locus-tag	class	description
KU217_00010	COG0592	DNA-directed DNA polymerase activity
KU217_00020	COG0187	DNA topoisomerase II activity
KU217_00030	COG0586	Pfam SNARE associated Golgi protein
KU217_00035	COG0488	(ABC) transporter
KU217_00060	COG0596	Alpha beta hydrolase
KU217_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KU217_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KU217_00110	COG0733	neurotransmitter:sodium symporter activity
KU217_00150	COG2233	PERMEase
KU217_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU217_00200	COG2814	Major facilitator Superfamily
KU217_00205	COG0656	L-ascorbic acid biosynthetic process
KU217_00210	COG0583	DNA-binding transcription factor activity
KU217_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU217_00230	COG1064	alcohol dehydrogenase
KU217_00235	COG2818	Glycosylase
KU217_00250	COG1194	a g-specific adenine glycosylase
KU217_00260	COG0400	carboxylic ester hydrolase activity
KU217_00270	COG2983	Belongs to the UPF0260 family
KU217_00275	COG2133	pyrroloquinoline quinone binding
KU217_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KU217_00285	COG2116	formate transmembrane transporter activity
KU217_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU217_00310	COG1335	isochorismatase
KU217_00315	COG0385	Bile acid
KU217_00320	COG0534	Mate efflux family protein
KU217_00325	COG1683	Conserved Protein
KU217_00345	COG0625	glutathione transferase activity
KU217_00355	COG1113	amino acid transport
KU217_00365	COG0523	cobalamin synthesis protein
KU217_00375	COG2188	Transcriptional regulator
KU217_00405	COG0010	Belongs to the arginase family
KU217_00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KU217_00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KU217_00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KU217_00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KU217_00540	COG0534	Mate efflux family protein
KU217_00545	COG0436	Aminotransferase
KU217_00550	COG2733	membrane
KU217_00565	COG2918	glutathione biosynthetic process
KU217_00580	COG1388	LysM domain
KU217_00580	COG3409	Peptidoglycan-binding domain 1 protein
KU217_00580	COG5632	N-Acetylmuramoyl-L-alanine amidase
KU217_00600	COG3150	esterase
KU217_00610	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
KU217_00620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU217_00630	COG2233	PERMEase
KU217_00635	COG2351	hydroxyisourate hydrolase activity
KU217_00670	COG3706	GGDEF domain
KU217_00685	COG1393	Belongs to the ArsC family
KU217_00690	COG0708	Exodeoxyribonuclease III
KU217_00710	COG0189	ligase activity
KU217_00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KU217_00740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KU217_00755	COG4942	peptidase
KU217_00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
KU217_00775	COG2119	membrane
KU217_00780	COG4774	siderophore transport
KU217_00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU217_00785	COG0426	domain, Protein
KU217_00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KU217_00830	COG1902	pentaerythritol trinitrate reductase activity
KU217_00835	COG1519	Transferase
KU217_00840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KU217_00845	COG0668	transmembrane transport
KU217_00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KU217_00860	COG1335	isochorismatase
KU217_00865	COG1522	sequence-specific DNA binding
KU217_00890	COG0784	Response regulator, receiver
KU217_00890	COG2198	Histidine kinase
KU217_00890	COG2205	protein histidine kinase activity
KU217_00895	COG3162	membrane
KU217_00900	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KU217_00910	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU217_00930	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KU217_00935	COG1309	transcriptional regulator
KU217_00955	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KU217_00955	COG0352	thiamine-phosphate diphosphorylase activity
KU217_00955	COG0351	phosphomethylpyrimidine kinase
KU217_00965	COG2814	Major facilitator Superfamily
KU217_00980	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KU217_00990	COG1113	amino acid transport
KU217_01000	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KU217_01005	COG1012	belongs to the aldehyde dehydrogenase family
KU217_01015	COG1335	isochorismatase
KU217_01045	COG2814	Major facilitator Superfamily
KU217_01050	COG0583	DNA-binding transcription factor activity
KU217_01070	COG0667	Aldo Keto reductase
KU217_01105	COG1733	regulation of RNA biosynthetic process
KU217_01110	COG2249	NAD(P)H dehydrogenase (quinone) activity
KU217_01180	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KU217_01195	COG2329	Antibiotic biosynthesis monooxygenase
KU217_01225	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KU217_01255	COG0427	acetyl-CoA hydrolase
KU217_01280	COG0659	secondary active sulfate transmembrane transporter activity
KU217_01285	COG4221	oxidoreductase activity
KU217_01290	COG2873	o-acetylhomoserine
KU217_01295	COG0488	(ABC) transporter
KU217_01380	COG0833	amino acid
KU217_01425	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KU217_01430	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KU217_01445	COG2226	methyltransferase
KU217_01495	COG0067	glutamate synthase
KU217_01495	COG0069	glutamate synthase activity
KU217_01495	COG0070	glutamate synthase
KU217_01500	COG0493	'glutamate synthase
KU217_01510	COG1704	LemA family
KU217_01515	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KU217_01530	COG3307	-O-antigen
KU217_01550	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KU217_01565	COG0194	GDP metabolic process
KU217_01615	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KU217_01635	COG5380	lipid catabolic process
KU217_01640	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KU217_01665	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KU217_01670	COG0277	FAD linked oxidase domain protein
KU217_01680	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KU217_01685	COG2249	NAD(P)H dehydrogenase (quinone) activity
KU217_01700	COG1289	transmembrane transporter activity
KU217_01710	COG0628	permease
KU217_01715	COG1192	Involved in chromosome partitioning
KU217_01745	COG0833	amino acid
KU217_01750	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KU217_01755	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KU217_01765	COG1012	belongs to the aldehyde dehydrogenase family
KU217_01805	COG0583	DNA-binding transcription factor activity
KU217_01855	COG0517	IMP dehydrogenase activity
KU217_01860	COG1983	PspC domain protein
KU217_01870	COG1960	acyl-CoA dehydrogenase activity
KU217_01885	COG0408	coproporphyrinogen oxidase activity
KU217_01905	COG0513	Belongs to the DEAD box helicase family
KU217_01915	COG1127	ABC transporter
KU217_01920	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KU217_01930	COG2854	intermembrane phospholipid transfer
KU217_01940	COG0598	Magnesium transport protein CorA
KU217_01950	COG0494	nUDIX hydrolase
KU217_01955	COG1040	competence protein
KU217_01960	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KU217_01980	COG1946	Acyl-CoA thioesterase
KU217_01985	COG1301	dicarboxylic acid transport
KU217_02000	COG1959	2 iron, 2 sulfur cluster binding
KU217_02005	COG1017	nitric oxide dioxygenase activity
KU217_02005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU217_02010	COG0433	COG0433 Predicted ATPase
KU217_02015	COG0626	cystathionine gamma-synthase activity
KU217_02170	COG1960	acyl-CoA dehydrogenase activity
KU217_02175	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KU217_02205	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KU217_02210	COG0339	signal peptide processing
KU217_02215	COG0557	exoribonuclease II activity
KU217_02265	COG0179	Fumarylacetoacetate (FAA) hydrolase
KU217_02270	COG2169	Transcriptional regulator
KU217_02275	COG0697	spore germination
KU217_02280	COG1295	ribonuclease BN
KU217_02315	COG1702	phosphate starvation-inducible protein PhoH
KU217_02325	COG0739	heme binding
KU217_02325	COG1196	nuclear chromosome segregation
KU217_02325	COG0741	lytic transglycosylase activity
KU217_02355	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KU217_02360	COG1183	phosphatidylcholine synthase activity
KU217_02405	COG1960	acyl-CoA dehydrogenase activity
KU217_02410	COG1309	transcriptional regulator
KU217_02425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KU217_02430	COG1960	acyl-CoA dehydrogenase activity
KU217_02470	COG2969	positive regulation of protein catabolic process
KU217_02480	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KU217_02495	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KU217_02500	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KU217_02520	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KU217_02530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KU217_02535	COG1408	metallophosphoesterase
KU217_02605	COG1607	acyl-coa hydrolase
KU217_02635	COG2350	Protein conserved in bacteria
KU217_02645	COG0613	PHP domain protein
KU217_02650	COG3781	membrane
KU217_02660	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KU217_02665	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KU217_02675	COG1862	Preprotein translocase
