locus-tag	class	description
HFD83_00010	COG0592	DNA-directed DNA polymerase activity
HFD83_00020	COG0187	DNA topoisomerase II activity
HFD83_00030	COG0586	Pfam SNARE associated Golgi protein
HFD83_00035	COG0488	(ABC) transporter
HFD83_00060	COG0596	Alpha beta hydrolase
HFD83_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HFD83_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HFD83_00115	COG0733	neurotransmitter:sodium symporter activity
HFD83_00155	COG2233	PERMEase
HFD83_00170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HFD83_00205	COG2814	Major facilitator Superfamily
HFD83_00210	COG0656	L-ascorbic acid biosynthetic process
HFD83_00215	COG0583	DNA-binding transcription factor activity
HFD83_00230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HFD83_00235	COG1064	alcohol dehydrogenase
HFD83_00240	COG2818	Glycosylase
HFD83_00255	COG1194	a g-specific adenine glycosylase
HFD83_00275	COG2983	Belongs to the UPF0260 family
HFD83_00280	COG2133	pyrroloquinoline quinone binding
HFD83_00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HFD83_00290	COG2116	formate transmembrane transporter activity
HFD83_00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HFD83_00315	COG1335	isochorismatase
HFD83_00320	COG0385	Bile acid
HFD83_00325	COG0534	Mate efflux family protein
HFD83_00330	COG1683	Conserved Protein
HFD83_00350	COG0625	glutathione transferase activity
HFD83_00360	COG1113	amino acid transport
HFD83_00370	COG0523	cobalamin synthesis protein
HFD83_00380	COG2188	Transcriptional regulator
HFD83_00410	COG0010	Belongs to the arginase family
HFD83_00425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HFD83_00430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HFD83_00440	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HFD83_00445	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HFD83_00545	COG0534	Mate efflux family protein
HFD83_00550	COG0436	Aminotransferase
HFD83_00555	COG2733	membrane
HFD83_00570	COG2918	glutathione biosynthetic process
HFD83_00580	COG3501	Rhs element vgr protein
HFD83_00585	COG1388	LysM domain
HFD83_00585	COG0791	NLP P60 protein
HFD83_00600	COG3150	esterase
HFD83_00610	COG1028	Short-chain dehydrogenase reductase Sdr
HFD83_00615	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
HFD83_00625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HFD83_00635	COG2233	PERMEase
HFD83_00640	COG2351	hydroxyisourate hydrolase activity
HFD83_00675	COG3706	GGDEF domain
HFD83_00690	COG1393	Belongs to the ArsC family
HFD83_00695	COG0708	Exodeoxyribonuclease III
HFD83_00715	COG0189	ligase activity
HFD83_00735	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HFD83_00745	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HFD83_00760	COG4942	peptidase
HFD83_00770	COG0508	dehydrogenase complex catalyzes the overall conversion of
HFD83_00780	COG2119	membrane
HFD83_00790	COG2433	Pfam Transposase IS66
HFD83_00810	COG0426	domain, Protein
HFD83_00810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HFD83_00835	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HFD83_00855	COG1902	pentaerythritol trinitrate reductase activity
HFD83_00860	COG1519	Transferase
HFD83_00865	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HFD83_00870	COG0668	transmembrane transport
HFD83_00880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HFD83_00885	COG1335	isochorismatase
HFD83_00890	COG1522	sequence-specific DNA binding
HFD83_00895	COG3328	transposase activity
HFD83_00920	COG2205	protein histidine kinase activity
HFD83_00920	COG2198	Histidine kinase
HFD83_00920	COG0784	Response regulator, receiver
HFD83_00925	COG3162	membrane
HFD83_00930	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HFD83_00940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HFD83_00950	COG3706	GGDEF domain
HFD83_00960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HFD83_00965	COG1309	transcriptional regulator
HFD83_00985	COG0351	phosphomethylpyrimidine kinase
HFD83_00985	COG0352	thiamine-phosphate diphosphorylase activity
HFD83_00985	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HFD83_00995	COG2814	Major facilitator Superfamily
HFD83_01010	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HFD83_01020	COG1113	amino acid transport
HFD83_01030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HFD83_01035	COG1012	belongs to the aldehyde dehydrogenase family
HFD83_01045	COG1335	isochorismatase
HFD83_01060	COG1061	Type III restriction enzyme res subunit
HFD83_01070	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HFD83_01075	COG1192	Involved in chromosome partitioning
HFD83_01085	COG1061	Type III restriction enzyme res subunit
HFD83_01125	COG2814	Major facilitator Superfamily
HFD83_01130	COG0583	DNA-binding transcription factor activity
HFD83_01150	COG0667	Aldo Keto reductase
HFD83_01180	COG1733	regulation of RNA biosynthetic process
HFD83_01185	COG2249	NAD(P)H dehydrogenase (quinone) activity
HFD83_01250	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HFD83_01265	COG2329	Antibiotic biosynthesis monooxygenase
HFD83_01295	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HFD83_01325	COG0427	acetyl-CoA hydrolase
HFD83_01340	COG0745	RESPONSE REGULATOR receiver
HFD83_01350	COG0659	secondary active sulfate transmembrane transporter activity
HFD83_01355	COG4221	oxidoreductase activity
HFD83_01360	COG2873	o-acetylhomoserine
HFD83_01365	COG0488	(ABC) transporter
HFD83_01450	COG0833	amino acid
HFD83_01495	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HFD83_01500	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HFD83_01515	COG2226	methyltransferase
HFD83_01565	COG0067	glutamate synthase
HFD83_01565	COG0069	glutamate synthase activity
HFD83_01565	COG0070	glutamate synthase
HFD83_01570	COG0493	'glutamate synthase
HFD83_01580	COG1704	LemA family
HFD83_01585	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HFD83_01605	COG3307	-O-antigen
HFD83_01625	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HFD83_01640	COG0194	GDP metabolic process
HFD83_01690	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HFD83_01710	COG5380	lipid catabolic process
HFD83_01715	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HFD83_01740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HFD83_01745	COG0277	FAD linked oxidase domain protein
HFD83_01755	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HFD83_01760	COG2249	NAD(P)H dehydrogenase (quinone) activity
HFD83_01775	COG1289	transmembrane transporter activity
HFD83_01785	COG0628	permease
HFD83_01790	COG1192	Involved in chromosome partitioning
HFD83_01820	COG0833	amino acid
HFD83_01825	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HFD83_01830	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HFD83_01840	COG1012	belongs to the aldehyde dehydrogenase family
HFD83_01880	COG0583	DNA-binding transcription factor activity
HFD83_01925	COG0517	IMP dehydrogenase activity
HFD83_01930	COG1983	PspC domain protein
HFD83_01940	COG1960	acyl-CoA dehydrogenase activity
HFD83_01955	COG0408	coproporphyrinogen oxidase activity
HFD83_01975	COG0513	Belongs to the DEAD box helicase family
HFD83_01985	COG1127	ABC transporter
HFD83_01990	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HFD83_02000	COG2854	intermembrane phospholipid transfer
HFD83_02010	COG0598	Magnesium transport protein CorA
HFD83_02020	COG0494	nUDIX hydrolase
HFD83_02025	COG1040	competence protein
HFD83_02030	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HFD83_02050	COG1946	Acyl-CoA thioesterase
HFD83_02055	COG1301	dicarboxylic acid transport
HFD83_02070	COG1959	2 iron, 2 sulfur cluster binding
HFD83_02075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HFD83_02075	COG1017	nitric oxide dioxygenase activity
HFD83_02080	COG0433	COG0433 Predicted ATPase
HFD83_02085	COG0626	cystathionine gamma-synthase activity
HFD83_02240	COG1960	acyl-CoA dehydrogenase activity
HFD83_02245	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HFD83_02275	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HFD83_02280	COG0339	signal peptide processing
HFD83_02285	COG0557	exoribonuclease II activity
HFD83_02330	COG0179	Fumarylacetoacetate (FAA) hydrolase
HFD83_02335	COG2169	Transcriptional regulator
HFD83_02340	COG0697	spore germination
HFD83_02345	COG1295	ribonuclease BN
HFD83_02380	COG1702	phosphate starvation-inducible protein PhoH
HFD83_02390	COG0741	lytic transglycosylase activity
HFD83_02390	COG1196	nuclear chromosome segregation
HFD83_02390	COG0739	heme binding
HFD83_02420	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HFD83_02425	COG1183	phosphatidylcholine synthase activity
HFD83_02470	COG1960	acyl-CoA dehydrogenase activity
HFD83_02475	COG1309	transcriptional regulator
HFD83_02490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HFD83_02495	COG1960	acyl-CoA dehydrogenase activity
HFD83_02515	COG2969	positive regulation of protein catabolic process
HFD83_02525	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HFD83_02540	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HFD83_02545	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HFD83_02565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HFD83_02575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFD83_02580	COG1408	metallophosphoesterase
