locus-tag	class	description
AOT18_00010	COG0592	DNA-directed DNA polymerase activity
AOT18_00020	COG0187	DNA topoisomerase II activity
AOT18_00030	COG0586	Pfam SNARE associated Golgi protein
AOT18_00035	COG0488	(ABC) transporter
AOT18_00060	COG0596	Alpha beta hydrolase
AOT18_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AOT18_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AOT18_00110	COG0733	neurotransmitter:sodium symporter activity
AOT18_00150	COG2233	PERMEase
AOT18_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOT18_00200	COG2814	Major facilitator Superfamily
AOT18_00205	COG0656	L-ascorbic acid biosynthetic process
AOT18_00210	COG0583	DNA-binding transcription factor activity
AOT18_00220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOT18_00225	COG1064	alcohol dehydrogenase
AOT18_00230	COG2818	Glycosylase
AOT18_00245	COG1194	a g-specific adenine glycosylase
AOT18_00265	COG2983	Belongs to the UPF0260 family
AOT18_00270	COG2133	pyrroloquinoline quinone binding
AOT18_00275	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AOT18_00280	COG2116	formate transmembrane transporter activity
AOT18_00300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOT18_00305	COG1335	isochorismatase
AOT18_00310	COG0385	Bile acid
AOT18_00315	COG0534	Mate efflux family protein
AOT18_00320	COG1683	Conserved Protein
AOT18_00340	COG0625	glutathione transferase activity
AOT18_00350	COG1113	amino acid transport
AOT18_00360	COG0523	cobalamin synthesis protein
AOT18_00370	COG2188	Transcriptional regulator
AOT18_00400	COG0010	Belongs to the arginase family
AOT18_00415	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AOT18_00420	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AOT18_00430	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AOT18_00435	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AOT18_00535	COG0534	Mate efflux family protein
AOT18_00540	COG0436	Aminotransferase
AOT18_00545	COG2733	membrane
AOT18_00560	COG2918	glutathione biosynthetic process
AOT18_00570	COG3501	Rhs element vgr protein
AOT18_00575	COG1388	LysM domain
AOT18_00575	COG0791	NLP P60 protein
AOT18_00600	COG3150	esterase
AOT18_00610	COG1028	Short-chain dehydrogenase reductase Sdr
AOT18_00615	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AOT18_00625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOT18_00635	COG2233	PERMEase
AOT18_00640	COG2351	hydroxyisourate hydrolase activity
AOT18_00675	COG3706	GGDEF domain
AOT18_00690	COG1393	Belongs to the ArsC family
AOT18_00695	COG0708	Exodeoxyribonuclease III
AOT18_00715	COG0189	ligase activity
AOT18_00735	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AOT18_00745	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AOT18_00760	COG4942	peptidase
AOT18_00770	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOT18_00780	COG2119	membrane
AOT18_00800	COG4774	siderophore transport
AOT18_00805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOT18_00805	COG0426	domain, Protein
AOT18_00830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AOT18_00850	COG1902	pentaerythritol trinitrate reductase activity
AOT18_00855	COG1519	Transferase
AOT18_00860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AOT18_00865	COG0668	transmembrane transport
AOT18_00875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOT18_00880	COG1335	isochorismatase
AOT18_00885	COG1522	sequence-specific DNA binding
AOT18_00890	COG3328	transposase activity
AOT18_00915	COG2205	protein histidine kinase activity
AOT18_00915	COG2198	Histidine kinase
AOT18_00915	COG0784	Response regulator, receiver
AOT18_00920	COG3162	membrane
AOT18_00925	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOT18_00935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOT18_00945	COG3706	GGDEF domain
AOT18_00955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AOT18_00960	COG1309	transcriptional regulator
AOT18_00980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AOT18_00980	COG0352	thiamine-phosphate diphosphorylase activity
AOT18_00980	COG0351	phosphomethylpyrimidine kinase
AOT18_00990	COG2814	Major facilitator Superfamily
AOT18_01005	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AOT18_01015	COG1113	amino acid transport
AOT18_01025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AOT18_01030	COG1012	belongs to the aldehyde dehydrogenase family
AOT18_01040	COG1335	isochorismatase
AOT18_01070	COG2814	Major facilitator Superfamily
AOT18_01075	COG0583	DNA-binding transcription factor activity
AOT18_01095	COG0667	Aldo Keto reductase
AOT18_01125	COG1733	regulation of RNA biosynthetic process
AOT18_01130	COG2249	NAD(P)H dehydrogenase (quinone) activity
AOT18_01195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AOT18_01210	COG2329	Antibiotic biosynthesis monooxygenase
AOT18_01240	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AOT18_01270	COG0427	acetyl-CoA hydrolase
AOT18_01280	COG0745	RESPONSE REGULATOR receiver
AOT18_01290	COG0659	secondary active sulfate transmembrane transporter activity
AOT18_01295	COG4221	oxidoreductase activity
AOT18_01305	COG0488	(ABC) transporter
AOT18_01385	COG0833	amino acid
AOT18_01430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AOT18_01435	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AOT18_01450	COG2226	methyltransferase
AOT18_01500	COG0067	glutamate synthase
AOT18_01500	COG0069	glutamate synthase activity
AOT18_01500	COG0070	glutamate synthase
AOT18_01505	COG0493	'glutamate synthase
AOT18_01515	COG1704	LemA family
AOT18_01520	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AOT18_01540	COG3307	-O-antigen
AOT18_01560	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AOT18_01570	COG0194	GDP metabolic process
AOT18_01620	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AOT18_01640	COG5380	lipid catabolic process
AOT18_01645	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AOT18_01670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AOT18_01675	COG0277	FAD linked oxidase domain protein
AOT18_01685	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AOT18_01690	COG2249	NAD(P)H dehydrogenase (quinone) activity
AOT18_01705	COG1289	transmembrane transporter activity
AOT18_01715	COG0628	permease
AOT18_01720	COG1192	Involved in chromosome partitioning
AOT18_01750	COG0833	amino acid
AOT18_01755	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AOT18_01760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AOT18_01770	COG1012	belongs to the aldehyde dehydrogenase family
AOT18_01810	COG0583	DNA-binding transcription factor activity
AOT18_01855	COG0517	IMP dehydrogenase activity
AOT18_01860	COG1983	PspC domain protein
AOT18_01870	COG1960	acyl-CoA dehydrogenase activity
AOT18_01885	COG0408	coproporphyrinogen oxidase activity
AOT18_01905	COG0513	Belongs to the DEAD box helicase family
AOT18_01915	COG1127	ABC transporter
AOT18_01920	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AOT18_01930	COG2854	intermembrane phospholipid transfer
AOT18_01940	COG0598	Magnesium transport protein CorA
AOT18_01950	COG0494	nUDIX hydrolase
AOT18_01955	COG1040	competence protein
AOT18_01960	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AOT18_01980	COG1946	Acyl-CoA thioesterase
AOT18_01985	COG1301	dicarboxylic acid transport
AOT18_02000	COG1959	2 iron, 2 sulfur cluster binding
AOT18_02005	COG1017	nitric oxide dioxygenase activity
AOT18_02005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOT18_02010	COG0433	COG0433 Predicted ATPase
AOT18_02015	COG0626	cystathionine gamma-synthase activity
AOT18_02135	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AOT18_02145	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AOT18_02170	COG1960	acyl-CoA dehydrogenase activity
AOT18_02175	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AOT18_02205	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AOT18_02210	COG0339	signal peptide processing
AOT18_02215	COG0557	exoribonuclease II activity
AOT18_02260	COG0179	Fumarylacetoacetate (FAA) hydrolase
AOT18_02265	COG2169	Transcriptional regulator
AOT18_02270	COG0697	spore germination
AOT18_02275	COG1295	ribonuclease BN
AOT18_02310	COG1702	phosphate starvation-inducible protein PhoH
AOT18_02320	COG0739	heme binding
AOT18_02320	COG0741	lytic transglycosylase activity
AOT18_02320	COG1196	nuclear chromosome segregation
AOT18_02350	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AOT18_02355	COG1183	phosphatidylcholine synthase activity
AOT18_02400	COG1960	acyl-CoA dehydrogenase activity
AOT18_02405	COG1309	transcriptional regulator
AOT18_02420	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AOT18_02425	COG1960	acyl-CoA dehydrogenase activity
AOT18_02445	COG2969	positive regulation of protein catabolic process
AOT18_02455	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AOT18_02470	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AOT18_02475	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AOT18_02495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AOT18_02505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AOT18_02510	COG1408	metallophosphoesterase
AOT18_02520	COG2199	diguanylate cyclase activity
AOT18_02565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOT18_02565	COG3453	Protein conserved in bacteria
AOT18_02580	COG1607	acyl-coa hydrolase
AOT18_02610	COG2350	Protein conserved in bacteria
AOT18_02620	COG0613	PHP domain protein
AOT18_02625	COG3781	membrane
