locus-tag	class	description
KU058_00010	COG0592	DNA-directed DNA polymerase activity
KU058_00020	COG0187	DNA topoisomerase II activity
KU058_00030	COG0586	Pfam SNARE associated Golgi protein
KU058_00035	COG0488	(ABC) transporter
KU058_00060	COG0596	Alpha beta hydrolase
KU058_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KU058_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KU058_00110	COG0733	neurotransmitter:sodium symporter activity
KU058_00150	COG2233	PERMEase
KU058_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU058_00200	COG2814	Major facilitator Superfamily
KU058_00205	COG0656	L-ascorbic acid biosynthetic process
KU058_00210	COG0583	DNA-binding transcription factor activity
KU058_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU058_00230	COG1064	alcohol dehydrogenase
KU058_00235	COG2818	Glycosylase
KU058_00250	COG1194	a g-specific adenine glycosylase
KU058_00270	COG2983	Belongs to the UPF0260 family
KU058_00275	COG2133	pyrroloquinoline quinone binding
KU058_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KU058_00285	COG2116	formate transmembrane transporter activity
KU058_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU058_00310	COG1335	isochorismatase
KU058_00315	COG0385	Bile acid
KU058_00320	COG0534	Mate efflux family protein
KU058_00325	COG1683	Conserved Protein
KU058_00345	COG0625	glutathione transferase activity
KU058_00355	COG1113	amino acid transport
KU058_00365	COG0523	cobalamin synthesis protein
KU058_00375	COG2188	Transcriptional regulator
KU058_00405	COG0010	Belongs to the arginase family
KU058_00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KU058_00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KU058_00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KU058_00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KU058_00540	COG0534	Mate efflux family protein
KU058_00545	COG0436	Aminotransferase
KU058_00550	COG2733	membrane
KU058_00565	COG2918	glutathione biosynthetic process
KU058_00580	COG1388	LysM domain
KU058_00580	COG0791	NLP P60 protein
KU058_00595	COG3150	esterase
KU058_00605	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_00610	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
KU058_00620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU058_00630	COG2233	PERMEase
KU058_00635	COG2351	hydroxyisourate hydrolase activity
KU058_00670	COG3706	GGDEF domain
KU058_00685	COG1393	Belongs to the ArsC family
KU058_00690	COG0708	Exodeoxyribonuclease III
KU058_00710	COG0189	ligase activity
KU058_00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KU058_00740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KU058_00755	COG4942	peptidase
KU058_00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
KU058_00775	COG2119	membrane
KU058_00780	COG4774	siderophore transport
KU058_00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU058_00785	COG0426	domain, Protein
KU058_00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KU058_00830	COG1902	pentaerythritol trinitrate reductase activity
KU058_00835	COG1519	Transferase
KU058_00840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KU058_00845	COG0668	transmembrane transport
KU058_00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KU058_00860	COG1335	isochorismatase
KU058_00865	COG1522	sequence-specific DNA binding
KU058_00870	COG3328	transposase activity
KU058_00895	COG0784	Response regulator, receiver
KU058_00895	COG2198	Histidine kinase
KU058_00895	COG2205	protein histidine kinase activity
KU058_00900	COG3162	membrane
KU058_00905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KU058_00915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU058_00935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KU058_00940	COG1309	transcriptional regulator
KU058_00960	COG0351	phosphomethylpyrimidine kinase
KU058_00960	COG0352	thiamine-phosphate diphosphorylase activity
KU058_00960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KU058_00970	COG2814	Major facilitator Superfamily
KU058_00985	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KU058_00995	COG1113	amino acid transport
KU058_01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KU058_01010	COG1012	belongs to the aldehyde dehydrogenase family
KU058_01020	COG1335	isochorismatase
KU058_01050	COG2814	Major facilitator Superfamily
KU058_01055	COG0583	DNA-binding transcription factor activity
KU058_01075	COG0667	Aldo Keto reductase
KU058_01110	COG1733	regulation of RNA biosynthetic process
KU058_01115	COG2249	NAD(P)H dehydrogenase (quinone) activity
KU058_01180	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KU058_01195	COG2329	Antibiotic biosynthesis monooxygenase
KU058_01225	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KU058_01255	COG0427	acetyl-CoA hydrolase
KU058_01280	COG0659	secondary active sulfate transmembrane transporter activity
KU058_01285	COG4221	oxidoreductase activity
KU058_01290	COG2873	o-acetylhomoserine
KU058_01295	COG0488	(ABC) transporter
KU058_01380	COG0833	amino acid
KU058_01425	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KU058_01430	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KU058_01445	COG2226	methyltransferase
KU058_01495	COG0067	glutamate synthase
KU058_01495	COG0069	glutamate synthase activity
KU058_01495	COG0070	glutamate synthase
KU058_01500	COG0493	'glutamate synthase
KU058_01510	COG1704	LemA family
KU058_01515	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KU058_01535	COG3307	-O-antigen
KU058_01560	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KU058_01575	COG0194	GDP metabolic process
KU058_01625	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KU058_01645	COG5380	lipid catabolic process
KU058_01650	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KU058_01675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KU058_01680	COG0277	FAD linked oxidase domain protein
KU058_01690	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KU058_01695	COG2249	NAD(P)H dehydrogenase (quinone) activity
KU058_01710	COG1289	transmembrane transporter activity
KU058_01720	COG0628	permease
KU058_01725	COG1192	Involved in chromosome partitioning
KU058_01755	COG0833	amino acid
KU058_01760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KU058_01765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KU058_01775	COG1012	belongs to the aldehyde dehydrogenase family
KU058_01815	COG0583	DNA-binding transcription factor activity
KU058_01860	COG0517	IMP dehydrogenase activity
KU058_01865	COG1983	PspC domain protein
KU058_01875	COG1960	acyl-CoA dehydrogenase activity
KU058_01890	COG0408	coproporphyrinogen oxidase activity
KU058_01910	COG0513	Belongs to the DEAD box helicase family
KU058_01920	COG1127	ABC transporter
KU058_01925	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KU058_01935	COG2854	intermembrane phospholipid transfer
KU058_01945	COG0598	Magnesium transport protein CorA
KU058_01955	COG0494	nUDIX hydrolase
KU058_01960	COG1040	competence protein
KU058_01965	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KU058_01985	COG1946	Acyl-CoA thioesterase
KU058_01990	COG1301	dicarboxylic acid transport
KU058_02005	COG1959	2 iron, 2 sulfur cluster binding
KU058_02010	COG1017	nitric oxide dioxygenase activity
KU058_02010	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU058_02015	COG0433	COG0433 Predicted ATPase
KU058_02020	COG0626	cystathionine gamma-synthase activity
KU058_02175	COG1960	acyl-CoA dehydrogenase activity
KU058_02180	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KU058_02210	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KU058_02215	COG0339	signal peptide processing
KU058_02220	COG0557	exoribonuclease II activity
KU058_02265	COG0179	Fumarylacetoacetate (FAA) hydrolase
KU058_02270	COG2169	Transcriptional regulator
KU058_02275	COG0697	spore germination
KU058_02280	COG1295	ribonuclease BN
KU058_02315	COG1702	phosphate starvation-inducible protein PhoH
KU058_02325	COG0739	heme binding
KU058_02325	COG0741	lytic transglycosylase activity
KU058_02325	COG1196	nuclear chromosome segregation
KU058_02355	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KU058_02360	COG1183	phosphatidylcholine synthase activity
KU058_02405	COG1960	acyl-CoA dehydrogenase activity
KU058_02410	COG1309	transcriptional regulator
KU058_02425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KU058_02430	COG1960	acyl-CoA dehydrogenase activity
KU058_02450	COG2969	positive regulation of protein catabolic process
KU058_02460	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KU058_02475	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KU058_02480	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KU058_02500	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KU058_02510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KU058_02515	COG1408	metallophosphoesterase
KU058_02525	COG2199	diguanylate cyclase activity
KU058_02585	COG1607	acyl-coa hydrolase
KU058_02615	COG2350	Protein conserved in bacteria
KU058_02625	COG0613	PHP domain protein
KU058_02630	COG3781	membrane
KU058_02640	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KU058_02645	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KU058_02655	COG1862	Preprotein translocase
KU058_02685	COG2205	protein histidine kinase activity
