locus-tag	class	description
HFD83_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HFD83_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HFD83_00030	ENOG4105DQR	SNARE associated Golgi
HFD83_00035	ENOG4105C5H	ABC transporter
HFD83_00040	ENOG4108821	RND type efflux pump
HFD83_00045	ENOG4108821	RND type efflux pump
HFD83_00050	ENOG4108821	RND type efflux pump
HFD83_00060	ENOG4105D74	hydrolase
HFD83_00065	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HFD83_00070	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HFD83_00115	ENOG4105C8J	)-transporter
HFD83_00125	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HFD83_00155	ENOG4105C2W	permease
HFD83_00165	ENOG4108IG5	Transcriptional regulator
HFD83_00170	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HFD83_00205	ENOG4105F27	Major Facilitator
HFD83_00210	ENOG4105CV8	reductase
HFD83_00215	ENOG4105HEI	LysR family (Transcriptional regulator
HFD83_00235	ENOG4105DQ4	alcohol dehydrogenase
HFD83_00240	ENOG4108R3E	Dna-3-methyladenine glycosylase i
HFD83_00255	ENOG4105CEN	a g-specific adenine glycosylase
HFD83_00275	ENOG4108ZZ3	UPF0260 protein
HFD83_00285	ENOG4105D1H	recombination factor protein RarA
HFD83_00290	ENOG4105S64	Formate nitrite transporter
HFD83_00310	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HFD83_00315	ENOG4108RWI	nicotinamidase
HFD83_00320	ENOG4105C09	Bile acid
HFD83_00325	ENOG4107QI1	Mate efflux family protein
HFD83_00330	ENOG4105EWC	Purine nucleoside phosphorylase
HFD83_00350	ENOG4108RXX	maleylacetoacetate isomerase
HFD83_00360	ENOG4105C85	amino acid
HFD83_00370	ENOG4105CKI	cobalamin synthesis protein
HFD83_00380	ENOG4105CZE	histidine utilization repressor
HFD83_00385	ENOG41090B9	response to stress
HFD83_00400	ENOG4105C85	amino acid
HFD83_00410	ENOG41088SP	formiminoglutamate hydrolase
HFD83_00425	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HFD83_00430	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HFD83_00440	ENOG4108ZAI	phosphatidylglycerophosphatase a
HFD83_00445	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HFD83_00460	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HFD83_00495	ENOG4105KHC	sulfurtransferase
HFD83_00525	ENOG4105BZU	Histidine kinase
HFD83_00530	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HFD83_00545	ENOG4107QJQ	Mate efflux family protein
HFD83_00550	ENOG4105CHM	Aminotransferase
HFD83_00555	ENOG4106BRA	Membrane
HFD83_00570	ENOG4105D9M	gamma-glutamylcysteine synthetase
HFD83_00580	ENOG4105CS6	Rhs element vgr protein
HFD83_00585	ENOG4105K4H	Nlp p60 protein
HFD83_00600	ENOG4105IPS	esterase
HFD83_00605	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HFD83_00610	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
HFD83_00615	ENOG4108Z2U	ureidoglycolate hydrolase
HFD83_00625	ENOG41061H0	Monooxygenase
HFD83_00640	ENOG41084YZ	Hydrolase
HFD83_00670	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HFD83_00675	ENOG4105BZU	Histidine kinase
HFD83_00690	ENOG4105KUZ	arsenate reductase
HFD83_00695	ENOG4105CGK	Exodeoxyribonuclease III
HFD83_00715	ENOG4105D7Z	glutathione synthase
HFD83_00735	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
HFD83_00740	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HFD83_00745	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HFD83_00760	ENOG41063SB	peptidase
HFD83_00765	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HFD83_00770	ENOG4107QSN	dihydrolipoamide acetyltransferase
HFD83_00820	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HFD83_00835	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HFD83_00855	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HFD83_00860	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HFD83_00870	ENOG4105D64	Mechanosensitive ion channel
HFD83_00880	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HFD83_00885	ENOG4108W2Y	isochorismatase
HFD83_00895	ENOG4105D5G	Transposase
HFD83_00900	ENOG4105FBW	Monooxygenase
HFD83_00905	ENOG4108UZX	fmn reductase
HFD83_00920	ENOG4105BZU	Histidine kinase
HFD83_00925	ENOG41062QD	Membrane
HFD83_00930	ENOG4107QN1	sodium solute
HFD83_00940	ENOG4105C94	Transporter
HFD83_00950	ENOG4105BZU	Histidine kinase
HFD83_00960	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HFD83_00965	ENOG4108WUH	Transcriptional regulator, TetR family
HFD83_00970	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HFD83_00980	ENOG4105RA2	Membrane
HFD83_00985	ENOG4105DWF	phosphomethylpyrimidine kinase
HFD83_00995	ENOG4107RDB	Major Facilitator
HFD83_01000	ENOG4108UUM	single-stranded DNA-binding protein
HFD83_01010	ENOG4108UMN	azlc family
HFD83_01020	ENOG4105C85	amino acid
HFD83_01030	ENOG4108JPW	Aminotransferase
HFD83_01035	ENOG4105C26	Dehydrogenase
HFD83_01045	ENOG4105CHJ	isochorismatase hydrolase
HFD83_01050	ENOG4105EUB	pirin domain protein
HFD83_01060	ENOG4105F6A	helicase
HFD83_01070	ENOG4105ECI	YeeC-like protein
HFD83_01075	ENOG4107QJE	Chromosome Partitioning Protein
HFD83_01085	ENOG4105F6A	helicase
HFD83_01095	ENOG4108HWY	Beta-lactamase
HFD83_01125	ENOG4105D94	Major Facilitator Superfamily
HFD83_01130	ENOG4106NZI	LysR family Transcriptional regulator
HFD83_01150	ENOG4105CPC	Aldo Keto reductase
HFD83_01155	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
HFD83_01180	ENOG4105KVH	Transcriptional regulator
HFD83_01185	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
HFD83_01250	ENOG4105CUV	Homoserine Kinase
HFD83_01265	ENOG41061CK	Antibiotic biosynthesis monooxygenase
HFD83_01295	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HFD83_01320	ENOG4108R6G	acetyltransferase
HFD83_01325	ENOG4105CYC	Transferase
HFD83_01335	ENOG4105E0F	Histidine kinase
HFD83_01350	ENOG4105CHH	sulfate transporter
HFD83_01355	ENOG4105PDP	Short chain dehydrogenase
HFD83_01365	ENOG4105C5H	ABC transporter
HFD83_01450	ENOG4108IQI	permease
HFD83_01475	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
HFD83_01490	ENOG4105CJN	penicillin-binding protein
HFD83_01495	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HFD83_01500	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
HFD83_01515	ENOG4105DHI	Methyltransferase
HFD83_01520	ENOG4108JQC	penicillin-binding protein 1A
HFD83_01545	ENOG4105E4G	Type IV pilus
HFD83_01565	ENOG4105CBC	glutamate synthase
HFD83_01570	ENOG4105BZ8	glutamate synthase
HFD83_01580	ENOG4108V0P	LemA family
HFD83_01585	ENOG4105HA9	of methanol dehydrogenase type
HFD83_01605	ENOG4108YSG	O-Antigen polymerase
HFD83_01610	ENOG4108UQY	Iron-storage protein
HFD83_01620	ENOG4105KME	endoribonuclease L-psp
HFD83_01625	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HFD83_01640	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HFD83_01690	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HFD83_01705	ENOG4107IFA	Lipase (EC 3.1.1.3)
HFD83_01710	ENOG4105MGK	May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity)
HFD83_01715	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HFD83_01740	ENOG4108JQ1	Dehydrogenase
HFD83_01745	ENOG4105CQB	FAD linked oxidase domain protein
HFD83_01755	ENOG4105VRH	Antibiotic biosynthesis monooxygenase
HFD83_01760	ENOG4105NF4	modulator of drug activity
HFD83_01770	ENOG4107QF7	multi-drug
HFD83_01775	ENOG4105EM2	membrane
HFD83_01780	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HFD83_01785	ENOG4105IPI	Membrane
HFD83_01790	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
HFD83_01820	ENOG4108IQI	permease
HFD83_01825	ENOG4105D82	Glutamate dehydrogenase
HFD83_01830	ENOG4105C8Y	Acetylornithine aminotransferase
HFD83_01840	ENOG4105C26	Dehydrogenase
HFD83_01925	ENOG4105W87	Cbs domain
HFD83_01930	ENOG41067S9	phage shock protein C, PspC
HFD83_01940	ENOG4105CSU	acyl-Coa dehydrogenase
HFD83_01955	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
HFD83_01970	ENOG4105ECY	inositol monophosphatase
HFD83_01975	ENOG4105C1J	atp-dependent rna helicase
HFD83_01985	ENOG4105DHJ	ABC, transporter
HFD83_01990	ENOG4105CY3	ABC transporter, permease
HFD83_02000	ENOG4105E3I	toluene tolerance
HFD83_02010	ENOG4105D7N	magnesium and cobalt transport protein CorA
HFD83_02015	ENOG4108URH	decarboxylase
HFD83_02025	ENOG4105MJ2	Competence protein
HFD83_02030	ENOG4105CB5	ATP-dependent DNA helicase recG
HFD83_02050	ENOG4105C29	acyl-CoA thioesterase
HFD83_02055	ENOG4105CK2	sodium dicarboxylate symporter
HFD83_02070	ENOG4105KPV	Transcriptional regulator
HFD83_02080	ENOG4105D7A	ATP-binding protein
HFD83_02090	ENOG41089BK	Glutamine amido-transferase
HFD83_02200	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HFD83_02240	ENOG4105C1G	acyl-Coa dehydrogenase
HFD83_02275	ENOG4105VKU	nucleicacid-binding protein
HFD83_02280	ENOG4105DGW	oligopeptidase A
HFD83_02285	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HFD83_02330	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
HFD83_02335	ENOG4108K2B	transcriptional regulator
HFD83_02345	ENOG4107S2Z	UPF0761 membrane protein
HFD83_02350	ENOG4105CS1	NAD(P)H quinone oxidoreductase
HFD83_02380	ENOG4105C9A	Phoh family
HFD83_02390	ENOG4105E4C	Lytic transglycosylase catalytic
HFD83_02420	ENOG4105D6S	protein involved in catabolism of external DNA
HFD83_02425	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
HFD83_02470	ENOG4105C1G	acyl-Coa dehydrogenase
HFD83_02475	ENOG4108RZE	Tetr family transcriptional regulator
HFD83_02490	ENOG4107QX3	carboxylase
HFD83_02495	ENOG4105C1G	acyl-Coa dehydrogenase
HFD83_02515	ENOG4105KB2	stringent starvation protein b
HFD83_02520	ENOG4107MKT	Stringent starvation protein a
HFD83_02525	ENOG4108UJD	30S ribosomal protein S9
HFD83_02535	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HFD83_02540	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HFD83_02545	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HFD83_02565	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HFD83_02575	ENOG4107RZC	phospholipase d