AOT18_02635	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AOT18_02640	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AOT18_02650	COG1862	Preprotein translocase
AOT18_02695	COG2205	protein histidine kinase activity
AOT18_02700	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AOT18_02720	COG0726	polysaccharide deacetylase
AOT18_02725	COG0463	Glycosyl transferase, family 2
AOT18_02730	COG0438	transferase activity, transferring glycosyl groups
AOT18_02795	COG0625	glutathione transferase activity
AOT18_02800	COG0583	DNA-binding transcription factor activity
AOT18_02805	COG1960	acyl-CoA dehydrogenase activity
AOT18_02810	COG1960	acyl-CoA dehydrogenase activity
AOT18_02820	COG2205	protein histidine kinase activity
AOT18_02825	COG0745	RESPONSE REGULATOR receiver
AOT18_02830	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AOT18_02850	COG2096	Adenosyltransferase
AOT18_02865	COG0133	tryptophan synthase activity
AOT18_02900	COG0285	dihydrofolate synthase activity
AOT18_02920	COG0450	alkyl hydroperoxide reductase
AOT18_02935	COG0477	Major facilitator Superfamily
AOT18_02940	COG1272	protein, Hemolysin III
AOT18_02970	COG0183	Belongs to the thiolase family
AOT18_02975	COG2207	Transcriptional regulator
AOT18_02995	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOT18_03015	COG0183	Belongs to the thiolase family
AOT18_03025	COG2885	chlorophyll binding
AOT18_03025	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AOT18_03035	COG1690	Belongs to the RtcB family
AOT18_03040	COG0833	amino acid
AOT18_03050	COG2233	PERMEase
AOT18_03080	COG2094	Belongs to the DNA glycosylase MPG family
AOT18_03105	COG1902	pentaerythritol trinitrate reductase activity
AOT18_03110	COG0679	Auxin Efflux Carrier
AOT18_03120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AOT18_03125	COG0354	folic acid binding
AOT18_03135	COG3189	MarR family transcriptional regulator
AOT18_03140	COG2824	Alkylphosphonate utilization operon protein PhnA
AOT18_03145	COG3422	double-strand break repair
AOT18_03185	COG0840	transmembrane signaling receptor activity
AOT18_03205	COG5510	response to toxic substance
AOT18_03215	COG2832	Protein of unknown function (DUF454)
AOT18_03220	COG1376	ErfK ybiS ycfS ynhG family protein
AOT18_03270	COG1289	transmembrane transporter activity
AOT18_03275	COG2814	Major facilitator Superfamily
AOT18_03290	COG1115	amino acid carrier protein
AOT18_03295	COG1752	Esterase of the alpha-beta hydrolase superfamily
AOT18_03300	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AOT18_03305	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AOT18_03335	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AOT18_03345	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AOT18_03350	COG1077	Cell shape determining protein MreB Mrl
AOT18_03355	COG1792	Involved in formation and maintenance of cell shape
AOT18_03360	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AOT18_03365	COG0424	maF-like protein
AOT18_03370	COG1530	ribonuclease E activity
AOT18_03380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOT18_03400	COG2249	NAD(P)H dehydrogenase (quinone) activity
AOT18_03425	COG2207	Transcriptional regulator
AOT18_03445	COG1113	amino acid transport
AOT18_03450	COG2828	Protein conserved in bacteria
AOT18_03455	COG0142	geranyltranstransferase activity
AOT18_03460	COG2315	Protein conserved in bacteria
AOT18_03475	COG1752	Esterase of the alpha-beta hydrolase superfamily
AOT18_03495	COG2194	sulfuric ester hydrolase activity
AOT18_03500	COG0745	RESPONSE REGULATOR receiver
AOT18_03505	COG0642	Histidine kinase
AOT18_03515	COG0004	ammonium transporteR
AOT18_03520	COG0583	DNA-binding transcription factor activity
AOT18_03540	COG0525	valine-tRNA ligase activity
AOT18_03550	COG1028	Short-chain dehydrogenase reductase Sdr
AOT18_03560	COG0393	Putative heavy-metal-binding
AOT18_03565	COG0393	Putative heavy-metal-binding
AOT18_03570	COG1538	Outer membrane efflux protein
AOT18_03580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOT18_03585	COG0671	phosphoesterase, PA-phosphatase related
AOT18_03615	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AOT18_03630	COG1648	precorrin-2 dehydrogenase activity
AOT18_03630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AOT18_03635	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AOT18_03640	COG1733	regulation of RNA biosynthetic process
AOT18_03650	COG0531	amino acid
AOT18_03665	COG0321	lipoyl(octanoyl) transferase activity
AOT18_03670	COG2921	Belongs to the UPF0250 family
AOT18_03710	COG2009	succinate dehydrogenase
AOT18_03715	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AOT18_03720	COG1053	succinate dehydrogenase
AOT18_03725	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AOT18_03740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOT18_03760	COG2354	Protein conserved in bacteria
AOT18_03765	COG2321	neutral zinc metallopeptidase
AOT18_03790	COG2843	Capsule synthesis protein
AOT18_03805	COG0589	response to stress
AOT18_03825	COG0505	Belongs to the CarA family
AOT18_03850	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOT18_03855	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AOT18_03905	COG0477	Major facilitator Superfamily
AOT18_03910	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AOT18_03930	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AOT18_03955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOT18_03960	COG0584	glycerophosphoryl diester phosphodiesterase
AOT18_03980	COG0741	lytic transglycosylase activity
AOT18_04000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AOT18_04015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOT18_04040	COG0778	Nitroreductase
AOT18_04055	COG1929	Belongs to the glycerate kinase type-1 family
AOT18_04060	COG0243	molybdopterin cofactor binding
AOT18_04065	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AOT18_04070	COG3339	Conserved Protein
AOT18_04080	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AOT18_04095	COG1113	amino acid transport
AOT18_04105	COG0019	diaminopimelate decarboxylase activity
AOT18_04115	COG1280	lysine exporter protein (LysE YggA)
AOT18_04120	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AOT18_04150	COG0463	Glycosyl transferase, family 2
AOT18_04170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOT18_04200	COG4591	ABC-type transport system involved in lipoprotein release permease component
AOT18_04205	COG1136	(ABC) transporter
AOT18_04210	COG2333	competence protein COMEC
AOT18_04210	COG0658	competence protein
AOT18_04220	COG0616	signal peptide processing
AOT18_04220	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AOT18_04225	COG0596	Alpha beta hydrolase
AOT18_04230	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AOT18_04240	COG0628	permease
AOT18_04275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOT18_04295	COG0823	Involved in the tonB-independent uptake of proteins
AOT18_04315	COG0824	Thioesterase
AOT18_04320	COG1473	amidohydrolase
AOT18_04340	COG0047	phosphoribosylformylglycinamidine synthase activity
AOT18_04340	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AOT18_04345	COG2814	Major facilitator Superfamily
AOT18_04355	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AOT18_04360	COG1024	Enoyl-CoA hydratase
AOT18_04365	COG1056	cytidyltransferase-related domain
AOT18_04365	COG1051	belongs to the nudix hydrolase family
AOT18_04375	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AOT18_04390	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AOT18_04405	COG4625	pathogenesis
AOT18_04410	COG0583	DNA-binding transcription factor activity
AOT18_04415	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AOT18_04420	COG4208	sulfate ABC transporter
AOT18_04425	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AOT18_04435	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AOT18_04440	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AOT18_04445	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AOT18_04465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOT18_04480	COG0681	Belongs to the peptidase S26 family
AOT18_04495	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AOT18_04505	COG1381	Involved in DNA repair and RecF pathway recombination
AOT18_04510	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AOT18_04520	COG4221	oxidoreductase activity
AOT18_04565	COG0556	nucleotide-excision repair
AOT18_04620	COG2070	2-Nitropropane dioxygenase
AOT18_04650	COG1215	transferase activity, transferring glycosyl groups
AOT18_04665	COG0415	Belongs to the DNA photolyase family
AOT18_04675	COG1252	NADH dehydrogenase
AOT18_04680	COG1686	Belongs to the peptidase S11 family
AOT18_04695	COG1187	pseudouridine synthase activity
AOT18_04715	COG0477	Major facilitator Superfamily
AOT18_04720	COG0583	DNA-binding transcription factor activity
AOT18_04735	COG0612	Peptidase, M16
AOT18_04760	COG0352	thiamine-phosphate diphosphorylase activity
AOT18_04795	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOT18_04810	COG1309	transcriptional regulator
AOT18_04820	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AOT18_04825	COG0076	glutamate decarboxylase activity
AOT18_04835	COG1522	sequence-specific DNA binding
AOT18_04840	COG3961	Belongs to the TPP enzyme family
AOT18_04845	COG1113	amino acid transport
AOT18_04850	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AOT18_04855	COG0573	inorganic phosphate transmembrane transporter activity
