locus-tag	class	description
IAG34_00040	COG1047	Peptidyl-prolyl cis-trans
IAG34_00050	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IAG34_00055	COG0196	riboflavin kinase activity
IAG34_00065	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IAG34_00070	COG1309	transcriptional regulator
IAG34_00075	COG1116	anion transmembrane transporter activity
IAG34_00080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAG34_00085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAG34_00090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IAG34_00095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IAG34_00115	COG1028	Short-chain dehydrogenase reductase Sdr
IAG34_00120	COG0546	phosphoglycolate phosphatase activity
IAG34_00190	COG3023	N-Acetylmuramoyl-L-alanine amidase
IAG34_00195	COG0728	peptidoglycan biosynthetic process
IAG34_00225	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IAG34_00235	COG1215	transferase activity, transferring glycosyl groups
IAG34_00260	COG0297	glycogen (starch) synthase activity
IAG34_00270	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IAG34_00275	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IAG34_00290	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IAG34_00300	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IAG34_00310	COG2186	Transcriptional regulator
IAG34_00320	COG0277	FAD linked oxidase domain protein
IAG34_00325	COG1448	Aminotransferase
IAG34_00335	COG1802	Transcriptional regulator
IAG34_00350	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IAG34_00380	COG0564	pseudouridine synthase activity
IAG34_00420	COG0251	oxidation-reduction process
IAG34_00425	COG1113	amino acid transport
IAG34_00430	COG1113	amino acid transport
IAG34_00450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IAG34_00455	COG1960	acyl-CoA dehydrogenase activity
IAG34_00460	COG1024	Enoyl-CoA hydratase
IAG34_00465	COG1024	Enoyl-CoA hydratase
IAG34_00470	COG0477	Major facilitator Superfamily
IAG34_00475	COG3916	Acyl-homoserine-lactone synthase
IAG34_00485	COG2197	response regulator
IAG34_00520	COG0271	Belongs to the BolA IbaG family
IAG34_00530	COG1192	Involved in chromosome partitioning
IAG34_00545	COG0586	Pfam SNARE associated Golgi protein
IAG34_00550	COG2259	Doxx family
IAG34_00555	COG4399	Belongs to the UPF0754 family
IAG34_00560	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IAG34_00560	COG0519	Catalyzes the synthesis of GMP from XMP
IAG34_00605	COG0281	malic enzyme
IAG34_00615	COG2837	iron assimilation
IAG34_00620	COG1280	lysine exporter protein (LysE YggA)
IAG34_00625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IAG34_00630	COG1121	(ABC) transporter
IAG34_00695	COG0386	Belongs to the glutathione peroxidase family
IAG34_00710	COG1309	transcriptional regulator
IAG34_00715	COG0697	spore germination
IAG34_00725	COG0758	DNA mediated transformation
IAG34_00760	COG1309	transcriptional regulator
IAG34_00795	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IAG34_00805	COG0655	NAD(P)H dehydrogenase (quinone) activity
IAG34_00845	COG4452	Inner membrane protein CreD
IAG34_00850	COG2205	protein histidine kinase activity
IAG34_00855	COG0745	RESPONSE REGULATOR receiver
IAG34_00860	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IAG34_00870	COG0477	Major facilitator Superfamily
IAG34_00880	COG1253	flavin adenine dinucleotide binding
IAG34_00890	COG2860	membrane
IAG34_00895	COG0477	Major facilitator Superfamily
IAG34_00905	COG0318	PFAM AMP-dependent synthetase and ligase
IAG34_00920	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IAG34_00935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAG34_00945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAG34_00950	COG0606	chelatase, subunit chli
IAG34_01000	COG2205	protein histidine kinase activity
IAG34_01015	COG2132	Multicopper oxidase
IAG34_01065	COG0606	chelatase, subunit chli
IAG34_01075	COG0347	Belongs to the P(II) protein family
IAG34_01080	COG0004	ammonium transporteR
IAG34_01090	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IAG34_01090	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IAG34_01130	COG0795	lipopolysaccharide-transporting ATPase activity
IAG34_01135	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IAG34_01140	COG0793	Belongs to the peptidase S41A family
IAG34_01155	COG2197	response regulator
IAG34_01165	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IAG34_01175	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IAG34_01180	COG4974	Belongs to the 'phage' integrase family
IAG34_01205	COG0772	Belongs to the SEDS family
IAG34_01210	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IAG34_01215	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IAG34_01220	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IAG34_01245	COG0697	spore germination
IAG34_01250	COG1538	Outer membrane efflux protein
IAG34_01270	COG3275	phosphorelay sensor kinase activity
IAG34_01280	COG0181	hydroxymethylbilane synthase activity
IAG34_01325	COG1716	ATPase activity
IAG34_01330	COG0546	phosphoglycolate phosphatase activity
IAG34_01425	COG0596	Alpha beta hydrolase
IAG34_01430	COG2056	Na+-H+ antiporter family
IAG34_01445	COG0326	Molecular chaperone. Has ATPase activity
IAG34_01460	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IAG34_01470	COG0789	Transcriptional regulator
IAG34_01520	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IAG34_01525	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IAG34_01525	COG2169	Transcriptional regulator
IAG34_01555	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IAG34_01565	COG0497	DNA recombination
IAG34_01580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IAG34_01590	COG0237	dephospho-CoA kinase activity
IAG34_01640	COG0195	Participates in both transcription termination and antitermination
IAG34_01655	COG1320	monovalent cation:proton antiporter activity
IAG34_01660	COG2212	antiporter activity
IAG34_01665	COG1863	multisubunit Na H antiporter MnhE subunit
IAG34_01670	COG0651	ATP synthesis coupled electron transport
IAG34_01675	COG1006	Multisubunit Na H antiporter MnhC subunit
IAG34_01680	COG2111	Na H antiporter
IAG34_01680	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IAG34_01695	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IAG34_01700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAG34_01715	COG2226	methyltransferase
IAG34_01735	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IAG34_01740	COG1074	ATP-dependent DNA helicase activity
IAG34_01745	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IAG34_01750	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IAG34_01765	COG0598	Magnesium transport protein CorA
IAG34_01770	COG0789	Transcriptional regulator
IAG34_01775	COG0484	heat shock protein binding
IAG34_01790	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IAG34_01790	COG0475	glutathione-regulated potassium exporter activity
IAG34_01795	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IAG34_01815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAG34_01825	COG4535	Mg2 and Co2 transporter CorC
IAG34_01830	COG0425	Belongs to the sulfur carrier protein TusA family
IAG34_01840	COG0644	oxidoreductase
IAG34_01840	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IAG34_01850	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IAG34_01865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAG34_01870	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IAG34_01880	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IAG34_01880	COG0493	'glutamate synthase
IAG34_01910	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IAG34_01925	COG0534	Mate efflux family protein
IAG34_01935	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IAG34_01940	COG4221	oxidoreductase activity
IAG34_01945	COG0583	DNA-binding transcription factor activity
IAG34_01960	COG0318	PFAM AMP-dependent synthetase and ligase
IAG34_01965	COG1530	ribonuclease E activity
IAG34_01975	COG0546	phosphoglycolate phosphatase activity
IAG34_01980	COG2378	regulation of single-species biofilm formation
IAG34_01985	COG0625	glutathione transferase activity
IAG34_01995	COG0583	DNA-binding transcription factor activity
IAG34_02025	COG0583	DNA-binding transcription factor activity
IAG34_02050	COG0473	3-isopropylmalate dehydrogenase activity
IAG34_02105	COG1301	dicarboxylic acid transport
IAG34_02115	COG1560	Kdo2-lipid A biosynthetic process
IAG34_02120	COG1280	lysine exporter protein (LysE YggA)
IAG34_02135	COG0488	(ABC) transporter
IAG34_02140	COG2900	Belongs to the SlyX family
IAG34_02150	COG1733	regulation of RNA biosynthetic process
IAG34_02175	COG0210	DNA helicase
IAG34_02180	COG0724	RNA recognition motif
IAG34_02200	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IAG34_02200	COG4651	solute:proton antiporter activity