KU217_02710	COG4695	Portal protein
KU217_02730	COG2205	protein histidine kinase activity
KU217_02735	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KU217_02755	COG0726	polysaccharide deacetylase
KU217_02765	COG0438	transferase activity, transferring glycosyl groups
KU217_02830	COG1960	acyl-CoA dehydrogenase activity
KU217_02835	COG1960	acyl-CoA dehydrogenase activity
KU217_02845	COG2205	protein histidine kinase activity
KU217_02850	COG0745	RESPONSE REGULATOR receiver
KU217_02855	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KU217_02875	COG2096	Adenosyltransferase
KU217_02925	COG0285	dihydrofolate synthase activity
KU217_02945	COG0450	alkyl hydroperoxide reductase
KU217_02960	COG0477	Major facilitator Superfamily
KU217_02965	COG1272	protein, Hemolysin III
KU217_02975	COG2153	protein acetylation
KU217_02995	COG0183	Belongs to the thiolase family
KU217_03000	COG2207	Transcriptional regulator
KU217_03020	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU217_03040	COG0183	Belongs to the thiolase family
KU217_03050	COG2885	chlorophyll binding
KU217_03050	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KU217_03060	COG1690	Belongs to the RtcB family
KU217_03065	COG0833	amino acid
KU217_03075	COG2233	PERMEase
KU217_03080	COG1217	gtp-binding protein TYPA
KU217_03105	COG2094	Belongs to the DNA glycosylase MPG family
KU217_03110	COG4772	TonB-dependent receptor
KU217_03115	COG1902	pentaerythritol trinitrate reductase activity
KU217_03130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KU217_03135	COG0354	folic acid binding
KU217_03145	COG3189	MarR family transcriptional regulator
KU217_03150	COG2824	Alkylphosphonate utilization operon protein PhnA
KU217_03155	COG3422	double-strand break repair
KU217_03195	COG0840	transmembrane signaling receptor activity
KU217_03215	COG5510	response to toxic substance
KU217_03225	COG2832	Protein of unknown function (DUF454)
KU217_03230	COG1376	ErfK ybiS ycfS ynhG family protein
KU217_03270	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KU217_03280	COG1289	transmembrane transporter activity
KU217_03285	COG2814	Major facilitator Superfamily
KU217_03305	COG1115	amino acid carrier protein
KU217_03310	COG1752	Esterase of the alpha-beta hydrolase superfamily
KU217_03315	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KU217_03320	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
KU217_03325	COG3590	peptidase
KU217_03350	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KU217_03360	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KU217_03365	COG1077	Cell shape determining protein MreB Mrl
KU217_03370	COG1792	Involved in formation and maintenance of cell shape
KU217_03375	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KU217_03380	COG0424	maF-like protein
KU217_03385	COG1530	ribonuclease E activity
KU217_03395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KU217_03405	COG0560	Phosphoserine phosphatase
KU217_03415	COG2249	NAD(P)H dehydrogenase (quinone) activity
KU217_03440	COG2207	Transcriptional regulator
KU217_03460	COG1113	amino acid transport
KU217_03465	COG2828	Protein conserved in bacteria
KU217_03470	COG0142	geranyltranstransferase activity
KU217_03475	COG2315	Protein conserved in bacteria
KU217_03490	COG1752	Esterase of the alpha-beta hydrolase superfamily
KU217_03510	COG2194	sulfuric ester hydrolase activity
KU217_03515	COG0745	RESPONSE REGULATOR receiver
KU217_03520	COG0642	Histidine kinase
KU217_03530	COG0004	ammonium transporteR
KU217_03535	COG0583	DNA-binding transcription factor activity
KU217_03565	COG0525	valine-tRNA ligase activity
KU217_03575	COG0525	valine-tRNA ligase activity
KU217_03585	COG1028	Short-chain dehydrogenase reductase Sdr
KU217_03595	COG0393	Putative heavy-metal-binding
KU217_03600	COG0393	Putative heavy-metal-binding
KU217_03605	COG1538	Outer membrane efflux protein
KU217_03615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU217_03620	COG0671	phosphoesterase, PA-phosphatase related
KU217_03650	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KU217_03665	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KU217_03665	COG1648	precorrin-2 dehydrogenase activity
KU217_03670	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KU217_03675	COG1733	regulation of RNA biosynthetic process
KU217_03685	COG0531	amino acid
KU217_03700	COG0321	lipoyl(octanoyl) transferase activity
KU217_03705	COG2921	Belongs to the UPF0250 family
KU217_03740	COG2009	succinate dehydrogenase
KU217_03745	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KU217_03750	COG1053	succinate dehydrogenase
KU217_03755	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KU217_03780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KU217_03800	COG2354	Protein conserved in bacteria
KU217_03805	COG2321	neutral zinc metallopeptidase
KU217_03855	COG2843	Capsule synthesis protein
KU217_03870	COG0589	response to stress
KU217_03880	COG0251	oxidation-reduction process
KU217_03885	COG1309	transcriptional regulator
KU217_03900	COG0505	Belongs to the CarA family
KU217_03925	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KU217_03930	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KU217_03980	COG0477	Major facilitator Superfamily
KU217_03985	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KU217_04000	COG1597	lipid kinase activity
KU217_04005	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KU217_04070	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KU217_04075	COG4197	protein conserved in bacteria, prophage-related
KU217_04155	COG5410	chromosome segregation
KU217_04160	COG3567	Phage-associated protein, HI1409 family
KU217_04175	COG3566	protein conserved in bacteria
KU217_04315	COG0582	viral genome integration into host DNA
KU217_04325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KU217_04330	COG0584	glycerophosphoryl diester phosphodiesterase
KU217_04350	COG0741	lytic transglycosylase activity
KU217_04370	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KU217_04385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KU217_04395	COG1204	response to ionizing radiation
KU217_04425	COG0778	Nitroreductase
KU217_04440	COG1929	Belongs to the glycerate kinase type-1 family
KU217_04445	COG0243	molybdopterin cofactor binding
KU217_04450	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KU217_04455	COG3339	Conserved Protein
KU217_04465	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KU217_04480	COG1113	amino acid transport
KU217_04490	COG0019	diaminopimelate decarboxylase activity
KU217_04505	COG2267	carboxylic ester hydrolase activity
KU217_04510	COG1280	lysine exporter protein (LysE YggA)
KU217_04515	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KU217_04545	COG0463	Glycosyl transferase, family 2
KU217_04565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU217_04600	COG4591	ABC-type transport system involved in lipoprotein release permease component
KU217_04605	COG1136	(ABC) transporter
KU217_04610	COG0658	competence protein
KU217_04610	COG2333	competence protein COMEC
KU217_04620	COG0616	signal peptide processing
KU217_04620	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KU217_04625	COG0596	Alpha beta hydrolase
KU217_04630	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KU217_04640	COG0628	permease
KU217_04685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KU217_04705	COG0823	Involved in the tonB-independent uptake of proteins
KU217_04725	COG0824	Thioesterase
KU217_04730	COG1473	amidohydrolase
KU217_04750	COG0047	phosphoribosylformylglycinamidine synthase activity
KU217_04750	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KU217_04755	COG2814	Major facilitator Superfamily
KU217_04765	COG1024	Enoyl-CoA hydratase
KU217_04770	COG1056	cytidyltransferase-related domain
KU217_04770	COG1051	belongs to the nudix hydrolase family
KU217_04780	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KU217_04795	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KU217_04810	COG4625	pathogenesis
KU217_04815	COG0583	DNA-binding transcription factor activity
KU217_04820	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KU217_04825	COG4208	sulfate ABC transporter
KU217_04830	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KU217_04840	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KU217_04845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KU217_04850	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KU217_04870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KU217_04885	COG0681	Belongs to the peptidase S26 family
KU217_04900	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KU217_04910	COG1381	Involved in DNA repair and RecF pathway recombination
KU217_04915	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KU217_04925	COG4221	oxidoreductase activity
KU217_04955	COG0443	Heat shock 70 kDa protein
KU217_04965	COG0436	Aminotransferase
KU217_04985	COG0556	nucleotide-excision repair
KU217_05040	COG2070	2-Nitropropane dioxygenase
KU217_05070	COG1215	transferase activity, transferring glycosyl groups
KU217_05085	COG0415	Belongs to the DNA photolyase family
KU217_05095	COG1252	NADH dehydrogenase
KU217_05100	COG1686	Belongs to the peptidase S11 family
