locus-tag	class	description
E4K03_00005	ENOG4105C25	Primosomal protein n'
E4K03_00010	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
E4K03_00025	ENOG4105DVC	DnaJ domain protein
E4K03_00030	ENOG4108ZKH	Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity)
E4K03_00035	ENOG4107QUT	magnesium and cobalt transport protein CorA
E4K03_00055	ENOG4107QYX	exodeoxyribonuclease v alpha
E4K03_00060	ENOG4107QKA	exodeoxyribonuclease V beta
E4K03_00065	ENOG4105DSY	exodeoxyribonuclease V, gamma
E4K03_00075	ENOG4105CSR	polyphosphate kinase 2
E4K03_00085	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
E4K03_00100	ENOG41061H0	Monooxygenase
E4K03_00105	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
E4K03_00120	ENOG4105D65	subunit l
E4K03_00125	ENOG4108ZE9	Monovalent cation H antiporter subunit C
E4K03_00130	ENOG4107R4Z	monovalent cation h antiporter subunit d
E4K03_00135	ENOG4105SC1	monovalent cation H antiporter subunit E
E4K03_00140	ENOG4105W4C	monovalent cation H antiporter subunit F
E4K03_00145	ENOG4105KJM	monovalent cation h antiporter subunit g
E4K03_00160	ENOG4105CHV	Transcription elongation factor NusA
E4K03_00185	ENOG4107EJC	Preprotein translocase subunit SecG
E4K03_00210	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
E4K03_00220	ENOG4105C2N	RNA methyltransferase TrmH family group 3
E4K03_00235	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
E4K03_00245	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
E4K03_00275	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
E4K03_00280	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
E4K03_00335	ENOG4107ZXU	DSBA oxidoreductase
E4K03_00350	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
E4K03_00365	ENOG4105D3Y	Na H antiporter
E4K03_00420	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
E4K03_00425	ENOG4105PM1	preprotein translocase subunit SecE
E4K03_00465	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E4K03_00470	ENOG4105TV9	FHA Domain-Containing protein
E4K03_00475	ENOG4105GVR	general secretion pathway protein D
E4K03_00490	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
E4K03_00515	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
E4K03_00520	ENOG4108NEV	two component transcriptional regulator, LytTR family
E4K03_00525	ENOG4108HRK	Histidine kinase
E4K03_00540	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
E4K03_00545	ENOG4105DFG	type I secretion outer membrane protein
E4K03_00550	ENOG4108RNG	Permease of the drug metabolite transporter
E4K03_00575	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
E4K03_00580	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E4K03_00585	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
E4K03_00590	ENOG4105CNI	cell division protein FtsW
E4K03_00605	ENOG4105CE1	Ferrous iron transport protein b
E4K03_00615	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E4K03_00620	ENOG4105T95	Thiol disulfide interChange protein
E4K03_00625	ENOG4105D6E	homoserine dehydrogenase
E4K03_00635	ENOG41061WM	D-Alanyl-D-Alanine
E4K03_00645	ENOG4107TUY	Histidine kinase
E4K03_00650	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E4K03_00655	ENOG4105CN1	protease
E4K03_00660	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
E4K03_00665	ENOG4108K5H	permease YjgP YjgQ family protein
E4K03_00715	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
E4K03_00725	ENOG4105BZU	Histidine kinase
E4K03_00740	ENOG4105C0P	Mg chelatase subunit ChlI
E4K03_00795	ENOG4105PGM	cation diffusion facilitator family transporter