HFD83_02590	COG2199	diguanylate cyclase activity
HFD83_02650	COG1607	acyl-coa hydrolase
HFD83_02680	COG2350	Protein conserved in bacteria
HFD83_02690	COG0613	PHP domain protein
HFD83_02695	COG3781	membrane
HFD83_02705	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HFD83_02710	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HFD83_02720	COG1862	Preprotein translocase
HFD83_02765	COG2205	protein histidine kinase activity
HFD83_02770	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HFD83_02790	COG0726	polysaccharide deacetylase
HFD83_02795	COG0463	Glycosyl transferase, family 2
HFD83_02800	COG0438	transferase activity, transferring glycosyl groups
HFD83_02865	COG0625	glutathione transferase activity
HFD83_02870	COG0583	DNA-binding transcription factor activity
HFD83_02875	COG1960	acyl-CoA dehydrogenase activity
HFD83_02880	COG1960	acyl-CoA dehydrogenase activity
HFD83_02890	COG2205	protein histidine kinase activity
HFD83_02895	COG0745	RESPONSE REGULATOR receiver
HFD83_02900	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HFD83_02920	COG2096	Adenosyltransferase
HFD83_02970	COG0285	dihydrofolate synthase activity
HFD83_02990	COG0450	alkyl hydroperoxide reductase
HFD83_03005	COG0477	Major facilitator Superfamily
HFD83_03010	COG1272	protein, Hemolysin III
HFD83_03045	COG0183	Belongs to the thiolase family
HFD83_03050	COG2207	Transcriptional regulator
HFD83_03070	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HFD83_03090	COG0183	Belongs to the thiolase family
HFD83_03100	COG2885	chlorophyll binding
HFD83_03100	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HFD83_03110	COG1690	Belongs to the RtcB family
HFD83_03115	COG0833	amino acid
HFD83_03125	COG2233	PERMEase
HFD83_03155	COG2094	Belongs to the DNA glycosylase MPG family
HFD83_03160	COG4772	TonB-dependent receptor
HFD83_03175	COG1902	pentaerythritol trinitrate reductase activity
HFD83_03190	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HFD83_03195	COG0354	folic acid binding
HFD83_03205	COG3189	MarR family transcriptional regulator
HFD83_03210	COG2824	Alkylphosphonate utilization operon protein PhnA
HFD83_03215	COG3422	double-strand break repair
HFD83_03255	COG0840	transmembrane signaling receptor activity
HFD83_03275	COG5510	response to toxic substance
HFD83_03285	COG2832	Protein of unknown function (DUF454)
HFD83_03290	COG1376	ErfK ybiS ycfS ynhG family protein
HFD83_03330	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HFD83_03340	COG1289	transmembrane transporter activity
HFD83_03345	COG2814	Major facilitator Superfamily
HFD83_03365	COG1115	amino acid carrier protein
HFD83_03370	COG1752	Esterase of the alpha-beta hydrolase superfamily
HFD83_03375	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HFD83_03380	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HFD83_03410	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFD83_03420	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFD83_03425	COG1077	Cell shape determining protein MreB Mrl
HFD83_03430	COG1792	Involved in formation and maintenance of cell shape
HFD83_03435	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HFD83_03440	COG0424	maF-like protein
HFD83_03445	COG1530	ribonuclease E activity
HFD83_03455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HFD83_03465	COG0560	Phosphoserine phosphatase
HFD83_03475	COG2249	NAD(P)H dehydrogenase (quinone) activity
HFD83_03500	COG2207	Transcriptional regulator
HFD83_03520	COG1113	amino acid transport
HFD83_03525	COG2828	Protein conserved in bacteria
HFD83_03530	COG0142	geranyltranstransferase activity
HFD83_03535	COG2315	Protein conserved in bacteria
HFD83_03550	COG1752	Esterase of the alpha-beta hydrolase superfamily
HFD83_03570	COG2194	sulfuric ester hydrolase activity
HFD83_03575	COG0745	RESPONSE REGULATOR receiver
HFD83_03580	COG0642	Histidine kinase
HFD83_03590	COG0004	ammonium transporteR
HFD83_03595	COG0583	DNA-binding transcription factor activity
HFD83_03615	COG0525	valine-tRNA ligase activity
HFD83_03625	COG1028	Short-chain dehydrogenase reductase Sdr
HFD83_03635	COG0393	Putative heavy-metal-binding
HFD83_03640	COG0393	Putative heavy-metal-binding
HFD83_03645	COG1538	Outer membrane efflux protein
HFD83_03655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HFD83_03660	COG0671	phosphoesterase, PA-phosphatase related
HFD83_03690	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HFD83_03705	COG1648	precorrin-2 dehydrogenase activity
HFD83_03705	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HFD83_03710	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HFD83_03715	COG1733	regulation of RNA biosynthetic process
HFD83_03725	COG0531	amino acid
HFD83_03740	COG0321	lipoyl(octanoyl) transferase activity
HFD83_03745	COG2921	Belongs to the UPF0250 family
HFD83_03785	COG2009	succinate dehydrogenase
HFD83_03790	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HFD83_03795	COG1053	succinate dehydrogenase
HFD83_03800	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HFD83_03825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HFD83_03845	COG2354	Protein conserved in bacteria
HFD83_03850	COG2321	neutral zinc metallopeptidase
HFD83_03890	COG2843	Capsule synthesis protein
HFD83_03905	COG0589	response to stress
HFD83_03925	COG0505	Belongs to the CarA family
HFD83_03950	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HFD83_03955	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HFD83_04005	COG0477	Major facilitator Superfamily
HFD83_04010	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HFD83_04025	COG1597	lipid kinase activity
HFD83_04030	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HFD83_04055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HFD83_04060	COG0584	glycerophosphoryl diester phosphodiesterase
HFD83_04080	COG0741	lytic transglycosylase activity
HFD83_04100	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HFD83_04115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HFD83_04140	COG0778	Nitroreductase
HFD83_04155	COG1929	Belongs to the glycerate kinase type-1 family
HFD83_04160	COG0243	molybdopterin cofactor binding
HFD83_04165	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HFD83_04170	COG3339	Conserved Protein
HFD83_04180	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
HFD83_04195	COG1113	amino acid transport
HFD83_04205	COG0019	diaminopimelate decarboxylase activity
HFD83_04215	COG1280	lysine exporter protein (LysE YggA)
HFD83_04220	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HFD83_04250	COG0463	Glycosyl transferase, family 2
HFD83_04270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HFD83_04305	COG4591	ABC-type transport system involved in lipoprotein release permease component
HFD83_04310	COG1136	(ABC) transporter
HFD83_04315	COG0658	competence protein
HFD83_04315	COG2333	competence protein COMEC
HFD83_04325	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HFD83_04325	COG0616	signal peptide processing
HFD83_04330	COG0596	Alpha beta hydrolase
HFD83_04335	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HFD83_04345	COG0628	permease
HFD83_04380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFD83_04400	COG0823	Involved in the tonB-independent uptake of proteins
HFD83_04420	COG0824	Thioesterase
HFD83_04425	COG1473	amidohydrolase
HFD83_04445	COG0047	phosphoribosylformylglycinamidine synthase activity
HFD83_04445	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFD83_04450	COG2814	Major facilitator Superfamily
HFD83_04460	COG1024	Enoyl-CoA hydratase
HFD83_04465	COG1056	cytidyltransferase-related domain
HFD83_04465	COG1051	belongs to the nudix hydrolase family
HFD83_04475	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HFD83_04490	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HFD83_04505	COG4625	pathogenesis
HFD83_04510	COG0583	DNA-binding transcription factor activity
HFD83_04515	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HFD83_04520	COG4208	sulfate ABC transporter
HFD83_04525	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HFD83_04535	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HFD83_04540	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HFD83_04545	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HFD83_04565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HFD83_04580	COG0681	Belongs to the peptidase S26 family
HFD83_04595	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HFD83_04605	COG1381	Involved in DNA repair and RecF pathway recombination
HFD83_04610	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HFD83_04620	COG4221	oxidoreductase activity
HFD83_04650	COG0436	Aminotransferase
HFD83_04670	COG0556	nucleotide-excision repair
HFD83_04725	COG2070	2-Nitropropane dioxygenase
HFD83_04755	COG1215	transferase activity, transferring glycosyl groups
HFD83_04770	COG0415	Belongs to the DNA photolyase family
HFD83_04780	COG1252	NADH dehydrogenase
HFD83_04785	COG1686	Belongs to the peptidase S11 family
HFD83_04800	COG1187	pseudouridine synthase activity