HFD83_02585	ENOG4105UYK	outer membrane protein a
HFD83_02590	ENOG4108KHX	Diguanylate cyclase
HFD83_02625	ENOG4107QN2	dihydrolipoyl dehydrogenase
HFD83_02640	ENOG4107U2T	alpha beta
HFD83_02650	ENOG4105NAU	thioesterase Superfamily protein
HFD83_02680	ENOG4105K9H	YciI-like protein
HFD83_02690	ENOG4105DB7	PHP domain protein
HFD83_02695	ENOG4105FFC	UPF0187 protein
HFD83_02705	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HFD83_02710	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HFD83_02715	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HFD83_02720	ENOG4105VIE	preprotein translocase, subunit YajC
HFD83_02765	ENOG4105BZU	Histidine kinase
HFD83_02770	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HFD83_02775	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HFD83_02790	ENOG4107BJW	polysaccharide deacetylase
HFD83_02800	ENOG4108PQP	glycosyl transferase group 1
HFD83_02840	ENOG4105UGU	tonB-dependent Receptor
HFD83_02860	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
HFD83_02865	ENOG4108K3A	Glutathione S-transferase
HFD83_02870	ENOG4108R4R	Iron-regulated virulence regulatory protein
HFD83_02875	ENOG4105CSU	acyl-Coa dehydrogenase
HFD83_02880	ENOG4105CSU	acyl-Coa dehydrogenase
HFD83_02890	ENOG4105EB3	Histidine kinase
HFD83_02895	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HFD83_02900	ENOG4105CNG	UPF0061 protein
HFD83_02920	ENOG4108WBT	adenosyltransferase
HFD83_02970	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HFD83_02990	ENOG4105D3R	alkyl hydroperoxide reductase
HFD83_03005	ENOG4105CSH	Transporter
HFD83_03010	ENOG4108UT2	hemolysin iii
HFD83_03045	ENOG4105CHU	acetyl-coa acetyltransferase
HFD83_03050	ENOG4108R6W	Transcriptional regulator, ARAC family
HFD83_03060	ENOG4105TW1	Carbohydrate-selective porin OprB
HFD83_03065	ENOG4105DZG	Dehydrogenase
HFD83_03070	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HFD83_03090	ENOG4105CHU	acetyl-coa acetyltransferase
HFD83_03100	ENOG4108WHA	ompa motb domain protein
HFD83_03110	ENOG4105E0Y	RtcB Protein
HFD83_03115	ENOG4108IQI	permease
HFD83_03125	ENOG4105C2W	permease
HFD83_03130	ENOG4105CI3	gtp-binding protein typa
HFD83_03145	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
HFD83_03155	ENOG4108VX5	3-methyladenine DNA glycosylase
HFD83_03160	ENOG4105CHB	tonB-dependent Receptor
HFD83_03175	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HFD83_03190	ENOG4105T95	Thiol disulfide interChange protein
HFD83_03195	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
HFD83_03205	ENOG4105K78	MarR family Transcriptional regulator
HFD83_03210	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HFD83_03215	ENOG4105KWI	UPF0339 protein
HFD83_03240	ENOG4108UNF	response regulator
HFD83_03245	ENOG4105M3Z	response regulator
HFD83_03250	ENOG4108ZGA	chew protein
HFD83_03255	ENOG4105C8Q	Methyl-accepting chemotaxis
HFD83_03260	ENOG4105CBS	Chea signal transduction histidine kinase
HFD83_03275	ENOG4107PEH	Entericidin EcnA/B family
HFD83_03285	ENOG4105WD1	Membrane
HFD83_03290	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
HFD83_03340	ENOG4105EM2	membrane
HFD83_03345	ENOG4105C2C	drug resistance transporter, Bcr CflA
HFD83_03365	ENOG4105BZG	amino acid carrier protein
HFD83_03370	ENOG4105D78	K07001 NTE family protein
HFD83_03375	ENOG4105C7B	Threonine dehydratase
HFD83_03410	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HFD83_03420	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HFD83_03430	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HFD83_03435	ENOG4105VQ7	Rod shape-determining protein MreD
HFD83_03440	ENOG4108Z03	MAF-like protein
HFD83_03445	ENOG4105C03	ribonuclease
HFD83_03455	ENOG4105D8T	Acyltransferase
HFD83_03465	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
HFD83_03475	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
HFD83_03500	ENOG4105CF7	AraC family transcriptional regulator
HFD83_03520	ENOG4105C85	amino acid
HFD83_03525	ENOG4105C7F	AcnD-accessory protein PrpF
HFD83_03530	ENOG4105CTB	Polyprenyl synthetase
HFD83_03535	ENOG4105MSB	protein, conserved in bacteria
HFD83_03550	ENOG4105D78	K07001 NTE family protein
HFD83_03570	ENOG4105DIJ	Phosphoethanolamine transferase
HFD83_03575	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HFD83_03580	ENOG4105DHQ	Histidine kinase
HFD83_03595	ENOG4108M0I	Transcriptional regulator
HFD83_03615	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HFD83_03635	ENOG4105K8R	UPF0145 protein
HFD83_03640	ENOG4105K8R	UPF0145 protein
HFD83_03645	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HFD83_03650	ENOG4105BZS	acriflavin resistance protein
HFD83_03655	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HFD83_03660	ENOG410841Q	phosphoesterase PA-phosphatase related protein
HFD83_03690	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
HFD83_03705	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HFD83_03710	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HFD83_03715	ENOG4105KVH	Transcriptional regulator
HFD83_03725	ENOG4105CUB	amino acid
HFD83_03740	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HFD83_03745	ENOG41084BA	UPF0250 protein
HFD83_03750	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HFD83_03785	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
HFD83_03790	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
HFD83_03800	ENOG4105E33	succinate dehydrogenase
HFD83_03815	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HFD83_03820	ENOG4105C7S	Dehydrogenase
HFD83_03825	ENOG4107QN2	dihydrolipoyl dehydrogenase
HFD83_03835	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HFD83_03845	ENOG4105CKW	Inner membrane protein yedI
HFD83_03850	ENOG4105CGZ	zinc metallopeptidase
HFD83_03855	ENOG4105EEQ	Na H antiporter
HFD83_03890	ENOG4105PNM	synthesis protein
HFD83_03905	ENOG41080TK	Universal stress protein
HFD83_03920	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HFD83_03925	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HFD83_03940	ENOG4105HBR	Rna-binding protein
HFD83_03950	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HFD83_03955	ENOG4105EEI	dihydropteroate synthase
HFD83_04005	ENOG4105CSH	Transporter
HFD83_04010	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HFD83_04015	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HFD83_04030	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HFD83_04050	ENOG41080IJ	Diacylglycerol kinase
HFD83_04060	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
HFD83_04065	ENOG4105BZS	acriflavin resistance protein
HFD83_04080	ENOG4105E4C	Lytic transglycosylase catalytic
HFD83_04100	ENOG4108RRZ	Transcription elongation factor GreB
HFD83_04115	ENOG4105CEY	Amp-dependent synthetase and ligase
HFD83_04155	ENOG4105BZW	Glycerate kinase
HFD83_04160	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
HFD83_04165	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HFD83_04180	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
HFD83_04190	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HFD83_04195	ENOG4105C85	amino acid
HFD83_04205	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HFD83_04215	ENOG4105N14	lysine exporter protein LysE YggA
HFD83_04220	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HFD83_04225	ENOG4105BZJ	Electron transfer flavoprotein
HFD83_04230	ENOG4105C10	Electron transfer flavoprotein
HFD83_04235	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HFD83_04270	ENOG4107KET	secretion protein, HlyD family
HFD83_04305	ENOG4105D60	lipoprotein releasing system transmembrane protein
HFD83_04310	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HFD83_04315	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
HFD83_04325	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HFD83_04330	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
HFD83_04335	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HFD83_04345	ENOG4105C02	permease
HFD83_04395	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HFD83_04400	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
HFD83_04410	ENOG4105M8F	Biopolymer transport protein exbD tolR
HFD83_04415	ENOG4105E02	MotA TolQ exbB proton channel
HFD83_04420	ENOG4107YD3	Thioesterase
HFD83_04425	ENOG4105CH2	amidohydrolase
HFD83_04445	ENOG4108ETH	Formylglycinamide ribotide synthetase
HFD83_04450	ENOG4105C2C	drug resistance transporter, Bcr CflA
HFD83_04460	ENOG4108UKI	Enoyl-CoA hydratase
HFD83_04475	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HFD83_04490	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HFD83_04495	ENOG4107VRB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HFD83_04510	ENOG4107R11	Transcriptional regulator
HFD83_04515	ENOG4108IJ6	ABC transporter
HFD83_04525	ENOG4108I5D	sulfate abc transporter
HFD83_04535	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
HFD83_04540	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
HFD83_04545	ENOG4105HHA	aminodeoxychorismate lyase
HFD83_04560	ENOG4108IYU	L-aspartate oxidase
HFD83_04565	ENOG4105C0H	protease
HFD83_04580	ENOG4105C3F	Signal peptidase i
HFD83_04595	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HFD83_04605	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
HFD83_04610	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
HFD83_04615	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
HFD83_04620	ENOG4105EMU	Dehydrogenase
HFD83_04660	ENOG4105BZU	Histidine kinase
HFD83_04670	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HFD83_04680	ENOG4105DTR	rard protein
HFD83_04715	ENOG4107QS8	(LipO)protein
