locus-tag	class	description
OPM65_00010	COG0592	DNA-directed DNA polymerase activity
OPM65_00020	COG0187	DNA topoisomerase II activity
OPM65_00030	COG0586	Pfam SNARE associated Golgi protein
OPM65_00035	COG0488	(ABC) transporter
OPM65_00060	COG0596	Alpha beta hydrolase
OPM65_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OPM65_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OPM65_00110	COG1047	Peptidyl-prolyl cis-trans
OPM65_00120	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OPM65_00125	COG0196	riboflavin kinase activity
OPM65_00135	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OPM65_00140	COG1309	transcriptional regulator
OPM65_00145	COG1116	anion transmembrane transporter activity
OPM65_00150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OPM65_00155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OPM65_00160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OPM65_00165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OPM65_00185	COG1028	Short-chain dehydrogenase reductase Sdr
OPM65_00190	COG0546	phosphoglycolate phosphatase activity
OPM65_00250	COG3023	N-Acetylmuramoyl-L-alanine amidase
OPM65_00255	COG0728	peptidoglycan biosynthetic process
OPM65_00280	COG1596	polysaccharide export
OPM65_00285	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OPM65_00295	COG1215	transferase activity, transferring glycosyl groups
OPM65_00300	COG0438	transferase activity, transferring glycosyl groups
OPM65_00320	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OPM65_00325	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OPM65_00340	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OPM65_00350	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OPM65_00360	COG2186	Transcriptional regulator
OPM65_00370	COG0277	FAD linked oxidase domain protein
OPM65_00375	COG1448	Aminotransferase
OPM65_00385	COG1802	Transcriptional regulator
OPM65_00400	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OPM65_00465	COG0564	pseudouridine synthase activity
OPM65_00505	COG0251	oxidation-reduction process
OPM65_00515	COG1113	amino acid transport
OPM65_00520	COG1113	amino acid transport
OPM65_00540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OPM65_00545	COG1960	acyl-CoA dehydrogenase activity
OPM65_00550	COG1024	Enoyl-CoA hydratase
OPM65_00555	COG1024	Enoyl-CoA hydratase
OPM65_00560	COG0477	Major facilitator Superfamily
OPM65_00565	COG3916	Acyl-homoserine-lactone synthase
OPM65_00575	COG2197	response regulator
OPM65_00585	COG1960	acyl-CoA dehydrogenase activity
OPM65_00590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OPM65_00590	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OPM65_00590	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
OPM65_00590	COG3321	synthase
OPM65_00610	COG2267	carboxylic ester hydrolase activity
OPM65_00630	COG0271	Belongs to the BolA IbaG family
OPM65_00640	COG1192	Involved in chromosome partitioning
OPM65_00655	COG0586	Pfam SNARE associated Golgi protein
OPM65_00660	COG2259	Doxx family
OPM65_00665	COG4399	Belongs to the UPF0754 family
OPM65_00670	COG0519	Catalyzes the synthesis of GMP from XMP
OPM65_00670	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OPM65_00715	COG0281	malic enzyme
OPM65_00725	COG2837	iron assimilation
OPM65_00730	COG1280	lysine exporter protein (LysE YggA)
OPM65_00735	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OPM65_00740	COG1121	(ABC) transporter
OPM65_00805	COG0386	Belongs to the glutathione peroxidase family
OPM65_00820	COG1309	transcriptional regulator
OPM65_00825	COG0697	spore germination
OPM65_00835	COG0758	DNA mediated transformation
OPM65_00905	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OPM65_00915	COG0655	NAD(P)H dehydrogenase (quinone) activity
OPM65_00955	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OPM65_00975	COG1253	flavin adenine dinucleotide binding
OPM65_00985	COG2860	membrane
OPM65_00990	COG0477	Major facilitator Superfamily
OPM65_01000	COG0318	PFAM AMP-dependent synthetase and ligase
OPM65_01015	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OPM65_01035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OPM65_01045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OPM65_01090	COG0589	response to stress
OPM65_01095	COG0659	secondary active sulfate transmembrane transporter activity
OPM65_01115	COG1061	Type III restriction enzyme res subunit
OPM65_01120	COG1002	Type II restriction enzyme, methylase subunits
OPM65_01185	COG0347	Belongs to the P(II) protein family
OPM65_01190	COG0004	ammonium transporteR
OPM65_01200	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OPM65_01200	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OPM65_01240	COG0795	lipopolysaccharide-transporting ATPase activity
OPM65_01245	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OPM65_01250	COG0793	Belongs to the peptidase S41A family
OPM65_01265	COG2197	response regulator
OPM65_01275	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OPM65_01285	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OPM65_01290	COG4974	Belongs to the 'phage' integrase family
OPM65_01315	COG0772	Belongs to the SEDS family
OPM65_01320	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OPM65_01325	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OPM65_01330	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OPM65_01355	COG0697	spore germination
OPM65_01360	COG1538	Outer membrane efflux protein
OPM65_01380	COG3275	phosphorelay sensor kinase activity
OPM65_01390	COG0181	hydroxymethylbilane synthase activity
OPM65_01435	COG1716	ATPase activity
OPM65_01440	COG0546	phosphoglycolate phosphatase activity
OPM65_01535	COG0596	Alpha beta hydrolase
OPM65_01540	COG2056	Na+-H+ antiporter family
OPM65_01555	COG0326	Molecular chaperone. Has ATPase activity
OPM65_01570	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OPM65_01635	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OPM65_01640	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OPM65_01640	COG2169	Transcriptional regulator
OPM65_01670	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OPM65_01680	COG0497	DNA recombination
OPM65_01695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OPM65_01705	COG0237	dephospho-CoA kinase activity
OPM65_01755	COG0195	Participates in both transcription termination and antitermination
OPM65_01770	COG1320	monovalent cation:proton antiporter activity
OPM65_01775	COG2212	antiporter activity
OPM65_01780	COG1863	multisubunit Na H antiporter MnhE subunit
OPM65_01785	COG0651	ATP synthesis coupled electron transport
OPM65_01790	COG1006	Multisubunit Na H antiporter MnhC subunit
OPM65_01795	COG2111	Na H antiporter
OPM65_01795	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OPM65_01810	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OPM65_01815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OPM65_01830	COG2226	methyltransferase
OPM65_01850	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
OPM65_01855	COG1074	ATP-dependent DNA helicase activity
OPM65_01860	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OPM65_01865	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OPM65_01880	COG0598	Magnesium transport protein CorA
OPM65_01885	COG0789	Transcriptional regulator
OPM65_01890	COG0484	heat shock protein binding
OPM65_01900	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OPM65_01905	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OPM65_01905	COG0475	glutathione-regulated potassium exporter activity
OPM65_01910	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OPM65_01935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OPM65_01945	COG4535	Mg2 and Co2 transporter CorC
OPM65_01950	COG0425	Belongs to the sulfur carrier protein TusA family
OPM65_01955	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
OPM65_01955	COG0644	oxidoreductase
OPM65_01965	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OPM65_01980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OPM65_01985	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
OPM65_02025	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OPM65_02040	COG0534	Mate efflux family protein
OPM65_02050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OPM65_02055	COG4221	oxidoreductase activity
OPM65_02060	COG0583	DNA-binding transcription factor activity
OPM65_02075	COG0318	PFAM AMP-dependent synthetase and ligase
OPM65_02080	COG1530	ribonuclease E activity
OPM65_02090	COG0546	phosphoglycolate phosphatase activity
OPM65_02095	COG2378	regulation of single-species biofilm formation
OPM65_02100	COG0625	glutathione transferase activity
OPM65_02110	COG0583	DNA-binding transcription factor activity
OPM65_02175	COG0473	3-isopropylmalate dehydrogenase activity
OPM65_02230	COG1301	dicarboxylic acid transport
OPM65_02240	COG1560	Kdo2-lipid A biosynthetic process
OPM65_02245	COG1280	lysine exporter protein (LysE YggA)
OPM65_02250	COG0488	(ABC) transporter
