locus-tag	class	description
KU204_00010	COG0592	DNA-directed DNA polymerase activity
KU204_00020	COG0187	DNA topoisomerase II activity
KU204_00030	COG0586	Pfam SNARE associated Golgi protein
KU204_00035	COG0488	(ABC) transporter
KU204_00060	COG0596	Alpha beta hydrolase
KU204_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KU204_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KU204_00110	COG0733	neurotransmitter:sodium symporter activity
KU204_00150	COG2233	PERMEase
KU204_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU204_00200	COG2814	Major facilitator Superfamily
KU204_00205	COG0656	L-ascorbic acid biosynthetic process
KU204_00210	COG0583	DNA-binding transcription factor activity
KU204_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU204_00230	COG1064	alcohol dehydrogenase
KU204_00235	COG2818	Glycosylase
KU204_00250	COG1194	a g-specific adenine glycosylase
KU204_00270	COG2983	Belongs to the UPF0260 family
KU204_00275	COG2133	pyrroloquinoline quinone binding
KU204_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KU204_00285	COG2116	formate transmembrane transporter activity
KU204_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU204_00310	COG1335	isochorismatase
KU204_00315	COG0385	Bile acid
KU204_00320	COG0534	Mate efflux family protein
KU204_00325	COG1683	Conserved Protein
KU204_00345	COG0625	glutathione transferase activity
KU204_00355	COG1113	amino acid transport
KU204_00365	COG0523	cobalamin synthesis protein
KU204_00375	COG2188	Transcriptional regulator
KU204_00405	COG0010	Belongs to the arginase family
KU204_00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KU204_00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KU204_00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KU204_00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KU204_00540	COG0534	Mate efflux family protein
KU204_00545	COG0436	Aminotransferase
KU204_00550	COG2733	membrane
KU204_00565	COG2918	glutathione biosynthetic process
KU204_00580	COG1388	LysM domain
KU204_00580	COG0791	NLP P60 protein
KU204_00595	COG3150	esterase
KU204_00605	COG1028	Short-chain dehydrogenase reductase Sdr
KU204_00610	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
KU204_00620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU204_00630	COG2233	PERMEase
KU204_00635	COG2351	hydroxyisourate hydrolase activity
KU204_00670	COG3706	GGDEF domain
KU204_00685	COG1393	Belongs to the ArsC family
KU204_00690	COG0708	Exodeoxyribonuclease III
KU204_00710	COG0189	ligase activity
KU204_00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KU204_00740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KU204_00755	COG4942	peptidase
KU204_00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
KU204_00775	COG2119	membrane
KU204_00795	COG0426	domain, Protein
KU204_00795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU204_00820	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KU204_00840	COG1902	pentaerythritol trinitrate reductase activity
KU204_00845	COG1519	Transferase
KU204_00850	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KU204_00855	COG0668	transmembrane transport
KU204_00865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KU204_00870	COG1335	isochorismatase
KU204_00875	COG1522	sequence-specific DNA binding
KU204_00880	COG3328	transposase activity
KU204_00905	COG0784	Response regulator, receiver
KU204_00905	COG2198	Histidine kinase
KU204_00905	COG2205	protein histidine kinase activity
KU204_00910	COG3162	membrane
KU204_00915	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KU204_00925	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU204_00945	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KU204_00950	COG1309	transcriptional regulator
KU204_00970	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KU204_00970	COG0352	thiamine-phosphate diphosphorylase activity
KU204_00970	COG0351	phosphomethylpyrimidine kinase
KU204_00980	COG2814	Major facilitator Superfamily
KU204_00995	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KU204_01005	COG1113	amino acid transport
KU204_01015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KU204_01020	COG1012	belongs to the aldehyde dehydrogenase family
KU204_01030	COG1335	isochorismatase
KU204_01060	COG2814	Major facilitator Superfamily
KU204_01065	COG0583	DNA-binding transcription factor activity
KU204_01085	COG0667	Aldo Keto reductase
KU204_01120	COG1733	regulation of RNA biosynthetic process
KU204_01125	COG2249	NAD(P)H dehydrogenase (quinone) activity
KU204_01190	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KU204_01205	COG2329	Antibiotic biosynthesis monooxygenase
KU204_01235	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KU204_01265	COG0427	acetyl-CoA hydrolase
KU204_01290	COG0659	secondary active sulfate transmembrane transporter activity
KU204_01295	COG4221	oxidoreductase activity
KU204_01300	COG2873	o-acetylhomoserine
KU204_01305	COG0488	(ABC) transporter
KU204_01390	COG0833	amino acid
KU204_01435	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KU204_01440	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KU204_01455	COG2226	methyltransferase
KU204_01505	COG0070	glutamate synthase
KU204_01505	COG0069	glutamate synthase activity
KU204_01505	COG0067	glutamate synthase
KU204_01510	COG0493	'glutamate synthase
KU204_01520	COG1704	LemA family
KU204_01525	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KU204_01545	COG3307	-O-antigen
KU204_01565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KU204_01580	COG0194	GDP metabolic process
KU204_01630	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KU204_01650	COG5380	lipid catabolic process
KU204_01655	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KU204_01680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KU204_01685	COG0277	FAD linked oxidase domain protein
KU204_01695	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KU204_01700	COG2249	NAD(P)H dehydrogenase (quinone) activity
KU204_01715	COG1289	transmembrane transporter activity
KU204_01725	COG0628	permease
KU204_01730	COG1192	Involved in chromosome partitioning
KU204_01760	COG0833	amino acid
KU204_01765	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KU204_01770	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KU204_01780	COG1012	belongs to the aldehyde dehydrogenase family
KU204_01820	COG0583	DNA-binding transcription factor activity
KU204_01865	COG0517	IMP dehydrogenase activity
KU204_01870	COG1983	PspC domain protein
KU204_01880	COG1960	acyl-CoA dehydrogenase activity
KU204_01895	COG0408	coproporphyrinogen oxidase activity
KU204_01915	COG0513	Belongs to the DEAD box helicase family
KU204_01925	COG1127	ABC transporter
KU204_01930	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KU204_01940	COG2854	intermembrane phospholipid transfer
KU204_01950	COG0598	Magnesium transport protein CorA
KU204_01960	COG0494	nUDIX hydrolase
KU204_01965	COG1040	competence protein
KU204_01970	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KU204_01990	COG1946	Acyl-CoA thioesterase
KU204_01995	COG1301	dicarboxylic acid transport
KU204_02010	COG1959	2 iron, 2 sulfur cluster binding
KU204_02015	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU204_02015	COG1017	nitric oxide dioxygenase activity
KU204_02020	COG0433	COG0433 Predicted ATPase
KU204_02025	COG0626	cystathionine gamma-synthase activity
KU204_02180	COG1960	acyl-CoA dehydrogenase activity
KU204_02185	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KU204_02215	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KU204_02220	COG0339	signal peptide processing
KU204_02225	COG0557	exoribonuclease II activity
KU204_02270	COG0179	Fumarylacetoacetate (FAA) hydrolase
KU204_02275	COG2169	Transcriptional regulator
KU204_02280	COG0697	spore germination
KU204_02285	COG1295	ribonuclease BN
KU204_02320	COG1702	phosphate starvation-inducible protein PhoH
KU204_02330	COG0739	heme binding
KU204_02330	COG1196	nuclear chromosome segregation
KU204_02330	COG0741	lytic transglycosylase activity
KU204_02360	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KU204_02365	COG1183	phosphatidylcholine synthase activity
KU204_02410	COG1960	acyl-CoA dehydrogenase activity
KU204_02415	COG1309	transcriptional regulator
KU204_02430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KU204_02435	COG1960	acyl-CoA dehydrogenase activity
KU204_02455	COG2969	positive regulation of protein catabolic process
KU204_02465	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KU204_02480	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KU204_02485	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KU204_02505	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KU204_02515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KU204_02520	COG1408	metallophosphoesterase
KU204_02530	COG2199	diguanylate cyclase activity
KU204_02590	COG1607	acyl-coa hydrolase
KU204_02620	COG2350	Protein conserved in bacteria
KU204_02630	COG0613	PHP domain protein
KU204_02635	COG3781	membrane