KU058_02690	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KU058_02710	COG0726	polysaccharide deacetylase
KU058_02715	COG0463	Glycosyl transferase, family 2
KU058_02720	COG0438	transferase activity, transferring glycosyl groups
KU058_02785	COG0625	glutathione transferase activity
KU058_02790	COG0583	DNA-binding transcription factor activity
KU058_02795	COG1960	acyl-CoA dehydrogenase activity
KU058_02800	COG1960	acyl-CoA dehydrogenase activity
KU058_02810	COG2205	protein histidine kinase activity
KU058_02815	COG0745	RESPONSE REGULATOR receiver
KU058_02820	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KU058_02840	COG2096	Adenosyltransferase
KU058_02890	COG0285	dihydrofolate synthase activity
KU058_02910	COG0450	alkyl hydroperoxide reductase
KU058_02925	COG0477	Major facilitator Superfamily
KU058_02930	COG1272	protein, Hemolysin III
KU058_02960	COG0183	Belongs to the thiolase family
KU058_02965	COG2207	Transcriptional regulator
KU058_02985	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU058_03005	COG0183	Belongs to the thiolase family
KU058_03015	COG2885	chlorophyll binding
KU058_03015	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KU058_03025	COG1690	Belongs to the RtcB family
KU058_03030	COG0833	amino acid
KU058_03040	COG2233	PERMEase
KU058_03045	COG1217	gtp-binding protein TYPA
KU058_03070	COG2094	Belongs to the DNA glycosylase MPG family
KU058_03075	COG4772	TonB-dependent receptor
KU058_03090	COG1902	pentaerythritol trinitrate reductase activity
KU058_03105	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KU058_03110	COG0354	folic acid binding
KU058_03120	COG3189	MarR family transcriptional regulator
KU058_03125	COG2824	Alkylphosphonate utilization operon protein PhnA
KU058_03130	COG3422	double-strand break repair
KU058_03170	COG0840	transmembrane signaling receptor activity
KU058_03190	COG5510	response to toxic substance
KU058_03200	COG2832	Protein of unknown function (DUF454)
KU058_03205	COG1376	ErfK ybiS ycfS ynhG family protein
KU058_03245	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KU058_03255	COG1289	transmembrane transporter activity
KU058_03260	COG2814	Major facilitator Superfamily
KU058_03280	COG1115	amino acid carrier protein
KU058_03285	COG1752	Esterase of the alpha-beta hydrolase superfamily
KU058_03290	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KU058_03295	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
KU058_03325	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KU058_03335	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KU058_03340	COG1077	Cell shape determining protein MreB Mrl
KU058_03345	COG1792	Involved in formation and maintenance of cell shape
KU058_03350	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KU058_03355	COG0424	maF-like protein
KU058_03360	COG1530	ribonuclease E activity
KU058_03370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KU058_03380	COG0560	Phosphoserine phosphatase
KU058_03390	COG2249	NAD(P)H dehydrogenase (quinone) activity
KU058_03415	COG2207	Transcriptional regulator
KU058_03435	COG1113	amino acid transport
KU058_03440	COG2828	Protein conserved in bacteria
KU058_03445	COG0142	geranyltranstransferase activity
KU058_03450	COG2315	Protein conserved in bacteria
KU058_03465	COG1752	Esterase of the alpha-beta hydrolase superfamily
KU058_03485	COG2194	sulfuric ester hydrolase activity
KU058_03490	COG0745	RESPONSE REGULATOR receiver
KU058_03495	COG0642	Histidine kinase
KU058_03505	COG0004	ammonium transporteR
KU058_03510	COG0583	DNA-binding transcription factor activity
KU058_03530	COG0525	valine-tRNA ligase activity
KU058_03540	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_03550	COG0393	Putative heavy-metal-binding
KU058_03555	COG0393	Putative heavy-metal-binding
KU058_03560	COG1538	Outer membrane efflux protein
KU058_03570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU058_03575	COG0671	phosphoesterase, PA-phosphatase related
KU058_03605	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KU058_03620	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KU058_03620	COG1648	precorrin-2 dehydrogenase activity
KU058_03625	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KU058_03630	COG1733	regulation of RNA biosynthetic process
KU058_03640	COG0531	amino acid
KU058_03655	COG0321	lipoyl(octanoyl) transferase activity
KU058_03660	COG2921	Belongs to the UPF0250 family
KU058_03700	COG2009	succinate dehydrogenase
KU058_03705	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KU058_03710	COG1053	succinate dehydrogenase
KU058_03715	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KU058_03740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KU058_03760	COG2354	Protein conserved in bacteria
KU058_03765	COG2321	neutral zinc metallopeptidase
KU058_03800	COG2843	Capsule synthesis protein
KU058_03815	COG0589	response to stress
KU058_03835	COG0505	Belongs to the CarA family
KU058_03860	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KU058_03865	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KU058_03915	COG0477	Major facilitator Superfamily
KU058_03920	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KU058_03935	COG1597	lipid kinase activity
KU058_03940	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KU058_03970	COG0584	glycerophosphoryl diester phosphodiesterase
KU058_03990	COG0741	lytic transglycosylase activity
KU058_04010	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KU058_04025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KU058_04050	COG0778	Nitroreductase
KU058_04065	COG1929	Belongs to the glycerate kinase type-1 family
KU058_04070	COG0243	molybdopterin cofactor binding
KU058_04075	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KU058_04080	COG3339	Conserved Protein
KU058_04090	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KU058_04105	COG1113	amino acid transport
KU058_04115	COG0019	diaminopimelate decarboxylase activity
KU058_04125	COG1280	lysine exporter protein (LysE YggA)
KU058_04130	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KU058_04160	COG0463	Glycosyl transferase, family 2
KU058_04180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU058_04215	COG4591	ABC-type transport system involved in lipoprotein release permease component
KU058_04220	COG1136	(ABC) transporter
KU058_04225	COG0658	competence protein
KU058_04225	COG2333	competence protein COMEC
KU058_04235	COG0616	signal peptide processing
KU058_04235	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KU058_04240	COG0596	Alpha beta hydrolase
KU058_04245	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KU058_04255	COG0628	permease
KU058_04290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KU058_04310	COG0823	Involved in the tonB-independent uptake of proteins
KU058_04330	COG0824	Thioesterase
KU058_04335	COG1473	amidohydrolase
KU058_04355	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KU058_04355	COG0047	phosphoribosylformylglycinamidine synthase activity
KU058_04360	COG2814	Major facilitator Superfamily
KU058_04370	COG1024	Enoyl-CoA hydratase
KU058_04375	COG1051	belongs to the nudix hydrolase family
KU058_04375	COG1056	cytidyltransferase-related domain
KU058_04385	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KU058_04400	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KU058_04415	COG4625	pathogenesis
KU058_04420	COG0583	DNA-binding transcription factor activity
KU058_04425	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KU058_04430	COG4208	sulfate ABC transporter
KU058_04435	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KU058_04445	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KU058_04450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KU058_04455	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KU058_04475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KU058_04490	COG0681	Belongs to the peptidase S26 family
KU058_04505	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KU058_04515	COG1381	Involved in DNA repair and RecF pathway recombination
KU058_04520	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KU058_04530	COG4221	oxidoreductase activity
KU058_04560	COG0436	Aminotransferase
KU058_04580	COG0556	nucleotide-excision repair
KU058_04635	COG2070	2-Nitropropane dioxygenase
KU058_04665	COG1215	transferase activity, transferring glycosyl groups
KU058_04680	COG0415	Belongs to the DNA photolyase family
KU058_04690	COG1252	NADH dehydrogenase
KU058_04695	COG1686	Belongs to the peptidase S11 family
KU058_04710	COG1187	pseudouridine synthase activity
KU058_04735	COG0477	Major facilitator Superfamily
KU058_04740	COG0583	DNA-binding transcription factor activity
KU058_04745	COG1823	symporter activity
KU058_04755	COG0612	Peptidase, M16
KU058_04780	COG0352	thiamine-phosphate diphosphorylase activity
KU058_04815	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU058_04830	COG1309	transcriptional regulator
KU058_04840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KU058_04845	COG0076	glutamate decarboxylase activity
KU058_04855	COG1522	sequence-specific DNA binding
KU058_04860	COG3961	Belongs to the TPP enzyme family
KU058_04865	COG1113	amino acid transport