AOT18_04865	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AOT18_04870	COG0616	signal peptide processing
AOT18_04905	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AOT18_04910	COG1686	Belongs to the peptidase S11 family
AOT18_04935	COG0583	DNA-binding transcription factor activity
AOT18_04940	COG1067	ATP-dependent peptidase activity
AOT18_04985	COG1966	Carbon starvation protein
AOT18_04990	COG2879	small protein
AOT18_05020	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AOT18_05020	COG2508	Transcriptional regulator
AOT18_05040	COG1113	amino acid transport
AOT18_05045	COG0583	DNA-binding transcription factor activity
AOT18_05050	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOT18_05055	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOT18_05070	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOT18_05075	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AOT18_05075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOT18_05110	COG2814	Major facilitator Superfamily
AOT18_05115	COG4948	Mandelate Racemase Muconate Lactonizing
AOT18_05125	COG1309	transcriptional regulator
AOT18_05140	COG1741	Belongs to the pirin family
AOT18_05150	COG2964	Protein conserved in bacteria
AOT18_05165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOT18_05170	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOT18_05175	COG4605	iron ion homeostasis
AOT18_05180	COG4604	ABC transporter, ATP-binding protein
AOT18_05185	COG4607	ABC-type enterochelin transport system periplasmic component
AOT18_05190	COG4774	siderophore transport
AOT18_05200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOT18_05205	COG1021	2,3-dihydroxybenzoate-AMP ligase
AOT18_05210	COG3433	isochorismatase activity
AOT18_05210	COG1535	isochorismatase
AOT18_05225	COG1132	(ABC) transporter
AOT18_05235	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AOT18_05245	COG1169	isochorismate synthase
AOT18_05260	COG3739	integral membrane protein
AOT18_05300	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AOT18_05330	COG0308	aminopeptidase N
AOT18_05335	COG0512	Glutamine amidotransferase of anthranilate synthase
AOT18_05345	COG3104	oligopeptide transport
AOT18_05360	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AOT18_05395	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AOT18_05400	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AOT18_05405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOT18_05425	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AOT18_05430	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AOT18_05435	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AOT18_05450	COG1960	acyl-CoA dehydrogenase activity
AOT18_05455	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AOT18_05460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOT18_05475	COG2223	nitrite transmembrane transporter activity
AOT18_05485	COG0024	Methionine aminopeptidase
AOT18_05490	COG0052	Belongs to the universal ribosomal protein uS2 family
AOT18_05505	COG2207	Transcriptional regulator
AOT18_05530	COG2951	lytic endotransglycosylase activity
AOT18_05535	COG0772	Belongs to the SEDS family
AOT18_05550	COG0842	Transport permease protein
AOT18_05555	COG1131	(ABC) transporter
AOT18_05590	COG1538	Outer membrane efflux protein
AOT18_05600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOT18_05615	COG4215	(ABC) transporter
AOT18_05620	COG4160	amino acid transport
AOT18_05625	COG4598	ABC transporter
AOT18_05635	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AOT18_05645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOT18_05660	COG1720	tRNA m6t6A37 methyltransferase activity
AOT18_05680	COG0745	RESPONSE REGULATOR receiver
AOT18_05685	COG0642	Histidine kinase
AOT18_05695	COG0494	nUDIX hydrolase
AOT18_05705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOT18_05710	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AOT18_05715	COG3139	Protein of unknown function (DUF1315)
AOT18_05720	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AOT18_05725	COG1301	dicarboxylic acid transport
AOT18_05730	COG1960	acyl-CoA dehydrogenase activity
AOT18_05735	COG2819	hydrolase of the alpha beta superfamily
AOT18_05745	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AOT18_05755	COG2195	Cleaves the N-terminal amino acid of tripeptides
AOT18_05760	COG1234	tRNA 3'-trailer cleavage
AOT18_05790	COG2363	Small membrane protein
AOT18_05810	COG0513	Belongs to the DEAD box helicase family
AOT18_05820	COG0778	Nitroreductase
AOT18_05850	COG1286	toxin biosynthetic process
AOT18_05875	COG4783	chaperone-mediated protein folding
AOT18_05880	COG1610	YqeY-like protein
AOT18_05885	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AOT18_05980	COG3111	PFAM Bacterial OB fold (BOF) protein
AOT18_06005	COG3243	poly(R)-hydroxyalkanoic acid synthase
AOT18_06010	COG0786	glutamate:sodium symporter activity
AOT18_06020	COG2186	Transcriptional regulator
AOT18_06080	COG0477	Major facilitator Superfamily
AOT18_06105	COG2985	domain, Protein
AOT18_06115	COG2995	paraquat-inducible protein a
AOT18_06120	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AOT18_06120	COG3008	intermembrane lipid transfer
AOT18_06130	COG1794	racemase activity, acting on amino acids and derivatives
AOT18_06150	COG3316	Transposase and inactivated derivatives
AOT18_06160	COG3316	Transposase and inactivated derivatives
AOT18_06230	COG3173	Aminoglycoside phosphotransferase
AOT18_06240	COG2433	Pfam Transposase IS66
AOT18_06265	COG3316	Transposase and inactivated derivatives
AOT18_06280	COG1301	dicarboxylic acid transport
AOT18_06290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOT18_06295	COG2011	ABC-type metal ion transport system permease component
AOT18_06300	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AOT18_06305	COG1464	Belongs to the NlpA lipoprotein family
AOT18_06310	COG0151	Belongs to the GarS family
AOT18_06315	COG0138	bifunctional purine biosynthesis protein purh
AOT18_06320	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AOT18_06350	COG2308	Evidence 4 Homologs of previously reported genes of
AOT18_06360	COG1305	Transglutaminase-like
AOT18_06370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AOT18_06375	COG0305	Participates in initiation and elongation during chromosome replication
AOT18_06400	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AOT18_06410	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AOT18_06415	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AOT18_06440	COG1649	PFAM Uncharacterised BCR, COG1649
AOT18_06440	COG0726	polysaccharide deacetylase
AOT18_06445	COG1215	transferase activity, transferring glycosyl groups
AOT18_06450	COG3658	cytochrome
AOT18_06460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOT18_06475	COG0583	DNA-binding transcription factor activity
AOT18_06495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOT18_06500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOT18_06515	COG1960	acyl-CoA dehydrogenase activity
AOT18_06520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOT18_06525	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOT18_06550	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AOT18_06555	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AOT18_06565	COG2205	protein histidine kinase activity
AOT18_06570	COG0745	RESPONSE REGULATOR receiver
AOT18_06575	COG0174	glutamine synthetase
AOT18_06595	COG0729	surface antigen
AOT18_06620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOT18_06625	COG2814	Major facilitator Superfamily
AOT18_06640	COG0583	DNA-binding transcription factor activity
AOT18_06655	COG1187	pseudouridine synthase activity
AOT18_06675	COG0802	atpase or kinase
AOT18_06680	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AOT18_06690	COG1923	regulation of RNA biosynthetic process
AOT18_06695	COG0697	spore germination
AOT18_06710	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AOT18_06725	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AOT18_06725	COG0519	Catalyzes the synthesis of GMP from XMP
AOT18_06730	COG4302	ethanolamine ammonia-lyase activity
AOT18_06735	COG4303	Ethanolamine ammonia lyase large subunit
AOT18_06740	COG0531	amino acid
AOT18_06760	COG1454	alcohol dehydrogenase
AOT18_06765	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AOT18_06775	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AOT18_06795	COG0308	aminopeptidase N
AOT18_06805	COG4221	oxidoreductase activity
AOT18_06815	COG1605	Chorismate mutase
AOT18_06830	COG1309	transcriptional regulator
AOT18_06840	COG0668	transmembrane transport
AOT18_06880	COG4773	Receptor
AOT18_06900	COG0488	(ABC) transporter
AOT18_06905	COG0589	response to stress
AOT18_06925	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AOT18_06935	COG3135	benzoate transporter
AOT18_06940	COG1522	sequence-specific DNA binding
AOT18_06955	COG0583	DNA-binding transcription factor activity
AOT18_06965	COG0183	Belongs to the thiolase family
AOT18_06995	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AOT18_07005	COG0824	Thioesterase
AOT18_07010	COG1454	alcohol dehydrogenase
AOT18_07020	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AOT18_07040	COG0069	glutamate synthase activity
AOT18_07325	COG1598	PFAM Uncharacterised protein family UPF0150
AOT18_07350	COG0739	heme binding
AOT18_07455	COG2814	Major facilitator Superfamily
AOT18_07470	COG0511	ligase activity, forming carbon-carbon bonds
AOT18_07485	COG1116	anion transmembrane transporter activity
