locus-tag	class	description
KU251_00010	COG0592	DNA-directed DNA polymerase activity
KU251_00020	COG0187	DNA topoisomerase II activity
KU251_00030	COG0586	Pfam SNARE associated Golgi protein
KU251_00035	COG0488	(ABC) transporter
KU251_00060	COG0596	Alpha beta hydrolase
KU251_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KU251_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KU251_00110	COG0733	neurotransmitter:sodium symporter activity
KU251_00150	COG2233	PERMEase
KU251_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU251_00200	COG2814	Major facilitator Superfamily
KU251_00205	COG0656	L-ascorbic acid biosynthetic process
KU251_00210	COG0583	DNA-binding transcription factor activity
KU251_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU251_00230	COG1064	alcohol dehydrogenase
KU251_00235	COG2818	Glycosylase
KU251_00250	COG1194	a g-specific adenine glycosylase
KU251_00270	COG2983	Belongs to the UPF0260 family
KU251_00275	COG2133	pyrroloquinoline quinone binding
KU251_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KU251_00285	COG2116	formate transmembrane transporter activity
KU251_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU251_00310	COG1335	isochorismatase
KU251_00315	COG0385	Bile acid
KU251_00320	COG0534	Mate efflux family protein
KU251_00325	COG1683	Conserved Protein
KU251_00345	COG0625	glutathione transferase activity
KU251_00355	COG1113	amino acid transport
KU251_00365	COG0523	cobalamin synthesis protein
KU251_00375	COG2188	Transcriptional regulator
KU251_00405	COG0010	Belongs to the arginase family
KU251_00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KU251_00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KU251_00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KU251_00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KU251_00540	COG0534	Mate efflux family protein
KU251_00545	COG0436	Aminotransferase
KU251_00550	COG2733	membrane
KU251_00565	COG2918	glutathione biosynthetic process
KU251_00580	COG1388	LysM domain
KU251_00580	COG0791	NLP P60 protein
KU251_00595	COG3150	esterase
KU251_00605	COG1028	Short-chain dehydrogenase reductase Sdr
KU251_00610	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
KU251_00620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU251_00630	COG2233	PERMEase
KU251_00635	COG2351	hydroxyisourate hydrolase activity
KU251_00670	COG3706	GGDEF domain
KU251_00685	COG1393	Belongs to the ArsC family
KU251_00690	COG0708	Exodeoxyribonuclease III
KU251_00710	COG0189	ligase activity
KU251_00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KU251_00740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KU251_00755	COG4942	peptidase
KU251_00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
KU251_00775	COG2119	membrane
KU251_00780	COG4774	siderophore transport
KU251_00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU251_00785	COG0426	domain, Protein
KU251_00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KU251_00830	COG1902	pentaerythritol trinitrate reductase activity
KU251_00835	COG1519	Transferase
KU251_00840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KU251_00845	COG0668	transmembrane transport
KU251_00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KU251_00860	COG1335	isochorismatase
KU251_00865	COG1522	sequence-specific DNA binding
KU251_00870	COG3328	transposase activity
KU251_00895	COG0784	Response regulator, receiver
KU251_00895	COG2198	Histidine kinase
KU251_00895	COG2205	protein histidine kinase activity
KU251_00900	COG3162	membrane
KU251_00905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KU251_00915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU251_00935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KU251_00940	COG1309	transcriptional regulator
KU251_00965	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KU251_00965	COG0352	thiamine-phosphate diphosphorylase activity
KU251_00965	COG0351	phosphomethylpyrimidine kinase
KU251_00975	COG2814	Major facilitator Superfamily
KU251_00990	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KU251_01000	COG1113	amino acid transport
KU251_01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KU251_01015	COG1012	belongs to the aldehyde dehydrogenase family
KU251_01025	COG1335	isochorismatase
KU251_01055	COG2814	Major facilitator Superfamily
KU251_01060	COG0583	DNA-binding transcription factor activity
KU251_01080	COG0667	Aldo Keto reductase
KU251_01115	COG1733	regulation of RNA biosynthetic process
KU251_01120	COG2249	NAD(P)H dehydrogenase (quinone) activity
KU251_01185	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KU251_01200	COG2329	Antibiotic biosynthesis monooxygenase
KU251_01230	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KU251_01260	COG0427	acetyl-CoA hydrolase
KU251_01285	COG0659	secondary active sulfate transmembrane transporter activity
KU251_01290	COG4221	oxidoreductase activity
KU251_01295	COG2873	o-acetylhomoserine
KU251_01300	COG0488	(ABC) transporter
KU251_01385	COG0833	amino acid
KU251_01430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KU251_01435	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KU251_01450	COG2226	methyltransferase
KU251_01500	COG0067	glutamate synthase
KU251_01500	COG0069	glutamate synthase activity
KU251_01500	COG0070	glutamate synthase
KU251_01505	COG0493	'glutamate synthase
KU251_01515	COG1704	LemA family
KU251_01520	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KU251_01540	COG3307	-O-antigen
KU251_01565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KU251_01580	COG0194	GDP metabolic process
KU251_01630	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KU251_01650	COG5380	lipid catabolic process
KU251_01655	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KU251_01680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KU251_01685	COG0277	FAD linked oxidase domain protein
KU251_01695	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KU251_01700	COG2249	NAD(P)H dehydrogenase (quinone) activity
KU251_01715	COG1289	transmembrane transporter activity
KU251_01725	COG0628	permease
KU251_01730	COG1192	Involved in chromosome partitioning
KU251_01760	COG0833	amino acid
KU251_01765	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KU251_01770	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KU251_01780	COG1012	belongs to the aldehyde dehydrogenase family
KU251_01820	COG0583	DNA-binding transcription factor activity
KU251_01865	COG0517	IMP dehydrogenase activity
KU251_01870	COG1983	PspC domain protein
KU251_01880	COG1960	acyl-CoA dehydrogenase activity
KU251_01895	COG0408	coproporphyrinogen oxidase activity
KU251_01915	COG0513	Belongs to the DEAD box helicase family
KU251_01925	COG1127	ABC transporter
KU251_01930	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KU251_01940	COG2854	intermembrane phospholipid transfer
KU251_01950	COG0598	Magnesium transport protein CorA
KU251_01960	COG0494	nUDIX hydrolase
KU251_01965	COG1040	competence protein
KU251_01970	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KU251_01990	COG1946	Acyl-CoA thioesterase
KU251_01995	COG1301	dicarboxylic acid transport
KU251_02010	COG1959	2 iron, 2 sulfur cluster binding
KU251_02015	COG1017	nitric oxide dioxygenase activity
KU251_02015	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU251_02020	COG0433	COG0433 Predicted ATPase
KU251_02025	COG0626	cystathionine gamma-synthase activity
KU251_02180	COG1960	acyl-CoA dehydrogenase activity
KU251_02185	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KU251_02215	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KU251_02220	COG0339	signal peptide processing
KU251_02225	COG0557	exoribonuclease II activity
KU251_02270	COG0179	Fumarylacetoacetate (FAA) hydrolase
KU251_02275	COG2169	Transcriptional regulator
KU251_02280	COG0697	spore germination
KU251_02285	COG1295	ribonuclease BN
KU251_02320	COG1702	phosphate starvation-inducible protein PhoH
KU251_02330	COG0739	heme binding
KU251_02330	COG0741	lytic transglycosylase activity
KU251_02330	COG1196	nuclear chromosome segregation
KU251_02360	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KU251_02365	COG1183	phosphatidylcholine synthase activity
KU251_02410	COG1960	acyl-CoA dehydrogenase activity
KU251_02415	COG1309	transcriptional regulator
KU251_02430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KU251_02435	COG1960	acyl-CoA dehydrogenase activity
KU251_02455	COG2969	positive regulation of protein catabolic process
KU251_02465	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KU251_02480	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KU251_02485	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KU251_02505	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KU251_02515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KU251_02520	COG1408	metallophosphoesterase
KU251_02530	COG2199	diguanylate cyclase activity
KU251_02590	COG1607	acyl-coa hydrolase
KU251_02620	COG2350	Protein conserved in bacteria
KU251_02630	COG0613	PHP domain protein
KU251_02635	COG3781	membrane
KU251_02645	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KU251_02650	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KU251_02660	COG1862	Preprotein translocase