HFD83_04825	COG0477	Major facilitator Superfamily
HFD83_04830	COG0583	DNA-binding transcription factor activity
HFD83_04845	COG0612	Peptidase, M16
HFD83_04880	COG0352	thiamine-phosphate diphosphorylase activity
HFD83_04915	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HFD83_04930	COG1309	transcriptional regulator
HFD83_04940	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HFD83_04945	COG0076	glutamate decarboxylase activity
HFD83_04955	COG1522	sequence-specific DNA binding
HFD83_04960	COG3961	Belongs to the TPP enzyme family
HFD83_04965	COG1113	amino acid transport
HFD83_04970	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HFD83_04975	COG0573	inorganic phosphate transmembrane transporter activity
HFD83_04985	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HFD83_04990	COG0616	signal peptide processing
HFD83_05025	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HFD83_05030	COG1686	Belongs to the peptidase S11 family
HFD83_05055	COG0583	DNA-binding transcription factor activity
HFD83_05060	COG1067	ATP-dependent peptidase activity
HFD83_05105	COG1966	Carbon starvation protein
HFD83_05110	COG2879	small protein
HFD83_05145	COG2508	Transcriptional regulator
HFD83_05145	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HFD83_05165	COG1113	amino acid transport
HFD83_05170	COG0583	DNA-binding transcription factor activity
HFD83_05175	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HFD83_05180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HFD83_05190	COG1012	belongs to the aldehyde dehydrogenase family
HFD83_05195	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HFD83_05200	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HFD83_05200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HFD83_05235	COG2814	Major facilitator Superfamily
HFD83_05240	COG4948	Mandelate Racemase Muconate Lactonizing
HFD83_05250	COG1309	transcriptional regulator
HFD83_05275	COG1741	Belongs to the pirin family
HFD83_05285	COG2964	Protein conserved in bacteria
HFD83_05300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HFD83_05305	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFD83_05310	COG4605	iron ion homeostasis
HFD83_05315	COG4604	ABC transporter, ATP-binding protein
HFD83_05320	COG4607	ABC-type enterochelin transport system periplasmic component
HFD83_05325	COG4774	siderophore transport
HFD83_05335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HFD83_05340	COG1021	2,3-dihydroxybenzoate-AMP ligase
HFD83_05345	COG1535	isochorismatase
HFD83_05345	COG3433	isochorismatase activity
HFD83_05360	COG1132	(ABC) transporter
HFD83_05370	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HFD83_05380	COG1169	isochorismate synthase
HFD83_05395	COG3739	integral membrane protein
HFD83_05430	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HFD83_05460	COG0308	aminopeptidase N
HFD83_05465	COG0512	Glutamine amidotransferase of anthranilate synthase
HFD83_05475	COG3104	oligopeptide transport
HFD83_05480	COG0174	glutamine synthetase
HFD83_05490	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HFD83_05525	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HFD83_05530	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HFD83_05535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HFD83_05555	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HFD83_05560	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HFD83_05565	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HFD83_05580	COG1960	acyl-CoA dehydrogenase activity
HFD83_05585	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HFD83_05590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HFD83_05600	COG2223	nitrite transmembrane transporter activity
HFD83_05610	COG0024	Methionine aminopeptidase
HFD83_05615	COG0052	Belongs to the universal ribosomal protein uS2 family
HFD83_05630	COG2207	Transcriptional regulator
HFD83_05655	COG2951	lytic endotransglycosylase activity
HFD83_05660	COG0772	Belongs to the SEDS family
HFD83_05675	COG0842	Transport permease protein
HFD83_05680	COG1131	(ABC) transporter
HFD83_05725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HFD83_05740	COG4215	(ABC) transporter
HFD83_05745	COG4160	amino acid transport
HFD83_05750	COG4598	ABC transporter
HFD83_05760	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HFD83_05770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HFD83_05785	COG1720	tRNA m6t6A37 methyltransferase activity
HFD83_05805	COG0745	RESPONSE REGULATOR receiver
HFD83_05810	COG0642	Histidine kinase
HFD83_05820	COG0494	nUDIX hydrolase
HFD83_05830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HFD83_05835	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HFD83_05840	COG3139	Protein of unknown function (DUF1315)
HFD83_05845	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HFD83_05850	COG1301	dicarboxylic acid transport
HFD83_05855	COG1960	acyl-CoA dehydrogenase activity
HFD83_05860	COG2819	hydrolase of the alpha beta superfamily
HFD83_05870	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HFD83_05880	COG2195	Cleaves the N-terminal amino acid of tripeptides
HFD83_05885	COG1234	tRNA 3'-trailer cleavage
HFD83_05915	COG2363	Small membrane protein
HFD83_05935	COG0513	Belongs to the DEAD box helicase family
HFD83_05945	COG0778	Nitroreductase
HFD83_06285	COG1286	toxin biosynthetic process
HFD83_06310	COG4783	chaperone-mediated protein folding
HFD83_06315	COG1610	YqeY-like protein
HFD83_06415	COG3111	PFAM Bacterial OB fold (BOF) protein
HFD83_06440	COG3243	poly(R)-hydroxyalkanoic acid synthase
HFD83_06445	COG0786	glutamate:sodium symporter activity
HFD83_06455	COG2186	Transcriptional regulator
HFD83_06505	COG0477	Major facilitator Superfamily
HFD83_06530	COG2985	domain, Protein
HFD83_06540	COG2995	paraquat-inducible protein a
HFD83_06545	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HFD83_06545	COG3008	intermembrane lipid transfer
HFD83_06555	COG1794	racemase activity, acting on amino acids and derivatives
HFD83_06640	COG0482	sulfurtransferase activity
HFD83_06660	COG3173	Aminoglycoside phosphotransferase
HFD83_06670	COG2433	Pfam Transposase IS66
HFD83_06710	COG1301	dicarboxylic acid transport
HFD83_06720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HFD83_06725	COG2011	ABC-type metal ion transport system permease component
HFD83_06730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HFD83_06735	COG1464	Belongs to the NlpA lipoprotein family
HFD83_06740	COG0151	Belongs to the GarS family
HFD83_06745	COG0138	bifunctional purine biosynthesis protein purh
HFD83_06750	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HFD83_06780	COG2308	Evidence 4 Homologs of previously reported genes of
HFD83_06790	COG1305	Transglutaminase-like
HFD83_06800	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HFD83_06805	COG0305	Participates in initiation and elongation during chromosome replication
HFD83_06830	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HFD83_06840	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HFD83_06845	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HFD83_06870	COG0726	polysaccharide deacetylase
HFD83_06870	COG1649	PFAM Uncharacterised BCR, COG1649
HFD83_06875	COG1215	transferase activity, transferring glycosyl groups
HFD83_06880	COG3658	cytochrome
HFD83_06890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HFD83_06905	COG0583	DNA-binding transcription factor activity
HFD83_06925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HFD83_06930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HFD83_06945	COG1960	acyl-CoA dehydrogenase activity
HFD83_06950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HFD83_06955	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HFD83_06980	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HFD83_06985	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HFD83_06995	COG2205	protein histidine kinase activity
HFD83_07000	COG0745	RESPONSE REGULATOR receiver
HFD83_07005	COG0174	glutamine synthetase
HFD83_07025	COG0729	surface antigen
HFD83_07050	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HFD83_07055	COG2814	Major facilitator Superfamily
HFD83_07070	COG0583	DNA-binding transcription factor activity
HFD83_07085	COG1187	pseudouridine synthase activity
HFD83_07105	COG0802	atpase or kinase
HFD83_07110	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HFD83_07120	COG1923	regulation of RNA biosynthetic process
HFD83_07125	COG0697	spore germination
HFD83_07140	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HFD83_07150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HFD83_07155	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HFD83_07155	COG0519	Catalyzes the synthesis of GMP from XMP
HFD83_07160	COG4302	ethanolamine ammonia-lyase activity
HFD83_07165	COG4303	Ethanolamine ammonia lyase large subunit
HFD83_07170	COG0531	amino acid
HFD83_07190	COG1454	alcohol dehydrogenase
HFD83_07195	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HFD83_07205	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HFD83_07225	COG0308	aminopeptidase N
HFD83_07235	COG4221	oxidoreductase activity