AOT18_07485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOT18_07490	COG0745	RESPONSE REGULATOR receiver
AOT18_07500	COG2146	nitrite reductase [NAD(P)H] activity
AOT18_07500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOT18_07505	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOT18_07510	COG0243	molybdopterin cofactor binding
AOT18_07520	COG0243	molybdopterin cofactor binding
AOT18_07525	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AOT18_07540	COG0521	Mo-molybdopterin cofactor biosynthetic process
AOT18_07540	COG0315	cyclic pyranopterin monophosphate synthase activity
AOT18_07545	COG0303	'Molybdopterin
AOT18_07555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOT18_07560	COG0697	spore germination
AOT18_07580	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AOT18_07585	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOT18_07665	COG2204	response regulator
AOT18_07670	COG3852	Histidine kinase
AOT18_07690	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AOT18_07695	COG0575	Belongs to the CDS family
AOT18_07730	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AOT18_07745	COG2137	regulation of response to DNA damage stimulus
AOT18_07755	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AOT18_07760	COG1011	Hydrolase
AOT18_07785	COG1522	sequence-specific DNA binding
AOT18_07795	COG1113	amino acid transport
AOT18_07810	COG0659	secondary active sulfate transmembrane transporter activity
AOT18_07815	COG2135	peptidase activity
AOT18_07830	COG5001	Diguanylate cyclase
AOT18_07830	COG3300	MHYT domain
AOT18_07850	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AOT18_07850	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AOT18_07850	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AOT18_07855	COG1105	Belongs to the carbohydrate kinase PfkB family
AOT18_07860	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOT18_07860	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AOT18_07890	COG0024	Methionine aminopeptidase
AOT18_07895	COG0583	DNA-binding transcription factor activity
AOT18_07905	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AOT18_07910	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AOT18_07915	COG0516	GMP reductase activity
AOT18_07915	COG0517	IMP dehydrogenase activity
AOT18_07940	COG0552	protein localization to endoplasmic reticulum
AOT18_07950	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AOT18_07965	COG4890	Cyd operon protein YbgT
AOT18_07970	COG1294	oxidase, subunit
AOT18_07985	COG1585	Membrane protein implicated in regulation of membrane protease activity
AOT18_07995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOT18_08000	COG4774	siderophore transport
AOT18_08015	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AOT18_08020	COG0569	domain protein
AOT18_08025	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AOT18_08055	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AOT18_08060	COG0542	response to heat
AOT18_08070	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AOT18_08085	COG1902	pentaerythritol trinitrate reductase activity
AOT18_08085	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOT18_08130	COG2323	membrane
AOT18_08135	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AOT18_08145	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AOT18_08150	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AOT18_08155	COG0183	Belongs to the thiolase family
AOT18_08160	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AOT18_08165	COG0596	Alpha beta hydrolase
AOT18_08170	COG2271	Major facilitator Superfamily
AOT18_08175	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AOT18_08180	COG3485	protocatechuate 3,4-dioxygenase
AOT18_08185	COG3485	protocatechuate 3,4-dioxygenase
AOT18_08190	COG0710	3-dehydroquinate dehydratase activity
AOT18_08195	COG3420	alginic acid biosynthetic process
AOT18_08200	COG3659	wide pore channel activity
AOT18_08205	COG4993	Dehydrogenase
AOT18_08215	COG2391	methyltransferase activity
AOT18_08230	COG1414	Transcriptional regulator
AOT18_08235	COG0583	DNA-binding transcription factor activity
AOT18_08240	COG1960	acyl-CoA dehydrogenase activity
AOT18_08265	COG2814	Major facilitator Superfamily
AOT18_08275	COG0154	amidase activity
AOT18_08295	COG4638	Rieske (2fe-2S)
AOT18_08305	COG1028	Short-chain dehydrogenase reductase Sdr
AOT18_08315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOT18_08325	COG3733	amine oxidase
AOT18_08335	COG1012	belongs to the aldehyde dehydrogenase family
AOT18_08345	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOT18_08350	COG0183	Belongs to the thiolase family
AOT18_08355	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AOT18_08360	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AOT18_08370	COG4829	muconolactone delta-isomerase
AOT18_08375	COG4948	Mandelate Racemase Muconate Lactonizing
AOT18_08380	COG0583	DNA-binding transcription factor activity
AOT18_08390	COG2186	Transcriptional regulator
AOT18_08410	COG1012	belongs to the aldehyde dehydrogenase family
AOT18_08430	COG1960	acyl-CoA dehydrogenase activity
AOT18_08440	COG3829	transcription factor binding
AOT18_08450	COG3162	membrane
AOT18_08465	COG1012	belongs to the aldehyde dehydrogenase family
AOT18_08480	COG0753	catalase activity
AOT18_08505	COG1846	Transcriptional regulator
AOT18_08510	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOT18_08510	COG1902	pentaerythritol trinitrate reductase activity
AOT18_08520	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AOT18_08550	COG1309	transcriptional regulator
AOT18_08560	COG1335	isochorismatase
AOT18_08565	COG0583	DNA-binding transcription factor activity
AOT18_08575	COG0475	glutathione-regulated potassium exporter activity
AOT18_08575	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AOT18_08585	COG1473	amidohydrolase
AOT18_08595	COG2831	hemolysin activation secretion protein
AOT18_08600	COG3210	domain, Protein
AOT18_08660	COG0583	DNA-binding transcription factor activity
AOT18_08685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AOT18_08690	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AOT18_08710	COG1566	PFAM secretion protein HlyD family protein
AOT18_08725	COG1012	belongs to the aldehyde dehydrogenase family
AOT18_08730	COG0129	dihydroxy-acid dehydratase activity
AOT18_08740	COG0583	DNA-binding transcription factor activity
AOT18_08745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOT18_08755	COG2084	Dehydrogenase
AOT18_08760	COG2207	Transcriptional regulator
AOT18_08775	COG1064	alcohol dehydrogenase
AOT18_08790	COG1120	ATPase activity
AOT18_08810	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AOT18_08925	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AOT18_08975	COG1028	Short-chain dehydrogenase reductase Sdr
AOT18_08990	COG2207	Transcriptional regulator
AOT18_09000	COG2205	protein histidine kinase activity
AOT18_09005	COG0745	RESPONSE REGULATOR receiver
AOT18_09010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOT18_09015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOT18_09020	COG1538	Outer membrane efflux protein
AOT18_09030	COG2072	flavoprotein involved in K transport
AOT18_09050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOT18_09070	COG3539	Fimbrial protein
AOT18_09105	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AOT18_09115	COG0753	catalase activity
AOT18_09130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AOT18_09190	COG3433	isochorismatase activity
AOT18_09190	COG1535	isochorismatase
AOT18_09195	COG1028	Short-chain dehydrogenase reductase Sdr
AOT18_09200	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AOT18_09205	COG4149	molybdate abc transporter
AOT18_09210	COG0725	ABC transporter, periplasmic molybdate-binding protein
AOT18_09220	COG4638	Rieske (2fe-2S)
AOT18_09225	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AOT18_09230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOT18_09230	COG0543	2 iron, 2 sulfur cluster binding
AOT18_09245	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOT18_09255	COG1028	Short-chain dehydrogenase reductase Sdr
AOT18_09260	COG0412	Dienelactone hydrolase
AOT18_09270	COG2207	Transcriptional regulator
AOT18_09285	COG1028	Short-chain dehydrogenase reductase Sdr
AOT18_09290	COG2610	gluconate transmembrane transporter activity
AOT18_09300	COG0583	DNA-binding transcription factor activity
AOT18_09310	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AOT18_09315	COG2031	fatty acid transporter
AOT18_09320	COG0183	Belongs to the thiolase family
AOT18_09325	COG0583	DNA-binding transcription factor activity
AOT18_09330	COG0583	DNA-binding transcription factor activity
AOT18_09345	COG1027	Aspartate ammonia-lyase
AOT18_09355	COG0477	Major facilitator Superfamily
AOT18_09375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOT18_09380	COG4521	taurine ABC transporter
AOT18_09405	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AOT18_09410	COG1733	regulation of RNA biosynthetic process
AOT18_09415	COG3708	Transcriptional regulator
AOT18_09415	COG2207	Transcriptional regulator
AOT18_09430	COG0730	response to heat
AOT18_09440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOT18_09440	COG3453	Protein conserved in bacteria
AOT18_09450	COG3781	membrane
AOT18_09455	COG1063	alcohol dehydrogenase
AOT18_09465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOT18_09470	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOT18_09475	COG0022	dehydrogenase e1 component