KU217_05115	COG1187	pseudouridine synthase activity
KU217_05140	COG0477	Major facilitator Superfamily
KU217_05145	COG0583	DNA-binding transcription factor activity
KU217_05150	COG1823	symporter activity
KU217_05160	COG0612	Peptidase, M16
KU217_05185	COG0352	thiamine-phosphate diphosphorylase activity
KU217_05220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU217_05235	COG1309	transcriptional regulator
KU217_05245	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KU217_05250	COG0076	glutamate decarboxylase activity
KU217_05260	COG1522	sequence-specific DNA binding
KU217_05265	COG3961	Belongs to the TPP enzyme family
KU217_05270	COG1113	amino acid transport
KU217_05275	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KU217_05280	COG0573	inorganic phosphate transmembrane transporter activity
KU217_05290	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KU217_05295	COG0616	signal peptide processing
KU217_05330	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KU217_05340	COG1686	Belongs to the peptidase S11 family
KU217_05365	COG0583	DNA-binding transcription factor activity
KU217_05370	COG1067	ATP-dependent peptidase activity
KU217_05395	COG4943	cyclic-guanylate-specific phosphodiesterase activity
KU217_05415	COG1966	Carbon starvation protein
KU217_05420	COG2879	small protein
KU217_05460	COG1335	isochorismatase
KU217_05465	COG0583	DNA-binding transcription factor activity
KU217_05480	COG0596	Alpha beta hydrolase
KU217_05490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KU217_05525	COG1741	Belongs to the pirin family
KU217_05535	COG2964	Protein conserved in bacteria
KU217_05550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KU217_05555	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KU217_05560	COG4605	iron ion homeostasis
KU217_05565	COG4604	ABC transporter, ATP-binding protein
KU217_05570	COG4607	ABC-type enterochelin transport system periplasmic component
KU217_05575	COG4774	siderophore transport
KU217_05585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KU217_05590	COG1021	2,3-dihydroxybenzoate-AMP ligase
KU217_05595	COG1535	isochorismatase
KU217_05595	COG3433	isochorismatase activity
KU217_05605	COG1132	(ABC) transporter
KU217_05610	COG1132	(ABC) transporter
KU217_05615	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KU217_05625	COG1169	isochorismate synthase
KU217_05640	COG3739	integral membrane protein
KU217_05660	COG0302	gtp cyclohydrolase
KU217_05670	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KU217_05700	COG0308	aminopeptidase N
KU217_05705	COG0512	Glutamine amidotransferase of anthranilate synthase
KU217_05720	COG0174	glutamine synthetase
KU217_05730	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KU217_05765	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KU217_05770	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KU217_05775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KU217_05795	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KU217_05800	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KU217_05805	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KU217_05820	COG1960	acyl-CoA dehydrogenase activity
KU217_05825	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KU217_05830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KU217_05840	COG2223	nitrite transmembrane transporter activity
KU217_05850	COG0024	Methionine aminopeptidase
KU217_05855	COG0052	Belongs to the universal ribosomal protein uS2 family
KU217_05870	COG2207	Transcriptional regulator
KU217_05895	COG2951	lytic endotransglycosylase activity
KU217_05900	COG0772	Belongs to the SEDS family
KU217_05915	COG0842	Transport permease protein
KU217_05920	COG1131	(ABC) transporter
KU217_05960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU217_05975	COG4215	(ABC) transporter
KU217_05980	COG4160	amino acid transport
KU217_05985	COG4598	ABC transporter
KU217_05995	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KU217_06000	COG0826	peptidase U32
KU217_06005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU217_06020	COG1720	tRNA m6t6A37 methyltransferase activity
KU217_06030	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KU217_06045	COG0642	Histidine kinase
KU217_06055	COG0494	nUDIX hydrolase
KU217_06065	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KU217_06070	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KU217_06075	COG3139	Protein of unknown function (DUF1315)
KU217_06080	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KU217_06085	COG1301	dicarboxylic acid transport
KU217_06090	COG1960	acyl-CoA dehydrogenase activity
KU217_06095	COG2819	hydrolase of the alpha beta superfamily
KU217_06105	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KU217_06115	COG2195	Cleaves the N-terminal amino acid of tripeptides
KU217_06120	COG1234	tRNA 3'-trailer cleavage
KU217_06150	COG2363	Small membrane protein
KU217_06170	COG0513	Belongs to the DEAD box helicase family
KU217_06180	COG0778	Nitroreductase
KU217_06210	COG1286	toxin biosynthetic process
KU217_06235	COG4783	chaperone-mediated protein folding
KU217_06240	COG1610	YqeY-like protein
KU217_06295	COG2831	hemolysin activation secretion protein
KU217_06410	COG3111	PFAM Bacterial OB fold (BOF) protein
KU217_06435	COG3243	poly(R)-hydroxyalkanoic acid synthase
KU217_06440	COG0786	glutamate:sodium symporter activity
KU217_06450	COG2186	Transcriptional regulator
KU217_06500	COG0477	Major facilitator Superfamily
KU217_06525	COG2985	domain, Protein
KU217_06540	COG2995	paraquat-inducible protein a
KU217_06545	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KU217_06545	COG3008	intermembrane lipid transfer
KU217_06555	COG2351	hydroxyisourate hydrolase activity
KU217_06595	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KU217_06605	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KU217_06610	COG0642	Histidine kinase
KU217_06615	COG0745	RESPONSE REGULATOR receiver
KU217_06635	COG1794	racemase activity, acting on amino acids and derivatives
KU217_06665	COG1301	dicarboxylic acid transport
KU217_06675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KU217_06680	COG2011	ABC-type metal ion transport system permease component
KU217_06685	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KU217_06690	COG1464	Belongs to the NlpA lipoprotein family
KU217_06695	COG0151	Belongs to the GarS family
KU217_06700	COG0138	bifunctional purine biosynthesis protein purh
KU217_06705	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KU217_06735	COG2308	Evidence 4 Homologs of previously reported genes of
KU217_06745	COG1305	Transglutaminase-like
KU217_06755	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KU217_06760	COG0305	Participates in initiation and elongation during chromosome replication
KU217_06785	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KU217_06795	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KU217_06800	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KU217_06825	COG0726	polysaccharide deacetylase
KU217_06825	COG1649	PFAM Uncharacterised BCR, COG1649
KU217_06830	COG1215	transferase activity, transferring glycosyl groups
KU217_06835	COG3658	cytochrome
KU217_06845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KU217_06860	COG0583	DNA-binding transcription factor activity
KU217_06880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU217_06900	COG1960	acyl-CoA dehydrogenase activity
KU217_06905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KU217_06910	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU217_06935	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KU217_06940	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KU217_06950	COG2205	protein histidine kinase activity
KU217_06955	COG0745	RESPONSE REGULATOR receiver
KU217_06960	COG0174	glutamine synthetase
KU217_06980	COG0729	surface antigen
KU217_07005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KU217_07010	COG2814	Major facilitator Superfamily
KU217_07025	COG0583	DNA-binding transcription factor activity
KU217_07040	COG1187	pseudouridine synthase activity
KU217_07060	COG0802	atpase or kinase
KU217_07065	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KU217_07075	COG1923	regulation of RNA biosynthetic process
KU217_07080	COG0697	spore germination
KU217_07105	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KU217_07110	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KU217_07110	COG0519	Catalyzes the synthesis of GMP from XMP
KU217_07115	COG4302	ethanolamine ammonia-lyase activity
KU217_07120	COG4303	Ethanolamine ammonia lyase large subunit
KU217_07125	COG0531	amino acid
KU217_07145	COG1454	alcohol dehydrogenase
KU217_07150	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KU217_07175	COG0308	aminopeptidase N
KU217_07205	COG4221	oxidoreductase activity
KU217_07215	COG1605	Chorismate mutase
KU217_07230	COG1309	transcriptional regulator
KU217_07240	COG0668	transmembrane transport
KU217_07270	COG4773	Receptor
KU217_07290	COG0488	(ABC) transporter
KU217_07295	COG0589	response to stress
KU217_07320	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KU217_07330	COG3135	benzoate transporter