HFD83_04720	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HFD83_04725	ENOG4105EA8	2-Nitropropane dioxygenase
HFD83_04755	ENOG4107R8N	Glycosyl transferase, family 2
HFD83_04770	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HFD83_04775	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HFD83_04780	ENOG4105CEP	NADH dehydrogenase
HFD83_04785	ENOG4105DZ1	carboxypeptidase
HFD83_04795	ENOG4105E9K	Isocitrate dehydrogenase
HFD83_04800	ENOG4108R99	pseudouridine synthase
HFD83_04825	ENOG4105CBP	Major Facilitator
HFD83_04830	ENOG4105EGI	Transcriptional regulator
HFD83_04835	ENOG4108ETY	sodium dicarboxylate symporter
HFD83_04840	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HFD83_04880	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HFD83_04895	ENOG4105D3G	Pseudouridine synthase
HFD83_04900	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
HFD83_04915	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HFD83_04940	ENOG4108JPW	Aminotransferase
HFD83_04945	ENOG4105DY8	decarboxylase
HFD83_04955	ENOG4105F7P	transcriptional regulator AsnC family
HFD83_04960	ENOG4107RA9	decarboxylase
HFD83_04965	ENOG4105C85	amino acid
HFD83_04970	ENOG4105CVA	phosphate
HFD83_04975	ENOG4105C8U	phosphate abc transporter
HFD83_04985	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HFD83_04990	ENOG4105ERU	peptidase
HFD83_05005	ENOG4107QTF	adenylosuccinate lyase
HFD83_05025	ENOG4108Z0R	Transferase
HFD83_05030	ENOG4105DZ1	carboxypeptidase
HFD83_05050	ENOG4108K5P	(LipO)protein
HFD83_05055	ENOG4105EJC	lysr family transcriptional regulator
HFD83_05060	ENOG4105DAN	ATP-dependent protease
HFD83_05075	ENOG4105DHU	Bile acid
HFD83_05095	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
HFD83_05105	ENOG4105D22	carbon starvation protein
HFD83_05110	ENOG4105VCD	cytoplasmic protein
HFD83_05145	ENOG4108K8K	Transcriptional regulator
HFD83_05160	ENOG4105C26	Dehydrogenase
HFD83_05165	ENOG4105C85	amino acid
HFD83_05170	ENOG4105ETT	transcriptional Regulator, LysR family
HFD83_05175	ENOG4105C94	Transporter
HFD83_05180	ENOG4105C94	Transporter
HFD83_05195	ENOG4107QZF	nitrite reductase NADPH large subunit
HFD83_05200	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HFD83_05230	ENOG41060M8	Pfam:PhdYeFM
HFD83_05235	ENOG4107QNK	)-transporter
HFD83_05240	ENOG4107WEA	mandelate racemase muconate lactonizing
HFD83_05250	ENOG4105J7D	transcriptional regulator
HFD83_05275	ENOG4105C2I	pirin domain protein
HFD83_05285	ENOG4105WWK	YheO domain protein
HFD83_05300	ENOG4105CEY	Amp-dependent synthetase and ligase
HFD83_05315	ENOG4108IPW	abc transporter atp-binding protein
HFD83_05335	ENOG4105C0W	non-ribosomal peptide synthetase
HFD83_05340	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
HFD83_05345	ENOG4105WQI	isochorismatase
HFD83_05360	ENOG4105BZ1	(ABC) transporter
HFD83_05380	ENOG4105E4F	Isochorismate synthase
HFD83_05395	ENOG4105NX3	Membrane
HFD83_05420	ENOG4105EUJ	GTP cyclohydrolase i
HFD83_05430	ENOG4105C7W	Xanthine dehydrogenase
HFD83_05460	ENOG4105CD8	aminopeptidase N
HFD83_05465	ENOG4105DDQ	anthranilate synthase
HFD83_05475	ENOG4105DUX	Transporter
HFD83_05490	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HFD83_05525	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HFD83_05530	ENOG4107QNR	UPF0135 protein
HFD83_05535	ENOG4105C0H	protease
HFD83_05545	ENOG4105C6K	Malic enzyme
HFD83_05550	ENOG4105BZU	Histidine kinase
HFD83_05555	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HFD83_05560	ENOG4105SYT	Methylenetetrahydrofolate reductase
HFD83_05565	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
HFD83_05580	ENOG4107QPN	acyl-Coa dehydrogenase
HFD83_05585	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HFD83_05590	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
HFD83_05600	ENOG4107RNU	major facilitator superfamily MFS_1
HFD83_05610	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HFD83_05615	ENOG4105CE9	30S ribosomal protein S2
HFD83_05655	ENOG4105CVE	Lytic murein transglycosylase
HFD83_05660	ENOG4105CNI	cell division protein FtsW
HFD83_05675	ENOG4105E3A	(ABC) transporter
HFD83_05680	ENOG4105DA5	(ABC) transporter
HFD83_05715	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HFD83_05725	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HFD83_05735	ENOG4105E89	ABC transporter
HFD83_05740	ENOG4105DSP	amino acid AbC transporter
HFD83_05745	ENOG4106YG3	ABC transporter
HFD83_05750	ENOG4108JEH	abc transporter atp-binding protein
HFD83_05760	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HFD83_05765	ENOG4105CFP	Peptidase U32
HFD83_05770	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HFD83_05775	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HFD83_05780	ENOG4105DP0	ferredoxin-NADP reductase
HFD83_05785	ENOG4108R96	Methyltransferase, YaeB family
HFD83_05795	ENOG4107QHF	type ii secretion system protein e
HFD83_05805	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HFD83_05810	ENOG4105DHQ	Histidine kinase
HFD83_05820	ENOG4105M6F	mutator MutT protein
HFD83_05830	ENOG4105BZ4	penicillin-binding protein
HFD83_05835	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HFD83_05840	ENOG4105VUT	cytoplasmic protein
HFD83_05845	ENOG4107QYG	anthranilate phosphoribosyltransferase
HFD83_05850	ENOG4105CK2	sodium dicarboxylate symporter
HFD83_05855	ENOG4105C1G	acyl-Coa dehydrogenase
HFD83_05860	ENOG4105NIV	Esterase
HFD83_05865	ENOG4105CQC	Prephenate dehydratase
HFD83_05870	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HFD83_05880	ENOG4105CIN	aminoacyl-histidine dipeptidase
HFD83_05885	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HFD83_05915	ENOG4105M08	Membrane
HFD83_05920	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HFD83_05930	ENOG4105VEQ	Cold shock protein
HFD83_05935	ENOG4105C1J	atp-dependent rna helicase
HFD83_05945	ENOG41069NU	Nitroreductase
HFD83_06290	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HFD83_06305	ENOG4105C5I	Dehydrogenase
HFD83_06310	ENOG4105ERG	peptidase m48, ste24p
HFD83_06315	ENOG4105KTH	gatB Yqey
HFD83_06345	ENOG4105D9P	serine threonine protein kinase
HFD83_06370	ENOG4105EVZ	LysR family transcriptional regulator
HFD83_06375	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HFD83_06380	ENOG4105C26	Dehydrogenase
HFD83_06415	ENOG4105H4F	exported protein
HFD83_06445	ENOG4105D6U	Sodium Glutamate Symporter
HFD83_06455	ENOG4105JXH	GntR family transcriptional regulator
HFD83_06505	ENOG4105CSH	Transporter
HFD83_06525	ENOG4105CEB	Aspartate aminotransferase
HFD83_06540	ENOG4105F1S	paraquat-inducible protein a
HFD83_06545	ENOG4105DY2	Paraquat-inducible protein b
HFD83_06575	ENOG4108BUD	transposase
HFD83_06590	ENOG4108BUD	transposase
HFD83_06640	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HFD83_06695	ENOG4108BUD	transposase
HFD83_06710	ENOG4105CK2	sodium dicarboxylate symporter
HFD83_06720	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HFD83_06725	ENOG4108UMI	ABC transporter, permease
HFD83_06730	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HFD83_06740	ENOG4105C12	Phosphoribosylglycinamide synthetase
HFD83_06745	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HFD83_06750	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
HFD83_06800	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HFD83_06805	ENOG4105CDU	Replicative dna helicase
HFD83_06830	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
HFD83_06835	ENOG4105CCU	oxidase (Subunit III)
HFD83_06840	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HFD83_06845	ENOG4105E2S	oxidase) subunit II
HFD83_06870	ENOG4107BJW	polysaccharide deacetylase
HFD83_06875	ENOG4105CND	Glycosyl transferase, family 2
HFD83_06890	ENOG4105DEN	Luciferase family
HFD83_06905	ENOG4105CC0	LysR family Transcriptional regulator
HFD83_06920	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HFD83_06925	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HFD83_06930	ENOG4105GVF	(ABC) transporter
HFD83_06945	ENOG4105C1G	acyl-Coa dehydrogenase
HFD83_06955	ENOG4108MEJ	flavin reductase domain protein
HFD83_06960	ENOG4105D06	uba thif-type nad fad binding protein
HFD83_06980	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HFD83_06985	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HFD83_06995	ENOG4105C08	Histidine kinase
HFD83_07000	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
HFD83_07005	ENOG4105CFQ	glutamine synthetase
HFD83_07020	ENOG4107S74	Lysophospholipid transporter LplT
HFD83_07025	ENOG4105CFU	surface antigen
HFD83_07040	ENOG4107QIJ	Aconitate hydratase 2
HFD83_07050	ENOG4105EYW	Ion transport protein
HFD83_07055	ENOG4105F27	Major Facilitator
HFD83_07070	ENOG4105DZ2	Transcriptional regulator
HFD83_07105	ENOG4105K8N	protein family UPF0079, ATPase
HFD83_07110	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HFD83_07120	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HFD83_07125	ENOG4108TZV	Membrane
HFD83_07130	ENOG4108RCM	Nitroreductase
HFD83_07140	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
HFD83_07150	ENOG4105CX6	glutaminyL-tRNA synthetase
HFD83_07155	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HFD83_07160	ENOG4107FQ9	ethanolamine ammonia-lyase
HFD83_07165	ENOG4105CPD	ethanolamine ammonia-lyase
HFD83_07170	ENOG4107R55	ethanolamine transporter
HFD83_07180	ENOG4107RR1	TRANSCRIPTIONal
HFD83_07190	ENOG4105C0A	alcohol dehydrogenase
HFD83_07195	ENOG4107QUV	Domain protein
HFD83_07205	ENOG4105F4I	Transcriptional regulator
HFD83_07225	ENOG4105CD8	aminopeptidase N
HFD83_07235	ENOG4105EMU	Dehydrogenase
HFD83_07245	ENOG4105G7T	Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity)
HFD83_07250	ENOG4105EW9	transcriptional regulator AsnC family
HFD83_07260	ENOG4105R8C	Transcriptional regulator