IAG34_02225	COG0788	formyltetrahydrofolate deformylase activity
IAG34_02325	COG2813	Specifically methylates the guanine in position
IAG34_02325	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IAG34_02335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IAG34_02345	COG4774	siderophore transport
IAG34_02355	COG0740	serine-type endopeptidase activity
IAG34_02375	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IAG34_02375	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IAG34_02380	COG0280	phosphate acetyltransferase
IAG34_02380	COG0857	belongs to the CobB CobQ family
IAG34_02385	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IAG34_02395	COG0800	Aldolase
IAG34_02405	COG3265	gluconokinase activity
IAG34_02410	COG1012	belongs to the aldehyde dehydrogenase family
IAG34_02420	COG2267	carboxylic ester hydrolase activity
IAG34_02435	COG0793	Belongs to the peptidase S41A family
IAG34_02470	COG1426	Protein conserved in bacteria
IAG34_02510	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IAG34_02520	COG1162	GTPase activity
IAG34_02525	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IAG34_02540	COG1538	Outer membrane efflux protein
IAG34_02545	COG0577	efflux transmembrane transporter activity
IAG34_02545	COG1136	(ABC) transporter
IAG34_02550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAG34_02575	COG0028	Belongs to the TPP enzyme family
IAG34_02580	COG0440	acetolactate synthase activity
IAG34_02610	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IAG34_02625	COG0084	hydrolase, TatD family'
IAG34_02635	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IAG34_02645	COG0583	DNA-binding transcription factor activity
IAG34_02655	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IAG34_02730	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IAG34_02740	COG0732	type I restriction modification DNA specificity domain
IAG34_02755	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IAG34_02780	COG3220	belongs to the UPF0276 family
IAG34_02785	COG3219	Protein conserved in bacteria
IAG34_02790	COG1595	DNA-templated transcription, initiation
IAG34_02835	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IAG34_02840	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IAG34_02845	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IAG34_02850	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IAG34_02865	COG2814	Major facilitator Superfamily
IAG34_02875	COG0697	spore germination
IAG34_02905	COG3622	Belongs to the hyi family
IAG34_02910	COG2084	Dehydrogenase
IAG34_02915	COG1024	Enoyl-CoA hydratase
IAG34_02920	COG5002	protein histidine kinase activity
IAG34_02920	COG2205	protein histidine kinase activity
IAG34_02920	COG0784	Response regulator, receiver
IAG34_02940	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IAG34_02950	COG3956	TIGRFAM MazG family protein
IAG34_02955	COG1555	photosystem II stabilization
IAG34_02960	COG0617	tRNA 3'-terminal CCA addition
IAG34_02965	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IAG34_02985	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAG34_02990	COG3028	Belongs to the UPF0307 family
IAG34_02995	COG0318	PFAM AMP-dependent synthetase and ligase
IAG34_03010	COG0625	glutathione transferase activity
IAG34_03015	COG1238	metal cluster binding
IAG34_03055	COG0072	phenylalanine-tRNA ligase activity
IAG34_03085	COG0248	Ppx GppA phosphatase
IAG34_03095	COG0037	tRNA processing
IAG34_03135	COG1764	response to oxidative stress
IAG34_03140	COG1846	Transcriptional regulator
IAG34_03150	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IAG34_03210	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IAG34_03215	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IAG34_03220	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IAG34_03260	COG1214	PFAM Peptidase M22, glycoprotease
IAG34_03275	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IAG34_03285	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IAG34_03290	COG0561	phosphatase activity
IAG34_03300	COG2132	Multicopper oxidase
IAG34_03320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IAG34_03325	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IAG34_03330	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IAG34_03355	COG1598	PFAM Uncharacterised protein family UPF0150
IAG34_03360	COG1724	mRNA binding
IAG34_03370	COG4695	Portal protein
IAG34_03420	COG3409	Peptidoglycan-binding domain 1 protein
IAG34_03420	COG0860	N-Acetylmuramoyl-L-alanine amidase
IAG34_03600	COG0629	single-stranded DNA binding
IAG34_03605	COG0582	viral genome integration into host DNA
IAG34_03620	COG1063	alcohol dehydrogenase
IAG34_03625	COG0583	DNA-binding transcription factor activity
IAG34_03630	COG1960	acyl-CoA dehydrogenase activity
IAG34_03635	COG2814	Major facilitator Superfamily
IAG34_03640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG34_03645	COG1309	transcriptional regulator
IAG34_03660	COG1053	succinate dehydrogenase
IAG34_03665	COG0583	DNA-binding transcription factor activity
IAG34_03680	COG0583	DNA-binding transcription factor activity
IAG34_03690	COG0583	DNA-binding transcription factor activity
IAG34_03705	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IAG34_03740	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAG34_03760	COG0745	RESPONSE REGULATOR receiver
IAG34_03800	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IAG34_03830	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IAG34_03835	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IAG34_03855	COG0583	DNA-binding transcription factor activity
IAG34_03875	COG0668	transmembrane transport
IAG34_03885	COG2081	HI0933 family
IAG34_03890	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IAG34_03920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAG34_03920	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAG34_03930	COG0489	protein tyrosine kinase activity
IAG34_03985	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IAG34_03995	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IAG34_04015	COG0730	response to heat
IAG34_04025	COG1196	nuclear chromosome segregation
IAG34_04045	COG2223	nitrite transmembrane transporter activity
IAG34_04050	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IAG34_04060	COG0596	Alpha beta hydrolase
IAG34_04060	COG2226	methyltransferase
IAG34_04060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IAG34_04075	COG4106	trans-aconitate 2-methyltransferase activity
IAG34_04090	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IAG34_04095	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IAG34_04100	COG0009	L-threonylcarbamoyladenylate synthase
IAG34_04105	COG3101	peptidyl-lysine hydroxylation
IAG34_04110	COG1399	metal-binding, possibly nucleic acid-binding protein
IAG34_04135	COG1652	LysM domain
IAG34_04140	COG0352	thiamine-phosphate diphosphorylase activity
IAG34_04140	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IAG34_04140	COG0351	phosphomethylpyrimidine kinase
IAG34_04150	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IAG34_04180	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IAG34_04215	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IAG34_04230	COG0358	DNA primase activity
IAG34_04240	COG0564	pseudouridine synthase activity
IAG34_04265	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IAG34_04285	COG0583	DNA-binding transcription factor activity
IAG34_04290	COG0473	3-isopropylmalate dehydrogenase activity
IAG34_04300	COG0657	acetylesterase activity
IAG34_04310	COG1012	belongs to the aldehyde dehydrogenase family
IAG34_04330	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IAG34_04330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IAG34_04345	COG1981	membrane
IAG34_04390	COG0456	acetyltransferase
IAG34_04400	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IAG34_04405	COG0492	ferredoxin-NADP+ reductase activity
IAG34_04410	COG1674	ftsk spoiiie
IAG34_04410	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IAG34_04415	COG1280	lysine exporter protein (LysE YggA)
IAG34_04430	COG2894	cell division
IAG34_04445	COG0204	Acyl-transferase
IAG34_04450	COG2885	chlorophyll binding
IAG34_04455	COG0210	DNA helicase
IAG34_04465	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IAG34_04480	COG0121	glutamine amidotransferase
IAG34_04500	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IAG34_04505	COG0735	belongs to the Fur family
IAG34_04530	COG0420	3'-5' exonuclease activity
IAG34_04550	COG1090	epimerase
IAG34_04565	COG2050	protein possibly involved in aromatic compounds catabolism
IAG34_04575	COG2814	Major facilitator Superfamily
IAG34_04580	COG0405	Gamma-glutamyltransferase
IAG34_04670	COG0477	Major facilitator Superfamily
IAG34_04675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAG34_04700	COG0531	amino acid
IAG34_04705	COG2040	homocysteine