KU217_07335	COG1522	sequence-specific DNA binding
KU217_07345	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KU217_07350	COG0583	DNA-binding transcription factor activity
KU217_07360	COG0183	Belongs to the thiolase family
KU217_07370	COG2030	dehydratase
KU217_07375	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KU217_07390	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KU217_07400	COG0824	Thioesterase
KU217_07405	COG1454	alcohol dehydrogenase
KU217_07415	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KU217_07445	COG0069	glutamate synthase activity
KU217_07465	COG2814	Major facilitator Superfamily
KU217_07480	COG0511	ligase activity, forming carbon-carbon bonds
KU217_07500	COG1116	anion transmembrane transporter activity
KU217_07500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KU217_07505	COG0745	RESPONSE REGULATOR receiver
KU217_07515	COG2146	nitrite reductase [NAD(P)H] activity
KU217_07515	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU217_07520	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU217_07525	COG0243	molybdopterin cofactor binding
KU217_07535	COG0243	molybdopterin cofactor binding
KU217_07540	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KU217_07555	COG0521	Mo-molybdopterin cofactor biosynthetic process
KU217_07555	COG0315	cyclic pyranopterin monophosphate synthase activity
KU217_07570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU217_07575	COG0697	spore germination
KU217_07595	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KU217_07600	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KU217_07655	COG2204	response regulator
KU217_07660	COG3852	Histidine kinase
KU217_07685	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KU217_07690	COG0575	Belongs to the CDS family
KU217_07725	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KU217_07740	COG2137	regulation of response to DNA damage stimulus
KU217_07750	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KU217_07755	COG1011	Hydrolase
KU217_07780	COG1522	sequence-specific DNA binding
KU217_07790	COG1113	amino acid transport
KU217_07805	COG0659	secondary active sulfate transmembrane transporter activity
KU217_07810	COG2135	peptidase activity
KU217_07825	COG5001	Diguanylate cyclase
KU217_07825	COG3300	MHYT domain
KU217_07845	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KU217_07845	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KU217_07845	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KU217_07850	COG1105	Belongs to the carbohydrate kinase PfkB family
KU217_07855	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KU217_07855	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KU217_07885	COG0024	Methionine aminopeptidase
KU217_07890	COG0583	DNA-binding transcription factor activity
KU217_07900	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KU217_07905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KU217_07910	COG0516	GMP reductase activity
KU217_07910	COG0517	IMP dehydrogenase activity
KU217_07935	COG0552	protein localization to endoplasmic reticulum
KU217_07945	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
KU217_07955	COG4890	Cyd operon protein YbgT
KU217_07960	COG1294	oxidase, subunit
KU217_07975	COG1585	Membrane protein implicated in regulation of membrane protease activity
KU217_07985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KU217_07990	COG4774	siderophore transport
KU217_08005	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KU217_08010	COG0569	domain protein
KU217_08015	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KU217_08045	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KU217_08050	COG0542	response to heat
KU217_08075	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU217_08075	COG1902	pentaerythritol trinitrate reductase activity
KU217_08120	COG2323	membrane
KU217_08125	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KU217_08135	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KU217_08140	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KU217_08145	COG0183	Belongs to the thiolase family
KU217_08150	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KU217_08155	COG0596	Alpha beta hydrolase
KU217_08160	COG2271	Major facilitator Superfamily
KU217_08165	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KU217_08170	COG3485	protocatechuate 3,4-dioxygenase
KU217_08175	COG3485	protocatechuate 3,4-dioxygenase
KU217_08180	COG0710	3-dehydroquinate dehydratase activity
KU217_08185	COG3420	alginic acid biosynthetic process
KU217_08190	COG3659	wide pore channel activity
KU217_08195	COG4993	Dehydrogenase
KU217_08205	COG2391	methyltransferase activity
KU217_08220	COG1414	Transcriptional regulator
KU217_08225	COG0583	DNA-binding transcription factor activity
KU217_08230	COG1960	acyl-CoA dehydrogenase activity
KU217_08255	COG2814	Major facilitator Superfamily
KU217_08265	COG0154	amidase activity
KU217_08285	COG4638	Rieske (2fe-2S)
KU217_08295	COG1028	Short-chain dehydrogenase reductase Sdr
KU217_08305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU217_08315	COG3733	amine oxidase
KU217_08325	COG1012	belongs to the aldehyde dehydrogenase family
KU217_08335	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KU217_08340	COG0183	Belongs to the thiolase family
KU217_08345	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KU217_08350	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KU217_08360	COG4829	muconolactone delta-isomerase
KU217_08365	COG4948	Mandelate Racemase Muconate Lactonizing
KU217_08370	COG0583	DNA-binding transcription factor activity
KU217_08380	COG2186	Transcriptional regulator
KU217_08400	COG1012	belongs to the aldehyde dehydrogenase family
KU217_08415	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU217_08415	COG1902	pentaerythritol trinitrate reductase activity
KU217_08425	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KU217_08460	COG1309	transcriptional regulator
KU217_08465	COG0583	DNA-binding transcription factor activity
KU217_08470	COG1028	Short-chain dehydrogenase reductase Sdr
KU217_08475	COG1028	Short-chain dehydrogenase reductase Sdr
KU217_08480	COG1028	Short-chain dehydrogenase reductase Sdr
KU217_08490	COG1960	acyl-CoA dehydrogenase activity
KU217_08500	COG0318	PFAM AMP-dependent synthetase and ligase
KU217_08520	COG4191	Histidine kinase
KU217_08555	COG2188	Transcriptional regulator
KU217_08570	COG0583	DNA-binding transcription factor activity
KU217_08600	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KU217_08610	COG1566	PFAM secretion protein HlyD family protein
KU217_08625	COG1012	belongs to the aldehyde dehydrogenase family
KU217_08630	COG0129	dihydroxy-acid dehydratase activity
KU217_08640	COG0583	DNA-binding transcription factor activity
KU217_08645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KU217_08655	COG2084	Dehydrogenase
KU217_08660	COG2207	Transcriptional regulator
KU217_08665	COG1064	alcohol dehydrogenase
KU217_08675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KU217_08680	COG1120	ATPase activity
KU217_08715	COG1309	transcriptional regulator
KU217_08725	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KU217_08775	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KU217_08820	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
KU217_08835	COG1028	Short-chain dehydrogenase reductase Sdr
KU217_08850	COG2207	Transcriptional regulator
KU217_08860	COG2205	protein histidine kinase activity
KU217_08865	COG0745	RESPONSE REGULATOR receiver
KU217_08870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU217_08875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KU217_08900	COG3539	Fimbrial protein
KU217_08925	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KU217_08935	COG0753	catalase activity
KU217_08950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KU217_09010	COG3433	isochorismatase activity
KU217_09010	COG1535	isochorismatase
KU217_09015	COG1028	Short-chain dehydrogenase reductase Sdr
KU217_09020	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KU217_09025	COG4149	molybdate abc transporter
KU217_09030	COG0725	ABC transporter, periplasmic molybdate-binding protein
KU217_09040	COG4638	Rieske (2fe-2S)
KU217_09045	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KU217_09050	COG0543	2 iron, 2 sulfur cluster binding
KU217_09050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU217_09065	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU217_09075	COG1028	Short-chain dehydrogenase reductase Sdr
KU217_09090	COG2207	Transcriptional regulator
KU217_09095	COG1028	Short-chain dehydrogenase reductase Sdr
KU217_09100	COG2610	gluconate transmembrane transporter activity
KU217_09110	COG1309	transcriptional regulator
KU217_09130	COG0583	DNA-binding transcription factor activity
KU217_09145	COG2031	fatty acid transporter
KU217_09150	COG0183	Belongs to the thiolase family
KU217_09155	COG0583	DNA-binding transcription factor activity
KU217_09160	COG0583	DNA-binding transcription factor activity
KU217_09175	COG1027	Aspartate ammonia-lyase
KU217_09185	COG0477	Major facilitator Superfamily
KU217_09205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU217_09210	COG4521	taurine ABC transporter