KU251_02690	COG2205	protein histidine kinase activity
KU251_02695	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KU251_02715	COG0726	polysaccharide deacetylase
KU251_02720	COG0463	Glycosyl transferase, family 2
KU251_02725	COG0438	transferase activity, transferring glycosyl groups
KU251_02790	COG0625	glutathione transferase activity
KU251_02795	COG0583	DNA-binding transcription factor activity
KU251_02800	COG1960	acyl-CoA dehydrogenase activity
KU251_02805	COG1960	acyl-CoA dehydrogenase activity
KU251_02815	COG2205	protein histidine kinase activity
KU251_02820	COG0745	RESPONSE REGULATOR receiver
KU251_02825	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KU251_02845	COG2096	Adenosyltransferase
KU251_02895	COG0285	dihydrofolate synthase activity
KU251_02915	COG0450	alkyl hydroperoxide reductase
KU251_02930	COG0477	Major facilitator Superfamily
KU251_02935	COG1272	protein, Hemolysin III
KU251_02965	COG0183	Belongs to the thiolase family
KU251_02970	COG2207	Transcriptional regulator
KU251_02990	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU251_03010	COG0183	Belongs to the thiolase family
KU251_03020	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KU251_03020	COG2885	chlorophyll binding
KU251_03030	COG1690	Belongs to the RtcB family
KU251_03035	COG0833	amino acid
KU251_03045	COG2233	PERMEase
KU251_03050	COG1217	gtp-binding protein TYPA
KU251_03075	COG2094	Belongs to the DNA glycosylase MPG family
KU251_03080	COG4772	TonB-dependent receptor
KU251_03095	COG1902	pentaerythritol trinitrate reductase activity
KU251_03110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KU251_03115	COG0354	folic acid binding
KU251_03125	COG3189	MarR family transcriptional regulator
KU251_03130	COG2824	Alkylphosphonate utilization operon protein PhnA
KU251_03135	COG3422	double-strand break repair
KU251_03175	COG0840	transmembrane signaling receptor activity
KU251_03195	COG5510	response to toxic substance
KU251_03205	COG2832	Protein of unknown function (DUF454)
KU251_03210	COG1376	ErfK ybiS ycfS ynhG family protein
KU251_03250	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KU251_03260	COG1289	transmembrane transporter activity
KU251_03265	COG2814	Major facilitator Superfamily
KU251_03285	COG1115	amino acid carrier protein
KU251_03290	COG1752	Esterase of the alpha-beta hydrolase superfamily
KU251_03295	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KU251_03300	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
KU251_03335	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KU251_03345	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KU251_03350	COG1077	Cell shape determining protein MreB Mrl
KU251_03355	COG1792	Involved in formation and maintenance of cell shape
KU251_03360	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KU251_03365	COG0424	maF-like protein
KU251_03370	COG1530	ribonuclease E activity
KU251_03380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KU251_03390	COG0560	Phosphoserine phosphatase
KU251_03400	COG2249	NAD(P)H dehydrogenase (quinone) activity
KU251_03425	COG2207	Transcriptional regulator
KU251_03445	COG1113	amino acid transport
KU251_03450	COG2828	Protein conserved in bacteria
KU251_03455	COG0142	geranyltranstransferase activity
KU251_03460	COG2315	Protein conserved in bacteria
KU251_03475	COG1752	Esterase of the alpha-beta hydrolase superfamily
KU251_03495	COG2194	sulfuric ester hydrolase activity
KU251_03500	COG0745	RESPONSE REGULATOR receiver
KU251_03505	COG0642	Histidine kinase
KU251_03515	COG0004	ammonium transporteR
KU251_03520	COG0583	DNA-binding transcription factor activity
KU251_03540	COG0525	valine-tRNA ligase activity
KU251_03550	COG1028	Short-chain dehydrogenase reductase Sdr
KU251_03560	COG0393	Putative heavy-metal-binding
KU251_03565	COG0393	Putative heavy-metal-binding
KU251_03570	COG1538	Outer membrane efflux protein
KU251_03580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU251_03585	COG0671	phosphoesterase, PA-phosphatase related
KU251_03615	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KU251_03630	COG1648	precorrin-2 dehydrogenase activity
KU251_03630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KU251_03635	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KU251_03640	COG1733	regulation of RNA biosynthetic process
KU251_03650	COG0531	amino acid
KU251_03665	COG0321	lipoyl(octanoyl) transferase activity
KU251_03670	COG2921	Belongs to the UPF0250 family
KU251_03710	COG2009	succinate dehydrogenase
KU251_03715	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KU251_03720	COG1053	succinate dehydrogenase
KU251_03725	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KU251_03750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KU251_03770	COG2354	Protein conserved in bacteria
KU251_03775	COG2321	neutral zinc metallopeptidase
KU251_03810	COG2843	Capsule synthesis protein
KU251_03825	COG0589	response to stress
KU251_03845	COG0505	Belongs to the CarA family
KU251_03870	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KU251_03875	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KU251_03925	COG0477	Major facilitator Superfamily
KU251_03930	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KU251_03945	COG1597	lipid kinase activity
KU251_03950	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KU251_03980	COG0584	glycerophosphoryl diester phosphodiesterase
KU251_04000	COG0741	lytic transglycosylase activity
KU251_04020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KU251_04035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KU251_04060	COG0778	Nitroreductase
KU251_04075	COG1929	Belongs to the glycerate kinase type-1 family
KU251_04080	COG0243	molybdopterin cofactor binding
KU251_04085	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KU251_04090	COG3339	Conserved Protein
KU251_04100	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KU251_04115	COG1113	amino acid transport
KU251_04125	COG0019	diaminopimelate decarboxylase activity
KU251_04135	COG1280	lysine exporter protein (LysE YggA)
KU251_04140	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KU251_04170	COG0463	Glycosyl transferase, family 2
KU251_04190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU251_04225	COG4591	ABC-type transport system involved in lipoprotein release permease component
KU251_04230	COG1136	(ABC) transporter
KU251_04235	COG2333	competence protein COMEC
KU251_04235	COG0658	competence protein
KU251_04245	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KU251_04245	COG0616	signal peptide processing
KU251_04250	COG0596	Alpha beta hydrolase
KU251_04255	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KU251_04265	COG0628	permease
KU251_04300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KU251_04320	COG0823	Involved in the tonB-independent uptake of proteins
KU251_04340	COG0824	Thioesterase
KU251_04345	COG1473	amidohydrolase
KU251_04365	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KU251_04365	COG0047	phosphoribosylformylglycinamidine synthase activity
KU251_04370	COG2814	Major facilitator Superfamily
KU251_04380	COG1024	Enoyl-CoA hydratase
KU251_04385	COG1051	belongs to the nudix hydrolase family
KU251_04385	COG1056	cytidyltransferase-related domain
KU251_04395	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KU251_04410	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KU251_04425	COG4625	pathogenesis
KU251_04430	COG0583	DNA-binding transcription factor activity
KU251_04435	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KU251_04440	COG4208	sulfate ABC transporter
KU251_04445	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KU251_04455	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KU251_04460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KU251_04465	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KU251_04485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KU251_04500	COG0681	Belongs to the peptidase S26 family
KU251_04515	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KU251_04525	COG1381	Involved in DNA repair and RecF pathway recombination
KU251_04530	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KU251_04540	COG4221	oxidoreductase activity
KU251_04570	COG0436	Aminotransferase
KU251_04590	COG0556	nucleotide-excision repair
KU251_04645	COG2070	2-Nitropropane dioxygenase
KU251_04675	COG1215	transferase activity, transferring glycosyl groups
KU251_04690	COG0415	Belongs to the DNA photolyase family
KU251_04700	COG1252	NADH dehydrogenase
KU251_04705	COG1686	Belongs to the peptidase S11 family
KU251_04720	COG1187	pseudouridine synthase activity
KU251_04745	COG0477	Major facilitator Superfamily
KU251_04750	COG0583	DNA-binding transcription factor activity
KU251_04755	COG1823	symporter activity
KU251_04765	COG0612	Peptidase, M16
KU251_04790	COG0352	thiamine-phosphate diphosphorylase activity
KU251_04825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU251_04840	COG1309	transcriptional regulator
KU251_04850	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KU251_04855	COG0076	glutamate decarboxylase activity
KU251_04865	COG1522	sequence-specific DNA binding
