locus-tag	class	description
AOT16_00010	COG0592	DNA-directed DNA polymerase activity
AOT16_00020	COG0187	DNA topoisomerase II activity
AOT16_00030	COG0586	Pfam SNARE associated Golgi protein
AOT16_00035	COG0488	(ABC) transporter
AOT16_00060	COG0596	Alpha beta hydrolase
AOT16_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AOT16_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AOT16_00125	COG0733	neurotransmitter:sodium symporter activity
AOT16_00165	COG2233	PERMEase
AOT16_00180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOT16_00215	COG2814	Major facilitator Superfamily
AOT16_00220	COG0656	L-ascorbic acid biosynthetic process
AOT16_00225	COG0583	DNA-binding transcription factor activity
AOT16_00235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOT16_00240	COG1064	alcohol dehydrogenase
AOT16_00245	COG2818	Glycosylase
AOT16_00260	COG1194	a g-specific adenine glycosylase
AOT16_00280	COG2983	Belongs to the UPF0260 family
AOT16_00285	COG2133	pyrroloquinoline quinone binding
AOT16_00290	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AOT16_00295	COG2116	formate transmembrane transporter activity
AOT16_00315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOT16_00320	COG1335	isochorismatase
AOT16_00325	COG0385	Bile acid
AOT16_00330	COG0534	Mate efflux family protein
AOT16_00335	COG1683	Conserved Protein
AOT16_00355	COG0625	glutathione transferase activity
AOT16_00365	COG1113	amino acid transport
AOT16_00375	COG0523	cobalamin synthesis protein
AOT16_00385	COG2188	Transcriptional regulator
AOT16_00415	COG0010	Belongs to the arginase family
AOT16_00430	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AOT16_00435	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AOT16_00445	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AOT16_00450	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AOT16_00550	COG0534	Mate efflux family protein
AOT16_00555	COG0436	Aminotransferase
AOT16_00560	COG2733	membrane
AOT16_00575	COG2918	glutathione biosynthetic process
AOT16_00585	COG3501	Rhs element vgr protein
AOT16_00590	COG1388	LysM domain
AOT16_00590	COG0791	NLP P60 protein
AOT16_00615	COG3150	esterase
AOT16_00625	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_00630	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AOT16_00640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOT16_00650	COG2233	PERMEase
AOT16_00655	COG2351	hydroxyisourate hydrolase activity
AOT16_00690	COG3706	GGDEF domain
AOT16_00705	COG1393	Belongs to the ArsC family
AOT16_00710	COG0708	Exodeoxyribonuclease III
AOT16_00730	COG0189	ligase activity
AOT16_00750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AOT16_00760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AOT16_00775	COG4942	peptidase
AOT16_00785	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOT16_00795	COG2119	membrane
AOT16_00815	COG4774	siderophore transport
AOT16_00820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOT16_00820	COG0426	domain, Protein
AOT16_00845	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AOT16_00865	COG1902	pentaerythritol trinitrate reductase activity
AOT16_00870	COG1519	Transferase
AOT16_00875	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AOT16_00880	COG0668	transmembrane transport
AOT16_00890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOT16_00895	COG1335	isochorismatase
AOT16_00900	COG1522	sequence-specific DNA binding
AOT16_00905	COG3328	transposase activity
AOT16_00930	COG2205	protein histidine kinase activity
AOT16_00930	COG0784	Response regulator, receiver
AOT16_00930	COG2198	Histidine kinase
AOT16_00935	COG3162	membrane
AOT16_00940	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOT16_00950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOT16_00960	COG3706	GGDEF domain
AOT16_00970	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AOT16_00975	COG1309	transcriptional regulator
AOT16_00995	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AOT16_00995	COG0352	thiamine-phosphate diphosphorylase activity
AOT16_00995	COG0351	phosphomethylpyrimidine kinase
AOT16_01005	COG2814	Major facilitator Superfamily
AOT16_01020	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AOT16_01030	COG1113	amino acid transport
AOT16_01040	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AOT16_01045	COG1012	belongs to the aldehyde dehydrogenase family
AOT16_01055	COG1335	isochorismatase
AOT16_01085	COG2814	Major facilitator Superfamily
AOT16_01090	COG0583	DNA-binding transcription factor activity
AOT16_01110	COG0667	Aldo Keto reductase
AOT16_01140	COG1733	regulation of RNA biosynthetic process
AOT16_01145	COG2249	NAD(P)H dehydrogenase (quinone) activity
AOT16_01210	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AOT16_01225	COG2329	Antibiotic biosynthesis monooxygenase
AOT16_01255	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AOT16_01285	COG0427	acetyl-CoA hydrolase
AOT16_01295	COG0745	RESPONSE REGULATOR receiver
AOT16_01305	COG0659	secondary active sulfate transmembrane transporter activity
AOT16_01310	COG4221	oxidoreductase activity
AOT16_01320	COG0488	(ABC) transporter
AOT16_01400	COG0833	amino acid
AOT16_01445	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AOT16_01450	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AOT16_01465	COG2226	methyltransferase
AOT16_01515	COG0070	glutamate synthase
AOT16_01515	COG0067	glutamate synthase
AOT16_01515	COG0069	glutamate synthase activity
AOT16_01520	COG0493	'glutamate synthase
AOT16_01530	COG1704	LemA family
AOT16_01535	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AOT16_01555	COG3307	-O-antigen
AOT16_01575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AOT16_01585	COG0194	GDP metabolic process
AOT16_01635	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AOT16_01655	COG5380	lipid catabolic process
AOT16_01660	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AOT16_01685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AOT16_01690	COG0277	FAD linked oxidase domain protein
AOT16_01700	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AOT16_01705	COG2249	NAD(P)H dehydrogenase (quinone) activity
AOT16_01720	COG1289	transmembrane transporter activity
AOT16_01730	COG0628	permease
AOT16_01735	COG1192	Involved in chromosome partitioning
AOT16_01765	COG0833	amino acid
AOT16_01770	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AOT16_01775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AOT16_01785	COG1012	belongs to the aldehyde dehydrogenase family
AOT16_01825	COG0583	DNA-binding transcription factor activity
AOT16_01870	COG0517	IMP dehydrogenase activity
AOT16_01875	COG1983	PspC domain protein
AOT16_01885	COG1960	acyl-CoA dehydrogenase activity
AOT16_01900	COG0408	coproporphyrinogen oxidase activity
AOT16_01920	COG0513	Belongs to the DEAD box helicase family
AOT16_01930	COG1127	ABC transporter
AOT16_01935	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AOT16_01945	COG2854	intermembrane phospholipid transfer
AOT16_01955	COG0598	Magnesium transport protein CorA
AOT16_01965	COG0494	nUDIX hydrolase
AOT16_01970	COG1040	competence protein
AOT16_01975	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AOT16_01995	COG1946	Acyl-CoA thioesterase
AOT16_02000	COG1301	dicarboxylic acid transport
AOT16_02015	COG1959	2 iron, 2 sulfur cluster binding
AOT16_02020	COG1017	nitric oxide dioxygenase activity
AOT16_02020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOT16_02025	COG0433	COG0433 Predicted ATPase
AOT16_02030	COG0626	cystathionine gamma-synthase activity
AOT16_02150	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AOT16_02160	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AOT16_02185	COG1960	acyl-CoA dehydrogenase activity
AOT16_02190	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AOT16_02220	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AOT16_02225	COG0339	signal peptide processing
AOT16_02230	COG0557	exoribonuclease II activity
AOT16_02275	COG0179	Fumarylacetoacetate (FAA) hydrolase
AOT16_02280	COG2169	Transcriptional regulator
AOT16_02285	COG0697	spore germination
AOT16_02290	COG1295	ribonuclease BN
AOT16_02325	COG1702	phosphate starvation-inducible protein PhoH
AOT16_02335	COG1196	nuclear chromosome segregation
AOT16_02335	COG0741	lytic transglycosylase activity
AOT16_02335	COG0739	heme binding
AOT16_02365	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AOT16_02370	COG1183	phosphatidylcholine synthase activity
AOT16_02415	COG1960	acyl-CoA dehydrogenase activity
AOT16_02420	COG1309	transcriptional regulator
AOT16_02435	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AOT16_02440	COG1960	acyl-CoA dehydrogenase activity
AOT16_02460	COG2969	positive regulation of protein catabolic process
AOT16_02470	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AOT16_02485	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AOT16_02490	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AOT16_02510	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AOT16_02520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AOT16_02525	COG1408	metallophosphoesterase
AOT16_02535	COG2199	diguanylate cyclase activity
AOT16_02580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOT16_02580	COG3453	Protein conserved in bacteria
AOT16_02595	COG1607	acyl-coa hydrolase
AOT16_02625	COG2350	Protein conserved in bacteria
