-binding, possibly nucleic acid-binding protein
L3Q73_15685	COG3101	peptidyl-lysine hydroxylation
L3Q73_15690	COG0009	L-threonylcarbamoyladenylate synthase
L3Q73_15695	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
L3Q73_15700	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
L3Q73_15715	COG4106	trans-aconitate 2-methyltransferase activity
L3Q73_15730	COG0596	Alpha beta hydrolase
L3Q73_15730	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L3Q73_15730	COG2226	methyltransferase
L3Q73_15735	COG1877	trehalose-phosphatase activity
L3Q73_15740	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
L3Q73_15745	COG2223	nitrite transmembrane transporter activity
L3Q73_15765	COG1196	nuclear chromosome segregation
L3Q73_15775	COG0730	response to heat
L3Q73_15790	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L3Q73_15800	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L3Q73_15850	COG0489	protein tyrosine kinase activity
L3Q73_15860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L3Q73_15860	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L3Q73_15890	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L3Q73_15895	COG2081	HI0933 family
L3Q73_15905	COG0668	transmembrane transport
L3Q73_15925	COG0583	DNA-binding transcription factor activity
L3Q73_15945	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L3Q73_15950	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L3Q73_15980	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
L3Q73_16020	COG0745	RESPONSE REGULATOR receiver
L3Q73_16040	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L3Q73_16050	COG2205	protein histidine kinase activity
L3Q73_16120	COG4993	Dehydrogenase
L3Q73_16145	COG0384	phenazine biosynthesis protein PhzF
L3Q73_16170	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L3Q73_16185	COG0583	DNA-binding transcription factor activity
L3Q73_16215	COG0583	DNA-binding transcription factor activity
L3Q73_16230	COG0583	DNA-binding transcription factor activity
L3Q73_16235	COG1053	succinate dehydrogenase
L3Q73_16245	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L3Q73_16250	COG2814	Major facilitator Superfamily
L3Q73_16255	COG1960	acyl-CoA dehydrogenase activity
L3Q73_16260	COG0583	DNA-binding transcription factor activity
L3Q73_16265	COG1063	alcohol dehydrogenase
L3Q73_16295	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
L3Q73_16300	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
L3Q73_16305	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L3Q73_16320	COG3667	copper resistance
L3Q73_16325	COG2132	Multicopper oxidase
L3Q73_16335	COG0561	phosphatase activity
L3Q73_16340	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L3Q73_16365	COG1214	PFAM Peptidase M22, glycoprotease
L3Q73_16415	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
L3Q73_16425	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
L3Q73_16430	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
L3Q73_16435	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L3Q73_16495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L3Q73_16505	COG1846	Transcriptional regulator
L3Q73_16510	COG1764	response to oxidative stress
L3Q73_16550	COG0037	tRNA processing
L3Q73_16560	COG0248	Ppx GppA phosphatase
L3Q73_16590	COG0072	phenylalanine-tRNA ligase activity
L3Q73_16635	COG1238	metal cluster binding
L3Q73_16640	COG0625	glutathione transferase activity
L3Q73_16655	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q73_16660	COG3028	Belongs to the UPF0307 family
L3Q73_16665	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L3Q73_16685	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L3Q73_16690	COG0617	tRNA 3'-terminal CCA addition
L3Q73_16695	COG1555	photosystem II stabilization
L3Q73_16700	COG3956	TIGRFAM MazG family protein
L3Q73_16710	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L3Q73_16730	COG0784	Response regulator, receiver
L3Q73_16730	COG2205	protein histidine kinase activity
L3Q73_16730	COG5002	protein histidine kinase activity
L3Q73_16735	COG1024	Enoyl-CoA hydratase
L3Q73_16740	COG2084	Dehydrogenase
L3Q73_16745	COG3622	Belongs to the hyi family
L3Q73_16775	COG0697	spore germination
L3Q73_16785	COG2814	Major facilitator Superfamily
L3Q73_16790	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L3Q73_16800	COG0583	DNA-binding transcription factor activity
L3Q73_16810	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L3Q73_16825	COG0084	hydrolase, TatD family'
L3Q73_16840	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
L3Q73_16870	COG0440	acetolactate synthase activity
L3Q73_16875	COG0028	Belongs to the TPP enzyme family
L3Q73_16900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L3Q73_16905	COG0577	efflux transmembrane transporter activity
L3Q73_16905	COG1136	(ABC) transporter
L3Q73_16910	COG1538	Outer membrane efflux protein
L3Q73_16925	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
L3Q73_16930	COG1162	GTPase activity
L3Q73_16940	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
L3Q73_16960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L3Q73_16965	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q73_17005	COG2986	histidine ammonia-lyase
L3Q73_17020	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q73_17030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L3Q73_17075	COG1426	Protein conserved in bacteria