HFD83_07270	ENOG4105CUY	Mechanosensitive ion channel
HFD83_07305	ENOG4105CNM	Receptor
HFD83_07325	ENOG4105C5H	ABC transporter
HFD83_07330	ENOG41081QV	Universal stress protein
HFD83_07355	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HFD83_07365	ENOG4105DKK	Benzoate
HFD83_07370	ENOG4105EW9	transcriptional regulator AsnC family
HFD83_07375	ENOG4108NIW	Leucine export protein LeuE
HFD83_07385	ENOG4105C5Q	Transcriptional regulator
HFD83_07395	ENOG4105CHU	acetyl-coa acetyltransferase
HFD83_07400	ENOG4105CHR	reductase
HFD83_07425	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HFD83_07430	ENOG4105HSS	phospholipase C
HFD83_07440	ENOG4105C0A	alcohol dehydrogenase
HFD83_07470	ENOG4105CBC	glutamate synthase
HFD83_07490	ENOG4105D8G	Major Facilitator superfamily
HFD83_07500	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HFD83_07505	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HFD83_07530	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HFD83_07540	ENOG4107QZF	nitrite reductase NADPH large subunit
HFD83_07545	ENOG4108IFG	nitrite reductase, (NAD(P)H)
HFD83_07565	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HFD83_07580	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HFD83_07585	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HFD83_07595	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HFD83_07600	ENOG4105T38	integral membrane protein
HFD83_07620	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
HFD83_07625	ENOG4105CMR	udp-glucose 4-epimerase
HFD83_07680	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HFD83_07685	ENOG4105CUX	Signal transduction histidine kinase
HFD83_07705	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HFD83_07710	ENOG4105KNE	Phosphatidate cytidylyltransferase
HFD83_07720	ENOG4105DZP	Membrane-associated zinc metalloprotease
HFD83_07745	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HFD83_07760	ENOG4105Y3E	Modulates RecA activity (By similarity)
HFD83_07770	ENOG4105VEJ	Heat shock protein
HFD83_07775	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
HFD83_07800	ENOG4105F7P	transcriptional regulator AsnC family
HFD83_07810	ENOG4105C85	amino acid
HFD83_07825	ENOG4105CHH	sulfate transporter
HFD83_07830	ENOG4108RAV	Conserved protein
HFD83_07835	ENOG4105D8V	Glucose sorbosone dehydrogenase
HFD83_07845	ENOG4105BZU	Histidine kinase
HFD83_07865	ENOG4105DM4	PTS System
HFD83_07870	ENOG4105DE4	1-phosphofructokinase
HFD83_07875	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HFD83_07900	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
HFD83_07905	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HFD83_07910	ENOG4105CC0	LysR family Transcriptional regulator
HFD83_07920	ENOG4105M2J	Glutaredoxin
HFD83_07925	ENOG4105C8Y	Acetylornithine aminotransferase
HFD83_07930	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HFD83_07955	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HFD83_07965	ENOG41068P6	UPF0319 protein
HFD83_07985	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HFD83_07990	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HFD83_08000	ENOG4105PV3	Inner membrane protein yqiJ
HFD83_08015	ENOG4105E0K	tonB-dependent siderophore receptor
HFD83_08025	ENOG4105HDD	phospholipase
HFD83_08030	ENOG4105CZN	Potassium uptake protein
HFD83_08040	ENOG4105C7B	Threonine dehydratase
HFD83_08070	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HFD83_08075	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HFD83_08085	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HFD83_08100	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HFD83_08145	ENOG4107VMU	Membrane
HFD83_08150	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HFD83_08160	ENOG4107QP7	CoA-transferase subunit A
HFD83_08165	ENOG4107QNJ	CoA-transferase subunit B
HFD83_08170	ENOG4105CHU	acetyl-coa acetyltransferase
HFD83_08175	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
HFD83_08180	ENOG4105F2Z	3-oxoadipate enol-lactonase
HFD83_08185	ENOG4105D2S	major facilitator superfamily
HFD83_08190	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
HFD83_08195	ENOG4105EU7	Protocatechuate 3,4-dioxygenase, beta
HFD83_08200	ENOG4105RM9	Protocatechuate 3,4-dioxygenase alpha
HFD83_08205	ENOG4105FF2	Type I DHQase
HFD83_08210	ENOG4106JPM	3-dehydroshikimate dehydratase
HFD83_08215	ENOG4105TW1	Carbohydrate-selective porin OprB
HFD83_08220	ENOG4105DZG	Dehydrogenase
HFD83_08230	ENOG4105MD1	YeeE YedE family protein
HFD83_08245	ENOG4107HP6	Transcriptional regulator
HFD83_08250	ENOG4108PTX	LysR family Transcriptional regulator
HFD83_08255	ENOG4105C1G	acyl-Coa dehydrogenase
HFD83_08280	ENOG4105DNH	Major Facilitator
HFD83_08290	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HFD83_08310	ENOG4105FUY	alpha subunit
HFD83_08320	ENOG4105CHR	reductase
HFD83_08340	ENOG4105F11	amine oxidase
HFD83_08350	ENOG4105C26	Dehydrogenase
HFD83_08360	ENOG4105F2Z	3-oxoadipate enol-lactonase
HFD83_08365	ENOG4105CHU	acetyl-coa acetyltransferase
HFD83_08370	ENOG4107QNJ	CoA-transferase subunit B
HFD83_08375	ENOG4107QP7	CoA-transferase subunit A
HFD83_08385	ENOG4105NN7	muconolactone delta-isomerase
HFD83_08390	ENOG4105DTQ	mandelate racemase muconate lactonizing
HFD83_08395	ENOG4108KB2	LysR family Transcriptional regulator
HFD83_08405	ENOG4107EJG	GntR family transcriptional regulator
HFD83_08425	ENOG4105CZJ	Aldehyde dehydrogenase
HFD83_08445	ENOG4105C1G	acyl-Coa dehydrogenase
HFD83_08450	ENOG4105CHR	reductase
HFD83_08455	ENOG4108JU7	Transcriptional regulator
HFD83_08465	ENOG41062QD	Membrane
HFD83_08480	ENOG4107RGH	Aldehyde dehydrogenase
HFD83_08495	ENOG4105CH6	catalase
HFD83_08515	ENOG4105K56	Transcriptional regulator
HFD83_08520	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HFD83_08530	ENOG4105NAE	bifunctional deaminase-reductase domain protein
HFD83_08560	ENOG4107Z3H	Transcriptional regulator, TetR family
HFD83_08570	ENOG4105CHJ	isochorismatase hydrolase
HFD83_08575	ENOG4105EJC	lysr family transcriptional regulator
HFD83_08580	ENOG4105D8V	Glucose sorbosone dehydrogenase
HFD83_08585	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HFD83_08595	ENOG4105CH2	amidohydrolase
HFD83_08605	ENOG4105D5K	Hemolysin activator protein
HFD83_08610	ENOG4105CKT	filamentous hemagglutinin
HFD83_08655	ENOG4106P55	Transcriptional regulator
HFD83_08685	ENOG4105JSC	dimethylmenaquinone methyltransferase
HFD83_08705	ENOG4105CW7	secretion protein, HlyD family
HFD83_08720	ENOG4105CZJ	Aldehyde dehydrogenase
HFD83_08735	ENOG4105DDW	LysR family Transcriptional regulator
HFD83_08740	ENOG4105EXW	epimerase dehydratase
HFD83_08750	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HFD83_08755	ENOG4105CF7	AraC family transcriptional regulator
HFD83_08770	ENOG4105DQ4	alcohol dehydrogenase
HFD83_08780	ENOG4105EHG	Permease protein
HFD83_08785	ENOG4105E0A	ABC, transporter
HFD83_08805	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HFD83_08880	ENOG4108UAJ	Transcriptional regulator
HFD83_08920	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HFD83_08970	ENOG4108BAS	reductase
HFD83_08985	ENOG4108R6W	Transcriptional regulator, ARAC family
HFD83_08990	ENOG4108821	RND type efflux pump
HFD83_08995	ENOG4105E0F	Histidine kinase
HFD83_09000	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HFD83_09005	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HFD83_09010	ENOG4105BZS	acriflavin resistance protein
HFD83_09015	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HFD83_09025	ENOG4105CT3	Monooxygenase
HFD83_09045	ENOG4105CJP	fad dependent oxidoreductase
HFD83_09065	ENOG4105X0I	Fimbrial
HFD83_09120	ENOG4107RZC	phospholipase d
HFD83_09140	ENOG4108IGT	Dipeptidase
HFD83_09175	ENOG4107T31	5'-nucleotidase
HFD83_09185	ENOG4105WQI	isochorismatase
HFD83_09190	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
HFD83_09195	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
HFD83_09200	ENOG4105E0C	molybdate abc transporter
HFD83_09205	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HFD83_09210	ENOG4105F4R	Transcriptional regulator mode
HFD83_09215	ENOG4108Q89	anthranilate 1,2-dioxygenase large subunit
HFD83_09220	ENOG4108YS2	small subunit
HFD83_09225	ENOG4105F57	Anthranilate dioxygenase reductase
HFD83_09250	ENOG4105CHR	reductase
HFD83_09260	ENOG4105D2S	major facilitator superfamily
HFD83_09265	ENOG4105CF7	AraC family transcriptional regulator
HFD83_09275	ENOG4105DTD	Dehydrogenase
HFD83_09280	ENOG4105CY2	Citrate transporter
HFD83_09290	ENOG4108M0I	Transcriptional regulator
HFD83_09300	ENOG4107QNJ	CoA-transferase subunit B
HFD83_09305	ENOG4105CRW	Short chain fatty acid transporter
HFD83_09310	ENOG4105CHU	acetyl-coa acetyltransferase
HFD83_09320	ENOG4107YNJ	LysR family Transcriptional regulator
HFD83_09335	ENOG4108IJ0	Aspartate ammonia-lyase
HFD83_09345	ENOG4105CSH	Transporter
HFD83_09365	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HFD83_09370	ENOG4106FTQ	Taurine ABC transporter, periplasmic
HFD83_09395	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HFD83_09400	ENOG4105KVH	Transcriptional regulator
HFD83_09405	ENOG4105UEI	Transcriptional Regulator AraC Family
HFD83_09420	ENOG4108VCT	Sulfite exporter TauE/SafE
HFD83_09430	ENOG4107QPB	Beta-lactamase domain protein
HFD83_09440	ENOG4105FFC	UPF0187 protein
HFD83_09450	ENOG4105CHR	reductase
HFD83_09465	ENOG4105CPP	Dehydrogenase, E1 component
HFD83_09470	ENOG4107R0V	Pyruvate dehydrogenase
HFD83_09475	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HFD83_09490	ENOG4105BZU	Histidine kinase
HFD83_09500	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
HFD83_09505	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HFD83_09550	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HFD83_09565	ENOG4105C28	cystathionine