AOT16_02635	COG0613	PHP domain protein
AOT16_02640	COG3781	membrane
AOT16_02650	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AOT16_02655	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AOT16_02665	COG1862	Preprotein translocase
AOT16_02710	COG2205	protein histidine kinase activity
AOT16_02715	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AOT16_02735	COG0726	polysaccharide deacetylase
AOT16_02740	COG0463	Glycosyl transferase, family 2
AOT16_02745	COG0438	transferase activity, transferring glycosyl groups
AOT16_02810	COG0625	glutathione transferase activity
AOT16_02815	COG0583	DNA-binding transcription factor activity
AOT16_02820	COG1960	acyl-CoA dehydrogenase activity
AOT16_02825	COG1960	acyl-CoA dehydrogenase activity
AOT16_02835	COG2205	protein histidine kinase activity
AOT16_02840	COG0745	RESPONSE REGULATOR receiver
AOT16_02845	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AOT16_02865	COG2096	Adenosyltransferase
AOT16_02880	COG0133	tryptophan synthase activity
AOT16_02915	COG0285	dihydrofolate synthase activity
AOT16_02935	COG0450	alkyl hydroperoxide reductase
AOT16_02950	COG0477	Major facilitator Superfamily
AOT16_02955	COG1272	protein, Hemolysin III
AOT16_02985	COG0183	Belongs to the thiolase family
AOT16_02990	COG2207	Transcriptional regulator
AOT16_03010	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOT16_03030	COG0183	Belongs to the thiolase family
AOT16_03040	COG2885	chlorophyll binding
AOT16_03040	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AOT16_03050	COG1690	Belongs to the RtcB family
AOT16_03055	COG0833	amino acid
AOT16_03065	COG2233	PERMEase
AOT16_03095	COG2094	Belongs to the DNA glycosylase MPG family
AOT16_03120	COG1902	pentaerythritol trinitrate reductase activity
AOT16_03125	COG0679	Auxin Efflux Carrier
AOT16_03135	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AOT16_03140	COG0354	folic acid binding
AOT16_03150	COG3189	MarR family transcriptional regulator
AOT16_03155	COG2824	Alkylphosphonate utilization operon protein PhnA
AOT16_03160	COG3422	double-strand break repair
AOT16_03200	COG0840	transmembrane signaling receptor activity
AOT16_03220	COG5510	response to toxic substance
AOT16_03230	COG2832	Protein of unknown function (DUF454)
AOT16_03235	COG1376	ErfK ybiS ycfS ynhG family protein
AOT16_03285	COG1289	transmembrane transporter activity
AOT16_03290	COG2814	Major facilitator Superfamily
AOT16_03305	COG1115	amino acid carrier protein
AOT16_03310	COG1752	Esterase of the alpha-beta hydrolase superfamily
AOT16_03315	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AOT16_03320	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AOT16_03350	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AOT16_03360	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AOT16_03365	COG1077	Cell shape determining protein MreB Mrl
AOT16_03370	COG1792	Involved in formation and maintenance of cell shape
AOT16_03375	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AOT16_03380	COG0424	maF-like protein
AOT16_03385	COG1530	ribonuclease E activity
AOT16_03395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOT16_03415	COG2249	NAD(P)H dehydrogenase (quinone) activity
AOT16_03440	COG2207	Transcriptional regulator
AOT16_03460	COG1113	amino acid transport
AOT16_03465	COG2828	Protein conserved in bacteria
AOT16_03470	COG0142	geranyltranstransferase activity
AOT16_03475	COG2315	Protein conserved in bacteria
AOT16_03490	COG1752	Esterase of the alpha-beta hydrolase superfamily
AOT16_03510	COG2194	sulfuric ester hydrolase activity
AOT16_03515	COG0745	RESPONSE REGULATOR receiver
AOT16_03520	COG0642	Histidine kinase
AOT16_03530	COG0004	ammonium transporteR
AOT16_03535	COG0583	DNA-binding transcription factor activity
AOT16_03555	COG0525	valine-tRNA ligase activity
AOT16_03565	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_03575	COG0393	Putative heavy-metal-binding
AOT16_03580	COG0393	Putative heavy-metal-binding
AOT16_03585	COG1538	Outer membrane efflux protein
AOT16_03595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOT16_03600	COG0671	phosphoesterase, PA-phosphatase related
AOT16_03630	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AOT16_03645	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AOT16_03645	COG1648	precorrin-2 dehydrogenase activity
AOT16_03650	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AOT16_03655	COG1733	regulation of RNA biosynthetic process
AOT16_03665	COG0531	amino acid
AOT16_03680	COG0321	lipoyl(octanoyl) transferase activity
AOT16_03685	COG2921	Belongs to the UPF0250 family
AOT16_03725	COG2009	succinate dehydrogenase
AOT16_03730	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AOT16_03735	COG1053	succinate dehydrogenase
AOT16_03740	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AOT16_03755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOT16_03775	COG2354	Protein conserved in bacteria
AOT16_03780	COG2321	neutral zinc metallopeptidase
AOT16_03805	COG2843	Capsule synthesis protein
AOT16_03820	COG0589	response to stress
AOT16_03840	COG0505	Belongs to the CarA family
AOT16_03865	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOT16_03870	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AOT16_03920	COG0477	Major facilitator Superfamily
AOT16_03925	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AOT16_03945	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AOT16_03970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOT16_03975	COG0584	glycerophosphoryl diester phosphodiesterase
AOT16_03995	COG0741	lytic transglycosylase activity
AOT16_04015	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AOT16_04030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOT16_04055	COG0778	Nitroreductase
AOT16_04070	COG1929	Belongs to the glycerate kinase type-1 family
AOT16_04075	COG0243	molybdopterin cofactor binding
AOT16_04080	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AOT16_04095	COG3339	Conserved Protein
AOT16_04105	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AOT16_04120	COG1113	amino acid transport
AOT16_04130	COG0019	diaminopimelate decarboxylase activity
AOT16_04140	COG1280	lysine exporter protein (LysE YggA)
AOT16_04145	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AOT16_04175	COG0463	Glycosyl transferase, family 2
AOT16_04195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOT16_04225	COG4591	ABC-type transport system involved in lipoprotein release permease component
AOT16_04230	COG1136	(ABC) transporter
AOT16_04235	COG2333	competence protein COMEC
AOT16_04235	COG0658	competence protein
AOT16_04245	COG0616	signal peptide processing
AOT16_04245	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AOT16_04250	COG0596	Alpha beta hydrolase
AOT16_04255	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AOT16_04265	COG0628	permease
AOT16_04300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOT16_04320	COG0823	Involved in the tonB-independent uptake of proteins
AOT16_04340	COG0824	Thioesterase
AOT16_04345	COG1473	amidohydrolase
AOT16_04365	COG0047	phosphoribosylformylglycinamidine synthase activity
AOT16_04365	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AOT16_04370	COG2814	Major facilitator Superfamily
AOT16_04380	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AOT16_04385	COG1024	Enoyl-CoA hydratase
AOT16_04390	COG1056	cytidyltransferase-related domain
AOT16_04390	COG1051	belongs to the nudix hydrolase family
AOT16_04400	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AOT16_04415	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AOT16_04430	COG4625	pathogenesis
AOT16_04435	COG0583	DNA-binding transcription factor activity
AOT16_04440	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AOT16_04445	COG4208	sulfate ABC transporter
AOT16_04450	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AOT16_04460	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AOT16_04465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AOT16_04470	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AOT16_04490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOT16_04505	COG0681	Belongs to the peptidase S26 family
AOT16_04520	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AOT16_04530	COG1381	Involved in DNA repair and RecF pathway recombination
AOT16_04535	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AOT16_04545	COG4221	oxidoreductase activity
AOT16_04590	COG0556	nucleotide-excision repair
AOT16_04645	COG2070	2-Nitropropane dioxygenase
AOT16_04675	COG1215	transferase activity, transferring glycosyl groups
AOT16_04690	COG0415	Belongs to the DNA photolyase family
AOT16_04700	COG1252	NADH dehydrogenase
AOT16_04705	COG1686	Belongs to the peptidase S11 family
AOT16_04720	COG1187	pseudouridine synthase activity
AOT16_04740	COG0477	Major facilitator Superfamily
AOT16_04745	COG0583	DNA-binding transcription factor activity
AOT16_04760	COG0612	Peptidase, M16
AOT16_04785	COG0352	thiamine-phosphate diphosphorylase activity
AOT16_04820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOT16_04835	COG1309	transcriptional regulator
AOT16_04845	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AOT16_04850	COG0076	glutamate decarboxylase activity
AOT16_04860	COG1522	sequence-specific DNA binding
AOT16_04865	COG3961	Belongs to the TPP enzyme family
AOT16_04870	COG1113	amino acid transport