KU058_04870	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KU058_04875	COG0573	inorganic phosphate transmembrane transporter activity
KU058_04885	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KU058_04890	COG0616	signal peptide processing
KU058_04925	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KU058_04930	COG1686	Belongs to the peptidase S11 family
KU058_04955	COG0583	DNA-binding transcription factor activity
KU058_04960	COG1067	ATP-dependent peptidase activity
KU058_05005	COG1966	Carbon starvation protein
KU058_05010	COG2879	small protein
KU058_05110	COG1802	Transcriptional regulator
KU058_05110	COG4626	Terminase
KU058_05115	COG4695	Portal protein
KU058_05235	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KU058_05265	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KU058_05265	COG2508	Transcriptional regulator
KU058_05285	COG1113	amino acid transport
KU058_05290	COG0583	DNA-binding transcription factor activity
KU058_05295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU058_05300	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU058_05310	COG1012	belongs to the aldehyde dehydrogenase family
KU058_05315	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU058_05320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KU058_05320	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KU058_05355	COG2814	Major facilitator Superfamily
KU058_05360	COG4948	Mandelate Racemase Muconate Lactonizing
KU058_05370	COG1309	transcriptional regulator
KU058_05390	COG1741	Belongs to the pirin family
KU058_05400	COG2964	Protein conserved in bacteria
KU058_05415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KU058_05420	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KU058_05425	COG4605	iron ion homeostasis
KU058_05430	COG4604	ABC transporter, ATP-binding protein
KU058_05435	COG4607	ABC-type enterochelin transport system periplasmic component
KU058_05440	COG4774	siderophore transport
KU058_05450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KU058_05455	COG1021	2,3-dihydroxybenzoate-AMP ligase
KU058_05460	COG3433	isochorismatase activity
KU058_05460	COG1535	isochorismatase
KU058_05475	COG1132	(ABC) transporter
KU058_05480	COG1132	(ABC) transporter
KU058_05485	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KU058_05495	COG1169	isochorismate synthase
KU058_05510	COG3739	integral membrane protein
KU058_05535	COG0302	gtp cyclohydrolase
KU058_05545	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KU058_05575	COG0308	aminopeptidase N
KU058_05580	COG0512	Glutamine amidotransferase of anthranilate synthase
KU058_05770	COG5410	chromosome segregation
KU058_05940	COG0582	viral genome integration into host DNA
KU058_05955	COG0174	glutamine synthetase
KU058_05965	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KU058_06000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KU058_06005	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KU058_06010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KU058_06030	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KU058_06035	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KU058_06040	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KU058_06055	COG1960	acyl-CoA dehydrogenase activity
KU058_06060	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KU058_06065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KU058_06075	COG2223	nitrite transmembrane transporter activity
KU058_06085	COG0024	Methionine aminopeptidase
KU058_06090	COG0052	Belongs to the universal ribosomal protein uS2 family
KU058_06105	COG2207	Transcriptional regulator
KU058_06130	COG2951	lytic endotransglycosylase activity
KU058_06135	COG0772	Belongs to the SEDS family
KU058_06150	COG0842	Transport permease protein
KU058_06155	COG1131	(ABC) transporter
KU058_06200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU058_06215	COG4215	(ABC) transporter
KU058_06220	COG4160	amino acid transport
KU058_06225	COG4598	ABC transporter
KU058_06235	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KU058_06240	COG0826	peptidase U32
KU058_06245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU058_06260	COG1720	tRNA m6t6A37 methyltransferase activity
KU058_06270	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KU058_06285	COG0642	Histidine kinase
KU058_06295	COG0494	nUDIX hydrolase
KU058_06305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KU058_06310	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KU058_06315	COG3139	Protein of unknown function (DUF1315)
KU058_06320	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KU058_06325	COG1301	dicarboxylic acid transport
KU058_06330	COG1960	acyl-CoA dehydrogenase activity
KU058_06335	COG2819	hydrolase of the alpha beta superfamily
KU058_06345	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KU058_06355	COG2195	Cleaves the N-terminal amino acid of tripeptides
KU058_06360	COG1234	tRNA 3'-trailer cleavage
KU058_06390	COG2363	Small membrane protein
KU058_06410	COG0513	Belongs to the DEAD box helicase family
KU058_06420	COG0778	Nitroreductase
KU058_06765	COG1286	toxin biosynthetic process
KU058_06790	COG4783	chaperone-mediated protein folding
KU058_06795	COG1610	YqeY-like protein
KU058_06895	COG3111	PFAM Bacterial OB fold (BOF) protein
KU058_06920	COG3243	poly(R)-hydroxyalkanoic acid synthase
KU058_06925	COG0786	glutamate:sodium symporter activity
KU058_06935	COG2186	Transcriptional regulator
KU058_06985	COG0477	Major facilitator Superfamily
KU058_07010	COG2985	domain, Protein
KU058_07020	COG2995	paraquat-inducible protein a
KU058_07025	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KU058_07025	COG3008	intermembrane lipid transfer
KU058_07050	COG1309	transcriptional regulator
KU058_07055	COG1741	Belongs to the pirin family
KU058_07070	COG2072	flavoprotein involved in K transport
KU058_07080	COG2252	PERMEase
KU058_07085	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KU058_07090	COG3038	cytochrome b561
KU058_07100	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KU058_07110	COG0527	aspartate kinase activity
KU058_07150	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KU058_07235	COG1484	DNA-dependent DNA replication
KU058_07480	COG0592	DNA-directed DNA polymerase activity
KU058_07580	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KU058_07605	COG0582	viral genome integration into host DNA
KU058_07615	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KU058_07625	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KU058_07640	COG0667	Aldo Keto reductase
KU058_07660	COG1765	OsmC-like protein
KU058_07675	COG0542	response to heat
KU058_07710	COG2885	chlorophyll binding
KU058_07720	COG0625	glutathione transferase activity
KU058_07725	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KU058_07750	COG3634	alkyl hydroperoxide reductase activity
KU058_07760	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KU058_07770	COG0450	alkyl hydroperoxide reductase
KU058_07775	COG1643	Atp-dependent helicase
KU058_07790	COG2814	Major facilitator Superfamily
KU058_07795	COG3135	benzoate transporter
KU058_07800	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_07805	COG0543	2 iron, 2 sulfur cluster binding
KU058_07805	COG0633	Ferredoxin
KU058_07810	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KU058_07815	COG4638	Rieske (2fe-2S)
KU058_07820	COG0583	DNA-binding transcription factor activity
KU058_07870	COG1570	exodeoxyribonuclease VII activity
KU058_07900	COG1280	lysine exporter protein (LysE YggA)
KU058_07905	COG1278	Cold shock
KU058_07940	COG2814	Major facilitator Superfamily
KU058_07975	COG0517	IMP dehydrogenase activity
KU058_07975	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KU058_07980	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KU058_07990	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KU058_07995	COG1137	ATPase activity
KU058_08000	COG1538	Outer membrane efflux protein
KU058_08030	COG4122	O-methyltransferase activity
KU058_08040	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KU058_08055	COG1522	sequence-specific DNA binding
KU058_08060	COG5006	permease, DMT superfamily
KU058_08070	COG1560	Kdo2-lipid A biosynthetic process
KU058_08080	COG2814	Major facilitator Superfamily
KU058_08100	COG1250	3-hydroxyacyl-CoA dehydrogenase
KU058_08150	COG0583	DNA-binding transcription factor activity
KU058_08155	COG1914	H( )-stimulated, divalent metal cation uptake system
KU058_08175	COG4770	biotin carboxylase activity
KU058_08180	COG0038	chloride channel
KU058_08200	COG1309	transcriptional regulator
KU058_08210	COG1063	alcohol dehydrogenase
KU058_08225	COG0439	Biotin carboxylase
KU058_08230	COG2249	NAD(P)H dehydrogenase (quinone) activity
KU058_08250	COG0864	Transcriptional regulator
KU058_08260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KU058_08265	COG1116	anion transmembrane transporter activity
KU058_08380	COG0590	tRNA wobble adenosine to inosine editing
KU058_08385	COG2807	transmembrane transport
KU058_08400	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KU058_08415	COG0789	Transcriptional regulator
KU058_08425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU058_08445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KU058_08455	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU058_08470	COG1012	belongs to the aldehyde dehydrogenase family