OPM65_02255	COG2900	Belongs to the SlyX family
OPM65_02265	COG1733	regulation of RNA biosynthetic process
OPM65_02290	COG0210	DNA helicase
OPM65_02295	COG0724	RNA recognition motif
OPM65_02315	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OPM65_02315	COG4651	solute:proton antiporter activity
OPM65_02340	COG0788	formyltetrahydrofolate deformylase activity
OPM65_02440	COG2813	Specifically methylates the guanine in position
OPM65_02440	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OPM65_02450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OPM65_02470	COG0740	serine-type endopeptidase activity
OPM65_02490	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
OPM65_02490	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
OPM65_02495	COG0280	phosphate acetyltransferase
OPM65_02495	COG0857	belongs to the CobB CobQ family
OPM65_02500	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OPM65_02510	COG0800	Aldolase
OPM65_02520	COG3265	gluconokinase activity
OPM65_02525	COG1012	belongs to the aldehyde dehydrogenase family
OPM65_02535	COG2267	carboxylic ester hydrolase activity
OPM65_02550	COG0793	Belongs to the peptidase S41A family
OPM65_02585	COG1426	Protein conserved in bacteria
OPM65_02630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OPM65_02640	COG0318	PFAM AMP-dependent synthetase and ligase
OPM65_02655	COG2986	histidine ammonia-lyase
OPM65_02695	COG1028	Short-chain dehydrogenase reductase Sdr
OPM65_02700	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OPM65_02720	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OPM65_02730	COG1162	GTPase activity
OPM65_02735	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OPM65_02750	COG1538	Outer membrane efflux protein
OPM65_02755	COG1136	(ABC) transporter
OPM65_02755	COG0577	efflux transmembrane transporter activity
OPM65_02760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OPM65_02785	COG0028	Belongs to the TPP enzyme family
OPM65_02790	COG0440	acetolactate synthase activity
OPM65_02820	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OPM65_02835	COG0084	hydrolase, TatD family'
OPM65_02850	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OPM65_02860	COG0583	DNA-binding transcription factor activity
OPM65_02870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OPM65_02875	COG2814	Major facilitator Superfamily
OPM65_02885	COG0697	spore germination
OPM65_02915	COG3622	Belongs to the hyi family
OPM65_02920	COG2084	Dehydrogenase
OPM65_02925	COG1024	Enoyl-CoA hydratase
OPM65_02930	COG0784	Response regulator, receiver
OPM65_02930	COG2205	protein histidine kinase activity
OPM65_02930	COG5002	protein histidine kinase activity
OPM65_02950	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OPM65_02960	COG3956	TIGRFAM MazG family protein
OPM65_02965	COG1555	photosystem II stabilization
OPM65_02970	COG0617	tRNA 3'-terminal CCA addition
OPM65_02975	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OPM65_02995	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OPM65_03000	COG3028	Belongs to the UPF0307 family
OPM65_03005	COG0318	PFAM AMP-dependent synthetase and ligase
OPM65_03020	COG0625	glutathione transferase activity
OPM65_03025	COG1238	metal cluster binding
OPM65_03070	COG0072	phenylalanine-tRNA ligase activity
OPM65_03100	COG0248	Ppx GppA phosphatase
OPM65_03110	COG0037	tRNA processing
OPM65_03150	COG1764	response to oxidative stress
OPM65_03155	COG1846	Transcriptional regulator
OPM65_03165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OPM65_03225	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OPM65_03230	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OPM65_03235	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OPM65_03245	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OPM65_03295	COG1214	PFAM Peptidase M22, glycoprotease
OPM65_03320	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OPM65_03325	COG0561	phosphatase activity
OPM65_03335	COG2132	Multicopper oxidase
OPM65_03340	COG3667	copper resistance
OPM65_03355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OPM65_03360	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OPM65_03365	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OPM65_03395	COG1063	alcohol dehydrogenase
OPM65_03400	COG0583	DNA-binding transcription factor activity
OPM65_03405	COG1960	acyl-CoA dehydrogenase activity
OPM65_03410	COG2814	Major facilitator Superfamily
OPM65_03415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OPM65_03425	COG1053	succinate dehydrogenase
OPM65_03430	COG0583	DNA-binding transcription factor activity
OPM65_03445	COG0583	DNA-binding transcription factor activity
OPM65_03475	COG0583	DNA-binding transcription factor activity
OPM65_03490	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OPM65_03515	COG0384	phenazine biosynthesis protein PhzF
OPM65_03540	COG4993	Dehydrogenase
OPM65_03610	COG2205	protein histidine kinase activity
OPM65_03620	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OPM65_03640	COG0745	RESPONSE REGULATOR receiver
OPM65_03680	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OPM65_03710	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OPM65_03715	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OPM65_03735	COG0583	DNA-binding transcription factor activity
OPM65_03755	COG0668	transmembrane transport
OPM65_03765	COG2081	HI0933 family
OPM65_03770	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OPM65_03800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OPM65_03800	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OPM65_03810	COG0489	protein tyrosine kinase activity
OPM65_03860	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OPM65_03870	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OPM65_03885	COG0730	response to heat
OPM65_03895	COG1196	nuclear chromosome segregation
OPM65_03915	COG2223	nitrite transmembrane transporter activity
OPM65_03920	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
OPM65_03925	COG1877	trehalose-phosphatase activity
OPM65_03930	COG0596	Alpha beta hydrolase
OPM65_03930	COG2226	methyltransferase
OPM65_03930	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OPM65_03945	COG4106	trans-aconitate 2-methyltransferase activity
OPM65_03960	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OPM65_03965	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OPM65_03970	COG0009	L-threonylcarbamoyladenylate synthase
OPM65_03975	COG3101	peptidyl-lysine hydroxylation
OPM65_03980	COG1399	metal-binding, possibly nucleic acid-binding protein
OPM65_04005	COG1652	LysM domain
OPM65_04010	COG0352	thiamine-phosphate diphosphorylase activity
OPM65_04010	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OPM65_04010	COG0351	phosphomethylpyrimidine kinase
OPM65_04020	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OPM65_04050	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OPM65_04080	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
OPM65_04095	COG0358	DNA primase activity
OPM65_04105	COG0564	pseudouridine synthase activity
OPM65_04130	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OPM65_04150	COG0583	DNA-binding transcription factor activity
OPM65_04155	COG0473	3-isopropylmalate dehydrogenase activity
OPM65_04165	COG0657	acetylesterase activity
OPM65_04175	COG1012	belongs to the aldehyde dehydrogenase family
OPM65_04195	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OPM65_04195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OPM65_04210	COG1981	membrane
OPM65_04255	COG0456	acetyltransferase
OPM65_04265	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OPM65_04270	COG0492	ferredoxin-NADP+ reductase activity
OPM65_04275	COG1674	ftsk spoiiie
OPM65_04275	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OPM65_04280	COG1280	lysine exporter protein (LysE YggA)
OPM65_04300	COG2894	cell division
OPM65_04315	COG0204	Acyl-transferase
OPM65_04320	COG2885	chlorophyll binding
OPM65_04325	COG0210	DNA helicase
OPM65_04335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OPM65_04350	COG0121	glutamine amidotransferase
OPM65_04370	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OPM65_04375	COG0735	belongs to the Fur family
OPM65_04400	COG0420	3'-5' exonuclease activity
OPM65_04420	COG1090	epimerase
OPM65_04435	COG2050	protein possibly involved in aromatic compounds catabolism
OPM65_04445	COG2814	Major facilitator Superfamily
OPM65_04450	COG0405	Gamma-glutamyltransferase
OPM65_04605	COG2026	Addiction module toxin, RelE StbE family
OPM65_04650	COG0592	DNA-directed DNA polymerase activity
OPM65_04735	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OPM65_04790	COG0477	Major facilitator Superfamily
OPM65_04795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OPM65_04820	COG0531	amino acid
OPM65_04825	COG2040	homocysteine
OPM65_04850	COG1309	transcriptional regulator
OPM65_04855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OPM65_04860	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OPM65_04870	COG1607	acyl-coa hydrolase