KU251_04870	COG3961	Belongs to the TPP enzyme family
KU251_04875	COG1113	amino acid transport
KU251_04880	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KU251_04885	COG0573	inorganic phosphate transmembrane transporter activity
KU251_04895	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KU251_04900	COG0616	signal peptide processing
KU251_04935	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KU251_04940	COG1686	Belongs to the peptidase S11 family
KU251_04965	COG0583	DNA-binding transcription factor activity
KU251_04970	COG1067	ATP-dependent peptidase activity
KU251_05015	COG1966	Carbon starvation protein
KU251_05020	COG2879	small protein
KU251_05050	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KU251_05050	COG2508	Transcriptional regulator
KU251_05070	COG1113	amino acid transport
KU251_05075	COG0583	DNA-binding transcription factor activity
KU251_05080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU251_05085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU251_05095	COG1012	belongs to the aldehyde dehydrogenase family
KU251_05100	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU251_05105	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KU251_05105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KU251_05140	COG2814	Major facilitator Superfamily
KU251_05145	COG4948	Mandelate Racemase Muconate Lactonizing
KU251_05155	COG1309	transcriptional regulator
KU251_05175	COG1741	Belongs to the pirin family
KU251_05185	COG2964	Protein conserved in bacteria
KU251_05200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KU251_05205	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KU251_05210	COG4605	iron ion homeostasis
KU251_05215	COG4604	ABC transporter, ATP-binding protein
KU251_05220	COG4607	ABC-type enterochelin transport system periplasmic component
KU251_05225	COG4774	siderophore transport
KU251_05235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KU251_05240	COG1021	2,3-dihydroxybenzoate-AMP ligase
KU251_05245	COG3433	isochorismatase activity
KU251_05245	COG1535	isochorismatase
KU251_05260	COG1132	(ABC) transporter
KU251_05265	COG1132	(ABC) transporter
KU251_05270	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KU251_05280	COG1169	isochorismate synthase
KU251_05295	COG3739	integral membrane protein
KU251_05320	COG0302	gtp cyclohydrolase
KU251_05330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KU251_05360	COG0308	aminopeptidase N
KU251_05365	COG0512	Glutamine amidotransferase of anthranilate synthase
KU251_05545	COG5410	chromosome segregation
KU251_05710	COG0582	viral genome integration into host DNA
KU251_05725	COG0174	glutamine synthetase
KU251_05735	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KU251_05770	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KU251_05775	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KU251_05780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KU251_05800	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KU251_05805	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KU251_05810	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KU251_05825	COG1960	acyl-CoA dehydrogenase activity
KU251_05830	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KU251_05835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KU251_05845	COG2223	nitrite transmembrane transporter activity
KU251_05855	COG0024	Methionine aminopeptidase
KU251_05860	COG0052	Belongs to the universal ribosomal protein uS2 family
KU251_05875	COG2207	Transcriptional regulator
KU251_05900	COG2951	lytic endotransglycosylase activity
KU251_05905	COG0772	Belongs to the SEDS family
KU251_05920	COG0842	Transport permease protein
KU251_05925	COG1131	(ABC) transporter
KU251_05970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU251_05985	COG4215	(ABC) transporter
KU251_05990	COG4160	amino acid transport
KU251_05995	COG4598	ABC transporter
KU251_06005	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KU251_06010	COG0826	peptidase U32
KU251_06015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU251_06030	COG1720	tRNA m6t6A37 methyltransferase activity
KU251_06040	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KU251_06055	COG0642	Histidine kinase
KU251_06065	COG0494	nUDIX hydrolase
KU251_06075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KU251_06080	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KU251_06085	COG3139	Protein of unknown function (DUF1315)
KU251_06090	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KU251_06095	COG1301	dicarboxylic acid transport
KU251_06100	COG1960	acyl-CoA dehydrogenase activity
KU251_06105	COG2819	hydrolase of the alpha beta superfamily
KU251_06115	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KU251_06125	COG2195	Cleaves the N-terminal amino acid of tripeptides
KU251_06130	COG1234	tRNA 3'-trailer cleavage
KU251_06160	COG2363	Small membrane protein
KU251_06180	COG0513	Belongs to the DEAD box helicase family
KU251_06190	COG0778	Nitroreductase
KU251_06545	COG1286	toxin biosynthetic process
KU251_06570	COG4783	chaperone-mediated protein folding
KU251_06575	COG1610	YqeY-like protein
KU251_06675	COG3111	PFAM Bacterial OB fold (BOF) protein
KU251_06700	COG3243	poly(R)-hydroxyalkanoic acid synthase
KU251_06705	COG0786	glutamate:sodium symporter activity
KU251_06715	COG2186	Transcriptional regulator
KU251_06765	COG0477	Major facilitator Superfamily
KU251_06800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KU251_06805	COG2011	ABC-type metal ion transport system permease component
KU251_06810	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KU251_06815	COG1464	Belongs to the NlpA lipoprotein family
KU251_06820	COG0151	Belongs to the GarS family
KU251_06825	COG0138	bifunctional purine biosynthesis protein purh
KU251_06830	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KU251_06860	COG2308	Evidence 4 Homologs of previously reported genes of
KU251_06870	COG1305	Transglutaminase-like
KU251_06880	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KU251_06885	COG0305	Participates in initiation and elongation during chromosome replication
KU251_06910	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KU251_06920	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KU251_06925	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KU251_06950	COG0726	polysaccharide deacetylase
KU251_06950	COG1649	PFAM Uncharacterised BCR, COG1649
KU251_06955	COG1215	transferase activity, transferring glycosyl groups
KU251_06960	COG3658	cytochrome
KU251_06970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KU251_06985	COG0583	DNA-binding transcription factor activity
KU251_07005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU251_07010	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KU251_07025	COG1960	acyl-CoA dehydrogenase activity
KU251_07030	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KU251_07035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU251_07060	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KU251_07065	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KU251_07075	COG2205	protein histidine kinase activity
KU251_07080	COG0745	RESPONSE REGULATOR receiver
KU251_07085	COG0174	glutamine synthetase
KU251_07105	COG0729	surface antigen
KU251_07130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KU251_07135	COG2814	Major facilitator Superfamily
KU251_07230	COG4397	Mu-like prophage major head subunit gpT
KU251_07245	COG5005	Phage virion morphogenesis
KU251_07250	COG2369	cell adhesion
KU251_07255	COG4383	Mu-like prophage protein gp29
KU251_07270	COG4373	Mu-like prophage FluMu protein gp28
KU251_07305	COG0681	Belongs to the peptidase S26 family
KU251_07335	COG3409	Peptidoglycan-binding domain 1 protein
KU251_07335	COG3267	Type II secretory pathway component ExeA
KU251_07410	COG0583	DNA-binding transcription factor activity
KU251_07425	COG1187	pseudouridine synthase activity
KU251_07445	COG0802	atpase or kinase
KU251_07450	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KU251_07460	COG1923	regulation of RNA biosynthetic process
KU251_07465	COG0697	spore germination
KU251_07480	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KU251_07490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KU251_07495	COG0519	Catalyzes the synthesis of GMP from XMP
KU251_07495	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KU251_07500	COG4302	ethanolamine ammonia-lyase activity
KU251_07505	COG4303	Ethanolamine ammonia lyase large subunit
KU251_07510	COG0531	amino acid
KU251_07530	COG1454	alcohol dehydrogenase
KU251_07535	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KU251_07545	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
KU251_07565	COG0308	aminopeptidase N
KU251_07575	COG4221	oxidoreductase activity
KU251_07585	COG1605	Chorismate mutase
KU251_07600	COG1309	transcriptional regulator
KU251_07610	COG0668	transmembrane transport
KU251_07645	COG4773	Receptor
KU251_07665	COG0488	(ABC) transporter
KU251_07670	COG0589	response to stress
KU251_07695	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KU251_07705	COG3135	benzoate transporter
KU251_07710	COG1522	sequence-specific DNA binding