AOT16_04875	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AOT16_04880	COG0573	inorganic phosphate transmembrane transporter activity
AOT16_04890	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AOT16_04895	COG0616	signal peptide processing
AOT16_04930	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AOT16_04935	COG1686	Belongs to the peptidase S11 family
AOT16_04960	COG0583	DNA-binding transcription factor activity
AOT16_04965	COG1067	ATP-dependent peptidase activity
AOT16_05010	COG1966	Carbon starvation protein
AOT16_05015	COG2879	small protein
AOT16_05045	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AOT16_05045	COG2508	Transcriptional regulator
AOT16_05065	COG1113	amino acid transport
AOT16_05070	COG0583	DNA-binding transcription factor activity
AOT16_05075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOT16_05080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOT16_05095	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOT16_05100	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AOT16_05100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOT16_05135	COG2814	Major facilitator Superfamily
AOT16_05140	COG4948	Mandelate Racemase Muconate Lactonizing
AOT16_05150	COG1309	transcriptional regulator
AOT16_05165	COG1741	Belongs to the pirin family
AOT16_05175	COG2964	Protein conserved in bacteria
AOT16_05190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOT16_05195	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOT16_05200	COG4605	iron ion homeostasis
AOT16_05205	COG4604	ABC transporter, ATP-binding protein
AOT16_05210	COG4607	ABC-type enterochelin transport system periplasmic component
AOT16_05225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOT16_05230	COG1021	2,3-dihydroxybenzoate-AMP ligase
AOT16_05235	COG1535	isochorismatase
AOT16_05235	COG3433	isochorismatase activity
AOT16_05250	COG1132	(ABC) transporter
AOT16_05260	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AOT16_05270	COG1169	isochorismate synthase
AOT16_05285	COG3739	integral membrane protein
AOT16_05340	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AOT16_05370	COG0308	aminopeptidase N
AOT16_05375	COG0512	Glutamine amidotransferase of anthranilate synthase
AOT16_05385	COG3104	oligopeptide transport
AOT16_05400	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AOT16_05435	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AOT16_05440	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AOT16_05445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOT16_05465	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AOT16_05470	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AOT16_05475	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AOT16_05490	COG1960	acyl-CoA dehydrogenase activity
AOT16_05495	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AOT16_05500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOT16_05515	COG2223	nitrite transmembrane transporter activity
AOT16_05525	COG0024	Methionine aminopeptidase
AOT16_05530	COG0052	Belongs to the universal ribosomal protein uS2 family
AOT16_05545	COG2207	Transcriptional regulator
AOT16_05570	COG2951	lytic endotransglycosylase activity
AOT16_05575	COG0772	Belongs to the SEDS family
AOT16_05590	COG0842	Transport permease protein
AOT16_05595	COG1131	(ABC) transporter
AOT16_05630	COG1538	Outer membrane efflux protein
AOT16_05640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOT16_05655	COG4215	(ABC) transporter
AOT16_05660	COG4160	amino acid transport
AOT16_05665	COG4598	ABC transporter
AOT16_05675	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AOT16_05685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOT16_05700	COG1720	tRNA m6t6A37 methyltransferase activity
AOT16_05720	COG0745	RESPONSE REGULATOR receiver
AOT16_05725	COG0642	Histidine kinase
AOT16_05735	COG0494	nUDIX hydrolase
AOT16_05745	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOT16_05750	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AOT16_05755	COG3139	Protein of unknown function (DUF1315)
AOT16_05760	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AOT16_05765	COG1301	dicarboxylic acid transport
AOT16_05770	COG1960	acyl-CoA dehydrogenase activity
AOT16_05775	COG2819	hydrolase of the alpha beta superfamily
AOT16_05785	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AOT16_05795	COG2195	Cleaves the N-terminal amino acid of tripeptides
AOT16_05800	COG1234	tRNA 3'-trailer cleavage
AOT16_05830	COG2363	Small membrane protein
AOT16_05850	COG0513	Belongs to the DEAD box helicase family
AOT16_05860	COG0778	Nitroreductase
AOT16_05890	COG1286	toxin biosynthetic process
AOT16_05915	COG4783	chaperone-mediated protein folding
AOT16_05920	COG1610	YqeY-like protein
AOT16_05925	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AOT16_06020	COG3111	PFAM Bacterial OB fold (BOF) protein
AOT16_06045	COG3243	poly(R)-hydroxyalkanoic acid synthase
AOT16_06050	COG0786	glutamate:sodium symporter activity
AOT16_06060	COG2186	Transcriptional regulator
AOT16_06110	COG0477	Major facilitator Superfamily
AOT16_06135	COG2985	domain, Protein
AOT16_06145	COG2995	paraquat-inducible protein a
AOT16_06150	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AOT16_06150	COG3008	intermembrane lipid transfer
AOT16_06160	COG1794	racemase activity, acting on amino acids and derivatives
AOT16_06180	COG3316	Transposase and inactivated derivatives
AOT16_06190	COG3316	Transposase and inactivated derivatives
AOT16_06260	COG3173	Aminoglycoside phosphotransferase
AOT16_06270	COG2433	Pfam Transposase IS66
AOT16_06295	COG3316	Transposase and inactivated derivatives
AOT16_06310	COG1301	dicarboxylic acid transport
AOT16_06320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOT16_06325	COG2011	ABC-type metal ion transport system permease component
AOT16_06330	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AOT16_06335	COG1464	Belongs to the NlpA lipoprotein family
AOT16_06340	COG0151	Belongs to the GarS family
AOT16_06345	COG0138	bifunctional purine biosynthesis protein purh
AOT16_06350	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AOT16_06380	COG2308	Evidence 4 Homologs of previously reported genes of
AOT16_06390	COG1305	Transglutaminase-like
AOT16_06400	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AOT16_06405	COG0305	Participates in initiation and elongation during chromosome replication
AOT16_06430	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AOT16_06440	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AOT16_06445	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AOT16_06470	COG1649	PFAM Uncharacterised BCR, COG1649
AOT16_06470	COG0726	polysaccharide deacetylase
AOT16_06475	COG1215	transferase activity, transferring glycosyl groups
AOT16_06480	COG3658	cytochrome
AOT16_06490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOT16_06505	COG0583	DNA-binding transcription factor activity
AOT16_06525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOT16_06530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOT16_06545	COG1960	acyl-CoA dehydrogenase activity
AOT16_06550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOT16_06555	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOT16_06580	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AOT16_06585	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AOT16_06595	COG2205	protein histidine kinase activity
AOT16_06600	COG0745	RESPONSE REGULATOR receiver
AOT16_06605	COG0174	glutamine synthetase
AOT16_06625	COG0729	surface antigen
AOT16_06650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOT16_06655	COG2814	Major facilitator Superfamily
AOT16_06670	COG0583	DNA-binding transcription factor activity
AOT16_06685	COG1187	pseudouridine synthase activity
AOT16_06705	COG0802	atpase or kinase
AOT16_06710	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AOT16_06720	COG1923	regulation of RNA biosynthetic process
AOT16_06725	COG0697	spore germination
AOT16_06740	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AOT16_06755	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AOT16_06755	COG0519	Catalyzes the synthesis of GMP from XMP
AOT16_06760	COG4302	ethanolamine ammonia-lyase activity
AOT16_06765	COG4303	Ethanolamine ammonia lyase large subunit
AOT16_06770	COG0531	amino acid
AOT16_06790	COG1454	alcohol dehydrogenase
AOT16_06795	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AOT16_06805	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AOT16_06825	COG0308	aminopeptidase N
AOT16_06835	COG4221	oxidoreductase activity
AOT16_06845	COG1605	Chorismate mutase
AOT16_06860	COG1309	transcriptional regulator
AOT16_06870	COG0668	transmembrane transport
AOT16_06910	COG4773	Receptor
AOT16_06930	COG0488	(ABC) transporter
AOT16_06935	COG0589	response to stress
AOT16_06955	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AOT16_06965	COG3135	benzoate transporter
AOT16_06970	COG1522	sequence-specific DNA binding
AOT16_06985	COG0583	DNA-binding transcription factor activity
AOT16_06995	COG0183	Belongs to the thiolase family
AOT16_07025	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AOT16_07035	COG0824	Thioesterase
AOT16_07040	COG1454	alcohol dehydrogenase
AOT16_07050	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AOT16_07070	COG0069	glutamate synthase activity
AOT16_07475	COG2814	Major facilitator Superfamily
