locus-tag	class	description
FR761_00005	COG0668	transmembrane transport
FR761_00010	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FR761_00015	COG1519	Transferase
FR761_00020	COG1902	pentaerythritol trinitrate reductase activity
FR761_00040	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FR761_00065	COG0426	domain, Protein
FR761_00065	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FR761_00070	COG4774	siderophore transport
FR761_00075	COG2119	membrane
FR761_00085	COG0508	dehydrogenase complex catalyzes the overall conversion of
FR761_00095	COG4942	peptidase
FR761_00110	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FR761_00120	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FR761_00140	COG0189	ligase activity
FR761_00160	COG0708	Exodeoxyribonuclease III
FR761_00165	COG1393	Belongs to the ArsC family
FR761_00180	COG3706	GGDEF domain
FR761_00215	COG2351	hydroxyisourate hydrolase activity
FR761_00220	COG2233	PERMEase
FR761_00230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FR761_00240	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FR761_00250	COG3150	esterase
FR761_00325	COG3501	Rhs element vgr protein
FR761_00335	COG2918	glutathione biosynthetic process
FR761_00350	COG2733	membrane
FR761_00355	COG0436	Aminotransferase
FR761_00360	COG0534	Mate efflux family protein
FR761_00455	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FR761_00460	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FR761_00470	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FR761_00515	COG1002	Type II restriction enzyme, methylase subunits
FR761_00520	COG1061	Type III restriction enzyme res subunit
FR761_00530	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FR761_00545	COG3328	transposase activity
FR761_00575	COG1078	dGTPase activity
FR761_00590	COG3293	Transposase
FR761_00620	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FR761_00625	COG0546	phosphoglycolate phosphatase activity
FR761_00640	COG2826	transposase and inactivated derivatives, IS30 family
FR761_00680	COG0010	Belongs to the arginase family
FR761_00710	COG2188	Transcriptional regulator
FR761_00720	COG0523	cobalamin synthesis protein
FR761_00730	COG1113	amino acid transport
FR761_00740	COG0625	glutathione transferase activity
FR761_00760	COG1683	Conserved Protein
FR761_00765	COG0534	Mate efflux family protein
FR761_00770	COG0385	Bile acid
FR761_00775	COG1335	isochorismatase
FR761_00780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FR761_00800	COG2116	formate transmembrane transporter activity
FR761_00805	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FR761_00810	COG2133	pyrroloquinoline quinone binding
FR761_00815	COG2983	Belongs to the UPF0260 family
FR761_00835	COG1194	a g-specific adenine glycosylase
FR761_00850	COG2818	Glycosylase
FR761_00855	COG1064	alcohol dehydrogenase
FR761_00860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FR761_00875	COG0583	DNA-binding transcription factor activity
FR761_00885	COG2814	Major facilitator Superfamily
FR761_00920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR761_00935	COG2233	PERMEase
FR761_00940	COG0583	DNA-binding transcription factor activity
FR761_00975	COG0733	neurotransmitter:sodium symporter activity
FR761_00980	COG3293	Transposase
FR761_01020	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FR761_01090	COG2951	lytic endotransglycosylase activity
FR761_01095	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FR761_01115	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FR761_01125	COG0671	phosphoesterase, PA-phosphatase related
FR761_01130	COG0861	Integral membrane protein TerC family
FR761_01145	COG0754	glutathionylspermidine amidase activity
FR761_01155	COG0402	S-adenosylhomocysteine deaminase activity
FR761_01170	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FR761_01175	COG1230	cation diffusion facilitator family transporter
FR761_01190	COG0706	membrane insertase activity
FR761_01205	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FR761_01215	COG0592	DNA-directed DNA polymerase activity
FR761_01225	COG0187	DNA topoisomerase II activity
FR761_01235	COG0586	Pfam SNARE associated Golgi protein
FR761_01240	COG0488	(ABC) transporter
FR761_01265	COG0596	Alpha beta hydrolase
FR761_01270	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FR761_01275	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FR761_01320	COG3293	Transposase
FR761_01325	COG1047	Peptidyl-prolyl cis-trans
FR761_01335	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FR761_01340	COG0196	riboflavin kinase activity
FR761_01350	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FR761_01355	COG1309	transcriptional regulator
FR761_01360	COG1116	anion transmembrane transporter activity
FR761_01365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FR761_01370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FR761_01375	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FR761_01380	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FR761_01400	COG1028	Short-chain dehydrogenase reductase Sdr
FR761_01405	COG0546	phosphoglycolate phosphatase activity
FR761_01475	COG3023	N-Acetylmuramoyl-L-alanine amidase
FR761_01480	COG0728	peptidoglycan biosynthetic process
FR761_01505	COG1596	polysaccharide export
FR761_01510	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FR761_01520	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FR761_01535	COG2244	polysaccharide biosynthetic process
FR761_01540	COG0463	Glycosyl transferase, family 2
FR761_01540	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FR761_01545	COG0463	Glycosyl transferase, family 2
FR761_01545	COG1216	Glycosyl transferase, family 2
FR761_01555	COG0438	transferase activity, transferring glycosyl groups
FR761_01565	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FR761_01570	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FR761_01585	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FR761_01595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FR761_01605	COG2186	Transcriptional regulator
FR761_01615	COG0277	FAD linked oxidase domain protein
FR761_01620	COG1448	Aminotransferase
FR761_01630	COG1802	Transcriptional regulator
FR761_01645	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FR761_01680	COG0564	pseudouridine synthase activity
FR761_01705	COG1522	sequence-specific DNA binding
FR761_01725	COG2267	carboxylic ester hydrolase activity
FR761_01745	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FR761_01805	COG1538	Outer membrane efflux protein
FR761_01810	COG1132	(ABC) transporter
FR761_01825	COG4115	mRNA cleavage
FR761_01835	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FR761_01840	COG3550	peptidyl-serine autophosphorylation
FR761_01890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR761_01895	COG1129	ABC transporter
FR761_01895	COG0842	Transport permease protein
FR761_01900	COG0842	Transport permease protein
FR761_01905	COG1283	sodium-dependent phosphate transmembrane transporter activity
FR761_01930	COG3756	Protein conserved in bacteria
FR761_01965	COG0271	Belongs to the BolA IbaG family
FR761_01990	COG0586	Pfam SNARE associated Golgi protein
FR761_01995	COG2259	Doxx family
FR761_02000	COG4399	Belongs to the UPF0754 family
FR761_02005	COG0519	Catalyzes the synthesis of GMP from XMP
FR761_02005	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FR761_02050	COG0281	malic enzyme
FR761_02055	COG2837	iron assimilation
FR761_02060	COG1280	lysine exporter protein (LysE YggA)
FR761_02065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FR761_02070	COG1121	(ABC) transporter
FR761_02135	COG0386	Belongs to the glutathione peroxidase family
FR761_02150	COG1309	transcriptional regulator
FR761_02155	COG0697	spore germination
FR761_02165	COG0758	DNA mediated transformation
FR761_02215	COG1309	transcriptional regulator
FR761_02250	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FR761_02260	COG0655	NAD(P)H dehydrogenase (quinone) activity
FR761_02295	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FR761_02325	COG1253	flavin adenine dinucleotide binding
FR761_02330	COG3012	SEC-C Motif Domain Protein
FR761_02335	COG2860	membrane
FR761_02340	COG0477	Major facilitator Superfamily
FR761_02350	COG0318	PFAM AMP-dependent synthetase and ligase
FR761_02365	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FR761_02380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FR761_02390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FR761_02395	COG0606	chelatase, subunit chli
FR761_02405	COG0347	Belongs to the P(II) protein family
FR761_02410	COG0004	ammonium transporteR
FR761_02420	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FR761_02420	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FR761_02460	COG0795	lipopolysaccharide-transporting ATPase activity
FR761_02465	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FR761_02470	COG0793	Belongs to the peptidase S41A family
FR761_02485	COG2197	response regulator
FR761_02495	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FR761_02505	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FR761_02510	COG4974	Belongs to the 'phage' integrase family
FR761_02535	COG0772	Belongs to the SEDS family