IAG34_04730	COG1309	transcriptional regulator
IAG34_04735	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IAG34_04740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IAG34_04750	COG1607	acyl-coa hydrolase
IAG34_04760	COG0523	cobalamin synthesis protein
IAG34_04780	COG4681	YaeQ
IAG34_04790	COG0726	polysaccharide deacetylase
IAG34_04790	COG1649	PFAM Uncharacterised BCR, COG1649
IAG34_04795	COG1215	transferase activity, transferring glycosyl groups
IAG34_04805	COG1024	Enoyl-CoA hydratase
IAG34_04820	COG1414	Transcriptional regulator
IAG34_04840	COG1028	Short-chain dehydrogenase reductase Sdr
IAG34_04850	COG0446	pyridine nucleotide-disulphide oxidoreductase
IAG34_04855	COG2271	Major facilitator Superfamily
IAG34_04865	COG2267	carboxylic ester hydrolase activity
IAG34_04870	COG1028	Short-chain dehydrogenase reductase Sdr
IAG34_04885	COG0028	Belongs to the TPP enzyme family
IAG34_04900	COG0477	Major facilitator Superfamily
IAG34_04905	COG0242	peptide deformylase activity
IAG34_04910	COG2066	Belongs to the glutaminase family
IAG34_04915	COG2207	Transcriptional regulator
IAG34_04920	COG2223	nitrite transmembrane transporter activity
IAG34_04935	COG0583	DNA-binding transcription factor activity
IAG34_04940	COG1028	Short-chain dehydrogenase reductase Sdr
IAG34_04945	COG2271	Major facilitator Superfamily
IAG34_04950	COG3959	Transketolase, thiamine diphosphate binding domain
IAG34_04955	COG3958	Transketolase
IAG34_04965	COG0306	phosphate transporter
IAG34_04985	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IAG34_05030	COG4181	ATPase activity
IAG34_05035	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IAG34_05065	COG0583	DNA-binding transcription factor activity
IAG34_05075	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAG34_05080	COG1773	rubredoxin
IAG34_05130	COG2851	Citrate transporter
IAG34_05175	COG0804	urea catabolic process
IAG34_05185	COG0830	nickel cation binding
IAG34_05200	COG0742	ribosomal rna small subunit methyltransferase
IAG34_05205	COG0768	penicillin binding
IAG34_05230	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IAG34_05235	COG2878	Part of a membrane complex involved in electron transport
IAG34_05240	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IAG34_05250	COG3384	dioxygenase
IAG34_05275	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IAG34_05315	COG0006	proline dipeptidase activity
IAG34_05320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAG34_05325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAG34_05345	COG1279	arginine transmembrane transporter activity
IAG34_05350	COG0583	DNA-binding transcription factor activity
IAG34_05390	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IAG34_05395	COG1388	LysM domain
IAG34_05395	COG0741	lytic transglycosylase activity
IAG34_05395	COG1388	LysM domain
IAG34_05395	COG0741	lytic transglycosylase activity
IAG34_05405	COG4174	ABC transporter (Permease)
IAG34_05410	COG4239	(ABC) transporter, permease
IAG34_05415	COG4172	Belongs to the ABC transporter superfamily
IAG34_05435	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IAG34_05445	COG2203	Gaf domain
IAG34_05445	COG3706	GGDEF domain
IAG34_05445	COG4251	negative regulation of phosphorylation
IAG34_05445	COG5001	Diguanylate cyclase
IAG34_05455	COG0446	pyridine nucleotide-disulphide oxidoreductase
IAG34_05455	COG1902	pentaerythritol trinitrate reductase activity
IAG34_05515	COG1113	amino acid transport
IAG34_05545	COG1012	belongs to the aldehyde dehydrogenase family
IAG34_05580	COG2072	flavoprotein involved in K transport
IAG34_05590	COG2252	PERMEase
IAG34_05595	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IAG34_05600	COG3038	cytochrome b561
IAG34_05610	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IAG34_05620	COG0527	aspartate kinase activity
IAG34_05765	COG0582	viral genome integration into host DNA
IAG34_05775	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IAG34_05785	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IAG34_05800	COG0667	Aldo Keto reductase
IAG34_05810	COG1765	OsmC-like protein
IAG34_05825	COG0542	response to heat
IAG34_05860	COG2885	chlorophyll binding
IAG34_05870	COG0625	glutathione transferase activity
IAG34_05890	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IAG34_05910	COG3634	alkyl hydroperoxide reductase activity
IAG34_05920	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IAG34_05930	COG0450	alkyl hydroperoxide reductase
IAG34_05935	COG1643	Atp-dependent helicase
IAG34_05950	COG2814	Major facilitator Superfamily
IAG34_05955	COG3135	benzoate transporter
IAG34_05960	COG1028	Short-chain dehydrogenase reductase Sdr
IAG34_05965	COG0633	Ferredoxin
IAG34_05965	COG0543	2 iron, 2 sulfur cluster binding
IAG34_05970	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IAG34_05975	COG4638	Rieske (2fe-2S)
IAG34_05980	COG0583	DNA-binding transcription factor activity
IAG34_06030	COG1570	exodeoxyribonuclease VII activity
IAG34_06065	COG1278	Cold shock
IAG34_06120	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IAG34_06130	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IAG34_06135	COG1137	ATPase activity
IAG34_06140	COG1538	Outer membrane efflux protein
IAG34_06170	COG4122	O-methyltransferase activity
IAG34_06180	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IAG34_06195	COG1522	sequence-specific DNA binding
IAG34_06210	COG1560	Kdo2-lipid A biosynthetic process
IAG34_06220	COG2814	Major facilitator Superfamily
IAG34_06245	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAG34_06280	COG0583	DNA-binding transcription factor activity
IAG34_06285	COG1914	H( )-stimulated, divalent metal cation uptake system
IAG34_06305	COG4770	biotin carboxylase activity
IAG34_06310	COG0038	chloride channel
IAG34_06325	COG1309	transcriptional regulator
IAG34_06335	COG1063	alcohol dehydrogenase
IAG34_06350	COG0439	Biotin carboxylase
IAG34_06355	COG2249	NAD(P)H dehydrogenase (quinone) activity
IAG34_06360	COG1733	regulation of RNA biosynthetic process
IAG34_06370	COG0864	Transcriptional regulator
IAG34_06385	COG1116	anion transmembrane transporter activity
IAG34_06400	COG1484	DNA-dependent DNA replication
IAG34_06405	COG4584	PFAM Integrase catalytic
IAG34_06430	COG1002	Type II restriction enzyme, methylase subunits
IAG34_06435	COG1061	Type III restriction enzyme res subunit
IAG34_06445	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IAG34_06475	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IAG34_06485	COG0789	Transcriptional regulator
IAG34_06495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAG34_06515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IAG34_06540	COG1012	belongs to the aldehyde dehydrogenase family
IAG34_06545	COG0531	amino acid
IAG34_06550	COG1760	l-serine dehydratase
IAG34_06555	COG1012	belongs to the aldehyde dehydrogenase family
IAG34_06555	COG2030	dehydratase
IAG34_06560	COG3396	Phenylacetate-CoA oxygenase
IAG34_06565	COG3460	Phenylacetate-CoA oxygenase
IAG34_06570	COG3396	Phenylacetate-CoA oxygenase
IAG34_06575	COG2151	metal-sulfur cluster biosynthetic enzyme
IAG34_06580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IAG34_06585	COG1024	Enoyl-CoA hydratase
IAG34_06590	COG1024	Enoyl-CoA hydratase
IAG34_06595	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAG34_06600	COG0183	Belongs to the thiolase family
IAG34_06605	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
IAG34_06610	COG3327	negative regulation of DNA-templated transcription, initiation
IAG34_06620	COG2050	protein possibly involved in aromatic compounds catabolism
IAG34_06635	COG0406	alpha-ribazole phosphatase activity
IAG34_06660	COG0753	catalase activity
IAG34_06665	COG3038	cytochrome b561
IAG34_06670	COG0583	DNA-binding transcription factor activity
IAG34_06680	COG1414	Transcriptional regulator
IAG34_06685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAG34_06705	COG3842	ATPase activity
IAG34_06720	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IAG34_06725	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IAG34_06730	COG2814	Major facilitator Superfamily
IAG34_06735	COG1960	acyl-CoA dehydrogenase activity
IAG34_06740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG34_06750	COG1024	Enoyl-CoA hydratase
IAG34_06760	COG2814	Major facilitator Superfamily
IAG34_06770	COG0183	Belongs to the thiolase family
IAG34_06775	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAG34_06780	COG1028	Short-chain dehydrogenase reductase Sdr
IAG34_06785	COG1024	Enoyl-CoA hydratase
IAG34_06790	COG1960	acyl-CoA dehydrogenase activity
IAG34_06795	COG2814	Major facilitator Superfamily
IAG34_06800	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IAG34_06805	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IAG34_06815	COG2814	Major facilitator Superfamily
IAG34_06825	COG1960	acyl-CoA dehydrogenase activity