KU251_07720	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KU251_07725	COG0583	DNA-binding transcription factor activity
KU251_07735	COG0183	Belongs to the thiolase family
KU251_07745	COG2030	dehydratase
KU251_07750	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KU251_07765	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KU251_07775	COG0824	Thioesterase
KU251_07780	COG1454	alcohol dehydrogenase
KU251_07790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KU251_07810	COG0069	glutamate synthase activity
KU251_07830	COG2814	Major facilitator Superfamily
KU251_07845	COG0511	ligase activity, forming carbon-carbon bonds
KU251_07865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KU251_07865	COG1116	anion transmembrane transporter activity
KU251_07870	COG0745	RESPONSE REGULATOR receiver
KU251_07880	COG2146	nitrite reductase [NAD(P)H] activity
KU251_07880	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU251_07885	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU251_07890	COG0243	molybdopterin cofactor binding
KU251_07900	COG0243	molybdopterin cofactor binding
KU251_07905	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KU251_07920	COG0521	Mo-molybdopterin cofactor biosynthetic process
KU251_07920	COG0315	cyclic pyranopterin monophosphate synthase activity
KU251_07925	COG0303	'Molybdopterin
KU251_07935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU251_07940	COG0697	spore germination
KU251_07960	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KU251_07965	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KU251_08030	COG2204	response regulator
KU251_08035	COG3852	Histidine kinase
KU251_08060	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KU251_08065	COG0575	Belongs to the CDS family
KU251_08100	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KU251_08115	COG2137	regulation of response to DNA damage stimulus
KU251_08125	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KU251_08130	COG1011	Hydrolase
KU251_08155	COG1522	sequence-specific DNA binding
KU251_08165	COG1113	amino acid transport
KU251_08180	COG0659	secondary active sulfate transmembrane transporter activity
KU251_08185	COG2135	peptidase activity
KU251_08200	COG3300	MHYT domain
KU251_08200	COG5001	Diguanylate cyclase
KU251_08220	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KU251_08220	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KU251_08220	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KU251_08225	COG1105	Belongs to the carbohydrate kinase PfkB family
KU251_08230	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KU251_08230	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KU251_08260	COG0024	Methionine aminopeptidase
KU251_08265	COG0583	DNA-binding transcription factor activity
KU251_08275	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KU251_08280	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KU251_08285	COG0516	GMP reductase activity
KU251_08285	COG0517	IMP dehydrogenase activity
KU251_08310	COG0552	protein localization to endoplasmic reticulum
KU251_08320	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
KU251_08335	COG4890	Cyd operon protein YbgT
KU251_08340	COG1294	oxidase, subunit
KU251_08355	COG1585	Membrane protein implicated in regulation of membrane protease activity
KU251_08365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KU251_08370	COG4774	siderophore transport
KU251_08385	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KU251_08390	COG0569	domain protein
KU251_08395	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KU251_08425	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KU251_08430	COG0542	response to heat
KU251_08455	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU251_08455	COG1902	pentaerythritol trinitrate reductase activity
KU251_08500	COG2323	membrane
KU251_08505	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KU251_08515	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KU251_08520	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KU251_08525	COG0183	Belongs to the thiolase family
KU251_08530	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KU251_08535	COG0596	Alpha beta hydrolase
KU251_08540	COG2271	Major facilitator Superfamily
KU251_08545	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KU251_08550	COG3485	protocatechuate 3,4-dioxygenase
KU251_08555	COG3485	protocatechuate 3,4-dioxygenase
KU251_08560	COG0710	3-dehydroquinate dehydratase activity
KU251_08565	COG3420	alginic acid biosynthetic process
KU251_08570	COG3659	wide pore channel activity
KU251_08575	COG4993	Dehydrogenase
KU251_08585	COG2391	methyltransferase activity
KU251_08600	COG1414	Transcriptional regulator
KU251_08605	COG0583	DNA-binding transcription factor activity
KU251_08610	COG1960	acyl-CoA dehydrogenase activity
KU251_08635	COG2814	Major facilitator Superfamily
KU251_08645	COG0154	amidase activity
KU251_08665	COG4638	Rieske (2fe-2S)
KU251_08675	COG1028	Short-chain dehydrogenase reductase Sdr
KU251_08685	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU251_08695	COG3733	amine oxidase
KU251_08705	COG1012	belongs to the aldehyde dehydrogenase family
KU251_08715	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KU251_08720	COG0183	Belongs to the thiolase family
KU251_08725	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KU251_08730	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KU251_08740	COG4829	muconolactone delta-isomerase
KU251_08745	COG4948	Mandelate Racemase Muconate Lactonizing
KU251_08750	COG0583	DNA-binding transcription factor activity
KU251_08760	COG2186	Transcriptional regulator
KU251_08780	COG1012	belongs to the aldehyde dehydrogenase family
KU251_08800	COG1960	acyl-CoA dehydrogenase activity
KU251_08805	COG1028	Short-chain dehydrogenase reductase Sdr
KU251_08810	COG3829	transcription factor binding
KU251_08820	COG3162	membrane
KU251_08835	COG1012	belongs to the aldehyde dehydrogenase family
KU251_08850	COG0753	catalase activity
KU251_08870	COG1846	Transcriptional regulator
KU251_08875	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU251_08875	COG1902	pentaerythritol trinitrate reductase activity
KU251_08885	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KU251_08915	COG1309	transcriptional regulator
KU251_08925	COG1335	isochorismatase
KU251_08930	COG0583	DNA-binding transcription factor activity
KU251_08940	COG0475	glutathione-regulated potassium exporter activity
KU251_08940	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KU251_08950	COG1473	amidohydrolase
KU251_08960	COG2831	hemolysin activation secretion protein
KU251_08965	COG3210	domain, Protein
KU251_08995	COG2188	Transcriptional regulator
KU251_09010	COG0583	DNA-binding transcription factor activity
KU251_09040	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KU251_09060	COG1566	PFAM secretion protein HlyD family protein
KU251_09075	COG1012	belongs to the aldehyde dehydrogenase family
KU251_09080	COG0129	dihydroxy-acid dehydratase activity
KU251_09090	COG0583	DNA-binding transcription factor activity
KU251_09095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KU251_09105	COG2084	Dehydrogenase
KU251_09110	COG2207	Transcriptional regulator
KU251_09125	COG1064	alcohol dehydrogenase
KU251_09135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KU251_09140	COG1120	ATPase activity
KU251_09160	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KU251_09275	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KU251_09325	COG1028	Short-chain dehydrogenase reductase Sdr
KU251_09340	COG2207	Transcriptional regulator
KU251_09350	COG2205	protein histidine kinase activity
KU251_09355	COG0745	RESPONSE REGULATOR receiver
KU251_09360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU251_09365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KU251_09370	COG1538	Outer membrane efflux protein
KU251_09380	COG2072	flavoprotein involved in K transport
KU251_09400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KU251_09420	COG3539	Fimbrial protein
KU251_09450	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KU251_09460	COG0753	catalase activity
KU251_09475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KU251_09535	COG1535	isochorismatase
KU251_09535	COG3433	isochorismatase activity
KU251_09540	COG1028	Short-chain dehydrogenase reductase Sdr
KU251_09545	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KU251_09550	COG4149	molybdate abc transporter
KU251_09555	COG0725	ABC transporter, periplasmic molybdate-binding protein
KU251_09565	COG4638	Rieske (2fe-2S)
KU251_09570	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KU251_09575	COG0543	2 iron, 2 sulfur cluster binding
KU251_09575	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU251_09600	COG1028	Short-chain dehydrogenase reductase Sdr
KU251_09615	COG2207	Transcriptional regulator
KU251_09630	COG2610	gluconate transmembrane transporter activity
KU251_09645	COG0583	DNA-binding transcription factor activity
KU251_09655	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KU251_09660	COG2031	fatty acid transporter
KU251_09665	COG0183	Belongs to the thiolase family
KU251_09670	COG0583	DNA-binding transcription factor activity
