locus-tag	class	description
D7A46_00085	COG0484	heat shock protein binding
D7A46_00560	COG0174	glutamine synthetase
D7A46_00610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D7A46_00615	COG2814	Major facilitator Superfamily
D7A46_00630	COG0583	DNA-binding transcription factor activity
D7A46_00645	COG1187	pseudouridine synthase activity
D7A46_00665	COG0802	atpase or kinase
D7A46_00670	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D7A46_00680	COG1923	regulation of RNA biosynthetic process
D7A46_00685	COG0697	spore germination
D7A46_00700	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D7A46_00715	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D7A46_00715	COG0519	Catalyzes the synthesis of GMP from XMP
D7A46_00720	COG4302	ethanolamine ammonia-lyase activity
D7A46_00725	COG4303	Ethanolamine ammonia lyase large subunit
D7A46_00730	COG0531	amino acid
D7A46_00750	COG1454	alcohol dehydrogenase
D7A46_00755	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D7A46_00765	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
D7A46_00785	COG0308	aminopeptidase N
D7A46_00815	COG1605	Chorismate mutase
D7A46_00835	COG1309	transcriptional regulator
D7A46_00845	COG0668	transmembrane transport
D7A46_00880	COG4773	Receptor
D7A46_00900	COG0488	(ABC) transporter
D7A46_00905	COG0589	response to stress
D7A46_00920	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D7A46_00930	COG3135	benzoate transporter
D7A46_00935	COG1522	sequence-specific DNA binding
D7A46_00950	COG0583	DNA-binding transcription factor activity
D7A46_00960	COG0183	Belongs to the thiolase family
D7A46_00990	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D7A46_01000	COG0824	Thioesterase
D7A46_01005	COG1454	alcohol dehydrogenase
D7A46_01015	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D7A46_01035	COG0069	glutamate synthase activity
D7A46_01200	COG5410	chromosome segregation
D7A46_01325	COG0739	heme binding
D7A46_01390	COG2814	Major facilitator Superfamily
D7A46_01405	COG0511	ligase activity, forming carbon-carbon bonds
D7A46_01425	COG1116	anion transmembrane transporter activity
D7A46_01425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D7A46_01430	COG0745	RESPONSE REGULATOR receiver
D7A46_01440	COG2146	nitrite reductase [NAD(P)H] activity
D7A46_01440	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D7A46_01445	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D7A46_01450	COG0243	molybdopterin cofactor binding
D7A46_01460	COG0243	molybdopterin cofactor binding
D7A46_01465	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D7A46_01480	COG0315	cyclic pyranopterin monophosphate synthase activity
D7A46_01480	COG0521	Mo-molybdopterin cofactor biosynthetic process
D7A46_01485	COG0303	'Molybdopterin
D7A46_01495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D7A46_01500	COG0697	spore germination
D7A46_01520	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
D7A46_01525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D7A46_01585	COG2204	response regulator
D7A46_01590	COG3852	Histidine kinase
D7A46_01610	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D7A46_01615	COG0575	Belongs to the CDS family
D7A46_01650	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D7A46_01665	COG2137	regulation of response to DNA damage stimulus
D7A46_01675	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D7A46_01680	COG1011	Hydrolase
D7A46_01705	COG1522	sequence-specific DNA binding
D7A46_01715	COG1113	amino acid transport
D7A46_01730	COG0659	secondary active sulfate transmembrane transporter activity
D7A46_01735	COG2135	peptidase activity
D7A46_01750	COG3300	MHYT domain
D7A46_01750	COG5001	Diguanylate cyclase
D7A46_01770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D7A46_01770	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D7A46_01770	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
D7A46_01775	COG1105	Belongs to the carbohydrate kinase PfkB family
D7A46_01780	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D7A46_01780	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D7A46_01810	COG0024	Methionine aminopeptidase
D7A46_01815	COG0583	DNA-binding transcription factor activity
D7A46_01825	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
D7A46_01830	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D7A46_01835	COG0517	IMP dehydrogenase activity
D7A46_01835	COG0516	GMP reductase activity
D7A46_01860	COG0552	protein localization to endoplasmic reticulum
D7A46_01870	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
D7A46_01885	COG4890	Cyd operon protein YbgT
D7A46_01890	COG1294	oxidase, subunit
D7A46_01905	COG1585	Membrane protein implicated in regulation of membrane protease activity
D7A46_01915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D7A46_01920	COG4774	siderophore transport
D7A46_01935	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D7A46_01940	COG0569	domain protein
D7A46_01945	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D7A46_01975	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
D7A46_01980	COG0542	response to heat
D7A46_01990	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D7A46_02005	COG1902	pentaerythritol trinitrate reductase activity
D7A46_02005	COG0446	pyridine nucleotide-disulphide oxidoreductase
D7A46_02050	COG2323	membrane
D7A46_02055	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
D7A46_02065	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D7A46_02070	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D7A46_02075	COG0183	Belongs to the thiolase family
D7A46_02080	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D7A46_02085	COG0596	Alpha beta hydrolase
D7A46_02090	COG2271	Major facilitator Superfamily
D7A46_02095	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D7A46_02100	COG3485	protocatechuate 3,4-dioxygenase
D7A46_02105	COG3485	protocatechuate 3,4-dioxygenase
D7A46_02110	COG0710	3-dehydroquinate dehydratase activity
D7A46_02115	COG3420	alginic acid biosynthetic process
D7A46_02120	COG3659	wide pore channel activity
D7A46_02125	COG4993	Dehydrogenase
D7A46_02135	COG2391	methyltransferase activity
D7A46_02150	COG1414	Transcriptional regulator
D7A46_02155	COG0583	DNA-binding transcription factor activity
D7A46_02160	COG1960	acyl-CoA dehydrogenase activity
D7A46_02185	COG2814	Major facilitator Superfamily
D7A46_02195	COG0154	amidase activity
D7A46_02215	COG4638	Rieske (2fe-2S)
D7A46_02225	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_02235	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D7A46_02245	COG3733	amine oxidase
D7A46_02255	COG1012	belongs to the aldehyde dehydrogenase family
D7A46_02265	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D7A46_02270	COG0183	Belongs to the thiolase family
D7A46_02275	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D7A46_02280	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D7A46_02290	COG4829	muconolactone delta-isomerase
D7A46_02295	COG4948	Mandelate Racemase Muconate Lactonizing
D7A46_02300	COG0583	DNA-binding transcription factor activity
D7A46_02310	COG2186	Transcriptional regulator
D7A46_02330	COG1012	belongs to the aldehyde dehydrogenase family
D7A46_02350	COG1960	acyl-CoA dehydrogenase activity
D7A46_02355	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_02360	COG3829	transcription factor binding
D7A46_02370	COG3162	membrane
D7A46_02385	COG1012	belongs to the aldehyde dehydrogenase family
D7A46_02400	COG0753	catalase activity
D7A46_02425	COG1846	Transcriptional regulator
D7A46_02430	COG0446	pyridine nucleotide-disulphide oxidoreductase
D7A46_02430	COG1902	pentaerythritol trinitrate reductase activity
D7A46_02440	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D7A46_02470	COG1309	transcriptional regulator
D7A46_02480	COG1335	isochorismatase
D7A46_02485	COG0583	DNA-binding transcription factor activity
D7A46_02495	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D7A46_02495	COG0475	glutathione-regulated potassium exporter activity
D7A46_02505	COG1473	amidohydrolase
D7A46_02520	COG2831	hemolysin activation secretion protein
D7A46_02525	COG3210	domain, Protein
D7A46_02570	COG0583	DNA-binding transcription factor activity
D7A46_02595	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D7A46_02600	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
D7A46_02620	COG1566	PFAM secretion protein HlyD family protein
D7A46_02635	COG1012	belongs to the aldehyde dehydrogenase family
D7A46_02640	COG0129	dihydroxy-acid dehydratase activity
D7A46_02650	COG0583	DNA-binding transcription factor activity
D7A46_02655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D7A46_02665	COG2084	Dehydrogenase
D7A46_02670	COG2207	Transcriptional regulator
D7A46_02685	COG1064	alcohol dehydrogenase
D7A46_02700	COG1120	ATPase activity
D7A46_02720	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D7A46_02840	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
D7A46_02895	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_02910	COG2207	Transcriptional regulator
D7A46_02920	COG2205	protein histidine kinase activity
D7A46_02925	COG0745	RESPONSE REGULATOR receiver