IAG34_06840	COG0583	DNA-binding transcription factor activity
IAG34_06850	COG4770	biotin carboxylase activity
IAG34_06855	COG1024	Enoyl-CoA hydratase
IAG34_06860	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IAG34_06865	COG1960	acyl-CoA dehydrogenase activity
IAG34_06870	COG1309	transcriptional regulator
IAG34_06875	COG0318	PFAM AMP-dependent synthetase and ligase
IAG34_06895	COG0583	DNA-binding transcription factor activity
IAG34_06965	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IAG34_06985	COG2205	protein histidine kinase activity
IAG34_06985	COG0784	Response regulator, receiver
IAG34_07005	COG0765	amino acid transport
IAG34_07010	COG0765	amino acid transport
IAG34_07020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAG34_07025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAG34_07035	COG1280	lysine exporter protein (LysE YggA)
IAG34_07040	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IAG34_07045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IAG34_07050	COG1045	serine acetyltransferase
IAG34_07075	COG0625	glutathione transferase activity
IAG34_07080	COG0625	glutathione transferase activity
IAG34_07085	COG0583	DNA-binding transcription factor activity
IAG34_07095	COG1346	cytolysis
IAG34_07115	COG2814	Major facilitator Superfamily
IAG34_07125	COG0583	DNA-binding transcription factor activity
IAG34_07135	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
IAG34_07140	COG3052	prosthetic group binding
IAG34_07160	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IAG34_07180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAG34_07190	COG1294	oxidase, subunit
IAG34_07195	COG1271	oxidase subunit
IAG34_07215	COG0477	Major facilitator Superfamily
IAG34_07230	COG4521	taurine ABC transporter
IAG34_07235	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IAG34_07240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAG34_07245	COG2175	clavaminate synthase activity
IAG34_07255	COG1953	Uracil, thiamine, allantoin
IAG34_07270	COG0583	DNA-binding transcription factor activity
IAG34_07285	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IAG34_07300	COG0640	Transcriptional regulator
IAG34_07305	COG0798	PFAM Bile acid sodium symporter
IAG34_07310	COG0583	DNA-binding transcription factor activity
IAG34_07365	COG0436	Aminotransferase
IAG34_07375	COG0386	Belongs to the glutathione peroxidase family
IAG34_07415	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IAG34_07440	COG0012	GTP binding
IAG34_07445	COG2011	ABC-type metal ion transport system permease component
IAG34_07450	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IAG34_07460	COG1464	Belongs to the NlpA lipoprotein family
IAG34_07490	COG0765	amino acid transport
IAG34_07495	COG0765	amino acid transport
IAG34_07500	COG1126	abc transporter atp-binding protein
IAG34_07510	COG1522	sequence-specific DNA binding
IAG34_07545	COG0583	DNA-binding transcription factor activity
IAG34_07555	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IAG34_07565	COG0697	spore germination
IAG34_07600	COG3539	Fimbrial protein
IAG34_07630	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IAG34_07630	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IAG34_07680	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IAG34_07690	COG2353	YceI-like domain
IAG34_07700	COG3698	Phosphodiester glycosidase
IAG34_07715	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IAG34_07720	COG0506	proline dehydrogenase activity
IAG34_07720	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IAG34_07720	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IAG34_07730	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IAG34_07735	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IAG34_07755	COG1132	(ABC) transporter
IAG34_07760	COG3122	Protein conserved in bacteria
IAG34_07765	COG3619	membrane
IAG34_07775	COG0640	Transcriptional regulator
IAG34_07785	COG2850	peptidyl-arginine hydroxylation
IAG34_07790	COG0424	maF-like protein
IAG34_07810	COG0191	fructose-bisphosphate aldolase activity
IAG34_07815	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IAG34_07830	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IAG34_07840	COG1192	Involved in chromosome partitioning
IAG34_07845	COG1475	DNA binding
IAG34_07850	COG0811	peptide transport
IAG34_07860	COG1132	(ABC) transporter
IAG34_07865	COG1663	tetraacyldisaccharide 4'-kinase activity
IAG34_07885	COG0084	hydrolase, TatD family'
IAG34_07955	COG0776	regulation of translation
IAG34_07985	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IAG34_08055	COG0305	Participates in initiation and elongation during chromosome replication
IAG34_08140	COG4695	Portal protein
IAG34_08205	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IAG34_08255	COG0339	signal peptide processing
IAG34_08265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG34_08300	COG0702	epimerase
IAG34_08305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IAG34_08325	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IAG34_08355	COG0316	Belongs to the HesB IscA family
IAG34_08360	COG0822	iron-sulfur transferase activity
IAG34_08385	COG0776	regulation of translation
IAG34_08390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IAG34_08400	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IAG34_08410	COG1960	acyl-CoA dehydrogenase activity
IAG34_08415	COG1960	acyl-CoA dehydrogenase activity
IAG34_08435	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IAG34_08455	COG4264	IucA IucC family
IAG34_08460	COG4264	IucA IucC family
IAG34_08470	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IAG34_08500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IAG34_08520	COG0406	alpha-ribazole phosphatase activity
IAG34_08535	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IAG34_08540	COG0730	response to heat
IAG34_08560	COG4773	Receptor
IAG34_08565	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IAG34_08580	COG1131	(ABC) transporter
IAG34_08585	COG0842	Transport permease protein
IAG34_08590	COG0842	Transport permease protein
IAG34_08645	COG2226	methyltransferase
IAG34_08675	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IAG34_08710	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IAG34_08720	COG0133	tryptophan synthase activity
IAG34_08735	COG3706	GGDEF domain
IAG34_08750	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IAG34_08755	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IAG34_08760	COG0022	dehydrogenase e1 component
IAG34_08765	COG0508	dehydrogenase complex catalyzes the overall conversion of
IAG34_08770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IAG34_08780	COG1063	alcohol dehydrogenase
IAG34_08785	COG3781	membrane
IAG34_08795	COG3453	Protein conserved in bacteria
IAG34_08795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAG34_08805	COG0730	response to heat
IAG34_08820	COG2207	Transcriptional regulator
IAG34_08820	COG3708	Transcriptional regulator
IAG34_08825	COG1733	regulation of RNA biosynthetic process
IAG34_08830	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IAG34_08840	COG2188	Transcriptional regulator
IAG34_08855	COG4521	taurine ABC transporter
IAG34_08860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAG34_08880	COG0477	Major facilitator Superfamily
IAG34_08890	COG1027	Aspartate ammonia-lyase
IAG34_08905	COG0583	DNA-binding transcription factor activity
IAG34_08910	COG0583	DNA-binding transcription factor activity
IAG34_08915	COG0183	Belongs to the thiolase family
IAG34_08920	COG2031	fatty acid transporter
IAG34_08935	COG0583	DNA-binding transcription factor activity
IAG34_08970	COG2207	Transcriptional regulator
IAG34_08985	COG1028	Short-chain dehydrogenase reductase Sdr
IAG34_08995	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IAG34_09010	COG0543	2 iron, 2 sulfur cluster binding
IAG34_09010	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IAG34_09015	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IAG34_09020	COG4638	Rieske (2fe-2S)
IAG34_09030	COG0725	ABC transporter, periplasmic molybdate-binding protein
IAG34_09035	COG4149	molybdate abc transporter
IAG34_09040	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IAG34_09045	COG1028	Short-chain dehydrogenase reductase Sdr
IAG34_09050	COG1535	isochorismatase
IAG34_09050	COG3433	isochorismatase activity
IAG34_09115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAG34_09135	COG0753	catalase activity
IAG34_09145	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IAG34_09170	COG3539	Fimbrial protein
IAG34_09225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IAG34_09260	COG2207	Transcriptional regulator
IAG34_09300	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IAG34_09330	COG1120	ATPase activity
IAG34_09335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAG34_09355	COG1064	alcohol dehydrogenase