HFD83_07245	COG1605	Chorismate mutase
HFD83_07260	COG1309	transcriptional regulator
HFD83_07270	COG0668	transmembrane transport
HFD83_07305	COG4773	Receptor
HFD83_07325	COG0488	(ABC) transporter
HFD83_07330	COG0589	response to stress
HFD83_07355	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HFD83_07365	COG3135	benzoate transporter
HFD83_07370	COG1522	sequence-specific DNA binding
HFD83_07380	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HFD83_07385	COG0583	DNA-binding transcription factor activity
HFD83_07395	COG0183	Belongs to the thiolase family
HFD83_07405	COG2030	dehydratase
HFD83_07425	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFD83_07435	COG0824	Thioesterase
HFD83_07440	COG1454	alcohol dehydrogenase
HFD83_07450	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HFD83_07470	COG0069	glutamate synthase activity
HFD83_07490	COG2814	Major facilitator Superfamily
HFD83_07505	COG0511	ligase activity, forming carbon-carbon bonds
HFD83_07525	COG1116	anion transmembrane transporter activity
HFD83_07525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HFD83_07530	COG0745	RESPONSE REGULATOR receiver
HFD83_07540	COG2146	nitrite reductase [NAD(P)H] activity
HFD83_07540	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HFD83_07545	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HFD83_07550	COG0243	molybdopterin cofactor binding
HFD83_07560	COG0243	molybdopterin cofactor binding
HFD83_07565	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HFD83_07580	COG0315	cyclic pyranopterin monophosphate synthase activity
HFD83_07580	COG0521	Mo-molybdopterin cofactor biosynthetic process
HFD83_07585	COG0303	'Molybdopterin
HFD83_07595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HFD83_07600	COG0697	spore germination
HFD83_07620	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HFD83_07625	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HFD83_07680	COG2204	response regulator
HFD83_07685	COG3852	Histidine kinase
HFD83_07705	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HFD83_07710	COG0575	Belongs to the CDS family
HFD83_07745	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HFD83_07760	COG2137	regulation of response to DNA damage stimulus
HFD83_07770	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HFD83_07775	COG1011	Hydrolase
HFD83_07800	COG1522	sequence-specific DNA binding
HFD83_07810	COG1113	amino acid transport
HFD83_07825	COG0659	secondary active sulfate transmembrane transporter activity
HFD83_07830	COG2135	peptidase activity
HFD83_07845	COG5001	Diguanylate cyclase
HFD83_07845	COG3300	MHYT domain
HFD83_07865	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HFD83_07865	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HFD83_07865	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HFD83_07870	COG1105	Belongs to the carbohydrate kinase PfkB family
HFD83_07875	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HFD83_07875	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HFD83_07905	COG0024	Methionine aminopeptidase
HFD83_07910	COG0583	DNA-binding transcription factor activity
HFD83_07920	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HFD83_07925	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HFD83_07930	COG0516	GMP reductase activity
HFD83_07930	COG0517	IMP dehydrogenase activity
HFD83_07955	COG0552	protein localization to endoplasmic reticulum
HFD83_07965	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HFD83_07980	COG4890	Cyd operon protein YbgT
HFD83_07985	COG1294	oxidase, subunit
HFD83_08000	COG1585	Membrane protein implicated in regulation of membrane protease activity
HFD83_08010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HFD83_08015	COG4774	siderophore transport
HFD83_08030	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HFD83_08035	COG0569	domain protein
HFD83_08040	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HFD83_08070	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HFD83_08075	COG0542	response to heat
HFD83_08100	COG1902	pentaerythritol trinitrate reductase activity
HFD83_08100	COG0446	pyridine nucleotide-disulphide oxidoreductase
HFD83_08145	COG2323	membrane
HFD83_08150	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HFD83_08160	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HFD83_08165	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HFD83_08170	COG0183	Belongs to the thiolase family
HFD83_08175	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HFD83_08180	COG0596	Alpha beta hydrolase
HFD83_08185	COG2271	Major facilitator Superfamily
HFD83_08190	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HFD83_08195	COG3485	protocatechuate 3,4-dioxygenase
HFD83_08200	COG3485	protocatechuate 3,4-dioxygenase
HFD83_08205	COG0710	3-dehydroquinate dehydratase activity
HFD83_08210	COG3420	alginic acid biosynthetic process
HFD83_08215	COG3659	wide pore channel activity
HFD83_08220	COG4993	Dehydrogenase
HFD83_08230	COG2391	methyltransferase activity
HFD83_08245	COG1414	Transcriptional regulator
HFD83_08250	COG0583	DNA-binding transcription factor activity
HFD83_08255	COG1960	acyl-CoA dehydrogenase activity
HFD83_08280	COG2814	Major facilitator Superfamily
HFD83_08290	COG0154	amidase activity
HFD83_08310	COG4638	Rieske (2fe-2S)
HFD83_08320	COG1028	Short-chain dehydrogenase reductase Sdr
HFD83_08330	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HFD83_08340	COG3733	amine oxidase
HFD83_08350	COG1012	belongs to the aldehyde dehydrogenase family
HFD83_08360	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HFD83_08365	COG0183	Belongs to the thiolase family
HFD83_08370	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HFD83_08375	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HFD83_08385	COG4829	muconolactone delta-isomerase
HFD83_08390	COG4948	Mandelate Racemase Muconate Lactonizing
HFD83_08395	COG0583	DNA-binding transcription factor activity
HFD83_08405	COG2186	Transcriptional regulator
HFD83_08425	COG1012	belongs to the aldehyde dehydrogenase family
HFD83_08445	COG1960	acyl-CoA dehydrogenase activity
HFD83_08450	COG1028	Short-chain dehydrogenase reductase Sdr
HFD83_08455	COG3829	transcription factor binding
HFD83_08465	COG3162	membrane
HFD83_08480	COG1012	belongs to the aldehyde dehydrogenase family
HFD83_08495	COG0753	catalase activity
HFD83_08515	COG1846	Transcriptional regulator
HFD83_08520	COG1902	pentaerythritol trinitrate reductase activity
HFD83_08520	COG0446	pyridine nucleotide-disulphide oxidoreductase
HFD83_08530	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HFD83_08560	COG1309	transcriptional regulator
HFD83_08570	COG1335	isochorismatase
HFD83_08575	COG0583	DNA-binding transcription factor activity
HFD83_08585	COG0475	glutathione-regulated potassium exporter activity
HFD83_08585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HFD83_08595	COG1473	amidohydrolase
HFD83_08605	COG2831	hemolysin activation secretion protein
HFD83_08610	COG3210	domain, Protein
HFD83_08640	COG2188	Transcriptional regulator
HFD83_08655	COG0583	DNA-binding transcription factor activity
HFD83_08685	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HFD83_08705	COG1566	PFAM secretion protein HlyD family protein
HFD83_08720	COG1012	belongs to the aldehyde dehydrogenase family
HFD83_08725	COG0129	dihydroxy-acid dehydratase activity
HFD83_08735	COG0583	DNA-binding transcription factor activity
HFD83_08740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HFD83_08750	COG2084	Dehydrogenase
HFD83_08755	COG2207	Transcriptional regulator
HFD83_08770	COG1064	alcohol dehydrogenase
HFD83_08785	COG1120	ATPase activity
HFD83_08805	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFD83_08920	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HFD83_08970	COG1028	Short-chain dehydrogenase reductase Sdr
HFD83_08985	COG2207	Transcriptional regulator
HFD83_08995	COG2205	protein histidine kinase activity
HFD83_09000	COG0745	RESPONSE REGULATOR receiver
HFD83_09005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HFD83_09010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HFD83_09015	COG1538	Outer membrane efflux protein
HFD83_09025	COG2072	flavoprotein involved in K transport
HFD83_09045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HFD83_09065	COG3539	Fimbrial protein
HFD83_09095	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HFD83_09105	COG0753	catalase activity
HFD83_09120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFD83_09185	COG1535	isochorismatase
HFD83_09185	COG3433	isochorismatase activity
HFD83_09190	COG1028	Short-chain dehydrogenase reductase Sdr
HFD83_09195	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HFD83_09200	COG4149	molybdate abc transporter
HFD83_09205	COG0725	ABC transporter, periplasmic molybdate-binding protein
HFD83_09215	COG4638	Rieske (2fe-2S)
HFD83_09220	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HFD83_09225	COG0543	2 iron, 2 sulfur cluster binding
HFD83_09225	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HFD83_09250	COG1028	Short-chain dehydrogenase reductase Sdr
HFD83_09265	COG2207	Transcriptional regulator