D7A46_02930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7A46_02935	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D7A46_02940	COG1538	Outer membrane efflux protein
D7A46_02950	COG2072	flavoprotein involved in K transport
D7A46_02970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D7A46_02990	COG3539	Fimbrial protein
D7A46_03020	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
D7A46_03030	COG0753	catalase activity
D7A46_03045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D7A46_03110	COG1535	isochorismatase
D7A46_03110	COG3433	isochorismatase activity
D7A46_03115	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_03120	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
D7A46_03125	COG4149	molybdate abc transporter
D7A46_03130	COG0725	ABC transporter, periplasmic molybdate-binding protein
D7A46_03140	COG4638	Rieske (2fe-2S)
D7A46_03145	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
D7A46_03150	COG0543	2 iron, 2 sulfur cluster binding
D7A46_03150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D7A46_03165	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D7A46_03175	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_03180	COG0412	Dienelactone hydrolase
D7A46_03190	COG2207	Transcriptional regulator
D7A46_03200	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_03205	COG2610	gluconate transmembrane transporter activity
D7A46_03215	COG0583	DNA-binding transcription factor activity
D7A46_03225	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D7A46_03230	COG2031	fatty acid transporter
D7A46_03235	COG0183	Belongs to the thiolase family
D7A46_03240	COG0583	DNA-binding transcription factor activity
D7A46_03245	COG0583	DNA-binding transcription factor activity
D7A46_03260	COG1027	Aspartate ammonia-lyase
D7A46_03270	COG0477	Major facilitator Superfamily
D7A46_03290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7A46_03295	COG4521	taurine ABC transporter
D7A46_03320	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D7A46_03325	COG1733	regulation of RNA biosynthetic process
D7A46_03330	COG2207	Transcriptional regulator
D7A46_03330	COG3708	Transcriptional regulator
D7A46_03345	COG0730	response to heat
D7A46_03355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D7A46_03355	COG3453	Protein conserved in bacteria
D7A46_03365	COG3781	membrane
D7A46_03370	COG1063	alcohol dehydrogenase
D7A46_03380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D7A46_03385	COG0508	dehydrogenase complex catalyzes the overall conversion of
D7A46_03390	COG0022	dehydrogenase e1 component
D7A46_03395	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D7A46_03400	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D7A46_03415	COG3706	GGDEF domain
D7A46_03430	COG0133	tryptophan synthase activity
D7A46_03440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D7A46_03475	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D7A46_03500	COG2226	methyltransferase
D7A46_03555	COG0842	Transport permease protein
D7A46_03560	COG0842	Transport permease protein
D7A46_03565	COG1131	(ABC) transporter
D7A46_03580	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D7A46_03585	COG4773	Receptor
D7A46_03605	COG0730	response to heat
D7A46_03610	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D7A46_03630	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
D7A46_03690	COG4264	IucA IucC family
D7A46_03695	COG4264	IucA IucC family
D7A46_03715	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D7A46_03730	COG1960	acyl-CoA dehydrogenase activity
D7A46_03735	COG1960	acyl-CoA dehydrogenase activity
D7A46_03740	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D7A46_03745	COG2207	Transcriptional regulator
D7A46_03750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D7A46_03755	COG0776	regulation of translation
D7A46_03780	COG0822	iron-sulfur transferase activity
D7A46_03785	COG0316	Belongs to the HesB IscA family
D7A46_03815	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D7A46_03835	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
D7A46_03840	COG0702	epimerase
D7A46_03875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D7A46_03885	COG0339	signal peptide processing
D7A46_03935	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
D7A46_03940	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
D7A46_03970	COG0776	regulation of translation
D7A46_03990	COG0590	tRNA wobble adenosine to inosine editing
D7A46_04020	COG2165	general secretion pathway protein
D7A46_04035	COG0084	hydrolase, TatD family'
D7A46_04055	COG1663	tetraacyldisaccharide 4'-kinase activity
D7A46_04060	COG1132	(ABC) transporter
D7A46_04070	COG0811	peptide transport
D7A46_04075	COG1475	DNA binding
D7A46_04080	COG1192	Involved in chromosome partitioning
D7A46_04090	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D7A46_04105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D7A46_04110	COG0191	fructose-bisphosphate aldolase activity
D7A46_04130	COG0424	maF-like protein
D7A46_04135	COG2850	peptidyl-arginine hydroxylation
D7A46_04145	COG0640	Transcriptional regulator
D7A46_04160	COG3619	membrane
D7A46_04165	COG3122	Protein conserved in bacteria
D7A46_04170	COG1132	(ABC) transporter
D7A46_04190	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D7A46_04195	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D7A46_04205	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
D7A46_04205	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
D7A46_04205	COG0506	proline dehydrogenase activity
D7A46_04210	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D7A46_04225	COG3698	Phosphodiester glycosidase
D7A46_04235	COG2353	YceI-like domain
D7A46_04245	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D7A46_04290	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D7A46_04290	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
D7A46_04315	COG3539	Fimbrial protein
D7A46_04320	COG3121	Chaperone
D7A46_04350	COG0697	spore germination
D7A46_04360	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D7A46_04370	COG0583	DNA-binding transcription factor activity
D7A46_04390	COG1309	transcriptional regulator
D7A46_04405	COG1522	sequence-specific DNA binding
D7A46_04415	COG1126	abc transporter atp-binding protein
D7A46_04420	COG0765	amino acid transport
D7A46_04425	COG0765	amino acid transport
D7A46_04455	COG1464	Belongs to the NlpA lipoprotein family
D7A46_04465	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D7A46_04470	COG2011	ABC-type metal ion transport system permease component
D7A46_04475	COG0012	GTP binding
D7A46_04500	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
D7A46_04540	COG0386	Belongs to the glutathione peroxidase family
D7A46_04550	COG0436	Aminotransferase
D7A46_04590	COG3634	alkyl hydroperoxide reductase activity
D7A46_04605	COG0583	DNA-binding transcription factor activity
D7A46_04610	COG0798	PFAM Bile acid sodium symporter
D7A46_04615	COG0640	Transcriptional regulator
D7A46_04630	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D7A46_04640	COG0583	DNA-binding transcription factor activity
D7A46_04650	COG1953	Uracil, thiamine, allantoin
D7A46_04660	COG2175	clavaminate synthase activity
D7A46_04665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7A46_04670	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
D7A46_04675	COG4521	taurine ABC transporter
D7A46_04685	COG0477	Major facilitator Superfamily
D7A46_04710	COG1271	oxidase subunit
D7A46_04715	COG1294	oxidase, subunit
D7A46_04725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D7A46_04745	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D7A46_04765	COG3052	prosthetic group binding
D7A46_04770	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
D7A46_04780	COG2814	Major facilitator Superfamily
D7A46_04800	COG1346	cytolysis
D7A46_04810	COG0583	DNA-binding transcription factor activity
D7A46_04815	COG0625	glutathione transferase activity
D7A46_04820	COG0625	glutathione transferase activity
D7A46_04825	COG0583	DNA-binding transcription factor activity
D7A46_04840	COG1045	serine acetyltransferase
D7A46_04845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D7A46_04850	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D7A46_04860	COG1280	lysine exporter protein (LysE YggA)
D7A46_04875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D7A46_04880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D7A46_04885	COG1126	abc transporter atp-binding protein
D7A46_04890	COG0765	amino acid transport
D7A46_04895	COG0765	amino acid transport
D7A46_04915	COG2205	protein histidine kinase activity
D7A46_04915	COG0784	Response regulator, receiver
D7A46_04935	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D7A46_04955	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_05000	COG0583	DNA-binding transcription factor activity
D7A46_05020	COG0318	PFAM AMP-dependent synthetase and ligase
D7A46_05025	COG1309	transcriptional regulator
D7A46_05030	COG1960	acyl-CoA dehydrogenase activity
D7A46_05035	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D7A46_05040	COG1024	Enoyl-CoA hydratase
D7A46_05055	COG0583	DNA-binding transcription factor activity