OPM65_04880	COG0523	cobalamin synthesis protein
OPM65_04890	COG4681	YaeQ
OPM65_04900	COG0726	polysaccharide deacetylase
OPM65_04900	COG1649	PFAM Uncharacterised BCR, COG1649
OPM65_04905	COG1215	transferase activity, transferring glycosyl groups
OPM65_04915	COG1024	Enoyl-CoA hydratase
OPM65_04930	COG1414	Transcriptional regulator
OPM65_04950	COG1028	Short-chain dehydrogenase reductase Sdr
OPM65_04960	COG0446	pyridine nucleotide-disulphide oxidoreductase
OPM65_04965	COG2271	Major facilitator Superfamily
OPM65_04975	COG2267	carboxylic ester hydrolase activity
OPM65_04980	COG1028	Short-chain dehydrogenase reductase Sdr
OPM65_04995	COG0028	Belongs to the TPP enzyme family
OPM65_05005	COG0477	Major facilitator Superfamily
OPM65_05010	COG0242	peptide deformylase activity
OPM65_05015	COG2066	Belongs to the glutaminase family
OPM65_05020	COG2207	Transcriptional regulator
OPM65_05025	COG2223	nitrite transmembrane transporter activity
OPM65_05040	COG0583	DNA-binding transcription factor activity
OPM65_05045	COG1028	Short-chain dehydrogenase reductase Sdr
OPM65_05050	COG2271	Major facilitator Superfamily
OPM65_05055	COG3959	Transketolase, thiamine diphosphate binding domain
OPM65_05060	COG3958	Transketolase
OPM65_05070	COG0306	phosphate transporter
OPM65_05090	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OPM65_05135	COG4181	ATPase activity
OPM65_05140	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
OPM65_05165	COG0583	DNA-binding transcription factor activity
OPM65_05175	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OPM65_05180	COG1773	rubredoxin
OPM65_05230	COG2851	Citrate transporter
OPM65_05235	COG1253	flavin adenine dinucleotide binding
OPM65_05275	COG0804	urea catabolic process
OPM65_05285	COG0830	nickel cation binding
OPM65_05300	COG0742	ribosomal rna small subunit methyltransferase
OPM65_05305	COG0768	penicillin binding
OPM65_05330	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OPM65_05335	COG2878	Part of a membrane complex involved in electron transport
OPM65_05340	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OPM65_05350	COG3384	dioxygenase
OPM65_05635	COG0739	heme binding
OPM65_05680	COG2194	sulfuric ester hydrolase activity
OPM65_05720	COG0006	proline dipeptidase activity
OPM65_05725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OPM65_05730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OPM65_05750	COG1279	arginine transmembrane transporter activity
OPM65_05755	COG0583	DNA-binding transcription factor activity
OPM65_05830	COG0488	(ABC) transporter
OPM65_05835	COG3173	Aminoglycoside phosphotransferase
OPM65_05845	COG2433	Pfam Transposase IS66
OPM65_05885	COG1301	dicarboxylic acid transport
OPM65_05895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OPM65_05900	COG2011	ABC-type metal ion transport system permease component
OPM65_05905	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OPM65_05910	COG1464	Belongs to the NlpA lipoprotein family
OPM65_05915	COG0151	Belongs to the GarS family
OPM65_05920	COG0138	bifunctional purine biosynthesis protein purh
OPM65_05925	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
OPM65_05955	COG2308	Evidence 4 Homologs of previously reported genes of
OPM65_05965	COG1305	Transglutaminase-like
OPM65_05975	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OPM65_05980	COG0305	Participates in initiation and elongation during chromosome replication
OPM65_06005	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OPM65_06015	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OPM65_06020	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OPM65_06045	COG0726	polysaccharide deacetylase
OPM65_06045	COG1649	PFAM Uncharacterised BCR, COG1649
OPM65_06050	COG1215	transferase activity, transferring glycosyl groups
OPM65_06055	COG3658	cytochrome
OPM65_06065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OPM65_06080	COG0583	DNA-binding transcription factor activity
OPM65_06100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OPM65_06105	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OPM65_06120	COG1960	acyl-CoA dehydrogenase activity
OPM65_06125	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OPM65_06130	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OPM65_06155	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
OPM65_06160	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OPM65_06170	COG2205	protein histidine kinase activity
OPM65_06175	COG0745	RESPONSE REGULATOR receiver
OPM65_06180	COG0174	glutamine synthetase
OPM65_06200	COG0729	surface antigen
OPM65_06225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OPM65_06230	COG2814	Major facilitator Superfamily
OPM65_06245	COG0583	DNA-binding transcription factor activity
OPM65_06260	COG1187	pseudouridine synthase activity
OPM65_06280	COG0802	atpase or kinase
OPM65_06285	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OPM65_06295	COG1923	regulation of RNA biosynthetic process
OPM65_06300	COG0697	spore germination
OPM65_06315	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OPM65_06325	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OPM65_06330	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OPM65_06330	COG0519	Catalyzes the synthesis of GMP from XMP
OPM65_06335	COG4302	ethanolamine ammonia-lyase activity
OPM65_06340	COG4303	Ethanolamine ammonia lyase large subunit
OPM65_06345	COG0531	amino acid
OPM65_06365	COG1454	alcohol dehydrogenase
OPM65_06370	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OPM65_06380	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
OPM65_06400	COG0308	aminopeptidase N
OPM65_06410	COG4221	oxidoreductase activity
OPM65_06420	COG1605	Chorismate mutase
OPM65_06440	COG1309	transcriptional regulator
OPM65_06450	COG0668	transmembrane transport
OPM65_06485	COG4773	Receptor
OPM65_06505	COG0488	(ABC) transporter
OPM65_06510	COG0589	response to stress
OPM65_06535	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OPM65_06545	COG3135	benzoate transporter
OPM65_06550	COG1522	sequence-specific DNA binding
OPM65_06560	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OPM65_06565	COG0583	DNA-binding transcription factor activity
OPM65_06575	COG0183	Belongs to the thiolase family
OPM65_06585	COG2030	dehydratase
OPM65_06590	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OPM65_06605	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OPM65_06615	COG0824	Thioesterase
OPM65_06620	COG1454	alcohol dehydrogenase
OPM65_06630	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OPM65_06650	COG0069	glutamate synthase activity
OPM65_06670	COG2814	Major facilitator Superfamily
OPM65_06685	COG0511	ligase activity, forming carbon-carbon bonds
OPM65_06705	COG1116	anion transmembrane transporter activity
OPM65_06705	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OPM65_06710	COG0745	RESPONSE REGULATOR receiver
OPM65_06720	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OPM65_06720	COG2146	nitrite reductase [NAD(P)H] activity
OPM65_06725	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OPM65_06730	COG0243	molybdopterin cofactor binding
OPM65_06740	COG0243	molybdopterin cofactor binding
OPM65_06745	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OPM65_06760	COG0315	cyclic pyranopterin monophosphate synthase activity
OPM65_06760	COG0521	Mo-molybdopterin cofactor biosynthetic process
OPM65_06765	COG0303	'Molybdopterin
OPM65_06775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OPM65_06780	COG0697	spore germination
OPM65_06800	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
OPM65_06805	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OPM65_06860	COG2204	response regulator
OPM65_06865	COG3852	Histidine kinase
OPM65_06885	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OPM65_06890	COG0575	Belongs to the CDS family
OPM65_06925	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OPM65_06940	COG2137	regulation of response to DNA damage stimulus
OPM65_06950	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OPM65_06955	COG1011	Hydrolase
OPM65_06980	COG1522	sequence-specific DNA binding
OPM65_06990	COG1113	amino acid transport
OPM65_07010	COG0659	secondary active sulfate transmembrane transporter activity
OPM65_07015	COG2135	peptidase activity
OPM65_07030	COG5001	Diguanylate cyclase
OPM65_07030	COG3300	MHYT domain
OPM65_07050	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OPM65_07050	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OPM65_07050	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
OPM65_07055	COG1105	Belongs to the carbohydrate kinase PfkB family
OPM65_07065	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OPM65_07065	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OPM65_07100	COG0024	Methionine aminopeptidase
OPM65_07105	COG0583	DNA-binding transcription factor activity