KU058_08475	COG0531	amino acid
KU058_08480	COG1760	l-serine dehydratase
KU058_08485	COG1012	belongs to the aldehyde dehydrogenase family
KU058_08485	COG2030	dehydratase
KU058_08490	COG3396	Phenylacetate-CoA oxygenase
KU058_08495	COG3460	Phenylacetate-CoA oxygenase
KU058_08500	COG3396	Phenylacetate-CoA oxygenase
KU058_08505	COG2151	metal-sulfur cluster biosynthetic enzyme
KU058_08510	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU058_08515	COG1024	Enoyl-CoA hydratase
KU058_08520	COG1024	Enoyl-CoA hydratase
KU058_08525	COG1250	3-hydroxyacyl-CoA dehydrogenase
KU058_08530	COG0183	Belongs to the thiolase family
KU058_08535	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
KU058_08540	COG3327	negative regulation of DNA-templated transcription, initiation
KU058_08550	COG2050	protein possibly involved in aromatic compounds catabolism
KU058_08585	COG0753	catalase activity
KU058_08590	COG3038	cytochrome b561
KU058_08610	COG2267	carboxylic ester hydrolase activity
KU058_08615	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU058_08620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KU058_08625	COG1012	belongs to the aldehyde dehydrogenase family
KU058_08635	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KU058_08645	COG1012	belongs to the aldehyde dehydrogenase family
KU058_08650	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KU058_08655	COG0583	DNA-binding transcription factor activity
KU058_08665	COG1414	Transcriptional regulator
KU058_08670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU058_08680	COG1840	ABC-type Fe3 transport system, periplasmic component
KU058_08685	COG3842	ATPase activity
KU058_08710	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KU058_08715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KU058_08720	COG2814	Major facilitator Superfamily
KU058_08725	COG1960	acyl-CoA dehydrogenase activity
KU058_08740	COG1024	Enoyl-CoA hydratase
KU058_08750	COG2814	Major facilitator Superfamily
KU058_08760	COG0183	Belongs to the thiolase family
KU058_08765	COG1250	3-hydroxyacyl-CoA dehydrogenase
KU058_08770	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_08775	COG1024	Enoyl-CoA hydratase
KU058_08780	COG1960	acyl-CoA dehydrogenase activity
KU058_08785	COG2814	Major facilitator Superfamily
KU058_08790	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KU058_08795	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KU058_08805	COG2814	Major facilitator Superfamily
KU058_08815	COG1960	acyl-CoA dehydrogenase activity
KU058_08830	COG0583	DNA-binding transcription factor activity
KU058_08840	COG4770	biotin carboxylase activity
KU058_08845	COG1024	Enoyl-CoA hydratase
KU058_08850	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KU058_08855	COG1960	acyl-CoA dehydrogenase activity
KU058_08860	COG1309	transcriptional regulator
KU058_08865	COG0318	PFAM AMP-dependent synthetase and ligase
KU058_08890	COG0583	DNA-binding transcription factor activity
KU058_08940	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_08960	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KU058_08980	COG2205	protein histidine kinase activity
KU058_08980	COG0784	Response regulator, receiver
KU058_09000	COG0765	amino acid transport
KU058_09005	COG0765	amino acid transport
KU058_09010	COG1126	abc transporter atp-binding protein
KU058_09015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KU058_09020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KU058_09035	COG1280	lysine exporter protein (LysE YggA)
KU058_09045	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KU058_09050	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KU058_09055	COG1045	serine acetyltransferase
KU058_09070	COG0583	DNA-binding transcription factor activity
KU058_09075	COG0625	glutathione transferase activity
KU058_09080	COG0625	glutathione transferase activity
KU058_09085	COG0583	DNA-binding transcription factor activity
KU058_09095	COG1346	cytolysis
KU058_09115	COG2814	Major facilitator Superfamily
KU058_09125	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
KU058_09130	COG3052	prosthetic group binding
KU058_09150	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KU058_09170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU058_09180	COG1294	oxidase, subunit
KU058_09185	COG1271	oxidase subunit
KU058_09205	COG0477	Major facilitator Superfamily
KU058_09215	COG4521	taurine ABC transporter
KU058_09220	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KU058_09225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU058_09230	COG2175	clavaminate synthase activity
KU058_09240	COG1953	Uracil, thiamine, allantoin
KU058_09250	COG0583	DNA-binding transcription factor activity
KU058_09260	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KU058_09275	COG0640	Transcriptional regulator
KU058_09280	COG0798	PFAM Bile acid sodium symporter
KU058_09285	COG0583	DNA-binding transcription factor activity
KU058_09300	COG3634	alkyl hydroperoxide reductase activity
KU058_09340	COG0436	Aminotransferase
KU058_09350	COG0386	Belongs to the glutathione peroxidase family
KU058_09390	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KU058_09415	COG0012	GTP binding
KU058_09420	COG2011	ABC-type metal ion transport system permease component
KU058_09425	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KU058_09435	COG1464	Belongs to the NlpA lipoprotein family
KU058_09465	COG0765	amino acid transport
KU058_09470	COG0765	amino acid transport
KU058_09475	COG1126	abc transporter atp-binding protein
KU058_09490	COG1522	sequence-specific DNA binding
KU058_09505	COG1309	transcriptional regulator
KU058_09525	COG0583	DNA-binding transcription factor activity
KU058_09535	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KU058_09545	COG0697	spore germination
KU058_09570	COG3121	Chaperone
KU058_09575	COG3539	Fimbrial protein
KU058_09600	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KU058_09600	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KU058_09645	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KU058_09655	COG2353	YceI-like domain
KU058_09665	COG3698	Phosphodiester glycosidase
KU058_09680	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KU058_09685	COG0506	proline dehydrogenase activity
KU058_09685	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KU058_09685	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KU058_09695	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KU058_09700	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KU058_09720	COG1132	(ABC) transporter
KU058_09725	COG3122	Protein conserved in bacteria
KU058_09730	COG3619	membrane
KU058_09740	COG0640	Transcriptional regulator
KU058_09750	COG2850	peptidyl-arginine hydroxylation
KU058_09755	COG0424	maF-like protein
KU058_09775	COG0191	fructose-bisphosphate aldolase activity
KU058_09780	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KU058_09795	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KU058_09805	COG1192	Involved in chromosome partitioning
KU058_09810	COG1475	DNA binding
KU058_09815	COG0811	peptide transport
KU058_09825	COG1132	(ABC) transporter
KU058_09830	COG1663	tetraacyldisaccharide 4'-kinase activity
KU058_09850	COG0084	hydrolase, TatD family'
KU058_09915	COG0776	regulation of translation
KU058_09945	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KU058_09950	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KU058_10000	COG0339	signal peptide processing
KU058_10010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KU058_10045	COG0702	epimerase
KU058_10050	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KU058_10080	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KU058_10110	COG0316	Belongs to the HesB IscA family
KU058_10115	COG0822	iron-sulfur transferase activity
KU058_10140	COG0776	regulation of translation
KU058_10145	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KU058_10150	COG2207	Transcriptional regulator
KU058_10155	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KU058_10160	COG1960	acyl-CoA dehydrogenase activity
KU058_10165	COG1960	acyl-CoA dehydrogenase activity
KU058_10180	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KU058_10200	COG4264	IucA IucC family
KU058_10205	COG4264	IucA IucC family
KU058_10245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KU058_10260	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KU058_10280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KU058_10285	COG0730	response to heat
KU058_10305	COG4773	Receptor
KU058_10310	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KU058_10325	COG1131	(ABC) transporter
KU058_10330	COG0842	Transport permease protein
KU058_10335	COG0842	Transport permease protein
KU058_10390	COG2226	methyltransferase
KU058_10415	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KU058_10450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KU058_10460	COG0133	tryptophan synthase activity
KU058_10475	COG3706	GGDEF domain
KU058_10490	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KU058_10495	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KU058_10500	COG0022	dehydrogenase e1 component
KU058_10505	COG0508	dehydrogenase complex catalyzes the overall conversion of