D7A46_05070	COG1960	acyl-CoA dehydrogenase activity
D7A46_05080	COG2814	Major facilitator Superfamily
D7A46_05090	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D7A46_05095	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D7A46_05100	COG2814	Major facilitator Superfamily
D7A46_05105	COG1960	acyl-CoA dehydrogenase activity
D7A46_05110	COG1024	Enoyl-CoA hydratase
D7A46_05115	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_05120	COG1250	3-hydroxyacyl-CoA dehydrogenase
D7A46_05125	COG0183	Belongs to the thiolase family
D7A46_05135	COG2814	Major facilitator Superfamily
D7A46_05145	COG1024	Enoyl-CoA hydratase
D7A46_05160	COG1960	acyl-CoA dehydrogenase activity
D7A46_05165	COG2814	Major facilitator Superfamily
D7A46_05170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D7A46_05175	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D7A46_05190	COG3842	ATPase activity
D7A46_05195	COG1840	ABC-type Fe3 transport system, periplasmic component
D7A46_05205	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D7A46_05210	COG1414	Transcriptional regulator
D7A46_05220	COG0583	DNA-binding transcription factor activity
D7A46_05225	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D7A46_05230	COG1012	belongs to the aldehyde dehydrogenase family
D7A46_05240	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D7A46_05250	COG1012	belongs to the aldehyde dehydrogenase family
D7A46_05255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D7A46_05260	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D7A46_05265	COG2267	carboxylic ester hydrolase activity
D7A46_05285	COG3038	cytochrome b561
D7A46_05290	COG0753	catalase activity
D7A46_05330	COG2050	protein possibly involved in aromatic compounds catabolism
D7A46_05340	COG3327	negative regulation of DNA-templated transcription, initiation
D7A46_05345	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
D7A46_05350	COG0183	Belongs to the thiolase family
D7A46_05355	COG1250	3-hydroxyacyl-CoA dehydrogenase
D7A46_05360	COG1024	Enoyl-CoA hydratase
D7A46_05365	COG1024	Enoyl-CoA hydratase
D7A46_05370	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D7A46_05375	COG2151	metal-sulfur cluster biosynthetic enzyme
D7A46_05380	COG3396	Phenylacetate-CoA oxygenase
D7A46_05385	COG3460	Phenylacetate-CoA oxygenase
D7A46_05390	COG3396	Phenylacetate-CoA oxygenase
D7A46_05395	COG1012	belongs to the aldehyde dehydrogenase family
D7A46_05395	COG2030	dehydratase
D7A46_05400	COG1760	l-serine dehydratase
D7A46_05405	COG0531	amino acid
D7A46_05410	COG1012	belongs to the aldehyde dehydrogenase family
D7A46_05425	COG0446	pyridine nucleotide-disulphide oxidoreductase
D7A46_05435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D7A46_05455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D7A46_05470	COG0789	Transcriptional regulator
D7A46_05485	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D7A46_05500	COG2807	transmembrane transport
D7A46_05505	COG0590	tRNA wobble adenosine to inosine editing
D7A46_05515	COG0583	DNA-binding transcription factor activity
D7A46_05555	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
D7A46_05555	COG2885	chlorophyll binding
D7A46_05625	COG1116	anion transmembrane transporter activity
D7A46_05630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D7A46_05640	COG0864	Transcriptional regulator
D7A46_05660	COG2249	NAD(P)H dehydrogenase (quinone) activity
D7A46_05665	COG0439	Biotin carboxylase
D7A46_05680	COG1063	alcohol dehydrogenase
D7A46_05690	COG1309	transcriptional regulator
D7A46_05715	COG0038	chloride channel
D7A46_05720	COG4770	biotin carboxylase activity
D7A46_05740	COG1914	H( )-stimulated, divalent metal cation uptake system
D7A46_05745	COG0583	DNA-binding transcription factor activity
D7A46_05760	COG3209	COG3209 Rhs family protein
D7A46_05765	COG3501	Rhs element vgr protein
D7A46_05800	COG1250	3-hydroxyacyl-CoA dehydrogenase
D7A46_05820	COG2814	Major facilitator Superfamily
D7A46_05835	COG1560	Kdo2-lipid A biosynthetic process
D7A46_05845	COG5006	permease, DMT superfamily
D7A46_05850	COG1522	sequence-specific DNA binding
D7A46_05865	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
D7A46_05905	COG1538	Outer membrane efflux protein
D7A46_05910	COG1137	ATPase activity
D7A46_05915	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
D7A46_05925	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
D7A46_05930	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D7A46_05930	COG0517	IMP dehydrogenase activity
D7A46_05965	COG1733	regulation of RNA biosynthetic process
D7A46_05970	COG2814	Major facilitator Superfamily
D7A46_06010	COG1278	Cold shock
D7A46_06015	COG1280	lysine exporter protein (LysE YggA)
D7A46_06050	COG1570	exodeoxyribonuclease VII activity
D7A46_06105	COG0583	DNA-binding transcription factor activity
D7A46_06110	COG4638	Rieske (2fe-2S)
D7A46_06115	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
D7A46_06120	COG0543	2 iron, 2 sulfur cluster binding
D7A46_06120	COG0633	Ferredoxin
D7A46_06125	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_06130	COG3135	benzoate transporter
D7A46_06135	COG2814	Major facilitator Superfamily
D7A46_06150	COG1643	Atp-dependent helicase
D7A46_06155	COG0450	alkyl hydroperoxide reductase
D7A46_06165	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
D7A46_06175	COG3634	alkyl hydroperoxide reductase activity
D7A46_06195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D7A46_06200	COG0625	glutathione transferase activity
D7A46_06210	COG2885	chlorophyll binding
D7A46_06260	COG1765	OsmC-like protein
D7A46_06280	COG3316	Transposase and inactivated derivatives
D7A46_06310	COG3316	Transposase and inactivated derivatives
D7A46_06330	COG3316	Transposase and inactivated derivatives
D7A46_06340	COG3316	Transposase and inactivated derivatives
D7A46_06365	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
D7A46_06375	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D7A46_06395	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D7A46_06405	COG3038	cytochrome b561
D7A46_06410	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
D7A46_06415	COG2252	PERMEase
D7A46_06425	COG2072	flavoprotein involved in K transport
D7A46_06440	COG1741	Belongs to the pirin family
D7A46_06445	COG1309	transcriptional regulator
D7A46_06455	COG3316	Transposase and inactivated derivatives
D7A46_06470	COG0446	pyridine nucleotide-disulphide oxidoreductase
D7A46_06470	COG1902	pentaerythritol trinitrate reductase activity
D7A46_06480	COG3706	GGDEF domain
D7A46_06480	COG2203	Gaf domain
D7A46_06480	COG4251	negative regulation of phosphorylation
D7A46_06480	COG5001	Diguanylate cyclase
D7A46_06490	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D7A46_06510	COG4172	Belongs to the ABC transporter superfamily
D7A46_06515	COG4239	(ABC) transporter, permease
D7A46_06520	COG4174	ABC transporter (Permease)
D7A46_06530	COG0741	lytic transglycosylase activity
D7A46_06530	COG1388	LysM domain
D7A46_06530	COG0741	lytic transglycosylase activity
D7A46_06530	COG1388	LysM domain
D7A46_06535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D7A46_06575	COG0583	DNA-binding transcription factor activity
D7A46_06580	COG1279	arginine transmembrane transporter activity
D7A46_06600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D7A46_06605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D7A46_06610	COG0006	proline dipeptidase activity
D7A46_06645	COG2194	sulfuric ester hydrolase activity
D7A46_06690	COG0739	heme binding
D7A46_07020	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D7A46_07045	COG3384	dioxygenase
D7A46_07055	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D7A46_07060	COG2878	Part of a membrane complex involved in electron transport
D7A46_07065	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D7A46_07090	COG0768	penicillin binding
D7A46_07095	COG0742	ribosomal rna small subunit methyltransferase
D7A46_07110	COG0830	nickel cation binding
D7A46_07120	COG0804	urea catabolic process
D7A46_07160	COG1253	flavin adenine dinucleotide binding
D7A46_07170	COG2851	Citrate transporter
D7A46_07225	COG1773	rubredoxin
D7A46_07230	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D7A46_07240	COG0583	DNA-binding transcription factor activity
D7A46_07265	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
D7A46_07270	COG4181	ATPase activity
D7A46_07315	COG1262	PFAM Formylglycine-generating sulfatase enzyme
D7A46_07335	COG0306	phosphate transporter
D7A46_07345	COG3958	Transketolase
D7A46_07350	COG3959	Transketolase, thiamine diphosphate binding domain
D7A46_07355	COG2271	Major facilitator Superfamily
D7A46_07360	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_07365	COG0583	DNA-binding transcription factor activity
D7A46_07385	COG2223	nitrite transmembrane transporter activity
D7A46_07390	COG2207	Transcriptional regulator
D7A46_07395	COG2066	Belongs to the glutaminase family
D7A46_07400	COG0242	peptide deformylase activity
D7A46_07405	COG0477	Major facilitator Superfamily
D7A46_07415	COG0028	Belongs to the TPP enzyme family
D7A46_07430	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_07435	COG2267	carboxylic ester hydrolase activity