HFD83_09610	ENOG4105K59	histidine triad (HIT) protein
HFD83_09635	ENOG4107QWP	ABC-2 type transporter
HFD83_09640	ENOG4107QWP	ABC-2 type transporter
HFD83_09645	ENOG4105CJ1	ABC, transporter
HFD83_09660	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HFD83_09665	ENOG4105CNM	Receptor
HFD83_09685	ENOG4107TSN	permease
HFD83_09690	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HFD83_09710	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
HFD83_09715	ENOG4108YZT	Adenosylcobinamide kinase
HFD83_09765	ENOG4105DJU	Siderophore biosynthesis protein
HFD83_09770	ENOG4105DUU	IucA IucC family protein
HFD83_09790	ENOG4108Z66	YbaK ebsC protein
HFD83_09805	ENOG4105C1G	acyl-Coa dehydrogenase
HFD83_09810	ENOG4105C1G	acyl-Coa dehydrogenase
HFD83_09815	ENOG4105EEF	Alkane 1-monooxygenase
HFD83_09820	ENOG4105E7U	AraC family transcriptional regulator
HFD83_09825	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HFD83_09830	ENOG4105K70	DNA-binding protein
HFD83_09845	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HFD83_09855	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
HFD83_09860	ENOG4108Z4V	iron-sulfur cluster assembly
HFD83_09875	ENOG4108ZIT	Ferredoxin, 2FE-2S
HFD83_09880	ENOG4105F8J	Adenylate Guanylate cyclase
HFD83_09890	ENOG4108JA2	transcriptioN-repair coupling factor
HFD83_09910	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
HFD83_09915	ENOG4105K4T	epimerase
HFD83_09930	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HFD83_09950	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HFD83_09960	ENOG4105DGW	oligopeptidase A
HFD83_10000	ENOG4105SG9	biopolymer transport protein, ExbD
HFD83_10010	ENOG4107QP3	malate synthase g
HFD83_10015	ENOG4105D6Z	AFG1 family ATPase
HFD83_10025	ENOG4107RN6	Monooxygenase
HFD83_10045	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HFD83_10050	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HFD83_10065	ENOG4108Z6B	deaminase
HFD83_10085	ENOG4108RTD	type II secretion system protein K
HFD83_10110	ENOG4105F8V	Hydrolase, tatD family
HFD83_10120	ENOG4107QRG	dna polymerase iii
HFD83_10130	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HFD83_10135	ENOG4105BZ1	(ABC) transporter
HFD83_10150	ENOG4105FA0	parb-like partition protein
HFD83_10155	ENOG4107QJE	Chromosome Partitioning Protein
HFD83_10165	ENOG4108S0S	Nucleotidyl transferase
HFD83_10170	ENOG4105EHM	Aminoglycoside phosphotransferase
HFD83_10175	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
HFD83_10180	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HFD83_10185	ENOG4105D2N	Aldolase
HFD83_10205	ENOG4108UHJ	MAF-like protein
HFD83_10210	ENOG4105EZE	Cupin 4 family protein
HFD83_10220	ENOG41080HT	Transcriptional regulator, arsr family
HFD83_10230	ENOG4105XPP	Protein of unknown function (DUF1275)
HFD83_10235	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
HFD83_10240	ENOG4105BZ1	(ABC) transporter
HFD83_10250	ENOG4108ZX5	transcriptional regulator
HFD83_10260	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HFD83_10265	ENOG4105CK7	Sodium proline symporter
HFD83_10270	ENOG4105EW9	transcriptional regulator AsnC family
HFD83_10275	ENOG4105C26	Dehydrogenase
HFD83_10280	ENOG4105YGK	Pfam:UPF0157
HFD83_10295	ENOG4108T58	Mg2 transport protein CorA
HFD83_10305	ENOG4108YYC	ycei family
HFD83_10315	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HFD83_10340	ENOG4108HWY	Beta-lactamase
HFD83_10360	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HFD83_10365	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HFD83_10385	ENOG4105X0I	Fimbrial
HFD83_10390	ENOG4105GQR	Chaperone
HFD83_10415	ENOG4108IPJ	Membrane
HFD83_10425	ENOG4105ETS	cytosine purines uracil thiamine allantoin
HFD83_10435	ENOG4105CC0	LysR family Transcriptional regulator
HFD83_10455	ENOG41067SE	Tetr family transcriptional regulator
HFD83_10470	ENOG4105EW9	transcriptional regulator AsnC family
HFD83_10480	ENOG4105CDA	abc transporter atp-binding protein
HFD83_10485	ENOG4105DRP	amino acid AbC transporter
HFD83_10490	ENOG4105EAD	ABC transporter
HFD83_10505	ENOG4107T8P	acyl-Coa dehydrogenase
HFD83_10520	ENOG4105D01	(LipO)protein
HFD83_10525	ENOG4105D01	(LipO)protein
HFD83_10530	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HFD83_10535	ENOG4108UMI	ABC transporter, permease
HFD83_10540	ENOG4105C3G	gtp-binding protein
HFD83_10565	ENOG4108UMN	azlc family
HFD83_10570	ENOG4105ZED	uncharacterized protein ygaH
HFD83_10600	ENOG4105E7U	AraC family transcriptional regulator
HFD83_10605	ENOG4108V06	Glutathione peroxidase
HFD83_10615	ENOG4105CHM	Aminotransferase
HFD83_10630	ENOG4105C0B	DNA polymerase III (alpha subunit)
HFD83_10655	ENOG4108JU3	Alkyl hydroperoxide reductase
HFD83_10670	ENOG4108KB2	LysR family Transcriptional regulator
HFD83_10675	ENOG4105D6J	arsenicaL-resistance protein
HFD83_10680	ENOG41082YX	Transcriptional regulator, arsr family
HFD83_10695	ENOG4105CPN	adenine deaminase
HFD83_10705	ENOG4105CBN	LysR family transcriptional regulator
HFD83_10715	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
HFD83_10730	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
HFD83_10735	ENOG4108IY8	ABC, transporter
HFD83_10740	ENOG4106FTQ	Taurine ABC transporter, periplasmic
HFD83_10750	ENOG4105C54	Major Facilitator superfamily
HFD83_10775	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HFD83_10780	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HFD83_10790	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HFD83_10795	ENOG4108K70	Transcriptional regulator
HFD83_10810	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HFD83_10815	ENOG4105PSI	phosphoribosyl-dephospho-CoA transferase
HFD83_10830	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
HFD83_10835	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
HFD83_10845	ENOG4105DXI	Major Facilitator superfamily
HFD83_10865	ENOG41067MG	lrgb family
HFD83_10870	ENOG4105VAW	lrga family
HFD83_10875	ENOG4105CMU	LysR family (Transcriptional regulator
HFD83_10880	ENOG4108SHQ	Glutathione S-transferase
HFD83_10885	ENOG4105CYM	Glutathione S-transferase
HFD83_10890	ENOG4105CBN	LysR family transcriptional regulator
HFD83_10895	ENOG4105CHR	reductase
HFD83_10905	ENOG4105D7W	serine acetyltransferase
HFD83_10910	ENOG4105ESN	nucleotide-binding protein
HFD83_10915	ENOG4105C9B	Cysteine desulfurase
HFD83_10925	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
HFD83_10930	ENOG4105EXG	Transcriptional regulator
HFD83_10940	ENOG4105CT1	(ABC) transporter
HFD83_10945	ENOG4107RP9	extracellular solute-binding protein, family 3
HFD83_10950	ENOG4105CDA	abc transporter atp-binding protein
HFD83_10955	ENOG4108HW4	amino acid AbC transporter
HFD83_10960	ENOG4105EAD	ABC transporter
HFD83_10975	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HFD83_10980	ENOG4105BZU	Histidine kinase
HFD83_10990	ENOG4105EW9	transcriptional regulator AsnC family
HFD83_11000	ENOG4105KT5	UmuD protein
HFD83_11020	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HFD83_11070	ENOG4105HEI	LysR family (Transcriptional regulator
HFD83_11090	ENOG4105CEY	Amp-dependent synthetase and ligase
HFD83_11095	ENOG4105R8C	Transcriptional regulator
HFD83_11100	ENOG4105C1G	acyl-Coa dehydrogenase
HFD83_11105	ENOG4107QX3	carboxylase
HFD83_11110	ENOG4105E39	Enoyl-CoA hydratase
HFD83_11125	ENOG4105CC0	LysR family Transcriptional regulator
HFD83_11140	ENOG4105CSU	acyl-Coa dehydrogenase
HFD83_11160	ENOG4107QNJ	CoA-transferase subunit B
HFD83_11165	ENOG4107QP7	CoA-transferase subunit A
HFD83_11170	ENOG4107RGD	Major Facilitator superfamily
HFD83_11175	ENOG4105C1G	acyl-Coa dehydrogenase
HFD83_11180	ENOG4105E39	Enoyl-CoA hydratase
HFD83_11185	ENOG4105CHR	reductase
HFD83_11190	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HFD83_11195	ENOG4105CHU	acetyl-coa acetyltransferase
HFD83_11205	ENOG4105EQ0	Major Facilitator superfamily
HFD83_11210	ENOG4105EA8	2-Nitropropane dioxygenase
HFD83_11215	ENOG4108UKI	Enoyl-CoA hydratase
HFD83_11230	ENOG4105C1G	acyl-Coa dehydrogenase
HFD83_11235	ENOG4107RGD	Major Facilitator superfamily
HFD83_11240	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
HFD83_11245	ENOG4107STF	Involved in phosphonate degradation (By similarity)
HFD83_11255	ENOG4107RCV	ABC transporter, permease
HFD83_11260	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HFD83_11265	ENOG4105C4Y	ABC transporter
HFD83_11275	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
HFD83_11280	ENOG4107HP6	Transcriptional regulator
HFD83_11290	ENOG4105HEI	LysR family (Transcriptional regulator
HFD83_11295	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
HFD83_11300	ENOG4105C26	Dehydrogenase
HFD83_11310	ENOG4105ETS	cytosine purines uracil thiamine allantoin
HFD83_11320	ENOG4105C26	Dehydrogenase
HFD83_11325	ENOG4108M8W	Monooxygenase
HFD83_11330	ENOG4105MXW	flavin reductase domain protein, FMN-binding
HFD83_11335	ENOG4108MXF	Alpha Beta Hydrolase
HFD83_11355	ENOG4105CPW	cytochrome b561
HFD83_11360	ENOG4107VGR	Catalase
HFD83_11395	ENOG4107YAU	phenylacetic acid degradation protein
HFD83_11405	ENOG4105V9J	phenylacetic acid degradation operon negative regulatory protein
HFD83_11410	ENOG4105DZS	Phenylacetate-CoA ligase
HFD83_11415	ENOG4105CHU	acetyl-coa acetyltransferase
HFD83_11420	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HFD83_11425	ENOG4108UKI	Enoyl-CoA hydratase
HFD83_11430	ENOG4105E39	Enoyl-CoA hydratase
HFD83_11435	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HFD83_11440	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
HFD83_11445	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
HFD83_11450	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
HFD83_11455	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