KU058_10510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KU058_10520	COG1063	alcohol dehydrogenase
KU058_10525	COG3781	membrane
KU058_10535	COG3453	Protein conserved in bacteria
KU058_10535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KU058_10545	COG0730	response to heat
KU058_10560	COG3708	Transcriptional regulator
KU058_10560	COG2207	Transcriptional regulator
KU058_10565	COG1733	regulation of RNA biosynthetic process
KU058_10570	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KU058_10580	COG2188	Transcriptional regulator
KU058_10595	COG4521	taurine ABC transporter
KU058_10600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU058_10620	COG0477	Major facilitator Superfamily
KU058_10630	COG1027	Aspartate ammonia-lyase
KU058_10645	COG0583	DNA-binding transcription factor activity
KU058_10650	COG0583	DNA-binding transcription factor activity
KU058_10655	COG0183	Belongs to the thiolase family
KU058_10660	COG2031	fatty acid transporter
KU058_10665	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KU058_10675	COG0583	DNA-binding transcription factor activity
KU058_10685	COG2610	gluconate transmembrane transporter activity
KU058_10690	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_10700	COG2207	Transcriptional regulator
KU058_10715	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_10740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU058_10740	COG0543	2 iron, 2 sulfur cluster binding
KU058_10745	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KU058_10750	COG4638	Rieske (2fe-2S)
KU058_10760	COG0725	ABC transporter, periplasmic molybdate-binding protein
KU058_10765	COG4149	molybdate abc transporter
KU058_10770	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KU058_10860	COG4397	Mu-like prophage major head subunit gpT
KU058_10875	COG5005	Phage virion morphogenesis
KU058_10880	COG2369	cell adhesion
KU058_10885	COG4383	Mu-like prophage protein gp29
KU058_10900	COG4373	Mu-like prophage FluMu protein gp28
KU058_10935	COG0681	Belongs to the peptidase S26 family
KU058_10965	COG3267	Type II secretory pathway component ExeA
KU058_10965	COG3409	Peptidoglycan-binding domain 1 protein
KU058_11035	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_11040	COG3433	isochorismatase activity
KU058_11040	COG1535	isochorismatase
KU058_11100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KU058_11115	COG0753	catalase activity
KU058_11125	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KU058_11155	COG3539	Fimbrial protein
KU058_11275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KU058_11295	COG2072	flavoprotein involved in K transport
KU058_11305	COG1538	Outer membrane efflux protein
KU058_11310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KU058_11315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU058_11320	COG0745	RESPONSE REGULATOR receiver
KU058_11325	COG2205	protein histidine kinase activity
KU058_11340	COG2207	Transcriptional regulator
KU058_11355	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_11405	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KU058_11520	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KU058_11540	COG1120	ATPase activity
KU058_11545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KU058_11555	COG1064	alcohol dehydrogenase
KU058_11570	COG2207	Transcriptional regulator
KU058_11575	COG2084	Dehydrogenase
KU058_11585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KU058_11590	COG0583	DNA-binding transcription factor activity
KU058_11600	COG0129	dihydroxy-acid dehydratase activity
KU058_11605	COG1012	belongs to the aldehyde dehydrogenase family
KU058_11620	COG1566	PFAM secretion protein HlyD family protein
KU058_11640	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KU058_11670	COG0583	DNA-binding transcription factor activity
KU058_11685	COG2188	Transcriptional regulator
KU058_11715	COG3210	domain, Protein
KU058_11720	COG2831	hemolysin activation secretion protein
KU058_11730	COG1473	amidohydrolase
KU058_11740	COG0475	glutathione-regulated potassium exporter activity
KU058_11740	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KU058_11750	COG0583	DNA-binding transcription factor activity
KU058_11755	COG1335	isochorismatase
KU058_11765	COG1309	transcriptional regulator
KU058_11795	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KU058_11805	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU058_11805	COG1902	pentaerythritol trinitrate reductase activity
KU058_11810	COG1846	Transcriptional regulator
KU058_11830	COG0753	catalase activity
KU058_11845	COG1012	belongs to the aldehyde dehydrogenase family
KU058_11870	COG3162	membrane
KU058_11880	COG3829	transcription factor binding
KU058_11885	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_11890	COG1960	acyl-CoA dehydrogenase activity
KU058_11910	COG1012	belongs to the aldehyde dehydrogenase family
KU058_11930	COG2186	Transcriptional regulator
KU058_11940	COG0583	DNA-binding transcription factor activity
KU058_11945	COG4948	Mandelate Racemase Muconate Lactonizing
KU058_11950	COG4829	muconolactone delta-isomerase
KU058_11960	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KU058_11965	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KU058_11970	COG0183	Belongs to the thiolase family
KU058_11975	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KU058_11985	COG1012	belongs to the aldehyde dehydrogenase family
KU058_11995	COG3733	amine oxidase
KU058_12005	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU058_12015	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_12025	COG4638	Rieske (2fe-2S)
KU058_12045	COG0154	amidase activity
KU058_12055	COG2814	Major facilitator Superfamily
KU058_12080	COG1960	acyl-CoA dehydrogenase activity
KU058_12085	COG0583	DNA-binding transcription factor activity
KU058_12090	COG1414	Transcriptional regulator
KU058_12105	COG2391	methyltransferase activity
KU058_12115	COG4993	Dehydrogenase
KU058_12120	COG3659	wide pore channel activity
KU058_12125	COG3420	alginic acid biosynthetic process
KU058_12130	COG0710	3-dehydroquinate dehydratase activity
KU058_12135	COG3485	protocatechuate 3,4-dioxygenase
KU058_12140	COG3485	protocatechuate 3,4-dioxygenase
KU058_12145	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KU058_12150	COG2271	Major facilitator Superfamily
KU058_12155	COG0596	Alpha beta hydrolase
KU058_12160	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KU058_12165	COG0183	Belongs to the thiolase family
KU058_12170	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KU058_12175	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KU058_12185	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KU058_12190	COG2323	membrane
KU058_12235	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU058_12235	COG1902	pentaerythritol trinitrate reductase activity
KU058_12260	COG0542	response to heat
KU058_12265	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KU058_12295	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KU058_12300	COG0569	domain protein
KU058_12305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KU058_12320	COG4774	siderophore transport
KU058_12325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KU058_12335	COG1585	Membrane protein implicated in regulation of membrane protease activity
KU058_12355	COG1294	oxidase, subunit
KU058_12360	COG4890	Cyd operon protein YbgT
KU058_12375	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
KU058_12385	COG0552	protein localization to endoplasmic reticulum
KU058_12410	COG0516	GMP reductase activity
KU058_12410	COG0517	IMP dehydrogenase activity
KU058_12415	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KU058_12420	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KU058_12430	COG0583	DNA-binding transcription factor activity
KU058_12435	COG0024	Methionine aminopeptidase
KU058_12465	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KU058_12465	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KU058_12470	COG1105	Belongs to the carbohydrate kinase PfkB family
KU058_12475	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KU058_12475	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KU058_12475	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KU058_12495	COG3300	MHYT domain
KU058_12495	COG5001	Diguanylate cyclase
KU058_12510	COG2135	peptidase activity
KU058_12515	COG0659	secondary active sulfate transmembrane transporter activity
KU058_12530	COG1113	amino acid transport
KU058_12540	COG1522	sequence-specific DNA binding
KU058_12565	COG1011	Hydrolase
KU058_12570	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KU058_12580	COG2137	regulation of response to DNA damage stimulus
KU058_12595	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KU058_12630	COG0575	Belongs to the CDS family
KU058_12635	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KU058_12655	COG3852	Histidine kinase
KU058_12660	COG2204	response regulator
KU058_12725	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KU058_12730	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KU058_12750	COG0697	spore germination
KU058_12755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU058_12765	COG0303	'Molybdopterin
KU058_12770	COG0315	cyclic pyranopterin monophosphate synthase activity