AOT18_09480	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AOT18_09485	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AOT18_09500	COG3706	GGDEF domain
AOT18_09515	COG0133	tryptophan synthase activity
AOT18_09525	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOT18_09560	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AOT18_09585	COG2226	methyltransferase
AOT18_09640	COG0842	Transport permease protein
AOT18_09645	COG0842	Transport permease protein
AOT18_09650	COG1131	(ABC) transporter
AOT18_09665	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AOT18_09670	COG4773	Receptor
AOT18_09690	COG0730	response to heat
AOT18_09695	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AOT18_09715	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AOT18_09730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AOT18_09770	COG4264	IucA IucC family
AOT18_09775	COG4264	IucA IucC family
AOT18_09795	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AOT18_09810	COG1960	acyl-CoA dehydrogenase activity
AOT18_09815	COG1960	acyl-CoA dehydrogenase activity
AOT18_09820	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOT18_09825	COG2207	Transcriptional regulator
AOT18_09830	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AOT18_09835	COG0776	regulation of translation
AOT18_09860	COG0822	iron-sulfur transferase activity
AOT18_09865	COG0316	Belongs to the HesB IscA family
AOT18_09895	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AOT18_09915	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AOT18_09920	COG0702	epimerase
AOT18_09955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOT18_09965	COG0339	signal peptide processing
AOT18_10010	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AOT18_10015	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AOT18_10045	COG0776	regulation of translation
AOT18_10065	COG0590	tRNA wobble adenosine to inosine editing
AOT18_10095	COG2165	general secretion pathway protein
AOT18_10110	COG0084	hydrolase, TatD family'
AOT18_10130	COG1663	tetraacyldisaccharide 4'-kinase activity
AOT18_10135	COG1132	(ABC) transporter
AOT18_10145	COG0811	peptide transport
AOT18_10150	COG1475	DNA binding
AOT18_10155	COG1192	Involved in chromosome partitioning
AOT18_10165	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AOT18_10180	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AOT18_10185	COG0191	fructose-bisphosphate aldolase activity
AOT18_10205	COG0424	maF-like protein
AOT18_10210	COG2850	peptidyl-arginine hydroxylation
AOT18_10220	COG0640	Transcriptional regulator
AOT18_10230	COG3619	membrane
AOT18_10235	COG3122	Protein conserved in bacteria
AOT18_10240	COG1132	(ABC) transporter
AOT18_10260	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AOT18_10265	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOT18_10275	COG0506	proline dehydrogenase activity
AOT18_10275	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AOT18_10275	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AOT18_10280	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AOT18_10295	COG3698	Phosphodiester glycosidase
AOT18_10315	COG1765	OsmC-like protein
AOT18_10335	COG2353	YceI-like domain
AOT18_10345	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AOT18_10390	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AOT18_10390	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AOT18_10415	COG3539	Fimbrial protein
AOT18_10420	COG3121	Chaperone
AOT18_10445	COG0697	spore germination
AOT18_10455	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AOT18_10465	COG0583	DNA-binding transcription factor activity
AOT18_10485	COG1309	transcriptional regulator
AOT18_10500	COG1522	sequence-specific DNA binding
AOT18_10510	COG1126	abc transporter atp-binding protein
AOT18_10515	COG0765	amino acid transport
AOT18_10520	COG0765	amino acid transport
AOT18_10550	COG1464	Belongs to the NlpA lipoprotein family
AOT18_10560	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AOT18_10565	COG2011	ABC-type metal ion transport system permease component
AOT18_10570	COG0012	GTP binding
AOT18_10595	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AOT18_10635	COG0386	Belongs to the glutathione peroxidase family
AOT18_10645	COG0436	Aminotransferase
AOT18_10685	COG3634	alkyl hydroperoxide reductase activity
AOT18_10700	COG0583	DNA-binding transcription factor activity
AOT18_10705	COG0798	PFAM Bile acid sodium symporter
AOT18_10710	COG0640	Transcriptional regulator
AOT18_10725	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AOT18_10735	COG0583	DNA-binding transcription factor activity
AOT18_10745	COG1953	Uracil, thiamine, allantoin
AOT18_10755	COG2175	clavaminate synthase activity
AOT18_10760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOT18_10765	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AOT18_10770	COG4521	taurine ABC transporter
AOT18_10780	COG0477	Major facilitator Superfamily
AOT18_10800	COG1271	oxidase subunit
AOT18_10805	COG1294	oxidase, subunit
AOT18_10815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOT18_10835	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AOT18_10855	COG3052	prosthetic group binding
AOT18_10860	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AOT18_10870	COG2814	Major facilitator Superfamily
AOT18_10890	COG1346	cytolysis
AOT18_10900	COG0583	DNA-binding transcription factor activity
AOT18_10905	COG0625	glutathione transferase activity
AOT18_10910	COG0625	glutathione transferase activity
AOT18_10915	COG0583	DNA-binding transcription factor activity
AOT18_10930	COG1045	serine acetyltransferase
AOT18_10935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOT18_10940	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AOT18_10945	COG1280	lysine exporter protein (LysE YggA)
AOT18_10955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOT18_10960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOT18_10965	COG1126	abc transporter atp-binding protein
AOT18_10970	COG0765	amino acid transport
AOT18_10975	COG0765	amino acid transport
AOT18_10990	COG2205	protein histidine kinase activity
AOT18_10990	COG0784	Response regulator, receiver
AOT18_11010	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AOT18_11030	COG1028	Short-chain dehydrogenase reductase Sdr
AOT18_11080	COG0583	DNA-binding transcription factor activity
AOT18_11100	COG0318	PFAM AMP-dependent synthetase and ligase
AOT18_11105	COG1309	transcriptional regulator
AOT18_11110	COG1960	acyl-CoA dehydrogenase activity
AOT18_11115	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AOT18_11120	COG1024	Enoyl-CoA hydratase
AOT18_11135	COG0583	DNA-binding transcription factor activity
AOT18_11150	COG1960	acyl-CoA dehydrogenase activity
AOT18_11160	COG2814	Major facilitator Superfamily
AOT18_11170	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AOT18_11175	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AOT18_11180	COG2814	Major facilitator Superfamily
AOT18_11185	COG1960	acyl-CoA dehydrogenase activity
AOT18_11190	COG1024	Enoyl-CoA hydratase
AOT18_11195	COG1028	Short-chain dehydrogenase reductase Sdr
AOT18_11200	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOT18_11205	COG0183	Belongs to the thiolase family
AOT18_11215	COG2814	Major facilitator Superfamily
AOT18_11225	COG1024	Enoyl-CoA hydratase
AOT18_11240	COG1960	acyl-CoA dehydrogenase activity
AOT18_11245	COG2814	Major facilitator Superfamily
AOT18_11250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AOT18_11255	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AOT18_11270	COG3842	ATPase activity
AOT18_11275	COG1840	ABC-type Fe3 transport system, periplasmic component
AOT18_11285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOT18_11290	COG1414	Transcriptional regulator
AOT18_11300	COG0583	DNA-binding transcription factor activity
AOT18_11305	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AOT18_11310	COG1012	belongs to the aldehyde dehydrogenase family
AOT18_11320	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AOT18_11325	COG1012	belongs to the aldehyde dehydrogenase family
AOT18_11330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOT18_11335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOT18_11340	COG2267	carboxylic ester hydrolase activity
AOT18_11360	COG3038	cytochrome b561
AOT18_11365	COG0753	catalase activity
AOT18_11400	COG2050	protein possibly involved in aromatic compounds catabolism
AOT18_11410	COG3327	negative regulation of DNA-templated transcription, initiation
AOT18_11415	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AOT18_11420	COG0183	Belongs to the thiolase family
AOT18_11425	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOT18_11430	COG1024	Enoyl-CoA hydratase
AOT18_11435	COG1024	Enoyl-CoA hydratase
AOT18_11440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOT18_11445	COG2151	metal-sulfur cluster biosynthetic enzyme
AOT18_11450	COG3396	Phenylacetate-CoA oxygenase
AOT18_11455	COG3460	Phenylacetate-CoA oxygenase
AOT18_11460	COG3396	Phenylacetate-CoA oxygenase
AOT18_11465	COG1012	belongs to the aldehyde dehydrogenase family
AOT18_11465	COG2030	dehydratase
AOT18_11470	COG1760	l-serine dehydratase
AOT18_11475	COG0531	amino acid
AOT18_11480	COG1012	belongs to the aldehyde dehydrogenase family
AOT18_11495	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOT18_11505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOT18_11525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOT18_11535	COG0789	Transcriptional regulator