OPM65_07115	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OPM65_07120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OPM65_07125	COG0517	IMP dehydrogenase activity
OPM65_07125	COG0516	GMP reductase activity
OPM65_07150	COG0552	protein localization to endoplasmic reticulum
OPM65_07160	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
OPM65_07175	COG4890	Cyd operon protein YbgT
OPM65_07180	COG1294	oxidase, subunit
OPM65_07195	COG1585	Membrane protein implicated in regulation of membrane protease activity
OPM65_07205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OPM65_07210	COG4774	siderophore transport
OPM65_07225	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OPM65_07230	COG0569	domain protein
OPM65_07235	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OPM65_07265	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OPM65_07270	COG0542	response to heat
OPM65_07295	COG0446	pyridine nucleotide-disulphide oxidoreductase
OPM65_07295	COG1902	pentaerythritol trinitrate reductase activity
OPM65_07345	COG2323	membrane
OPM65_07350	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OPM65_07360	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OPM65_07365	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OPM65_07370	COG0183	Belongs to the thiolase family
OPM65_07375	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OPM65_07380	COG0596	Alpha beta hydrolase
OPM65_07385	COG2271	Major facilitator Superfamily
OPM65_07390	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OPM65_07395	COG3485	protocatechuate 3,4-dioxygenase
OPM65_07400	COG3485	protocatechuate 3,4-dioxygenase
OPM65_07405	COG0710	3-dehydroquinate dehydratase activity
OPM65_07410	COG3420	alginic acid biosynthetic process
OPM65_07415	COG3659	wide pore channel activity
OPM65_07420	COG4993	Dehydrogenase
OPM65_07430	COG2391	methyltransferase activity
OPM65_07445	COG1414	Transcriptional regulator
OPM65_07450	COG0583	DNA-binding transcription factor activity
OPM65_07455	COG1960	acyl-CoA dehydrogenase activity
OPM65_07480	COG2814	Major facilitator Superfamily
OPM65_07490	COG0154	amidase activity
OPM65_07510	COG4638	Rieske (2fe-2S)
OPM65_07520	COG1028	Short-chain dehydrogenase reductase Sdr
OPM65_07530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OPM65_07540	COG3733	amine oxidase
OPM65_07550	COG1012	belongs to the aldehyde dehydrogenase family
OPM65_07560	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OPM65_07565	COG0183	Belongs to the thiolase family
OPM65_07570	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OPM65_07575	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OPM65_07585	COG4829	muconolactone delta-isomerase
OPM65_07590	COG4948	Mandelate Racemase Muconate Lactonizing
OPM65_07595	COG0583	DNA-binding transcription factor activity
OPM65_07605	COG2186	Transcriptional regulator
OPM65_07625	COG1012	belongs to the aldehyde dehydrogenase family
OPM65_07645	COG1960	acyl-CoA dehydrogenase activity
OPM65_07655	COG3829	transcription factor binding
OPM65_07665	COG3162	membrane
OPM65_07680	COG1012	belongs to the aldehyde dehydrogenase family
OPM65_07695	COG0753	catalase activity
OPM65_07715	COG1846	Transcriptional regulator
OPM65_07720	COG1902	pentaerythritol trinitrate reductase activity
OPM65_07720	COG0446	pyridine nucleotide-disulphide oxidoreductase
OPM65_07730	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OPM65_07760	COG1309	transcriptional regulator
OPM65_07770	COG1335	isochorismatase
OPM65_07775	COG0583	DNA-binding transcription factor activity
OPM65_07785	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OPM65_07785	COG0475	glutathione-regulated potassium exporter activity
OPM65_07795	COG1473	amidohydrolase
OPM65_07805	COG2831	hemolysin activation secretion protein
OPM65_07810	COG3210	domain, Protein
OPM65_07840	COG2188	Transcriptional regulator
OPM65_07855	COG0583	DNA-binding transcription factor activity
OPM65_07885	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OPM65_07915	COG1566	PFAM secretion protein HlyD family protein
OPM65_07930	COG1012	belongs to the aldehyde dehydrogenase family
OPM65_07935	COG0129	dihydroxy-acid dehydratase activity
OPM65_07945	COG0583	DNA-binding transcription factor activity
OPM65_07950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OPM65_07960	COG2084	Dehydrogenase
OPM65_07965	COG2207	Transcriptional regulator
OPM65_07980	COG1064	alcohol dehydrogenase
OPM65_07990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OPM65_07995	COG1120	ATPase activity
OPM65_08015	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OPM65_08135	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OPM65_08185	COG1028	Short-chain dehydrogenase reductase Sdr
OPM65_08200	COG2207	Transcriptional regulator
OPM65_08210	COG2205	protein histidine kinase activity
OPM65_08215	COG0745	RESPONSE REGULATOR receiver
OPM65_08220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OPM65_08225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OPM65_08230	COG1538	Outer membrane efflux protein
OPM65_08240	COG2072	flavoprotein involved in K transport
OPM65_08260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OPM65_08280	COG3539	Fimbrial protein
OPM65_08310	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
OPM65_08320	COG0753	catalase activity
OPM65_08335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OPM65_08395	COG3433	isochorismatase activity
OPM65_08395	COG1535	isochorismatase
OPM65_08400	COG1028	Short-chain dehydrogenase reductase Sdr
OPM65_08405	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OPM65_08410	COG4149	molybdate abc transporter
OPM65_08415	COG0725	ABC transporter, periplasmic molybdate-binding protein
OPM65_08425	COG4638	Rieske (2fe-2S)
OPM65_08430	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
OPM65_08435	COG0543	2 iron, 2 sulfur cluster binding
OPM65_08435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OPM65_08460	COG1028	Short-chain dehydrogenase reductase Sdr
OPM65_08475	COG2207	Transcriptional regulator
OPM65_08485	COG1028	Short-chain dehydrogenase reductase Sdr
OPM65_08490	COG2610	gluconate transmembrane transporter activity
OPM65_08500	COG0583	DNA-binding transcription factor activity
OPM65_08510	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OPM65_08515	COG2031	fatty acid transporter
OPM65_08520	COG0183	Belongs to the thiolase family
OPM65_08525	COG0583	DNA-binding transcription factor activity
OPM65_08530	COG0583	DNA-binding transcription factor activity
OPM65_08545	COG1027	Aspartate ammonia-lyase
OPM65_08555	COG0477	Major facilitator Superfamily
OPM65_08575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OPM65_08580	COG4521	taurine ABC transporter
OPM65_08595	COG2188	Transcriptional regulator
OPM65_08605	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OPM65_08610	COG1733	regulation of RNA biosynthetic process
OPM65_08615	COG3708	Transcriptional regulator
OPM65_08615	COG2207	Transcriptional regulator
OPM65_08630	COG0730	response to heat
OPM65_08645	COG3453	Protein conserved in bacteria
OPM65_08645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OPM65_08655	COG3781	membrane
OPM65_08660	COG1063	alcohol dehydrogenase
OPM65_08670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OPM65_08675	COG0508	dehydrogenase complex catalyzes the overall conversion of
OPM65_08680	COG0022	dehydrogenase e1 component
OPM65_08685	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OPM65_08690	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OPM65_08705	COG3706	GGDEF domain
OPM65_08720	COG0133	tryptophan synthase activity
OPM65_08730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OPM65_08765	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OPM65_08790	COG2226	methyltransferase
OPM65_08845	COG0842	Transport permease protein
OPM65_08850	COG0842	Transport permease protein
OPM65_08855	COG1131	(ABC) transporter
OPM65_08870	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OPM65_08875	COG4773	Receptor
OPM65_08895	COG0730	response to heat
OPM65_08900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OPM65_08920	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OPM65_08935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OPM65_08975	COG4264	IucA IucC family
OPM65_08980	COG4264	IucA IucC family
OPM65_09000	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OPM65_09015	COG1960	acyl-CoA dehydrogenase activity
OPM65_09020	COG1960	acyl-CoA dehydrogenase activity
OPM65_09025	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OPM65_09030	COG2207	Transcriptional regulator
OPM65_09035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OPM65_09040	COG0776	regulation of translation
OPM65_09065	COG0822	iron-sulfur transferase activity
OPM65_09070	COG0316	Belongs to the HesB IscA family
OPM65_09100	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OPM65_09120	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OPM65_09125	COG0702	epimerase
OPM65_09160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OPM65_09170	COG0339	signal peptide processing