KU251_09675	COG0583	DNA-binding transcription factor activity
KU251_09690	COG1027	Aspartate ammonia-lyase
KU251_09700	COG0477	Major facilitator Superfamily
KU251_09720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU251_09725	COG4521	taurine ABC transporter
KU251_09740	COG2188	Transcriptional regulator
KU251_09750	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KU251_09755	COG1733	regulation of RNA biosynthetic process
KU251_09760	COG3708	Transcriptional regulator
KU251_09760	COG2207	Transcriptional regulator
KU251_09775	COG0730	response to heat
KU251_09785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KU251_09785	COG3453	Protein conserved in bacteria
KU251_09795	COG3781	membrane
KU251_09800	COG1063	alcohol dehydrogenase
KU251_09810	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KU251_09815	COG0508	dehydrogenase complex catalyzes the overall conversion of
KU251_09820	COG0022	dehydrogenase e1 component
KU251_09825	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KU251_09830	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KU251_09845	COG3706	GGDEF domain
KU251_09860	COG0133	tryptophan synthase activity
KU251_09870	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KU251_09905	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KU251_09930	COG2226	methyltransferase
KU251_09985	COG0842	Transport permease protein
KU251_09990	COG0842	Transport permease protein
KU251_09995	COG1131	(ABC) transporter
KU251_10010	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KU251_10015	COG4773	Receptor
KU251_10035	COG0730	response to heat
KU251_10040	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KU251_10060	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KU251_10075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KU251_10115	COG4264	IucA IucC family
KU251_10120	COG4264	IucA IucC family
KU251_10140	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KU251_10160	COG1960	acyl-CoA dehydrogenase activity
KU251_10165	COG1960	acyl-CoA dehydrogenase activity
KU251_10170	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KU251_10175	COG2207	Transcriptional regulator
KU251_10180	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KU251_10185	COG0776	regulation of translation
KU251_10210	COG0822	iron-sulfur transferase activity
KU251_10215	COG0316	Belongs to the HesB IscA family
KU251_10245	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KU251_10265	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KU251_10270	COG0702	epimerase
KU251_10305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KU251_10315	COG0339	signal peptide processing
KU251_10375	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KU251_10380	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KU251_10410	COG0776	regulation of translation
KU251_10475	COG0084	hydrolase, TatD family'
KU251_10495	COG1663	tetraacyldisaccharide 4'-kinase activity
KU251_10500	COG1132	(ABC) transporter
KU251_10510	COG0811	peptide transport
KU251_10515	COG1475	DNA binding
KU251_10520	COG1192	Involved in chromosome partitioning
KU251_10530	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KU251_10545	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KU251_10550	COG0191	fructose-bisphosphate aldolase activity
KU251_10570	COG0424	maF-like protein
KU251_10575	COG2850	peptidyl-arginine hydroxylation
KU251_10585	COG0640	Transcriptional regulator
KU251_10595	COG3619	membrane
KU251_10600	COG3122	Protein conserved in bacteria
KU251_10605	COG1132	(ABC) transporter
KU251_10625	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KU251_10630	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KU251_10640	COG0506	proline dehydrogenase activity
KU251_10640	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KU251_10640	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KU251_10645	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KU251_10660	COG3698	Phosphodiester glycosidase
KU251_10670	COG2353	YceI-like domain
KU251_10680	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KU251_10725	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KU251_10725	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KU251_10750	COG3539	Fimbrial protein
KU251_10755	COG3121	Chaperone
KU251_10780	COG0697	spore germination
KU251_10790	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KU251_10800	COG0583	DNA-binding transcription factor activity
KU251_10820	COG1309	transcriptional regulator
KU251_10850	COG1126	abc transporter atp-binding protein
KU251_10855	COG0765	amino acid transport
KU251_10860	COG0765	amino acid transport
KU251_10890	COG1464	Belongs to the NlpA lipoprotein family
KU251_10910	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KU251_10915	COG2011	ABC-type metal ion transport system permease component
KU251_10920	COG0012	GTP binding
KU251_10945	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KU251_10985	COG0386	Belongs to the glutathione peroxidase family
KU251_10995	COG0436	Aminotransferase
KU251_11035	COG3634	alkyl hydroperoxide reductase activity
KU251_11050	COG0583	DNA-binding transcription factor activity
KU251_11055	COG0798	PFAM Bile acid sodium symporter
KU251_11060	COG0640	Transcriptional regulator
KU251_11075	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KU251_11105	COG1953	Uracil, thiamine, allantoin
KU251_11115	COG2175	clavaminate synthase activity
KU251_11120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU251_11125	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KU251_11130	COG4521	taurine ABC transporter
KU251_11140	COG0477	Major facilitator Superfamily
KU251_11160	COG1271	oxidase subunit
KU251_11165	COG1294	oxidase, subunit
KU251_11175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU251_11195	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KU251_11215	COG3052	prosthetic group binding
KU251_11220	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
KU251_11230	COG2814	Major facilitator Superfamily
KU251_11250	COG1346	cytolysis
KU251_11260	COG0583	DNA-binding transcription factor activity
KU251_11265	COG0625	glutathione transferase activity
KU251_11270	COG0625	glutathione transferase activity
KU251_11275	COG0583	DNA-binding transcription factor activity
KU251_11290	COG1045	serine acetyltransferase
KU251_11295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KU251_11300	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KU251_11310	COG1280	lysine exporter protein (LysE YggA)
KU251_11325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KU251_11330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KU251_11335	COG1126	abc transporter atp-binding protein
KU251_11340	COG0765	amino acid transport
KU251_11345	COG0765	amino acid transport
KU251_11365	COG0784	Response regulator, receiver
KU251_11365	COG2205	protein histidine kinase activity
KU251_11385	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KU251_11405	COG1028	Short-chain dehydrogenase reductase Sdr
KU251_11455	COG0583	DNA-binding transcription factor activity
KU251_11475	COG0318	PFAM AMP-dependent synthetase and ligase
KU251_11480	COG1309	transcriptional regulator
KU251_11485	COG1960	acyl-CoA dehydrogenase activity
KU251_11490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KU251_11495	COG1024	Enoyl-CoA hydratase
KU251_11500	COG4770	biotin carboxylase activity
KU251_11510	COG0583	DNA-binding transcription factor activity
KU251_11525	COG1960	acyl-CoA dehydrogenase activity
KU251_11535	COG2814	Major facilitator Superfamily
KU251_11545	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KU251_11550	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KU251_11555	COG2814	Major facilitator Superfamily
KU251_11560	COG1960	acyl-CoA dehydrogenase activity
KU251_11565	COG1024	Enoyl-CoA hydratase
KU251_11570	COG1028	Short-chain dehydrogenase reductase Sdr
KU251_11575	COG1250	3-hydroxyacyl-CoA dehydrogenase
KU251_11580	COG0183	Belongs to the thiolase family
KU251_11590	COG2814	Major facilitator Superfamily
KU251_11600	COG1024	Enoyl-CoA hydratase
KU251_11615	COG1960	acyl-CoA dehydrogenase activity
KU251_11620	COG2814	Major facilitator Superfamily
KU251_11625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KU251_11630	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KU251_11645	COG3842	ATPase activity
KU251_11650	COG1840	ABC-type Fe3 transport system, periplasmic component
KU251_11660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU251_11665	COG1414	Transcriptional regulator
KU251_11675	COG0583	DNA-binding transcription factor activity
KU251_11680	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KU251_11685	COG1012	belongs to the aldehyde dehydrogenase family
KU251_11695	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KU251_11705	COG1012	belongs to the aldehyde dehydrogenase family
KU251_11710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KU251_11715	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU251_11720	COG2267	carboxylic ester hydrolase activity
KU251_11740	COG3038	cytochrome b561
KU251_11745	COG0753	catalase activity
KU251_11780	COG2050	protein possibly involved in aromatic compounds catabolism