HFD83_11460	ENOG4105DXM	phenylacetic acid degradation protein
HFD83_11465	ENOG4105EJQ	L-serine dehydratase
HFD83_11470	ENOG4107QTZ	amino acid
HFD83_11475	ENOG4105CZJ	Aldehyde dehydrogenase
HFD83_11500	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HFD83_11520	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HFD83_11530	ENOG4108Z4X	TRANSCRIPTIONal
HFD83_11545	ENOG4105WPN	DNA integration recombination invertion protein
HFD83_11560	ENOG4105DJ2	Major Facilitator Superfamily
HFD83_11565	ENOG4107Y2X	deaminase
HFD83_11575	ENOG4105EMY	transcriptional regulator
HFD83_11605	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HFD83_11685	ENOG4108HW3	(ABC) transporter
HFD83_11695	ENOG4105MRR	Transcriptional regulator (By similarity)
HFD83_11715	ENOG4108MXQ	glutathione-regulated potassium-efflux system ancillary protein KefF
HFD83_11720	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HFD83_11735	ENOG4105E2A	Dehydrogenase
HFD83_11745	ENOG4105R8C	Transcriptional regulator
HFD83_11765	ENOG4107R4J	Chloride channel
HFD83_11770	ENOG4108JIK	carboxylase
HFD83_11790	ENOG4105C5A	transporter
HFD83_11795	ENOG4108WAV	Transcriptional regulator
HFD83_11810	ENOG4105CNA	YD repeat protein
HFD83_11850	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
HFD83_11870	ENOG4105D2S	major facilitator superfamily
HFD83_11880	ENOG4105D1S	lipid A biosynthesis
HFD83_11885	ENOG4105BZU	Histidine kinase
HFD83_11890	ENOG4107AQZ	Membrane
HFD83_11910	ENOG4108Z4U	Ferredoxin
HFD83_11950	ENOG4105DFG	type I secretion outer membrane protein
HFD83_11960	ENOG4108IUZ	ABC transporter
HFD83_11965	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
HFD83_11980	ENOG4105C2X	Arabinose 5-phosphate isomerase
HFD83_12045	ENOG4105II7	pyrroline-5-carboxylate reductase
HFD83_12055	ENOG4105VEQ	Cold shock protein
HFD83_12060	ENOG410829K	Lysine exporter protein (Lyse ygga)
HFD83_12095	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HFD83_12145	ENOG4108KB2	LysR family Transcriptional regulator
HFD83_12150	ENOG4105FUY	alpha subunit
HFD83_12155	ENOG4108UKV	benzoate 1,2-dioxygenase
HFD83_12160	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
HFD83_12165	ENOG4107SEV	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
HFD83_12170	ENOG4105DKK	Benzoate
HFD83_12175	ENOG4105D2S	major facilitator superfamily
HFD83_12190	ENOG4105CQ7	ATP-dependent helicase
HFD83_12195	ENOG4105D3R	alkyl hydroperoxide reductase
HFD83_12205	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HFD83_12215	ENOG4108JU3	Alkyl hydroperoxide reductase
HFD83_12225	ENOG4108K3A	Glutathione S-transferase
HFD83_12235	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HFD83_12240	ENOG4108TGY	Glutathione S-transferase
HFD83_12250	ENOG4108ZG0	Ompa motb domain protein
HFD83_12255	ENOG4105CD3	dihydroorotase
HFD83_12285	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HFD83_12300	ENOG4108UKZ	OsmC family
HFD83_12305	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
HFD83_12315	ENOG4105CPC	Aldo Keto reductase
HFD83_12330	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HFD83_12340	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HFD83_12350	ENOG4105CFH	Aspartokinase
HFD83_12360	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HFD83_12370	ENOG4105CPW	cytochrome b561
HFD83_12375	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HFD83_12380	ENOG4105C7N	Xanthine uracil vitamin C permease
HFD83_12390	ENOG4105F95	Monooxygenase
HFD83_12430	ENOG4108BUD	transposase
HFD83_12440	ENOG4108BUD	transposase
HFD83_12505	ENOG4108BUD	transposase
HFD83_12520	ENOG4108BUD	transposase
HFD83_12525	ENOG4108C33	Resolvase
HFD83_12535	ENOG4108BUD	transposase
HFD83_12550	ENOG4108BUD	transposase
HFD83_12575	ENOG4105C26	Dehydrogenase
HFD83_12595	ENOG4105CUB	amino acid
HFD83_12605	ENOG4105C85	amino acid
HFD83_12645	ENOG4105CNA	YD repeat protein
HFD83_12670	ENOG4105D01	(LipO)protein
HFD83_12675	ENOG4108M3P	Membrane
HFD83_12690	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HFD83_12710	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
HFD83_12730	ENOG4108JQ5	ABC transporter
HFD83_12735	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
HFD83_12740	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
HFD83_12750	ENOG4105E9H	Lytic Murein transglycosylase
HFD83_12750	ENOG4105E9H	Lytic Murein transglycosylase
HFD83_12755	ENOG4107RZZ	dna polymerase iii epsilon subunit
HFD83_12765	ENOG4105E09	nadh pyrophosphatase
HFD83_12775	ENOG4105W4M	Transport-associated protein
HFD83_12785	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HFD83_12795	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
HFD83_12800	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
HFD83_12820	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HFD83_12825	ENOG4105D0A	hydroxylase
HFD83_12830	ENOG4107RAQ	aminopeptidase
HFD83_12915	ENOG4105E4C	Lytic transglycosylase catalytic
HFD83_12975	ENOG4105EFC	phage portal protein HK97 family
HFD83_13070	ENOG4105CDU	Replicative dna helicase
HFD83_13085	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HFD83_13135	ENOG4105DIJ	Phosphoethanolamine transferase
HFD83_13180	ENOG4105DR5	peptidase
HFD83_13505	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HFD83_13530	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
HFD83_13540	ENOG4105D82	Glutamate dehydrogenase
HFD83_13545	ENOG4108R3D	Electron transport complex
HFD83_13550	ENOG4105CSM	endonuclease III
HFD83_13575	ENOG4105CJN	penicillin-binding protein
HFD83_13580	ENOG4106H78	methyltransferase
HFD83_13595	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HFD83_13605	ENOG4105CQM	Urea amidohydrolase subunit alpha
HFD83_13635	ENOG4107RET	Isocitrate lyase
HFD83_13645	ENOG4105C37	(CBS) domain
HFD83_13650	ENOG4105D4T	Citrate transporter
HFD83_13665	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
HFD83_13680	ENOG4108MRJ	
HFD83_13700	ENOG4105VCQ	rubredoxin
HFD83_13705	ENOG4107QZF	nitrite reductase NADPH large subunit
HFD83_13715	ENOG4105C5Q	Transcriptional regulator
HFD83_13735	ENOG4107U91	Rhomboid family
HFD83_13740	ENOG4105CV6	ABC transporter, permease
HFD83_13745	ENOG4108I0Y	(ABC) transporter
HFD83_13750	ENOG4108UJV	acyl-CoA thioesterase i
HFD83_13770	ENOG4107RNH	Outer membrane receptor FepA
HFD83_13785	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
HFD83_13790	ENOG4105E6M	Sulphatase-modifying factor protein
HFD83_13810	ENOG4105CJ3	phosphate transporter
HFD83_13815	ENOG4105C3R	Methionine synthase
HFD83_13830	ENOG4105CSP	Major Facilitator Superfamily
HFD83_13840	ENOG4108PZW	LysR family Transcriptional regulator
HFD83_13850	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HFD83_13855	ENOG4105EU0	Major facilitator Superfamily
HFD83_13860	ENOG4108R6W	Transcriptional regulator, ARAC family
HFD83_13865	ENOG4105CSV	Glutaminase
HFD83_13870	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HFD83_13875	ENOG4105CSH	Transporter
HFD83_13885	ENOG4105C7K	acetolactate synthase
HFD83_13900	ENOG4105CHR	reductase
HFD83_13905	ENOG4108MXF	Alpha Beta Hydrolase
HFD83_13915	ENOG4105DJB	Major Facilitator Superfamily
HFD83_13920	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
HFD83_13930	ENOG4105CHR	reductase
HFD83_13950	ENOG41069M3	Transcriptional regulator
HFD83_13965	ENOG4106YT9	Enoyl-CoA hydratase
HFD83_13975	ENOG4105CND	Glycosyl transferase, family 2
HFD83_13980	ENOG4107BJW	polysaccharide deacetylase
HFD83_13990	ENOG4108VWS	Yaeq family
HFD83_14000	ENOG4105CKI	cobalamin synthesis protein
HFD83_14010	ENOG4108S4H	thioesterase Superfamily protein
HFD83_14020	ENOG4105C94	Transporter
HFD83_14025	ENOG4105C94	Transporter
HFD83_14030	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
HFD83_14055	ENOG4107QK5	Homocysteine s-methyltransferase
HFD83_14060	ENOG4105D5Q	Arginine ornithine antiporter
HFD83_14085	ENOG4108YNN	Heme oxygenase
HFD83_14115	ENOG4108SF5	RNA Polymerase
HFD83_14125	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HFD83_14130	ENOG4105C54	Major Facilitator superfamily
HFD83_14150	ENOG4105F8V	Hydrolase, tatD family
HFD83_14185	ENOG4108UUM	single-stranded DNA-binding protein
HFD83_14240	ENOG4105DFP	Integrase
HFD83_14260	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HFD83_14345	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HFD83_14385	ENOG4105K4U	addiction module toxin, RelE StbE family
HFD83_14695	ENOG41083X2	DNA polymerase III, epsilon subunit
HFD83_14730	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HFD83_14735	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HFD83_14740	ENOG4105CW7	secretion protein, HlyD family
HFD83_14745	ENOG4108VUY	thioesterase Superfamily protein
HFD83_14750	ENOG4105D52	delta-aminolevulinic acid dehydratase
HFD83_14755	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HFD83_14760	ENOG4105ECP	epimerase
HFD83_14780	ENOG4107RH8	nuclease SbcCD subunit D
HFD83_14785	ENOG4105EYH	Exonuclease
HFD83_14790	ENOG4105DFA	alanine racemase domain protein
HFD83_14795	ENOG4105CZX	twitching motility protein
HFD83_14800	ENOG4105CZX	twitching motility protein
HFD83_14805	ENOG41090R7	Ferric uptake
HFD83_14830	ENOG4105E7A	Glutamine amidotransferase
HFD83_14845	ENOG4107QKV	phosphomannomutase
HFD83_14855	ENOG4105C4R	Atp-dependent dna helicase
HFD83_14860	ENOG4108ZG0	Ompa motb domain protein
HFD83_14865	ENOG4106HNH	Acyl-transferase
HFD83_14880	ENOG4107QMS	site-determining protein
HFD83_14900	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
HFD83_14905	ENOG4105CNU	cell division protein FtsK
HFD83_14910	ENOG4105C3M	thioredoxin reductase
HFD83_14915	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HFD83_14925	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
HFD83_14970	ENOG4108YXA	Membrane