OPM65_09220	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OPM65_09225	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OPM65_09255	COG0776	regulation of translation
OPM65_09320	COG0084	hydrolase, TatD family'
OPM65_09340	COG1663	tetraacyldisaccharide 4'-kinase activity
OPM65_09345	COG1132	(ABC) transporter
OPM65_09355	COG0811	peptide transport
OPM65_09360	COG1475	DNA binding
OPM65_09365	COG1192	Involved in chromosome partitioning
OPM65_09375	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OPM65_09390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OPM65_09395	COG0191	fructose-bisphosphate aldolase activity
OPM65_09415	COG0424	maF-like protein
OPM65_09420	COG2850	peptidyl-arginine hydroxylation
OPM65_09430	COG0640	Transcriptional regulator
OPM65_09440	COG3619	membrane
OPM65_09445	COG3122	Protein conserved in bacteria
OPM65_09450	COG1132	(ABC) transporter
OPM65_09470	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OPM65_09475	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OPM65_09485	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OPM65_09485	COG0506	proline dehydrogenase activity
OPM65_09485	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OPM65_09490	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OPM65_09505	COG3698	Phosphodiester glycosidase
OPM65_09515	COG2353	YceI-like domain
OPM65_09525	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OPM65_09570	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OPM65_09570	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OPM65_09595	COG3539	Fimbrial protein
OPM65_09600	COG3121	Chaperone
OPM65_09625	COG0697	spore germination
OPM65_09635	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OPM65_09645	COG0583	DNA-binding transcription factor activity
OPM65_09665	COG1309	transcriptional regulator
OPM65_09680	COG1522	sequence-specific DNA binding
OPM65_09690	COG1126	abc transporter atp-binding protein
OPM65_09695	COG0765	amino acid transport
OPM65_09700	COG0765	amino acid transport
OPM65_09730	COG1464	Belongs to the NlpA lipoprotein family
OPM65_09740	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OPM65_09745	COG2011	ABC-type metal ion transport system permease component
OPM65_09750	COG0012	GTP binding
OPM65_09775	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OPM65_09815	COG0386	Belongs to the glutathione peroxidase family
OPM65_09825	COG0436	Aminotransferase
OPM65_09865	COG3634	alkyl hydroperoxide reductase activity
OPM65_09880	COG0583	DNA-binding transcription factor activity
OPM65_09885	COG0798	PFAM Bile acid sodium symporter
OPM65_09890	COG0640	Transcriptional regulator
OPM65_09905	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OPM65_09915	COG0583	DNA-binding transcription factor activity
OPM65_09925	COG1953	Uracil, thiamine, allantoin
OPM65_09935	COG2175	clavaminate synthase activity
OPM65_09940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OPM65_09945	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
OPM65_09950	COG4521	taurine ABC transporter
OPM65_09960	COG0477	Major facilitator Superfamily
OPM65_09980	COG1271	oxidase subunit
OPM65_09985	COG1294	oxidase, subunit
OPM65_09995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OPM65_10015	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OPM65_10035	COG3052	prosthetic group binding
OPM65_10040	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
OPM65_10050	COG2814	Major facilitator Superfamily
OPM65_10070	COG1346	cytolysis
OPM65_10080	COG0583	DNA-binding transcription factor activity
OPM65_10085	COG0625	glutathione transferase activity
OPM65_10090	COG0625	glutathione transferase activity
OPM65_10095	COG0583	DNA-binding transcription factor activity
OPM65_10110	COG1045	serine acetyltransferase
OPM65_10115	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OPM65_10120	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OPM65_10130	COG1280	lysine exporter protein (LysE YggA)
OPM65_10145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OPM65_10150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OPM65_10155	COG1126	abc transporter atp-binding protein
OPM65_10160	COG0765	amino acid transport
OPM65_10165	COG0765	amino acid transport
OPM65_10185	COG2205	protein histidine kinase activity
OPM65_10185	COG0784	Response regulator, receiver
OPM65_10205	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OPM65_10225	COG1028	Short-chain dehydrogenase reductase Sdr
OPM65_10275	COG0583	DNA-binding transcription factor activity
OPM65_10295	COG0318	PFAM AMP-dependent synthetase and ligase
OPM65_10300	COG1309	transcriptional regulator
OPM65_10305	COG1960	acyl-CoA dehydrogenase activity
OPM65_10310	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OPM65_10315	COG1024	Enoyl-CoA hydratase
OPM65_10320	COG4770	biotin carboxylase activity
OPM65_10330	COG0583	DNA-binding transcription factor activity
OPM65_10345	COG1960	acyl-CoA dehydrogenase activity
OPM65_10355	COG2814	Major facilitator Superfamily
OPM65_10365	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OPM65_10370	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OPM65_10375	COG2814	Major facilitator Superfamily
OPM65_10380	COG1960	acyl-CoA dehydrogenase activity
OPM65_10385	COG1024	Enoyl-CoA hydratase
OPM65_10390	COG1028	Short-chain dehydrogenase reductase Sdr
OPM65_10395	COG1250	3-hydroxyacyl-CoA dehydrogenase
OPM65_10400	COG0183	Belongs to the thiolase family
OPM65_10410	COG2814	Major facilitator Superfamily
OPM65_10420	COG1024	Enoyl-CoA hydratase
OPM65_10435	COG1960	acyl-CoA dehydrogenase activity
OPM65_10440	COG2814	Major facilitator Superfamily
OPM65_10445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OPM65_10450	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OPM65_10465	COG3842	ATPase activity
OPM65_10470	COG1840	ABC-type Fe3 transport system, periplasmic component
OPM65_10480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OPM65_10485	COG1414	Transcriptional regulator
OPM65_10495	COG0583	DNA-binding transcription factor activity
OPM65_10500	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OPM65_10505	COG1012	belongs to the aldehyde dehydrogenase family
OPM65_10515	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OPM65_10525	COG1012	belongs to the aldehyde dehydrogenase family
OPM65_10530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OPM65_10535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OPM65_10540	COG2267	carboxylic ester hydrolase activity
OPM65_10560	COG3038	cytochrome b561
OPM65_10565	COG0753	catalase activity
OPM65_10600	COG2050	protein possibly involved in aromatic compounds catabolism
OPM65_10610	COG3327	negative regulation of DNA-templated transcription, initiation
OPM65_10615	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
OPM65_10620	COG0183	Belongs to the thiolase family
OPM65_10625	COG1250	3-hydroxyacyl-CoA dehydrogenase
OPM65_10630	COG1024	Enoyl-CoA hydratase
OPM65_10635	COG1024	Enoyl-CoA hydratase
OPM65_10640	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OPM65_10645	COG2151	metal-sulfur cluster biosynthetic enzyme
OPM65_10650	COG3396	Phenylacetate-CoA oxygenase
OPM65_10655	COG3460	Phenylacetate-CoA oxygenase
OPM65_10660	COG3396	Phenylacetate-CoA oxygenase
OPM65_10665	COG2030	dehydratase
OPM65_10665	COG1012	belongs to the aldehyde dehydrogenase family
OPM65_10670	COG1760	l-serine dehydratase
OPM65_10675	COG0531	amino acid
OPM65_10680	COG1012	belongs to the aldehyde dehydrogenase family
OPM65_10695	COG0446	pyridine nucleotide-disulphide oxidoreductase
OPM65_10705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OPM65_10725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OPM65_10735	COG0789	Transcriptional regulator
OPM65_10750	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OPM65_10765	COG2807	transmembrane transport
OPM65_10770	COG0590	tRNA wobble adenosine to inosine editing
OPM65_10885	COG1116	anion transmembrane transporter activity
OPM65_10890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OPM65_10900	COG0864	Transcriptional regulator
OPM65_10920	COG2249	NAD(P)H dehydrogenase (quinone) activity
OPM65_10925	COG0439	Biotin carboxylase
OPM65_10940	COG1063	alcohol dehydrogenase
OPM65_10950	COG1309	transcriptional regulator
OPM65_10970	COG0038	chloride channel
OPM65_10975	COG4770	biotin carboxylase activity
OPM65_10995	COG1914	H( )-stimulated, divalent metal cation uptake system
OPM65_11000	COG0583	DNA-binding transcription factor activity
OPM65_11050	COG1250	3-hydroxyacyl-CoA dehydrogenase
OPM65_11070	COG2814	Major facilitator Superfamily
OPM65_11085	COG1560	Kdo2-lipid A biosynthetic process
OPM65_11095	COG5006	permease, DMT superfamily
OPM65_11100	COG1522	sequence-specific DNA binding
OPM65_11115	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OPM65_11125	COG4122	O-methyltransferase activity
OPM65_11155	COG1538	Outer membrane efflux protein
OPM65_11160	COG1137	ATPase activity