D7A46_07445	COG2271	Major facilitator Superfamily
D7A46_07450	COG0446	pyridine nucleotide-disulphide oxidoreductase
D7A46_07460	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_07480	COG1414	Transcriptional regulator
D7A46_07495	COG1024	Enoyl-CoA hydratase
D7A46_07505	COG1215	transferase activity, transferring glycosyl groups
D7A46_07510	COG1649	PFAM Uncharacterised BCR, COG1649
D7A46_07510	COG0726	polysaccharide deacetylase
D7A46_07520	COG4681	YaeQ
D7A46_07530	COG0523	cobalamin synthesis protein
D7A46_07540	COG1607	acyl-coa hydrolase
D7A46_07550	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D7A46_07555	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D7A46_07560	COG1309	transcriptional regulator
D7A46_07585	COG2040	homocysteine
D7A46_07590	COG0531	amino acid
D7A46_07645	COG1595	DNA-templated transcription, initiation
D7A46_07655	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D7A46_07660	COG0477	Major facilitator Superfamily
D7A46_07680	COG0084	hydrolase, TatD family'
D7A46_07770	COG0582	viral genome integration into host DNA
D7A46_07865	COG0592	DNA-directed DNA polymerase activity
D7A46_07905	COG2026	Addiction module toxin, RelE StbE family
D7A46_08100	COG1484	DNA-dependent DNA replication
D7A46_08190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D7A46_08255	COG0405	Gamma-glutamyltransferase
D7A46_08260	COG2814	Major facilitator Superfamily
D7A46_08270	COG2050	protein possibly involved in aromatic compounds catabolism
D7A46_08285	COG1090	epimerase
D7A46_08305	COG0420	3'-5' exonuclease activity
D7A46_08330	COG0735	belongs to the Fur family
D7A46_08335	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D7A46_08360	COG0121	glutamine amidotransferase
D7A46_08375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D7A46_08385	COG0210	DNA helicase
D7A46_08390	COG2885	chlorophyll binding
D7A46_08395	COG0204	Acyl-transferase
D7A46_08410	COG2894	cell division
D7A46_08430	COG1280	lysine exporter protein (LysE YggA)
D7A46_08435	COG1674	ftsk spoiiie
D7A46_08435	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D7A46_08440	COG0492	ferredoxin-NADP+ reductase activity
D7A46_08445	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
D7A46_08455	COG0456	acetyltransferase
D7A46_08515	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D7A46_08515	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
D7A46_08535	COG1012	belongs to the aldehyde dehydrogenase family
D7A46_08555	COG0473	3-isopropylmalate dehydrogenase activity
D7A46_08560	COG0583	DNA-binding transcription factor activity
D7A46_08580	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
D7A46_08605	COG0564	pseudouridine synthase activity
D7A46_08615	COG0358	DNA primase activity
D7A46_08630	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
D7A46_08660	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D7A46_08690	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D7A46_08700	COG0351	phosphomethylpyrimidine kinase
D7A46_08700	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D7A46_08700	COG0352	thiamine-phosphate diphosphorylase activity
D7A46_08705	COG1652	LysM domain
D7A46_08730	COG1399	metal-binding, possibly nucleic acid-binding protein
D7A46_08735	COG3101	peptidyl-lysine hydroxylation
D7A46_08740	COG0009	L-threonylcarbamoyladenylate synthase
D7A46_08745	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
D7A46_08750	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D7A46_08765	COG4106	trans-aconitate 2-methyltransferase activity
D7A46_08780	COG2226	methyltransferase
D7A46_08780	COG0596	Alpha beta hydrolase
D7A46_08780	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D7A46_08785	COG1877	trehalose-phosphatase activity
D7A46_08790	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
D7A46_08795	COG2223	nitrite transmembrane transporter activity
D7A46_08815	COG1196	nuclear chromosome segregation
D7A46_08825	COG0730	response to heat
D7A46_08840	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D7A46_08850	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D7A46_08910	COG0489	protein tyrosine kinase activity
D7A46_08920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D7A46_08920	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D7A46_08950	COG2515	1-aminocyclopropane-1-carboxylate deaminase
D7A46_08955	COG2081	HI0933 family
D7A46_08965	COG0668	transmembrane transport
D7A46_08985	COG0583	DNA-binding transcription factor activity
D7A46_09005	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D7A46_09010	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D7A46_09040	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
D7A46_09075	COG2205	protein histidine kinase activity
D7A46_09080	COG0745	RESPONSE REGULATOR receiver
D7A46_09100	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D7A46_09110	COG2205	protein histidine kinase activity
D7A46_09180	COG4993	Dehydrogenase
D7A46_09200	COG0384	phenazine biosynthesis protein PhzF
D7A46_09230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D7A46_09235	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D7A46_09245	COG0583	DNA-binding transcription factor activity
D7A46_09265	COG1473	amidohydrolase
D7A46_09275	COG0583	DNA-binding transcription factor activity
D7A46_09295	COG0583	DNA-binding transcription factor activity
D7A46_09300	COG1053	succinate dehydrogenase
D7A46_09310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D7A46_09315	COG2814	Major facilitator Superfamily
D7A46_09320	COG1960	acyl-CoA dehydrogenase activity
D7A46_09325	COG0583	DNA-binding transcription factor activity
D7A46_09330	COG1063	alcohol dehydrogenase
D7A46_09360	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
D7A46_09365	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
D7A46_09370	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D7A46_09385	COG3667	copper resistance
D7A46_09390	COG2132	Multicopper oxidase
D7A46_09400	COG0561	phosphatase activity
D7A46_09405	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D7A46_09430	COG1214	PFAM Peptidase M22, glycoprotease
D7A46_09485	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D7A46_09495	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D7A46_09500	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
D7A46_09505	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D7A46_09565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D7A46_09575	COG1846	Transcriptional regulator
D7A46_09580	COG1764	response to oxidative stress
D7A46_09630	COG0037	tRNA processing
D7A46_09640	COG0248	Ppx GppA phosphatase
D7A46_09670	COG0072	phenylalanine-tRNA ligase activity
D7A46_09695	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D7A46_09710	COG1238	metal cluster binding
D7A46_09715	COG0625	glutathione transferase activity
D7A46_09735	COG0318	PFAM AMP-dependent synthetase and ligase
D7A46_09740	COG3028	Belongs to the UPF0307 family
D7A46_09745	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D7A46_09765	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D7A46_09770	COG0617	tRNA 3'-terminal CCA addition
D7A46_09775	COG1555	photosystem II stabilization
D7A46_09780	COG3956	TIGRFAM MazG family protein
D7A46_09790	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D7A46_09810	COG5002	protein histidine kinase activity
D7A46_09810	COG0784	Response regulator, receiver
D7A46_09810	COG2205	protein histidine kinase activity
D7A46_09815	COG1024	Enoyl-CoA hydratase
D7A46_09820	COG2084	Dehydrogenase
D7A46_09825	COG3622	Belongs to the hyi family
D7A46_09840	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
D7A46_09845	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
D7A46_09850	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
D7A46_09855	COG0697	spore germination
D7A46_09865	COG2814	Major facilitator Superfamily
D7A46_09870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D7A46_09880	COG0583	DNA-binding transcription factor activity
D7A46_09890	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D7A46_09905	COG0084	hydrolase, TatD family'
D7A46_09920	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
D7A46_09955	COG0440	acetolactate synthase activity
D7A46_09960	COG0028	Belongs to the TPP enzyme family
D7A46_09985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7A46_09990	COG1136	(ABC) transporter
D7A46_09990	COG0577	efflux transmembrane transporter activity
D7A46_09995	COG1538	Outer membrane efflux protein
D7A46_10010	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
D7A46_10015	COG1162	GTPase activity
D7A46_10025	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D7A46_10045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D7A46_10050	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_10090	COG2986	histidine ammonia-lyase
D7A46_10105	COG0318	PFAM AMP-dependent synthetase and ligase
D7A46_10115	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D7A46_10120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D7A46_10160	COG1426	Protein conserved in bacteria
D7A46_10195	COG0793	Belongs to the peptidase S41A family
D7A46_10210	COG2267	carboxylic ester hydrolase activity