HFD83_09275	COG1028	Short-chain dehydrogenase reductase Sdr
HFD83_09280	COG2610	gluconate transmembrane transporter activity
HFD83_09290	COG0583	DNA-binding transcription factor activity
HFD83_09300	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HFD83_09305	COG2031	fatty acid transporter
HFD83_09310	COG0183	Belongs to the thiolase family
HFD83_09315	COG0583	DNA-binding transcription factor activity
HFD83_09320	COG0583	DNA-binding transcription factor activity
HFD83_09335	COG1027	Aspartate ammonia-lyase
HFD83_09345	COG0477	Major facilitator Superfamily
HFD83_09365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HFD83_09370	COG4521	taurine ABC transporter
HFD83_09385	COG2188	Transcriptional regulator
HFD83_09395	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HFD83_09400	COG1733	regulation of RNA biosynthetic process
HFD83_09405	COG3708	Transcriptional regulator
HFD83_09405	COG2207	Transcriptional regulator
HFD83_09420	COG0730	response to heat
HFD83_09430	COG3453	Protein conserved in bacteria
HFD83_09430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HFD83_09440	COG3781	membrane
HFD83_09445	COG1063	alcohol dehydrogenase
HFD83_09455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HFD83_09460	COG0508	dehydrogenase complex catalyzes the overall conversion of
HFD83_09465	COG0022	dehydrogenase e1 component
HFD83_09470	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HFD83_09475	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HFD83_09490	COG3706	GGDEF domain
HFD83_09505	COG0133	tryptophan synthase activity
HFD83_09515	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HFD83_09550	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HFD83_09635	COG0842	Transport permease protein
HFD83_09640	COG0842	Transport permease protein
HFD83_09645	COG1131	(ABC) transporter
HFD83_09660	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HFD83_09665	COG4773	Receptor
HFD83_09685	COG0730	response to heat
HFD83_09690	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HFD83_09710	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HFD83_09765	COG4264	IucA IucC family
HFD83_09770	COG4264	IucA IucC family
HFD83_09790	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HFD83_09805	COG1960	acyl-CoA dehydrogenase activity
HFD83_09810	COG1960	acyl-CoA dehydrogenase activity
HFD83_09815	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HFD83_09820	COG2207	Transcriptional regulator
HFD83_09825	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HFD83_09830	COG0776	regulation of translation
HFD83_09855	COG0822	iron-sulfur transferase activity
HFD83_09860	COG0316	Belongs to the HesB IscA family
HFD83_09890	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HFD83_09910	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HFD83_09915	COG0702	epimerase
HFD83_09950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFD83_09960	COG0339	signal peptide processing
HFD83_10010	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HFD83_10015	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HFD83_10045	COG0776	regulation of translation
HFD83_10110	COG0084	hydrolase, TatD family'
HFD83_10130	COG1663	tetraacyldisaccharide 4'-kinase activity
HFD83_10135	COG1132	(ABC) transporter
HFD83_10145	COG0811	peptide transport
HFD83_10150	COG1475	DNA binding
HFD83_10155	COG1192	Involved in chromosome partitioning
HFD83_10165	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HFD83_10180	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HFD83_10185	COG0191	fructose-bisphosphate aldolase activity
HFD83_10205	COG0424	maF-like protein
HFD83_10210	COG2850	peptidyl-arginine hydroxylation
HFD83_10220	COG0640	Transcriptional regulator
HFD83_10230	COG3619	membrane
HFD83_10235	COG3122	Protein conserved in bacteria
HFD83_10240	COG1132	(ABC) transporter
HFD83_10260	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HFD83_10265	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HFD83_10275	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HFD83_10275	COG0506	proline dehydrogenase activity
HFD83_10275	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HFD83_10280	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HFD83_10295	COG3698	Phosphodiester glycosidase
HFD83_10305	COG2353	YceI-like domain
HFD83_10315	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HFD83_10360	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HFD83_10360	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HFD83_10385	COG3539	Fimbrial protein
HFD83_10390	COG3121	Chaperone
HFD83_10415	COG0697	spore germination
HFD83_10425	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HFD83_10435	COG0583	DNA-binding transcription factor activity
HFD83_10455	COG1309	transcriptional regulator
HFD83_10470	COG1522	sequence-specific DNA binding
HFD83_10480	COG1126	abc transporter atp-binding protein
HFD83_10485	COG0765	amino acid transport
HFD83_10490	COG0765	amino acid transport
HFD83_10520	COG1464	Belongs to the NlpA lipoprotein family
HFD83_10530	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HFD83_10535	COG2011	ABC-type metal ion transport system permease component
HFD83_10540	COG0012	GTP binding
HFD83_10565	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HFD83_10605	COG0386	Belongs to the glutathione peroxidase family
HFD83_10615	COG0436	Aminotransferase
HFD83_10655	COG3634	alkyl hydroperoxide reductase activity
HFD83_10670	COG0583	DNA-binding transcription factor activity
HFD83_10675	COG0798	PFAM Bile acid sodium symporter
HFD83_10680	COG0640	Transcriptional regulator
HFD83_10695	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HFD83_10705	COG0583	DNA-binding transcription factor activity
HFD83_10715	COG1953	Uracil, thiamine, allantoin
HFD83_10725	COG2175	clavaminate synthase activity
HFD83_10730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HFD83_10735	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HFD83_10740	COG4521	taurine ABC transporter
HFD83_10750	COG0477	Major facilitator Superfamily
HFD83_10775	COG1271	oxidase subunit
HFD83_10780	COG1294	oxidase, subunit
HFD83_10790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HFD83_10810	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HFD83_10830	COG3052	prosthetic group binding
HFD83_10835	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
HFD83_10845	COG2814	Major facilitator Superfamily
HFD83_10865	COG1346	cytolysis
HFD83_10875	COG0583	DNA-binding transcription factor activity
HFD83_10880	COG0625	glutathione transferase activity
HFD83_10885	COG0625	glutathione transferase activity
HFD83_10890	COG0583	DNA-binding transcription factor activity
HFD83_10905	COG1045	serine acetyltransferase
HFD83_10910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HFD83_10915	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HFD83_10925	COG1280	lysine exporter protein (LysE YggA)
HFD83_10940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HFD83_10945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HFD83_10950	COG1126	abc transporter atp-binding protein
HFD83_10955	COG0765	amino acid transport
HFD83_10960	COG0765	amino acid transport
HFD83_10980	COG0784	Response regulator, receiver
HFD83_10980	COG2205	protein histidine kinase activity
HFD83_11000	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HFD83_11020	COG1028	Short-chain dehydrogenase reductase Sdr
HFD83_11070	COG0583	DNA-binding transcription factor activity
HFD83_11090	COG0318	PFAM AMP-dependent synthetase and ligase
HFD83_11095	COG1309	transcriptional regulator
HFD83_11100	COG1960	acyl-CoA dehydrogenase activity
HFD83_11105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HFD83_11110	COG1024	Enoyl-CoA hydratase
HFD83_11115	COG4770	biotin carboxylase activity
HFD83_11125	COG0583	DNA-binding transcription factor activity
HFD83_11140	COG1960	acyl-CoA dehydrogenase activity
HFD83_11150	COG2814	Major facilitator Superfamily
HFD83_11160	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HFD83_11165	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HFD83_11170	COG2814	Major facilitator Superfamily
HFD83_11175	COG1960	acyl-CoA dehydrogenase activity
HFD83_11180	COG1024	Enoyl-CoA hydratase
HFD83_11185	COG1028	Short-chain dehydrogenase reductase Sdr
HFD83_11190	COG1250	3-hydroxyacyl-CoA dehydrogenase
HFD83_11195	COG0183	Belongs to the thiolase family
HFD83_11205	COG2814	Major facilitator Superfamily
HFD83_11215	COG1024	Enoyl-CoA hydratase
HFD83_11230	COG1960	acyl-CoA dehydrogenase activity
HFD83_11235	COG2814	Major facilitator Superfamily
HFD83_11240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HFD83_11245	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HFD83_11260	COG3842	ATPase activity
HFD83_11265	COG1840	ABC-type Fe3 transport system, periplasmic component
HFD83_11275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HFD83_11280	COG1414	Transcriptional regulator
HFD83_11290	COG0583	DNA-binding transcription factor activity
HFD83_11295	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HFD83_11300	COG1012	belongs to the aldehyde dehydrogenase family