AOT16_07490	COG0511	ligase activity, forming carbon-carbon bonds
AOT16_07505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOT16_07505	COG1116	anion transmembrane transporter activity
AOT16_07510	COG0745	RESPONSE REGULATOR receiver
AOT16_07520	COG2146	nitrite reductase [NAD(P)H] activity
AOT16_07520	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOT16_07525	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOT16_07530	COG0243	molybdopterin cofactor binding
AOT16_07540	COG0243	molybdopterin cofactor binding
AOT16_07545	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AOT16_07560	COG0315	cyclic pyranopterin monophosphate synthase activity
AOT16_07560	COG0521	Mo-molybdopterin cofactor biosynthetic process
AOT16_07565	COG0303	'Molybdopterin
AOT16_07575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOT16_07580	COG0697	spore germination
AOT16_07600	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AOT16_07605	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOT16_07685	COG2204	response regulator
AOT16_07690	COG3852	Histidine kinase
AOT16_07710	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AOT16_07715	COG0575	Belongs to the CDS family
AOT16_07750	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AOT16_07765	COG2137	regulation of response to DNA damage stimulus
AOT16_07775	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AOT16_07780	COG1011	Hydrolase
AOT16_07805	COG1522	sequence-specific DNA binding
AOT16_07815	COG1113	amino acid transport
AOT16_07830	COG0659	secondary active sulfate transmembrane transporter activity
AOT16_07835	COG2135	peptidase activity
AOT16_07850	COG5001	Diguanylate cyclase
AOT16_07850	COG3300	MHYT domain
AOT16_07870	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AOT16_07870	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AOT16_07870	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AOT16_07875	COG1105	Belongs to the carbohydrate kinase PfkB family
AOT16_07880	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AOT16_07880	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOT16_07910	COG0024	Methionine aminopeptidase
AOT16_07915	COG0583	DNA-binding transcription factor activity
AOT16_07925	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AOT16_07930	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AOT16_07935	COG0516	GMP reductase activity
AOT16_07935	COG0517	IMP dehydrogenase activity
AOT16_07960	COG0552	protein localization to endoplasmic reticulum
AOT16_07970	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AOT16_07985	COG4890	Cyd operon protein YbgT
AOT16_07990	COG1294	oxidase, subunit
AOT16_08005	COG1585	Membrane protein implicated in regulation of membrane protease activity
AOT16_08015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOT16_08020	COG4774	siderophore transport
AOT16_08035	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AOT16_08040	COG0569	domain protein
AOT16_08045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AOT16_08075	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AOT16_08080	COG0542	response to heat
AOT16_08090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AOT16_08105	COG1902	pentaerythritol trinitrate reductase activity
AOT16_08105	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOT16_08150	COG2323	membrane
AOT16_08155	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AOT16_08165	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AOT16_08170	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AOT16_08175	COG0183	Belongs to the thiolase family
AOT16_08180	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AOT16_08185	COG0596	Alpha beta hydrolase
AOT16_08190	COG2271	Major facilitator Superfamily
AOT16_08195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AOT16_08200	COG3485	protocatechuate 3,4-dioxygenase
AOT16_08205	COG3485	protocatechuate 3,4-dioxygenase
AOT16_08210	COG0710	3-dehydroquinate dehydratase activity
AOT16_08215	COG3420	alginic acid biosynthetic process
AOT16_08220	COG3659	wide pore channel activity
AOT16_08225	COG4993	Dehydrogenase
AOT16_08235	COG2391	methyltransferase activity
AOT16_08250	COG1414	Transcriptional regulator
AOT16_08255	COG0583	DNA-binding transcription factor activity
AOT16_08260	COG1960	acyl-CoA dehydrogenase activity
AOT16_08285	COG2814	Major facilitator Superfamily
AOT16_08295	COG0154	amidase activity
AOT16_08315	COG4638	Rieske (2fe-2S)
AOT16_08325	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_08335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOT16_08345	COG3733	amine oxidase
AOT16_08355	COG1012	belongs to the aldehyde dehydrogenase family
AOT16_08365	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOT16_08370	COG0183	Belongs to the thiolase family
AOT16_08375	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AOT16_08380	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AOT16_08390	COG4829	muconolactone delta-isomerase
AOT16_08395	COG4948	Mandelate Racemase Muconate Lactonizing
AOT16_08400	COG0583	DNA-binding transcription factor activity
AOT16_08410	COG2186	Transcriptional regulator
AOT16_08430	COG1012	belongs to the aldehyde dehydrogenase family
AOT16_08450	COG1960	acyl-CoA dehydrogenase activity
AOT16_08460	COG3829	transcription factor binding
AOT16_08470	COG3162	membrane
AOT16_08485	COG1012	belongs to the aldehyde dehydrogenase family
AOT16_08500	COG0753	catalase activity
AOT16_08525	COG1846	Transcriptional regulator
AOT16_08530	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOT16_08530	COG1902	pentaerythritol trinitrate reductase activity
AOT16_08540	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AOT16_08570	COG1309	transcriptional regulator
AOT16_08580	COG1335	isochorismatase
AOT16_08585	COG0583	DNA-binding transcription factor activity
AOT16_08595	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AOT16_08595	COG0475	glutathione-regulated potassium exporter activity
AOT16_08605	COG1473	amidohydrolase
AOT16_08615	COG2831	hemolysin activation secretion protein
AOT16_08620	COG3210	domain, Protein
AOT16_08680	COG0583	DNA-binding transcription factor activity
AOT16_08705	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AOT16_08710	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AOT16_08730	COG1566	PFAM secretion protein HlyD family protein
AOT16_08745	COG1012	belongs to the aldehyde dehydrogenase family
AOT16_08750	COG0129	dihydroxy-acid dehydratase activity
AOT16_08760	COG0583	DNA-binding transcription factor activity
AOT16_08765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOT16_08775	COG2084	Dehydrogenase
AOT16_08780	COG2207	Transcriptional regulator
AOT16_08795	COG1064	alcohol dehydrogenase
AOT16_08810	COG1120	ATPase activity
AOT16_08830	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AOT16_08945	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AOT16_08995	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_09010	COG2207	Transcriptional regulator
AOT16_09020	COG2205	protein histidine kinase activity
AOT16_09025	COG0745	RESPONSE REGULATOR receiver
AOT16_09030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOT16_09035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOT16_09040	COG1538	Outer membrane efflux protein
AOT16_09050	COG2072	flavoprotein involved in K transport
AOT16_09070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOT16_09090	COG3539	Fimbrial protein
AOT16_09125	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AOT16_09135	COG0753	catalase activity
AOT16_09150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AOT16_09210	COG3433	isochorismatase activity
AOT16_09210	COG1535	isochorismatase
AOT16_09215	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_09220	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AOT16_09225	COG4149	molybdate abc transporter
AOT16_09230	COG0725	ABC transporter, periplasmic molybdate-binding protein
AOT16_09240	COG4638	Rieske (2fe-2S)
AOT16_09245	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AOT16_09250	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOT16_09250	COG0543	2 iron, 2 sulfur cluster binding
AOT16_09265	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOT16_09275	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_09280	COG0412	Dienelactone hydrolase
AOT16_09290	COG2207	Transcriptional regulator
AOT16_09305	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_09310	COG2610	gluconate transmembrane transporter activity
AOT16_09320	COG0583	DNA-binding transcription factor activity
AOT16_09330	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AOT16_09335	COG2031	fatty acid transporter
AOT16_09340	COG0183	Belongs to the thiolase family
AOT16_09345	COG0583	DNA-binding transcription factor activity
AOT16_09350	COG0583	DNA-binding transcription factor activity
AOT16_09365	COG1027	Aspartate ammonia-lyase
AOT16_09375	COG0477	Major facilitator Superfamily
AOT16_09395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOT16_09400	COG4521	taurine ABC transporter
AOT16_09425	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AOT16_09430	COG1733	regulation of RNA biosynthetic process
AOT16_09435	COG3708	Transcriptional regulator
AOT16_09435	COG2207	Transcriptional regulator
AOT16_09450	COG0730	response to heat
AOT16_09460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOT16_09460	COG3453	Protein conserved in bacteria