D7A46_10220	COG1012	belongs to the aldehyde dehydrogenase family
D7A46_10225	COG3265	gluconokinase activity
D7A46_10235	COG0800	Aldolase
D7A46_10250	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D7A46_10255	COG0280	phosphate acetyltransferase
D7A46_10255	COG0857	belongs to the CobB CobQ family
D7A46_10260	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
D7A46_10260	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
D7A46_10280	COG0740	serine-type endopeptidase activity
D7A46_10290	COG4774	siderophore transport
D7A46_10300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D7A46_10310	COG2813	Specifically methylates the guanine in position
D7A46_10310	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D7A46_10410	COG0788	formyltetrahydrofolate deformylase activity
D7A46_10425	COG0227	Belongs to the bacterial ribosomal protein bL28 family
D7A46_10430	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D7A46_10435	COG4651	solute:proton antiporter activity
D7A46_10435	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D7A46_10455	COG0724	RNA recognition motif
D7A46_10460	COG0210	DNA helicase
D7A46_10485	COG1733	regulation of RNA biosynthetic process
D7A46_10505	COG1280	lysine exporter protein (LysE YggA)
D7A46_10510	COG1560	Kdo2-lipid A biosynthetic process
D7A46_10520	COG1301	dicarboxylic acid transport
D7A46_10575	COG0473	3-isopropylmalate dehydrogenase activity
D7A46_10640	COG0583	DNA-binding transcription factor activity
D7A46_10650	COG0625	glutathione transferase activity
D7A46_10655	COG2378	regulation of single-species biofilm formation
D7A46_10660	COG0546	phosphoglycolate phosphatase activity
D7A46_10675	COG1530	ribonuclease E activity
D7A46_10695	COG0583	DNA-binding transcription factor activity
D7A46_10700	COG4221	oxidoreductase activity
D7A46_10705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D7A46_10715	COG0534	Mate efflux family protein
D7A46_10730	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
D7A46_10770	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
D7A46_10775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D7A46_10790	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D7A46_10800	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
D7A46_10800	COG0644	oxidoreductase
D7A46_10805	COG0425	Belongs to the sulfur carrier protein TusA family
D7A46_10810	COG4535	Mg2 and Co2 transporter CorC
D7A46_10820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D7A46_10840	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D7A46_10845	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D7A46_10845	COG0475	glutathione-regulated potassium exporter activity
D7A46_10850	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D7A46_10860	COG0484	heat shock protein binding
D7A46_10865	COG0789	Transcriptional regulator
D7A46_10870	COG0598	Magnesium transport protein CorA
D7A46_10890	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D7A46_10895	COG1074	ATP-dependent DNA helicase activity
D7A46_10900	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
D7A46_10920	COG2226	methyltransferase
D7A46_10935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D7A46_10940	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D7A46_10955	COG2111	Na H antiporter
D7A46_10955	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D7A46_10960	COG1006	Multisubunit Na H antiporter MnhC subunit
D7A46_10965	COG0651	ATP synthesis coupled electron transport
D7A46_10975	COG2212	antiporter activity
D7A46_10995	COG0195	Participates in both transcription termination and antitermination
D7A46_11045	COG0237	dephospho-CoA kinase activity
D7A46_11055	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D7A46_11070	COG0497	DNA recombination
D7A46_11080	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D7A46_11110	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D7A46_11110	COG2169	Transcriptional regulator
D7A46_11115	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D7A46_11185	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D7A46_11200	COG0326	Molecular chaperone. Has ATPase activity
D7A46_11215	COG2056	Na+-H+ antiporter family
D7A46_11220	COG0596	Alpha beta hydrolase
D7A46_11315	COG0546	phosphoglycolate phosphatase activity
D7A46_11320	COG1716	ATPase activity
D7A46_11365	COG0181	hydroxymethylbilane synthase activity
D7A46_11375	COG3275	phosphorelay sensor kinase activity
D7A46_11395	COG1538	Outer membrane efflux protein
D7A46_11400	COG0697	spore germination
D7A46_11425	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D7A46_11430	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D7A46_11435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D7A46_11440	COG0772	Belongs to the SEDS family
D7A46_11465	COG4974	Belongs to the 'phage' integrase family
D7A46_11470	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D7A46_11480	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D7A46_11505	COG0793	Belongs to the peptidase S41A family
D7A46_11510	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
D7A46_11515	COG0795	lipopolysaccharide-transporting ATPase activity
D7A46_11555	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D7A46_11555	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D7A46_11565	COG0004	ammonium transporteR
D7A46_11570	COG0347	Belongs to the P(II) protein family
D7A46_11580	COG0606	chelatase, subunit chli
D7A46_11650	COG1061	Type III restriction enzyme res subunit
D7A46_11665	COG0659	secondary active sulfate transmembrane transporter activity
D7A46_11670	COG0589	response to stress
D7A46_11715	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D7A46_11765	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
D7A46_11810	COG1061	Type III restriction enzyme res subunit
D7A46_11825	COG0659	secondary active sulfate transmembrane transporter activity
D7A46_11830	COG0589	response to stress
D7A46_11860	COG0606	chelatase, subunit chli
D7A46_11875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D7A46_11890	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
D7A46_11905	COG0318	PFAM AMP-dependent synthetase and ligase
D7A46_11915	COG0477	Major facilitator Superfamily
D7A46_11920	COG2860	membrane
D7A46_11930	COG1253	flavin adenine dinucleotide binding
D7A46_11950	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D7A46_11985	COG0655	NAD(P)H dehydrogenase (quinone) activity
D7A46_11995	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D7A46_12030	COG1309	transcriptional regulator
D7A46_12065	COG0758	DNA mediated transformation
D7A46_12075	COG0697	spore germination
D7A46_12080	COG1309	transcriptional regulator
D7A46_12095	COG0386	Belongs to the glutathione peroxidase family
D7A46_12160	COG1121	(ABC) transporter
D7A46_12165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D7A46_12170	COG1280	lysine exporter protein (LysE YggA)
D7A46_12175	COG2837	iron assimilation
D7A46_12185	COG0281	malic enzyme
D7A46_12230	COG0519	Catalyzes the synthesis of GMP from XMP
D7A46_12230	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D7A46_12235	COG4399	Belongs to the UPF0754 family
D7A46_12240	COG2259	Doxx family
D7A46_12245	COG0586	Pfam SNARE associated Golgi protein
D7A46_12260	COG1192	Involved in chromosome partitioning
D7A46_12270	COG0271	Belongs to the BolA IbaG family
D7A46_12290	COG2267	carboxylic ester hydrolase activity
D7A46_12310	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D7A46_12310	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
D7A46_12310	COG3321	synthase
D7A46_12310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D7A46_12315	COG1960	acyl-CoA dehydrogenase activity
D7A46_12325	COG2197	response regulator
D7A46_12335	COG3916	Acyl-homoserine-lactone synthase
D7A46_12340	COG0477	Major facilitator Superfamily
D7A46_12345	COG1024	Enoyl-CoA hydratase
D7A46_12350	COG1024	Enoyl-CoA hydratase
D7A46_12355	COG1960	acyl-CoA dehydrogenase activity
D7A46_12360	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D7A46_12380	COG1113	amino acid transport
D7A46_12385	COG1113	amino acid transport
D7A46_12390	COG0251	oxidation-reduction process
D7A46_12405	COG1522	sequence-specific DNA binding
D7A46_12430	COG0564	pseudouridine synthase activity
D7A46_12495	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D7A46_12510	COG1802	Transcriptional regulator
D7A46_12520	COG1448	Aminotransferase
D7A46_12525	COG0277	FAD linked oxidase domain protein
D7A46_12535	COG2186	Transcriptional regulator
D7A46_12545	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D7A46_12550	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D7A46_12565	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D7A46_12570	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D7A46_12595	COG0438	transferase activity, transferring glycosyl groups
D7A46_12625	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
D7A46_12665	COG0728	peptidoglycan biosynthetic process
D7A46_12670	COG3023	N-Acetylmuramoyl-L-alanine amidase
D7A46_12725	COG0546	phosphoglycolate phosphatase activity