HFD83_14975	ENOG4105EUB	pirin domain protein
HFD83_14985	ENOG4105C4K	Nad synthetase
HFD83_15000	ENOG4105E3J	oxidoreductase
HFD83_15005	ENOG4105C26	Dehydrogenase
HFD83_15010	ENOG4105DVW	rieske (2Fe-2S)
HFD83_15020	ENOG4105C94	Transporter
HFD83_15025	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HFD83_15030	ENOG4105EJC	lysr family transcriptional regulator
HFD83_15050	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HFD83_15070	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HFD83_15075	ENOG4105C34	Pseudouridine synthase
HFD83_15080	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HFD83_15085	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HFD83_15100	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
HFD83_15130	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HFD83_15160	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HFD83_15170	ENOG4105DWF	phosphomethylpyrimidine kinase
HFD83_15180	ENOG4109066	lysm domain bon superfamily protein
HFD83_15190	ENOG4105CHR	reductase
HFD83_15195	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HFD83_15205	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
HFD83_15210	ENOG4108BPE	-transporting atpase
HFD83_15215	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HFD83_15220	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
HFD83_15225	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HFD83_15230	ENOG4105FE9	pseudouridine synthase
HFD83_15240	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HFD83_15245	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HFD83_15255	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HFD83_15260	ENOG4108K4C	ec 3.1.3.12
HFD83_15265	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
HFD83_15270	ENOG4106UW1	Major Facilitator superfamily
HFD83_15290	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HFD83_15300	ENOG4105HF0	Membrane
HFD83_15315	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HFD83_15325	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
HFD83_15375	ENOG4105D1F	ATP-binding protein
HFD83_15385	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HFD83_15415	ENOG4105K6H	D-cysteine desulfhydrase
HFD83_15420	ENOG4105CBX	hi0933 family
HFD83_15445	ENOG4105DP0	ferredoxin-NADP reductase
HFD83_15450	ENOG4105DUM	transcriptional regulator, lysR family
HFD83_15470	ENOG4105C8S	subunit m
HFD83_15475	ENOG4105D65	subunit l
HFD83_15485	ENOG4107UFS	subunit j
HFD83_15500	ENOG4108IEH	NADH dehydrogenase subunit g
HFD83_15505	ENOG4107QIZ	NADH dehydrogenase
HFD83_15510	ENOG4105GKE	subunit e
HFD83_15530	ENOG4105BZU	Histidine kinase
HFD83_15540	ENOG4105E0F	Histidine kinase
HFD83_15545	ENOG4107EXC	regulatoR
HFD83_15555	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HFD83_15565	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HFD83_15575	ENOG4105EB3	Histidine kinase
HFD83_15645	ENOG4105DZG	Dehydrogenase
HFD83_15665	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HFD83_15685	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
HFD83_15700	ENOG4105ETT	transcriptional Regulator, LysR family
HFD83_15720	ENOG4105CH2	amidohydrolase
HFD83_15730	ENOG4106P55	Transcriptional regulator
HFD83_15745	ENOG4106P55	Transcriptional regulator
HFD83_15750	ENOG4107EFR	Flavocytochrome c
HFD83_15760	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HFD83_15765	ENOG4107RGD	Major Facilitator superfamily
HFD83_15770	ENOG4105C1G	acyl-Coa dehydrogenase
HFD83_15775	ENOG4105ETT	transcriptional Regulator, LysR family
HFD83_15810	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
HFD83_15815	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
HFD83_15820	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HFD83_15835	ENOG4105VR0	copper resistance
HFD83_15840	ENOG4105E3B	Multicopper oxidase
HFD83_15850	ENOG4108HCJ	Hydrolase
HFD83_15855	ENOG4105DJV	ribulose-phosphate 3-epimerase
HFD83_15880	ENOG41072GX	Peptidase M22 Glycoprotease
HFD83_15885	ENOG4108Z0R	Transferase
HFD83_15930	ENOG4105CRQ	synthase (Component I)
HFD83_15940	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HFD83_15945	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HFD83_15950	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HFD83_16020	ENOG4105K56	Transcriptional regulator
HFD83_16025	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HFD83_16030	ENOG4107QHF	type ii secretion system protein e
HFD83_16050	ENOG4105C2M	dna polymerase I
HFD83_16055	ENOG4108VIA	integral membrane protein
HFD83_16060	ENOG4105II7	pyrroline-5-carboxylate reductase
HFD83_16065	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HFD83_16075	ENOG4105C9X	ppx gppa phosphatase
HFD83_16085	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HFD83_16105	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HFD83_16145	ENOG4105W39	Membrane
HFD83_16150	ENOG4105CYM	Glutathione S-transferase
HFD83_16165	ENOG4105CEY	Amp-dependent synthetase and ligase
HFD83_16170	ENOG4105N42	UPF0307 protein
HFD83_16175	ENOG41080Z8	PHOSPHOCARRIER protein
HFD83_16195	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HFD83_16200	ENOG4105DJ0	Poly(A) Polymerase
HFD83_16205	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
HFD83_16210	ENOG4105DXN	mazG family
HFD83_16220	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HFD83_16235	ENOG4105C6T	cysteine synthase
HFD83_16240	ENOG4105BZU	Histidine kinase
HFD83_16245	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
HFD83_16250	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HFD83_16255	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
HFD83_16270	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HFD83_16275	ENOG4105W8H	transhydrogenase (subunit alpha
HFD83_16280	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HFD83_16285	ENOG4106UX7	integral membrane protein
HFD83_16300	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HFD83_16310	ENOG4107RSM	transcriptional regulator
HFD83_16320	ENOG4105CUZ	uba thif-type nad fad binding protein
HFD83_16330	ENOG4107QM5	aconitate hydratase
HFD83_16335	ENOG4105F8V	Hydrolase, tatD family
HFD83_16350	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HFD83_16370	ENOG4105BZU	Histidine kinase
HFD83_16380	ENOG4108ZP8	Acetolactate synthase small subunit
HFD83_16385	ENOG4105C7K	acetolactate synthase
HFD83_16410	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HFD83_16415	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HFD83_16420	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HFD83_16425	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HFD83_16435	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
HFD83_16440	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HFD83_16450	ENOG4105VW4	glutaredoxin 3
HFD83_16470	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HFD83_16475	ENOG4105C2D	reductase
HFD83_16485	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HFD83_16515	ENOG4105C84	Histidine ammonia-lyase
HFD83_16530	ENOG4105CEY	Amp-dependent synthetase and ligase
HFD83_16545	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HFD83_16565	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HFD83_16585	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
HFD83_16605	ENOG4105WVQ	Fe-S assembly protein IscX
HFD83_16620	ENOG4105CN1	protease
HFD83_16635	ENOG4106HB6	Alpha beta hydrolase
HFD83_16645	ENOG4105C26	Dehydrogenase
HFD83_16650	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HFD83_16655	ENOG4105C6Z	Gluconate
HFD83_16660	ENOG4108UHU	Aldolase
HFD83_16665	ENOG4105C01	Dihydroxy-acid dehydratase
HFD83_16670	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HFD83_16675	ENOG4108DNC	Involved in acetate metabolism (By similarity)
HFD83_16680	ENOG4107GFK	fumarate
HFD83_16700	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HFD83_16710	ENOG4108ESX	Receptor
HFD83_16720	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HFD83_16730	ENOG4105DWV	Homoserine O-trans-acetylase
HFD83_16830	ENOG4105CIY	formyltetrahydrofolate deformylase
HFD83_16840	ENOG4107RGH	Aldehyde dehydrogenase
HFD83_16855	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HFD83_16875	ENOG4105VFU	Rna-binding protein
HFD83_16880	ENOG4105C4R	Atp-dependent dna helicase
HFD83_16895	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HFD83_16905	ENOG4105KVH	Transcriptional regulator
HFD83_16920	ENOG4105C5H	ABC transporter
HFD83_16925	ENOG4105N14	lysine exporter protein LysE YggA
HFD83_16930	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
HFD83_16940	ENOG4105CK2	sodium dicarboxylate symporter
HFD83_16995	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HFD83_17020	ENOG4105DUM	transcriptional regulator, lysR family
HFD83_17045	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
HFD83_17060	ENOG4108W5M	transcriptional regulator
HFD83_17075	ENOG4105D29	Helix-turn-helix type 11 domain protein
HFD83_17080	ENOG4107XGZ	Hydrolase
HFD83_17085	ENOG4105EI2	Pseudouridine synthase
HFD83_17095	ENOG4105C03	ribonuclease
HFD83_17100	ENOG4105J5T	Amp-dependent synthetase and ligase
HFD83_17115	ENOG4105CBN	LysR family transcriptional regulator
HFD83_17120	ENOG4105EMU	Dehydrogenase
HFD83_17125	ENOG4105CSA	Coproporphyrinogen iii oxidase
HFD83_17135	ENOG4107QI1	Mate efflux family protein
HFD83_17145	ENOG4107T8P	acyl-Coa dehydrogenase
HFD83_17190	ENOG4108BEW	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
HFD83_17195	ENOG4105C5X	domain protein
HFD83_17210	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HFD83_17220	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
HFD83_17225	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
HFD83_17230	ENOG4108JU5	Magnesium and cobalt efflux protein