AOT16_09470	COG3781	membrane
AOT16_09475	COG1063	alcohol dehydrogenase
AOT16_09485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOT16_09490	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOT16_09495	COG0022	dehydrogenase e1 component
AOT16_09500	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AOT16_09505	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AOT16_09520	COG3706	GGDEF domain
AOT16_09535	COG0133	tryptophan synthase activity
AOT16_09545	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOT16_09580	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AOT16_09605	COG2226	methyltransferase
AOT16_09660	COG0842	Transport permease protein
AOT16_09665	COG0842	Transport permease protein
AOT16_09670	COG1131	(ABC) transporter
AOT16_09685	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AOT16_09690	COG4773	Receptor
AOT16_09710	COG0730	response to heat
AOT16_09715	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AOT16_09735	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AOT16_09750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AOT16_09790	COG4264	IucA IucC family
AOT16_09795	COG4264	IucA IucC family
AOT16_09815	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AOT16_09830	COG1960	acyl-CoA dehydrogenase activity
AOT16_09835	COG1960	acyl-CoA dehydrogenase activity
AOT16_09840	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOT16_09845	COG2207	Transcriptional regulator
AOT16_09850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AOT16_09855	COG0776	regulation of translation
AOT16_09880	COG0822	iron-sulfur transferase activity
AOT16_09885	COG0316	Belongs to the HesB IscA family
AOT16_09915	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AOT16_09935	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AOT16_09940	COG0702	epimerase
AOT16_09975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOT16_09985	COG0339	signal peptide processing
AOT16_10030	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AOT16_10035	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AOT16_10065	COG0776	regulation of translation
AOT16_10085	COG0590	tRNA wobble adenosine to inosine editing
AOT16_10115	COG2165	general secretion pathway protein
AOT16_10130	COG0084	hydrolase, TatD family'
AOT16_10150	COG1663	tetraacyldisaccharide 4'-kinase activity
AOT16_10155	COG1132	(ABC) transporter
AOT16_10165	COG0811	peptide transport
AOT16_10170	COG1475	DNA binding
AOT16_10175	COG1192	Involved in chromosome partitioning
AOT16_10185	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AOT16_10200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AOT16_10205	COG0191	fructose-bisphosphate aldolase activity
AOT16_10225	COG0424	maF-like protein
AOT16_10230	COG2850	peptidyl-arginine hydroxylation
AOT16_10240	COG0640	Transcriptional regulator
AOT16_10250	COG3619	membrane
AOT16_10255	COG3122	Protein conserved in bacteria
AOT16_10260	COG1132	(ABC) transporter
AOT16_10280	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AOT16_10285	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOT16_10295	COG0506	proline dehydrogenase activity
AOT16_10295	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AOT16_10295	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AOT16_10300	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AOT16_10315	COG3698	Phosphodiester glycosidase
AOT16_10335	COG1765	OsmC-like protein
AOT16_10355	COG2353	YceI-like domain
AOT16_10365	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AOT16_10410	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AOT16_10410	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AOT16_10435	COG3539	Fimbrial protein
AOT16_10440	COG3121	Chaperone
AOT16_10465	COG0697	spore germination
AOT16_10475	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AOT16_10485	COG0583	DNA-binding transcription factor activity
AOT16_10505	COG1309	transcriptional regulator
AOT16_10520	COG1522	sequence-specific DNA binding
AOT16_10530	COG1126	abc transporter atp-binding protein
AOT16_10535	COG0765	amino acid transport
AOT16_10540	COG0765	amino acid transport
AOT16_10570	COG1464	Belongs to the NlpA lipoprotein family
AOT16_10580	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AOT16_10585	COG2011	ABC-type metal ion transport system permease component
AOT16_10590	COG0012	GTP binding
AOT16_10615	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AOT16_10655	COG0386	Belongs to the glutathione peroxidase family
AOT16_10665	COG0436	Aminotransferase
AOT16_10705	COG3634	alkyl hydroperoxide reductase activity
AOT16_10720	COG0583	DNA-binding transcription factor activity
AOT16_10725	COG0798	PFAM Bile acid sodium symporter
AOT16_10730	COG0640	Transcriptional regulator
AOT16_10745	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AOT16_10755	COG0583	DNA-binding transcription factor activity
AOT16_10765	COG1953	Uracil, thiamine, allantoin
AOT16_10775	COG2175	clavaminate synthase activity
AOT16_10780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOT16_10785	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AOT16_10790	COG4521	taurine ABC transporter
AOT16_10800	COG0477	Major facilitator Superfamily
AOT16_10820	COG1271	oxidase subunit
AOT16_10825	COG1294	oxidase, subunit
AOT16_10835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOT16_10855	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AOT16_10875	COG3052	prosthetic group binding
AOT16_10880	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AOT16_10890	COG2814	Major facilitator Superfamily
AOT16_10910	COG1346	cytolysis
AOT16_10920	COG0583	DNA-binding transcription factor activity
AOT16_10925	COG0625	glutathione transferase activity
AOT16_10930	COG0625	glutathione transferase activity
AOT16_10935	COG0583	DNA-binding transcription factor activity
AOT16_10950	COG1045	serine acetyltransferase
AOT16_10955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOT16_10960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AOT16_10965	COG1280	lysine exporter protein (LysE YggA)
AOT16_10975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOT16_10980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOT16_10985	COG1126	abc transporter atp-binding protein
AOT16_10990	COG0765	amino acid transport
AOT16_10995	COG0765	amino acid transport
AOT16_11030	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AOT16_11050	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_11100	COG0583	DNA-binding transcription factor activity
AOT16_11120	COG0318	PFAM AMP-dependent synthetase and ligase
AOT16_11125	COG1309	transcriptional regulator
AOT16_11130	COG1960	acyl-CoA dehydrogenase activity
AOT16_11135	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AOT16_11140	COG1024	Enoyl-CoA hydratase
AOT16_11155	COG0583	DNA-binding transcription factor activity
AOT16_11170	COG1960	acyl-CoA dehydrogenase activity
AOT16_11180	COG2814	Major facilitator Superfamily
AOT16_11190	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AOT16_11195	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AOT16_11200	COG2814	Major facilitator Superfamily
AOT16_11205	COG1960	acyl-CoA dehydrogenase activity
AOT16_11210	COG1024	Enoyl-CoA hydratase
AOT16_11215	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_11220	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOT16_11225	COG0183	Belongs to the thiolase family
AOT16_11235	COG2814	Major facilitator Superfamily
AOT16_11245	COG1024	Enoyl-CoA hydratase
AOT16_11260	COG1960	acyl-CoA dehydrogenase activity
AOT16_11265	COG2814	Major facilitator Superfamily
AOT16_11270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AOT16_11275	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AOT16_11290	COG3842	ATPase activity
AOT16_11295	COG1840	ABC-type Fe3 transport system, periplasmic component
AOT16_11305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOT16_11310	COG1414	Transcriptional regulator
AOT16_11320	COG0583	DNA-binding transcription factor activity
AOT16_11325	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AOT16_11330	COG1012	belongs to the aldehyde dehydrogenase family
AOT16_11340	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AOT16_11345	COG1012	belongs to the aldehyde dehydrogenase family
AOT16_11350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOT16_11355	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOT16_11360	COG2267	carboxylic ester hydrolase activity
AOT16_11380	COG3038	cytochrome b561
AOT16_11385	COG0753	catalase activity
AOT16_11420	COG2050	protein possibly involved in aromatic compounds catabolism
AOT16_11430	COG3327	negative regulation of DNA-templated transcription, initiation
AOT16_11435	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AOT16_11440	COG0183	Belongs to the thiolase family
AOT16_11445	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOT16_11450	COG1024	Enoyl-CoA hydratase
AOT16_11455	COG1024	Enoyl-CoA hydratase
AOT16_11460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOT16_11465	COG2151	metal-sulfur cluster biosynthetic enzyme
AOT16_11470	COG3396	Phenylacetate-CoA oxygenase
AOT16_11475	COG3460	Phenylacetate-CoA oxygenase
AOT16_11480	COG3396	Phenylacetate-CoA oxygenase
AOT16_11485	COG1012	belongs to the aldehyde dehydrogenase family
AOT16_11485	COG2030	dehydratase
AOT16_11490	COG1760	l-serine dehydratase
AOT16_11495	COG0531	amino acid
AOT16_11500	COG1012	belongs to the aldehyde dehydrogenase family