IAG34_09360	COG2207	Transcriptional regulator
IAG34_09365	COG2084	Dehydrogenase
IAG34_09375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IAG34_09380	COG0583	DNA-binding transcription factor activity
IAG34_09390	COG0129	dihydroxy-acid dehydratase activity
IAG34_09395	COG1012	belongs to the aldehyde dehydrogenase family
IAG34_09420	COG1566	PFAM secretion protein HlyD family protein
IAG34_09430	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IAG34_09460	COG0583	DNA-binding transcription factor activity
IAG34_09475	COG2188	Transcriptional regulator
IAG34_09525	COG1960	acyl-CoA dehydrogenase activity
IAG34_09535	COG1028	Short-chain dehydrogenase reductase Sdr
IAG34_09540	COG1028	Short-chain dehydrogenase reductase Sdr
IAG34_09545	COG1028	Short-chain dehydrogenase reductase Sdr
IAG34_09550	COG0583	DNA-binding transcription factor activity
IAG34_09555	COG1309	transcriptional regulator
IAG34_09595	COG0446	pyridine nucleotide-disulphide oxidoreductase
IAG34_09595	COG1902	pentaerythritol trinitrate reductase activity
IAG34_09610	COG1012	belongs to the aldehyde dehydrogenase family
IAG34_09630	COG2186	Transcriptional regulator
IAG34_09650	COG1012	belongs to the aldehyde dehydrogenase family
IAG34_09660	COG3733	amine oxidase
IAG34_09670	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IAG34_09680	COG1028	Short-chain dehydrogenase reductase Sdr
IAG34_09690	COG4638	Rieske (2fe-2S)
IAG34_09710	COG0154	amidase activity
IAG34_09720	COG2814	Major facilitator Superfamily
IAG34_09745	COG1960	acyl-CoA dehydrogenase activity
IAG34_09750	COG0583	DNA-binding transcription factor activity
IAG34_09755	COG1414	Transcriptional regulator
IAG34_09770	COG2391	methyltransferase activity
IAG34_09780	COG4993	Dehydrogenase
IAG34_09785	COG3659	wide pore channel activity
IAG34_09790	COG3420	alginic acid biosynthetic process
IAG34_09795	COG0710	3-dehydroquinate dehydratase activity
IAG34_09800	COG3485	protocatechuate 3,4-dioxygenase
IAG34_09805	COG3485	protocatechuate 3,4-dioxygenase
IAG34_09810	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IAG34_09815	COG2271	Major facilitator Superfamily
IAG34_09820	COG0596	Alpha beta hydrolase
IAG34_09825	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IAG34_09830	COG0183	Belongs to the thiolase family
IAG34_09835	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IAG34_09840	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IAG34_09850	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IAG34_09855	COG2323	membrane
IAG34_09900	COG0446	pyridine nucleotide-disulphide oxidoreductase
IAG34_09900	COG1902	pentaerythritol trinitrate reductase activity
IAG34_09925	COG0542	response to heat
IAG34_09930	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IAG34_09960	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IAG34_09965	COG0569	domain protein
IAG34_09970	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IAG34_09985	COG4774	siderophore transport
IAG34_09990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAG34_10000	COG1585	Membrane protein implicated in regulation of membrane protease activity
IAG34_10020	COG1294	oxidase, subunit
IAG34_10025	COG4890	Cyd operon protein YbgT
IAG34_10040	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
IAG34_10050	COG0552	protein localization to endoplasmic reticulum
IAG34_10075	COG0517	IMP dehydrogenase activity
IAG34_10075	COG0516	GMP reductase activity
IAG34_10080	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IAG34_10085	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IAG34_10095	COG0583	DNA-binding transcription factor activity
IAG34_10100	COG0024	Methionine aminopeptidase
IAG34_10130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAG34_10130	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IAG34_10135	COG1105	Belongs to the carbohydrate kinase PfkB family
IAG34_10140	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAG34_10140	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAG34_10140	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IAG34_10235	COG2135	peptidase activity
IAG34_10270	COG1011	Hydrolase
IAG34_10275	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IAG34_10285	COG2137	regulation of response to DNA damage stimulus
IAG34_10300	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IAG34_10320	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IAG34_10335	COG0575	Belongs to the CDS family
IAG34_10340	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IAG34_10360	COG3852	Histidine kinase
IAG34_10365	COG2204	response regulator
IAG34_10400	COG2801	Transposase and inactivated derivatives
IAG34_10430	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IAG34_10435	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IAG34_10455	COG0697	spore germination
IAG34_10460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAG34_10470	COG0303	'Molybdopterin
IAG34_10475	COG0315	cyclic pyranopterin monophosphate synthase activity
IAG34_10475	COG0521	Mo-molybdopterin cofactor biosynthetic process
IAG34_10490	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IAG34_10495	COG0243	molybdopterin cofactor binding
IAG34_10505	COG0243	molybdopterin cofactor binding
IAG34_10510	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAG34_10515	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAG34_10515	COG2146	nitrite reductase [NAD(P)H] activity
IAG34_10525	COG0745	RESPONSE REGULATOR receiver
IAG34_10530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IAG34_10530	COG1116	anion transmembrane transporter activity
IAG34_10550	COG0511	ligase activity, forming carbon-carbon bonds
IAG34_10565	COG2814	Major facilitator Superfamily
IAG34_10805	COG0069	glutamate synthase activity
IAG34_10825	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IAG34_10835	COG1454	alcohol dehydrogenase
IAG34_10840	COG0824	Thioesterase
IAG34_10850	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IAG34_10865	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IAG34_10870	COG2030	dehydratase
IAG34_10880	COG0183	Belongs to the thiolase family
IAG34_10890	COG0583	DNA-binding transcription factor activity
IAG34_10895	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IAG34_10905	COG1522	sequence-specific DNA binding
IAG34_10910	COG3135	benzoate transporter
IAG34_10940	COG0589	response to stress
IAG34_10945	COG0488	(ABC) transporter
IAG34_10965	COG4773	Receptor
IAG34_11015	COG1309	transcriptional regulator
IAG34_11025	COG0668	transmembrane transport
IAG34_11040	COG1605	Chorismate mutase
IAG34_11075	COG0308	aminopeptidase N
IAG34_11100	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IAG34_11105	COG1454	alcohol dehydrogenase
IAG34_11125	COG0531	amino acid
IAG34_11130	COG4303	Ethanolamine ammonia lyase large subunit
IAG34_11135	COG4302	ethanolamine ammonia-lyase activity
IAG34_11140	COG0519	Catalyzes the synthesis of GMP from XMP
IAG34_11140	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IAG34_11150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IAG34_11160	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IAG34_11175	COG0697	spore germination
IAG34_11180	COG1923	regulation of RNA biosynthetic process
IAG34_11190	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IAG34_11195	COG0802	atpase or kinase
IAG34_11215	COG1187	pseudouridine synthase activity
IAG34_11230	COG0583	DNA-binding transcription factor activity
IAG34_11250	COG2814	Major facilitator Superfamily
IAG34_11255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IAG34_11285	COG0729	surface antigen
IAG34_11290	COG0477	Major facilitator Superfamily
IAG34_11305	COG0174	glutamine synthetase
IAG34_11310	COG0745	RESPONSE REGULATOR receiver
IAG34_11315	COG2205	protein histidine kinase activity
IAG34_11325	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IAG34_11330	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IAG34_11355	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IAG34_11360	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IAG34_11365	COG1960	acyl-CoA dehydrogenase activity
IAG34_11395	COG0583	DNA-binding transcription factor activity
IAG34_11410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAG34_11420	COG3658	cytochrome
IAG34_11425	COG1215	transferase activity, transferring glycosyl groups
IAG34_11430	COG1649	PFAM Uncharacterised BCR, COG1649
IAG34_11430	COG0726	polysaccharide deacetylase
IAG34_11455	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IAG34_11460	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IAG34_11470	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IAG34_11495	COG0305	Participates in initiation and elongation during chromosome replication
IAG34_11500	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IAG34_11510	COG1305	Transglutaminase-like
IAG34_11520	COG2308	Evidence 4 Homologs of previously reported genes of