KU204_02645	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KU204_02650	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KU204_02660	COG1862	Preprotein translocase
KU204_02690	COG2205	protein histidine kinase activity
KU204_02695	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KU204_02715	COG0726	polysaccharide deacetylase
KU204_02720	COG0463	Glycosyl transferase, family 2
KU204_02725	COG0438	transferase activity, transferring glycosyl groups
KU204_02790	COG0625	glutathione transferase activity
KU204_02795	COG0583	DNA-binding transcription factor activity
KU204_02800	COG1960	acyl-CoA dehydrogenase activity
KU204_02805	COG1960	acyl-CoA dehydrogenase activity
KU204_02815	COG2205	protein histidine kinase activity
KU204_02820	COG0745	RESPONSE REGULATOR receiver
KU204_02825	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KU204_02845	COG2096	Adenosyltransferase
KU204_02895	COG0285	dihydrofolate synthase activity
KU204_02915	COG0450	alkyl hydroperoxide reductase
KU204_02930	COG0477	Major facilitator Superfamily
KU204_02935	COG1272	protein, Hemolysin III
KU204_02965	COG0183	Belongs to the thiolase family
KU204_02970	COG2207	Transcriptional regulator
KU204_02990	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU204_03010	COG0183	Belongs to the thiolase family
KU204_03020	COG2885	chlorophyll binding
KU204_03020	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KU204_03030	COG1690	Belongs to the RtcB family
KU204_03035	COG0833	amino acid
KU204_03045	COG2233	PERMEase
KU204_03050	COG1217	gtp-binding protein TYPA
KU204_03075	COG2094	Belongs to the DNA glycosylase MPG family
KU204_03080	COG4772	TonB-dependent receptor
KU204_03095	COG1902	pentaerythritol trinitrate reductase activity
KU204_03110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KU204_03115	COG0354	folic acid binding
KU204_03125	COG3189	MarR family transcriptional regulator
KU204_03130	COG2824	Alkylphosphonate utilization operon protein PhnA
KU204_03135	COG3422	double-strand break repair
KU204_03175	COG0840	transmembrane signaling receptor activity
KU204_03195	COG5510	response to toxic substance
KU204_03205	COG2832	Protein of unknown function (DUF454)
KU204_03210	COG1376	ErfK ybiS ycfS ynhG family protein
KU204_03250	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KU204_03260	COG1289	transmembrane transporter activity
KU204_03265	COG2814	Major facilitator Superfamily
KU204_03285	COG1115	amino acid carrier protein
KU204_03290	COG1752	Esterase of the alpha-beta hydrolase superfamily
KU204_03295	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KU204_03300	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
KU204_03340	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KU204_03350	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KU204_03355	COG1077	Cell shape determining protein MreB Mrl
KU204_03360	COG1792	Involved in formation and maintenance of cell shape
KU204_03365	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KU204_03370	COG0424	maF-like protein
KU204_03375	COG1530	ribonuclease E activity
KU204_03385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KU204_03395	COG0560	Phosphoserine phosphatase
KU204_03405	COG2249	NAD(P)H dehydrogenase (quinone) activity
KU204_03430	COG2207	Transcriptional regulator
KU204_03450	COG1113	amino acid transport
KU204_03455	COG2828	Protein conserved in bacteria
KU204_03460	COG0142	geranyltranstransferase activity
KU204_03465	COG2315	Protein conserved in bacteria
KU204_03480	COG1752	Esterase of the alpha-beta hydrolase superfamily
KU204_03500	COG2194	sulfuric ester hydrolase activity
KU204_03505	COG0745	RESPONSE REGULATOR receiver
KU204_03510	COG0642	Histidine kinase
KU204_03520	COG0004	ammonium transporteR
KU204_03525	COG0583	DNA-binding transcription factor activity
KU204_03545	COG0525	valine-tRNA ligase activity
KU204_03555	COG1028	Short-chain dehydrogenase reductase Sdr
KU204_03565	COG0393	Putative heavy-metal-binding
KU204_03570	COG0393	Putative heavy-metal-binding
KU204_03575	COG1538	Outer membrane efflux protein
KU204_03585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU204_03590	COG0671	phosphoesterase, PA-phosphatase related
KU204_03620	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KU204_03635	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KU204_03635	COG1648	precorrin-2 dehydrogenase activity
KU204_03640	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KU204_03645	COG1733	regulation of RNA biosynthetic process
KU204_03655	COG0531	amino acid
KU204_03670	COG0321	lipoyl(octanoyl) transferase activity
KU204_03675	COG2921	Belongs to the UPF0250 family
KU204_03715	COG2009	succinate dehydrogenase
KU204_03720	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KU204_03725	COG1053	succinate dehydrogenase
KU204_03730	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KU204_03755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KU204_03775	COG2354	Protein conserved in bacteria
KU204_03780	COG2321	neutral zinc metallopeptidase
KU204_03820	COG2843	Capsule synthesis protein
KU204_03835	COG0589	response to stress
KU204_03855	COG0505	Belongs to the CarA family
KU204_03880	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KU204_03885	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KU204_03935	COG0477	Major facilitator Superfamily
KU204_03940	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KU204_03955	COG1597	lipid kinase activity
KU204_03960	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KU204_03990	COG0584	glycerophosphoryl diester phosphodiesterase
KU204_04010	COG0741	lytic transglycosylase activity
KU204_04030	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KU204_04045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KU204_04070	COG0778	Nitroreductase
KU204_04085	COG1929	Belongs to the glycerate kinase type-1 family
KU204_04090	COG0243	molybdopterin cofactor binding
KU204_04095	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KU204_04100	COG3339	Conserved Protein
KU204_04110	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KU204_04125	COG1113	amino acid transport
KU204_04135	COG0019	diaminopimelate decarboxylase activity
KU204_04145	COG1280	lysine exporter protein (LysE YggA)
KU204_04150	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KU204_04180	COG0463	Glycosyl transferase, family 2
KU204_04200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU204_04235	COG4591	ABC-type transport system involved in lipoprotein release permease component
KU204_04240	COG1136	(ABC) transporter
KU204_04245	COG0658	competence protein
KU204_04245	COG2333	competence protein COMEC
KU204_04255	COG0616	signal peptide processing
KU204_04255	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KU204_04260	COG0596	Alpha beta hydrolase
KU204_04265	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KU204_04275	COG0628	permease
KU204_04310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KU204_04330	COG0823	Involved in the tonB-independent uptake of proteins
KU204_04350	COG0824	Thioesterase
KU204_04355	COG1473	amidohydrolase
KU204_04375	COG0047	phosphoribosylformylglycinamidine synthase activity
KU204_04375	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KU204_04380	COG2814	Major facilitator Superfamily
KU204_04390	COG1024	Enoyl-CoA hydratase
KU204_04395	COG1051	belongs to the nudix hydrolase family
KU204_04395	COG1056	cytidyltransferase-related domain
KU204_04405	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KU204_04420	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KU204_04435	COG4625	pathogenesis
KU204_04440	COG0583	DNA-binding transcription factor activity
KU204_04445	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KU204_04450	COG4208	sulfate ABC transporter
KU204_04455	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KU204_04465	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KU204_04470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KU204_04475	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KU204_04495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KU204_04510	COG0681	Belongs to the peptidase S26 family
KU204_04525	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KU204_04535	COG1381	Involved in DNA repair and RecF pathway recombination
KU204_04540	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KU204_04550	COG4221	oxidoreductase activity
KU204_04580	COG0436	Aminotransferase
KU204_04600	COG0556	nucleotide-excision repair
KU204_04655	COG2070	2-Nitropropane dioxygenase
KU204_04685	COG1215	transferase activity, transferring glycosyl groups
KU204_04700	COG0415	Belongs to the DNA photolyase family
KU204_04710	COG1252	NADH dehydrogenase
KU204_04715	COG1686	Belongs to the peptidase S11 family
KU204_04730	COG1187	pseudouridine synthase activity
KU204_04755	COG0477	Major facilitator Superfamily
KU204_04760	COG0583	DNA-binding transcription factor activity
KU204_04765	COG1823	symporter activity
KU204_04775	COG0612	Peptidase, M16
KU204_04800	COG0352	thiamine-phosphate diphosphorylase activity
KU204_04835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU204_04850	COG1309	transcriptional regulator