FR761_02540	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FR761_02545	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FR761_02550	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FR761_02575	COG0697	spore germination
FR761_02580	COG1538	Outer membrane efflux protein
FR761_02600	COG3275	phosphorelay sensor kinase activity
FR761_02610	COG0181	hydroxymethylbilane synthase activity
FR761_02655	COG1716	ATPase activity
FR761_02660	COG0546	phosphoglycolate phosphatase activity
FR761_02755	COG0596	Alpha beta hydrolase
FR761_02760	COG2056	Na+-H+ antiporter family
FR761_02775	COG0326	Molecular chaperone. Has ATPase activity
FR761_02790	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FR761_02865	COG2826	transposase and inactivated derivatives, IS30 family
FR761_02875	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FR761_02880	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FR761_02880	COG2169	Transcriptional regulator
FR761_02910	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FR761_02920	COG0497	DNA recombination
FR761_02935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FR761_02945	COG0237	dephospho-CoA kinase activity
FR761_02995	COG0195	Participates in both transcription termination and antitermination
FR761_03015	COG2212	antiporter activity
FR761_03025	COG0651	ATP synthesis coupled electron transport
FR761_03030	COG1006	Multisubunit Na H antiporter MnhC subunit
FR761_03035	COG2111	Na H antiporter
FR761_03035	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FR761_03050	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FR761_03085	COG2226	methyltransferase
FR761_03105	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FR761_03110	COG1074	ATP-dependent DNA helicase activity
FR761_03115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FR761_03135	COG0598	Magnesium transport protein CorA
FR761_03140	COG0789	Transcriptional regulator
FR761_03145	COG0484	heat shock protein binding
FR761_03160	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FR761_03160	COG0475	glutathione-regulated potassium exporter activity
FR761_03165	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FR761_03185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FR761_03195	COG4535	Mg2 and Co2 transporter CorC
FR761_03200	COG0425	Belongs to the sulfur carrier protein TusA family
FR761_03210	COG0644	oxidoreductase
FR761_03210	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FR761_03220	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FR761_03235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FR761_03240	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FR761_03275	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FR761_03290	COG0534	Mate efflux family protein
FR761_03300	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FR761_03305	COG4221	oxidoreductase activity
FR761_03310	COG0583	DNA-binding transcription factor activity
FR761_03330	COG1530	ribonuclease E activity
FR761_03345	COG0546	phosphoglycolate phosphatase activity
FR761_03350	COG2378	regulation of single-species biofilm formation
FR761_03365	COG0583	DNA-binding transcription factor activity
FR761_03395	COG0583	DNA-binding transcription factor activity
FR761_03420	COG0473	3-isopropylmalate dehydrogenase activity
FR761_03475	COG1301	dicarboxylic acid transport
FR761_03485	COG1560	Kdo2-lipid A biosynthetic process
FR761_03490	COG1280	lysine exporter protein (LysE YggA)
FR761_03515	COG1733	regulation of RNA biosynthetic process
FR761_03540	COG0210	DNA helicase
FR761_03545	COG0724	RNA recognition motif
FR761_03565	COG4651	solute:proton antiporter activity
FR761_03565	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FR761_03570	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FR761_03575	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FR761_03590	COG0788	formyltetrahydrofolate deformylase activity
FR761_03690	COG2813	Specifically methylates the guanine in position
FR761_03690	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FR761_03700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FR761_03710	COG4774	siderophore transport
FR761_03720	COG0740	serine-type endopeptidase activity
FR761_03740	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FR761_03740	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FR761_03745	COG0280	phosphate acetyltransferase
FR761_03745	COG0857	belongs to the CobB CobQ family
FR761_03750	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FR761_03760	COG0800	Aldolase
FR761_03770	COG3265	gluconokinase activity
FR761_03775	COG1012	belongs to the aldehyde dehydrogenase family
FR761_03785	COG2267	carboxylic ester hydrolase activity
FR761_03800	COG0793	Belongs to the peptidase S41A family
FR761_03835	COG1426	Protein conserved in bacteria
FR761_03875	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FR761_03885	COG1162	GTPase activity
FR761_03890	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FR761_03905	COG1538	Outer membrane efflux protein
FR761_03910	COG0577	efflux transmembrane transporter activity
FR761_03910	COG1136	(ABC) transporter
FR761_03915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR761_03940	COG0028	Belongs to the TPP enzyme family
FR761_03945	COG0440	acetolactate synthase activity
FR761_03980	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FR761_03995	COG0084	hydrolase, TatD family'
FR761_04005	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FR761_04015	COG0583	DNA-binding transcription factor activity
FR761_04025	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FR761_04100	COG2826	transposase and inactivated derivatives, IS30 family
FR761_04125	COG2205	protein histidine kinase activity
FR761_04140	COG2132	Multicopper oxidase
FR761_04165	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FR761_04220	COG2814	Major facilitator Superfamily
FR761_04230	COG0697	spore germination
FR761_04235	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FR761_04240	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FR761_04245	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FR761_04260	COG3622	Belongs to the hyi family
FR761_04265	COG2084	Dehydrogenase
FR761_04270	COG1024	Enoyl-CoA hydratase
FR761_04275	COG2205	protein histidine kinase activity
FR761_04275	COG5002	protein histidine kinase activity
FR761_04275	COG0784	Response regulator, receiver
FR761_04295	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FR761_04305	COG3956	TIGRFAM MazG family protein
FR761_04310	COG1555	photosystem II stabilization
FR761_04315	COG0617	tRNA 3'-terminal CCA addition
FR761_04320	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FR761_04340	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR761_04345	COG3028	Belongs to the UPF0307 family
FR761_04350	COG0318	PFAM AMP-dependent synthetase and ligase
FR761_04370	COG0625	glutathione transferase activity
FR761_04375	COG1238	metal cluster binding
FR761_04390	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FR761_04415	COG0072	phenylalanine-tRNA ligase activity
FR761_04445	COG0248	Ppx GppA phosphatase
FR761_04455	COG0037	tRNA processing
FR761_04495	COG1764	response to oxidative stress
FR761_04500	COG1846	Transcriptional regulator
FR761_04510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FR761_04570	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FR761_04575	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FR761_04580	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FR761_04590	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FR761_04625	COG1214	PFAM Peptidase M22, glycoprotease
FR761_04650	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FR761_04655	COG0561	phosphatase activity
FR761_04685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FR761_04690	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FR761_04695	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FR761_04725	COG1063	alcohol dehydrogenase
FR761_04730	COG0583	DNA-binding transcription factor activity
FR761_04735	COG1960	acyl-CoA dehydrogenase activity
FR761_04740	COG2814	Major facilitator Superfamily
FR761_04745	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FR761_04750	COG1309	transcriptional regulator
FR761_04765	COG1053	succinate dehydrogenase
FR761_04770	COG0583	DNA-binding transcription factor activity
FR761_04800	COG3293	Transposase
FR761_04815	COG0583	DNA-binding transcription factor activity
FR761_04825	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FR761_04830	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FR761_04865	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FR761_04885	COG0745	RESPONSE REGULATOR receiver
FR761_04890	COG2205	protein histidine kinase activity
FR761_04900	COG3706	GGDEF domain
FR761_04925	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FR761_04955	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FR761_04960	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FR761_04980	COG0583	DNA-binding transcription factor activity
FR761_05000	COG0668	transmembrane transport
FR761_05010	COG2081	HI0933 family
FR761_05015	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FR761_05045	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FR761_05045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FR761_05055	COG0489	protein tyrosine kinase activity