IAG34_11550	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IAG34_11555	COG0138	bifunctional purine biosynthesis protein purh
IAG34_11560	COG0151	Belongs to the GarS family
IAG34_11565	COG1464	Belongs to the NlpA lipoprotein family
IAG34_11570	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IAG34_11575	COG2011	ABC-type metal ion transport system permease component
IAG34_11580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAG34_11590	COG1301	dicarboxylic acid transport
IAG34_11625	COG1794	racemase activity, acting on amino acids and derivatives
IAG34_11630	COG0492	ferredoxin-NADP+ reductase activity
IAG34_11630	COG3118	belongs to the thioredoxin family
IAG34_11645	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IAG34_11645	COG3008	intermembrane lipid transfer
IAG34_11650	COG2995	paraquat-inducible protein a
IAG34_11675	COG0477	Major facilitator Superfamily
IAG34_11725	COG2186	Transcriptional regulator
IAG34_11735	COG0786	glutamate:sodium symporter activity
IAG34_11740	COG3243	poly(R)-hydroxyalkanoic acid synthase
IAG34_11765	COG3111	PFAM Bacterial OB fold (BOF) protein
IAG34_11835	COG2815	serine threonine protein kinase
IAG34_11835	COG0515	serine threonine protein kinase
IAG34_11865	COG1610	YqeY-like protein
IAG34_11870	COG4783	chaperone-mediated protein folding
IAG34_11895	COG1286	toxin biosynthetic process
IAG34_11925	COG0778	Nitroreductase
IAG34_11935	COG0513	Belongs to the DEAD box helicase family
IAG34_11955	COG2363	Small membrane protein
IAG34_11985	COG4650	regulator
IAG34_11990	COG1234	tRNA 3'-trailer cleavage
IAG34_11995	COG1690	Belongs to the RtcB family
IAG34_12015	COG2195	Cleaves the N-terminal amino acid of tripeptides
IAG34_12025	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IAG34_12035	COG2819	hydrolase of the alpha beta superfamily
IAG34_12045	COG1301	dicarboxylic acid transport
IAG34_12055	COG3139	Protein of unknown function (DUF1315)
IAG34_12060	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IAG34_12065	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IAG34_12075	COG0494	nUDIX hydrolase
IAG34_12085	COG0642	Histidine kinase
IAG34_12100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IAG34_12110	COG1720	tRNA m6t6A37 methyltransferase activity
IAG34_12125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAG34_12130	COG0826	peptidase U32
IAG34_12135	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IAG34_12145	COG4598	ABC transporter
IAG34_12150	COG4160	amino acid transport
IAG34_12155	COG4215	(ABC) transporter
IAG34_12170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAG34_12215	COG1131	(ABC) transporter
IAG34_12220	COG0842	Transport permease protein
IAG34_12235	COG0772	Belongs to the SEDS family
IAG34_12240	COG2951	lytic endotransglycosylase activity
IAG34_12265	COG2207	Transcriptional regulator
IAG34_12280	COG0052	Belongs to the universal ribosomal protein uS2 family
IAG34_12285	COG0024	Methionine aminopeptidase
IAG34_12295	COG2223	nitrite transmembrane transporter activity
IAG34_12305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IAG34_12310	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IAG34_12315	COG1960	acyl-CoA dehydrogenase activity
IAG34_12330	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IAG34_12335	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IAG34_12340	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IAG34_12360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAG34_12365	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IAG34_12370	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IAG34_12405	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IAG34_12415	COG0174	glutamine synthetase
IAG34_12430	COG0512	Glutamine amidotransferase of anthranilate synthase
IAG34_12465	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IAG34_12480	COG0302	gtp cyclohydrolase
IAG34_12500	COG3739	integral membrane protein
IAG34_12525	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
IAG34_12530	COG1132	(ABC) transporter
IAG34_12535	COG1132	(ABC) transporter
IAG34_12545	COG3433	isochorismatase activity
IAG34_12545	COG1535	isochorismatase
IAG34_12550	COG1021	2,3-dihydroxybenzoate-AMP ligase
IAG34_12555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAG34_12565	COG4774	siderophore transport
IAG34_12570	COG4607	ABC-type enterochelin transport system periplasmic component
IAG34_12575	COG4604	ABC transporter, ATP-binding protein
IAG34_12580	COG4605	iron ion homeostasis
IAG34_12585	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAG34_12590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAG34_12605	COG2964	Protein conserved in bacteria
IAG34_12620	COG1741	Belongs to the pirin family
IAG34_12710	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
IAG34_12770	COG4695	Portal protein
IAG34_12775	COG1802	Transcriptional regulator
IAG34_12775	COG4626	Terminase
IAG34_12885	COG2879	small protein
IAG34_12890	COG1966	Carbon starvation protein
IAG34_12910	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IAG34_12935	COG1067	ATP-dependent peptidase activity
IAG34_12940	COG0583	DNA-binding transcription factor activity
IAG34_12965	COG1686	Belongs to the peptidase S11 family
IAG34_12970	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IAG34_13005	COG0616	signal peptide processing
IAG34_13010	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IAG34_13020	COG0573	inorganic phosphate transmembrane transporter activity
IAG34_13025	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IAG34_13030	COG1113	amino acid transport
IAG34_13035	COG3961	Belongs to the TPP enzyme family
IAG34_13040	COG1522	sequence-specific DNA binding
IAG34_13050	COG0076	glutamate decarboxylase activity
IAG34_13055	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IAG34_13070	COG2249	NAD(P)H dehydrogenase (quinone) activity
IAG34_13080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IAG34_13115	COG0352	thiamine-phosphate diphosphorylase activity
IAG34_13140	COG0612	Peptidase, M16
IAG34_13150	COG1823	symporter activity
IAG34_13155	COG0583	DNA-binding transcription factor activity
IAG34_13160	COG0477	Major facilitator Superfamily
IAG34_13185	COG0582	viral genome integration into host DNA
IAG34_13480	COG1187	pseudouridine synthase activity
IAG34_13495	COG1686	Belongs to the peptidase S11 family
IAG34_13500	COG1252	NADH dehydrogenase
IAG34_13510	COG0415	Belongs to the DNA photolyase family
IAG34_13530	COG1215	transferase activity, transferring glycosyl groups
IAG34_13560	COG2070	2-Nitropropane dioxygenase
IAG34_13615	COG0556	nucleotide-excision repair
IAG34_13635	COG0436	Aminotransferase
IAG34_13670	COG4221	oxidoreductase activity
IAG34_13680	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IAG34_13685	COG1381	Involved in DNA repair and RecF pathway recombination
IAG34_13695	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IAG34_13710	COG0681	Belongs to the peptidase S26 family
IAG34_13720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAG34_13730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAG34_13750	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IAG34_13755	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IAG34_13760	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IAG34_13770	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IAG34_13775	COG4208	sulfate ABC transporter
IAG34_13780	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IAG34_13785	COG0583	DNA-binding transcription factor activity
IAG34_13790	COG4625	pathogenesis
IAG34_13805	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IAG34_13820	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IAG34_13830	COG1051	belongs to the nudix hydrolase family
IAG34_13830	COG1056	cytidyltransferase-related domain
IAG34_13835	COG1024	Enoyl-CoA hydratase
IAG34_13840	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IAG34_13845	COG2814	Major facilitator Superfamily
IAG34_13850	COG0047	phosphoribosylformylglycinamidine synthase activity
IAG34_13850	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IAG34_13875	COG0824	Thioesterase
IAG34_13895	COG0823	Involved in the tonB-independent uptake of proteins
IAG34_13915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IAG34_13950	COG0628	permease
IAG34_13960	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IAG34_13965	COG0596	Alpha beta hydrolase
IAG34_13970	COG0616	signal peptide processing
IAG34_13970	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IAG34_13980	COG2333	competence protein COMEC
IAG34_13980	COG0658	competence protein
IAG34_13985	COG1136	(ABC) transporter
IAG34_13990	COG4591	ABC-type transport system involved in lipoprotein release permease component
IAG34_14020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAG34_14040	COG0463	Glycosyl transferase, family 2