HFD83_11310	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HFD83_11320	COG1012	belongs to the aldehyde dehydrogenase family
HFD83_11325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HFD83_11330	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HFD83_11335	COG2267	carboxylic ester hydrolase activity
HFD83_11355	COG3038	cytochrome b561
HFD83_11360	COG0753	catalase activity
HFD83_11395	COG2050	protein possibly involved in aromatic compounds catabolism
HFD83_11405	COG3327	negative regulation of DNA-templated transcription, initiation
HFD83_11410	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HFD83_11415	COG0183	Belongs to the thiolase family
HFD83_11420	COG1250	3-hydroxyacyl-CoA dehydrogenase
HFD83_11425	COG1024	Enoyl-CoA hydratase
HFD83_11430	COG1024	Enoyl-CoA hydratase
HFD83_11435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HFD83_11440	COG2151	metal-sulfur cluster biosynthetic enzyme
HFD83_11445	COG3396	Phenylacetate-CoA oxygenase
HFD83_11450	COG3460	Phenylacetate-CoA oxygenase
HFD83_11455	COG3396	Phenylacetate-CoA oxygenase
HFD83_11460	COG1012	belongs to the aldehyde dehydrogenase family
HFD83_11460	COG2030	dehydratase
HFD83_11465	COG1760	l-serine dehydratase
HFD83_11470	COG0531	amino acid
HFD83_11475	COG1012	belongs to the aldehyde dehydrogenase family
HFD83_11490	COG0446	pyridine nucleotide-disulphide oxidoreductase
HFD83_11500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HFD83_11520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HFD83_11530	COG0789	Transcriptional regulator
HFD83_11545	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HFD83_11560	COG2807	transmembrane transport
HFD83_11565	COG0590	tRNA wobble adenosine to inosine editing
HFD83_11680	COG1116	anion transmembrane transporter activity
HFD83_11685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HFD83_11695	COG0864	Transcriptional regulator
HFD83_11715	COG2249	NAD(P)H dehydrogenase (quinone) activity
HFD83_11720	COG0439	Biotin carboxylase
HFD83_11735	COG1063	alcohol dehydrogenase
HFD83_11745	COG1309	transcriptional regulator
HFD83_11765	COG0038	chloride channel
HFD83_11770	COG4770	biotin carboxylase activity
HFD83_11790	COG1914	H( )-stimulated, divalent metal cation uptake system
HFD83_11795	COG0583	DNA-binding transcription factor activity
HFD83_11810	COG3209	COG3209 Rhs family protein
HFD83_11815	COG3501	Rhs element vgr protein
HFD83_11850	COG1250	3-hydroxyacyl-CoA dehydrogenase
HFD83_11870	COG2814	Major facilitator Superfamily
HFD83_11880	COG1560	Kdo2-lipid A biosynthetic process
HFD83_11890	COG5006	permease, DMT superfamily
HFD83_11895	COG1522	sequence-specific DNA binding
HFD83_11910	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HFD83_11920	COG4122	O-methyltransferase activity
HFD83_11950	COG1538	Outer membrane efflux protein
HFD83_11960	COG1137	ATPase activity
HFD83_11965	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HFD83_11975	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HFD83_11980	COG0517	IMP dehydrogenase activity
HFD83_11980	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HFD83_12020	COG2814	Major facilitator Superfamily
HFD83_12055	COG1278	Cold shock
HFD83_12060	COG1280	lysine exporter protein (LysE YggA)
HFD83_12095	COG1570	exodeoxyribonuclease VII activity
HFD83_12145	COG0583	DNA-binding transcription factor activity
HFD83_12150	COG4638	Rieske (2fe-2S)
HFD83_12155	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HFD83_12160	COG0633	Ferredoxin
HFD83_12160	COG0543	2 iron, 2 sulfur cluster binding
HFD83_12165	COG1028	Short-chain dehydrogenase reductase Sdr
HFD83_12170	COG3135	benzoate transporter
HFD83_12175	COG2814	Major facilitator Superfamily
HFD83_12190	COG1643	Atp-dependent helicase
HFD83_12195	COG0450	alkyl hydroperoxide reductase
HFD83_12205	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HFD83_12215	COG3634	alkyl hydroperoxide reductase activity
HFD83_12235	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HFD83_12240	COG0625	glutathione transferase activity
HFD83_12250	COG2885	chlorophyll binding
HFD83_12285	COG0542	response to heat
HFD83_12300	COG1765	OsmC-like protein
HFD83_12315	COG0667	Aldo Keto reductase
HFD83_12330	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HFD83_12340	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HFD83_12350	COG0527	aspartate kinase activity
HFD83_12360	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFD83_12370	COG3038	cytochrome b561
HFD83_12375	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HFD83_12380	COG2252	PERMEase
HFD83_12390	COG2072	flavoprotein involved in K transport
HFD83_12405	COG1741	Belongs to the pirin family
HFD83_12410	COG1309	transcriptional regulator
HFD83_12420	COG0300	oxidoreductase activity
HFD83_12525	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HFD83_12555	COG1113	amino acid transport
HFD83_12575	COG1012	belongs to the aldehyde dehydrogenase family
HFD83_12595	COG0531	amino acid
HFD83_12605	COG1113	amino acid transport
HFD83_12645	COG3209	COG3209 Rhs family protein
HFD83_12650	COG3501	Rhs element vgr protein
HFD83_12675	COG4269	membrane
HFD83_12690	COG0446	pyridine nucleotide-disulphide oxidoreductase
HFD83_12690	COG1902	pentaerythritol trinitrate reductase activity
HFD83_12700	COG3706	GGDEF domain
HFD83_12700	COG4251	negative regulation of phosphorylation
HFD83_12700	COG5001	Diguanylate cyclase
HFD83_12700	COG2203	Gaf domain
HFD83_12710	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HFD83_12730	COG4172	Belongs to the ABC transporter superfamily
HFD83_12735	COG4239	(ABC) transporter, permease
HFD83_12740	COG4174	ABC transporter (Permease)
HFD83_12750	COG1388	LysM domain
HFD83_12750	COG0741	lytic transglycosylase activity
HFD83_12750	COG0741	lytic transglycosylase activity
HFD83_12750	COG1388	LysM domain
HFD83_12755	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HFD83_12795	COG0583	DNA-binding transcription factor activity
HFD83_12800	COG1279	arginine transmembrane transporter activity
HFD83_12820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HFD83_12825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HFD83_12830	COG0006	proline dipeptidase activity
HFD83_12915	COG0739	heme binding
HFD83_12915	COG1196	nuclear chromosome segregation
HFD83_12915	COG0741	lytic transglycosylase activity
HFD83_12975	COG4695	Portal protein
HFD83_13070	COG0305	Participates in initiation and elongation during chromosome replication
HFD83_13085	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HFD83_13135	COG2194	sulfuric ester hydrolase activity
HFD83_13180	COG0739	heme binding
HFD83_13505	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HFD83_13530	COG3384	dioxygenase
HFD83_13540	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HFD83_13545	COG2878	Part of a membrane complex involved in electron transport
HFD83_13550	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HFD83_13575	COG0768	penicillin binding
HFD83_13580	COG0742	ribosomal rna small subunit methyltransferase
HFD83_13595	COG0830	nickel cation binding
HFD83_13605	COG0804	urea catabolic process
HFD83_13645	COG1253	flavin adenine dinucleotide binding
HFD83_13650	COG2851	Citrate transporter
HFD83_13700	COG1773	rubredoxin
HFD83_13705	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HFD83_13715	COG0583	DNA-binding transcription factor activity
HFD83_13740	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HFD83_13745	COG4181	ATPase activity
HFD83_13790	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HFD83_13810	COG0306	phosphate transporter
HFD83_13820	COG3958	Transketolase
HFD83_13825	COG3959	Transketolase, thiamine diphosphate binding domain
HFD83_13830	COG2271	Major facilitator Superfamily
HFD83_13835	COG1028	Short-chain dehydrogenase reductase Sdr
HFD83_13840	COG0583	DNA-binding transcription factor activity
HFD83_13855	COG2223	nitrite transmembrane transporter activity
HFD83_13860	COG2207	Transcriptional regulator
HFD83_13865	COG2066	Belongs to the glutaminase family
HFD83_13870	COG0242	peptide deformylase activity
HFD83_13875	COG0477	Major facilitator Superfamily
HFD83_13885	COG0028	Belongs to the TPP enzyme family
HFD83_13900	COG1028	Short-chain dehydrogenase reductase Sdr
HFD83_13905	COG2267	carboxylic ester hydrolase activity
HFD83_13915	COG2271	Major facilitator Superfamily
HFD83_13920	COG0446	pyridine nucleotide-disulphide oxidoreductase
HFD83_13930	COG1028	Short-chain dehydrogenase reductase Sdr
HFD83_13950	COG1414	Transcriptional regulator
HFD83_13965	COG1024	Enoyl-CoA hydratase
HFD83_13975	COG1215	transferase activity, transferring glycosyl groups
HFD83_13980	COG0726	polysaccharide deacetylase
HFD83_13980	COG1649	PFAM Uncharacterised BCR, COG1649
HFD83_13990	COG4681	YaeQ
HFD83_14000	COG0523	cobalamin synthesis protein
HFD83_14010	COG1607	acyl-coa hydrolase
HFD83_14020	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HFD83_14025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HFD83_14030	COG1309	transcriptional regulator
HFD83_14055	COG2040	homocysteine
HFD83_14060	COG0531	amino acid
HFD83_14115	COG1595	DNA-templated transcription, initiation
HFD83_14125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HFD83_14130	COG0477	Major facilitator Superfamily