HFD83_17235	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HFD83_17240	ENOG4108Z7R	Chaperone CsaA
HFD83_17250	ENOG4108VAU	general secretion pathway protein G
HFD83_17255	ENOG4105D7Q	type ii secretion system
HFD83_17260	ENOG4105C25	Primosomal protein n'
HFD83_17265	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HFD83_17270	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
HFD83_17280	ENOG4105DVC	DnaJ domain protein
HFD83_17285	ENOG4108ZKH	Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity)
HFD83_17290	ENOG4107QUT	magnesium and cobalt transport protein CorA
HFD83_17310	ENOG4107QYX	exodeoxyribonuclease v alpha
HFD83_17315	ENOG4107QKA	exodeoxyribonuclease V beta
HFD83_17320	ENOG4105DSY	exodeoxyribonuclease V, gamma
HFD83_17330	ENOG4105CSR	polyphosphate kinase 2
HFD83_17340	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HFD83_17355	ENOG41061H0	Monooxygenase
HFD83_17360	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HFD83_17375	ENOG4105D65	subunit l
HFD83_17380	ENOG4108ZE9	Monovalent cation H antiporter subunit C
HFD83_17385	ENOG4107R4Z	monovalent cation h antiporter subunit d
HFD83_17390	ENOG4105SC1	monovalent cation H antiporter subunit E
HFD83_17395	ENOG4105W4C	monovalent cation H antiporter subunit F
HFD83_17400	ENOG4105KJM	monovalent cation h antiporter subunit g
HFD83_17415	ENOG4105CHV	Transcription elongation factor NusA
HFD83_17440	ENOG4107EJC	Preprotein translocase subunit SecG
HFD83_17450	ENOG4107QHF	type ii secretion system protein e
HFD83_17465	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HFD83_17475	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HFD83_17490	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HFD83_17500	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HFD83_17530	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HFD83_17535	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HFD83_17600	ENOG4107ZXU	DSBA oxidoreductase
HFD83_17615	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HFD83_17630	ENOG4105D3Y	Na H antiporter
HFD83_17635	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
HFD83_17685	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HFD83_17690	ENOG4105PM1	preprotein translocase subunit SecE
HFD83_17730	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HFD83_17735	ENOG4105TV9	FHA Domain-Containing protein
HFD83_17740	ENOG4105GVR	general secretion pathway protein D
HFD83_17755	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
HFD83_17780	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HFD83_17785	ENOG4108NEV	two component transcriptional regulator, LytTR family
HFD83_17790	ENOG4108HRK	Histidine kinase
HFD83_17805	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HFD83_17810	ENOG4105DFG	type I secretion outer membrane protein
HFD83_17815	ENOG4108RNG	Permease of the drug metabolite transporter
HFD83_17840	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HFD83_17850	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
HFD83_17855	ENOG4105CNI	cell division protein FtsW
HFD83_17870	ENOG4105CE1	Ferrous iron transport protein b
HFD83_17880	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HFD83_17885	ENOG4105T95	Thiol disulfide interChange protein
HFD83_17890	ENOG4105D6E	homoserine dehydrogenase
HFD83_17900	ENOG41061WM	D-Alanyl-D-Alanine
HFD83_17910	ENOG4107TUY	Histidine kinase
HFD83_17915	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HFD83_17920	ENOG4105CN1	protease
HFD83_17925	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HFD83_17930	ENOG4108K5H	permease YjgP YjgQ family protein
HFD83_17970	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HFD83_17980	ENOG4105BZU	Histidine kinase
HFD83_17995	ENOG4105C0P	Mg chelatase subunit ChlI
HFD83_18005	ENOG4108R0M	Aminoglycoside
HFD83_18065	ENOG4105CHH	sulfate transporter
HFD83_18110	ENOG4105C0P	Mg chelatase subunit ChlI
HFD83_18115	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HFD83_18125	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HFD83_18135	ENOG4105EPF	Outer membrane porin
HFD83_18140	ENOG4105F0N	pyrophosphate phospho-hydrolase
HFD83_18155	ENOG4105CEY	Amp-dependent synthetase and ligase
HFD83_18160	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HFD83_18165	ENOG41079KZ	Major Facilitator Superfamily
HFD83_18170	ENOG4105EN6	Membrane
HFD83_18180	ENOG4105EE5	Membrane protein terC
HFD83_18185	ENOG4108URH	decarboxylase
HFD83_18200	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HFD83_18215	ENOG4105CCT	upf0313 protein
HFD83_18235	ENOG4105CS1	NAD(P)H quinone oxidoreductase
HFD83_18245	ENOG4105C6T	cysteine synthase
HFD83_18280	ENOG4105Y7M	Transcriptional regulator, TetR family
HFD83_18315	ENOG4105C79	DNA protecting protein DprA
HFD83_18330	ENOG4108IND	Tetr family transcriptional regulator
HFD83_18335	ENOG4107RTG	Major Facilitator superfamily
HFD83_18345	ENOG4108V06	Glutathione peroxidase
HFD83_18410	ENOG4105FDK	ABC transporter
HFD83_18415	ENOG4105FAV	ABC, transporter
HFD83_18420	ENOG410829K	Lysine exporter protein (Lyse ygga)
HFD83_18425	ENOG4105EZR	dyp-type peroxidase family protein
HFD83_18435	ENOG4107R1I	NAD-dependent malic enzyme
HFD83_18460	ENOG4105EUB	pirin domain protein
HFD83_18480	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HFD83_18485	ENOG4106MP8	UPF0754 membrane protein
HFD83_18490	ENOG4108VBZ	doxx family
HFD83_18495	ENOG4105DQR	SNARE associated Golgi
HFD83_18510	ENOG4107QJE	Chromosome Partitioning Protein
HFD83_18520	ENOG4107PSF	BolA-like protein
HFD83_18540	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
HFD83_18565	ENOG4105C1G	acyl-Coa dehydrogenase
HFD83_18590	ENOG4105CSH	Transporter
HFD83_18595	ENOG4105E39	Enoyl-CoA hydratase
HFD83_18600	ENOG4105E39	Enoyl-CoA hydratase
HFD83_18605	ENOG4105C1G	acyl-Coa dehydrogenase
HFD83_18615	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HFD83_18620	ENOG4105C26	Dehydrogenase
HFD83_18630	ENOG4105C85	amino acid
HFD83_18635	ENOG4105C85	amino acid
HFD83_18640	ENOG4105M4H	endoribonuclease L-psp
HFD83_18655	ENOG4105EW9	transcriptional regulator AsnC family
HFD83_18680	ENOG4105D3G	Pseudouridine synthase
HFD83_18695	ENOG4108IG5	Transcriptional regulator
HFD83_18740	ENOG4108I0Z	Aconitate hydratase
HFD83_18745	ENOG4105BZN	citrate synthase
HFD83_18750	ENOG4105CR4	methylisocitrate lyase
HFD83_18755	ENOG4105DRR	Transcriptional regulator, GntR family
HFD83_18765	ENOG4105CGF	Aromatic amino acid aminotransferase
HFD83_18770	ENOG4105CXG	d-lactate dehydrogenase
HFD83_18780	ENOG41073TP	transcriptional regulator
HFD83_18785	ENOG4105DAA	L-lactate
HFD83_18790	ENOG4107QKV	phosphomannomutase
HFD83_18800	ENOG4105CMR	udp-glucose 4-epimerase
HFD83_18810	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HFD83_18815	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HFD83_18820	ENOG4105D3Q	Sugar transferase
HFD83_18825	ENOG4108RYC	glycosyltransferase
HFD83_18830	ENOG4105CG5	Glycosyl transferase (Group 1
HFD83_18850	ENOG4105CPK	Glycosyl transferase (Group 1
HFD83_18860	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HFD83_18865	ENOG4105J5G	Transferase hexapeptide repeat containing protein
HFD83_18870	ENOG4107R5Z	Oxidoreductase domain protein
HFD83_18875	ENOG4107QQG	Dehydrogenase
HFD83_18880	ENOG4105DAY	polysaccharide export protein
HFD83_18890	ENOG4105D75	Capsular exopolysaccharide family
HFD83_18895	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HFD83_18900	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HFD83_18905	ENOG4105CJR	Integral membrane protein (MviN
HFD83_18910	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
HFD83_18915	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HFD83_18925	ENOG4105HSS	phospholipase C
HFD83_18950	ENOG41062JF	Transcriptional regulator
HFD83_18955	ENOG4108Z33	Thiol disulfide Interchange Protein
HFD83_18965	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HFD83_18970	ENOG4105UBK	short-chain dehydrogenase reductase
HFD83_18985	ENOG4107QZM	n-acetylglutamate synthase
HFD83_18990	ENOG4105GVF	(ABC) transporter
HFD83_18995	ENOG4105GVF	(ABC) transporter
HFD83_19000	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
HFD83_19005	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HFD83_19010	ENOG4108VM9	ABC, transporter
HFD83_19015	ENOG4108R86	Transcriptional regulator
HFD83_19020	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
HFD83_19030	ENOG4105DTN	riboflavin biosynthesis protein ribF
HFD83_19035	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HFD83_19045	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
HFD83_19085	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HFD83_19140	ENOG4105CVE	Lytic murein transglycosylase
HFD83_19145	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HFD83_19150	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HFD83_19160	ENOG4105DFU	Cell wall formation (By similarity)
HFD83_19170	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
HFD83_19175	ENOG4105DU1	integral membrane protein, terc
HFD83_19185	ENOG4106032	Glutathionylspermidine synthase
HFD83_19195	ENOG4107QUY	Guanine deaminase
HFD83_19200	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HFD83_19210	ENOG4105T95	Thiol disulfide interChange protein
HFD83_19215	ENOG4105PGM	cation diffusion facilitator family transporter
HFD83_19230	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFD83_19300	ENOG4105KK6	nuclease
HFD83_19305	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
HFD83_19365	ENOG4105FA0	parb-like partition protein
HFD83_19380	ENOG4105CDW	Resistance protein
HFD83_19515	ENOG4105D5G	Transposase
HFD83_19565	ENOG4105K5T	PilT protein
HFD83_19600	ENOG4105T95	Thiol disulfide interChange protein
HFD83_19730	ENOG4105UGU	tonB-dependent Receptor