KU058_12770	COG0521	Mo-molybdopterin cofactor biosynthetic process
KU058_12785	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KU058_12790	COG0243	molybdopterin cofactor binding
KU058_12800	COG0243	molybdopterin cofactor binding
KU058_12805	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU058_12810	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU058_12810	COG2146	nitrite reductase [NAD(P)H] activity
KU058_12820	COG0745	RESPONSE REGULATOR receiver
KU058_12825	COG1116	anion transmembrane transporter activity
KU058_12825	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KU058_12845	COG0511	ligase activity, forming carbon-carbon bonds
KU058_12860	COG2814	Major facilitator Superfamily
KU058_12930	COG0741	lytic transglycosylase activity
KU058_12930	COG0739	heme binding
KU058_12930	COG1196	nuclear chromosome segregation
KU058_13075	COG5410	chromosome segregation
KU058_13160	COG4197	protein conserved in bacteria, prophage-related
KU058_13165	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KU058_13235	COG0069	glutamate synthase activity
KU058_13255	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KU058_13265	COG1454	alcohol dehydrogenase
KU058_13270	COG0824	Thioesterase
KU058_13280	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KU058_13295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KU058_13300	COG2030	dehydratase
KU058_13310	COG0183	Belongs to the thiolase family
KU058_13320	COG0583	DNA-binding transcription factor activity
KU058_13325	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KU058_13335	COG1522	sequence-specific DNA binding
KU058_13340	COG3135	benzoate transporter
KU058_13350	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KU058_13375	COG0589	response to stress
KU058_13380	COG0488	(ABC) transporter
KU058_13400	COG4773	Receptor
KU058_13435	COG0668	transmembrane transport
KU058_13445	COG1309	transcriptional regulator
KU058_13460	COG1605	Chorismate mutase
KU058_13470	COG4221	oxidoreductase activity
KU058_13480	COG0308	aminopeptidase N
KU058_13500	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
KU058_13510	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KU058_13515	COG1454	alcohol dehydrogenase
KU058_13535	COG0531	amino acid
KU058_13540	COG4303	Ethanolamine ammonia lyase large subunit
KU058_13545	COG4302	ethanolamine ammonia-lyase activity
KU058_13550	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KU058_13550	COG0519	Catalyzes the synthesis of GMP from XMP
KU058_13555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KU058_13565	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KU058_13580	COG0697	spore germination
KU058_13585	COG1923	regulation of RNA biosynthetic process
KU058_13595	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KU058_13600	COG0802	atpase or kinase
KU058_13620	COG1187	pseudouridine synthase activity
KU058_13635	COG0583	DNA-binding transcription factor activity
KU058_13650	COG2814	Major facilitator Superfamily
KU058_13655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KU058_13680	COG0729	surface antigen
KU058_13700	COG0174	glutamine synthetase
KU058_13705	COG0745	RESPONSE REGULATOR receiver
KU058_13710	COG2205	protein histidine kinase activity
KU058_13720	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KU058_13725	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KU058_13750	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU058_13755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KU058_13760	COG1960	acyl-CoA dehydrogenase activity
KU058_13775	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KU058_13780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU058_13800	COG0583	DNA-binding transcription factor activity
KU058_13815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KU058_13825	COG3658	cytochrome
KU058_13830	COG1215	transferase activity, transferring glycosyl groups
KU058_13835	COG0726	polysaccharide deacetylase
KU058_13835	COG1649	PFAM Uncharacterised BCR, COG1649
KU058_13860	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KU058_13865	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KU058_13875	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KU058_13900	COG0305	Participates in initiation and elongation during chromosome replication
KU058_13905	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KU058_13915	COG1305	Transglutaminase-like
KU058_13925	COG2308	Evidence 4 Homologs of previously reported genes of
KU058_13955	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KU058_13960	COG0138	bifunctional purine biosynthesis protein purh
KU058_13965	COG0151	Belongs to the GarS family
KU058_13970	COG1464	Belongs to the NlpA lipoprotein family
KU058_13975	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KU058_13980	COG2011	ABC-type metal ion transport system permease component
KU058_13985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KU058_13995	COG1301	dicarboxylic acid transport
KU058_14035	COG4269	membrane
KU058_14050	COG1902	pentaerythritol trinitrate reductase activity
KU058_14050	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU058_14060	COG2203	Gaf domain
KU058_14060	COG3706	GGDEF domain
KU058_14060	COG4251	negative regulation of phosphorylation
KU058_14060	COG5001	Diguanylate cyclase
KU058_14070	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KU058_14090	COG4172	Belongs to the ABC transporter superfamily
KU058_14095	COG4239	(ABC) transporter, permease
KU058_14100	COG4174	ABC transporter (Permease)
KU058_14110	COG0741	lytic transglycosylase activity
KU058_14110	COG1388	LysM domain
KU058_14110	COG0741	lytic transglycosylase activity
KU058_14110	COG1388	LysM domain
KU058_14115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KU058_14155	COG0583	DNA-binding transcription factor activity
KU058_14160	COG1279	arginine transmembrane transporter activity
KU058_14180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU058_14185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU058_14190	COG0006	proline dipeptidase activity
KU058_14275	COG0739	heme binding
KU058_14275	COG1196	nuclear chromosome segregation
KU058_14275	COG0741	lytic transglycosylase activity
KU058_14335	COG4695	Portal protein
KU058_14430	COG0305	Participates in initiation and elongation during chromosome replication
KU058_14445	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KU058_14500	COG2194	sulfuric ester hydrolase activity
KU058_14545	COG0739	heme binding
KU058_14870	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KU058_14895	COG3384	dioxygenase
KU058_14905	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KU058_14910	COG2878	Part of a membrane complex involved in electron transport
KU058_14915	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KU058_14940	COG0768	penicillin binding
KU058_14945	COG0742	ribosomal rna small subunit methyltransferase
KU058_14960	COG0830	nickel cation binding
KU058_15005	COG1253	flavin adenine dinucleotide binding
KU058_15010	COG2851	Citrate transporter
KU058_15060	COG1773	rubredoxin
KU058_15065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU058_15075	COG0583	DNA-binding transcription factor activity
KU058_15100	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KU058_15105	COG4181	ATPase activity
KU058_15150	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KU058_15170	COG0306	phosphate transporter
KU058_15180	COG3958	Transketolase
KU058_15185	COG3959	Transketolase, thiamine diphosphate binding domain
KU058_15190	COG2271	Major facilitator Superfamily
KU058_15195	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_15200	COG0583	DNA-binding transcription factor activity
KU058_15215	COG2223	nitrite transmembrane transporter activity
KU058_15220	COG2207	Transcriptional regulator
KU058_15225	COG2066	Belongs to the glutaminase family
KU058_15230	COG0242	peptide deformylase activity
KU058_15235	COG0477	Major facilitator Superfamily
KU058_15245	COG0028	Belongs to the TPP enzyme family
KU058_15260	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_15265	COG2267	carboxylic ester hydrolase activity
KU058_15275	COG2271	Major facilitator Superfamily
KU058_15280	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU058_15290	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_15310	COG1414	Transcriptional regulator
KU058_15325	COG1024	Enoyl-CoA hydratase
KU058_15335	COG1215	transferase activity, transferring glycosyl groups
KU058_15340	COG0726	polysaccharide deacetylase
KU058_15340	COG1649	PFAM Uncharacterised BCR, COG1649
KU058_15350	COG4681	YaeQ
KU058_15360	COG0523	cobalamin synthesis protein
KU058_15370	COG1607	acyl-coa hydrolase
KU058_15380	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU058_15385	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU058_15390	COG1309	transcriptional regulator
KU058_15415	COG2040	homocysteine
KU058_15420	COG0531	amino acid
KU058_15475	COG1595	DNA-templated transcription, initiation
KU058_15485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU058_15490	COG0477	Major facilitator Superfamily
KU058_15510	COG0084	hydrolase, TatD family'
KU058_15545	COG0629	single-stranded DNA binding
KU058_15600	COG0582	viral genome integration into host DNA
KU058_15630	COG1061	Type III restriction enzyme res subunit