KU204_04860	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KU204_04865	COG0076	glutamate decarboxylase activity
KU204_04875	COG1522	sequence-specific DNA binding
KU204_04880	COG3961	Belongs to the TPP enzyme family
KU204_04885	COG1113	amino acid transport
KU204_04890	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KU204_04895	COG0573	inorganic phosphate transmembrane transporter activity
KU204_04905	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KU204_04910	COG0616	signal peptide processing
KU204_04920	COG3328	transposase activity
KU204_04950	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KU204_04955	COG1686	Belongs to the peptidase S11 family
KU204_04980	COG0583	DNA-binding transcription factor activity
KU204_04985	COG1067	ATP-dependent peptidase activity
KU204_05030	COG1966	Carbon starvation protein
KU204_05035	COG2879	small protein
KU204_05065	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KU204_05065	COG2508	Transcriptional regulator
KU204_05085	COG1113	amino acid transport
KU204_05090	COG0583	DNA-binding transcription factor activity
KU204_05095	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU204_05100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU204_05110	COG1012	belongs to the aldehyde dehydrogenase family
KU204_05115	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU204_05120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KU204_05120	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KU204_05155	COG2814	Major facilitator Superfamily
KU204_05160	COG4948	Mandelate Racemase Muconate Lactonizing
KU204_05170	COG1309	transcriptional regulator
KU204_05190	COG1741	Belongs to the pirin family
KU204_05200	COG2964	Protein conserved in bacteria
KU204_05215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KU204_05220	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KU204_05225	COG4605	iron ion homeostasis
KU204_05230	COG4604	ABC transporter, ATP-binding protein
KU204_05235	COG4607	ABC-type enterochelin transport system periplasmic component
KU204_05240	COG4774	siderophore transport
KU204_05250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KU204_05255	COG1021	2,3-dihydroxybenzoate-AMP ligase
KU204_05260	COG1535	isochorismatase
KU204_05260	COG3433	isochorismatase activity
KU204_05275	COG1132	(ABC) transporter
KU204_05280	COG1132	(ABC) transporter
KU204_05285	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KU204_05295	COG1169	isochorismate synthase
KU204_05310	COG3739	integral membrane protein
KU204_05335	COG0302	gtp cyclohydrolase
KU204_05345	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KU204_05375	COG0308	aminopeptidase N
KU204_05380	COG0512	Glutamine amidotransferase of anthranilate synthase
KU204_05395	COG0174	glutamine synthetase
KU204_05405	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KU204_05440	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KU204_05445	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KU204_05450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KU204_05470	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KU204_05475	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KU204_05480	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KU204_05495	COG1960	acyl-CoA dehydrogenase activity
KU204_05500	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KU204_05505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KU204_05515	COG2223	nitrite transmembrane transporter activity
KU204_05525	COG0024	Methionine aminopeptidase
KU204_05530	COG0052	Belongs to the universal ribosomal protein uS2 family
KU204_05545	COG2207	Transcriptional regulator
KU204_05570	COG2951	lytic endotransglycosylase activity
KU204_05575	COG0772	Belongs to the SEDS family
KU204_05590	COG0842	Transport permease protein
KU204_05595	COG1131	(ABC) transporter
KU204_05640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU204_05655	COG4215	(ABC) transporter
KU204_05660	COG4160	amino acid transport
KU204_05665	COG4598	ABC transporter
KU204_05675	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KU204_05680	COG0826	peptidase U32
KU204_05685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU204_05700	COG1720	tRNA m6t6A37 methyltransferase activity
KU204_05710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KU204_05725	COG0642	Histidine kinase
KU204_05735	COG0494	nUDIX hydrolase
KU204_05745	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KU204_05750	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KU204_05755	COG3139	Protein of unknown function (DUF1315)
KU204_05760	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KU204_05765	COG1301	dicarboxylic acid transport
KU204_05770	COG1960	acyl-CoA dehydrogenase activity
KU204_05775	COG2819	hydrolase of the alpha beta superfamily
KU204_05785	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KU204_05795	COG2195	Cleaves the N-terminal amino acid of tripeptides
KU204_05800	COG1234	tRNA 3'-trailer cleavage
KU204_05830	COG2363	Small membrane protein
KU204_05850	COG0513	Belongs to the DEAD box helicase family
KU204_05860	COG0778	Nitroreductase
KU204_05890	COG1286	toxin biosynthetic process
KU204_05915	COG4783	chaperone-mediated protein folding
KU204_05920	COG1610	YqeY-like protein
KU204_06020	COG3111	PFAM Bacterial OB fold (BOF) protein
KU204_06045	COG3243	poly(R)-hydroxyalkanoic acid synthase
KU204_06050	COG0786	glutamate:sodium symporter activity
KU204_06060	COG2186	Transcriptional regulator
KU204_06110	COG0477	Major facilitator Superfamily
KU204_06135	COG2985	domain, Protein
KU204_06145	COG2995	paraquat-inducible protein a
KU204_06150	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KU204_06150	COG3008	intermembrane lipid transfer
KU204_06170	COG0482	sulfurtransferase activity
KU204_06185	COG0488	(ABC) transporter
KU204_06190	COG3173	Aminoglycoside phosphotransferase
KU204_06200	COG2433	Pfam Transposase IS66
KU204_06240	COG1301	dicarboxylic acid transport
KU204_06250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KU204_06255	COG2011	ABC-type metal ion transport system permease component
KU204_06260	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KU204_06265	COG1464	Belongs to the NlpA lipoprotein family
KU204_06270	COG0151	Belongs to the GarS family
KU204_06275	COG0138	bifunctional purine biosynthesis protein purh
KU204_06280	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KU204_06310	COG2308	Evidence 4 Homologs of previously reported genes of
KU204_06320	COG1305	Transglutaminase-like
KU204_06330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KU204_06335	COG0305	Participates in initiation and elongation during chromosome replication
KU204_06360	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KU204_06370	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KU204_06375	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KU204_06400	COG0726	polysaccharide deacetylase
KU204_06400	COG1649	PFAM Uncharacterised BCR, COG1649
KU204_06405	COG1215	transferase activity, transferring glycosyl groups
KU204_06410	COG3658	cytochrome
KU204_06420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KU204_06435	COG0583	DNA-binding transcription factor activity
KU204_06455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU204_06460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KU204_06475	COG1960	acyl-CoA dehydrogenase activity
KU204_06480	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KU204_06485	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU204_06510	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KU204_06515	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KU204_06525	COG2205	protein histidine kinase activity
KU204_06530	COG0745	RESPONSE REGULATOR receiver
KU204_06535	COG0174	glutamine synthetase
KU204_06555	COG0729	surface antigen
KU204_06580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KU204_06585	COG2814	Major facilitator Superfamily
KU204_06630	COG0776	regulation of translation
KU204_06660	COG3409	Peptidoglycan-binding domain 1 protein
KU204_06660	COG3267	Type II secretory pathway component ExeA
KU204_06690	COG0681	Belongs to the peptidase S26 family
KU204_06725	COG4373	Mu-like prophage FluMu protein gp28
KU204_06740	COG4383	Mu-like prophage protein gp29
KU204_06745	COG2369	cell adhesion
KU204_06750	COG5005	Phage virion morphogenesis
KU204_06765	COG4397	Mu-like prophage major head subunit gpT
KU204_06860	COG0583	DNA-binding transcription factor activity
KU204_06875	COG1187	pseudouridine synthase activity
KU204_06895	COG0802	atpase or kinase
KU204_06900	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KU204_06910	COG1923	regulation of RNA biosynthetic process
KU204_06915	COG0697	spore germination
KU204_06930	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KU204_06940	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KU204_06945	COG0519	Catalyzes the synthesis of GMP from XMP
KU204_06945	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KU204_06950	COG4302	ethanolamine ammonia-lyase activity
KU204_06955	COG4303	Ethanolamine ammonia lyase large subunit
KU204_06960	COG0531	amino acid