FR761_05115	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FR761_05125	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FR761_05140	COG0730	response to heat
FR761_05150	COG1196	nuclear chromosome segregation
FR761_05170	COG2223	nitrite transmembrane transporter activity
FR761_05175	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FR761_05180	COG1877	trehalose-phosphatase activity
FR761_05185	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FR761_05185	COG0596	Alpha beta hydrolase
FR761_05185	COG2226	methyltransferase
FR761_05200	COG4106	trans-aconitate 2-methyltransferase activity
FR761_05215	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FR761_05220	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FR761_05225	COG0009	L-threonylcarbamoyladenylate synthase
FR761_05230	COG3101	peptidyl-lysine hydroxylation
FR761_05235	COG1399	metal-binding, possibly nucleic acid-binding protein
FR761_05250	COG1028	Short-chain dehydrogenase reductase Sdr
FR761_05260	COG1652	LysM domain
FR761_05265	COG0351	phosphomethylpyrimidine kinase
FR761_05265	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FR761_05265	COG0352	thiamine-phosphate diphosphorylase activity
FR761_05275	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FR761_05305	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FR761_05335	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FR761_05350	COG0358	DNA primase activity
FR761_05360	COG0564	pseudouridine synthase activity
FR761_05385	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FR761_05405	COG0583	DNA-binding transcription factor activity
FR761_05410	COG0473	3-isopropylmalate dehydrogenase activity
FR761_05430	COG1012	belongs to the aldehyde dehydrogenase family
FR761_05450	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FR761_05450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FR761_05510	COG0456	acetyltransferase
FR761_05520	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FR761_05525	COG0492	ferredoxin-NADP+ reductase activity
FR761_05530	COG1674	ftsk spoiiie
FR761_05530	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FR761_05535	COG1280	lysine exporter protein (LysE YggA)
FR761_05550	COG2894	cell division
FR761_05565	COG0204	Acyl-transferase
FR761_05570	COG2885	chlorophyll binding
FR761_05575	COG0210	DNA helicase
FR761_05585	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FR761_05600	COG0121	glutamine amidotransferase
FR761_05625	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FR761_05630	COG0735	belongs to the Fur family
FR761_05655	COG0420	3'-5' exonuclease activity
FR761_05675	COG1090	epimerase
FR761_05690	COG2050	protein possibly involved in aromatic compounds catabolism
FR761_05700	COG2814	Major facilitator Superfamily
FR761_05705	COG0405	Gamma-glutamyltransferase
FR761_05725	COG3328	transposase activity
FR761_05730	COG4681	YaeQ
FR761_05740	COG0726	polysaccharide deacetylase
FR761_05740	COG1649	PFAM Uncharacterised BCR, COG1649
FR761_05745	COG1215	transferase activity, transferring glycosyl groups
FR761_05755	COG1024	Enoyl-CoA hydratase
FR761_05770	COG1414	Transcriptional regulator
FR761_05790	COG1028	Short-chain dehydrogenase reductase Sdr
FR761_05805	COG2271	Major facilitator Superfamily
FR761_05815	COG2267	carboxylic ester hydrolase activity
FR761_05820	COG1028	Short-chain dehydrogenase reductase Sdr
FR761_05835	COG0028	Belongs to the TPP enzyme family
FR761_05845	COG0477	Major facilitator Superfamily
FR761_05850	COG0242	peptide deformylase activity
FR761_05855	COG2066	Belongs to the glutaminase family
FR761_05860	COG2207	Transcriptional regulator
FR761_05865	COG2223	nitrite transmembrane transporter activity
FR761_05885	COG0583	DNA-binding transcription factor activity
FR761_05890	COG1028	Short-chain dehydrogenase reductase Sdr
FR761_05895	COG2271	Major facilitator Superfamily
FR761_05900	COG3959	Transketolase, thiamine diphosphate binding domain
FR761_05905	COG3958	Transketolase
FR761_05915	COG0306	phosphate transporter
FR761_05955	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FR761_05965	COG1061	Type III restriction enzyme res subunit
FR761_05970	COG1002	Type II restriction enzyme, methylase subunits
FR761_05990	COG2963	transposase activity
FR761_06000	COG4372	Transposase
FR761_06070	COG4181	ATPase activity
FR761_06075	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FR761_06105	COG0583	DNA-binding transcription factor activity
FR761_06115	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FR761_06120	COG1773	rubredoxin
FR761_06175	COG2851	Citrate transporter
FR761_06185	COG1253	flavin adenine dinucleotide binding
FR761_06225	COG0804	urea catabolic process
FR761_06235	COG0830	nickel cation binding
FR761_06250	COG0742	ribosomal rna small subunit methyltransferase
FR761_06255	COG0768	penicillin binding
FR761_06280	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FR761_06285	COG2878	Part of a membrane complex involved in electron transport
FR761_06290	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FR761_06300	COG3384	dioxygenase
FR761_06320	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FR761_06360	COG0006	proline dipeptidase activity
FR761_06365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FR761_06370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FR761_06390	COG1279	arginine transmembrane transporter activity
FR761_06395	COG0583	DNA-binding transcription factor activity
FR761_06440	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FR761_06445	COG0741	lytic transglycosylase activity
FR761_06445	COG0741	lytic transglycosylase activity
FR761_06445	COG1388	LysM domain
FR761_06445	COG1388	LysM domain
FR761_06455	COG4174	ABC transporter (Permease)
FR761_06460	COG4239	(ABC) transporter, permease
FR761_06465	COG4172	Belongs to the ABC transporter superfamily
FR761_06485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FR761_06495	COG5001	Diguanylate cyclase
FR761_06495	COG2203	Gaf domain
FR761_06495	COG4251	negative regulation of phosphorylation
FR761_06495	COG3706	GGDEF domain
FR761_06505	COG1902	pentaerythritol trinitrate reductase activity
FR761_06505	COG0446	pyridine nucleotide-disulphide oxidoreductase
FR761_06545	COG1113	amino acid transport
FR761_06555	COG0531	amino acid
FR761_06575	COG1012	belongs to the aldehyde dehydrogenase family
FR761_06595	COG1113	amino acid transport
FR761_06610	COG0697	spore germination
FR761_06615	COG2721	sulfolactate sulfo-lyase activity
FR761_06620	COG2271	Major facilitator Superfamily
FR761_06625	COG4948	Mandelate Racemase Muconate Lactonizing
FR761_06635	COG1012	belongs to the aldehyde dehydrogenase family
FR761_06640	COG2186	Transcriptional regulator
FR761_06665	COG1960	acyl-CoA dehydrogenase activity
FR761_06675	COG1012	belongs to the aldehyde dehydrogenase family
FR761_06680	COG1024	Enoyl-CoA hydratase
FR761_06685	COG2814	Major facilitator Superfamily
FR761_06700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FR761_06715	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FR761_06765	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FR761_06775	COG0583	DNA-binding transcription factor activity
FR761_06780	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FR761_06785	COG2072	flavoprotein involved in K transport
FR761_06790	COG0300	oxidoreductase activity
FR761_06800	COG1309	transcriptional regulator
FR761_06805	COG1741	Belongs to the pirin family
FR761_06820	COG2072	flavoprotein involved in K transport
FR761_06830	COG2252	PERMEase
FR761_06835	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FR761_06845	COG2801	Transposase and inactivated derivatives
FR761_06855	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FR761_06875	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FR761_06885	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FR761_06900	COG0667	Aldo Keto reductase
FR761_06910	COG1765	OsmC-like protein
FR761_06960	COG2885	chlorophyll binding
FR761_06970	COG0625	glutathione transferase activity
FR761_06975	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FR761_06995	COG3634	alkyl hydroperoxide reductase activity
FR761_07005	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FR761_07015	COG0450	alkyl hydroperoxide reductase
FR761_07020	COG1643	Atp-dependent helicase
FR761_07035	COG2814	Major facilitator Superfamily
FR761_07045	COG3135	benzoate transporter
FR761_07050	COG1028	Short-chain dehydrogenase reductase Sdr
FR761_07055	COG0633	Ferredoxin
FR761_07055	COG0543	2 iron, 2 sulfur cluster binding
FR761_07060	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FR761_07065	COG4638	Rieske (2fe-2S)
FR761_07070	COG0583	DNA-binding transcription factor activity
FR761_07080	COG2871	sodium ion transport
FR761_07175	COG1570	exodeoxyribonuclease VII activity
FR761_07210	COG1280	lysine exporter protein (LysE YggA)
FR761_07215	COG1278	Cold shock
FR761_07285	COG0517	IMP dehydrogenase activity
FR761_07285	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FR761_07290	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FR761_07300	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FR761_07305	COG1137	ATPase activity
FR761_07310	COG1538	Outer membrane efflux protein