KU058_15640	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KU058_15645	COG1192	Involved in chromosome partitioning
KU058_15750	COG0592	DNA-directed DNA polymerase activity
KU058_15790	COG2026	Addiction module toxin, RelE StbE family
KU058_15940	COG3755	Protein conserved in bacteria
KU058_15985	COG1484	DNA-dependent DNA replication
KU058_16075	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KU058_16145	COG0405	Gamma-glutamyltransferase
KU058_16150	COG2814	Major facilitator Superfamily
KU058_16160	COG2050	protein possibly involved in aromatic compounds catabolism
KU058_16175	COG1090	epimerase
KU058_16195	COG0420	3'-5' exonuclease activity
KU058_16220	COG0735	belongs to the Fur family
KU058_16225	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KU058_16245	COG0121	glutamine amidotransferase
KU058_16260	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KU058_16270	COG0210	DNA helicase
KU058_16275	COG2885	chlorophyll binding
KU058_16280	COG0204	Acyl-transferase
KU058_16295	COG2894	cell division
KU058_16320	COG1280	lysine exporter protein (LysE YggA)
KU058_16325	COG1674	ftsk spoiiie
KU058_16325	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KU058_16330	COG0492	ferredoxin-NADP+ reductase activity
KU058_16335	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KU058_16345	COG0456	acetyltransferase
KU058_16390	COG1981	membrane
KU058_16405	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KU058_16405	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KU058_16425	COG1012	belongs to the aldehyde dehydrogenase family
KU058_16435	COG0657	acetylesterase activity
KU058_16445	COG0473	3-isopropylmalate dehydrogenase activity
KU058_16450	COG0583	DNA-binding transcription factor activity
KU058_16470	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KU058_16495	COG0564	pseudouridine synthase activity
KU058_16505	COG0358	DNA primase activity
KU058_16520	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KU058_16550	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KU058_16580	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KU058_16590	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KU058_16590	COG0352	thiamine-phosphate diphosphorylase activity
KU058_16590	COG0351	phosphomethylpyrimidine kinase
KU058_16595	COG1652	LysM domain
KU058_16620	COG1399	metal-binding, possibly nucleic acid-binding protein
KU058_16625	COG3101	peptidyl-lysine hydroxylation
KU058_16630	COG0009	L-threonylcarbamoyladenylate synthase
KU058_16635	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KU058_16640	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KU058_16655	COG4106	trans-aconitate 2-methyltransferase activity
KU058_16670	COG2226	methyltransferase
KU058_16670	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KU058_16670	COG0596	Alpha beta hydrolase
KU058_16675	COG1877	trehalose-phosphatase activity
KU058_16680	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
KU058_16685	COG2223	nitrite transmembrane transporter activity
KU058_16705	COG1196	nuclear chromosome segregation
KU058_16715	COG0730	response to heat
KU058_16730	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KU058_16740	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KU058_16790	COG0489	protein tyrosine kinase activity
KU058_16800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KU058_16800	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KU058_16830	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KU058_16835	COG2081	HI0933 family
KU058_16845	COG0668	transmembrane transport
KU058_16865	COG0583	DNA-binding transcription factor activity
KU058_16885	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KU058_16890	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KU058_16920	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KU058_16960	COG0745	RESPONSE REGULATOR receiver
KU058_16980	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KU058_17015	COG0384	phenazine biosynthesis protein PhzF
KU058_17035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU058_17050	COG0583	DNA-binding transcription factor activity
KU058_17080	COG0583	DNA-binding transcription factor activity
KU058_17095	COG0583	DNA-binding transcription factor activity
KU058_17100	COG1053	succinate dehydrogenase
KU058_17110	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KU058_17115	COG2814	Major facilitator Superfamily
KU058_17120	COG1960	acyl-CoA dehydrogenase activity
KU058_17125	COG0583	DNA-binding transcription factor activity
KU058_17130	COG1063	alcohol dehydrogenase
KU058_17160	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KU058_17165	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KU058_17170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KU058_17185	COG3667	copper resistance
KU058_17190	COG2132	Multicopper oxidase
KU058_17200	COG0561	phosphatase activity
KU058_17205	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KU058_17230	COG1214	PFAM Peptidase M22, glycoprotease
KU058_17280	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KU058_17290	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KU058_17295	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KU058_17300	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KU058_17360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KU058_17370	COG1846	Transcriptional regulator
KU058_17375	COG1764	response to oxidative stress
KU058_17415	COG0037	tRNA processing
KU058_17425	COG0248	Ppx GppA phosphatase
KU058_17455	COG0072	phenylalanine-tRNA ligase activity
KU058_17495	COG1238	metal cluster binding
KU058_17500	COG0625	glutathione transferase activity
KU058_17515	COG0318	PFAM AMP-dependent synthetase and ligase
KU058_17520	COG3028	Belongs to the UPF0307 family
KU058_17525	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KU058_17545	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KU058_17550	COG0617	tRNA 3'-terminal CCA addition
KU058_17555	COG1555	photosystem II stabilization
KU058_17560	COG3956	TIGRFAM MazG family protein
KU058_17570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KU058_17590	COG0784	Response regulator, receiver
KU058_17590	COG2205	protein histidine kinase activity
KU058_17590	COG5002	protein histidine kinase activity
KU058_17595	COG1024	Enoyl-CoA hydratase
KU058_17600	COG2084	Dehydrogenase
KU058_17605	COG3622	Belongs to the hyi family
KU058_17635	COG0697	spore germination
KU058_17645	COG2814	Major facilitator Superfamily
KU058_17650	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KU058_17660	COG0583	DNA-binding transcription factor activity
KU058_17670	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KU058_17685	COG0084	hydrolase, TatD family'
KU058_17700	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KU058_17730	COG0440	acetolactate synthase activity
KU058_17735	COG0028	Belongs to the TPP enzyme family
KU058_17760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU058_17765	COG1136	(ABC) transporter
KU058_17765	COG0577	efflux transmembrane transporter activity
KU058_17770	COG1538	Outer membrane efflux protein
KU058_17785	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KU058_17790	COG1162	GTPase activity
KU058_17800	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KU058_17820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KU058_17825	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_17865	COG2986	histidine ammonia-lyase
KU058_17880	COG0318	PFAM AMP-dependent synthetase and ligase
KU058_17890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KU058_17935	COG1426	Protein conserved in bacteria
KU058_17970	COG0793	Belongs to the peptidase S41A family
KU058_17985	COG2267	carboxylic ester hydrolase activity
KU058_17995	COG1012	belongs to the aldehyde dehydrogenase family
KU058_18000	COG3265	gluconokinase activity
KU058_18010	COG0800	Aldolase
KU058_18020	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KU058_18025	COG0280	phosphate acetyltransferase
KU058_18025	COG0857	belongs to the CobB CobQ family
KU058_18030	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KU058_18030	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KU058_18050	COG0740	serine-type endopeptidase activity
KU058_18060	COG4774	siderophore transport
KU058_18070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KU058_18080	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KU058_18080	COG2813	Specifically methylates the guanine in position
KU058_18180	COG0788	formyltetrahydrofolate deformylase activity
KU058_18205	COG4651	solute:proton antiporter activity
KU058_18205	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KU058_18225	COG0724	RNA recognition motif
KU058_18230	COG0210	DNA helicase
KU058_18255	COG1733	regulation of RNA biosynthetic process
KU058_18265	COG2900	Belongs to the SlyX family
KU058_18270	COG0488	(ABC) transporter
KU058_18275	COG1280	lysine exporter protein (LysE YggA)
KU058_18280	COG1560	Kdo2-lipid A biosynthetic process
KU058_18290	COG1301	dicarboxylic acid transport
KU058_18345	COG0473	3-isopropylmalate dehydrogenase activity
KU058_18410	COG0583	DNA-binding transcription factor activity
KU058_18420	COG0625	glutathione transferase activity
KU058_18425	COG2378	regulation of single-species biofilm formation