OPM65_11165	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
OPM65_11175	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OPM65_11180	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OPM65_11180	COG0517	IMP dehydrogenase activity
OPM65_11215	COG2814	Major facilitator Superfamily
OPM65_11250	COG1278	Cold shock
OPM65_11255	COG1280	lysine exporter protein (LysE YggA)
OPM65_11285	COG1570	exodeoxyribonuclease VII activity
OPM65_11335	COG0583	DNA-binding transcription factor activity
OPM65_11345	COG4638	Rieske (2fe-2S)
OPM65_11350	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
OPM65_11355	COG0633	Ferredoxin
OPM65_11355	COG0543	2 iron, 2 sulfur cluster binding
OPM65_11360	COG1028	Short-chain dehydrogenase reductase Sdr
OPM65_11365	COG3135	benzoate transporter
OPM65_11370	COG2814	Major facilitator Superfamily
OPM65_11385	COG1643	Atp-dependent helicase
OPM65_11390	COG0450	alkyl hydroperoxide reductase
OPM65_11400	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OPM65_11410	COG3634	alkyl hydroperoxide reductase activity
OPM65_11430	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OPM65_11435	COG0625	glutathione transferase activity
OPM65_11445	COG2885	chlorophyll binding
OPM65_11480	COG0542	response to heat
OPM65_11500	COG1765	OsmC-like protein
OPM65_11520	COG0667	Aldo Keto reductase
OPM65_11535	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OPM65_11545	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OPM65_11555	COG0527	aspartate kinase activity
OPM65_11565	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OPM65_11575	COG3038	cytochrome b561
OPM65_11580	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OPM65_11585	COG2252	PERMEase
OPM65_11595	COG2072	flavoprotein involved in K transport
OPM65_11610	COG1741	Belongs to the pirin family
OPM65_11615	COG1309	transcriptional regulator
OPM65_11625	COG0300	oxidoreductase activity
OPM65_11645	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OPM65_11695	COG1012	belongs to the aldehyde dehydrogenase family
OPM65_11715	COG0531	amino acid
OPM65_11725	COG1113	amino acid transport
OPM65_11765	COG3209	COG3209 Rhs family protein
OPM65_11795	COG4269	membrane
OPM65_11810	COG0446	pyridine nucleotide-disulphide oxidoreductase
OPM65_11810	COG1902	pentaerythritol trinitrate reductase activity
OPM65_11820	COG5001	Diguanylate cyclase
OPM65_11820	COG3706	GGDEF domain
OPM65_11820	COG2203	Gaf domain
OPM65_11820	COG4251	negative regulation of phosphorylation
OPM65_11830	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OPM65_11850	COG4172	Belongs to the ABC transporter superfamily
OPM65_11855	COG4239	(ABC) transporter, permease
OPM65_11860	COG4174	ABC transporter (Permease)
OPM65_11870	COG1388	LysM domain
OPM65_11870	COG0741	lytic transglycosylase activity
OPM65_11870	COG1388	LysM domain
OPM65_11870	COG0741	lytic transglycosylase activity
OPM65_11875	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OPM65_11975	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OPM65_12075	COG1610	YqeY-like protein
OPM65_12080	COG4783	chaperone-mediated protein folding
OPM65_12105	COG1286	toxin biosynthetic process
OPM65_12135	COG0778	Nitroreductase
OPM65_12145	COG0513	Belongs to the DEAD box helicase family
OPM65_12170	COG2363	Small membrane protein
OPM65_12200	COG1234	tRNA 3'-trailer cleavage
OPM65_12205	COG2195	Cleaves the N-terminal amino acid of tripeptides
OPM65_12215	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OPM65_12225	COG2819	hydrolase of the alpha beta superfamily
OPM65_12230	COG1960	acyl-CoA dehydrogenase activity
OPM65_12235	COG1301	dicarboxylic acid transport
OPM65_12240	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OPM65_12245	COG3139	Protein of unknown function (DUF1315)
OPM65_12250	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OPM65_12255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OPM65_12265	COG0494	nUDIX hydrolase
OPM65_12275	COG0642	Histidine kinase
OPM65_12290	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OPM65_12300	COG1720	tRNA m6t6A37 methyltransferase activity
OPM65_12315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OPM65_12320	COG0826	peptidase U32
OPM65_12325	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OPM65_12335	COG4598	ABC transporter
OPM65_12340	COG4160	amino acid transport
OPM65_12345	COG4215	(ABC) transporter
OPM65_12360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OPM65_12405	COG1131	(ABC) transporter
OPM65_12410	COG0842	Transport permease protein
OPM65_12425	COG0772	Belongs to the SEDS family
OPM65_12430	COG2951	lytic endotransglycosylase activity
OPM65_12455	COG2207	Transcriptional regulator
OPM65_12470	COG0052	Belongs to the universal ribosomal protein uS2 family
OPM65_12475	COG0024	Methionine aminopeptidase
OPM65_12485	COG2223	nitrite transmembrane transporter activity
OPM65_12495	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OPM65_12500	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OPM65_12505	COG1960	acyl-CoA dehydrogenase activity
OPM65_12520	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OPM65_12525	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OPM65_12530	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OPM65_12550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OPM65_12555	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OPM65_12560	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OPM65_12595	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OPM65_12605	COG0174	glutamine synthetase
OPM65_12620	COG0512	Glutamine amidotransferase of anthranilate synthase
OPM65_12625	COG0308	aminopeptidase N
OPM65_12655	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OPM65_12665	COG0302	gtp cyclohydrolase
OPM65_12690	COG3739	integral membrane protein
OPM65_12705	COG1169	isochorismate synthase
OPM65_12715	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
OPM65_12720	COG1132	(ABC) transporter
OPM65_12725	COG1132	(ABC) transporter
OPM65_12740	COG3433	isochorismatase activity
OPM65_12740	COG1535	isochorismatase
OPM65_12745	COG1021	2,3-dihydroxybenzoate-AMP ligase
OPM65_12750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OPM65_12760	COG4774	siderophore transport
OPM65_12765	COG4607	ABC-type enterochelin transport system periplasmic component
OPM65_12770	COG4604	ABC transporter, ATP-binding protein
OPM65_12775	COG4605	iron ion homeostasis
OPM65_12780	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OPM65_12790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OPM65_12805	COG2964	Protein conserved in bacteria
OPM65_12815	COG1741	Belongs to the pirin family
OPM65_12835	COG1309	transcriptional regulator
OPM65_12845	COG4948	Mandelate Racemase Muconate Lactonizing
OPM65_12850	COG2814	Major facilitator Superfamily
OPM65_12885	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
OPM65_12885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OPM65_12890	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OPM65_12900	COG1012	belongs to the aldehyde dehydrogenase family
OPM65_12910	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OPM65_12915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OPM65_12920	COG0583	DNA-binding transcription factor activity
OPM65_12925	COG1113	amino acid transport
OPM65_12945	COG2508	Transcriptional regulator
OPM65_12945	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OPM65_12980	COG2879	small protein
OPM65_12985	COG1966	Carbon starvation protein
OPM65_13030	COG1067	ATP-dependent peptidase activity
OPM65_13035	COG0583	DNA-binding transcription factor activity
OPM65_13060	COG1686	Belongs to the peptidase S11 family
OPM65_13065	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OPM65_13100	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OPM65_13110	COG0573	inorganic phosphate transmembrane transporter activity
OPM65_13115	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OPM65_13120	COG1113	amino acid transport
OPM65_13125	COG3961	Belongs to the TPP enzyme family
OPM65_13130	COG1522	sequence-specific DNA binding
OPM65_13140	COG0076	glutamate decarboxylase activity
OPM65_13145	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OPM65_13155	COG1309	transcriptional regulator
OPM65_13170	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OPM65_13205	COG0352	thiamine-phosphate diphosphorylase activity
OPM65_13230	COG0612	Peptidase, M16
OPM65_13240	COG1823	symporter activity
OPM65_13245	COG0583	DNA-binding transcription factor activity
OPM65_13250	COG0477	Major facilitator Superfamily
OPM65_13275	COG1187	pseudouridine synthase activity
OPM65_13290	COG1686	Belongs to the peptidase S11 family
OPM65_13295	COG1252	NADH dehydrogenase
OPM65_13305	COG0415	Belongs to the DNA photolyase family
OPM65_13320	COG1215	transferase activity, transferring glycosyl groups
OPM65_13350	COG2070	2-Nitropropane dioxygenase
OPM65_13405	COG0556	nucleotide-excision repair
OPM65_13425	COG0436	Aminotransferase
OPM65_13455	COG4221	oxidoreductase activity