FR761_07350	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FR761_07385	COG0598	Magnesium transport protein CorA
FR761_07415	COG2801	Transposase and inactivated derivatives
FR761_07435	COG1063	alcohol dehydrogenase
FR761_07450	COG0439	Biotin carboxylase
FR761_07455	COG2249	NAD(P)H dehydrogenase (quinone) activity
FR761_07460	COG1733	regulation of RNA biosynthetic process
FR761_07470	COG0864	Transcriptional regulator
FR761_07480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FR761_07485	COG1116	anion transmembrane transporter activity
FR761_07520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FR761_07540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FR761_07565	COG1012	belongs to the aldehyde dehydrogenase family
FR761_07570	COG0531	amino acid
FR761_07575	COG1760	l-serine dehydratase
FR761_07580	COG2030	dehydratase
FR761_07580	COG1012	belongs to the aldehyde dehydrogenase family
FR761_07585	COG3396	Phenylacetate-CoA oxygenase
FR761_07590	COG3460	Phenylacetate-CoA oxygenase
FR761_07595	COG3396	Phenylacetate-CoA oxygenase
FR761_07600	COG2151	metal-sulfur cluster biosynthetic enzyme
FR761_07605	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FR761_07610	COG1024	Enoyl-CoA hydratase
FR761_07615	COG1024	Enoyl-CoA hydratase
FR761_07620	COG1250	3-hydroxyacyl-CoA dehydrogenase
FR761_07625	COG0183	Belongs to the thiolase family
FR761_07630	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FR761_07635	COG3327	negative regulation of DNA-templated transcription, initiation
FR761_07645	COG2050	protein possibly involved in aromatic compounds catabolism
FR761_07650	COG3209	COG3209 Rhs family protein
FR761_07680	COG1309	transcriptional regulator
FR761_07685	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FR761_07700	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FR761_07705	COG0531	amino acid
FR761_07715	COG0753	catalase activity
FR761_07720	COG3038	cytochrome b561
FR761_07725	COG0583	DNA-binding transcription factor activity
FR761_07735	COG1414	Transcriptional regulator
FR761_07740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FR761_07755	COG1840	ABC-type Fe3 transport system, periplasmic component
FR761_07760	COG3842	ATPase activity
FR761_07775	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FR761_07780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FR761_07785	COG1280	lysine exporter protein (LysE YggA)
FR761_07800	COG0583	DNA-binding transcription factor activity
FR761_07815	COG1024	Enoyl-CoA hydratase
FR761_07820	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FR761_07825	COG1960	acyl-CoA dehydrogenase activity
FR761_07830	COG1309	transcriptional regulator
FR761_07835	COG0318	PFAM AMP-dependent synthetase and ligase
FR761_07855	COG0583	DNA-binding transcription factor activity
FR761_07865	COG2826	transposase and inactivated derivatives, IS30 family
FR761_07880	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FR761_07885	COG2826	transposase and inactivated derivatives, IS30 family
FR761_07915	COG2826	transposase and inactivated derivatives, IS30 family
FR761_07935	COG1028	Short-chain dehydrogenase reductase Sdr
FR761_07960	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FR761_07980	COG2205	protein histidine kinase activity
FR761_07980	COG0784	Response regulator, receiver
FR761_08020	COG0765	amino acid transport
FR761_08030	COG1126	abc transporter atp-binding protein
FR761_08035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FR761_08040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FR761_08060	COG1280	lysine exporter protein (LysE YggA)
FR761_08065	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FR761_08075	COG1045	serine acetyltransferase
FR761_08085	COG1028	Short-chain dehydrogenase reductase Sdr
FR761_08090	COG0583	DNA-binding transcription factor activity
FR761_08095	COG0625	glutathione transferase activity
FR761_08100	COG0625	glutathione transferase activity
FR761_08105	COG0583	DNA-binding transcription factor activity
FR761_08115	COG1346	cytolysis
FR761_08145	COG2814	Major facilitator Superfamily
FR761_08155	COG0583	DNA-binding transcription factor activity
FR761_08165	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FR761_08170	COG3052	prosthetic group binding
FR761_08190	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FR761_08210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FR761_08220	COG1294	oxidase, subunit
FR761_08225	COG1271	oxidase subunit
FR761_08250	COG0477	Major facilitator Superfamily
FR761_08260	COG4521	taurine ABC transporter
FR761_08265	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FR761_08270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FR761_08275	COG2175	clavaminate synthase activity
FR761_08285	COG1953	Uracil, thiamine, allantoin
FR761_08305	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FR761_08320	COG0640	Transcriptional regulator
FR761_08325	COG0798	PFAM Bile acid sodium symporter
FR761_08330	COG0583	DNA-binding transcription factor activity
FR761_08345	COG3634	alkyl hydroperoxide reductase activity
FR761_08385	COG0436	Aminotransferase
FR761_08395	COG0386	Belongs to the glutathione peroxidase family
FR761_08435	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FR761_08460	COG0012	GTP binding
FR761_08465	COG2011	ABC-type metal ion transport system permease component
FR761_08470	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FR761_08480	COG1464	Belongs to the NlpA lipoprotein family
FR761_08510	COG0765	amino acid transport
FR761_08515	COG0765	amino acid transport
FR761_08520	COG1126	abc transporter atp-binding protein
FR761_08530	COG1522	sequence-specific DNA binding
FR761_08560	COG2826	transposase and inactivated derivatives, IS30 family
FR761_08585	COG2826	transposase and inactivated derivatives, IS30 family
FR761_08605	COG3328	transposase activity
FR761_08620	COG0697	spore germination
FR761_08650	COG3121	Chaperone
FR761_08655	COG3539	Fimbrial protein
FR761_08680	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FR761_08680	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FR761_08725	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FR761_08735	COG2353	YceI-like domain
FR761_08745	COG3698	Phosphodiester glycosidase
FR761_08760	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FR761_08775	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FR761_08775	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FR761_08775	COG0506	proline dehydrogenase activity
FR761_08785	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FR761_08790	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FR761_08810	COG1132	(ABC) transporter
FR761_08815	COG3122	Protein conserved in bacteria
FR761_08820	COG3619	membrane
FR761_08830	COG0640	Transcriptional regulator
FR761_08840	COG2850	peptidyl-arginine hydroxylation
FR761_08845	COG0424	maF-like protein
FR761_08865	COG0191	fructose-bisphosphate aldolase activity
FR761_08870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FR761_08885	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FR761_08895	COG1192	Involved in chromosome partitioning
FR761_08900	COG1475	DNA binding
FR761_08905	COG0811	peptide transport
FR761_08915	COG1132	(ABC) transporter
FR761_08920	COG1663	tetraacyldisaccharide 4'-kinase activity
FR761_08940	COG0084	hydrolase, TatD family'
FR761_08955	COG2165	general secretion pathway protein
FR761_08985	COG0590	tRNA wobble adenosine to inosine editing
FR761_09005	COG0776	regulation of translation
FR761_09035	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FR761_09040	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FR761_09095	COG0339	signal peptide processing
FR761_09100	COG0601	transmembrane transport
FR761_09105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FR761_09140	COG0702	epimerase
FR761_09145	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FR761_09165	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FR761_09195	COG0316	Belongs to the HesB IscA family
FR761_09200	COG0822	iron-sulfur transferase activity
FR761_09225	COG0776	regulation of translation
FR761_09230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FR761_09235	COG2207	Transcriptional regulator
FR761_09240	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FR761_09245	COG1960	acyl-CoA dehydrogenase activity
FR761_09250	COG1960	acyl-CoA dehydrogenase activity
FR761_09265	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FR761_09300	COG4264	IucA IucC family
FR761_09310	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FR761_09355	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FR761_09360	COG0406	alpha-ribazole phosphatase activity
FR761_09375	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FR761_09380	COG0730	response to heat
FR761_09405	COG4773	Receptor
FR761_09410	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FR761_09450	COG0842	Transport permease protein
FR761_09500	COG3293	Transposase
FR761_09525	COG2226	methyltransferase
FR761_09550	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FR761_09585	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FR761_09595	COG0133	tryptophan synthase activity
FR761_09610	COG3706	GGDEF domain