KU217_09225	COG2188	Transcriptional regulator
KU217_09235	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KU217_09240	COG1733	regulation of RNA biosynthetic process
KU217_09245	COG2207	Transcriptional regulator
KU217_09245	COG3708	Transcriptional regulator
KU217_09260	COG0730	response to heat
KU217_09270	COG3453	Protein conserved in bacteria
KU217_09270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KU217_09280	COG3781	membrane
KU217_09285	COG1063	alcohol dehydrogenase
KU217_09295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KU217_09300	COG0508	dehydrogenase complex catalyzes the overall conversion of
KU217_09305	COG0022	dehydrogenase e1 component
KU217_09310	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KU217_09315	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KU217_09330	COG3706	GGDEF domain
KU217_09345	COG0133	tryptophan synthase activity
KU217_09355	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KU217_09390	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KU217_09415	COG2226	methyltransferase
KU217_09470	COG0842	Transport permease protein
KU217_09475	COG0842	Transport permease protein
KU217_09480	COG1131	(ABC) transporter
KU217_09495	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KU217_09500	COG4773	Receptor
KU217_09520	COG0730	response to heat
KU217_09525	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KU217_09540	COG0406	alpha-ribazole phosphatase activity
KU217_09560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KU217_09590	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KU217_09600	COG4264	IucA IucC family
KU217_09605	COG4264	IucA IucC family
KU217_09610	COG2814	Major facilitator Superfamily
KU217_09625	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KU217_09640	COG1960	acyl-CoA dehydrogenase activity
KU217_09645	COG1960	acyl-CoA dehydrogenase activity
KU217_09650	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KU217_09655	COG2207	Transcriptional regulator
KU217_09660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KU217_09665	COG0776	regulation of translation
KU217_09690	COG0822	iron-sulfur transferase activity
KU217_09695	COG0316	Belongs to the HesB IscA family
KU217_09725	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KU217_09745	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KU217_09750	COG0702	epimerase
KU217_09785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KU217_09795	COG0339	signal peptide processing
KU217_09840	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KU217_09845	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KU217_09875	COG0776	regulation of translation
KU217_09940	COG0084	hydrolase, TatD family'
KU217_09960	COG1663	tetraacyldisaccharide 4'-kinase activity
KU217_09965	COG1132	(ABC) transporter
KU217_09975	COG0811	peptide transport
KU217_09980	COG1475	DNA binding
KU217_09985	COG1192	Involved in chromosome partitioning
KU217_09995	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KU217_10010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KU217_10015	COG0191	fructose-bisphosphate aldolase activity
KU217_10035	COG0424	maF-like protein
KU217_10040	COG2850	peptidyl-arginine hydroxylation
KU217_10050	COG0640	Transcriptional regulator
KU217_10060	COG3619	membrane
KU217_10065	COG3122	Protein conserved in bacteria
KU217_10070	COG1132	(ABC) transporter
KU217_10090	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KU217_10095	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KU217_10105	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KU217_10105	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KU217_10105	COG0506	proline dehydrogenase activity
KU217_10110	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KU217_10125	COG3698	Phosphodiester glycosidase
KU217_10135	COG2353	YceI-like domain
KU217_10145	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KU217_10190	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KU217_10190	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KU217_10215	COG3539	Fimbrial protein
KU217_10220	COG3121	Chaperone
KU217_10245	COG0697	spore germination
KU217_10255	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KU217_10265	COG0583	DNA-binding transcription factor activity
KU217_10285	COG1309	transcriptional regulator
KU217_10300	COG1522	sequence-specific DNA binding
KU217_10310	COG1126	abc transporter atp-binding protein
KU217_10315	COG0765	amino acid transport
KU217_10320	COG0765	amino acid transport
KU217_10350	COG1464	Belongs to the NlpA lipoprotein family
KU217_10360	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KU217_10365	COG2011	ABC-type metal ion transport system permease component
KU217_10370	COG0012	GTP binding
KU217_10395	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KU217_10435	COG0386	Belongs to the glutathione peroxidase family
KU217_10445	COG0436	Aminotransferase
KU217_10485	COG3634	alkyl hydroperoxide reductase activity
KU217_10500	COG0583	DNA-binding transcription factor activity
KU217_10505	COG0798	PFAM Bile acid sodium symporter
KU217_10510	COG0640	Transcriptional regulator
KU217_10525	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KU217_10535	COG0583	DNA-binding transcription factor activity
KU217_10545	COG1953	Uracil, thiamine, allantoin
KU217_10555	COG2175	clavaminate synthase activity
KU217_10560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU217_10565	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KU217_10570	COG4521	taurine ABC transporter
KU217_10580	COG0477	Major facilitator Superfamily
KU217_10600	COG1271	oxidase subunit
KU217_10605	COG1294	oxidase, subunit
KU217_10615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU217_10645	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KU217_10665	COG3052	prosthetic group binding
KU217_10670	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
KU217_10680	COG0583	DNA-binding transcription factor activity
KU217_10690	COG2814	Major facilitator Superfamily
KU217_10710	COG1346	cytolysis
KU217_10720	COG0583	DNA-binding transcription factor activity
KU217_10725	COG0625	glutathione transferase activity
KU217_10730	COG0625	glutathione transferase activity
KU217_10735	COG0583	DNA-binding transcription factor activity
KU217_10750	COG1045	serine acetyltransferase
KU217_10755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KU217_10765	COG1280	lysine exporter protein (LysE YggA)
KU217_10775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KU217_10780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KU217_10790	COG0765	amino acid transport
KU217_10795	COG0765	amino acid transport
KU217_10815	COG0784	Response regulator, receiver
KU217_10815	COG2205	protein histidine kinase activity
KU217_10835	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KU217_10855	COG1028	Short-chain dehydrogenase reductase Sdr
KU217_10905	COG0583	DNA-binding transcription factor activity
KU217_10925	COG0318	PFAM AMP-dependent synthetase and ligase
KU217_10930	COG1309	transcriptional regulator
KU217_10935	COG1960	acyl-CoA dehydrogenase activity
KU217_10940	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KU217_10945	COG1024	Enoyl-CoA hydratase
KU217_10950	COG4770	biotin carboxylase activity
KU217_10960	COG0583	DNA-binding transcription factor activity
KU217_10975	COG1960	acyl-CoA dehydrogenase activity
KU217_10985	COG2814	Major facilitator Superfamily
KU217_10995	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KU217_11000	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KU217_11005	COG2814	Major facilitator Superfamily
KU217_11010	COG1960	acyl-CoA dehydrogenase activity
KU217_11015	COG1024	Enoyl-CoA hydratase
KU217_11020	COG1028	Short-chain dehydrogenase reductase Sdr
KU217_11025	COG1250	3-hydroxyacyl-CoA dehydrogenase
KU217_11030	COG0183	Belongs to the thiolase family
KU217_11040	COG2814	Major facilitator Superfamily
KU217_11050	COG1024	Enoyl-CoA hydratase
KU217_11065	COG1960	acyl-CoA dehydrogenase activity
KU217_11070	COG2814	Major facilitator Superfamily
KU217_11075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KU217_11080	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KU217_11095	COG3842	ATPase activity
KU217_11100	COG1840	ABC-type Fe3 transport system, periplasmic component
KU217_11110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU217_11115	COG1414	Transcriptional regulator
KU217_11130	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KU217_11135	COG1012	belongs to the aldehyde dehydrogenase family
KU217_11145	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KU217_11155	COG1012	belongs to the aldehyde dehydrogenase family
KU217_11160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KU217_11165	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU217_11170	COG2267	carboxylic ester hydrolase activity
KU217_11190	COG3038	cytochrome b561
KU217_11195	COG0753	catalase activity
KU217_11200	COG2271	Major facilitator Superfamily
KU217_11205	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KU217_11210	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KU217_11225	COG2207	Transcriptional regulator
KU217_11245	COG2050	protein possibly involved in aromatic compounds catabolism