KU251_11790	COG3327	negative regulation of DNA-templated transcription, initiation
KU251_11795	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
KU251_11800	COG0183	Belongs to the thiolase family
KU251_11805	COG1250	3-hydroxyacyl-CoA dehydrogenase
KU251_11810	COG1024	Enoyl-CoA hydratase
KU251_11815	COG1024	Enoyl-CoA hydratase
KU251_11820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU251_11825	COG2151	metal-sulfur cluster biosynthetic enzyme
KU251_11830	COG3396	Phenylacetate-CoA oxygenase
KU251_11835	COG3460	Phenylacetate-CoA oxygenase
KU251_11840	COG3396	Phenylacetate-CoA oxygenase
KU251_11845	COG1012	belongs to the aldehyde dehydrogenase family
KU251_11845	COG2030	dehydratase
KU251_11850	COG1760	l-serine dehydratase
KU251_11855	COG0531	amino acid
KU251_11860	COG1012	belongs to the aldehyde dehydrogenase family
KU251_11875	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU251_11885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KU251_11905	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU251_11915	COG0789	Transcriptional regulator
KU251_11930	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KU251_11945	COG2807	transmembrane transport
KU251_11950	COG0590	tRNA wobble adenosine to inosine editing
KU251_12065	COG1116	anion transmembrane transporter activity
KU251_12070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KU251_12080	COG0864	Transcriptional regulator
KU251_12100	COG2249	NAD(P)H dehydrogenase (quinone) activity
KU251_12105	COG0439	Biotin carboxylase
KU251_12120	COG1063	alcohol dehydrogenase
KU251_12130	COG1309	transcriptional regulator
KU251_12150	COG0038	chloride channel
KU251_12155	COG4770	biotin carboxylase activity
KU251_12175	COG1914	H( )-stimulated, divalent metal cation uptake system
KU251_12180	COG0583	DNA-binding transcription factor activity
KU251_12230	COG1250	3-hydroxyacyl-CoA dehydrogenase
KU251_12250	COG2814	Major facilitator Superfamily
KU251_12260	COG1560	Kdo2-lipid A biosynthetic process
KU251_12275	COG5006	permease, DMT superfamily
KU251_12280	COG1522	sequence-specific DNA binding
KU251_12295	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KU251_12305	COG4122	O-methyltransferase activity
KU251_12335	COG1538	Outer membrane efflux protein
KU251_12340	COG1137	ATPase activity
KU251_12345	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KU251_12355	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KU251_12360	COG0517	IMP dehydrogenase activity
KU251_12360	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KU251_12405	COG2814	Major facilitator Superfamily
KU251_12440	COG1278	Cold shock
KU251_12445	COG1280	lysine exporter protein (LysE YggA)
KU251_12475	COG1570	exodeoxyribonuclease VII activity
KU251_12525	COG0583	DNA-binding transcription factor activity
KU251_12530	COG4638	Rieske (2fe-2S)
KU251_12535	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KU251_12540	COG0543	2 iron, 2 sulfur cluster binding
KU251_12540	COG0633	Ferredoxin
KU251_12545	COG1028	Short-chain dehydrogenase reductase Sdr
KU251_12550	COG3135	benzoate transporter
KU251_12555	COG2814	Major facilitator Superfamily
KU251_12570	COG1643	Atp-dependent helicase
KU251_12575	COG0450	alkyl hydroperoxide reductase
KU251_12585	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KU251_12595	COG3634	alkyl hydroperoxide reductase activity
KU251_12615	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KU251_12620	COG0625	glutathione transferase activity
KU251_12630	COG2885	chlorophyll binding
KU251_12665	COG0542	response to heat
KU251_12680	COG1765	OsmC-like protein
KU251_12700	COG0667	Aldo Keto reductase
KU251_12715	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KU251_12725	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KU251_12735	COG0527	aspartate kinase activity
KU251_12745	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KU251_12755	COG3038	cytochrome b561
KU251_12760	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KU251_12765	COG2252	PERMEase
KU251_12775	COG2072	flavoprotein involved in K transport
KU251_12790	COG1741	Belongs to the pirin family
KU251_12795	COG1309	transcriptional regulator
KU251_12805	COG0300	oxidoreductase activity
KU251_12865	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KU251_12895	COG1113	amino acid transport
KU251_12915	COG1012	belongs to the aldehyde dehydrogenase family
KU251_12935	COG0531	amino acid
KU251_12945	COG1113	amino acid transport
KU251_12985	COG3209	COG3209 Rhs family protein
KU251_13015	COG4269	membrane
KU251_13030	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU251_13030	COG1902	pentaerythritol trinitrate reductase activity
KU251_13040	COG2203	Gaf domain
KU251_13040	COG3706	GGDEF domain
KU251_13040	COG4251	negative regulation of phosphorylation
KU251_13040	COG5001	Diguanylate cyclase
KU251_13050	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KU251_13070	COG4172	Belongs to the ABC transporter superfamily
KU251_13075	COG4239	(ABC) transporter, permease
KU251_13080	COG4174	ABC transporter (Permease)
KU251_13090	COG1388	LysM domain
KU251_13090	COG0741	lytic transglycosylase activity
KU251_13090	COG0741	lytic transglycosylase activity
KU251_13090	COG1388	LysM domain
KU251_13095	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KU251_13135	COG0583	DNA-binding transcription factor activity
KU251_13140	COG1279	arginine transmembrane transporter activity
KU251_13160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU251_13165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU251_13170	COG0006	proline dipeptidase activity
KU251_13255	COG1196	nuclear chromosome segregation
KU251_13255	COG0741	lytic transglycosylase activity
KU251_13255	COG0739	heme binding
KU251_13315	COG4695	Portal protein
KU251_13410	COG0305	Participates in initiation and elongation during chromosome replication
KU251_13425	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KU251_13480	COG2194	sulfuric ester hydrolase activity
KU251_13525	COG0739	heme binding
KU251_13850	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KU251_13875	COG3384	dioxygenase
KU251_13885	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KU251_13890	COG2878	Part of a membrane complex involved in electron transport
KU251_13895	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KU251_13920	COG0768	penicillin binding
KU251_13925	COG0742	ribosomal rna small subunit methyltransferase
KU251_13940	COG0830	nickel cation binding
KU251_13985	COG1253	flavin adenine dinucleotide binding
KU251_14040	COG1773	rubredoxin
KU251_14045	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU251_14055	COG0583	DNA-binding transcription factor activity
KU251_14080	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KU251_14085	COG4181	ATPase activity
KU251_14130	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KU251_14150	COG0306	phosphate transporter
KU251_14160	COG3958	Transketolase
KU251_14165	COG3959	Transketolase, thiamine diphosphate binding domain
KU251_14170	COG2271	Major facilitator Superfamily
KU251_14175	COG1028	Short-chain dehydrogenase reductase Sdr
KU251_14180	COG0583	DNA-binding transcription factor activity
KU251_14195	COG2223	nitrite transmembrane transporter activity
KU251_14200	COG2207	Transcriptional regulator
KU251_14205	COG2066	Belongs to the glutaminase family
KU251_14210	COG0242	peptide deformylase activity
KU251_14215	COG0477	Major facilitator Superfamily
KU251_14225	COG0028	Belongs to the TPP enzyme family
KU251_14240	COG1028	Short-chain dehydrogenase reductase Sdr
KU251_14245	COG2267	carboxylic ester hydrolase activity
KU251_14255	COG2271	Major facilitator Superfamily
KU251_14260	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU251_14270	COG1028	Short-chain dehydrogenase reductase Sdr
KU251_14290	COG1414	Transcriptional regulator
KU251_14305	COG1024	Enoyl-CoA hydratase
KU251_14315	COG1215	transferase activity, transferring glycosyl groups
KU251_14320	COG1649	PFAM Uncharacterised BCR, COG1649
KU251_14320	COG0726	polysaccharide deacetylase
KU251_14330	COG4681	YaeQ
KU251_14340	COG0523	cobalamin synthesis protein
KU251_14350	COG1607	acyl-coa hydrolase
KU251_14360	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU251_14365	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU251_14370	COG1309	transcriptional regulator
KU251_14395	COG2040	homocysteine
KU251_14400	COG0531	amino acid
KU251_14455	COG1595	DNA-templated transcription, initiation
KU251_14465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU251_14470	COG0477	Major facilitator Superfamily
KU251_14490	COG0084	hydrolase, TatD family'
KU251_14525	COG0629	single-stranded DNA binding
KU251_14580	COG0582	viral genome integration into host DNA
KU251_14610	COG1061	Type III restriction enzyme res subunit
KU251_14620	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KU251_14625	COG1192	Involved in chromosome partitioning
KU251_14740	COG0592	DNA-directed DNA polymerase activity
KU251_14780	COG2026	Addiction module toxin, RelE StbE family
KU251_14980	COG1484	DNA-dependent DNA replication
KU251_15070	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KU251_15140	COG0405	Gamma-glutamyltransferase
KU251_15145	COG2814	Major facilitator Superfamily