FR761_09635	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FR761_09640	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FR761_09645	COG0022	dehydrogenase e1 component
FR761_09650	COG0508	dehydrogenase complex catalyzes the overall conversion of
FR761_09655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FR761_09665	COG1063	alcohol dehydrogenase
FR761_09670	COG3781	membrane
FR761_09680	COG3453	Protein conserved in bacteria
FR761_09680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FR761_09690	COG0730	response to heat
FR761_09705	COG3708	Transcriptional regulator
FR761_09705	COG2207	Transcriptional regulator
FR761_09710	COG1733	regulation of RNA biosynthetic process
FR761_09715	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FR761_09740	COG4521	taurine ABC transporter
FR761_09775	COG0477	Major facilitator Superfamily
FR761_09785	COG1027	Aspartate ammonia-lyase
FR761_09790	COG2826	transposase and inactivated derivatives, IS30 family
FR761_09800	COG0583	DNA-binding transcription factor activity
FR761_09805	COG0583	DNA-binding transcription factor activity
FR761_09810	COG0183	Belongs to the thiolase family
FR761_09815	COG2031	fatty acid transporter
FR761_09830	COG0583	DNA-binding transcription factor activity
FR761_09855	COG1309	transcriptional regulator
FR761_09875	COG1028	Short-chain dehydrogenase reductase Sdr
FR761_09880	COG2207	Transcriptional regulator
FR761_09890	COG0412	Dienelactone hydrolase
FR761_09895	COG1028	Short-chain dehydrogenase reductase Sdr
FR761_09905	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FR761_09925	COG0543	2 iron, 2 sulfur cluster binding
FR761_09925	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FR761_09930	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FR761_09935	COG4638	Rieske (2fe-2S)
FR761_09945	COG0725	ABC transporter, periplasmic molybdate-binding protein
FR761_09950	COG4149	molybdate abc transporter
FR761_09955	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FR761_09960	COG1028	Short-chain dehydrogenase reductase Sdr
FR761_09965	COG1535	isochorismatase
FR761_09965	COG3433	isochorismatase activity
FR761_10030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FR761_10065	COG0747	negative chemotaxis
FR761_10070	COG0601	transmembrane transport
FR761_10075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FR761_10100	COG1132	(ABC) transporter
FR761_10105	COG1132	(ABC) transporter
FR761_10135	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FR761_10140	COG3657	addiction module killer protein
FR761_10170	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FR761_10185	COG1979	alcohol dehydrogenase
FR761_10195	COG1902	pentaerythritol trinitrate reductase activity
FR761_10205	COG1309	transcriptional regulator
FR761_10210	COG2130	NADP-dependent
FR761_10225	COG0582	viral genome integration into host DNA
FR761_10240	COG1733	regulation of RNA biosynthetic process
FR761_10245	COG0583	DNA-binding transcription factor activity
FR761_10260	COG0583	DNA-binding transcription factor activity
FR761_10275	COG0697	spore germination
FR761_10295	COG0071	Belongs to the small heat shock protein (HSP20) family
FR761_10300	COG0542	response to heat
FR761_10375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FR761_10390	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
FR761_10415	COG0745	RESPONSE REGULATOR receiver
FR761_10435	COG2207	Transcriptional regulator
FR761_10450	COG1028	Short-chain dehydrogenase reductase Sdr
FR761_10475	COG1309	transcriptional regulator
FR761_10500	COG0789	Transcriptional regulator
FR761_10515	COG0446	pyridine nucleotide-disulphide oxidoreductase
FR761_10515	COG1902	pentaerythritol trinitrate reductase activity
FR761_10530	COG1012	belongs to the aldehyde dehydrogenase family
FR761_10550	COG2186	Transcriptional regulator
FR761_10560	COG0583	DNA-binding transcription factor activity
FR761_10565	COG4948	Mandelate Racemase Muconate Lactonizing
FR761_10570	COG4829	muconolactone delta-isomerase
FR761_10580	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FR761_10585	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FR761_10590	COG0183	Belongs to the thiolase family
FR761_10595	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FR761_10600	COG1012	belongs to the aldehyde dehydrogenase family
FR761_10610	COG3733	amine oxidase
FR761_10620	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FR761_10630	COG1028	Short-chain dehydrogenase reductase Sdr
FR761_10640	COG4638	Rieske (2fe-2S)
FR761_10660	COG0154	amidase activity
FR761_10670	COG2814	Major facilitator Superfamily
FR761_10695	COG1960	acyl-CoA dehydrogenase activity
FR761_10700	COG0583	DNA-binding transcription factor activity
FR761_10705	COG1414	Transcriptional regulator
FR761_10720	COG2391	methyltransferase activity
FR761_10730	COG4993	Dehydrogenase
FR761_10735	COG3659	wide pore channel activity
FR761_10740	COG3420	alginic acid biosynthetic process
FR761_10745	COG0710	3-dehydroquinate dehydratase activity
FR761_10750	COG3485	protocatechuate 3,4-dioxygenase
FR761_10755	COG3485	protocatechuate 3,4-dioxygenase
FR761_10760	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FR761_10765	COG2271	Major facilitator Superfamily
FR761_10770	COG0596	Alpha beta hydrolase
FR761_10775	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FR761_10780	COG0183	Belongs to the thiolase family
FR761_10785	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FR761_10790	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FR761_10800	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FR761_10805	COG2323	membrane
FR761_10850	COG1902	pentaerythritol trinitrate reductase activity
FR761_10850	COG0446	pyridine nucleotide-disulphide oxidoreductase
FR761_10865	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FR761_10870	COG3293	Transposase
FR761_10880	COG0542	response to heat
FR761_10885	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FR761_10915	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FR761_10920	COG0569	domain protein
FR761_10925	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FR761_10940	COG4774	siderophore transport
FR761_10945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FR761_10975	COG1294	oxidase, subunit
FR761_10980	COG4890	Cyd operon protein YbgT
FR761_10995	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FR761_11005	COG0552	protein localization to endoplasmic reticulum
FR761_11035	COG0517	IMP dehydrogenase activity
FR761_11035	COG0516	GMP reductase activity
FR761_11040	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FR761_11045	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FR761_11055	COG0583	DNA-binding transcription factor activity
FR761_11060	COG0024	Methionine aminopeptidase
FR761_11090	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR761_11090	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FR761_11095	COG1105	Belongs to the carbohydrate kinase PfkB family
FR761_11100	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FR761_11100	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FR761_11100	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FR761_11130	COG1011	Hydrolase
FR761_11135	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FR761_11145	COG2137	regulation of response to DNA damage stimulus
FR761_11160	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FR761_11195	COG0575	Belongs to the CDS family
FR761_11200	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FR761_11220	COG3852	Histidine kinase
FR761_11225	COG2204	response regulator
FR761_11290	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FR761_11295	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FR761_11315	COG0697	spore germination
FR761_11320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FR761_11330	COG0303	'Molybdopterin
FR761_11335	COG0521	Mo-molybdopterin cofactor biosynthetic process
FR761_11335	COG0315	cyclic pyranopterin monophosphate synthase activity
FR761_11350	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FR761_11355	COG0243	molybdopterin cofactor binding
FR761_11365	COG0243	molybdopterin cofactor binding
FR761_11370	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FR761_11375	COG2146	nitrite reductase [NAD(P)H] activity
FR761_11375	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FR761_11385	COG0745	RESPONSE REGULATOR receiver
FR761_11390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FR761_11390	COG1116	anion transmembrane transporter activity
FR761_11405	COG0511	ligase activity, forming carbon-carbon bonds
FR761_11420	COG2814	Major facilitator Superfamily
FR761_11440	COG0069	glutamate synthase activity
FR761_11460	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FR761_11470	COG1454	alcohol dehydrogenase
FR761_11475	COG0824	Thioesterase
FR761_11485	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FR761_11515	COG0183	Belongs to the thiolase family
FR761_11525	COG0583	DNA-binding transcription factor activity
FR761_11540	COG1522	sequence-specific DNA binding
FR761_11545	COG3135	benzoate transporter
FR761_11575	COG0589	response to stress
FR761_11580	COG0488	(ABC) transporter
FR761_11600	COG4773	Receptor
FR761_11650	COG1605	Chorismate mutase
FR761_11670	COG0308	aminopeptidase N
FR761_11690	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FR761_11700	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FR761_11705	COG1454	alcohol dehydrogenase