D7A46_12730	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_12750	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D7A46_12755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D7A46_12760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D7A46_12765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7A46_12770	COG1116	anion transmembrane transporter activity
D7A46_12775	COG1309	transcriptional regulator
D7A46_12780	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D7A46_12795	COG1061	Type III restriction enzyme res subunit
D7A46_12820	COG0196	riboflavin kinase activity
D7A46_12825	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D7A46_12835	COG1047	Peptidyl-prolyl cis-trans
D7A46_12875	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D7A46_12930	COG2951	lytic endotransglycosylase activity
D7A46_12935	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D7A46_12955	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D7A46_12965	COG0671	phosphoesterase, PA-phosphatase related
D7A46_12970	COG0861	Integral membrane protein TerC family
D7A46_12980	COG0754	glutathionylspermidine amidase activity
D7A46_12990	COG0402	S-adenosylhomocysteine deaminase activity
D7A46_13005	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D7A46_13010	COG1230	cation diffusion facilitator family transporter
D7A46_13025	COG0706	membrane insertase activity
D7A46_13040	COG0230	Belongs to the bacterial ribosomal protein bL34 family
D7A46_13050	COG0592	DNA-directed DNA polymerase activity
D7A46_13060	COG0187	DNA topoisomerase II activity
D7A46_13070	COG0586	Pfam SNARE associated Golgi protein
D7A46_13075	COG0488	(ABC) transporter
D7A46_13100	COG0596	Alpha beta hydrolase
D7A46_13105	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
D7A46_13110	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D7A46_13155	COG0733	neurotransmitter:sodium symporter activity
D7A46_13195	COG2233	PERMEase
D7A46_13210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7A46_13245	COG2814	Major facilitator Superfamily
D7A46_13250	COG0656	L-ascorbic acid biosynthetic process
D7A46_13255	COG0583	DNA-binding transcription factor activity
D7A46_13270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D7A46_13275	COG1064	alcohol dehydrogenase
D7A46_13280	COG2818	Glycosylase
D7A46_13295	COG1194	a g-specific adenine glycosylase
D7A46_13315	COG2983	Belongs to the UPF0260 family
D7A46_13320	COG2133	pyrroloquinoline quinone binding
D7A46_13325	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D7A46_13330	COG2116	formate transmembrane transporter activity
D7A46_13350	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D7A46_13355	COG1335	isochorismatase
D7A46_13360	COG0385	Bile acid
D7A46_13365	COG0534	Mate efflux family protein
D7A46_13370	COG1683	Conserved Protein
D7A46_13390	COG0625	glutathione transferase activity
D7A46_13400	COG1113	amino acid transport
D7A46_13410	COG0523	cobalamin synthesis protein
D7A46_13420	COG2188	Transcriptional regulator
D7A46_13450	COG0010	Belongs to the arginase family
D7A46_13465	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D7A46_13470	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D7A46_13480	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D7A46_13485	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D7A46_13590	COG0534	Mate efflux family protein
D7A46_13595	COG0436	Aminotransferase
D7A46_13600	COG2733	membrane
D7A46_13615	COG2918	glutathione biosynthetic process
D7A46_13625	COG3501	Rhs element vgr protein
D7A46_13630	COG1388	LysM domain
D7A46_13630	COG0791	NLP P60 protein
D7A46_13645	COG3150	esterase
D7A46_13655	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_13660	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
D7A46_13670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D7A46_13680	COG2233	PERMEase
D7A46_13685	COG2351	hydroxyisourate hydrolase activity
D7A46_13720	COG3706	GGDEF domain
D7A46_13735	COG1393	Belongs to the ArsC family
D7A46_13740	COG0708	Exodeoxyribonuclease III
D7A46_13760	COG0189	ligase activity
D7A46_13780	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D7A46_13790	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D7A46_13805	COG4942	peptidase
D7A46_13815	COG0508	dehydrogenase complex catalyzes the overall conversion of
D7A46_13825	COG2119	membrane
D7A46_13830	COG4774	siderophore transport
D7A46_13835	COG0426	domain, Protein
D7A46_13835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D7A46_13860	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D7A46_13880	COG1902	pentaerythritol trinitrate reductase activity
D7A46_13885	COG1519	Transferase
D7A46_13890	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D7A46_13895	COG0668	transmembrane transport
D7A46_13905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D7A46_13910	COG1335	isochorismatase
D7A46_13915	COG1522	sequence-specific DNA binding
D7A46_13920	COG3328	transposase activity
D7A46_13945	COG2205	protein histidine kinase activity
D7A46_13945	COG2198	Histidine kinase
D7A46_13945	COG0784	Response regulator, receiver
D7A46_13950	COG3162	membrane
D7A46_13955	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D7A46_13965	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D7A46_13975	COG3706	GGDEF domain
D7A46_13985	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D7A46_13990	COG1309	transcriptional regulator
D7A46_14010	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D7A46_14010	COG0352	thiamine-phosphate diphosphorylase activity
D7A46_14010	COG0351	phosphomethylpyrimidine kinase
D7A46_14020	COG2814	Major facilitator Superfamily
D7A46_14035	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
D7A46_14045	COG1113	amino acid transport
D7A46_14055	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D7A46_14060	COG1012	belongs to the aldehyde dehydrogenase family
D7A46_14070	COG1335	isochorismatase
D7A46_14100	COG2814	Major facilitator Superfamily
D7A46_14105	COG0583	DNA-binding transcription factor activity
D7A46_14125	COG0667	Aldo Keto reductase
D7A46_14160	COG1733	regulation of RNA biosynthetic process
D7A46_14170	COG2249	NAD(P)H dehydrogenase (quinone) activity
D7A46_14235	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D7A46_14250	COG2329	Antibiotic biosynthesis monooxygenase
D7A46_14280	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D7A46_14325	COG0745	RESPONSE REGULATOR receiver
D7A46_14335	COG0659	secondary active sulfate transmembrane transporter activity
D7A46_14340	COG4221	oxidoreductase activity
D7A46_14350	COG0488	(ABC) transporter
D7A46_14435	COG0833	amino acid
D7A46_14480	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D7A46_14485	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D7A46_14500	COG2226	methyltransferase
D7A46_14550	COG0070	glutamate synthase
D7A46_14550	COG0069	glutamate synthase activity
D7A46_14550	COG0067	glutamate synthase
D7A46_14555	COG0493	'glutamate synthase
D7A46_14565	COG1704	LemA family
D7A46_14570	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
D7A46_14590	COG3307	-O-antigen
D7A46_14610	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D7A46_14625	COG0194	GDP metabolic process
D7A46_14675	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D7A46_14695	COG5380	lipid catabolic process
D7A46_14700	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
D7A46_14725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D7A46_14730	COG0277	FAD linked oxidase domain protein
D7A46_14740	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D7A46_14745	COG2249	NAD(P)H dehydrogenase (quinone) activity
D7A46_14760	COG1289	transmembrane transporter activity
D7A46_14770	COG0628	permease
D7A46_14775	COG1192	Involved in chromosome partitioning
D7A46_14805	COG0833	amino acid
D7A46_14810	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D7A46_14815	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D7A46_14825	COG1012	belongs to the aldehyde dehydrogenase family
D7A46_14865	COG0583	DNA-binding transcription factor activity
D7A46_14910	COG0517	IMP dehydrogenase activity
D7A46_14915	COG1983	PspC domain protein
D7A46_14925	COG1960	acyl-CoA dehydrogenase activity
D7A46_14940	COG0408	coproporphyrinogen oxidase activity
D7A46_14960	COG0513	Belongs to the DEAD box helicase family
D7A46_14965	COG1127	ABC transporter
D7A46_14970	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
D7A46_14980	COG2854	intermembrane phospholipid transfer
D7A46_14990	COG0598	Magnesium transport protein CorA
D7A46_15000	COG0494	nUDIX hydrolase
D7A46_15005	COG1040	competence protein
D7A46_15010	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D7A46_15030	COG1946	Acyl-CoA thioesterase
D7A46_15035	COG1301	dicarboxylic acid transport
D7A46_15050	COG1959	2 iron, 2 sulfur cluster binding
D7A46_15055	COG1017	nitric oxide dioxygenase activity
D7A46_15055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D7A46_15060	COG0433	COG0433 Predicted ATPase
D7A46_15065	COG0626	cystathionine gamma-synthase activity
D7A46_15185	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D7A46_15195	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
D7A46_15220	COG1960	acyl-CoA dehydrogenase activity
D7A46_15225	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