AOT16_11515	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOT16_11525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOT16_11545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOT16_11555	COG0789	Transcriptional regulator
AOT16_11575	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AOT16_11590	COG2807	transmembrane transport
AOT16_11595	COG0590	tRNA wobble adenosine to inosine editing
AOT16_11605	COG0583	DNA-binding transcription factor activity
AOT16_11645	COG2885	chlorophyll binding
AOT16_11645	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AOT16_11710	COG1116	anion transmembrane transporter activity
AOT16_11715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOT16_11725	COG0864	Transcriptional regulator
AOT16_11740	COG1733	regulation of RNA biosynthetic process
AOT16_11745	COG2249	NAD(P)H dehydrogenase (quinone) activity
AOT16_11750	COG0439	Biotin carboxylase
AOT16_11765	COG1063	alcohol dehydrogenase
AOT16_11775	COG1309	transcriptional regulator
AOT16_11800	COG0038	chloride channel
AOT16_11805	COG4770	biotin carboxylase activity
AOT16_11825	COG1914	H( )-stimulated, divalent metal cation uptake system
AOT16_11830	COG0583	DNA-binding transcription factor activity
AOT16_11845	COG3209	COG3209 Rhs family protein
AOT16_11850	COG3501	Rhs element vgr protein
AOT16_11875	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOT16_11895	COG2814	Major facilitator Superfamily
AOT16_11905	COG1560	Kdo2-lipid A biosynthetic process
AOT16_11915	COG5006	permease, DMT superfamily
AOT16_11920	COG1522	sequence-specific DNA binding
AOT16_11935	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AOT16_11975	COG1538	Outer membrane efflux protein
AOT16_11980	COG1137	ATPase activity
AOT16_11985	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AOT16_11995	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AOT16_12000	COG0517	IMP dehydrogenase activity
AOT16_12000	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AOT16_12035	COG1733	regulation of RNA biosynthetic process
AOT16_12040	COG2814	Major facilitator Superfamily
AOT16_12070	COG1278	Cold shock
AOT16_12075	COG1280	lysine exporter protein (LysE YggA)
AOT16_12110	COG1570	exodeoxyribonuclease VII activity
AOT16_12160	COG0583	DNA-binding transcription factor activity
AOT16_12165	COG4638	Rieske (2fe-2S)
AOT16_12170	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AOT16_12175	COG0633	Ferredoxin
AOT16_12175	COG0543	2 iron, 2 sulfur cluster binding
AOT16_12180	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_12185	COG3135	benzoate transporter
AOT16_12190	COG2814	Major facilitator Superfamily
AOT16_12205	COG1643	Atp-dependent helicase
AOT16_12210	COG0450	alkyl hydroperoxide reductase
AOT16_12220	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AOT16_12230	COG3634	alkyl hydroperoxide reductase activity
AOT16_12250	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AOT16_12255	COG0625	glutathione transferase activity
AOT16_12265	COG2885	chlorophyll binding
AOT16_12325	COG1765	OsmC-like protein
AOT16_12345	COG0667	Aldo Keto reductase
AOT16_12360	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AOT16_12370	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AOT16_12390	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AOT16_12400	COG3038	cytochrome b561
AOT16_12405	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AOT16_12410	COG2252	PERMEase
AOT16_12420	COG2072	flavoprotein involved in K transport
AOT16_12435	COG1741	Belongs to the pirin family
AOT16_12440	COG1309	transcriptional regulator
AOT16_12450	COG0300	oxidoreductase activity
AOT16_12455	COG2072	flavoprotein involved in K transport
AOT16_12460	COG3316	Transposase and inactivated derivatives
AOT16_12475	COG3316	Transposase and inactivated derivatives
AOT16_12480	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AOT16_12490	COG3316	Transposase and inactivated derivatives
AOT16_12505	COG3316	Transposase and inactivated derivatives
AOT16_12510	COG1113	amino acid transport
AOT16_12530	COG1012	belongs to the aldehyde dehydrogenase family
AOT16_12550	COG0531	amino acid
AOT16_12560	COG1113	amino acid transport
AOT16_12605	COG3209	COG3209 Rhs family protein
AOT16_12610	COG3501	Rhs element vgr protein
AOT16_12630	COG4269	membrane
AOT16_12645	COG1902	pentaerythritol trinitrate reductase activity
AOT16_12645	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOT16_12655	COG2203	Gaf domain
AOT16_12655	COG5001	Diguanylate cyclase
AOT16_12655	COG3706	GGDEF domain
AOT16_12655	COG4251	negative regulation of phosphorylation
AOT16_12665	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AOT16_12685	COG4172	Belongs to the ABC transporter superfamily
AOT16_12690	COG4239	(ABC) transporter, permease
AOT16_12695	COG4174	ABC transporter (Permease)
AOT16_12705	COG1388	LysM domain
AOT16_12705	COG0741	lytic transglycosylase activity
AOT16_12705	COG1388	LysM domain
AOT16_12705	COG0741	lytic transglycosylase activity
AOT16_12710	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AOT16_12750	COG0583	DNA-binding transcription factor activity
AOT16_12755	COG1279	arginine transmembrane transporter activity
AOT16_12775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOT16_12780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOT16_12820	COG2194	sulfuric ester hydrolase activity
AOT16_12870	COG0739	heme binding
AOT16_13185	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AOT16_13210	COG3384	dioxygenase
AOT16_13220	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AOT16_13225	COG2878	Part of a membrane complex involved in electron transport
AOT16_13230	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AOT16_13250	COG0768	penicillin binding
AOT16_13255	COG0742	ribosomal rna small subunit methyltransferase
AOT16_13270	COG0830	nickel cation binding
AOT16_13280	COG0804	urea catabolic process
AOT16_13320	COG1253	flavin adenine dinucleotide binding
AOT16_13330	COG2851	Citrate transporter
AOT16_13375	COG1773	rubredoxin
AOT16_13380	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOT16_13390	COG0583	DNA-binding transcription factor activity
AOT16_13415	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AOT16_13420	COG4181	ATPase activity
AOT16_13465	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AOT16_13485	COG0306	phosphate transporter
AOT16_13495	COG3958	Transketolase
AOT16_13500	COG3959	Transketolase, thiamine diphosphate binding domain
AOT16_13505	COG2271	Major facilitator Superfamily
AOT16_13510	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_13515	COG0583	DNA-binding transcription factor activity
AOT16_13530	COG2223	nitrite transmembrane transporter activity
AOT16_13535	COG2207	Transcriptional regulator
AOT16_13540	COG2066	Belongs to the glutaminase family
AOT16_13545	COG0242	peptide deformylase activity
AOT16_13550	COG0477	Major facilitator Superfamily
AOT16_13560	COG0028	Belongs to the TPP enzyme family
AOT16_13575	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_13580	COG2267	carboxylic ester hydrolase activity
AOT16_13590	COG2271	Major facilitator Superfamily
AOT16_13595	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOT16_13605	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_13625	COG1414	Transcriptional regulator
AOT16_13640	COG1024	Enoyl-CoA hydratase
AOT16_13650	COG1215	transferase activity, transferring glycosyl groups
AOT16_13655	COG1649	PFAM Uncharacterised BCR, COG1649
AOT16_13655	COG0726	polysaccharide deacetylase
AOT16_13665	COG4681	YaeQ
AOT16_13675	COG0523	cobalamin synthesis protein
AOT16_13685	COG1607	acyl-coa hydrolase
AOT16_13695	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOT16_13700	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOT16_13705	COG1309	transcriptional regulator
AOT16_13730	COG2040	homocysteine
AOT16_13735	COG0531	amino acid
AOT16_13760	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOT16_13765	COG0477	Major facilitator Superfamily
AOT16_13880	COG0592	DNA-directed DNA polymerase activity
AOT16_13920	COG2026	Addiction module toxin, RelE StbE family
AOT16_14065	COG3755	Protein conserved in bacteria
AOT16_14110	COG1484	DNA-dependent DNA replication
AOT16_14200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AOT16_14265	COG0405	Gamma-glutamyltransferase
AOT16_14270	COG2814	Major facilitator Superfamily
AOT16_14280	COG2050	protein possibly involved in aromatic compounds catabolism
AOT16_14295	COG1090	epimerase
AOT16_14315	COG0420	3'-5' exonuclease activity
AOT16_14340	COG0735	belongs to the Fur family
AOT16_14345	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AOT16_14370	COG0121	glutamine amidotransferase
AOT16_14385	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOT16_14395	COG0210	DNA helicase
AOT16_14400	COG2885	chlorophyll binding
AOT16_14405	COG0204	Acyl-transferase
AOT16_14420	COG2894	cell division
AOT16_14440	COG1280	lysine exporter protein (LysE YggA)
AOT16_14445	COG1674	ftsk spoiiie
AOT16_14445	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AOT16_14450	COG0492	ferredoxin-NADP+ reductase activity
AOT16_14455	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AOT16_14465	COG0456	acetyltransferase
AOT16_14525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOT16_14525	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AOT16_14545	COG1012	belongs to the aldehyde dehydrogenase family