FR761_11725	COG0531	amino acid
FR761_11730	COG4303	Ethanolamine ammonia lyase large subunit
FR761_11735	COG4302	ethanolamine ammonia-lyase activity
FR761_11740	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FR761_11740	COG0519	Catalyzes the synthesis of GMP from XMP
FR761_11765	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FR761_11780	COG0697	spore germination
FR761_11785	COG1923	regulation of RNA biosynthetic process
FR761_11795	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FR761_11800	COG0802	atpase or kinase
FR761_11820	COG1187	pseudouridine synthase activity
FR761_11835	COG0583	DNA-binding transcription factor activity
FR761_11850	COG2814	Major facilitator Superfamily
FR761_11855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FR761_11890	COG0729	surface antigen
FR761_11910	COG0174	glutamine synthetase
FR761_11915	COG0745	RESPONSE REGULATOR receiver
FR761_11920	COG2205	protein histidine kinase activity
FR761_11930	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FR761_11935	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FR761_11960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FR761_11965	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FR761_11970	COG1960	acyl-CoA dehydrogenase activity
FR761_11985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FR761_11990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FR761_12005	COG3328	transposase activity
FR761_12030	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FR761_12035	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FR761_12045	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FR761_12070	COG0305	Participates in initiation and elongation during chromosome replication
FR761_12075	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FR761_12085	COG1305	Transglutaminase-like
FR761_12095	COG2308	Evidence 4 Homologs of previously reported genes of
FR761_12125	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FR761_12130	COG0138	bifunctional purine biosynthesis protein purh
FR761_12135	COG0151	Belongs to the GarS family
FR761_12140	COG1464	Belongs to the NlpA lipoprotein family
FR761_12145	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FR761_12150	COG2011	ABC-type metal ion transport system permease component
FR761_12155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FR761_12165	COG1301	dicarboxylic acid transport
FR761_12195	COG1794	racemase activity, acting on amino acids and derivatives
FR761_12205	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FR761_12205	COG3008	intermembrane lipid transfer
FR761_12210	COG2995	paraquat-inducible protein a
FR761_12310	COG2186	Transcriptional regulator
FR761_12320	COG0786	glutamate:sodium symporter activity
FR761_12325	COG3243	poly(R)-hydroxyalkanoic acid synthase
FR761_12410	COG2815	serine threonine protein kinase
FR761_12410	COG0515	serine threonine protein kinase
FR761_12435	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FR761_12440	COG1610	YqeY-like protein
FR761_12445	COG4783	chaperone-mediated protein folding
FR761_12470	COG1286	toxin biosynthetic process
FR761_12500	COG0778	Nitroreductase
FR761_12510	COG0513	Belongs to the DEAD box helicase family
FR761_12530	COG2363	Small membrane protein
FR761_12560	COG4650	regulator
FR761_12565	COG1234	tRNA 3'-trailer cleavage
FR761_12570	COG2195	Cleaves the N-terminal amino acid of tripeptides
FR761_12580	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FR761_12590	COG2819	hydrolase of the alpha beta superfamily
FR761_12595	COG1960	acyl-CoA dehydrogenase activity
FR761_12600	COG1301	dicarboxylic acid transport
FR761_12615	COG3139	Protein of unknown function (DUF1315)
FR761_12620	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FR761_12625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FR761_12635	COG0494	nUDIX hydrolase
FR761_12645	COG0642	Histidine kinase
FR761_12650	COG0745	RESPONSE REGULATOR receiver
FR761_12670	COG1720	tRNA m6t6A37 methyltransferase activity
FR761_12685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FR761_12695	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FR761_12705	COG4598	ABC transporter
FR761_12710	COG4160	amino acid transport
FR761_12715	COG4215	(ABC) transporter
FR761_12730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR761_12740	COG1538	Outer membrane efflux protein
FR761_12775	COG1131	(ABC) transporter
FR761_12780	COG0842	Transport permease protein
FR761_12795	COG0772	Belongs to the SEDS family
FR761_12800	COG2951	lytic endotransglycosylase activity
FR761_12825	COG2207	Transcriptional regulator
FR761_12840	COG0052	Belongs to the universal ribosomal protein uS2 family
FR761_12845	COG0024	Methionine aminopeptidase
FR761_12860	COG2223	nitrite transmembrane transporter activity
FR761_12870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FR761_12875	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FR761_12880	COG1960	acyl-CoA dehydrogenase activity
FR761_12895	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FR761_12900	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FR761_12905	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FR761_12925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FR761_12930	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FR761_12935	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FR761_12970	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FR761_12995	COG3104	oligopeptide transport
FR761_13005	COG0512	Glutamine amidotransferase of anthranilate synthase
FR761_13010	COG0308	aminopeptidase N
FR761_13040	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FR761_13050	COG0302	gtp cyclohydrolase
FR761_13070	COG3739	integral membrane protein
FR761_13105	COG1132	(ABC) transporter
FR761_13120	COG1535	isochorismatase
FR761_13120	COG3433	isochorismatase activity
FR761_13125	COG1021	2,3-dihydroxybenzoate-AMP ligase
FR761_13130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FR761_13140	COG4774	siderophore transport
FR761_13145	COG4607	ABC-type enterochelin transport system periplasmic component
FR761_13150	COG4604	ABC transporter, ATP-binding protein
FR761_13155	COG4605	iron ion homeostasis
FR761_13160	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FR761_13165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FR761_13180	COG2964	Protein conserved in bacteria
FR761_13190	COG1741	Belongs to the pirin family
FR761_13320	COG0582	viral genome integration into host DNA
FR761_13330	COG2879	small protein
FR761_13335	COG1966	Carbon starvation protein
FR761_13380	COG1067	ATP-dependent peptidase activity
FR761_13385	COG0583	DNA-binding transcription factor activity
FR761_13410	COG1686	Belongs to the peptidase S11 family
FR761_13415	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FR761_13450	COG0616	signal peptide processing
FR761_13455	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FR761_13465	COG0573	inorganic phosphate transmembrane transporter activity
FR761_13470	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FR761_13475	COG1113	amino acid transport
FR761_13480	COG3961	Belongs to the TPP enzyme family
FR761_13485	COG1522	sequence-specific DNA binding
FR761_13495	COG0076	glutamate decarboxylase activity
FR761_13500	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FR761_13510	COG1309	transcriptional regulator
FR761_13525	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FR761_13560	COG0352	thiamine-phosphate diphosphorylase activity
FR761_13585	COG1203	CRISPR-associated helicase, Cas3
FR761_13615	COG0612	Peptidase, M16
FR761_13630	COG0583	DNA-binding transcription factor activity
FR761_13635	COG0477	Major facilitator Superfamily
FR761_13660	COG0582	viral genome integration into host DNA
FR761_13800	COG3566	protein conserved in bacteria
FR761_13815	COG3567	Phage-associated protein, HI1409 family
FR761_13820	COG5410	chromosome segregation
FR761_14005	COG1187	pseudouridine synthase activity
FR761_14020	COG1686	Belongs to the peptidase S11 family
FR761_14025	COG1252	NADH dehydrogenase
FR761_14035	COG0415	Belongs to the DNA photolyase family
FR761_14050	COG1215	transferase activity, transferring glycosyl groups
FR761_14080	COG2070	2-Nitropropane dioxygenase
FR761_14135	COG0556	nucleotide-excision repair
FR761_14185	COG4221	oxidoreductase activity
FR761_14195	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FR761_14200	COG1381	Involved in DNA repair and RecF pathway recombination
FR761_14210	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FR761_14225	COG0681	Belongs to the peptidase S26 family
FR761_14235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FR761_14245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FR761_14265	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FR761_14270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FR761_14275	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FR761_14285	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FR761_14290	COG4208	sulfate ABC transporter
FR761_14295	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FR761_14300	COG0583	DNA-binding transcription factor activity
FR761_14305	COG4625	pathogenesis