IAG34_14070	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IAG34_14075	COG1280	lysine exporter protein (LysE YggA)
IAG34_14095	COG0019	diaminopimelate decarboxylase activity
IAG34_14105	COG1113	amino acid transport
IAG34_14120	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IAG34_14130	COG3339	Conserved Protein
IAG34_14135	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IAG34_14140	COG0243	molybdopterin cofactor binding
IAG34_14145	COG1929	Belongs to the glycerate kinase type-1 family
IAG34_14160	COG0778	Nitroreductase
IAG34_14180	COG3811	Belongs to the UPF0386 family
IAG34_14190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAG34_14205	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IAG34_14225	COG0741	lytic transglycosylase activity
IAG34_14245	COG0584	glycerophosphoryl diester phosphodiesterase
IAG34_14250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAG34_14270	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IAG34_14290	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IAG34_14295	COG0477	Major facilitator Superfamily
IAG34_14345	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IAG34_14350	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IAG34_14375	COG0505	Belongs to the CarA family
IAG34_14390	COG1309	transcriptional regulator
IAG34_14395	COG0251	oxidation-reduction process
IAG34_14405	COG0589	response to stress
IAG34_14420	COG2843	Capsule synthesis protein
IAG34_14440	COG2321	neutral zinc metallopeptidase
IAG34_14445	COG2354	Protein conserved in bacteria
IAG34_14465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IAG34_14490	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IAG34_14495	COG1053	succinate dehydrogenase
IAG34_14500	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IAG34_14505	COG2009	succinate dehydrogenase
IAG34_14545	COG2921	Belongs to the UPF0250 family
IAG34_14550	COG0321	lipoyl(octanoyl) transferase activity
IAG34_14565	COG0531	amino acid
IAG34_14575	COG1733	regulation of RNA biosynthetic process
IAG34_14580	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IAG34_14585	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IAG34_14585	COG1648	precorrin-2 dehydrogenase activity
IAG34_14600	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IAG34_14630	COG0671	phosphoesterase, PA-phosphatase related
IAG34_14635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAG34_14645	COG1538	Outer membrane efflux protein
IAG34_14650	COG0393	Putative heavy-metal-binding
IAG34_14655	COG0393	Putative heavy-metal-binding
IAG34_14665	COG1028	Short-chain dehydrogenase reductase Sdr
IAG34_14675	COG0525	valine-tRNA ligase activity
IAG34_14695	COG0583	DNA-binding transcription factor activity
IAG34_14700	COG0004	ammonium transporteR
IAG34_14710	COG0642	Histidine kinase
IAG34_14715	COG0745	RESPONSE REGULATOR receiver
IAG34_14720	COG2194	sulfuric ester hydrolase activity
IAG34_14740	COG1752	Esterase of the alpha-beta hydrolase superfamily
IAG34_14760	COG0142	geranyltranstransferase activity
IAG34_14765	COG2828	Protein conserved in bacteria
IAG34_14770	COG1113	amino acid transport
IAG34_14790	COG2207	Transcriptional regulator
IAG34_14815	COG2249	NAD(P)H dehydrogenase (quinone) activity
IAG34_14825	COG0560	Phosphoserine phosphatase
IAG34_14835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAG34_14845	COG1530	ribonuclease E activity
IAG34_14850	COG0424	maF-like protein
IAG34_14855	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IAG34_14860	COG1792	Involved in formation and maintenance of cell shape
IAG34_14865	COG1077	Cell shape determining protein MreB Mrl
IAG34_14870	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IAG34_14880	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IAG34_14910	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IAG34_14915	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IAG34_14920	COG1752	Esterase of the alpha-beta hydrolase superfamily
IAG34_14925	COG1115	amino acid carrier protein
IAG34_14945	COG2814	Major facilitator Superfamily
IAG34_14950	COG1289	transmembrane transporter activity
IAG34_14960	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IAG34_15000	COG1376	ErfK ybiS ycfS ynhG family protein
IAG34_15005	COG2832	Protein of unknown function (DUF454)
IAG34_15015	COG5510	response to toxic substance
IAG34_15035	COG0840	transmembrane signaling receptor activity
IAG34_15075	COG3422	double-strand break repair
IAG34_15080	COG2824	Alkylphosphonate utilization operon protein PhnA
IAG34_15085	COG3189	MarR family transcriptional regulator
IAG34_15090	COG0596	Alpha beta hydrolase
IAG34_15095	COG0778	Nitroreductase
IAG34_15100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAG34_15105	COG1335	isochorismatase
IAG34_15110	COG0251	oxidation-reduction process
IAG34_15115	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IAG34_15120	COG2233	PERMEase
IAG34_15135	COG0354	folic acid binding
IAG34_15140	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IAG34_15150	COG0679	Auxin Efflux Carrier
IAG34_15155	COG1902	pentaerythritol trinitrate reductase activity
IAG34_15160	COG4772	TonB-dependent receptor
IAG34_15165	COG2094	Belongs to the DNA glycosylase MPG family
IAG34_15190	COG1217	gtp-binding protein TYPA
IAG34_15195	COG2233	PERMEase
IAG34_15205	COG0833	amino acid
IAG34_15210	COG1690	Belongs to the RtcB family
IAG34_15220	COG2885	chlorophyll binding
IAG34_15220	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IAG34_15230	COG0183	Belongs to the thiolase family
IAG34_15250	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAG34_15270	COG2207	Transcriptional regulator
IAG34_15275	COG0183	Belongs to the thiolase family
IAG34_15295	COG2153	protein acetylation
IAG34_15305	COG1272	protein, Hemolysin III
IAG34_15325	COG0450	alkyl hydroperoxide reductase
IAG34_15345	COG0285	dihydrofolate synthase activity
IAG34_15390	COG4206	TonB-dependent receptor
IAG34_15395	COG2096	Adenosyltransferase
IAG34_15400	COG0584	glycerophosphoryl diester phosphodiesterase
IAG34_15415	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IAG34_15420	COG0745	RESPONSE REGULATOR receiver
IAG34_15425	COG2205	protein histidine kinase activity
IAG34_15435	COG1960	acyl-CoA dehydrogenase activity
IAG34_15440	COG1960	acyl-CoA dehydrogenase activity
IAG34_15495	COG1215	transferase activity, transferring glycosyl groups
IAG34_15510	COG1091	dTDP-4-dehydrorhamnose reductase activity
IAG34_15525	COG0438	transferase activity, transferring glycosyl groups
IAG34_15530	COG0726	polysaccharide deacetylase
IAG34_15545	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IAG34_15550	COG2205	protein histidine kinase activity
IAG34_15555	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IAG34_15560	COG2865	translation initiation factor activity
IAG34_15570	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IAG34_15605	COG0582	viral genome integration into host DNA
IAG34_15635	COG1862	Preprotein translocase
IAG34_15645	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IAG34_15650	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IAG34_15660	COG3781	membrane
IAG34_15665	COG0613	PHP domain protein
IAG34_15675	COG2350	Protein conserved in bacteria
IAG34_15705	COG1607	acyl-coa hydrolase
IAG34_15765	COG2199	diguanylate cyclase activity
IAG34_15775	COG1408	metallophosphoesterase
IAG34_15780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAG34_15790	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IAG34_15810	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IAG34_15815	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IAG34_15830	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IAG34_15840	COG2969	positive regulation of protein catabolic process
IAG34_15860	COG1960	acyl-CoA dehydrogenase activity
IAG34_15880	COG1309	transcriptional regulator
IAG34_15885	COG1960	acyl-CoA dehydrogenase activity
IAG34_15940	COG1183	phosphatidylcholine synthase activity
IAG34_15945	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IAG34_15975	COG1196	nuclear chromosome segregation
IAG34_15975	COG0741	lytic transglycosylase activity
IAG34_15975	COG0739	heme binding
IAG34_15985	COG1702	phosphate starvation-inducible protein PhoH
IAG34_16020	COG1295	ribonuclease BN
IAG34_16025	COG0697	spore germination
IAG34_16030	COG2169	Transcriptional regulator
IAG34_16035	COG0179	Fumarylacetoacetate (FAA) hydrolase
IAG34_16080	COG0557	exoribonuclease II activity
IAG34_16085	COG0339	signal peptide processing
IAG34_16090	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IAG34_16130	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IAG34_16135	COG1960	acyl-CoA dehydrogenase activity
IAG34_16290	COG0626	cystathionine gamma-synthase activity
IAG34_16295	COG0433	COG0433 Predicted ATPase
IAG34_16300	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IAG34_16300	COG1017	nitric oxide dioxygenase activity