KU204_06980	COG1454	alcohol dehydrogenase
KU204_06985	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KU204_06995	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
KU204_07015	COG0308	aminopeptidase N
KU204_07055	COG1605	Chorismate mutase
KU204_07070	COG1309	transcriptional regulator
KU204_07080	COG0668	transmembrane transport
KU204_07115	COG4773	Receptor
KU204_07135	COG0488	(ABC) transporter
KU204_07140	COG0589	response to stress
KU204_07165	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KU204_07175	COG3135	benzoate transporter
KU204_07180	COG1522	sequence-specific DNA binding
KU204_07190	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KU204_07195	COG0583	DNA-binding transcription factor activity
KU204_07205	COG0183	Belongs to the thiolase family
KU204_07215	COG2030	dehydratase
KU204_07220	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KU204_07235	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KU204_07245	COG0824	Thioesterase
KU204_07250	COG1454	alcohol dehydrogenase
KU204_07260	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KU204_07280	COG0069	glutamate synthase activity
KU204_07445	COG5410	chromosome segregation
KU204_07570	COG0739	heme binding
KU204_07635	COG2814	Major facilitator Superfamily
KU204_07650	COG0511	ligase activity, forming carbon-carbon bonds
KU204_07670	COG1116	anion transmembrane transporter activity
KU204_07670	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KU204_07675	COG0745	RESPONSE REGULATOR receiver
KU204_07685	COG2146	nitrite reductase [NAD(P)H] activity
KU204_07685	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU204_07690	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU204_07695	COG0243	molybdopterin cofactor binding
KU204_07705	COG0243	molybdopterin cofactor binding
KU204_07710	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KU204_07725	COG0315	cyclic pyranopterin monophosphate synthase activity
KU204_07725	COG0521	Mo-molybdopterin cofactor biosynthetic process
KU204_07730	COG0303	'Molybdopterin
KU204_07740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU204_07745	COG0697	spore germination
KU204_07765	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KU204_07770	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KU204_07825	COG2204	response regulator
KU204_07830	COG3852	Histidine kinase
KU204_07850	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KU204_07855	COG0575	Belongs to the CDS family
KU204_07890	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KU204_07905	COG2137	regulation of response to DNA damage stimulus
KU204_07915	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KU204_07920	COG1011	Hydrolase
KU204_07945	COG1522	sequence-specific DNA binding
KU204_07955	COG1113	amino acid transport
KU204_07970	COG0659	secondary active sulfate transmembrane transporter activity
KU204_07975	COG2135	peptidase activity
KU204_07990	COG5001	Diguanylate cyclase
KU204_07990	COG3300	MHYT domain
KU204_08010	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KU204_08010	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KU204_08010	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KU204_08015	COG1105	Belongs to the carbohydrate kinase PfkB family
KU204_08020	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KU204_08020	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KU204_08050	COG0024	Methionine aminopeptidase
KU204_08055	COG0583	DNA-binding transcription factor activity
KU204_08065	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KU204_08070	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KU204_08075	COG0516	GMP reductase activity
KU204_08075	COG0517	IMP dehydrogenase activity
KU204_08100	COG0552	protein localization to endoplasmic reticulum
KU204_08110	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
KU204_08125	COG4890	Cyd operon protein YbgT
KU204_08130	COG1294	oxidase, subunit
KU204_08155	COG2433	Pfam Transposase IS66
KU204_08160	COG1585	Membrane protein implicated in regulation of membrane protease activity
KU204_08170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KU204_08175	COG4774	siderophore transport
KU204_08190	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KU204_08195	COG0569	domain protein
KU204_08200	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KU204_08230	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KU204_08235	COG0542	response to heat
KU204_08260	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU204_08260	COG1902	pentaerythritol trinitrate reductase activity
KU204_08305	COG2323	membrane
KU204_08310	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KU204_08320	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KU204_08325	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KU204_08330	COG0183	Belongs to the thiolase family
KU204_08335	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KU204_08340	COG0596	Alpha beta hydrolase
KU204_08345	COG2271	Major facilitator Superfamily
KU204_08350	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KU204_08355	COG3485	protocatechuate 3,4-dioxygenase
KU204_08360	COG3485	protocatechuate 3,4-dioxygenase
KU204_08365	COG0710	3-dehydroquinate dehydratase activity
KU204_08370	COG3420	alginic acid biosynthetic process
KU204_08375	COG3659	wide pore channel activity
KU204_08380	COG4993	Dehydrogenase
KU204_08390	COG2391	methyltransferase activity
KU204_08405	COG1414	Transcriptional regulator
KU204_08410	COG0583	DNA-binding transcription factor activity
KU204_08415	COG1960	acyl-CoA dehydrogenase activity
KU204_08440	COG2814	Major facilitator Superfamily
KU204_08450	COG0154	amidase activity
KU204_08470	COG4638	Rieske (2fe-2S)
KU204_08480	COG1028	Short-chain dehydrogenase reductase Sdr
KU204_08490	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU204_08500	COG3733	amine oxidase
KU204_08510	COG1012	belongs to the aldehyde dehydrogenase family
KU204_08520	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KU204_08525	COG0183	Belongs to the thiolase family
KU204_08530	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KU204_08535	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KU204_08545	COG4829	muconolactone delta-isomerase
KU204_08550	COG4948	Mandelate Racemase Muconate Lactonizing
KU204_08555	COG0583	DNA-binding transcription factor activity
KU204_08565	COG2186	Transcriptional regulator
KU204_08585	COG1012	belongs to the aldehyde dehydrogenase family
KU204_08605	COG1960	acyl-CoA dehydrogenase activity
KU204_08610	COG1028	Short-chain dehydrogenase reductase Sdr
KU204_08615	COG3829	transcription factor binding
KU204_08625	COG3162	membrane
KU204_08640	COG1012	belongs to the aldehyde dehydrogenase family
KU204_08655	COG0753	catalase activity
KU204_08675	COG1846	Transcriptional regulator
KU204_08680	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU204_08680	COG1902	pentaerythritol trinitrate reductase activity
KU204_08690	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KU204_08720	COG1309	transcriptional regulator
KU204_08730	COG1335	isochorismatase
KU204_08735	COG0583	DNA-binding transcription factor activity
KU204_08745	COG0475	glutathione-regulated potassium exporter activity
KU204_08745	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KU204_08755	COG1473	amidohydrolase
KU204_08765	COG2831	hemolysin activation secretion protein
KU204_08770	COG3210	domain, Protein
KU204_08800	COG2188	Transcriptional regulator
KU204_08815	COG0583	DNA-binding transcription factor activity
KU204_08845	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KU204_08865	COG1566	PFAM secretion protein HlyD family protein
KU204_08880	COG1012	belongs to the aldehyde dehydrogenase family
KU204_08885	COG0129	dihydroxy-acid dehydratase activity
KU204_08895	COG0583	DNA-binding transcription factor activity
KU204_08900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KU204_08910	COG2084	Dehydrogenase
KU204_08915	COG2207	Transcriptional regulator
KU204_08930	COG1064	alcohol dehydrogenase
KU204_08940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KU204_08945	COG1120	ATPase activity
KU204_08965	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KU204_09080	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KU204_09130	COG1028	Short-chain dehydrogenase reductase Sdr
KU204_09145	COG2207	Transcriptional regulator
KU204_09155	COG2205	protein histidine kinase activity
KU204_09160	COG0745	RESPONSE REGULATOR receiver
KU204_09165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU204_09170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KU204_09185	COG2072	flavoprotein involved in K transport
KU204_09205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KU204_09225	COG3539	Fimbrial protein
KU204_09255	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KU204_09265	COG0753	catalase activity
KU204_09280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KU204_09340	COG3433	isochorismatase activity
KU204_09340	COG1535	isochorismatase
KU204_09345	COG1028	Short-chain dehydrogenase reductase Sdr
KU204_09350	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KU204_09355	COG4149	molybdate abc transporter