KU217_11255	COG3327	negative regulation of DNA-templated transcription, initiation
KU217_11260	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
KU217_11265	COG0183	Belongs to the thiolase family
KU217_11270	COG1250	3-hydroxyacyl-CoA dehydrogenase
KU217_11275	COG1024	Enoyl-CoA hydratase
KU217_11280	COG1024	Enoyl-CoA hydratase
KU217_11285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU217_11290	COG2151	metal-sulfur cluster biosynthetic enzyme
KU217_11295	COG3396	Phenylacetate-CoA oxygenase
KU217_11300	COG3460	Phenylacetate-CoA oxygenase
KU217_11305	COG3396	Phenylacetate-CoA oxygenase
KU217_11310	COG1012	belongs to the aldehyde dehydrogenase family
KU217_11310	COG2030	dehydratase
KU217_11315	COG1760	l-serine dehydratase
KU217_11320	COG0531	amino acid
KU217_11325	COG1012	belongs to the aldehyde dehydrogenase family
KU217_11370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU217_11380	COG0789	Transcriptional regulator
KU217_11390	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KU217_11405	COG2807	transmembrane transport
KU217_11410	COG0590	tRNA wobble adenosine to inosine editing
KU217_11525	COG1116	anion transmembrane transporter activity
KU217_11530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KU217_11540	COG0864	Transcriptional regulator
KU217_11550	COG1733	regulation of RNA biosynthetic process
KU217_11555	COG2249	NAD(P)H dehydrogenase (quinone) activity
KU217_11560	COG0439	Biotin carboxylase
KU217_11575	COG1063	alcohol dehydrogenase
KU217_11585	COG1309	transcriptional regulator
KU217_11600	COG3210	domain, Protein
KU217_11605	COG2831	hemolysin activation secretion protein
KU217_11610	COG0038	chloride channel
KU217_11615	COG4770	biotin carboxylase activity
KU217_11635	COG1914	H( )-stimulated, divalent metal cation uptake system
KU217_11640	COG0583	DNA-binding transcription factor activity
KU217_11705	COG1250	3-hydroxyacyl-CoA dehydrogenase
KU217_11725	COG2814	Major facilitator Superfamily
KU217_11735	COG1560	Kdo2-lipid A biosynthetic process
KU217_11745	COG5006	permease, DMT superfamily
KU217_11750	COG1522	sequence-specific DNA binding
KU217_11765	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KU217_11775	COG4122	O-methyltransferase activity
KU217_11805	COG1538	Outer membrane efflux protein
KU217_11810	COG1137	ATPase activity
KU217_11815	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KU217_11825	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KU217_11830	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KU217_11830	COG0517	IMP dehydrogenase activity
KU217_11865	COG2814	Major facilitator Superfamily
KU217_11900	COG1278	Cold shock
KU217_11905	COG1280	lysine exporter protein (LysE YggA)
KU217_11935	COG1570	exodeoxyribonuclease VII activity
KU217_12015	COG2871	sodium ion transport
KU217_12025	COG0583	DNA-binding transcription factor activity
KU217_12030	COG4638	Rieske (2fe-2S)
KU217_12035	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KU217_12040	COG0543	2 iron, 2 sulfur cluster binding
KU217_12040	COG0633	Ferredoxin
KU217_12045	COG1028	Short-chain dehydrogenase reductase Sdr
KU217_12050	COG3135	benzoate transporter
KU217_12055	COG2814	Major facilitator Superfamily
KU217_12070	COG1643	Atp-dependent helicase
KU217_12075	COG0450	alkyl hydroperoxide reductase
KU217_12085	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KU217_12095	COG3634	alkyl hydroperoxide reductase activity
KU217_12115	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KU217_12140	COG0625	glutathione transferase activity
KU217_12150	COG2885	chlorophyll binding
KU217_12185	COG0542	response to heat
KU217_12200	COG1765	OsmC-like protein
KU217_12215	COG0667	Aldo Keto reductase
KU217_12230	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KU217_12240	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KU217_12250	COG0527	aspartate kinase activity
KU217_12260	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KU217_12270	COG3038	cytochrome b561
KU217_12275	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KU217_12280	COG2252	PERMEase
KU217_12290	COG2072	flavoprotein involved in K transport
KU217_12305	COG1741	Belongs to the pirin family
KU217_12310	COG1309	transcriptional regulator
KU217_12320	COG0300	oxidoreductase activity
KU217_12325	COG2072	flavoprotein involved in K transport
KU217_12330	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KU217_12335	COG2207	Transcriptional regulator
KU217_12375	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KU217_12390	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU217_12405	COG2814	Major facilitator Superfamily
KU217_12410	COG1024	Enoyl-CoA hydratase
KU217_12415	COG1012	belongs to the aldehyde dehydrogenase family
KU217_12425	COG1960	acyl-CoA dehydrogenase activity
KU217_12450	COG2186	Transcriptional regulator
KU217_12455	COG1012	belongs to the aldehyde dehydrogenase family
KU217_12465	COG4948	Mandelate Racemase Muconate Lactonizing
KU217_12470	COG2271	Major facilitator Superfamily
KU217_12475	COG2721	sulfolactate sulfo-lyase activity
KU217_12480	COG0697	spore germination
KU217_12515	COG1113	amino acid transport
KU217_12535	COG1012	belongs to the aldehyde dehydrogenase family
KU217_12555	COG0531	amino acid
KU217_12565	COG1113	amino acid transport
KU217_12595	COG3209	COG3209 Rhs family protein
KU217_12620	COG4269	membrane
KU217_12635	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU217_12635	COG1902	pentaerythritol trinitrate reductase activity
KU217_12650	COG3706	GGDEF domain
KU217_12650	COG4251	negative regulation of phosphorylation
KU217_12650	COG5001	Diguanylate cyclase
KU217_12650	COG2203	Gaf domain
KU217_12660	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KU217_12680	COG4172	Belongs to the ABC transporter superfamily
KU217_12685	COG4239	(ABC) transporter, permease
KU217_12690	COG4174	ABC transporter (Permease)
KU217_12700	COG1388	LysM domain
KU217_12700	COG0741	lytic transglycosylase activity
KU217_12700	COG1388	LysM domain
KU217_12700	COG0741	lytic transglycosylase activity
KU217_12705	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KU217_12745	COG0583	DNA-binding transcription factor activity
KU217_12750	COG1279	arginine transmembrane transporter activity
KU217_12770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU217_12775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU217_12780	COG0006	proline dipeptidase activity
KU217_12820	COG2194	sulfuric ester hydrolase activity
KU217_12865	COG0739	heme binding
KU217_13170	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KU217_13195	COG3384	dioxygenase
KU217_13205	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KU217_13210	COG2878	Part of a membrane complex involved in electron transport
KU217_13215	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KU217_13240	COG0768	penicillin binding
KU217_13245	COG0742	ribosomal rna small subunit methyltransferase
KU217_13260	COG0830	nickel cation binding
KU217_13305	COG1253	flavin adenine dinucleotide binding
KU217_13310	COG2851	Citrate transporter
KU217_13360	COG1773	rubredoxin
KU217_13365	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU217_13375	COG0583	DNA-binding transcription factor activity
KU217_13400	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KU217_13405	COG4181	ATPase activity
KU217_13450	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KU217_13470	COG0306	phosphate transporter
KU217_13480	COG3958	Transketolase
KU217_13485	COG3959	Transketolase, thiamine diphosphate binding domain
KU217_13490	COG2271	Major facilitator Superfamily
KU217_13495	COG1028	Short-chain dehydrogenase reductase Sdr
KU217_13500	COG0583	DNA-binding transcription factor activity
KU217_13515	COG2223	nitrite transmembrane transporter activity
KU217_13520	COG2207	Transcriptional regulator
KU217_13525	COG2066	Belongs to the glutaminase family
KU217_13530	COG0242	peptide deformylase activity
KU217_13535	COG0477	Major facilitator Superfamily
KU217_13545	COG0028	Belongs to the TPP enzyme family
KU217_13560	COG1028	Short-chain dehydrogenase reductase Sdr
KU217_13565	COG2267	carboxylic ester hydrolase activity
KU217_13575	COG2271	Major facilitator Superfamily
KU217_13580	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU217_13590	COG1028	Short-chain dehydrogenase reductase Sdr
KU217_13610	COG1414	Transcriptional regulator
KU217_13625	COG1024	Enoyl-CoA hydratase
KU217_13635	COG1215	transferase activity, transferring glycosyl groups
KU217_13640	COG0726	polysaccharide deacetylase
KU217_13640	COG1649	PFAM Uncharacterised BCR, COG1649
KU217_13650	COG4681	YaeQ
KU217_13660	COG0523	cobalamin synthesis protein
KU217_13670	COG1607	acyl-coa hydrolase
KU217_13680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU217_13685	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU217_13690	COG1309	transcriptional regulator
KU217_13715	COG2040	homocysteine
KU217_13720	COG0531	amino acid
KU217_13775	COG1595	DNA-templated transcription, initiation
KU217_13785	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU217_13790	COG0477	Major facilitator Superfamily
KU217_13800	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
KU217_13825	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KU217_13865	COG1061	Type III restriction enzyme res subunit