AOT18_11555	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AOT18_11570	COG2807	transmembrane transport
AOT18_11575	COG0590	tRNA wobble adenosine to inosine editing
AOT18_11585	COG0583	DNA-binding transcription factor activity
AOT18_11625	COG2885	chlorophyll binding
AOT18_11625	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AOT18_11690	COG1116	anion transmembrane transporter activity
AOT18_11695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOT18_11705	COG0864	Transcriptional regulator
AOT18_11720	COG1733	regulation of RNA biosynthetic process
AOT18_11725	COG2249	NAD(P)H dehydrogenase (quinone) activity
AOT18_11730	COG0439	Biotin carboxylase
AOT18_11745	COG1063	alcohol dehydrogenase
AOT18_11755	COG1309	transcriptional regulator
AOT18_11780	COG0038	chloride channel
AOT18_11785	COG4770	biotin carboxylase activity
AOT18_11805	COG1914	H( )-stimulated, divalent metal cation uptake system
AOT18_11810	COG0583	DNA-binding transcription factor activity
AOT18_11825	COG3209	COG3209 Rhs family protein
AOT18_11830	COG3501	Rhs element vgr protein
AOT18_11855	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOT18_11875	COG2814	Major facilitator Superfamily
AOT18_11885	COG1560	Kdo2-lipid A biosynthetic process
AOT18_11895	COG5006	permease, DMT superfamily
AOT18_11900	COG1522	sequence-specific DNA binding
AOT18_11915	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AOT18_11955	COG1538	Outer membrane efflux protein
AOT18_11960	COG1137	ATPase activity
AOT18_11965	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AOT18_11975	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AOT18_11980	COG0517	IMP dehydrogenase activity
AOT18_11980	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AOT18_12015	COG1733	regulation of RNA biosynthetic process
AOT18_12020	COG2814	Major facilitator Superfamily
AOT18_12050	COG1278	Cold shock
AOT18_12055	COG1280	lysine exporter protein (LysE YggA)
AOT18_12090	COG1570	exodeoxyribonuclease VII activity
AOT18_12140	COG0583	DNA-binding transcription factor activity
AOT18_12145	COG4638	Rieske (2fe-2S)
AOT18_12150	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AOT18_12155	COG0633	Ferredoxin
AOT18_12155	COG0543	2 iron, 2 sulfur cluster binding
AOT18_12160	COG1028	Short-chain dehydrogenase reductase Sdr
AOT18_12165	COG3135	benzoate transporter
AOT18_12170	COG2814	Major facilitator Superfamily
AOT18_12185	COG1643	Atp-dependent helicase
AOT18_12190	COG0450	alkyl hydroperoxide reductase
AOT18_12200	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AOT18_12210	COG3634	alkyl hydroperoxide reductase activity
AOT18_12230	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AOT18_12235	COG0625	glutathione transferase activity
AOT18_12245	COG2885	chlorophyll binding
AOT18_12305	COG1765	OsmC-like protein
AOT18_12325	COG0667	Aldo Keto reductase
AOT18_12340	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AOT18_12350	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AOT18_12370	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AOT18_12380	COG3038	cytochrome b561
AOT18_12385	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AOT18_12390	COG2252	PERMEase
AOT18_12400	COG2072	flavoprotein involved in K transport
AOT18_12415	COG1741	Belongs to the pirin family
AOT18_12420	COG1309	transcriptional regulator
AOT18_12430	COG0300	oxidoreductase activity
AOT18_12435	COG2072	flavoprotein involved in K transport
AOT18_12440	COG3316	Transposase and inactivated derivatives
AOT18_12460	COG3316	Transposase and inactivated derivatives
AOT18_12465	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AOT18_12475	COG3316	Transposase and inactivated derivatives
AOT18_12490	COG3316	Transposase and inactivated derivatives
AOT18_12495	COG1113	amino acid transport
AOT18_12515	COG1012	belongs to the aldehyde dehydrogenase family
AOT18_12535	COG0531	amino acid
AOT18_12545	COG1113	amino acid transport
AOT18_12590	COG3209	COG3209 Rhs family protein
AOT18_12595	COG3501	Rhs element vgr protein
AOT18_12615	COG4269	membrane
AOT18_12630	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOT18_12630	COG1902	pentaerythritol trinitrate reductase activity
AOT18_12640	COG2203	Gaf domain
AOT18_12640	COG5001	Diguanylate cyclase
AOT18_12640	COG3706	GGDEF domain
AOT18_12640	COG4251	negative regulation of phosphorylation
AOT18_12650	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AOT18_12670	COG4172	Belongs to the ABC transporter superfamily
AOT18_12675	COG4239	(ABC) transporter, permease
AOT18_12680	COG4174	ABC transporter (Permease)
AOT18_12690	COG0741	lytic transglycosylase activity
AOT18_12690	COG0741	lytic transglycosylase activity
AOT18_12690	COG1388	LysM domain
AOT18_12690	COG1388	LysM domain
AOT18_12695	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AOT18_12735	COG0583	DNA-binding transcription factor activity
AOT18_12740	COG1279	arginine transmembrane transporter activity
AOT18_12760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOT18_12765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOT18_12770	COG0006	proline dipeptidase activity
AOT18_12805	COG2194	sulfuric ester hydrolase activity
AOT18_12850	COG0739	heme binding
AOT18_13165	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AOT18_13190	COG3384	dioxygenase
AOT18_13200	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AOT18_13205	COG2878	Part of a membrane complex involved in electron transport
AOT18_13210	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AOT18_13230	COG0768	penicillin binding
AOT18_13235	COG0742	ribosomal rna small subunit methyltransferase
AOT18_13250	COG0830	nickel cation binding
AOT18_13260	COG0804	urea catabolic process
AOT18_13300	COG1253	flavin adenine dinucleotide binding
AOT18_13310	COG2851	Citrate transporter
AOT18_13355	COG1773	rubredoxin
AOT18_13360	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOT18_13370	COG0583	DNA-binding transcription factor activity
AOT18_13395	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AOT18_13400	COG4181	ATPase activity
AOT18_13445	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AOT18_13465	COG0306	phosphate transporter
AOT18_13475	COG3958	Transketolase
AOT18_13480	COG3959	Transketolase, thiamine diphosphate binding domain
AOT18_13485	COG2271	Major facilitator Superfamily
AOT18_13490	COG1028	Short-chain dehydrogenase reductase Sdr
AOT18_13495	COG0583	DNA-binding transcription factor activity
AOT18_13510	COG2223	nitrite transmembrane transporter activity
AOT18_13515	COG2207	Transcriptional regulator
AOT18_13520	COG2066	Belongs to the glutaminase family
AOT18_13525	COG0242	peptide deformylase activity
AOT18_13530	COG0477	Major facilitator Superfamily
AOT18_13540	COG0028	Belongs to the TPP enzyme family
AOT18_13555	COG1028	Short-chain dehydrogenase reductase Sdr
AOT18_13560	COG2267	carboxylic ester hydrolase activity
AOT18_13570	COG2271	Major facilitator Superfamily
AOT18_13575	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOT18_13585	COG1028	Short-chain dehydrogenase reductase Sdr
AOT18_13605	COG1414	Transcriptional regulator
AOT18_13620	COG1024	Enoyl-CoA hydratase
AOT18_13630	COG1215	transferase activity, transferring glycosyl groups
AOT18_13635	COG1649	PFAM Uncharacterised BCR, COG1649
AOT18_13635	COG0726	polysaccharide deacetylase
AOT18_13645	COG4681	YaeQ
AOT18_13655	COG0523	cobalamin synthesis protein
AOT18_13665	COG1607	acyl-coa hydrolase
AOT18_13675	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOT18_13680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOT18_13685	COG1309	transcriptional regulator
AOT18_13710	COG2040	homocysteine
AOT18_13715	COG0531	amino acid
AOT18_13740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOT18_13745	COG0477	Major facilitator Superfamily
AOT18_13860	COG0592	DNA-directed DNA polymerase activity
AOT18_13900	COG2026	Addiction module toxin, RelE StbE family
AOT18_14045	COG3755	Protein conserved in bacteria
AOT18_14090	COG1484	DNA-dependent DNA replication
AOT18_14180	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AOT18_14245	COG0405	Gamma-glutamyltransferase
AOT18_14250	COG2814	Major facilitator Superfamily
AOT18_14260	COG2050	protein possibly involved in aromatic compounds catabolism
AOT18_14275	COG1090	epimerase
AOT18_14295	COG0420	3'-5' exonuclease activity
AOT18_14320	COG0735	belongs to the Fur family
AOT18_14325	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AOT18_14350	COG0121	glutamine amidotransferase
AOT18_14365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOT18_14375	COG0210	DNA helicase
AOT18_14380	COG2885	chlorophyll binding
AOT18_14385	COG0204	Acyl-transferase
AOT18_14400	COG2894	cell division
AOT18_14425	COG1280	lysine exporter protein (LysE YggA)
AOT18_14430	COG1674	ftsk spoiiie
AOT18_14430	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AOT18_14435	COG0492	ferredoxin-NADP+ reductase activity
AOT18_14440	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AOT18_14450	COG0456	acetyltransferase
AOT18_14510	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AOT18_14510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOT18_14530	COG1012	belongs to the aldehyde dehydrogenase family
AOT18_14550	COG0473	3-isopropylmalate dehydrogenase activity
AOT18_14555	COG0583	DNA-binding transcription factor activity
AOT18_14575	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AOT18_14600	COG0564	pseudouridine synthase activity