AOT16_14565	COG0473	3-isopropylmalate dehydrogenase activity
AOT16_14570	COG0583	DNA-binding transcription factor activity
AOT16_14590	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AOT16_14615	COG0564	pseudouridine synthase activity
AOT16_14625	COG0358	DNA primase activity
AOT16_14640	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AOT16_14670	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AOT16_14700	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AOT16_14710	COG0351	phosphomethylpyrimidine kinase
AOT16_14710	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AOT16_14710	COG0352	thiamine-phosphate diphosphorylase activity
AOT16_14715	COG1652	LysM domain
AOT16_14740	COG1399	metal-binding, possibly nucleic acid-binding protein
AOT16_14745	COG3101	peptidyl-lysine hydroxylation
AOT16_14750	COG0009	L-threonylcarbamoyladenylate synthase
AOT16_14755	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AOT16_14760	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AOT16_14775	COG4106	trans-aconitate 2-methyltransferase activity
AOT16_14790	COG0596	Alpha beta hydrolase
AOT16_14790	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOT16_14790	COG2226	methyltransferase
AOT16_14795	COG1877	trehalose-phosphatase activity
AOT16_14800	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AOT16_14805	COG2223	nitrite transmembrane transporter activity
AOT16_14825	COG1196	nuclear chromosome segregation
AOT16_14835	COG0730	response to heat
AOT16_14850	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AOT16_14860	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AOT16_14910	COG0489	protein tyrosine kinase activity
AOT16_14920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOT16_14920	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOT16_14950	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AOT16_14955	COG2081	HI0933 family
AOT16_14965	COG0668	transmembrane transport
AOT16_14985	COG0583	DNA-binding transcription factor activity
AOT16_15005	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOT16_15010	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AOT16_15040	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AOT16_15075	COG2205	protein histidine kinase activity
AOT16_15080	COG0745	RESPONSE REGULATOR receiver
AOT16_15100	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOT16_15110	COG2205	protein histidine kinase activity
AOT16_15180	COG4993	Dehydrogenase
AOT16_15200	COG0384	phenazine biosynthesis protein PhzF
AOT16_15225	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOT16_15230	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AOT16_15240	COG0583	DNA-binding transcription factor activity
AOT16_15260	COG1473	amidohydrolase
AOT16_15270	COG0583	DNA-binding transcription factor activity
AOT16_15285	COG0583	DNA-binding transcription factor activity
AOT16_15290	COG1053	succinate dehydrogenase
AOT16_15300	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AOT16_15305	COG2814	Major facilitator Superfamily
AOT16_15310	COG1960	acyl-CoA dehydrogenase activity
AOT16_15315	COG0583	DNA-binding transcription factor activity
AOT16_15320	COG1063	alcohol dehydrogenase
AOT16_15350	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AOT16_15355	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AOT16_15360	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AOT16_15375	COG3667	copper resistance
AOT16_15380	COG2132	Multicopper oxidase
AOT16_15390	COG0561	phosphatase activity
AOT16_15395	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AOT16_15420	COG1214	PFAM Peptidase M22, glycoprotease
AOT16_15490	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AOT16_15500	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AOT16_15505	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AOT16_15510	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AOT16_15570	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOT16_15580	COG1846	Transcriptional regulator
AOT16_15585	COG1764	response to oxidative stress
AOT16_15625	COG0037	tRNA processing
AOT16_15635	COG0248	Ppx GppA phosphatase
AOT16_15660	COG0072	phenylalanine-tRNA ligase activity
AOT16_15685	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AOT16_15700	COG1238	metal cluster binding
AOT16_15705	COG0625	glutathione transferase activity
AOT16_15720	COG0318	PFAM AMP-dependent synthetase and ligase
AOT16_15725	COG3028	Belongs to the UPF0307 family
AOT16_15730	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOT16_15750	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AOT16_15755	COG0617	tRNA 3'-terminal CCA addition
AOT16_15760	COG1555	photosystem II stabilization
AOT16_15765	COG3956	TIGRFAM MazG family protein
AOT16_15775	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AOT16_15795	COG2205	protein histidine kinase activity
AOT16_15795	COG0784	Response regulator, receiver
AOT16_15795	COG5002	protein histidine kinase activity
AOT16_15800	COG1024	Enoyl-CoA hydratase
AOT16_15805	COG2084	Dehydrogenase
AOT16_15810	COG3622	Belongs to the hyi family
AOT16_15825	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AOT16_15830	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AOT16_15835	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AOT16_15840	COG0697	spore germination
AOT16_15850	COG2814	Major facilitator Superfamily
AOT16_15855	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AOT16_15865	COG0583	DNA-binding transcription factor activity
AOT16_15870	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AOT16_15885	COG0084	hydrolase, TatD family'
AOT16_15900	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AOT16_15930	COG0440	acetolactate synthase activity
AOT16_15935	COG0028	Belongs to the TPP enzyme family
AOT16_15960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOT16_15965	COG1136	(ABC) transporter
AOT16_15965	COG0577	efflux transmembrane transporter activity
AOT16_15970	COG1538	Outer membrane efflux protein
AOT16_15985	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AOT16_15990	COG1162	GTPase activity
AOT16_16000	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AOT16_16020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AOT16_16025	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_16065	COG2986	histidine ammonia-lyase
AOT16_16080	COG0318	PFAM AMP-dependent synthetase and ligase
AOT16_16090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AOT16_16095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AOT16_16135	COG1426	Protein conserved in bacteria
AOT16_16170	COG0793	Belongs to the peptidase S41A family
AOT16_16185	COG2267	carboxylic ester hydrolase activity
AOT16_16195	COG1012	belongs to the aldehyde dehydrogenase family
AOT16_16200	COG3265	gluconokinase activity
AOT16_16210	COG0800	Aldolase
AOT16_16220	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AOT16_16225	COG0280	phosphate acetyltransferase
AOT16_16225	COG0857	belongs to the CobB CobQ family
AOT16_16230	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AOT16_16230	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AOT16_16250	COG0740	serine-type endopeptidase activity
AOT16_16260	COG4774	siderophore transport
AOT16_16270	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AOT16_16280	COG2813	Specifically methylates the guanine in position
AOT16_16280	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOT16_16380	COG0788	formyltetrahydrofolate deformylase activity
AOT16_16395	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AOT16_16400	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AOT16_16405	COG4651	solute:proton antiporter activity
AOT16_16405	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AOT16_16425	COG0724	RNA recognition motif
AOT16_16430	COG0210	DNA helicase
AOT16_16455	COG1733	regulation of RNA biosynthetic process
AOT16_16475	COG1280	lysine exporter protein (LysE YggA)
AOT16_16480	COG1560	Kdo2-lipid A biosynthetic process
AOT16_16490	COG1301	dicarboxylic acid transport
AOT16_16545	COG0473	3-isopropylmalate dehydrogenase activity
AOT16_16610	COG0583	DNA-binding transcription factor activity
AOT16_16620	COG0625	glutathione transferase activity
AOT16_16625	COG2378	regulation of single-species biofilm formation
AOT16_16630	COG0546	phosphoglycolate phosphatase activity
AOT16_16640	COG1530	ribonuclease E activity
AOT16_16660	COG0583	DNA-binding transcription factor activity
AOT16_16665	COG4221	oxidoreductase activity
AOT16_16670	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AOT16_16680	COG0534	Mate efflux family protein
AOT16_16695	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOT16_16730	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AOT16_16735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOT16_16750	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AOT16_16760	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AOT16_16760	COG0644	oxidoreductase
AOT16_16765	COG0425	Belongs to the sulfur carrier protein TusA family
AOT16_16770	COG4535	Mg2 and Co2 transporter CorC
AOT16_16780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOT16_16800	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AOT16_16805	COG0475	glutathione-regulated potassium exporter activity
AOT16_16805	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AOT16_16810	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AOT16_16820	COG0484	heat shock protein binding