L3Q73_17110	COG0793	Belongs to the peptidase S41A family
L3Q73_17125	COG2267	carboxylic ester hydrolase activity
L3Q73_17135	COG1012	belongs to the aldehyde dehydrogenase family
L3Q73_17140	COG3265	gluconokinase activity
L3Q73_17150	COG0800	Aldolase
L3Q73_17160	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L3Q73_17165	COG0857	belongs to the CobB CobQ family
L3Q73_17165	COG0280	phosphate acetyltransferase
L3Q73_17170	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
L3Q73_17170	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
L3Q73_17190	COG0740	serine-type endopeptidase activity
L3Q73_17200	COG4774	siderophore transport
L3Q73_17210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L3Q73_17220	COG2813	Specifically methylates the guanine in position
L3Q73_17220	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L3Q73_17320	COG0788	formyltetrahydrofolate deformylase activity
L3Q73_17345	COG4651	solute:proton antiporter activity
L3Q73_17345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L3Q73_17365	COG0724	RNA recognition motif
L3Q73_17370	COG0210	DNA helicase
L3Q73_17395	COG1733	regulation of RNA biosynthetic process
L3Q73_17405	COG2900	Belongs to the SlyX family
L3Q73_17410	COG0488	(ABC) transporter
L3Q73_17415	COG1280	lysine exporter protein (LysE YggA)
L3Q73_17420	COG1560	Kdo2-lipid A biosynthetic process
L3Q73_17430	COG1301	dicarboxylic acid transport
L3Q73_17485	COG0473	3-isopropylmalate dehydrogenase activity
L3Q73_17550	COG0583	DNA-binding transcription factor activity
L3Q73_17560	COG0625	glutathione transferase activity
L3Q73_17565	COG2378	regulation of single-species biofilm formation
L3Q73_17570	COG0546	phosphoglycolate phosphatase activity
L3Q73_17580	COG1530	ribonuclease E activity
L3Q73_17585	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q73_17600	COG0583	DNA-binding transcription factor activity
L3Q73_17605	COG4221	oxidoreductase activity
L3Q73_17610	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L3Q73_17620	COG0534	Mate efflux family protein
L3Q73_17635	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L3Q73_17685	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
L3Q73_17690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L3Q73_17705	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L3Q73_17715	COG0644	oxidoreductase
L3Q73_17715	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
L3Q73_17720	COG0425	Belongs to the sulfur carrier protein TusA family
L3Q73_17725	COG4535	Mg2 and Co2 transporter CorC
L3Q73_17735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L3Q73_17755	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L3Q73_17760	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L3Q73_17760	COG0475	glutathione-regulated potassium exporter activity
L3Q73_17765	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
L3Q73_17775	COG0484	heat shock protein binding
L3Q73_17780	COG0789	Transcriptional regulator
L3Q73_17785	COG0598	Magnesium transport protein CorA
L3Q73_17800	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L3Q73_17805	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L3Q73_17810	COG1074	ATP-dependent DNA helicase activity
L3Q73_17815	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
L3Q73_17835	COG2226	methyltransferase
L3Q73_17850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3Q73_17855	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
L3Q73_17870	COG2111	Na H antiporter
L3Q73_17870	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L3Q73_17875	COG1006	Multisubunit Na H antiporter MnhC subunit
L3Q73_17880	COG0651	ATP synthesis coupled electron transport
L3Q73_17885	COG1863	multisubunit Na H antiporter MnhE subunit
L3Q73_17890	COG2212	antiporter activity
L3Q73_17895	COG1320	monovalent cation:proton antiporter activity
L3Q73_17910	COG0195	Participates in both transcription termination and antitermination
L3Q73_17960	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
L3Q73_17965	COG0237	dephospho-CoA kinase activity
L3Q73_17975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L3Q73_17990	COG0497	DNA recombination
L3Q73_18000	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
L3Q73_18030	COG2169	Transcriptional regulator
L3Q73_18030	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L3Q73_18035	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L3Q73_18100	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L3Q73_18115	COG0326	Molecular chaperone. Has ATPase activity
L3Q73_18130	COG2056	Na+-H+ antiporter family
L3Q73_18135	COG0596	Alpha beta hydrolase
L3Q73_18230	COG0546	phosphoglycolate phosphatase activity
L3Q73_18235	COG1716	ATPase activity
L3Q73_18280	COG0181	hydroxymethylbilane synthase activity
L3Q73_18290	COG3275	phosphorelay sensor kinase activity
L3Q73_18310	COG1538	Outer membrane efflux protein
L3Q73_18315	COG0697	spore germination
L3Q73_18340	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L3Q73_18345	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L3Q73_18350	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L3Q73_18355	COG0772	Belongs to the SEDS family
L3Q73_18380	COG4974	Belongs to the 'phage' integrase family
L3Q73_18385	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L3Q73_18395	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
L3Q73_18405	COG2197	response regulator