KU204_09360	COG0725	ABC transporter, periplasmic molybdate-binding protein
KU204_09370	COG4638	Rieske (2fe-2S)
KU204_09375	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KU204_09380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU204_09380	COG0543	2 iron, 2 sulfur cluster binding
KU204_09405	COG1028	Short-chain dehydrogenase reductase Sdr
KU204_09420	COG2207	Transcriptional regulator
KU204_09430	COG1028	Short-chain dehydrogenase reductase Sdr
KU204_09435	COG2610	gluconate transmembrane transporter activity
KU204_09445	COG0583	DNA-binding transcription factor activity
KU204_09455	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KU204_09460	COG2031	fatty acid transporter
KU204_09465	COG0183	Belongs to the thiolase family
KU204_09470	COG0583	DNA-binding transcription factor activity
KU204_09475	COG0583	DNA-binding transcription factor activity
KU204_09490	COG1027	Aspartate ammonia-lyase
KU204_09500	COG0477	Major facilitator Superfamily
KU204_09520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU204_09525	COG4521	taurine ABC transporter
KU204_09540	COG2188	Transcriptional regulator
KU204_09550	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KU204_09555	COG1733	regulation of RNA biosynthetic process
KU204_09560	COG2207	Transcriptional regulator
KU204_09560	COG3708	Transcriptional regulator
KU204_09575	COG0730	response to heat
KU204_09585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KU204_09585	COG3453	Protein conserved in bacteria
KU204_09595	COG3781	membrane
KU204_09600	COG1063	alcohol dehydrogenase
KU204_09610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KU204_09615	COG0508	dehydrogenase complex catalyzes the overall conversion of
KU204_09620	COG0022	dehydrogenase e1 component
KU204_09625	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KU204_09630	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KU204_09645	COG3706	GGDEF domain
KU204_09660	COG0133	tryptophan synthase activity
KU204_09670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KU204_09705	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KU204_09730	COG2226	methyltransferase
KU204_09785	COG0842	Transport permease protein
KU204_09790	COG0842	Transport permease protein
KU204_09795	COG1131	(ABC) transporter
KU204_09810	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KU204_09815	COG4773	Receptor
KU204_09835	COG0730	response to heat
KU204_09840	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KU204_09860	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KU204_09875	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KU204_09915	COG4264	IucA IucC family
KU204_09920	COG4264	IucA IucC family
KU204_09940	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KU204_09955	COG1960	acyl-CoA dehydrogenase activity
KU204_09960	COG1960	acyl-CoA dehydrogenase activity
KU204_09965	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KU204_09970	COG2207	Transcriptional regulator
KU204_09975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KU204_09980	COG0776	regulation of translation
KU204_10005	COG0822	iron-sulfur transferase activity
KU204_10010	COG0316	Belongs to the HesB IscA family
KU204_10040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KU204_10060	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KU204_10065	COG0702	epimerase
KU204_10100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KU204_10110	COG0339	signal peptide processing
KU204_10160	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KU204_10165	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KU204_10195	COG0776	regulation of translation
KU204_10260	COG0084	hydrolase, TatD family'
KU204_10280	COG1663	tetraacyldisaccharide 4'-kinase activity
KU204_10285	COG1132	(ABC) transporter
KU204_10295	COG0811	peptide transport
KU204_10300	COG1475	DNA binding
KU204_10305	COG1192	Involved in chromosome partitioning
KU204_10315	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KU204_10330	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KU204_10335	COG0191	fructose-bisphosphate aldolase activity
KU204_10355	COG0424	maF-like protein
KU204_10360	COG2850	peptidyl-arginine hydroxylation
KU204_10370	COG0640	Transcriptional regulator
KU204_10385	COG3619	membrane
KU204_10390	COG3122	Protein conserved in bacteria
KU204_10395	COG1132	(ABC) transporter
KU204_10415	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KU204_10420	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KU204_10430	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KU204_10430	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KU204_10430	COG0506	proline dehydrogenase activity
KU204_10435	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KU204_10450	COG3698	Phosphodiester glycosidase
KU204_10460	COG2353	YceI-like domain
KU204_10470	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KU204_10515	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KU204_10515	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KU204_10540	COG3539	Fimbrial protein
KU204_10545	COG3121	Chaperone
KU204_10570	COG0697	spore germination
KU204_10580	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KU204_10590	COG0583	DNA-binding transcription factor activity
KU204_10610	COG1309	transcriptional regulator
KU204_10625	COG1522	sequence-specific DNA binding
KU204_10635	COG1126	abc transporter atp-binding protein
KU204_10640	COG0765	amino acid transport
KU204_10645	COG0765	amino acid transport
KU204_10675	COG1464	Belongs to the NlpA lipoprotein family
KU204_10685	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KU204_10690	COG2011	ABC-type metal ion transport system permease component
KU204_10695	COG0012	GTP binding
KU204_10720	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KU204_10760	COG0386	Belongs to the glutathione peroxidase family
KU204_10770	COG0436	Aminotransferase
KU204_10810	COG3634	alkyl hydroperoxide reductase activity
KU204_10825	COG0583	DNA-binding transcription factor activity
KU204_10830	COG0798	PFAM Bile acid sodium symporter
KU204_10835	COG0640	Transcriptional regulator
KU204_10850	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KU204_10860	COG0583	DNA-binding transcription factor activity
KU204_10870	COG1953	Uracil, thiamine, allantoin
KU204_10880	COG2175	clavaminate synthase activity
KU204_10885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU204_10890	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KU204_10895	COG4521	taurine ABC transporter
KU204_10905	COG0477	Major facilitator Superfamily
KU204_10925	COG1271	oxidase subunit
KU204_10930	COG1294	oxidase, subunit
KU204_10940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU204_10960	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KU204_10980	COG3052	prosthetic group binding
KU204_10985	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
KU204_10995	COG2814	Major facilitator Superfamily
KU204_11015	COG1346	cytolysis
KU204_11025	COG0583	DNA-binding transcription factor activity
KU204_11030	COG0625	glutathione transferase activity
KU204_11035	COG0625	glutathione transferase activity
KU204_11040	COG0583	DNA-binding transcription factor activity
KU204_11055	COG1045	serine acetyltransferase
KU204_11060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KU204_11065	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KU204_11075	COG1280	lysine exporter protein (LysE YggA)
KU204_11090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KU204_11095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KU204_11100	COG1126	abc transporter atp-binding protein
KU204_11105	COG0765	amino acid transport
KU204_11110	COG0765	amino acid transport
KU204_11130	COG0784	Response regulator, receiver
KU204_11130	COG2205	protein histidine kinase activity
KU204_11150	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KU204_11170	COG1028	Short-chain dehydrogenase reductase Sdr
KU204_11220	COG0583	DNA-binding transcription factor activity
KU204_11240	COG0318	PFAM AMP-dependent synthetase and ligase
KU204_11245	COG1309	transcriptional regulator
KU204_11250	COG1960	acyl-CoA dehydrogenase activity
KU204_11255	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KU204_11260	COG1024	Enoyl-CoA hydratase
KU204_11265	COG4770	biotin carboxylase activity
KU204_11275	COG0583	DNA-binding transcription factor activity
KU204_11290	COG1960	acyl-CoA dehydrogenase activity
KU204_11300	COG2814	Major facilitator Superfamily
KU204_11310	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KU204_11315	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KU204_11320	COG2814	Major facilitator Superfamily
KU204_11325	COG1960	acyl-CoA dehydrogenase activity
KU204_11330	COG1024	Enoyl-CoA hydratase
KU204_11335	COG1028	Short-chain dehydrogenase reductase Sdr
KU204_11340	COG1250	3-hydroxyacyl-CoA dehydrogenase
KU204_11345	COG0183	Belongs to the thiolase family
KU204_11355	COG2814	Major facilitator Superfamily
KU204_11365	COG1024	Enoyl-CoA hydratase
KU204_11380	COG1960	acyl-CoA dehydrogenase activity
KU204_11385	COG2814	Major facilitator Superfamily