AOT16_16825	COG0789	Transcriptional regulator
AOT16_16830	COG0598	Magnesium transport protein CorA
AOT16_16850	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AOT16_16855	COG1074	ATP-dependent DNA helicase activity
AOT16_16860	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AOT16_16880	COG2226	methyltransferase
AOT16_16895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOT16_16900	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AOT16_16915	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AOT16_16915	COG2111	Na H antiporter
AOT16_16920	COG1006	Multisubunit Na H antiporter MnhC subunit
AOT16_16925	COG0651	ATP synthesis coupled electron transport
AOT16_16935	COG2212	antiporter activity
AOT16_16955	COG0195	Participates in both transcription termination and antitermination
AOT16_17005	COG0237	dephospho-CoA kinase activity
AOT16_17015	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOT16_17030	COG0497	DNA recombination
AOT16_17040	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AOT16_17070	COG2169	Transcriptional regulator
AOT16_17070	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AOT16_17075	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AOT16_17140	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AOT16_17155	COG0326	Molecular chaperone. Has ATPase activity
AOT16_17170	COG2056	Na+-H+ antiporter family
AOT16_17175	COG0596	Alpha beta hydrolase
AOT16_17270	COG0546	phosphoglycolate phosphatase activity
AOT16_17275	COG1716	ATPase activity
AOT16_17320	COG0181	hydroxymethylbilane synthase activity
AOT16_17330	COG3275	phosphorelay sensor kinase activity
AOT16_17350	COG1538	Outer membrane efflux protein
AOT16_17355	COG0697	spore germination
AOT16_17380	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AOT16_17385	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AOT16_17390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AOT16_17395	COG0772	Belongs to the SEDS family
AOT16_17420	COG4974	Belongs to the 'phage' integrase family
AOT16_17425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AOT16_17435	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AOT16_17445	COG2197	response regulator
AOT16_17460	COG0793	Belongs to the peptidase S41A family
AOT16_17465	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AOT16_17470	COG0795	lipopolysaccharide-transporting ATPase activity
AOT16_17510	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AOT16_17510	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AOT16_17520	COG0004	ammonium transporteR
AOT16_17525	COG0347	Belongs to the P(II) protein family
AOT16_17585	COG0659	secondary active sulfate transmembrane transporter activity
AOT16_17590	COG0589	response to stress
AOT16_17630	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOT16_17680	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AOT16_17710	COG0659	secondary active sulfate transmembrane transporter activity
AOT16_17715	COG0589	response to stress
AOT16_17750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOT16_17760	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOT16_17775	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AOT16_17790	COG0318	PFAM AMP-dependent synthetase and ligase
AOT16_17800	COG0477	Major facilitator Superfamily
AOT16_17805	COG2860	membrane
AOT16_17815	COG1253	flavin adenine dinucleotide binding
AOT16_17835	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AOT16_17870	COG0655	NAD(P)H dehydrogenase (quinone) activity
AOT16_17880	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AOT16_17915	COG1309	transcriptional regulator
AOT16_17950	COG0758	DNA mediated transformation
AOT16_17960	COG0697	spore germination
AOT16_17965	COG1309	transcriptional regulator
AOT16_17980	COG0386	Belongs to the glutathione peroxidase family
AOT16_18045	COG1121	(ABC) transporter
AOT16_18050	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AOT16_18055	COG1280	lysine exporter protein (LysE YggA)
AOT16_18060	COG2837	iron assimilation
AOT16_18070	COG0281	malic enzyme
AOT16_18115	COG0519	Catalyzes the synthesis of GMP from XMP
AOT16_18115	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AOT16_18120	COG4399	Belongs to the UPF0754 family
AOT16_18125	COG2259	Doxx family
AOT16_18130	COG0586	Pfam SNARE associated Golgi protein
AOT16_18145	COG1192	Involved in chromosome partitioning
AOT16_18155	COG0271	Belongs to the BolA IbaG family
AOT16_18175	COG2267	carboxylic ester hydrolase activity
AOT16_18190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOT16_18200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AOT16_18200	COG3321	synthase
AOT16_18200	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AOT16_18200	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOT16_18205	COG1960	acyl-CoA dehydrogenase activity
AOT16_18215	COG2197	response regulator
AOT16_18225	COG3916	Acyl-homoserine-lactone synthase
AOT16_18230	COG0477	Major facilitator Superfamily
AOT16_18235	COG1024	Enoyl-CoA hydratase
AOT16_18240	COG1024	Enoyl-CoA hydratase
AOT16_18245	COG1960	acyl-CoA dehydrogenase activity
AOT16_18270	COG1113	amino acid transport
AOT16_18275	COG1113	amino acid transport
AOT16_18280	COG0251	oxidation-reduction process
AOT16_18295	COG1522	sequence-specific DNA binding
AOT16_18320	COG0564	pseudouridine synthase activity
AOT16_18370	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AOT16_18385	COG1802	Transcriptional regulator
AOT16_18390	COG1448	Aminotransferase
AOT16_18395	COG0277	FAD linked oxidase domain protein
AOT16_18405	COG2186	Transcriptional regulator
AOT16_18415	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOT16_18420	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOT16_18435	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AOT16_18440	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AOT16_18445	COG1216	Glycosyl transferase, family 2
AOT16_18475	COG2089	acid synthase
AOT16_18490	COG1083	cytidylyl-transferase
AOT16_18495	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AOT16_18500	COG1086	Polysaccharide biosynthesis protein
AOT16_18505	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AOT16_18510	COG1596	polysaccharide export
AOT16_18535	COG0728	peptidoglycan biosynthetic process
AOT16_18540	COG3023	N-Acetylmuramoyl-L-alanine amidase
AOT16_18595	COG0546	phosphoglycolate phosphatase activity
AOT16_18600	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_18620	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOT16_18625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOT16_18630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOT16_18635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOT16_18640	COG1116	anion transmembrane transporter activity
AOT16_18645	COG1309	transcriptional regulator
AOT16_18650	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AOT16_18660	COG0196	riboflavin kinase activity
AOT16_18665	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AOT16_18675	COG1047	Peptidyl-prolyl cis-trans
AOT16_18715	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AOT16_18740	COG0583	DNA-binding transcription factor activity
AOT16_18770	COG2951	lytic endotransglycosylase activity
AOT16_18775	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AOT16_18790	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AOT16_18800	COG0671	phosphoesterase, PA-phosphatase related
AOT16_18805	COG0861	Integral membrane protein TerC family
AOT16_18815	COG0754	glutathionylspermidine amidase activity
AOT16_18825	COG0402	S-adenosylhomocysteine deaminase activity
AOT16_18845	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AOT16_18850	COG1230	cation diffusion facilitator family transporter
AOT16_18865	COG0706	membrane insertase activity
AOT16_18880	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AOT16_18890	COG2130	NADP-dependent
AOT16_18935	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AOT16_18970	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOT16_18975	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AOT16_18975	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOT16_19025	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AOT16_19025	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AOT16_19040	COG0587	DNA-directed DNA polymerase activity
AOT16_19085	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AOT16_19110	COG0194	GDP metabolic process
AOT16_19140	COG0358	DNA primase activity
AOT16_19320	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AOT16_19340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AOT16_19355	COG1388	LysM domain
AOT16_19420	COG1063	alcohol dehydrogenase
AOT16_19450	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AOT16_19460	COG1979	alcohol dehydrogenase
AOT16_19470	COG1902	pentaerythritol trinitrate reductase activity
AOT16_19480	COG1309	transcriptional regulator
AOT16_19530	COG2826	transposase and inactivated derivatives, IS30 family
AOT16_19540	COG2826	transposase and inactivated derivatives, IS30 family
AOT16_19570	COG0741	lytic transglycosylase activity
AOT16_19605	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AOT16_19685	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AOT16_19755	COG1525	nuclease
AOT16_19840	COG1475	DNA binding
AOT16_19860	COG3853	Toxic anion resistance protein (TelA)
AOT16_19960	COG0484	heat shock protein binding