KU058_18430	COG0546	phosphoglycolate phosphatase activity
KU058_18440	COG1530	ribonuclease E activity
KU058_18445	COG0318	PFAM AMP-dependent synthetase and ligase
KU058_18460	COG0583	DNA-binding transcription factor activity
KU058_18465	COG4221	oxidoreductase activity
KU058_18470	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KU058_18480	COG0534	Mate efflux family protein
KU058_18495	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KU058_18535	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KU058_18540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KU058_18555	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KU058_18565	COG0644	oxidoreductase
KU058_18565	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
KU058_18570	COG0425	Belongs to the sulfur carrier protein TusA family
KU058_18575	COG4535	Mg2 and Co2 transporter CorC
KU058_18585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KU058_18605	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KU058_18610	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KU058_18610	COG0475	glutathione-regulated potassium exporter activity
KU058_18615	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KU058_18625	COG0484	heat shock protein binding
KU058_18630	COG0789	Transcriptional regulator
KU058_18635	COG0598	Magnesium transport protein CorA
KU058_18650	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KU058_18655	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KU058_18660	COG1074	ATP-dependent DNA helicase activity
KU058_18665	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KU058_18685	COG2226	methyltransferase
KU058_18700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU058_18705	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KU058_18720	COG2111	Na H antiporter
KU058_18720	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KU058_18725	COG1006	Multisubunit Na H antiporter MnhC subunit
KU058_18730	COG0651	ATP synthesis coupled electron transport
KU058_18735	COG1863	multisubunit Na H antiporter MnhE subunit
KU058_18740	COG2212	antiporter activity
KU058_18745	COG1320	monovalent cation:proton antiporter activity
KU058_18760	COG0195	Participates in both transcription termination and antitermination
KU058_18810	COG0237	dephospho-CoA kinase activity
KU058_18820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KU058_18835	COG0497	DNA recombination
KU058_18845	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KU058_18875	COG2169	Transcriptional regulator
KU058_18875	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KU058_18880	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KU058_18945	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KU058_18960	COG0326	Molecular chaperone. Has ATPase activity
KU058_18975	COG2056	Na+-H+ antiporter family
KU058_18980	COG0596	Alpha beta hydrolase
KU058_19075	COG0546	phosphoglycolate phosphatase activity
KU058_19080	COG1716	ATPase activity
KU058_19125	COG0181	hydroxymethylbilane synthase activity
KU058_19135	COG3275	phosphorelay sensor kinase activity
KU058_19155	COG1538	Outer membrane efflux protein
KU058_19160	COG0697	spore germination
KU058_19185	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KU058_19190	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KU058_19195	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KU058_19200	COG0772	Belongs to the SEDS family
KU058_19225	COG4974	Belongs to the 'phage' integrase family
KU058_19230	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KU058_19240	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KU058_19250	COG2197	response regulator
KU058_19265	COG0793	Belongs to the peptidase S41A family
KU058_19270	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KU058_19275	COG0795	lipopolysaccharide-transporting ATPase activity
KU058_19315	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KU058_19315	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KU058_19325	COG0004	ammonium transporteR
KU058_19330	COG0347	Belongs to the P(II) protein family
KU058_19340	COG0606	chelatase, subunit chli
KU058_19350	COG0659	secondary active sulfate transmembrane transporter activity
KU058_19355	COG0589	response to stress
KU058_19395	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KU058_19440	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KU058_19475	COG0589	response to stress
KU058_19505	COG0606	chelatase, subunit chli
KU058_19510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU058_19520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU058_19535	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KU058_19550	COG0318	PFAM AMP-dependent synthetase and ligase
KU058_19560	COG0477	Major facilitator Superfamily
KU058_19565	COG2860	membrane
KU058_19575	COG1253	flavin adenine dinucleotide binding
KU058_19595	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KU058_19630	COG0655	NAD(P)H dehydrogenase (quinone) activity
KU058_19640	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KU058_19675	COG1309	transcriptional regulator
KU058_19710	COG0758	DNA mediated transformation
KU058_19720	COG0697	spore germination
KU058_19725	COG1309	transcriptional regulator
KU058_19740	COG0386	Belongs to the glutathione peroxidase family
KU058_19805	COG1121	(ABC) transporter
KU058_19810	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KU058_19815	COG1280	lysine exporter protein (LysE YggA)
KU058_19820	COG2837	iron assimilation
KU058_19830	COG0281	malic enzyme
KU058_19875	COG0519	Catalyzes the synthesis of GMP from XMP
KU058_19875	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KU058_19880	COG4399	Belongs to the UPF0754 family
KU058_19885	COG2259	Doxx family
KU058_19890	COG0586	Pfam SNARE associated Golgi protein
KU058_19905	COG1192	Involved in chromosome partitioning
KU058_19915	COG0271	Belongs to the BolA IbaG family
KU058_19935	COG2267	carboxylic ester hydrolase activity
KU058_19955	COG3321	synthase
KU058_19955	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KU058_19955	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KU058_19955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KU058_19960	COG1960	acyl-CoA dehydrogenase activity
KU058_19970	COG2197	response regulator
KU058_19980	COG3916	Acyl-homoserine-lactone synthase
KU058_19985	COG0477	Major facilitator Superfamily
KU058_19990	COG1024	Enoyl-CoA hydratase
KU058_19995	COG1024	Enoyl-CoA hydratase
KU058_20000	COG1960	acyl-CoA dehydrogenase activity
KU058_20005	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KU058_20025	COG1113	amino acid transport
KU058_20030	COG1113	amino acid transport
KU058_20035	COG0251	oxidation-reduction process
KU058_20075	COG0564	pseudouridine synthase activity
KU058_20135	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KU058_20150	COG1802	Transcriptional regulator
KU058_20160	COG1448	Aminotransferase
KU058_20165	COG0277	FAD linked oxidase domain protein
KU058_20175	COG2186	Transcriptional regulator
KU058_20185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KU058_20190	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KU058_20205	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KU058_20210	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KU058_20235	COG2244	polysaccharide biosynthetic process
KU058_20240	COG1083	cytidylyl-transferase
KU058_20245	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KU058_20255	COG2089	acid synthase
KU058_20260	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KU058_20265	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KU058_20275	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KU058_20280	COG1596	polysaccharide export
KU058_20305	COG0728	peptidoglycan biosynthetic process
KU058_20310	COG3023	N-Acetylmuramoyl-L-alanine amidase
KU058_20365	COG0546	phosphoglycolate phosphatase activity
KU058_20370	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_20390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KU058_20395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KU058_20400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KU058_20405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU058_20410	COG1116	anion transmembrane transporter activity
KU058_20415	COG1309	transcriptional regulator
KU058_20420	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KU058_20430	COG0196	riboflavin kinase activity
KU058_20435	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KU058_20445	COG1047	Peptidyl-prolyl cis-trans
KU058_20485	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KU058_20490	COG0657	acetylesterase activity
KU058_20540	COG2951	lytic endotransglycosylase activity
KU058_20545	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KU058_20560	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KU058_20570	COG0671	phosphoesterase, PA-phosphatase related
KU058_20575	COG0861	Integral membrane protein TerC family
KU058_20585	COG0754	glutathionylspermidine amidase activity
KU058_20595	COG0402	S-adenosylhomocysteine deaminase activity
KU058_20610	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KU058_20615	COG1230	cation diffusion facilitator family transporter
KU058_20630	COG0706	membrane insertase activity
KU058_20665	COG4683	PFAM Phage derived protein Gp49-like (DUF891)