AOT18_14610	COG0358	DNA primase activity
AOT18_14625	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AOT18_14650	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AOT18_14680	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AOT18_14690	COG0351	phosphomethylpyrimidine kinase
AOT18_14690	COG0352	thiamine-phosphate diphosphorylase activity
AOT18_14690	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AOT18_14695	COG1652	LysM domain
AOT18_14785	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AOT18_14815	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AOT18_14825	COG0351	phosphomethylpyrimidine kinase
AOT18_14825	COG0352	thiamine-phosphate diphosphorylase activity
AOT18_14825	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AOT18_14830	COG1652	LysM domain
AOT18_14855	COG1399	metal-binding, possibly nucleic acid-binding protein
AOT18_14860	COG3101	peptidyl-lysine hydroxylation
AOT18_14865	COG0009	L-threonylcarbamoyladenylate synthase
AOT18_14870	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AOT18_14875	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AOT18_14890	COG4106	trans-aconitate 2-methyltransferase activity
AOT18_14905	COG2226	methyltransferase
AOT18_14905	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOT18_14905	COG0596	Alpha beta hydrolase
AOT18_14910	COG1877	trehalose-phosphatase activity
AOT18_14915	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AOT18_14920	COG2223	nitrite transmembrane transporter activity
AOT18_14940	COG1196	nuclear chromosome segregation
AOT18_14950	COG0730	response to heat
AOT18_14965	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AOT18_14975	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AOT18_15025	COG0489	protein tyrosine kinase activity
AOT18_15035	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOT18_15035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOT18_15065	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AOT18_15070	COG2081	HI0933 family
AOT18_15080	COG0668	transmembrane transport
AOT18_15100	COG0583	DNA-binding transcription factor activity
AOT18_15120	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOT18_15125	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AOT18_15155	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AOT18_15190	COG2205	protein histidine kinase activity
AOT18_15195	COG0745	RESPONSE REGULATOR receiver
AOT18_15215	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOT18_15225	COG2205	protein histidine kinase activity
AOT18_15295	COG4993	Dehydrogenase
AOT18_15315	COG0384	phenazine biosynthesis protein PhzF
AOT18_15340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOT18_15345	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AOT18_15355	COG0583	DNA-binding transcription factor activity
AOT18_15375	COG1473	amidohydrolase
AOT18_15385	COG0583	DNA-binding transcription factor activity
AOT18_15400	COG0583	DNA-binding transcription factor activity
AOT18_15405	COG1053	succinate dehydrogenase
AOT18_15415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AOT18_15420	COG2814	Major facilitator Superfamily
AOT18_15425	COG1960	acyl-CoA dehydrogenase activity
AOT18_15430	COG0583	DNA-binding transcription factor activity
AOT18_15435	COG1063	alcohol dehydrogenase
AOT18_15465	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AOT18_15470	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AOT18_15475	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AOT18_15490	COG3667	copper resistance
AOT18_15495	COG2132	Multicopper oxidase
AOT18_15505	COG0561	phosphatase activity
AOT18_15510	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AOT18_15535	COG1214	PFAM Peptidase M22, glycoprotease
AOT18_15605	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AOT18_15615	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AOT18_15620	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AOT18_15625	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AOT18_15685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOT18_15695	COG1846	Transcriptional regulator
AOT18_15700	COG1764	response to oxidative stress
AOT18_15740	COG0037	tRNA processing
AOT18_15750	COG0248	Ppx GppA phosphatase
AOT18_15775	COG0072	phenylalanine-tRNA ligase activity
AOT18_15800	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AOT18_15815	COG1238	metal cluster binding
AOT18_15820	COG0625	glutathione transferase activity
AOT18_15835	COG0318	PFAM AMP-dependent synthetase and ligase
AOT18_15840	COG3028	Belongs to the UPF0307 family
AOT18_15845	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOT18_15865	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AOT18_15870	COG0617	tRNA 3'-terminal CCA addition
AOT18_15875	COG1555	photosystem II stabilization
AOT18_15880	COG3956	TIGRFAM MazG family protein
AOT18_15890	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AOT18_15910	COG5002	protein histidine kinase activity
AOT18_15910	COG2205	protein histidine kinase activity
AOT18_15910	COG0784	Response regulator, receiver
AOT18_15915	COG1024	Enoyl-CoA hydratase
AOT18_15920	COG2084	Dehydrogenase
AOT18_15925	COG3622	Belongs to the hyi family
AOT18_15940	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AOT18_15945	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AOT18_15950	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AOT18_15955	COG0697	spore germination
AOT18_15965	COG2814	Major facilitator Superfamily
AOT18_15970	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AOT18_15980	COG0583	DNA-binding transcription factor activity
AOT18_15985	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AOT18_16000	COG0084	hydrolase, TatD family'
AOT18_16015	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AOT18_16045	COG0440	acetolactate synthase activity
AOT18_16050	COG0028	Belongs to the TPP enzyme family
AOT18_16075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOT18_16080	COG0577	efflux transmembrane transporter activity
AOT18_16080	COG1136	(ABC) transporter
AOT18_16085	COG1538	Outer membrane efflux protein
AOT18_16100	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AOT18_16105	COG1162	GTPase activity
AOT18_16115	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AOT18_16135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AOT18_16140	COG1028	Short-chain dehydrogenase reductase Sdr
AOT18_16180	COG2986	histidine ammonia-lyase
AOT18_16195	COG0318	PFAM AMP-dependent synthetase and ligase
AOT18_16205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AOT18_16210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AOT18_16250	COG1426	Protein conserved in bacteria
AOT18_16285	COG0793	Belongs to the peptidase S41A family
AOT18_16300	COG2267	carboxylic ester hydrolase activity
AOT18_16310	COG1012	belongs to the aldehyde dehydrogenase family
AOT18_16315	COG3265	gluconokinase activity
AOT18_16325	COG0800	Aldolase
AOT18_16335	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AOT18_16340	COG0857	belongs to the CobB CobQ family
AOT18_16340	COG0280	phosphate acetyltransferase
AOT18_16345	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AOT18_16345	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AOT18_16365	COG0740	serine-type endopeptidase activity
AOT18_16375	COG4774	siderophore transport
AOT18_16385	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AOT18_16395	COG2813	Specifically methylates the guanine in position
AOT18_16395	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOT18_16495	COG0788	formyltetrahydrofolate deformylase activity
AOT18_16510	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AOT18_16515	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AOT18_16520	COG4651	solute:proton antiporter activity
AOT18_16520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AOT18_16540	COG0724	RNA recognition motif
AOT18_16545	COG0210	DNA helicase
AOT18_16570	COG1733	regulation of RNA biosynthetic process
AOT18_16590	COG1280	lysine exporter protein (LysE YggA)
AOT18_16595	COG1560	Kdo2-lipid A biosynthetic process
AOT18_16605	COG1301	dicarboxylic acid transport
AOT18_16660	COG0473	3-isopropylmalate dehydrogenase activity
AOT18_16725	COG0583	DNA-binding transcription factor activity
AOT18_16735	COG0625	glutathione transferase activity
AOT18_16740	COG2378	regulation of single-species biofilm formation
AOT18_16745	COG0546	phosphoglycolate phosphatase activity
AOT18_16755	COG1530	ribonuclease E activity
AOT18_16775	COG0583	DNA-binding transcription factor activity
AOT18_16780	COG4221	oxidoreductase activity
AOT18_16785	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AOT18_16795	COG0534	Mate efflux family protein
AOT18_16810	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOT18_16845	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AOT18_16850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOT18_16865	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AOT18_16875	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AOT18_16875	COG0644	oxidoreductase
AOT18_16880	COG0425	Belongs to the sulfur carrier protein TusA family
AOT18_16885	COG4535	Mg2 and Co2 transporter CorC
AOT18_16895	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOT18_16915	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AOT18_16920	COG0475	glutathione-regulated potassium exporter activity