HFD83_14150	COG0084	hydrolase, TatD family'
HFD83_14185	COG0629	single-stranded DNA binding
HFD83_14240	COG0582	viral genome integration into host DNA
HFD83_14260	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HFD83_14345	COG0592	DNA-directed DNA polymerase activity
HFD83_14385	COG2026	Addiction module toxin, RelE StbE family
HFD83_14580	COG1484	DNA-dependent DNA replication
HFD83_14695	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HFD83_14730	COG0405	Gamma-glutamyltransferase
HFD83_14735	COG2814	Major facilitator Superfamily
HFD83_14745	COG2050	protein possibly involved in aromatic compounds catabolism
HFD83_14760	COG1090	epimerase
HFD83_14780	COG0420	3'-5' exonuclease activity
HFD83_14805	COG0735	belongs to the Fur family
HFD83_14810	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HFD83_14830	COG0121	glutamine amidotransferase
HFD83_14845	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HFD83_14855	COG0210	DNA helicase
HFD83_14860	COG2885	chlorophyll binding
HFD83_14865	COG0204	Acyl-transferase
HFD83_14880	COG2894	cell division
HFD83_14900	COG1280	lysine exporter protein (LysE YggA)
HFD83_14905	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HFD83_14905	COG1674	ftsk spoiiie
HFD83_14910	COG0492	ferredoxin-NADP+ reductase activity
HFD83_14915	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HFD83_14925	COG0456	acetyltransferase
HFD83_14985	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HFD83_14985	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HFD83_15005	COG1012	belongs to the aldehyde dehydrogenase family
HFD83_15025	COG0473	3-isopropylmalate dehydrogenase activity
HFD83_15030	COG0583	DNA-binding transcription factor activity
HFD83_15050	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HFD83_15075	COG0564	pseudouridine synthase activity
HFD83_15085	COG0358	DNA primase activity
HFD83_15100	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HFD83_15130	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFD83_15160	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HFD83_15170	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HFD83_15170	COG0352	thiamine-phosphate diphosphorylase activity
HFD83_15170	COG0351	phosphomethylpyrimidine kinase
HFD83_15180	COG1652	LysM domain
HFD83_15205	COG1399	metal-binding, possibly nucleic acid-binding protein
HFD83_15210	COG3101	peptidyl-lysine hydroxylation
HFD83_15215	COG0009	L-threonylcarbamoyladenylate synthase
HFD83_15220	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HFD83_15225	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HFD83_15240	COG4106	trans-aconitate 2-methyltransferase activity
HFD83_15255	COG0596	Alpha beta hydrolase
HFD83_15255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HFD83_15255	COG2226	methyltransferase
HFD83_15260	COG1877	trehalose-phosphatase activity
HFD83_15265	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HFD83_15270	COG2223	nitrite transmembrane transporter activity
HFD83_15290	COG1196	nuclear chromosome segregation
HFD83_15300	COG0730	response to heat
HFD83_15315	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HFD83_15325	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HFD83_15375	COG0489	protein tyrosine kinase activity
HFD83_15385	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HFD83_15385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HFD83_15415	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HFD83_15420	COG2081	HI0933 family
HFD83_15430	COG0668	transmembrane transport
HFD83_15450	COG0583	DNA-binding transcription factor activity
HFD83_15470	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HFD83_15475	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HFD83_15505	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HFD83_15540	COG2205	protein histidine kinase activity
HFD83_15545	COG0745	RESPONSE REGULATOR receiver
HFD83_15565	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFD83_15575	COG2205	protein histidine kinase activity
HFD83_15645	COG4993	Dehydrogenase
HFD83_15665	COG0384	phenazine biosynthesis protein PhzF
HFD83_15685	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HFD83_15700	COG0583	DNA-binding transcription factor activity
HFD83_15720	COG1473	amidohydrolase
HFD83_15730	COG0583	DNA-binding transcription factor activity
HFD83_15745	COG0583	DNA-binding transcription factor activity
HFD83_15750	COG1053	succinate dehydrogenase
HFD83_15760	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HFD83_15765	COG2814	Major facilitator Superfamily
HFD83_15770	COG1960	acyl-CoA dehydrogenase activity
HFD83_15775	COG0583	DNA-binding transcription factor activity
HFD83_15780	COG1063	alcohol dehydrogenase
HFD83_15810	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HFD83_15815	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HFD83_15820	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HFD83_15835	COG3667	copper resistance
HFD83_15840	COG2132	Multicopper oxidase
HFD83_15850	COG0561	phosphatase activity
HFD83_15855	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HFD83_15880	COG1214	PFAM Peptidase M22, glycoprotease
HFD83_15930	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HFD83_15940	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HFD83_15945	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HFD83_15950	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HFD83_16010	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HFD83_16020	COG1846	Transcriptional regulator
HFD83_16025	COG1764	response to oxidative stress
HFD83_16065	COG0037	tRNA processing
HFD83_16075	COG0248	Ppx GppA phosphatase
HFD83_16105	COG0072	phenylalanine-tRNA ligase activity
HFD83_16145	COG1238	metal cluster binding
HFD83_16150	COG0625	glutathione transferase activity
HFD83_16165	COG0318	PFAM AMP-dependent synthetase and ligase
HFD83_16170	COG3028	Belongs to the UPF0307 family
HFD83_16175	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HFD83_16195	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HFD83_16200	COG0617	tRNA 3'-terminal CCA addition
HFD83_16205	COG1555	photosystem II stabilization
HFD83_16210	COG3956	TIGRFAM MazG family protein
HFD83_16220	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HFD83_16240	COG5002	protein histidine kinase activity
HFD83_16240	COG2205	protein histidine kinase activity
HFD83_16240	COG0784	Response regulator, receiver
HFD83_16245	COG1024	Enoyl-CoA hydratase
HFD83_16250	COG2084	Dehydrogenase
HFD83_16255	COG3622	Belongs to the hyi family
HFD83_16285	COG0697	spore germination
HFD83_16295	COG2814	Major facilitator Superfamily
HFD83_16300	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HFD83_16310	COG0583	DNA-binding transcription factor activity
HFD83_16320	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HFD83_16335	COG0084	hydrolase, TatD family'
HFD83_16350	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HFD83_16380	COG0440	acetolactate synthase activity
HFD83_16385	COG0028	Belongs to the TPP enzyme family
HFD83_16410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HFD83_16415	COG0577	efflux transmembrane transporter activity
HFD83_16415	COG1136	(ABC) transporter
HFD83_16420	COG1538	Outer membrane efflux protein
HFD83_16435	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HFD83_16440	COG1162	GTPase activity
HFD83_16450	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HFD83_16470	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HFD83_16475	COG1028	Short-chain dehydrogenase reductase Sdr
HFD83_16515	COG2986	histidine ammonia-lyase
HFD83_16530	COG0318	PFAM AMP-dependent synthetase and ligase
HFD83_16540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFD83_16585	COG1426	Protein conserved in bacteria
HFD83_16620	COG0793	Belongs to the peptidase S41A family
HFD83_16635	COG2267	carboxylic ester hydrolase activity
HFD83_16645	COG1012	belongs to the aldehyde dehydrogenase family
HFD83_16650	COG3265	gluconokinase activity
HFD83_16660	COG0800	Aldolase
HFD83_16670	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFD83_16675	COG0857	belongs to the CobB CobQ family
HFD83_16675	COG0280	phosphate acetyltransferase
HFD83_16680	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HFD83_16680	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HFD83_16700	COG0740	serine-type endopeptidase activity
HFD83_16710	COG4774	siderophore transport
HFD83_16720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HFD83_16730	COG2813	Specifically methylates the guanine in position
HFD83_16730	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HFD83_16830	COG0788	formyltetrahydrofolate deformylase activity
HFD83_16855	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HFD83_16855	COG4651	solute:proton antiporter activity
HFD83_16875	COG0724	RNA recognition motif
HFD83_16880	COG0210	DNA helicase
HFD83_16905	COG1733	regulation of RNA biosynthetic process
HFD83_16915	COG2900	Belongs to the SlyX family
HFD83_16925	COG1280	lysine exporter protein (LysE YggA)
HFD83_16930	COG1560	Kdo2-lipid A biosynthetic process
HFD83_16940	COG1301	dicarboxylic acid transport