D7A46_15255	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
D7A46_15260	COG0339	signal peptide processing
D7A46_15265	COG0557	exoribonuclease II activity
D7A46_15310	COG0179	Fumarylacetoacetate (FAA) hydrolase
D7A46_15315	COG2169	Transcriptional regulator
D7A46_15320	COG0697	spore germination
D7A46_15325	COG1295	ribonuclease BN
D7A46_15360	COG1702	phosphate starvation-inducible protein PhoH
D7A46_15370	COG1196	nuclear chromosome segregation
D7A46_15370	COG0741	lytic transglycosylase activity
D7A46_15370	COG0739	heme binding
D7A46_15400	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
D7A46_15405	COG1183	phosphatidylcholine synthase activity
D7A46_15450	COG1960	acyl-CoA dehydrogenase activity
D7A46_15455	COG1309	transcriptional regulator
D7A46_15470	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D7A46_15475	COG1960	acyl-CoA dehydrogenase activity
D7A46_15495	COG2969	positive regulation of protein catabolic process
D7A46_15505	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D7A46_15520	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D7A46_15525	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D7A46_15545	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D7A46_15555	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D7A46_15560	COG1408	metallophosphoesterase
D7A46_15570	COG2199	diguanylate cyclase activity
D7A46_15615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D7A46_15615	COG3453	Protein conserved in bacteria
D7A46_15630	COG1607	acyl-coa hydrolase
D7A46_15660	COG2350	Protein conserved in bacteria
D7A46_15670	COG0613	PHP domain protein
D7A46_15675	COG3781	membrane
D7A46_15685	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D7A46_15690	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D7A46_15700	COG1862	Preprotein translocase
D7A46_15730	COG2205	protein histidine kinase activity
D7A46_15735	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
D7A46_15755	COG0726	polysaccharide deacetylase
D7A46_15760	COG0463	Glycosyl transferase, family 2
D7A46_15765	COG0438	transferase activity, transferring glycosyl groups
D7A46_15830	COG0625	glutathione transferase activity
D7A46_15835	COG0583	DNA-binding transcription factor activity
D7A46_15840	COG1960	acyl-CoA dehydrogenase activity
D7A46_15845	COG1960	acyl-CoA dehydrogenase activity
D7A46_15855	COG2205	protein histidine kinase activity
D7A46_15860	COG0745	RESPONSE REGULATOR receiver
D7A46_15865	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
D7A46_15885	COG2096	Adenosyltransferase
D7A46_15900	COG0133	tryptophan synthase activity
D7A46_15935	COG0285	dihydrofolate synthase activity
D7A46_15955	COG0450	alkyl hydroperoxide reductase
D7A46_15970	COG0477	Major facilitator Superfamily
D7A46_15975	COG1272	protein, Hemolysin III
D7A46_16005	COG0183	Belongs to the thiolase family
D7A46_16010	COG2207	Transcriptional regulator
D7A46_16030	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D7A46_16050	COG0183	Belongs to the thiolase family
D7A46_16060	COG2885	chlorophyll binding
D7A46_16060	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
D7A46_16070	COG1690	Belongs to the RtcB family
D7A46_16075	COG0833	amino acid
D7A46_16085	COG2233	PERMEase
D7A46_16115	COG2094	Belongs to the DNA glycosylase MPG family
D7A46_16120	COG4772	TonB-dependent receptor
D7A46_16135	COG1902	pentaerythritol trinitrate reductase activity
D7A46_16140	COG0679	Auxin Efflux Carrier
D7A46_16150	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D7A46_16155	COG0354	folic acid binding
D7A46_16165	COG3189	MarR family transcriptional regulator
D7A46_16170	COG2824	Alkylphosphonate utilization operon protein PhnA
D7A46_16175	COG3422	double-strand break repair
D7A46_16215	COG0840	transmembrane signaling receptor activity
D7A46_16235	COG5510	response to toxic substance
D7A46_16245	COG2832	Protein of unknown function (DUF454)
D7A46_16250	COG1376	ErfK ybiS ycfS ynhG family protein
D7A46_16300	COG1289	transmembrane transporter activity
D7A46_16305	COG2814	Major facilitator Superfamily
D7A46_16325	COG1115	amino acid carrier protein
D7A46_16330	COG1752	Esterase of the alpha-beta hydrolase superfamily
D7A46_16335	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D7A46_16340	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
D7A46_16380	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D7A46_16390	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D7A46_16395	COG1077	Cell shape determining protein MreB Mrl
D7A46_16400	COG1792	Involved in formation and maintenance of cell shape
D7A46_16405	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D7A46_16410	COG0424	maF-like protein
D7A46_16415	COG1530	ribonuclease E activity
D7A46_16425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D7A46_16445	COG2249	NAD(P)H dehydrogenase (quinone) activity
D7A46_16470	COG2207	Transcriptional regulator
D7A46_16490	COG1113	amino acid transport
D7A46_16495	COG2828	Protein conserved in bacteria
D7A46_16500	COG0142	geranyltranstransferase activity
D7A46_16505	COG2315	Protein conserved in bacteria
D7A46_16520	COG1752	Esterase of the alpha-beta hydrolase superfamily
D7A46_16540	COG2194	sulfuric ester hydrolase activity
D7A46_16545	COG0745	RESPONSE REGULATOR receiver
D7A46_16550	COG0642	Histidine kinase
D7A46_16560	COG0004	ammonium transporteR
D7A46_16570	COG0583	DNA-binding transcription factor activity
D7A46_16590	COG0525	valine-tRNA ligase activity
D7A46_16600	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_16610	COG0393	Putative heavy-metal-binding
D7A46_16615	COG0393	Putative heavy-metal-binding
D7A46_16620	COG1538	Outer membrane efflux protein
D7A46_16630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7A46_16635	COG0671	phosphoesterase, PA-phosphatase related
D7A46_16665	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
D7A46_16680	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D7A46_16680	COG1648	precorrin-2 dehydrogenase activity
D7A46_16685	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D7A46_16690	COG1733	regulation of RNA biosynthetic process
D7A46_16700	COG0531	amino acid
D7A46_16715	COG0321	lipoyl(octanoyl) transferase activity
D7A46_16720	COG2921	Belongs to the UPF0250 family
D7A46_16760	COG2009	succinate dehydrogenase
D7A46_16765	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
D7A46_16770	COG1053	succinate dehydrogenase
D7A46_16775	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D7A46_16800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D7A46_16820	COG2354	Protein conserved in bacteria
D7A46_16825	COG2321	neutral zinc metallopeptidase
D7A46_16875	COG2843	Capsule synthesis protein
D7A46_16890	COG0589	response to stress
D7A46_16910	COG0505	Belongs to the CarA family
D7A46_16935	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D7A46_16940	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D7A46_16990	COG0477	Major facilitator Superfamily
D7A46_16995	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D7A46_17015	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D7A46_17045	COG0584	glycerophosphoryl diester phosphodiesterase
D7A46_17065	COG0741	lytic transglycosylase activity
D7A46_17090	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D7A46_17105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D7A46_17135	COG0778	Nitroreductase
D7A46_17150	COG1929	Belongs to the glycerate kinase type-1 family
D7A46_17155	COG0243	molybdopterin cofactor binding
D7A46_17160	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D7A46_17165	COG3339	Conserved Protein
D7A46_17175	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
D7A46_17190	COG1113	amino acid transport
D7A46_17200	COG0019	diaminopimelate decarboxylase activity
D7A46_17210	COG1280	lysine exporter protein (LysE YggA)
D7A46_17215	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
D7A46_17245	COG0463	Glycosyl transferase, family 2
D7A46_17265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7A46_17295	COG4591	ABC-type transport system involved in lipoprotein release permease component
D7A46_17300	COG1136	(ABC) transporter
D7A46_17305	COG2333	competence protein COMEC
D7A46_17305	COG0658	competence protein
D7A46_17315	COG0616	signal peptide processing
D7A46_17315	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
D7A46_17320	COG0596	Alpha beta hydrolase
D7A46_17325	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D7A46_17335	COG0628	permease
D7A46_17370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D7A46_17390	COG0823	Involved in the tonB-independent uptake of proteins
D7A46_17410	COG0824	Thioesterase
D7A46_17415	COG1473	amidohydrolase
D7A46_17435	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D7A46_17435	COG0047	phosphoribosylformylglycinamidine synthase activity
D7A46_17440	COG2814	Major facilitator Superfamily
D7A46_17445	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D7A46_17450	COG1024	Enoyl-CoA hydratase
D7A46_17455	COG1056	cytidyltransferase-related domain
D7A46_17455	COG1051	belongs to the nudix hydrolase family
D7A46_17465	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D7A46_17480	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