KU204_11390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KU204_11395	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KU204_11410	COG3842	ATPase activity
KU204_11415	COG1840	ABC-type Fe3 transport system, periplasmic component
KU204_11425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU204_11430	COG1414	Transcriptional regulator
KU204_11440	COG0583	DNA-binding transcription factor activity
KU204_11445	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KU204_11450	COG1012	belongs to the aldehyde dehydrogenase family
KU204_11460	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KU204_11470	COG1012	belongs to the aldehyde dehydrogenase family
KU204_11475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KU204_11480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU204_11485	COG2267	carboxylic ester hydrolase activity
KU204_11505	COG3038	cytochrome b561
KU204_11510	COG0753	catalase activity
KU204_11545	COG2050	protein possibly involved in aromatic compounds catabolism
KU204_11555	COG3327	negative regulation of DNA-templated transcription, initiation
KU204_11560	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
KU204_11565	COG0183	Belongs to the thiolase family
KU204_11570	COG1250	3-hydroxyacyl-CoA dehydrogenase
KU204_11575	COG1024	Enoyl-CoA hydratase
KU204_11580	COG1024	Enoyl-CoA hydratase
KU204_11585	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU204_11590	COG2151	metal-sulfur cluster biosynthetic enzyme
KU204_11595	COG3396	Phenylacetate-CoA oxygenase
KU204_11600	COG3460	Phenylacetate-CoA oxygenase
KU204_11605	COG3396	Phenylacetate-CoA oxygenase
KU204_11610	COG1012	belongs to the aldehyde dehydrogenase family
KU204_11610	COG2030	dehydratase
KU204_11615	COG1760	l-serine dehydratase
KU204_11620	COG0531	amino acid
KU204_11625	COG1012	belongs to the aldehyde dehydrogenase family
KU204_11640	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU204_11650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KU204_11670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU204_11680	COG0789	Transcriptional regulator
KU204_11695	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KU204_11710	COG2807	transmembrane transport
KU204_11715	COG0590	tRNA wobble adenosine to inosine editing
KU204_11830	COG1116	anion transmembrane transporter activity
KU204_11835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KU204_11845	COG0864	Transcriptional regulator
KU204_11865	COG2249	NAD(P)H dehydrogenase (quinone) activity
KU204_11870	COG0439	Biotin carboxylase
KU204_11895	COG1309	transcriptional regulator
KU204_11915	COG0038	chloride channel
KU204_11920	COG4770	biotin carboxylase activity
KU204_11940	COG1914	H( )-stimulated, divalent metal cation uptake system
KU204_11945	COG0583	DNA-binding transcription factor activity
KU204_11995	COG1250	3-hydroxyacyl-CoA dehydrogenase
KU204_12015	COG2814	Major facilitator Superfamily
KU204_12025	COG1560	Kdo2-lipid A biosynthetic process
KU204_12035	COG5006	permease, DMT superfamily
KU204_12040	COG1522	sequence-specific DNA binding
KU204_12055	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KU204_12065	COG4122	O-methyltransferase activity
KU204_12095	COG1538	Outer membrane efflux protein
KU204_12100	COG1137	ATPase activity
KU204_12105	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KU204_12115	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KU204_12120	COG0517	IMP dehydrogenase activity
KU204_12120	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KU204_12155	COG2814	Major facilitator Superfamily
KU204_12190	COG1278	Cold shock
KU204_12195	COG1280	lysine exporter protein (LysE YggA)
KU204_12225	COG1570	exodeoxyribonuclease VII activity
KU204_12275	COG0583	DNA-binding transcription factor activity
KU204_12280	COG4638	Rieske (2fe-2S)
KU204_12285	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KU204_12290	COG0543	2 iron, 2 sulfur cluster binding
KU204_12290	COG0633	Ferredoxin
KU204_12295	COG1028	Short-chain dehydrogenase reductase Sdr
KU204_12300	COG3135	benzoate transporter
KU204_12305	COG2814	Major facilitator Superfamily
KU204_12320	COG1643	Atp-dependent helicase
KU204_12325	COG0450	alkyl hydroperoxide reductase
KU204_12335	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KU204_12345	COG3634	alkyl hydroperoxide reductase activity
KU204_12365	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KU204_12370	COG0625	glutathione transferase activity
KU204_12380	COG2885	chlorophyll binding
KU204_12415	COG0542	response to heat
KU204_12430	COG1765	OsmC-like protein
KU204_12450	COG0667	Aldo Keto reductase
KU204_12465	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KU204_12475	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KU204_12485	COG0527	aspartate kinase activity
KU204_12495	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KU204_12505	COG3038	cytochrome b561
KU204_12510	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KU204_12535	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KU204_12575	COG1902	pentaerythritol trinitrate reductase activity
KU204_12575	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU204_12585	COG3706	GGDEF domain
KU204_12585	COG5001	Diguanylate cyclase
KU204_12585	COG4251	negative regulation of phosphorylation
KU204_12585	COG2203	Gaf domain
KU204_12595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KU204_12615	COG4172	Belongs to the ABC transporter superfamily
KU204_12620	COG4239	(ABC) transporter, permease
KU204_12625	COG4174	ABC transporter (Permease)
KU204_12635	COG0741	lytic transglycosylase activity
KU204_12635	COG1388	LysM domain
KU204_12635	COG0741	lytic transglycosylase activity
KU204_12635	COG1388	LysM domain
KU204_12640	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KU204_12680	COG0583	DNA-binding transcription factor activity
KU204_12685	COG1279	arginine transmembrane transporter activity
KU204_12705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU204_12710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU204_12715	COG0006	proline dipeptidase activity
KU204_12755	COG2194	sulfuric ester hydrolase activity
KU204_12800	COG0739	heme binding
KU204_13130	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KU204_13155	COG3384	dioxygenase
KU204_13165	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KU204_13170	COG2878	Part of a membrane complex involved in electron transport
KU204_13175	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KU204_13200	COG0768	penicillin binding
KU204_13205	COG0742	ribosomal rna small subunit methyltransferase
KU204_13220	COG0830	nickel cation binding
KU204_13265	COG1253	flavin adenine dinucleotide binding
KU204_13270	COG2851	Citrate transporter
KU204_13325	COG1773	rubredoxin
KU204_13330	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU204_13340	COG0583	DNA-binding transcription factor activity
KU204_13365	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KU204_13370	COG4181	ATPase activity
KU204_13415	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KU204_13435	COG0306	phosphate transporter
KU204_13445	COG3958	Transketolase
KU204_13450	COG3959	Transketolase, thiamine diphosphate binding domain
KU204_13455	COG2271	Major facilitator Superfamily
KU204_13460	COG1028	Short-chain dehydrogenase reductase Sdr
KU204_13465	COG0583	DNA-binding transcription factor activity
KU204_13480	COG2223	nitrite transmembrane transporter activity
KU204_13485	COG2207	Transcriptional regulator
KU204_13490	COG2066	Belongs to the glutaminase family
KU204_13495	COG0242	peptide deformylase activity
KU204_13500	COG0477	Major facilitator Superfamily
KU204_13510	COG0028	Belongs to the TPP enzyme family
KU204_13525	COG1028	Short-chain dehydrogenase reductase Sdr
KU204_13530	COG2267	carboxylic ester hydrolase activity
KU204_13540	COG2271	Major facilitator Superfamily
KU204_13545	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU204_13555	COG1028	Short-chain dehydrogenase reductase Sdr
KU204_13575	COG1414	Transcriptional regulator
KU204_13590	COG1024	Enoyl-CoA hydratase
KU204_13600	COG1215	transferase activity, transferring glycosyl groups
KU204_13605	COG1649	PFAM Uncharacterised BCR, COG1649
KU204_13605	COG0726	polysaccharide deacetylase
KU204_13615	COG4681	YaeQ
KU204_13625	COG0523	cobalamin synthesis protein
KU204_13635	COG1607	acyl-coa hydrolase
KU204_13645	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU204_13650	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU204_13655	COG1309	transcriptional regulator
KU204_13680	COG2040	homocysteine
KU204_13685	COG0531	amino acid
KU204_13740	COG1595	DNA-templated transcription, initiation
KU204_13750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU204_13755	COG0477	Major facilitator Superfamily
KU204_13775	COG0084	hydrolase, TatD family'
KU204_13810	COG0629	single-stranded DNA binding
KU204_13865	COG0582	viral genome integration into host DNA
KU204_13970	COG0592	DNA-directed DNA polymerase activity
KU204_14010	COG2026	Addiction module toxin, RelE StbE family
KU204_14205	COG1484	DNA-dependent DNA replication
KU204_14295	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KU204_14365	COG0405	Gamma-glutamyltransferase