KU217_13875	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KU217_13880	COG1192	Involved in chromosome partitioning
KU217_13975	COG0592	DNA-directed DNA polymerase activity
KU217_14015	COG2026	Addiction module toxin, RelE StbE family
KU217_14165	COG3755	Protein conserved in bacteria
KU217_14210	COG1484	DNA-dependent DNA replication
KU217_14325	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KU217_14360	COG0405	Gamma-glutamyltransferase
KU217_14365	COG2814	Major facilitator Superfamily
KU217_14375	COG2050	protein possibly involved in aromatic compounds catabolism
KU217_14390	COG1090	epimerase
KU217_14410	COG0420	3'-5' exonuclease activity
KU217_14435	COG0735	belongs to the Fur family
KU217_14440	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KU217_14460	COG0121	glutamine amidotransferase
KU217_14475	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KU217_14485	COG0210	DNA helicase
KU217_14490	COG2885	chlorophyll binding
KU217_14495	COG0204	Acyl-transferase
KU217_14510	COG2894	cell division
KU217_14525	COG1280	lysine exporter protein (LysE YggA)
KU217_14530	COG1674	ftsk spoiiie
KU217_14530	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KU217_14535	COG0492	ferredoxin-NADP+ reductase activity
KU217_14540	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KU217_14550	COG0456	acetyltransferase
KU217_14595	COG1981	membrane
KU217_14610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KU217_14610	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KU217_14630	COG1012	belongs to the aldehyde dehydrogenase family
KU217_14640	COG0657	acetylesterase activity
KU217_14650	COG0473	3-isopropylmalate dehydrogenase activity
KU217_14655	COG0583	DNA-binding transcription factor activity
KU217_14675	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KU217_14700	COG0564	pseudouridine synthase activity
KU217_14710	COG0358	DNA primase activity
KU217_14725	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KU217_14755	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KU217_14785	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KU217_14795	COG0352	thiamine-phosphate diphosphorylase activity
KU217_14795	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KU217_14795	COG0351	phosphomethylpyrimidine kinase
KU217_14800	COG1652	LysM domain
KU217_14825	COG1399	metal-binding, possibly nucleic acid-binding protein
KU217_14830	COG3101	peptidyl-lysine hydroxylation
KU217_14835	COG0009	L-threonylcarbamoyladenylate synthase
KU217_14840	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KU217_14845	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KU217_14860	COG4106	trans-aconitate 2-methyltransferase activity
KU217_14875	COG0596	Alpha beta hydrolase
KU217_14875	COG2226	methyltransferase
KU217_14875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KU217_14880	COG1877	trehalose-phosphatase activity
KU217_14885	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
KU217_14890	COG2223	nitrite transmembrane transporter activity
KU217_14910	COG1196	nuclear chromosome segregation
KU217_14920	COG0730	response to heat
KU217_14935	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KU217_14945	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KU217_14995	COG0489	protein tyrosine kinase activity
KU217_15005	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KU217_15005	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KU217_15035	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KU217_15040	COG2081	HI0933 family
KU217_15050	COG0668	transmembrane transport
KU217_15070	COG0583	DNA-binding transcription factor activity
KU217_15095	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KU217_15100	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KU217_15130	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KU217_15170	COG0745	RESPONSE REGULATOR receiver
KU217_15190	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KU217_15195	COG0697	spore germination
KU217_15230	COG0477	Major facilitator Superfamily
KU217_15240	COG1028	Short-chain dehydrogenase reductase Sdr
KU217_15285	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU217_15320	COG0583	DNA-binding transcription factor activity
KU217_15335	COG0583	DNA-binding transcription factor activity
KU217_15340	COG1053	succinate dehydrogenase
KU217_15350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KU217_15355	COG2814	Major facilitator Superfamily
KU217_15360	COG1960	acyl-CoA dehydrogenase activity
KU217_15365	COG0583	DNA-binding transcription factor activity
KU217_15370	COG1063	alcohol dehydrogenase
KU217_15385	COG0582	viral genome integration into host DNA
KU217_15415	COG1122	ATPase activity
KU217_15605	COG4695	Portal protein
KU217_15615	COG1724	mRNA binding
KU217_15620	COG1598	PFAM Uncharacterised protein family UPF0150
KU217_15650	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KU217_15655	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KU217_15660	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KU217_15680	COG2132	Multicopper oxidase
KU217_15690	COG0561	phosphatase activity
KU217_15695	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KU217_15705	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
KU217_15720	COG1214	PFAM Peptidase M22, glycoprotease
KU217_15770	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KU217_15780	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KU217_15785	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KU217_15790	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KU217_15850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KU217_15860	COG1846	Transcriptional regulator
KU217_15865	COG1764	response to oxidative stress
KU217_15905	COG0037	tRNA processing
KU217_15915	COG0248	Ppx GppA phosphatase
KU217_15945	COG0072	phenylalanine-tRNA ligase activity
KU217_15985	COG1238	metal cluster binding
KU217_15990	COG0625	glutathione transferase activity
KU217_16005	COG0318	PFAM AMP-dependent synthetase and ligase
KU217_16010	COG3028	Belongs to the UPF0307 family
KU217_16035	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KU217_16040	COG0617	tRNA 3'-terminal CCA addition
KU217_16045	COG1555	photosystem II stabilization
KU217_16050	COG3956	TIGRFAM MazG family protein
KU217_16060	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KU217_16080	COG2205	protein histidine kinase activity
KU217_16080	COG0784	Response regulator, receiver
KU217_16080	COG5002	protein histidine kinase activity
KU217_16085	COG1024	Enoyl-CoA hydratase
KU217_16090	COG2084	Dehydrogenase
KU217_16095	COG3622	Belongs to the hyi family
KU217_16125	COG0697	spore germination
KU217_16135	COG2814	Major facilitator Superfamily
KU217_16140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KU217_16150	COG0583	DNA-binding transcription factor activity
KU217_16160	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KU217_16170	COG0084	hydrolase, TatD family'
KU217_16185	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KU217_16225	COG0440	acetolactate synthase activity
KU217_16230	COG0028	Belongs to the TPP enzyme family
KU217_16255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU217_16260	COG1136	(ABC) transporter
KU217_16260	COG0577	efflux transmembrane transporter activity
KU217_16265	COG1538	Outer membrane efflux protein
KU217_16280	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KU217_16285	COG1162	GTPase activity
KU217_16295	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KU217_16335	COG1426	Protein conserved in bacteria
KU217_16370	COG0793	Belongs to the peptidase S41A family
KU217_16385	COG2267	carboxylic ester hydrolase activity
KU217_16395	COG1012	belongs to the aldehyde dehydrogenase family
KU217_16400	COG3265	gluconokinase activity
KU217_16410	COG0800	Aldolase
KU217_16420	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KU217_16425	COG0857	belongs to the CobB CobQ family
KU217_16425	COG0280	phosphate acetyltransferase
KU217_16430	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KU217_16430	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KU217_16450	COG0740	serine-type endopeptidase activity
KU217_16460	COG4774	siderophore transport
KU217_16470	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KU217_16480	COG2813	Specifically methylates the guanine in position
KU217_16480	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KU217_16580	COG0788	formyltetrahydrofolate deformylase activity
KU217_16605	COG4651	solute:proton antiporter activity
KU217_16605	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KU217_16625	COG0724	RNA recognition motif
KU217_16630	COG0210	DNA helicase
KU217_16655	COG1733	regulation of RNA biosynthetic process
KU217_16665	COG2900	Belongs to the SlyX family
KU217_16670	COG0488	(ABC) transporter
KU217_16675	COG1280	lysine exporter protein (LysE YggA)
KU217_16680	COG1560	Kdo2-lipid A biosynthetic process
KU217_16690	COG1301	dicarboxylic acid transport
KU217_16745	COG0473	3-isopropylmalate dehydrogenase activity
KU217_16810	COG0583	DNA-binding transcription factor activity
KU217_16820	COG0625	glutathione transferase activity
KU217_16825	COG2378	regulation of single-species biofilm formation