AOT18_16920	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AOT18_16925	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AOT18_16935	COG0484	heat shock protein binding
AOT18_16940	COG0789	Transcriptional regulator
AOT18_16945	COG0598	Magnesium transport protein CorA
AOT18_16965	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AOT18_16970	COG1074	ATP-dependent DNA helicase activity
AOT18_16975	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AOT18_16995	COG2226	methyltransferase
AOT18_17010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOT18_17015	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AOT18_17030	COG2111	Na H antiporter
AOT18_17030	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AOT18_17035	COG1006	Multisubunit Na H antiporter MnhC subunit
AOT18_17040	COG0651	ATP synthesis coupled electron transport
AOT18_17050	COG2212	antiporter activity
AOT18_17070	COG0195	Participates in both transcription termination and antitermination
AOT18_17120	COG0237	dephospho-CoA kinase activity
AOT18_17130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOT18_17145	COG0497	DNA recombination
AOT18_17155	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AOT18_17185	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AOT18_17185	COG2169	Transcriptional regulator
AOT18_17190	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AOT18_17255	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AOT18_17270	COG0326	Molecular chaperone. Has ATPase activity
AOT18_17285	COG2056	Na+-H+ antiporter family
AOT18_17290	COG0596	Alpha beta hydrolase
AOT18_17385	COG0546	phosphoglycolate phosphatase activity
AOT18_17390	COG1716	ATPase activity
AOT18_17435	COG0181	hydroxymethylbilane synthase activity
AOT18_17445	COG3275	phosphorelay sensor kinase activity
AOT18_17465	COG1538	Outer membrane efflux protein
AOT18_17470	COG0697	spore germination
AOT18_17495	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AOT18_17500	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AOT18_17505	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AOT18_17510	COG0772	Belongs to the SEDS family
AOT18_17535	COG4974	Belongs to the 'phage' integrase family
AOT18_17540	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AOT18_17550	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AOT18_17560	COG2197	response regulator
AOT18_17575	COG0793	Belongs to the peptidase S41A family
AOT18_17580	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AOT18_17585	COG0795	lipopolysaccharide-transporting ATPase activity
AOT18_17625	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AOT18_17625	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AOT18_17635	COG0004	ammonium transporteR
AOT18_17640	COG0347	Belongs to the P(II) protein family
AOT18_17700	COG0659	secondary active sulfate transmembrane transporter activity
AOT18_17705	COG0589	response to stress
AOT18_17745	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOT18_17795	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AOT18_17825	COG0659	secondary active sulfate transmembrane transporter activity
AOT18_17830	COG0589	response to stress
AOT18_17865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOT18_17875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOT18_17890	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AOT18_17905	COG0318	PFAM AMP-dependent synthetase and ligase
AOT18_17915	COG0477	Major facilitator Superfamily
AOT18_17920	COG2860	membrane
AOT18_17930	COG1253	flavin adenine dinucleotide binding
AOT18_17950	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AOT18_17985	COG0655	NAD(P)H dehydrogenase (quinone) activity
AOT18_17995	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AOT18_18030	COG1309	transcriptional regulator
AOT18_18065	COG0758	DNA mediated transformation
AOT18_18075	COG0697	spore germination
AOT18_18080	COG1309	transcriptional regulator
AOT18_18095	COG0386	Belongs to the glutathione peroxidase family
AOT18_18160	COG1121	(ABC) transporter
AOT18_18165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AOT18_18170	COG1280	lysine exporter protein (LysE YggA)
AOT18_18175	COG2837	iron assimilation
AOT18_18185	COG0281	malic enzyme
AOT18_18230	COG0519	Catalyzes the synthesis of GMP from XMP
AOT18_18230	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AOT18_18235	COG4399	Belongs to the UPF0754 family
AOT18_18240	COG2259	Doxx family
AOT18_18245	COG0586	Pfam SNARE associated Golgi protein
AOT18_18260	COG1192	Involved in chromosome partitioning
AOT18_18270	COG0271	Belongs to the BolA IbaG family
AOT18_18290	COG2267	carboxylic ester hydrolase activity
AOT18_18305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOT18_18315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AOT18_18315	COG3321	synthase
AOT18_18315	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AOT18_18315	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOT18_18320	COG1960	acyl-CoA dehydrogenase activity
AOT18_18330	COG2197	response regulator
AOT18_18340	COG3916	Acyl-homoserine-lactone synthase
AOT18_18345	COG0477	Major facilitator Superfamily
AOT18_18350	COG1024	Enoyl-CoA hydratase
AOT18_18355	COG1024	Enoyl-CoA hydratase
AOT18_18360	COG1960	acyl-CoA dehydrogenase activity
AOT18_18385	COG1113	amino acid transport
AOT18_18390	COG1113	amino acid transport
AOT18_18395	COG0251	oxidation-reduction process
AOT18_18410	COG1522	sequence-specific DNA binding
AOT18_18435	COG0564	pseudouridine synthase activity
AOT18_18485	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AOT18_18500	COG1802	Transcriptional regulator
AOT18_18505	COG1448	Aminotransferase
AOT18_18510	COG0277	FAD linked oxidase domain protein
AOT18_18520	COG2186	Transcriptional regulator
AOT18_18530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOT18_18535	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOT18_18550	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AOT18_18555	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AOT18_18560	COG1216	Glycosyl transferase, family 2
AOT18_18590	COG2089	acid synthase
AOT18_18605	COG1083	cytidylyl-transferase
AOT18_18610	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AOT18_18615	COG1086	Polysaccharide biosynthesis protein
AOT18_18620	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AOT18_18625	COG1596	polysaccharide export
AOT18_18650	COG0728	peptidoglycan biosynthetic process
AOT18_18655	COG3023	N-Acetylmuramoyl-L-alanine amidase
AOT18_18710	COG0546	phosphoglycolate phosphatase activity
AOT18_18715	COG1028	Short-chain dehydrogenase reductase Sdr
AOT18_18735	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOT18_18740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOT18_18745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOT18_18750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOT18_18755	COG1116	anion transmembrane transporter activity
AOT18_18760	COG1309	transcriptional regulator
AOT18_18765	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AOT18_18775	COG0196	riboflavin kinase activity
AOT18_18780	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AOT18_18790	COG1047	Peptidyl-prolyl cis-trans
AOT18_18830	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AOT18_18855	COG0583	DNA-binding transcription factor activity
AOT18_18885	COG2951	lytic endotransglycosylase activity
AOT18_18890	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AOT18_18905	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AOT18_18915	COG0671	phosphoesterase, PA-phosphatase related
AOT18_18920	COG0861	Integral membrane protein TerC family
AOT18_18930	COG0754	glutathionylspermidine amidase activity
AOT18_18940	COG0402	S-adenosylhomocysteine deaminase activity
AOT18_18960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AOT18_18965	COG1230	cation diffusion facilitator family transporter
AOT18_18980	COG0706	membrane insertase activity
AOT18_18995	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AOT18_19005	COG2130	NADP-dependent
AOT18_19050	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AOT18_19085	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOT18_19090	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AOT18_19090	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOT18_19140	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AOT18_19140	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AOT18_19155	COG0587	DNA-directed DNA polymerase activity
AOT18_19200	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AOT18_19225	COG0194	GDP metabolic process
AOT18_19255	COG0358	DNA primase activity
AOT18_19435	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AOT18_19455	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AOT18_19470	COG1388	LysM domain
AOT18_19535	COG1063	alcohol dehydrogenase
AOT18_19565	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AOT18_19575	COG1979	alcohol dehydrogenase
AOT18_19585	COG1902	pentaerythritol trinitrate reductase activity
AOT18_19595	COG1309	transcriptional regulator
AOT18_19645	COG2826	transposase and inactivated derivatives, IS30 family
AOT18_19670	COG0741	lytic transglycosylase activity
AOT18_19700	COG2826	transposase and inactivated derivatives, IS30 family
AOT18_19720	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AOT18_19800	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AOT18_19870	COG1525	nuclease
AOT18_19955	COG1475	DNA binding
AOT18_19975	COG3853	Toxic anion resistance protein (TelA)
AOT18_20070	COG0484	heat shock protein binding