KU251_15155	COG2050	protein possibly involved in aromatic compounds catabolism
KU251_15170	COG1090	epimerase
KU251_15190	COG0420	3'-5' exonuclease activity
KU251_15215	COG0735	belongs to the Fur family
KU251_15220	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KU251_15240	COG0121	glutamine amidotransferase
KU251_15255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KU251_15265	COG0210	DNA helicase
KU251_15270	COG2885	chlorophyll binding
KU251_15275	COG0204	Acyl-transferase
KU251_15290	COG2894	cell division
KU251_15310	COG1280	lysine exporter protein (LysE YggA)
KU251_15315	COG1674	ftsk spoiiie
KU251_15315	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KU251_15320	COG0492	ferredoxin-NADP+ reductase activity
KU251_15325	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KU251_15335	COG0456	acetyltransferase
KU251_15380	COG1981	membrane
KU251_15395	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KU251_15395	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KU251_15415	COG1012	belongs to the aldehyde dehydrogenase family
KU251_15425	COG0657	acetylesterase activity
KU251_15435	COG0473	3-isopropylmalate dehydrogenase activity
KU251_15440	COG0583	DNA-binding transcription factor activity
KU251_15460	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KU251_15485	COG0564	pseudouridine synthase activity
KU251_15495	COG0358	DNA primase activity
KU251_15510	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KU251_15540	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KU251_15570	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KU251_15580	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KU251_15580	COG0351	phosphomethylpyrimidine kinase
KU251_15580	COG0352	thiamine-phosphate diphosphorylase activity
KU251_15585	COG1652	LysM domain
KU251_15610	COG1399	metal-binding, possibly nucleic acid-binding protein
KU251_15615	COG3101	peptidyl-lysine hydroxylation
KU251_15620	COG0009	L-threonylcarbamoyladenylate synthase
KU251_15625	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KU251_15630	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KU251_15645	COG4106	trans-aconitate 2-methyltransferase activity
KU251_15660	COG0596	Alpha beta hydrolase
KU251_15660	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KU251_15660	COG2226	methyltransferase
KU251_15665	COG1877	trehalose-phosphatase activity
KU251_15670	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
KU251_15675	COG2223	nitrite transmembrane transporter activity
KU251_15695	COG1196	nuclear chromosome segregation
KU251_15705	COG0730	response to heat
KU251_15720	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KU251_15730	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KU251_15780	COG0489	protein tyrosine kinase activity
KU251_15790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KU251_15790	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KU251_15820	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KU251_15825	COG2081	HI0933 family
KU251_15835	COG0668	transmembrane transport
KU251_15855	COG0583	DNA-binding transcription factor activity
KU251_15875	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KU251_15880	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KU251_15910	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KU251_15950	COG0745	RESPONSE REGULATOR receiver
KU251_15970	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KU251_15980	COG2205	protein histidine kinase activity
KU251_16050	COG4993	Dehydrogenase
KU251_16075	COG0384	phenazine biosynthesis protein PhzF
KU251_16095	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU251_16110	COG0583	DNA-binding transcription factor activity
KU251_16140	COG0583	DNA-binding transcription factor activity
KU251_16155	COG0583	DNA-binding transcription factor activity
KU251_16160	COG1053	succinate dehydrogenase
KU251_16170	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KU251_16175	COG2814	Major facilitator Superfamily
KU251_16180	COG1960	acyl-CoA dehydrogenase activity
KU251_16185	COG0583	DNA-binding transcription factor activity
KU251_16190	COG1063	alcohol dehydrogenase
KU251_16220	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KU251_16225	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KU251_16230	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KU251_16245	COG3667	copper resistance
KU251_16250	COG2132	Multicopper oxidase
KU251_16260	COG0561	phosphatase activity
KU251_16265	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KU251_16290	COG1214	PFAM Peptidase M22, glycoprotease
KU251_16340	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KU251_16350	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KU251_16355	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KU251_16360	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KU251_16420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KU251_16430	COG1846	Transcriptional regulator
KU251_16435	COG1764	response to oxidative stress
KU251_16475	COG0037	tRNA processing
KU251_16485	COG0248	Ppx GppA phosphatase
KU251_16515	COG0072	phenylalanine-tRNA ligase activity
KU251_16555	COG1238	metal cluster binding
KU251_16560	COG0625	glutathione transferase activity
KU251_16575	COG0318	PFAM AMP-dependent synthetase and ligase
KU251_16580	COG3028	Belongs to the UPF0307 family
KU251_16585	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KU251_16605	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KU251_16610	COG0617	tRNA 3'-terminal CCA addition
KU251_16615	COG1555	photosystem II stabilization
KU251_16620	COG3956	TIGRFAM MazG family protein
KU251_16630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KU251_16650	COG5002	protein histidine kinase activity
KU251_16650	COG0784	Response regulator, receiver
KU251_16650	COG2205	protein histidine kinase activity
KU251_16655	COG1024	Enoyl-CoA hydratase
KU251_16660	COG2084	Dehydrogenase
KU251_16665	COG3622	Belongs to the hyi family
KU251_16695	COG0697	spore germination
KU251_16705	COG2814	Major facilitator Superfamily
KU251_16710	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KU251_16720	COG0583	DNA-binding transcription factor activity
KU251_16730	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KU251_16745	COG0084	hydrolase, TatD family'
KU251_16760	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KU251_16790	COG0440	acetolactate synthase activity
KU251_16795	COG0028	Belongs to the TPP enzyme family
KU251_16820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU251_16825	COG0577	efflux transmembrane transporter activity
KU251_16825	COG1136	(ABC) transporter
KU251_16830	COG1538	Outer membrane efflux protein
KU251_16845	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KU251_16850	COG1162	GTPase activity
KU251_16860	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KU251_16880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KU251_16885	COG1028	Short-chain dehydrogenase reductase Sdr
KU251_16925	COG2986	histidine ammonia-lyase
KU251_16940	COG0318	PFAM AMP-dependent synthetase and ligase
KU251_16950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KU251_16995	COG1426	Protein conserved in bacteria
KU251_17030	COG0793	Belongs to the peptidase S41A family
KU251_17045	COG2267	carboxylic ester hydrolase activity
KU251_17055	COG1012	belongs to the aldehyde dehydrogenase family
KU251_17060	COG3265	gluconokinase activity
KU251_17070	COG0800	Aldolase
KU251_17080	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KU251_17085	COG0280	phosphate acetyltransferase
KU251_17085	COG0857	belongs to the CobB CobQ family
KU251_17090	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KU251_17090	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KU251_17110	COG0740	serine-type endopeptidase activity
KU251_17120	COG4774	siderophore transport
KU251_17130	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KU251_17140	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KU251_17140	COG2813	Specifically methylates the guanine in position
KU251_17240	COG0788	formyltetrahydrofolate deformylase activity
KU251_17265	COG4651	solute:proton antiporter activity
KU251_17265	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KU251_17285	COG0724	RNA recognition motif
KU251_17290	COG0210	DNA helicase
KU251_17315	COG1733	regulation of RNA biosynthetic process
KU251_17325	COG2900	Belongs to the SlyX family
KU251_17330	COG0488	(ABC) transporter
KU251_17335	COG1280	lysine exporter protein (LysE YggA)
KU251_17340	COG1560	Kdo2-lipid A biosynthetic process
KU251_17350	COG1301	dicarboxylic acid transport
KU251_17405	COG0473	3-isopropylmalate dehydrogenase activity
KU251_17470	COG0583	DNA-binding transcription factor activity
KU251_17480	COG0625	glutathione transferase activity
KU251_17485	COG2378	regulation of single-species biofilm formation
KU251_17490	COG0546	phosphoglycolate phosphatase activity
KU251_17500	COG1530	ribonuclease E activity
KU251_17505	COG0318	PFAM AMP-dependent synthetase and ligase
KU251_17520	COG0583	DNA-binding transcription factor activity
KU251_17525	COG4221	oxidoreductase activity
KU251_17530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KU251_17540	COG0534	Mate efflux family protein