OPM65_13465	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OPM65_13470	COG1381	Involved in DNA repair and RecF pathway recombination
OPM65_13480	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OPM65_13495	COG0681	Belongs to the peptidase S26 family
OPM65_13510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OPM65_13530	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OPM65_13535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OPM65_13540	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
OPM65_13550	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OPM65_13555	COG4208	sulfate ABC transporter
OPM65_13560	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
OPM65_13565	COG0583	DNA-binding transcription factor activity
OPM65_13570	COG4625	pathogenesis
OPM65_13585	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OPM65_13600	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OPM65_13610	COG1051	belongs to the nudix hydrolase family
OPM65_13610	COG1056	cytidyltransferase-related domain
OPM65_13615	COG1024	Enoyl-CoA hydratase
OPM65_13630	COG2814	Major facilitator Superfamily
OPM65_13635	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OPM65_13635	COG0047	phosphoribosylformylglycinamidine synthase activity
OPM65_13655	COG1473	amidohydrolase
OPM65_13660	COG0824	Thioesterase
OPM65_13680	COG0823	Involved in the tonB-independent uptake of proteins
OPM65_13700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OPM65_13745	COG0628	permease
OPM65_13755	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OPM65_13760	COG0596	Alpha beta hydrolase
OPM65_13765	COG0616	signal peptide processing
OPM65_13765	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OPM65_13775	COG0658	competence protein
OPM65_13775	COG2333	competence protein COMEC
OPM65_13780	COG1136	(ABC) transporter
OPM65_13785	COG4591	ABC-type transport system involved in lipoprotein release permease component
OPM65_13820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OPM65_13840	COG0463	Glycosyl transferase, family 2
OPM65_13870	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OPM65_13875	COG1280	lysine exporter protein (LysE YggA)
OPM65_13885	COG0019	diaminopimelate decarboxylase activity
OPM65_13895	COG1113	amino acid transport
OPM65_13910	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
OPM65_13920	COG3339	Conserved Protein
OPM65_13925	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OPM65_13930	COG0243	molybdopterin cofactor binding
OPM65_13935	COG1929	Belongs to the glycerate kinase type-1 family
OPM65_13950	COG0778	Nitroreductase
OPM65_13980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OPM65_13995	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OPM65_14015	COG0741	lytic transglycosylase activity
OPM65_14035	COG0584	glycerophosphoryl diester phosphodiesterase
OPM65_14040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OPM65_14065	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OPM65_14070	COG1597	lipid kinase activity
OPM65_14085	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OPM65_14090	COG0477	Major facilitator Superfamily
OPM65_14140	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OPM65_14145	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OPM65_14170	COG0505	Belongs to the CarA family
OPM65_14190	COG0589	response to stress
OPM65_14205	COG2843	Capsule synthesis protein
OPM65_14225	COG2321	neutral zinc metallopeptidase
OPM65_14230	COG2354	Protein conserved in bacteria
OPM65_14250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OPM65_14275	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OPM65_14280	COG1053	succinate dehydrogenase
OPM65_14285	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OPM65_14290	COG2009	succinate dehydrogenase
OPM65_14330	COG2921	Belongs to the UPF0250 family
OPM65_14335	COG0321	lipoyl(octanoyl) transferase activity
OPM65_14350	COG0531	amino acid
OPM65_14360	COG1733	regulation of RNA biosynthetic process
OPM65_14365	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OPM65_14370	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OPM65_14370	COG1648	precorrin-2 dehydrogenase activity
OPM65_14385	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OPM65_14415	COG0671	phosphoesterase, PA-phosphatase related
OPM65_14420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OPM65_14430	COG1538	Outer membrane efflux protein
OPM65_14435	COG0393	Putative heavy-metal-binding
OPM65_14440	COG0393	Putative heavy-metal-binding
OPM65_14450	COG1028	Short-chain dehydrogenase reductase Sdr
OPM65_14460	COG0525	valine-tRNA ligase activity
OPM65_14480	COG0583	DNA-binding transcription factor activity
OPM65_14485	COG0004	ammonium transporteR
OPM65_14495	COG0642	Histidine kinase
OPM65_14500	COG0745	RESPONSE REGULATOR receiver
OPM65_14505	COG2194	sulfuric ester hydrolase activity
OPM65_14525	COG1752	Esterase of the alpha-beta hydrolase superfamily
OPM65_14540	COG2315	Protein conserved in bacteria
OPM65_14545	COG0142	geranyltranstransferase activity
OPM65_14550	COG2828	Protein conserved in bacteria
OPM65_14555	COG1113	amino acid transport
OPM65_14575	COG2207	Transcriptional regulator
OPM65_14600	COG2249	NAD(P)H dehydrogenase (quinone) activity
OPM65_14610	COG0560	Phosphoserine phosphatase
OPM65_14620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OPM65_14630	COG1530	ribonuclease E activity
OPM65_14635	COG0424	maF-like protein
OPM65_14640	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
OPM65_14645	COG1792	Involved in formation and maintenance of cell shape
OPM65_14650	COG1077	Cell shape determining protein MreB Mrl
OPM65_14655	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OPM65_14665	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OPM65_14695	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
OPM65_14700	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OPM65_14705	COG1752	Esterase of the alpha-beta hydrolase superfamily
OPM65_14710	COG1115	amino acid carrier protein
OPM65_14730	COG2814	Major facilitator Superfamily
OPM65_14735	COG1289	transmembrane transporter activity
OPM65_14745	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OPM65_14785	COG1376	ErfK ybiS ycfS ynhG family protein
OPM65_14790	COG2832	Protein of unknown function (DUF454)
OPM65_14800	COG5510	response to toxic substance
OPM65_14820	COG0840	transmembrane signaling receptor activity
OPM65_14860	COG3422	double-strand break repair
OPM65_14865	COG2824	Alkylphosphonate utilization operon protein PhnA
OPM65_14870	COG3189	MarR family transcriptional regulator
OPM65_14880	COG0354	folic acid binding
OPM65_14885	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OPM65_14895	COG0679	Auxin Efflux Carrier
OPM65_14900	COG1902	pentaerythritol trinitrate reductase activity
OPM65_14920	COG2094	Belongs to the DNA glycosylase MPG family
OPM65_14945	COG1217	gtp-binding protein TYPA
OPM65_14950	COG2233	PERMEase
OPM65_14960	COG0833	amino acid
OPM65_14965	COG1690	Belongs to the RtcB family
OPM65_14975	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
OPM65_14975	COG2885	chlorophyll binding
OPM65_14985	COG0183	Belongs to the thiolase family
OPM65_15005	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OPM65_15025	COG2207	Transcriptional regulator
OPM65_15030	COG0183	Belongs to the thiolase family
OPM65_15060	COG1272	protein, Hemolysin III
OPM65_15065	COG0477	Major facilitator Superfamily
OPM65_15080	COG0450	alkyl hydroperoxide reductase
OPM65_15100	COG0285	dihydrofolate synthase activity
OPM65_15150	COG2096	Adenosyltransferase
OPM65_15170	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OPM65_15175	COG0745	RESPONSE REGULATOR receiver
OPM65_15180	COG2205	protein histidine kinase activity
OPM65_15190	COG1960	acyl-CoA dehydrogenase activity
OPM65_15195	COG1960	acyl-CoA dehydrogenase activity
OPM65_15200	COG0583	DNA-binding transcription factor activity
OPM65_15205	COG0625	glutathione transferase activity
OPM65_15270	COG0438	transferase activity, transferring glycosyl groups
OPM65_15275	COG0463	Glycosyl transferase, family 2
OPM65_15280	COG0726	polysaccharide deacetylase
OPM65_15300	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OPM65_15305	COG2205	protein histidine kinase activity
OPM65_15355	COG1862	Preprotein translocase
OPM65_15365	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OPM65_15370	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OPM65_15380	COG3781	membrane
OPM65_15385	COG0613	PHP domain protein
OPM65_15395	COG2350	Protein conserved in bacteria
OPM65_15425	COG1607	acyl-coa hydrolase
OPM65_15485	COG2199	diguanylate cyclase activity
OPM65_15495	COG1408	metallophosphoesterase
OPM65_15500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OPM65_15510	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OPM65_15530	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OPM65_15535	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OPM65_15550	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OPM65_15560	COG2969	positive regulation of protein catabolic process