FR761_14320	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FR761_14335	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FR761_14340	COG3328	transposase activity
FR761_14350	COG1051	belongs to the nudix hydrolase family
FR761_14350	COG1056	cytidyltransferase-related domain
FR761_14355	COG1024	Enoyl-CoA hydratase
FR761_14360	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FR761_14365	COG2814	Major facilitator Superfamily
FR761_14370	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FR761_14370	COG0047	phosphoribosylformylglycinamidine synthase activity
FR761_14390	COG1473	amidohydrolase
FR761_14395	COG0824	Thioesterase
FR761_14415	COG0823	Involved in the tonB-independent uptake of proteins
FR761_14435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FR761_14475	COG0628	permease
FR761_14485	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FR761_14490	COG0596	Alpha beta hydrolase
FR761_14495	COG0616	signal peptide processing
FR761_14495	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FR761_14505	COG2333	competence protein COMEC
FR761_14505	COG0658	competence protein
FR761_14510	COG1136	(ABC) transporter
FR761_14515	COG4591	ABC-type transport system involved in lipoprotein release permease component
FR761_14545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR761_14565	COG0463	Glycosyl transferase, family 2
FR761_14595	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FR761_14600	COG1280	lysine exporter protein (LysE YggA)
FR761_14610	COG0019	diaminopimelate decarboxylase activity
FR761_14620	COG1113	amino acid transport
FR761_14635	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FR761_14645	COG3339	Conserved Protein
FR761_14650	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FR761_14655	COG0243	molybdopterin cofactor binding
FR761_14660	COG1929	Belongs to the glycerate kinase type-1 family
FR761_14670	COG0300	oxidoreductase activity
FR761_14675	COG0778	Nitroreductase
FR761_14710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FR761_14715	COG2826	transposase and inactivated derivatives, IS30 family
FR761_14730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FR761_14755	COG0741	lytic transglycosylase activity
FR761_14775	COG0584	glycerophosphoryl diester phosphodiesterase
FR761_14780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FR761_14790	COG0582	viral genome integration into host DNA
FR761_14795	COG1074	ATP-dependent DNA helicase activity
FR761_14815	COG1230	cation diffusion facilitator family transporter
FR761_14830	COG2814	Major facilitator Superfamily
FR761_14940	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FR761_14960	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FR761_14965	COG0477	Major facilitator Superfamily
FR761_15015	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FR761_15020	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FR761_15045	COG0505	Belongs to the CarA family
FR761_15060	COG1309	transcriptional regulator
FR761_15065	COG0251	oxidation-reduction process
FR761_15075	COG0589	response to stress
FR761_15090	COG2843	Capsule synthesis protein
FR761_15100	COG2826	transposase and inactivated derivatives, IS30 family
FR761_15105	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FR761_15130	COG2321	neutral zinc metallopeptidase
FR761_15135	COG2354	Protein conserved in bacteria
FR761_15155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FR761_15180	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FR761_15185	COG1053	succinate dehydrogenase
FR761_15190	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FR761_15195	COG2009	succinate dehydrogenase
FR761_15230	COG2921	Belongs to the UPF0250 family
FR761_15235	COG0321	lipoyl(octanoyl) transferase activity
FR761_15250	COG0531	amino acid
FR761_15260	COG1733	regulation of RNA biosynthetic process
FR761_15265	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FR761_15270	COG1648	precorrin-2 dehydrogenase activity
FR761_15270	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FR761_15285	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FR761_15315	COG0671	phosphoesterase, PA-phosphatase related
FR761_15320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR761_15330	COG1538	Outer membrane efflux protein
FR761_15335	COG0393	Putative heavy-metal-binding
FR761_15340	COG0393	Putative heavy-metal-binding
FR761_15350	COG1028	Short-chain dehydrogenase reductase Sdr
FR761_15360	COG0525	valine-tRNA ligase activity
FR761_15385	COG0583	DNA-binding transcription factor activity
FR761_15395	COG0004	ammonium transporteR
FR761_15405	COG0642	Histidine kinase
FR761_15410	COG0745	RESPONSE REGULATOR receiver
FR761_15415	COG2194	sulfuric ester hydrolase activity
FR761_15435	COG1752	Esterase of the alpha-beta hydrolase superfamily
FR761_15450	COG2315	Protein conserved in bacteria
FR761_15455	COG0142	geranyltranstransferase activity
FR761_15460	COG2828	Protein conserved in bacteria
FR761_15465	COG1113	amino acid transport
FR761_15475	COG0582	viral genome integration into host DNA
FR761_15520	COG2826	transposase and inactivated derivatives, IS30 family
FR761_15555	COG2207	Transcriptional regulator
FR761_15580	COG2249	NAD(P)H dehydrogenase (quinone) activity
FR761_15600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FR761_15610	COG1530	ribonuclease E activity
FR761_15615	COG0424	maF-like protein
FR761_15620	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FR761_15625	COG1792	Involved in formation and maintenance of cell shape
FR761_15630	COG1077	Cell shape determining protein MreB Mrl
FR761_15635	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FR761_15645	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FR761_15665	COG3590	peptidase
FR761_15670	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FR761_15675	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FR761_15680	COG1752	Esterase of the alpha-beta hydrolase superfamily
FR761_15685	COG1115	amino acid carrier protein
FR761_15705	COG2814	Major facilitator Superfamily
FR761_15710	COG1289	transmembrane transporter activity
FR761_15760	COG1376	ErfK ybiS ycfS ynhG family protein
FR761_15765	COG2832	Protein of unknown function (DUF454)
FR761_15775	COG5510	response to toxic substance
FR761_15795	COG0840	transmembrane signaling receptor activity
FR761_15835	COG3422	double-strand break repair
FR761_15840	COG2824	Alkylphosphonate utilization operon protein PhnA
FR761_15845	COG3189	MarR family transcriptional regulator
FR761_15855	COG0354	folic acid binding
FR761_15860	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FR761_15890	COG1902	pentaerythritol trinitrate reductase activity
FR761_15895	COG4772	TonB-dependent receptor
FR761_15900	COG2094	Belongs to the DNA glycosylase MPG family
FR761_15930	COG2233	PERMEase
FR761_15940	COG0833	amino acid
FR761_15945	COG1690	Belongs to the RtcB family
FR761_15950	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FR761_15950	COG2885	chlorophyll binding
FR761_15960	COG0183	Belongs to the thiolase family
FR761_15980	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FR761_16000	COG2207	Transcriptional regulator
FR761_16005	COG0183	Belongs to the thiolase family
FR761_16035	COG1272	protein, Hemolysin III
FR761_16040	COG0477	Major facilitator Superfamily
FR761_16055	COG0450	alkyl hydroperoxide reductase
FR761_16075	COG0285	dihydrofolate synthase activity
FR761_16110	COG0133	tryptophan synthase activity
FR761_16125	COG2096	Adenosyltransferase
FR761_16130	COG0584	glycerophosphoryl diester phosphodiesterase
FR761_16145	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FR761_16150	COG0745	RESPONSE REGULATOR receiver
FR761_16155	COG2205	protein histidine kinase activity
FR761_16165	COG1960	acyl-CoA dehydrogenase activity
FR761_16170	COG1960	acyl-CoA dehydrogenase activity
FR761_16220	COG1442	glycosyl transferase family 8
FR761_16230	COG2826	transposase and inactivated derivatives, IS30 family
FR761_16265	COG0438	transferase activity, transferring glycosyl groups
FR761_16275	COG0438	transferase activity, transferring glycosyl groups
FR761_16280	COG0726	polysaccharide deacetylase
FR761_16295	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FR761_16300	COG2205	protein histidine kinase activity
FR761_16310	COG3646	Phage regulatory protein
FR761_16340	COG4695	Portal protein
FR761_16480	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FR761_16490	COG3646	Phage regulatory protein
FR761_16530	COG0629	single-stranded DNA binding
FR761_16595	COG1862	Preprotein translocase
FR761_16605	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FR761_16610	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FR761_16620	COG3781	membrane
FR761_16625	COG0613	PHP domain protein
FR761_16635	COG2350	Protein conserved in bacteria
FR761_16665	COG1607	acyl-coa hydrolase
FR761_16680	COG3453	Protein conserved in bacteria
FR761_16680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FR761_16690	COG2826	transposase and inactivated derivatives, IS30 family
FR761_16730	COG2199	diguanylate cyclase activity
FR761_16740	COG1408	metallophosphoesterase