L3Q73_18420	COG0793	Belongs to the peptidase S41A family
L3Q73_18425	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
L3Q73_18430	COG0795	lipopolysaccharide-transporting ATPase activity
L3Q73_18470	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L3Q73_18470	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L3Q73_18480	COG0004	ammonium transporteR
L3Q73_18485	COG0347	Belongs to the P(II) protein family
L3Q73_18545	COG0659	secondary active sulfate transmembrane transporter activity
L3Q73_18550	COG0589	response to stress
L3Q73_18585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L3Q73_18595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L3Q73_18615	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
L3Q73_18630	COG0318	PFAM AMP-dependent synthetase and ligase
L3Q73_18640	COG0477	Major facilitator Superfamily
L3Q73_18645	COG2860	membrane
L3Q73_18655	COG1253	flavin adenine dinucleotide binding
L3Q73_18675	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L3Q73_18715	COG0655	NAD(P)H dehydrogenase (quinone) activity
L3Q73_18725	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L3Q73_18795	COG0758	DNA mediated transformation
L3Q73_18805	COG0697	spore germination
L3Q73_18810	COG1309	transcriptional regulator
L3Q73_18825	COG0386	Belongs to the glutathione peroxidase family
L3Q73_18890	COG1121	(ABC) transporter
L3Q73_18895	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L3Q73_18900	COG1280	lysine exporter protein (LysE YggA)
L3Q73_18905	COG2837	iron assimilation
L3Q73_18915	COG0281	malic enzyme
L3Q73_18960	COG0519	Catalyzes the synthesis of GMP from XMP
L3Q73_18960	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L3Q73_18965	COG4399	Belongs to the UPF0754 family
L3Q73_18970	COG2259	Doxx family
L3Q73_18975	COG0586	Pfam SNARE associated Golgi protein
L3Q73_18990	COG1192	Involved in chromosome partitioning
L3Q73_19000	COG0271	Belongs to the BolA IbaG family
L3Q73_19020	COG2267	carboxylic ester hydrolase activity
L3Q73_19040	COG3321	synthase
L3Q73_19040	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
L3Q73_19040	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L3Q73_19040	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L3Q73_19045	COG1960	acyl-CoA dehydrogenase activity
L3Q73_19055	COG2197	response regulator
L3Q73_19065	COG3916	Acyl-homoserine-lactone synthase
L3Q73_19070	COG0477	Major facilitator Superfamily
L3Q73_19075	COG1024	Enoyl-CoA hydratase
L3Q73_19080	COG1024	Enoyl-CoA hydratase
L3Q73_19085	COG1960	acyl-CoA dehydrogenase activity
L3Q73_19090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L3Q73_19110	COG1113	amino acid transport
L3Q73_19115	COG1113	amino acid transport
L3Q73_19120	COG0251	oxidation-reduction process
L3Q73_19160	COG0564	pseudouridine synthase activity
L3Q73_19220	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L3Q73_19235	COG1802	Transcriptional regulator
L3Q73_19245	COG1448	Aminotransferase
L3Q73_19250	COG0277	FAD linked oxidase domain protein
L3Q73_19260	COG2186	Transcriptional regulator
L3Q73_19270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L3Q73_19275	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L3Q73_19290	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L3Q73_19295	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
L3Q73_19300	COG1216	Glycosyl transferase, family 2
L3Q73_19330	COG2089	acid synthase
L3Q73_19345	COG1083	cytidylyl-transferase
L3Q73_19350	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
L3Q73_19355	COG1086	Polysaccharide biosynthesis protein
L3Q73_19360	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L3Q73_19365	COG1596	polysaccharide export
L3Q73_19390	COG0728	peptidoglycan biosynthetic process
L3Q73_19395	COG3023	N-Acetylmuramoyl-L-alanine amidase
L3Q73_19455	COG0546	phosphoglycolate phosphatase activity
L3Q73_19460	COG1028	Short-chain dehydrogenase reductase Sdr
L3Q73_19480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L3Q73_19485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L3Q73_19490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3Q73_19495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L3Q73_19500	COG1116	anion transmembrane transporter activity
L3Q73_19505	COG1309	transcriptional regulator
L3Q73_19510	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L3Q73_19520	COG0196	riboflavin kinase activity
L3Q73_19525	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
L3Q73_19535	COG1047	Peptidyl-prolyl cis-trans
L3Q73_19575	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L3Q73_19580	COG0657	acetylesterase activity
L3Q73_19600	COG0583	DNA-binding transcription factor activity
L3Q73_19630	COG2951	lytic endotransglycosylase activity
L3Q73_19635	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L3Q73_19650	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
L3Q73_19660	COG0671	phosphoesterase, PA-phosphatase related
L3Q73_19665	COG0861	Integral membrane protein TerC family
L3Q73_19675	COG0754	glutathionylspermidine amidase activity
L3Q73_19685	COG0402	S-adenosylhomocysteine deaminase activity
L3Q73_19700	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L3Q73_19705	COG1230	cation diffusion facilitator family transporter
L3Q73_19720	COG0706	membrane insertase activity
L3Q73_19745	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
L3Q73_19810	COG4683	PFAM Phage derived protein Gp49-like (DUF891)