OPM65_15580	COG1960	acyl-CoA dehydrogenase activity
OPM65_15585	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OPM65_15600	COG1309	transcriptional regulator
OPM65_15605	COG1960	acyl-CoA dehydrogenase activity
OPM65_15650	COG1183	phosphatidylcholine synthase activity
OPM65_15655	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OPM65_15685	COG1196	nuclear chromosome segregation
OPM65_15685	COG0739	heme binding
OPM65_15685	COG0741	lytic transglycosylase activity
OPM65_15695	COG1702	phosphate starvation-inducible protein PhoH
OPM65_15730	COG1295	ribonuclease BN
OPM65_15735	COG0697	spore germination
OPM65_15740	COG2169	Transcriptional regulator
OPM65_15745	COG0179	Fumarylacetoacetate (FAA) hydrolase
OPM65_15790	COG0557	exoribonuclease II activity
OPM65_15795	COG0339	signal peptide processing
OPM65_15800	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
OPM65_15830	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
OPM65_15835	COG1960	acyl-CoA dehydrogenase activity
OPM65_15990	COG0626	cystathionine gamma-synthase activity
OPM65_15995	COG0433	COG0433 Predicted ATPase
OPM65_16000	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OPM65_16000	COG1017	nitric oxide dioxygenase activity
OPM65_16005	COG1959	2 iron, 2 sulfur cluster binding
OPM65_16020	COG1301	dicarboxylic acid transport
OPM65_16025	COG1946	Acyl-CoA thioesterase
OPM65_16045	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OPM65_16050	COG1040	competence protein
OPM65_16055	COG0494	nUDIX hydrolase
OPM65_16065	COG0598	Magnesium transport protein CorA
OPM65_16075	COG2854	intermembrane phospholipid transfer
OPM65_16085	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OPM65_16090	COG1127	ABC transporter
OPM65_16100	COG0513	Belongs to the DEAD box helicase family
OPM65_16120	COG0408	coproporphyrinogen oxidase activity
OPM65_16135	COG1960	acyl-CoA dehydrogenase activity
OPM65_16145	COG1983	PspC domain protein
OPM65_16150	COG0517	IMP dehydrogenase activity
OPM65_16195	COG0583	DNA-binding transcription factor activity
OPM65_16235	COG1012	belongs to the aldehyde dehydrogenase family
OPM65_16245	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OPM65_16250	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OPM65_16255	COG0833	amino acid
OPM65_16285	COG1192	Involved in chromosome partitioning
OPM65_16290	COG0628	permease
OPM65_16300	COG1289	transmembrane transporter activity
OPM65_16315	COG2249	NAD(P)H dehydrogenase (quinone) activity
OPM65_16320	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OPM65_16330	COG0277	FAD linked oxidase domain protein
OPM65_16335	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OPM65_16360	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OPM65_16365	COG5380	lipid catabolic process
OPM65_16385	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OPM65_16435	COG0194	GDP metabolic process
OPM65_16450	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OPM65_16470	COG3307	-O-antigen
OPM65_16490	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OPM65_16495	COG1704	LemA family
OPM65_16505	COG0493	'glutamate synthase
OPM65_16510	COG0070	glutamate synthase
OPM65_16510	COG0069	glutamate synthase activity
OPM65_16510	COG0067	glutamate synthase
OPM65_16560	COG2226	methyltransferase
OPM65_16575	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OPM65_16580	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OPM65_16625	COG0833	amino acid
OPM65_16710	COG0488	(ABC) transporter
OPM65_16715	COG2873	o-acetylhomoserine
OPM65_16720	COG4221	oxidoreductase activity
OPM65_16725	COG0659	secondary active sulfate transmembrane transporter activity
OPM65_16750	COG0427	acetyl-CoA hydrolase
OPM65_16780	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OPM65_16810	COG2329	Antibiotic biosynthesis monooxygenase
OPM65_16825	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OPM65_16890	COG2249	NAD(P)H dehydrogenase (quinone) activity
OPM65_16895	COG1733	regulation of RNA biosynthetic process
OPM65_16930	COG0667	Aldo Keto reductase
OPM65_16950	COG0583	DNA-binding transcription factor activity
OPM65_16955	COG2814	Major facilitator Superfamily
OPM65_16985	COG1335	isochorismatase
OPM65_16995	COG1012	belongs to the aldehyde dehydrogenase family
OPM65_17000	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OPM65_17010	COG1113	amino acid transport
OPM65_17020	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OPM65_17035	COG2814	Major facilitator Superfamily
OPM65_17045	COG0351	phosphomethylpyrimidine kinase
OPM65_17045	COG0352	thiamine-phosphate diphosphorylase activity
OPM65_17045	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OPM65_17065	COG1309	transcriptional regulator
OPM65_17070	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OPM65_17090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OPM65_17100	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OPM65_17105	COG3162	membrane
OPM65_17110	COG2205	protein histidine kinase activity
OPM65_17110	COG2198	Histidine kinase
OPM65_17110	COG0784	Response regulator, receiver
OPM65_17135	COG3328	transposase activity
OPM65_17140	COG1522	sequence-specific DNA binding
OPM65_17145	COG1335	isochorismatase
OPM65_17150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OPM65_17160	COG0668	transmembrane transport
OPM65_17165	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OPM65_17170	COG1519	Transferase
OPM65_17175	COG1902	pentaerythritol trinitrate reductase activity
OPM65_17195	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OPM65_17220	COG0426	domain, Protein
OPM65_17220	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OPM65_17240	COG2119	membrane
OPM65_17250	COG0508	dehydrogenase complex catalyzes the overall conversion of
OPM65_17260	COG4942	peptidase
OPM65_17275	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OPM65_17285	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OPM65_17305	COG0189	ligase activity
OPM65_17325	COG0708	Exodeoxyribonuclease III
OPM65_17330	COG1393	Belongs to the ArsC family
OPM65_17345	COG3706	GGDEF domain
OPM65_17380	COG2351	hydroxyisourate hydrolase activity
OPM65_17385	COG2233	PERMEase
OPM65_17395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OPM65_17405	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
OPM65_17410	COG1028	Short-chain dehydrogenase reductase Sdr
OPM65_17420	COG3150	esterase
OPM65_17450	COG2918	glutathione biosynthetic process
OPM65_17465	COG2733	membrane
OPM65_17470	COG0436	Aminotransferase
OPM65_17475	COG0534	Mate efflux family protein
OPM65_17575	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OPM65_17580	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OPM65_17590	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OPM65_17595	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OPM65_17610	COG0010	Belongs to the arginase family
OPM65_17640	COG2188	Transcriptional regulator
OPM65_17650	COG0523	cobalamin synthesis protein
OPM65_17660	COG1113	amino acid transport
OPM65_17670	COG0625	glutathione transferase activity
OPM65_17690	COG1683	Conserved Protein
OPM65_17695	COG0534	Mate efflux family protein
OPM65_17700	COG0385	Bile acid
OPM65_17705	COG1335	isochorismatase
OPM65_17710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OPM65_17730	COG2116	formate transmembrane transporter activity
OPM65_17735	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OPM65_17740	COG2133	pyrroloquinoline quinone binding
OPM65_17745	COG2983	Belongs to the UPF0260 family
OPM65_17750	COG5487	UPF0391 membrane protein
OPM65_17765	COG1194	a g-specific adenine glycosylase
OPM65_17780	COG2818	Glycosylase
OPM65_17785	COG1064	alcohol dehydrogenase
OPM65_17790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OPM65_17805	COG0583	DNA-binding transcription factor activity
OPM65_17810	COG0656	L-ascorbic acid biosynthetic process
OPM65_17815	COG2814	Major facilitator Superfamily
OPM65_17850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OPM65_17865	COG2233	PERMEase
OPM65_17870	COG0583	DNA-binding transcription factor activity
OPM65_17905	COG0733	neurotransmitter:sodium symporter activity
OPM65_17945	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OPM65_17950	COG0657	acetylesterase activity
OPM65_17970	COG0583	DNA-binding transcription factor activity
OPM65_18000	COG2951	lytic endotransglycosylase activity
OPM65_18005	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OPM65_18020	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OPM65_18030	COG0671	phosphoesterase, PA-phosphatase related
OPM65_18035	COG0861	Integral membrane protein TerC family
OPM65_18045	COG0754	glutathionylspermidine amidase activity
OPM65_18055	COG0402	S-adenosylhomocysteine deaminase activity
OPM65_18070	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OPM65_18075	COG1230	cation diffusion facilitator family transporter
OPM65_18090	COG0706	membrane insertase activity