IAG34_16305	COG1959	2 iron, 2 sulfur cluster binding
IAG34_16320	COG1301	dicarboxylic acid transport
IAG34_16325	COG1946	Acyl-CoA thioesterase
IAG34_16345	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IAG34_16350	COG1040	competence protein
IAG34_16355	COG0494	nUDIX hydrolase
IAG34_16365	COG0598	Magnesium transport protein CorA
IAG34_16375	COG2854	intermembrane phospholipid transfer
IAG34_16385	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IAG34_16390	COG1127	ABC transporter
IAG34_16400	COG0513	Belongs to the DEAD box helicase family
IAG34_16420	COG0408	coproporphyrinogen oxidase activity
IAG34_16435	COG1960	acyl-CoA dehydrogenase activity
IAG34_16445	COG1983	PspC domain protein
IAG34_16450	COG0517	IMP dehydrogenase activity
IAG34_16510	COG0583	DNA-binding transcription factor activity
IAG34_16550	COG1012	belongs to the aldehyde dehydrogenase family
IAG34_16560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IAG34_16565	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IAG34_16570	COG0833	amino acid
IAG34_16600	COG1192	Involved in chromosome partitioning
IAG34_16605	COG0628	permease
IAG34_16615	COG1289	transmembrane transporter activity
IAG34_16630	COG2249	NAD(P)H dehydrogenase (quinone) activity
IAG34_16635	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IAG34_16645	COG0277	FAD linked oxidase domain protein
IAG34_16650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IAG34_16675	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IAG34_16680	COG5380	lipid catabolic process
IAG34_16700	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IAG34_16750	COG0194	GDP metabolic process
IAG34_16765	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IAG34_16785	COG3307	-O-antigen
IAG34_16805	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IAG34_16810	COG1704	LemA family
IAG34_16820	COG0493	'glutamate synthase
IAG34_16825	COG0070	glutamate synthase
IAG34_16825	COG0069	glutamate synthase activity
IAG34_16825	COG0067	glutamate synthase
IAG34_16875	COG2226	methyltransferase
IAG34_16890	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IAG34_16895	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IAG34_16940	COG0833	amino acid
IAG34_17025	COG0488	(ABC) transporter
IAG34_17035	COG4221	oxidoreductase activity
IAG34_17040	COG0659	secondary active sulfate transmembrane transporter activity
IAG34_17075	COG0427	acetyl-CoA hydrolase
IAG34_17105	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IAG34_17135	COG2329	Antibiotic biosynthesis monooxygenase
IAG34_17150	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IAG34_17200	COG3335	DDE superfamily endonuclease
IAG34_17245	COG0667	Aldo Keto reductase
IAG34_17265	COG0583	DNA-binding transcription factor activity
IAG34_17270	COG2814	Major facilitator Superfamily
IAG34_17300	COG1335	isochorismatase
IAG34_17310	COG1012	belongs to the aldehyde dehydrogenase family
IAG34_17315	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IAG34_17325	COG1113	amino acid transport
IAG34_17335	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IAG34_17350	COG2814	Major facilitator Superfamily
IAG34_17360	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IAG34_17360	COG0352	thiamine-phosphate diphosphorylase activity
IAG34_17360	COG0351	phosphomethylpyrimidine kinase
IAG34_17380	COG1309	transcriptional regulator
IAG34_17400	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IAG34_17410	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IAG34_17415	COG3162	membrane
IAG34_17420	COG2205	protein histidine kinase activity
IAG34_17420	COG2198	Histidine kinase
IAG34_17420	COG0784	Response regulator, receiver
IAG34_17450	COG1335	isochorismatase
IAG34_17455	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IAG34_17465	COG0668	transmembrane transport
IAG34_17470	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IAG34_17475	COG1519	Transferase
IAG34_17480	COG1902	pentaerythritol trinitrate reductase activity
IAG34_17500	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IAG34_17525	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IAG34_17525	COG0426	domain, Protein
IAG34_17530	COG4774	siderophore transport
IAG34_17535	COG2119	membrane
IAG34_17545	COG0508	dehydrogenase complex catalyzes the overall conversion of
IAG34_17555	COG4942	peptidase
IAG34_17570	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IAG34_17580	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IAG34_17600	COG0189	ligase activity
IAG34_17620	COG0708	Exodeoxyribonuclease III
IAG34_17625	COG1393	Belongs to the ArsC family
IAG34_17640	COG3706	GGDEF domain
IAG34_17675	COG2351	hydroxyisourate hydrolase activity
IAG34_17680	COG2233	PERMEase
IAG34_17690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAG34_17700	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
IAG34_17710	COG3150	esterase
IAG34_17740	COG2918	glutathione biosynthetic process
IAG34_17755	COG2733	membrane
IAG34_17760	COG0436	Aminotransferase
IAG34_17765	COG0534	Mate efflux family protein
IAG34_17850	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IAG34_17855	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IAG34_17865	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IAG34_17920	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IAG34_17925	COG0546	phosphoglycolate phosphatase activity
IAG34_17935	COG0010	Belongs to the arginase family
IAG34_17965	COG2188	Transcriptional regulator
IAG34_17975	COG0523	cobalamin synthesis protein
IAG34_17985	COG1113	amino acid transport
IAG34_17995	COG0625	glutathione transferase activity
IAG34_18010	COG3328	transposase activity
IAG34_18020	COG1683	Conserved Protein
IAG34_18025	COG0534	Mate efflux family protein
IAG34_18030	COG0385	Bile acid
IAG34_18035	COG1335	isochorismatase
IAG34_18040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAG34_18060	COG2116	formate transmembrane transporter activity
IAG34_18065	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IAG34_18070	COG2133	pyrroloquinoline quinone binding
IAG34_18075	COG2983	Belongs to the UPF0260 family
IAG34_18095	COG1194	a g-specific adenine glycosylase
IAG34_18110	COG2818	Glycosylase
IAG34_18115	COG1064	alcohol dehydrogenase
IAG34_18120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAG34_18135	COG0583	DNA-binding transcription factor activity
IAG34_18140	COG0656	L-ascorbic acid biosynthetic process
IAG34_18145	COG2814	Major facilitator Superfamily
IAG34_18180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAG34_18195	COG2233	PERMEase
IAG34_18205	COG0583	DNA-binding transcription factor activity
IAG34_18240	COG0733	neurotransmitter:sodium symporter activity
IAG34_18250	COG3328	transposase activity
IAG34_18285	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IAG34_18290	COG0657	acetylesterase activity
IAG34_18340	COG2951	lytic endotransglycosylase activity
IAG34_18345	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IAG34_18360	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IAG34_18380	COG0671	phosphoesterase, PA-phosphatase related
IAG34_18385	COG0861	Integral membrane protein TerC family
IAG34_18395	COG0754	glutathionylspermidine amidase activity
IAG34_18405	COG0402	S-adenosylhomocysteine deaminase activity
IAG34_18440	COG0706	membrane insertase activity
IAG34_18465	COG0592	DNA-directed DNA polymerase activity
IAG34_18475	COG0187	DNA topoisomerase II activity
IAG34_18485	COG0586	Pfam SNARE associated Golgi protein
IAG34_18490	COG0488	(ABC) transporter
IAG34_18530	COG0596	Alpha beta hydrolase
IAG34_18535	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IAG34_18540	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IAG34_18575	COG0542	response to heat
IAG34_18605	COG0501	Belongs to the peptidase M48B family
IAG34_18610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAG34_18675	COG2130	NADP-dependent
IAG34_18680	COG1309	transcriptional regulator
IAG34_18690	COG1902	pentaerythritol trinitrate reductase activity
IAG34_18700	COG1979	alcohol dehydrogenase
IAG34_18715	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IAG34_18745	COG0477	Major facilitator Superfamily
IAG34_18750	COG0697	spore germination
IAG34_18760	COG0604	alcohol dehydrogenase
IAG34_18760	COG3321	synthase
IAG34_18765	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IAG34_18810	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
IAG34_18835	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IAG34_18845	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
IAG34_18945	COG2816	NAD+ diphosphatase activity
IAG34_18950	COG3046	protein related to deoxyribodipyrimidine photolyase
IAG34_18965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAG34_18990	COG1192	Involved in chromosome partitioning
IAG34_19090	COG0589	response to stress
IAG34_19095	COG0659	secondary active sulfate transmembrane transporter activity