D7A46_17495	COG4625	pathogenesis
D7A46_17500	COG0583	DNA-binding transcription factor activity
D7A46_17505	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
D7A46_17510	COG4208	sulfate ABC transporter
D7A46_17515	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
D7A46_17525	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
D7A46_17530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D7A46_17535	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D7A46_17555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D7A46_17570	COG0681	Belongs to the peptidase S26 family
D7A46_17585	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D7A46_17595	COG1381	Involved in DNA repair and RecF pathway recombination
D7A46_17600	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
D7A46_17610	COG4221	oxidoreductase activity
D7A46_17660	COG0556	nucleotide-excision repair
D7A46_17715	COG2070	2-Nitropropane dioxygenase
D7A46_17745	COG1215	transferase activity, transferring glycosyl groups
D7A46_17760	COG0415	Belongs to the DNA photolyase family
D7A46_17770	COG1252	NADH dehydrogenase
D7A46_17775	COG1686	Belongs to the peptidase S11 family
D7A46_17790	COG1187	pseudouridine synthase activity
D7A46_17815	COG0477	Major facilitator Superfamily
D7A46_17820	COG0583	DNA-binding transcription factor activity
D7A46_17835	COG0612	Peptidase, M16
D7A46_17860	COG0352	thiamine-phosphate diphosphorylase activity
D7A46_17895	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D7A46_17910	COG1309	transcriptional regulator
D7A46_17920	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D7A46_17925	COG0076	glutamate decarboxylase activity
D7A46_17935	COG1522	sequence-specific DNA binding
D7A46_17940	COG3961	Belongs to the TPP enzyme family
D7A46_17945	COG1113	amino acid transport
D7A46_17950	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D7A46_17955	COG0573	inorganic phosphate transmembrane transporter activity
D7A46_17965	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D7A46_17970	COG0616	signal peptide processing
D7A46_17980	COG3328	transposase activity
D7A46_18010	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D7A46_18015	COG1686	Belongs to the peptidase S11 family
D7A46_18040	COG0583	DNA-binding transcription factor activity
D7A46_18045	COG1067	ATP-dependent peptidase activity
D7A46_18090	COG1966	Carbon starvation protein
D7A46_18095	COG2879	small protein
D7A46_18130	COG2508	Transcriptional regulator
D7A46_18130	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D7A46_18150	COG1113	amino acid transport
D7A46_18155	COG0583	DNA-binding transcription factor activity
D7A46_18160	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D7A46_18165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D7A46_18180	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D7A46_18185	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
D7A46_18185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D7A46_18220	COG2814	Major facilitator Superfamily
D7A46_18225	COG4948	Mandelate Racemase Muconate Lactonizing
D7A46_18235	COG1309	transcriptional regulator
D7A46_18255	COG1741	Belongs to the pirin family
D7A46_18265	COG2964	Protein conserved in bacteria
D7A46_18280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D7A46_18285	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D7A46_18290	COG4605	iron ion homeostasis
D7A46_18295	COG4604	ABC transporter, ATP-binding protein
D7A46_18300	COG4607	ABC-type enterochelin transport system periplasmic component
D7A46_18305	COG4774	siderophore transport
D7A46_18315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D7A46_18320	COG1021	2,3-dihydroxybenzoate-AMP ligase
D7A46_18325	COG1535	isochorismatase
D7A46_18325	COG3433	isochorismatase activity
D7A46_18340	COG1132	(ABC) transporter
D7A46_18350	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
D7A46_18360	COG1169	isochorismate synthase
D7A46_18375	COG3739	integral membrane protein
D7A46_18410	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D7A46_18440	COG0308	aminopeptidase N
D7A46_18445	COG0512	Glutamine amidotransferase of anthranilate synthase
D7A46_18455	COG3104	oligopeptide transport
D7A46_18470	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
D7A46_18505	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D7A46_18510	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D7A46_18515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D7A46_18535	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D7A46_18540	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D7A46_18545	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
D7A46_18560	COG1960	acyl-CoA dehydrogenase activity
D7A46_18565	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D7A46_18570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D7A46_18580	COG2223	nitrite transmembrane transporter activity
D7A46_18590	COG0024	Methionine aminopeptidase
D7A46_18595	COG0052	Belongs to the universal ribosomal protein uS2 family
D7A46_18610	COG2207	Transcriptional regulator
D7A46_18635	COG2951	lytic endotransglycosylase activity
D7A46_18640	COG0772	Belongs to the SEDS family
D7A46_18655	COG0842	Transport permease protein
D7A46_18660	COG1131	(ABC) transporter
D7A46_18695	COG1538	Outer membrane efflux protein
D7A46_18705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7A46_18720	COG4215	(ABC) transporter
D7A46_18725	COG4160	amino acid transport
D7A46_18730	COG4598	ABC transporter
D7A46_18740	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
D7A46_18750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D7A46_18765	COG1720	tRNA m6t6A37 methyltransferase activity
D7A46_18785	COG0745	RESPONSE REGULATOR receiver
D7A46_18790	COG0642	Histidine kinase
D7A46_18800	COG0494	nUDIX hydrolase
D7A46_18810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D7A46_18815	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D7A46_18820	COG3139	Protein of unknown function (DUF1315)
D7A46_18825	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D7A46_18835	COG1301	dicarboxylic acid transport
D7A46_18840	COG1960	acyl-CoA dehydrogenase activity
D7A46_18845	COG2819	hydrolase of the alpha beta superfamily
D7A46_18855	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D7A46_18865	COG2195	Cleaves the N-terminal amino acid of tripeptides
D7A46_18870	COG1234	tRNA 3'-trailer cleavage
D7A46_18900	COG2363	Small membrane protein
D7A46_18920	COG0513	Belongs to the DEAD box helicase family
D7A46_18930	COG0778	Nitroreductase
D7A46_18960	COG1286	toxin biosynthetic process
D7A46_18985	COG4783	chaperone-mediated protein folding
D7A46_18990	COG1610	YqeY-like protein
D7A46_18995	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D7A46_19090	COG3111	PFAM Bacterial OB fold (BOF) protein
D7A46_19115	COG3243	poly(R)-hydroxyalkanoic acid synthase
D7A46_19120	COG0786	glutamate:sodium symporter activity
D7A46_19130	COG2186	Transcriptional regulator
D7A46_19180	COG0477	Major facilitator Superfamily
D7A46_19210	COG2985	domain, Protein
D7A46_19220	COG2995	paraquat-inducible protein a
D7A46_19225	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
D7A46_19225	COG3008	intermembrane lipid transfer
D7A46_19250	COG0482	sulfurtransferase activity
D7A46_19270	COG3173	Aminoglycoside phosphotransferase
D7A46_19280	COG2433	Pfam Transposase IS66
D7A46_19305	COG3316	Transposase and inactivated derivatives
D7A46_19320	COG1301	dicarboxylic acid transport
D7A46_19330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D7A46_19335	COG2011	ABC-type metal ion transport system permease component
D7A46_19340	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D7A46_19345	COG1464	Belongs to the NlpA lipoprotein family
D7A46_19350	COG0151	Belongs to the GarS family
D7A46_19355	COG0138	bifunctional purine biosynthesis protein purh
D7A46_19360	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
D7A46_19390	COG2308	Evidence 4 Homologs of previously reported genes of
D7A46_19400	COG1305	Transglutaminase-like
D7A46_19410	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D7A46_19415	COG0305	Participates in initiation and elongation during chromosome replication
D7A46_19440	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D7A46_19450	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D7A46_19455	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D7A46_19480	COG1649	PFAM Uncharacterised BCR, COG1649
D7A46_19480	COG0726	polysaccharide deacetylase
D7A46_19485	COG1215	transferase activity, transferring glycosyl groups
D7A46_19490	COG3658	cytochrome
D7A46_19500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D7A46_19520	COG0583	DNA-binding transcription factor activity
D7A46_19540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7A46_19545	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D7A46_19560	COG1960	acyl-CoA dehydrogenase activity
D7A46_19565	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D7A46_19570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D7A46_19595	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
D7A46_19600	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system