KU251_17555	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KU251_17595	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KU251_17600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KU251_17615	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KU251_17625	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
KU251_17625	COG0644	oxidoreductase
KU251_17630	COG0425	Belongs to the sulfur carrier protein TusA family
KU251_17635	COG4535	Mg2 and Co2 transporter CorC
KU251_17645	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KU251_17665	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KU251_17670	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KU251_17670	COG0475	glutathione-regulated potassium exporter activity
KU251_17675	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KU251_17685	COG0484	heat shock protein binding
KU251_17690	COG0789	Transcriptional regulator
KU251_17695	COG0598	Magnesium transport protein CorA
KU251_17710	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KU251_17715	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KU251_17720	COG1074	ATP-dependent DNA helicase activity
KU251_17725	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KU251_17745	COG2226	methyltransferase
KU251_17760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU251_17765	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KU251_17780	COG2111	Na H antiporter
KU251_17780	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KU251_17785	COG1006	Multisubunit Na H antiporter MnhC subunit
KU251_17790	COG0651	ATP synthesis coupled electron transport
KU251_17795	COG1863	multisubunit Na H antiporter MnhE subunit
KU251_17800	COG2212	antiporter activity
KU251_17805	COG1320	monovalent cation:proton antiporter activity
KU251_17820	COG0195	Participates in both transcription termination and antitermination
KU251_17870	COG0237	dephospho-CoA kinase activity
KU251_17880	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KU251_17895	COG0497	DNA recombination
KU251_17905	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KU251_17935	COG2169	Transcriptional regulator
KU251_17935	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KU251_17940	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KU251_18005	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KU251_18020	COG0326	Molecular chaperone. Has ATPase activity
KU251_18035	COG2056	Na+-H+ antiporter family
KU251_18040	COG0596	Alpha beta hydrolase
KU251_18135	COG0546	phosphoglycolate phosphatase activity
KU251_18140	COG1716	ATPase activity
KU251_18185	COG0181	hydroxymethylbilane synthase activity
KU251_18195	COG3275	phosphorelay sensor kinase activity
KU251_18215	COG1538	Outer membrane efflux protein
KU251_18220	COG0697	spore germination
KU251_18245	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KU251_18250	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KU251_18255	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KU251_18260	COG0772	Belongs to the SEDS family
KU251_18285	COG4974	Belongs to the 'phage' integrase family
KU251_18290	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KU251_18300	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KU251_18310	COG2197	response regulator
KU251_18325	COG0793	Belongs to the peptidase S41A family
KU251_18330	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KU251_18335	COG0795	lipopolysaccharide-transporting ATPase activity
KU251_18375	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KU251_18375	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KU251_18385	COG0004	ammonium transporteR
KU251_18390	COG0347	Belongs to the P(II) protein family
KU251_18400	COG0606	chelatase, subunit chli
KU251_18450	COG0659	secondary active sulfate transmembrane transporter activity
KU251_18455	COG0589	response to stress
KU251_18485	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KU251_18530	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KU251_18560	COG0659	secondary active sulfate transmembrane transporter activity
KU251_18565	COG0589	response to stress
KU251_18595	COG0606	chelatase, subunit chli
KU251_18600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU251_18610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU251_18625	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KU251_18640	COG0318	PFAM AMP-dependent synthetase and ligase
KU251_18650	COG0477	Major facilitator Superfamily
KU251_18655	COG2860	membrane
KU251_18665	COG1253	flavin adenine dinucleotide binding
KU251_18685	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KU251_18720	COG0655	NAD(P)H dehydrogenase (quinone) activity
KU251_18730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KU251_18765	COG1309	transcriptional regulator
KU251_18800	COG0758	DNA mediated transformation
KU251_18810	COG0697	spore germination
KU251_18815	COG1309	transcriptional regulator
KU251_18830	COG0386	Belongs to the glutathione peroxidase family
KU251_18895	COG1121	(ABC) transporter
KU251_18900	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KU251_18905	COG1280	lysine exporter protein (LysE YggA)
KU251_18910	COG2837	iron assimilation
KU251_18920	COG0281	malic enzyme
KU251_18965	COG0519	Catalyzes the synthesis of GMP from XMP
KU251_18965	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KU251_18970	COG4399	Belongs to the UPF0754 family
KU251_18975	COG2259	Doxx family
KU251_18980	COG0586	Pfam SNARE associated Golgi protein
KU251_18995	COG1192	Involved in chromosome partitioning
KU251_19005	COG0271	Belongs to the BolA IbaG family
KU251_19025	COG2267	carboxylic ester hydrolase activity
KU251_19045	COG3321	synthase
KU251_19045	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KU251_19045	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KU251_19045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KU251_19050	COG1960	acyl-CoA dehydrogenase activity
KU251_19060	COG2197	response regulator
KU251_19070	COG3916	Acyl-homoserine-lactone synthase
KU251_19075	COG0477	Major facilitator Superfamily
KU251_19080	COG1024	Enoyl-CoA hydratase
KU251_19085	COG1024	Enoyl-CoA hydratase
KU251_19090	COG1960	acyl-CoA dehydrogenase activity
KU251_19095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KU251_19115	COG1113	amino acid transport
KU251_19120	COG1113	amino acid transport
KU251_19125	COG0251	oxidation-reduction process
KU251_19165	COG0564	pseudouridine synthase activity
KU251_19225	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KU251_19240	COG1802	Transcriptional regulator
KU251_19250	COG1448	Aminotransferase
KU251_19255	COG0277	FAD linked oxidase domain protein
KU251_19265	COG2186	Transcriptional regulator
KU251_19275	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KU251_19280	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KU251_19295	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KU251_19300	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KU251_19325	COG2244	polysaccharide biosynthetic process
KU251_19330	COG1083	cytidylyl-transferase
KU251_19335	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KU251_19345	COG2089	acid synthase
KU251_19350	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KU251_19355	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KU251_19365	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KU251_19370	COG1596	polysaccharide export
KU251_19395	COG0728	peptidoglycan biosynthetic process
KU251_19400	COG3023	N-Acetylmuramoyl-L-alanine amidase
KU251_19455	COG0546	phosphoglycolate phosphatase activity
KU251_19460	COG1028	Short-chain dehydrogenase reductase Sdr
KU251_19480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KU251_19485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KU251_19490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KU251_19495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU251_19500	COG1116	anion transmembrane transporter activity
KU251_19505	COG1309	transcriptional regulator
KU251_19510	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KU251_19520	COG0196	riboflavin kinase activity
KU251_19525	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KU251_19535	COG1047	Peptidyl-prolyl cis-trans
KU251_19575	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KU251_19580	COG0657	acetylesterase activity
KU251_19630	COG2951	lytic endotransglycosylase activity
KU251_19635	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KU251_19650	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KU251_19660	COG0671	phosphoesterase, PA-phosphatase related
KU251_19665	COG0861	Integral membrane protein TerC family
KU251_19675	COG0754	glutathionylspermidine amidase activity
KU251_19685	COG0402	S-adenosylhomocysteine deaminase activity
KU251_19700	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KU251_19705	COG1230	cation diffusion facilitator family transporter
KU251_19720	COG0706	membrane insertase activity
KU251_19790	COG1525	nuclease
KU251_19860	COG1475	DNA binding
KU251_19875	COG3853	Toxic anion resistance protein (TelA)
KU251_20055	COG0741	lytic transglycosylase activity
KU251_20090	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KU251_20225	COG4683	PFAM Phage derived protein Gp49-like (DUF891)