KU217_16830	COG0546	phosphoglycolate phosphatase activity
KU217_16840	COG1530	ribonuclease E activity
KU217_16845	COG0318	PFAM AMP-dependent synthetase and ligase
KU217_16860	COG0583	DNA-binding transcription factor activity
KU217_16865	COG4221	oxidoreductase activity
KU217_16870	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KU217_16880	COG0534	Mate efflux family protein
KU217_16895	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KU217_16920	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
KU217_16920	COG0493	'glutamate synthase
KU217_16930	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KU217_16935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KU217_16950	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KU217_16960	COG0644	oxidoreductase
KU217_16960	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
KU217_16970	COG0425	Belongs to the sulfur carrier protein TusA family
KU217_16975	COG4535	Mg2 and Co2 transporter CorC
KU217_16985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KU217_17005	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KU217_17010	COG0475	glutathione-regulated potassium exporter activity
KU217_17010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KU217_17025	COG0484	heat shock protein binding
KU217_17030	COG0789	Transcriptional regulator
KU217_17035	COG0598	Magnesium transport protein CorA
KU217_17050	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KU217_17055	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KU217_17060	COG1074	ATP-dependent DNA helicase activity
KU217_17065	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KU217_17085	COG2226	methyltransferase
KU217_17105	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KU217_17120	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KU217_17120	COG2111	Na H antiporter
KU217_17125	COG1006	Multisubunit Na H antiporter MnhC subunit
KU217_17130	COG0651	ATP synthesis coupled electron transport
KU217_17135	COG1863	multisubunit Na H antiporter MnhE subunit
KU217_17140	COG2212	antiporter activity
KU217_17145	COG1320	monovalent cation:proton antiporter activity
KU217_17160	COG0195	Participates in both transcription termination and antitermination
KU217_17210	COG0237	dephospho-CoA kinase activity
KU217_17220	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KU217_17235	COG0497	DNA recombination
KU217_17245	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KU217_17275	COG2169	Transcriptional regulator
KU217_17275	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KU217_17280	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KU217_17335	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KU217_17350	COG0326	Molecular chaperone. Has ATPase activity
KU217_17365	COG2056	Na+-H+ antiporter family
KU217_17370	COG0596	Alpha beta hydrolase
KU217_17465	COG0546	phosphoglycolate phosphatase activity
KU217_17470	COG1716	ATPase activity
KU217_17515	COG0181	hydroxymethylbilane synthase activity
KU217_17525	COG3275	phosphorelay sensor kinase activity
KU217_17545	COG1538	Outer membrane efflux protein
KU217_17550	COG0697	spore germination
KU217_17575	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KU217_17580	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KU217_17585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KU217_17590	COG0772	Belongs to the SEDS family
KU217_17615	COG4974	Belongs to the 'phage' integrase family
KU217_17620	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KU217_17630	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KU217_17640	COG2197	response regulator
KU217_17655	COG0793	Belongs to the peptidase S41A family
KU217_17660	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KU217_17665	COG0795	lipopolysaccharide-transporting ATPase activity
KU217_17705	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KU217_17705	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KU217_17715	COG0004	ammonium transporteR
KU217_17720	COG0347	Belongs to the P(II) protein family
KU217_17730	COG0606	chelatase, subunit chli
KU217_17735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU217_17745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU217_17760	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KU217_17775	COG0318	PFAM AMP-dependent synthetase and ligase
KU217_17785	COG0477	Major facilitator Superfamily
KU217_17790	COG2860	membrane
KU217_17800	COG1253	flavin adenine dinucleotide binding
KU217_17810	COG0477	Major facilitator Superfamily
KU217_17820	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KU217_17855	COG0655	NAD(P)H dehydrogenase (quinone) activity
KU217_17865	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KU217_17900	COG1309	transcriptional regulator
KU217_17935	COG0758	DNA mediated transformation
KU217_17945	COG0697	spore germination
KU217_17950	COG1309	transcriptional regulator
KU217_17965	COG0386	Belongs to the glutathione peroxidase family
KU217_18030	COG1121	(ABC) transporter
KU217_18035	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KU217_18040	COG1280	lysine exporter protein (LysE YggA)
KU217_18045	COG2837	iron assimilation
KU217_18050	COG0281	malic enzyme
KU217_18095	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KU217_18095	COG0519	Catalyzes the synthesis of GMP from XMP
KU217_18100	COG4399	Belongs to the UPF0754 family
KU217_18105	COG2259	Doxx family
KU217_18110	COG0586	Pfam SNARE associated Golgi protein
KU217_18125	COG1192	Involved in chromosome partitioning
KU217_18135	COG0271	Belongs to the BolA IbaG family
KU217_18155	COG2267	carboxylic ester hydrolase activity
KU217_18175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KU217_18175	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KU217_18175	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KU217_18175	COG3321	synthase
KU217_18180	COG1960	acyl-CoA dehydrogenase activity
KU217_18190	COG2197	response regulator
KU217_18200	COG3916	Acyl-homoserine-lactone synthase
KU217_18205	COG0477	Major facilitator Superfamily
KU217_18210	COG1024	Enoyl-CoA hydratase
KU217_18215	COG1024	Enoyl-CoA hydratase
KU217_18220	COG1960	acyl-CoA dehydrogenase activity
KU217_18225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KU217_18245	COG1113	amino acid transport
KU217_18250	COG1113	amino acid transport
KU217_18255	COG0251	oxidation-reduction process
KU217_18295	COG0564	pseudouridine synthase activity
KU217_18355	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KU217_18370	COG1802	Transcriptional regulator
KU217_18380	COG1448	Aminotransferase
KU217_18385	COG0277	FAD linked oxidase domain protein
KU217_18395	COG2186	Transcriptional regulator
KU217_18405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KU217_18410	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KU217_18425	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KU217_18430	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KU217_18455	COG2244	polysaccharide biosynthetic process
KU217_18460	COG1083	cytidylyl-transferase
KU217_18465	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KU217_18475	COG2089	acid synthase
KU217_18480	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KU217_18485	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KU217_18495	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KU217_18500	COG1596	polysaccharide export
KU217_18525	COG0728	peptidoglycan biosynthetic process
KU217_18530	COG3023	N-Acetylmuramoyl-L-alanine amidase
KU217_18590	COG0546	phosphoglycolate phosphatase activity
KU217_18595	COG1028	Short-chain dehydrogenase reductase Sdr
KU217_18615	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KU217_18620	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KU217_18625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KU217_18630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU217_18635	COG1116	anion transmembrane transporter activity
KU217_18640	COG1309	transcriptional regulator
KU217_18645	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KU217_18655	COG0196	riboflavin kinase activity
KU217_18660	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KU217_18670	COG1047	Peptidyl-prolyl cis-trans
KU217_18710	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KU217_18715	COG0657	acetylesterase activity
KU217_18765	COG2951	lytic endotransglycosylase activity
KU217_18770	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KU217_18785	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KU217_18795	COG0671	phosphoesterase, PA-phosphatase related
KU217_18800	COG0861	Integral membrane protein TerC family
KU217_18810	COG0754	glutathionylspermidine amidase activity
KU217_18820	COG0402	S-adenosylhomocysteine deaminase activity
KU217_18835	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KU217_18840	COG1230	cation diffusion facilitator family transporter
KU217_18855	COG0706	membrane insertase activity
KU217_18925	COG1525	nuclease
KU217_18995	COG1475	DNA binding
KU217_19010	COG3853	Toxic anion resistance protein (TelA)
KU217_19115	COG0484	heat shock protein binding
KU217_19200	COG0741	lytic transglycosylase activity
KU217_19235	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process