FR761_16745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FR761_16755	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FR761_16775	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FR761_16780	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FR761_16785	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FR761_16795	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FR761_16805	COG2969	positive regulation of protein catabolic process
FR761_16825	COG1960	acyl-CoA dehydrogenase activity
FR761_16830	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FR761_16845	COG1309	transcriptional regulator
FR761_16850	COG1960	acyl-CoA dehydrogenase activity
FR761_16895	COG1183	phosphatidylcholine synthase activity
FR761_16900	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FR761_16930	COG0739	heme binding
FR761_16930	COG0741	lytic transglycosylase activity
FR761_16930	COG1196	nuclear chromosome segregation
FR761_16940	COG1702	phosphate starvation-inducible protein PhoH
FR761_16975	COG1295	ribonuclease BN
FR761_16980	COG0697	spore germination
FR761_16985	COG2169	Transcriptional regulator
FR761_16990	COG0179	Fumarylacetoacetate (FAA) hydrolase
FR761_17035	COG0557	exoribonuclease II activity
FR761_17040	COG0339	signal peptide processing
FR761_17045	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FR761_17075	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FR761_17130	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FR761_17140	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FR761_17260	COG0626	cystathionine gamma-synthase activity
FR761_17265	COG0433	COG0433 Predicted ATPase
FR761_17275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FR761_17275	COG1017	nitric oxide dioxygenase activity
FR761_17280	COG1959	2 iron, 2 sulfur cluster binding
FR761_17295	COG1301	dicarboxylic acid transport
FR761_17300	COG1946	Acyl-CoA thioesterase
FR761_17320	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FR761_17325	COG1040	competence protein
FR761_17330	COG0494	nUDIX hydrolase
FR761_17340	COG0598	Magnesium transport protein CorA
FR761_17350	COG2854	intermembrane phospholipid transfer
FR761_17360	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FR761_17365	COG1127	ABC transporter
FR761_17375	COG0513	Belongs to the DEAD box helicase family
FR761_17395	COG0408	coproporphyrinogen oxidase activity
FR761_17410	COG1960	acyl-CoA dehydrogenase activity
FR761_17420	COG1983	PspC domain protein
FR761_17425	COG0517	IMP dehydrogenase activity
FR761_17470	COG0583	DNA-binding transcription factor activity
FR761_17510	COG1012	belongs to the aldehyde dehydrogenase family
FR761_17520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FR761_17525	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FR761_17530	COG0833	amino acid
FR761_17560	COG1192	Involved in chromosome partitioning
FR761_17565	COG0628	permease
FR761_17575	COG1289	transmembrane transporter activity
FR761_17590	COG2249	NAD(P)H dehydrogenase (quinone) activity
FR761_17595	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FR761_17605	COG0277	FAD linked oxidase domain protein
FR761_17610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FR761_17635	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FR761_17640	COG5380	lipid catabolic process
FR761_17660	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FR761_17710	COG0194	GDP metabolic process
FR761_17725	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FR761_17745	COG3307	-O-antigen
FR761_17755	COG4969	Belongs to the N-Me-Phe pilin family
FR761_17765	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FR761_17770	COG1704	LemA family
FR761_17780	COG0493	'glutamate synthase
FR761_17785	COG0070	glutamate synthase
FR761_17785	COG0069	glutamate synthase activity
FR761_17785	COG0067	glutamate synthase
FR761_17835	COG2226	methyltransferase
FR761_17850	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FR761_17855	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FR761_17900	COG0833	amino acid
FR761_17920	COG0582	viral genome integration into host DNA
FR761_17930	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FR761_17940	COG2826	transposase and inactivated derivatives, IS30 family
FR761_18050	COG3293	Transposase
FR761_18085	COG0488	(ABC) transporter
FR761_18095	COG4221	oxidoreductase activity
FR761_18100	COG0659	secondary active sulfate transmembrane transporter activity
FR761_18110	COG0745	RESPONSE REGULATOR receiver
FR761_18125	COG0427	acetyl-CoA hydrolase
FR761_18155	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FR761_18195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FR761_18250	COG0582	viral genome integration into host DNA
FR761_18340	COG0667	Aldo Keto reductase
FR761_18360	COG0583	DNA-binding transcription factor activity
FR761_18365	COG2814	Major facilitator Superfamily
FR761_18395	COG1335	isochorismatase
FR761_18405	COG1012	belongs to the aldehyde dehydrogenase family
FR761_18410	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FR761_18420	COG1113	amino acid transport
FR761_18430	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FR761_18445	COG2814	Major facilitator Superfamily
FR761_18455	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FR761_18455	COG0352	thiamine-phosphate diphosphorylase activity
FR761_18455	COG0351	phosphomethylpyrimidine kinase
FR761_18475	COG1309	transcriptional regulator
FR761_18480	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FR761_18485	COG3706	GGDEF domain
FR761_18495	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FR761_18505	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FR761_18510	COG3162	membrane
FR761_18515	COG2205	protein histidine kinase activity
FR761_18515	COG2198	Histidine kinase
FR761_18515	COG0784	Response regulator, receiver
FR761_18540	COG1522	sequence-specific DNA binding
FR761_18545	COG1335	isochorismatase
FR761_18550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FR761_18560	COG3316	Transposase and inactivated derivatives
FR761_18570	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FR761_18580	COG3657	addiction module killer protein
FR761_18585	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FR761_18595	COG2801	Transposase and inactivated derivatives
FR761_18605	COG0659	secondary active sulfate transmembrane transporter activity
FR761_18640	COG2801	Transposase and inactivated derivatives
FR761_18660	COG3657	addiction module killer protein
FR761_18665	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FR761_18675	COG3173	Aminoglycoside phosphotransferase
FR761_18685	COG2801	Transposase and inactivated derivatives
FR761_18715	COG0745	RESPONSE REGULATOR receiver
FR761_18725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FR761_18730	COG1538	Outer membrane efflux protein
FR761_18745	COG3316	Transposase and inactivated derivatives
FR761_18790	COG3971	2-oxopent-4-enoate hydratase activity
FR761_18795	COG4569	acetaldehyde dehydrogenase (acetylating) activity
FR761_18800	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FR761_18805	COG0179	Fumarylacetoacetate (FAA) hydrolase
FR761_18865	COG1660	Displays ATPase and GTPase activities
FR761_18925	COG4977	sequence-specific DNA binding
FR761_18935	COG0583	DNA-binding transcription factor activity
FR761_18945	COG4941	Belongs to the sigma-70 factor family
FR761_18950	COG3795	YCII-related domain
FR761_18990	COG4106	trans-aconitate 2-methyltransferase activity
FR761_18995	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FR761_19005	COG1131	(ABC) transporter
FR761_19045	COG0860	N-Acetylmuramoyl-L-alanine amidase
FR761_19155	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FR761_19200	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FR761_19210	COG1525	nuclease
FR761_19265	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FR761_19370	COG2197	response regulator
FR761_19380	COG0154	amidase activity
FR761_19385	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FR761_19505	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FR761_19585	COG4372	Transposase
FR761_19660	COG3316	Transposase and inactivated derivatives
FR761_19720	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FR761_19750	COG3316	Transposase and inactivated derivatives
FR761_19760	COG3316	Transposase and inactivated derivatives
FR761_19895	COG1475	DNA binding
FR761_19900	COG1192	Involved in chromosome partitioning
FR761_20130	COG4783	chaperone-mediated protein folding
FR761_20210	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FR761_20240	COG0582	viral genome integration into host DNA
FR761_20255	COG1373	ATPase (AAA superfamily
FR761_20260	COG4680	protein conserved in bacteria
FR761_20280	COG3316	Transposase and inactivated derivatives
FR761_20305	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FR761_20310	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FR761_20335	COG0697	spore germination
FR761_20355	COG0804	urea catabolic process
FR761_20365	COG0831	urea catabolic process
FR761_20370	COG0829	nickel cation binding
FR761_20385	COG0830	nickel cation binding
FR761_20405	COG1475	DNA binding
FR761_20410	COG1192	Involved in chromosome partitioning
FR761_20470	COG0583	DNA-binding transcription factor activity
FR761_20595	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
FR761_20690	COG2076	Multidrug Resistance protein
FR761_20765	COG2337	Toxic component of a toxin-antitoxin (TA) module
FR761_20770	COG2336	PFAM SpoVT AbrB