HFD83_16995	COG0473	3-isopropylmalate dehydrogenase activity
HFD83_17060	COG0583	DNA-binding transcription factor activity
HFD83_17070	COG0625	glutathione transferase activity
HFD83_17075	COG2378	regulation of single-species biofilm formation
HFD83_17080	COG0546	phosphoglycolate phosphatase activity
HFD83_17095	COG1530	ribonuclease E activity
HFD83_17100	COG0318	PFAM AMP-dependent synthetase and ligase
HFD83_17115	COG0583	DNA-binding transcription factor activity
HFD83_17120	COG4221	oxidoreductase activity
HFD83_17125	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HFD83_17135	COG0534	Mate efflux family protein
HFD83_17150	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HFD83_17190	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HFD83_17195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HFD83_17210	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HFD83_17220	COG0644	oxidoreductase
HFD83_17220	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HFD83_17225	COG0425	Belongs to the sulfur carrier protein TusA family
HFD83_17230	COG4535	Mg2 and Co2 transporter CorC
HFD83_17240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HFD83_17260	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HFD83_17265	COG0475	glutathione-regulated potassium exporter activity
HFD83_17265	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HFD83_17270	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HFD83_17280	COG0484	heat shock protein binding
HFD83_17285	COG0789	Transcriptional regulator
HFD83_17290	COG0598	Magnesium transport protein CorA
HFD83_17310	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HFD83_17315	COG1074	ATP-dependent DNA helicase activity
HFD83_17320	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HFD83_17340	COG2226	methyltransferase
HFD83_17355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HFD83_17360	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HFD83_17375	COG2111	Na H antiporter
HFD83_17375	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HFD83_17380	COG1006	Multisubunit Na H antiporter MnhC subunit
HFD83_17385	COG0651	ATP synthesis coupled electron transport
HFD83_17395	COG2212	antiporter activity
HFD83_17415	COG0195	Participates in both transcription termination and antitermination
HFD83_17465	COG0237	dephospho-CoA kinase activity
HFD83_17475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFD83_17490	COG0497	DNA recombination
HFD83_17500	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HFD83_17530	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HFD83_17530	COG2169	Transcriptional regulator
HFD83_17535	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HFD83_17600	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HFD83_17615	COG0326	Molecular chaperone. Has ATPase activity
HFD83_17630	COG2056	Na+-H+ antiporter family
HFD83_17635	COG0596	Alpha beta hydrolase
HFD83_17730	COG0546	phosphoglycolate phosphatase activity
HFD83_17735	COG1716	ATPase activity
HFD83_17780	COG0181	hydroxymethylbilane synthase activity
HFD83_17790	COG3275	phosphorelay sensor kinase activity
HFD83_17810	COG1538	Outer membrane efflux protein
HFD83_17815	COG0697	spore germination
HFD83_17840	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HFD83_17845	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HFD83_17850	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HFD83_17855	COG0772	Belongs to the SEDS family
HFD83_17880	COG4974	Belongs to the 'phage' integrase family
HFD83_17885	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HFD83_17895	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HFD83_17905	COG2197	response regulator
HFD83_17920	COG0793	Belongs to the peptidase S41A family
HFD83_17925	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HFD83_17930	COG0795	lipopolysaccharide-transporting ATPase activity
HFD83_17970	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HFD83_17970	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HFD83_17980	COG0004	ammonium transporteR
HFD83_17985	COG0347	Belongs to the P(II) protein family
HFD83_17995	COG0606	chelatase, subunit chli
HFD83_18065	COG0659	secondary active sulfate transmembrane transporter activity
HFD83_18070	COG0589	response to stress
HFD83_18110	COG0606	chelatase, subunit chli
HFD83_18115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HFD83_18125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HFD83_18140	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HFD83_18155	COG0318	PFAM AMP-dependent synthetase and ligase
HFD83_18165	COG0477	Major facilitator Superfamily
HFD83_18170	COG2860	membrane
HFD83_18180	COG1253	flavin adenine dinucleotide binding
HFD83_18200	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HFD83_18235	COG0655	NAD(P)H dehydrogenase (quinone) activity
HFD83_18245	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HFD83_18280	COG1309	transcriptional regulator
HFD83_18315	COG0758	DNA mediated transformation
HFD83_18325	COG0697	spore germination
HFD83_18330	COG1309	transcriptional regulator
HFD83_18345	COG0386	Belongs to the glutathione peroxidase family
HFD83_18410	COG1121	(ABC) transporter
HFD83_18415	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HFD83_18420	COG1280	lysine exporter protein (LysE YggA)
HFD83_18425	COG2837	iron assimilation
HFD83_18435	COG0281	malic enzyme
HFD83_18480	COG0519	Catalyzes the synthesis of GMP from XMP
HFD83_18480	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HFD83_18485	COG4399	Belongs to the UPF0754 family
HFD83_18490	COG2259	Doxx family
HFD83_18495	COG0586	Pfam SNARE associated Golgi protein
HFD83_18510	COG1192	Involved in chromosome partitioning
HFD83_18520	COG0271	Belongs to the BolA IbaG family
HFD83_18540	COG2267	carboxylic ester hydrolase activity
HFD83_18560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFD83_18560	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HFD83_18560	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HFD83_18560	COG3321	synthase
HFD83_18565	COG1960	acyl-CoA dehydrogenase activity
HFD83_18575	COG2197	response regulator
HFD83_18585	COG3916	Acyl-homoserine-lactone synthase
HFD83_18590	COG0477	Major facilitator Superfamily
HFD83_18595	COG1024	Enoyl-CoA hydratase
HFD83_18600	COG1024	Enoyl-CoA hydratase
HFD83_18605	COG1960	acyl-CoA dehydrogenase activity
HFD83_18610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HFD83_18630	COG1113	amino acid transport
HFD83_18635	COG1113	amino acid transport
HFD83_18640	COG0251	oxidation-reduction process
HFD83_18680	COG0564	pseudouridine synthase activity
HFD83_18740	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HFD83_18755	COG1802	Transcriptional regulator
HFD83_18765	COG1448	Aminotransferase
HFD83_18770	COG0277	FAD linked oxidase domain protein
HFD83_18780	COG2186	Transcriptional regulator
HFD83_18790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HFD83_18800	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HFD83_18815	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HFD83_18820	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HFD83_18840	COG1215	transferase activity, transferring glycosyl groups
HFD83_18850	COG0438	transferase activity, transferring glycosyl groups
HFD83_18875	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HFD83_18880	COG1596	polysaccharide export
HFD83_18905	COG0728	peptidoglycan biosynthetic process
HFD83_18910	COG3023	N-Acetylmuramoyl-L-alanine amidase
HFD83_18965	COG0546	phosphoglycolate phosphatase activity
HFD83_18970	COG1028	Short-chain dehydrogenase reductase Sdr
HFD83_18990	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HFD83_18995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HFD83_19000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HFD83_19005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HFD83_19010	COG1116	anion transmembrane transporter activity
HFD83_19015	COG1309	transcriptional regulator
HFD83_19020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HFD83_19030	COG0196	riboflavin kinase activity
HFD83_19035	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HFD83_19045	COG1047	Peptidyl-prolyl cis-trans
HFD83_19085	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HFD83_19140	COG2951	lytic endotransglycosylase activity
HFD83_19145	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HFD83_19160	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HFD83_19170	COG0671	phosphoesterase, PA-phosphatase related
HFD83_19175	COG0861	Integral membrane protein TerC family
HFD83_19185	COG0754	glutathionylspermidine amidase activity
HFD83_19195	COG0402	S-adenosylhomocysteine deaminase activity
HFD83_19210	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HFD83_19215	COG1230	cation diffusion facilitator family transporter
HFD83_19230	COG0706	membrane insertase activity
HFD83_19300	COG1525	nuclease
HFD83_19365	COG1475	DNA binding
HFD83_19380	COG3853	Toxic anion resistance protein (TelA)
HFD83_19515	COG3328	transposase activity
HFD83_19565	COG0741	lytic transglycosylase activity
HFD83_19600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process