KU204_14370	COG2814	Major facilitator Superfamily
KU204_14380	COG2050	protein possibly involved in aromatic compounds catabolism
KU204_14395	COG1090	epimerase
KU204_14415	COG0420	3'-5' exonuclease activity
KU204_14440	COG0735	belongs to the Fur family
KU204_14445	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KU204_14465	COG0121	glutamine amidotransferase
KU204_14480	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KU204_14490	COG0210	DNA helicase
KU204_14495	COG2885	chlorophyll binding
KU204_14500	COG0204	Acyl-transferase
KU204_14515	COG2894	cell division
KU204_14540	COG1280	lysine exporter protein (LysE YggA)
KU204_14545	COG1674	ftsk spoiiie
KU204_14545	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KU204_14550	COG0492	ferredoxin-NADP+ reductase activity
KU204_14555	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KU204_14565	COG0456	acetyltransferase
KU204_14610	COG1981	membrane
KU204_14625	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KU204_14625	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KU204_14645	COG1012	belongs to the aldehyde dehydrogenase family
KU204_14655	COG0657	acetylesterase activity
KU204_14665	COG0473	3-isopropylmalate dehydrogenase activity
KU204_14670	COG0583	DNA-binding transcription factor activity
KU204_14690	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KU204_14715	COG0564	pseudouridine synthase activity
KU204_14725	COG0358	DNA primase activity
KU204_14740	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KU204_14770	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KU204_14800	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KU204_14810	COG0352	thiamine-phosphate diphosphorylase activity
KU204_14810	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KU204_14810	COG0351	phosphomethylpyrimidine kinase
KU204_14815	COG1652	LysM domain
KU204_14840	COG1399	metal-binding, possibly nucleic acid-binding protein
KU204_14845	COG3101	peptidyl-lysine hydroxylation
KU204_14850	COG0009	L-threonylcarbamoyladenylate synthase
KU204_14855	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KU204_14860	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KU204_14875	COG4106	trans-aconitate 2-methyltransferase activity
KU204_14890	COG0596	Alpha beta hydrolase
KU204_14890	COG2226	methyltransferase
KU204_14890	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KU204_14895	COG1877	trehalose-phosphatase activity
KU204_14900	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
KU204_14905	COG2223	nitrite transmembrane transporter activity
KU204_14925	COG1196	nuclear chromosome segregation
KU204_14935	COG0730	response to heat
KU204_14950	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KU204_14960	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KU204_15010	COG0489	protein tyrosine kinase activity
KU204_15020	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KU204_15020	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KU204_15050	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KU204_15055	COG2081	HI0933 family
KU204_15065	COG0668	transmembrane transport
KU204_15085	COG0583	DNA-binding transcription factor activity
KU204_15105	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KU204_15110	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KU204_15140	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KU204_15180	COG0745	RESPONSE REGULATOR receiver
KU204_15200	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KU204_15210	COG2205	protein histidine kinase activity
KU204_15280	COG4993	Dehydrogenase
KU204_15305	COG0384	phenazine biosynthesis protein PhzF
KU204_15325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU204_15340	COG0583	DNA-binding transcription factor activity
KU204_15370	COG0583	DNA-binding transcription factor activity
KU204_15385	COG0583	DNA-binding transcription factor activity
KU204_15390	COG1053	succinate dehydrogenase
KU204_15400	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KU204_15405	COG2814	Major facilitator Superfamily
KU204_15410	COG1960	acyl-CoA dehydrogenase activity
KU204_15415	COG0583	DNA-binding transcription factor activity
KU204_15420	COG1063	alcohol dehydrogenase
KU204_15450	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KU204_15455	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KU204_15460	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KU204_15475	COG3667	copper resistance
KU204_15480	COG2132	Multicopper oxidase
KU204_15490	COG0561	phosphatase activity
KU204_15495	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KU204_15520	COG1214	PFAM Peptidase M22, glycoprotease
KU204_15575	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KU204_15585	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KU204_15590	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KU204_15595	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KU204_15655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KU204_15665	COG1846	Transcriptional regulator
KU204_15670	COG1764	response to oxidative stress
KU204_15720	COG0037	tRNA processing
KU204_15730	COG0248	Ppx GppA phosphatase
KU204_15760	COG0072	phenylalanine-tRNA ligase activity
KU204_15800	COG1238	metal cluster binding
KU204_15805	COG0625	glutathione transferase activity
KU204_15820	COG0318	PFAM AMP-dependent synthetase and ligase
KU204_15825	COG3028	Belongs to the UPF0307 family
KU204_15830	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KU204_15850	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KU204_15855	COG0617	tRNA 3'-terminal CCA addition
KU204_15860	COG1555	photosystem II stabilization
KU204_15865	COG3956	TIGRFAM MazG family protein
KU204_15875	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KU204_15895	COG0784	Response regulator, receiver
KU204_15895	COG2205	protein histidine kinase activity
KU204_15895	COG5002	protein histidine kinase activity
KU204_15900	COG1024	Enoyl-CoA hydratase
KU204_15905	COG2084	Dehydrogenase
KU204_15910	COG3622	Belongs to the hyi family
KU204_15940	COG0697	spore germination
KU204_15950	COG2814	Major facilitator Superfamily
KU204_15955	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KU204_15965	COG0583	DNA-binding transcription factor activity
KU204_15975	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KU204_15990	COG0084	hydrolase, TatD family'
KU204_16005	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KU204_16035	COG0440	acetolactate synthase activity
KU204_16040	COG0028	Belongs to the TPP enzyme family
KU204_16065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU204_16070	COG1136	(ABC) transporter
KU204_16070	COG0577	efflux transmembrane transporter activity
KU204_16075	COG1538	Outer membrane efflux protein
KU204_16090	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KU204_16095	COG1162	GTPase activity
KU204_16105	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KU204_16125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KU204_16130	COG1028	Short-chain dehydrogenase reductase Sdr
KU204_16170	COG2986	histidine ammonia-lyase
KU204_16185	COG0318	PFAM AMP-dependent synthetase and ligase
KU204_16195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KU204_16240	COG1426	Protein conserved in bacteria
KU204_16275	COG0793	Belongs to the peptidase S41A family
KU204_16290	COG2267	carboxylic ester hydrolase activity
KU204_16300	COG1012	belongs to the aldehyde dehydrogenase family
KU204_16305	COG3265	gluconokinase activity
KU204_16315	COG0800	Aldolase
KU204_16330	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KU204_16335	COG0280	phosphate acetyltransferase
KU204_16335	COG0857	belongs to the CobB CobQ family
KU204_16340	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KU204_16340	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KU204_16360	COG0740	serine-type endopeptidase activity
KU204_16370	COG4774	siderophore transport
KU204_16380	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KU204_16390	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KU204_16390	COG2813	Specifically methylates the guanine in position
KU204_16490	COG0788	formyltetrahydrofolate deformylase activity
KU204_16515	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KU204_16515	COG4651	solute:proton antiporter activity
KU204_16535	COG0724	RNA recognition motif
KU204_16540	COG0210	DNA helicase
KU204_16565	COG1733	regulation of RNA biosynthetic process
KU204_16575	COG2900	Belongs to the SlyX family
KU204_16580	COG0488	(ABC) transporter
KU204_16585	COG1280	lysine exporter protein (LysE YggA)
KU204_16590	COG1560	Kdo2-lipid A biosynthetic process
KU204_16600	COG1301	dicarboxylic acid transport
KU204_16655	COG0473	3-isopropylmalate dehydrogenase activity
KU204_16720	COG0583	DNA-binding transcription factor activity
KU204_16730	COG0625	glutathione transferase activity
KU204_16735	COG2378	regulation of single-species biofilm formation
KU204_16740	COG0546	phosphoglycolate phosphatase activity
KU204_16750	COG1530	ribonuclease E activity
KU204_16755	COG0318	PFAM AMP-dependent synthetase and ligase
KU204_16770	COG0583	DNA-binding transcription factor activity
KU204_16775	COG4221	oxidoreductase activity
KU204_16780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KU204_16790	COG0534	Mate efflux family protein
KU204_16805	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KU204_16845	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KU204_16850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KU204_16865	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KU204_16875	COG0644	oxidoreductase
KU204_16875	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
KU204_16880	COG0425	Belongs to the sulfur carrier protein TusA family
KU204_16885	COG4535	Mg2 and Co2 transporter CorC
KU204_16895	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KU204_16915	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KU204_16920	COG0475	glutathione-regulated potassium exporter activity
KU204_16920	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KU204_16925	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KU204_16935	COG0484	heat shock protein binding
KU204_16940	COG0789	Transcriptional regulator
KU204_16945	COG0598	Magnesium transport protein CorA
KU204_16960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KU204_16965	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KU204_16970	COG1074	ATP-dependent DNA helicase activity
KU204_16975	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KU204_16995	COG2226	methyltransferase
KU204_17010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU204_17015	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KU204_17030	COG2111	Na H antiporter
KU204_17030	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KU204_17035	COG1006	Multisubunit Na H antiporter MnhC subunit
KU204_17040	COG0651	ATP synthesis coupled electron transport
KU204_17045	COG1863	multisubunit Na H antiporter MnhE subunit
KU204_17050	COG2212	antiporter activity
KU204_17055	COG1320	monovalent cation:proton antiporter activity
KU204_17070	COG0195	Participates in both transcription termination and antitermination
KU204_17120	COG0237	dephospho-CoA kinase activity
KU204_17130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KU204_17145	COG0497	DNA recombination
KU204_17155	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KU204_17185	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KU204_17185	COG2169	Transcriptional regulator
KU204_17190	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KU204_17255	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KU204_17270	COG0326	Molecular chaperone. Has ATPase activity
KU204_17285	COG2056	Na+-H+ antiporter family
KU204_17290	COG0596	Alpha beta hydrolase
KU204_17385	COG0546	phosphoglycolate phosphatase activity
KU204_17390	COG1716	ATPase activity
KU204_17435	COG0181	hydroxymethylbilane synthase activity
KU204_17445	COG3275	phosphorelay sensor kinase activity
KU204_17465	COG1538	Outer membrane efflux protein
KU204_17470	COG0697	spore germination
KU204_17495	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KU204_17500	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KU204_17505	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KU204_17510	COG0772	Belongs to the SEDS family
KU204_17535	COG4974	Belongs to the 'phage' integrase family
KU204_17540	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KU204_17550	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KU204_17560	COG2197	response regulator
KU204_17575	COG0793	Belongs to the peptidase S41A family
KU204_17580	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KU204_17585	COG0795	lipopolysaccharide-transporting ATPase activity
KU204_17625	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KU204_17625	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KU204_17635	COG0004	ammonium transporteR
KU204_17640	COG0347	Belongs to the P(II) protein family
KU204_17650	COG0606	chelatase, subunit chli
KU204_17730	COG0659	secondary active sulfate transmembrane transporter activity
KU204_17735	COG0589	response to stress
KU204_17775	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KU204_17820	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KU204_17880	COG0659	secondary active sulfate transmembrane transporter activity
KU204_17885	COG0589	response to stress
KU204_17915	COG0606	chelatase, subunit chli
KU204_17920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU204_17930	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU204_17945	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KU204_17960	COG0318	PFAM AMP-dependent synthetase and ligase
KU204_17970	COG0477	Major facilitator Superfamily
KU204_17975	COG2860	membrane
KU204_17985	COG1253	flavin adenine dinucleotide binding
KU204_18005	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KU204_18040	COG0655	NAD(P)H dehydrogenase (quinone) activity
KU204_18050	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KU204_18085	COG1309	transcriptional regulator
KU204_18120	COG0758	DNA mediated transformation
KU204_18130	COG0697	spore germination
KU204_18135	COG1309	transcriptional regulator
KU204_18150	COG0386	Belongs to the glutathione peroxidase family
KU204_18215	COG1121	(ABC) transporter
KU204_18220	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KU204_18225	COG1280	lysine exporter protein (LysE YggA)
KU204_18230	COG2837	iron assimilation
KU204_18240	COG0281	malic enzyme
KU204_18285	COG0519	Catalyzes the synthesis of GMP from XMP
KU204_18285	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KU204_18290	COG4399	Belongs to the UPF0754 family
KU204_18295	COG2259	Doxx family
KU204_18300	COG0586	Pfam SNARE associated Golgi protein
KU204_18315	COG1192	Involved in chromosome partitioning
KU204_18325	COG0271	Belongs to the BolA IbaG family
KU204_18345	COG2267	carboxylic ester hydrolase activity
KU204_18365	COG3321	synthase
KU204_18365	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KU204_18365	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KU204_18365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KU204_18370	COG1960	acyl-CoA dehydrogenase activity
KU204_18380	COG2197	response regulator
KU204_18390	COG3916	Acyl-homoserine-lactone synthase
KU204_18395	COG0477	Major facilitator Superfamily
KU204_18400	COG1024	Enoyl-CoA hydratase
KU204_18405	COG1024	Enoyl-CoA hydratase
KU204_18410	COG1960	acyl-CoA dehydrogenase activity
KU204_18415	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KU204_18435	COG1113	amino acid transport
KU204_18440	COG1113	amino acid transport
KU204_18445	COG0251	oxidation-reduction process
KU204_18485	COG0564	pseudouridine synthase activity
KU204_18545	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KU204_18560	COG1802	Transcriptional regulator
KU204_18570	COG1448	Aminotransferase
KU204_18575	COG0277	FAD linked oxidase domain protein
KU204_18585	COG2186	Transcriptional regulator
KU204_18595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KU204_18600	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KU204_18615	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KU204_18620	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KU204_18635	COG1215	transferase activity, transferring glycosyl groups
KU204_18680	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KU204_18710	COG0728	peptidoglycan biosynthetic process
KU204_18715	COG3023	N-Acetylmuramoyl-L-alanine amidase
KU204_18770	COG0546	phosphoglycolate phosphatase activity
KU204_18775	COG1028	Short-chain dehydrogenase reductase Sdr
KU204_18795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KU204_18800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KU204_18805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KU204_18810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU204_18815	COG1116	anion transmembrane transporter activity
KU204_18820	COG1309	transcriptional regulator
KU204_18825	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KU204_18835	COG0196	riboflavin kinase activity
KU204_18840	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KU204_18850	COG1047	Peptidyl-prolyl cis-trans
KU204_18890	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KU204_18895	COG0657	acetylesterase activity
KU204_18945	COG2951	lytic endotransglycosylase activity
KU204_18950	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KU204_18965	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KU204_18975	COG0671	phosphoesterase, PA-phosphatase related
KU204_18980	COG0861	Integral membrane protein TerC family
KU204_18990	COG0754	glutathionylspermidine amidase activity
KU204_19000	COG0402	S-adenosylhomocysteine deaminase activity
KU204_19015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KU204_19020	COG1230	cation diffusion facilitator family transporter
KU204_19035	COG0706	membrane insertase activity
KU204_19105	COG1525	nuclease
KU204_19175	COG1475	DNA binding
KU204_19190	COG3853	Toxic anion resistance protein (TelA)
KU204_19290	COG0484	heat shock protein binding
KU204_19380	COG0741	lytic transglycosylase activity
KU204_19415	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process