E4K03_00800	ENOG4107YCR	Transcriptional regulator, ARSR family
E4K03_00820	ENOG4108ZIT	Ferredoxin, 2FE-2S
E4K03_00915	ENOG4105CE1	Ferrous iron transport protein b
E4K03_00935	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
E4K03_00940	ENOG4105FB2	class II Aldolase
E4K03_00945	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E4K03_00960	ENOG4105EPF	Outer membrane porin
E4K03_00965	ENOG4105F0N	pyrophosphate phospho-hydrolase
E4K03_00980	ENOG4105CEY	Amp-dependent synthetase and ligase
E4K03_00985	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E4K03_00990	ENOG41079KZ	Major Facilitator Superfamily
E4K03_00995	ENOG4105EN6	Membrane
E4K03_01000	ENOG4105K5B	UPF0225 protein
E4K03_01005	ENOG4105EE5	Membrane protein terC
E4K03_01010	ENOG4108URH	decarboxylase
E4K03_01015	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
E4K03_01025	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
E4K03_01040	ENOG4105CCT	upf0313 protein
E4K03_01060	ENOG4105C6T	cysteine synthase
E4K03_01095	ENOG4105Y7M	Transcriptional regulator, TetR family
E4K03_01130	ENOG4105C79	DNA protecting protein DprA
E4K03_01145	ENOG4108IND	Tetr family transcriptional regulator
E4K03_01150	ENOG4107RTG	Major Facilitator superfamily
E4K03_01160	ENOG4108V06	Glutathione peroxidase
E4K03_01170	ENOG41090VV	Protein of unknown function (DUF2846)
E4K03_01205	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E4K03_01230	ENOG4105FDK	ABC transporter
E4K03_01235	ENOG4105FAV	ABC, transporter
E4K03_01245	ENOG4105EZR	dyp-type peroxidase family protein
E4K03_01250	ENOG4107R1I	NAD-dependent malic enzyme
E4K03_01280	ENOG4105EUB	pirin domain protein
E4K03_01300	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E4K03_01305	ENOG4106MP8	UPF0754 membrane protein
E4K03_01310	ENOG4108VBZ	doxx family
E4K03_01315	ENOG4105DQR	SNARE associated Golgi
E4K03_01330	ENOG4107QJE	Chromosome Partitioning Protein
E4K03_01340	ENOG4107PSF	BolA-like protein
E4K03_01375	ENOG4105CSH	Transporter
E4K03_01380	ENOG4105E39	Enoyl-CoA hydratase
E4K03_01385	ENOG4105E39	Enoyl-CoA hydratase
E4K03_01390	ENOG4105C1G	acyl-Coa dehydrogenase
E4K03_01400	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
E4K03_01405	ENOG4105C26	Dehydrogenase
E4K03_01415	ENOG4105C85	amino acid
E4K03_01420	ENOG4105C85	amino acid
E4K03_01425	ENOG4105M4H	endoribonuclease L-psp
E4K03_01440	ENOG4105EW9	transcriptional regulator AsnC family
E4K03_01475	ENOG4105D3G	Pseudouridine synthase
E4K03_01535	ENOG4108I0Z	Aconitate hydratase
E4K03_01540	ENOG4105BZN	citrate synthase
E4K03_01545	ENOG4105CR4	methylisocitrate lyase
E4K03_01550	ENOG4105DRR	Transcriptional regulator, GntR family
E4K03_01560	ENOG4105CGF	Aromatic amino acid aminotransferase
E4K03_01565	ENOG4105CXG	d-lactate dehydrogenase
E4K03_01575	ENOG41073TP	transcriptional regulator
E4K03_01580	ENOG4105DAA	L-lactate
E4K03_01585	ENOG4107QKV	phosphomannomutase
E4K03_01590	ENOG4105CMR	udp-glucose 4-epimerase
E4K03_01600	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
E4K03_01605	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
E4K03_01610	ENOG4105D3Q	Sugar transferase
E4K03_01615	ENOG4107UKG	Glycosyl transferase, family 4
E4K03_01630	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
E4K03_01655	ENOG4105P7J	Transfers sialic acid from the substrate CMP-sialic acid donor to the terminal beta-D-galactosyl-1,4-acetyl-beta-D- glucosamine on the lacto-N-neotetraose branch of the lipooligosaccharide
E4K03_01660	ENOG4108MY6	biosynthesis protein
E4K03_01665	ENOG4105F0R	Cytidylyltransferase
E4K03_01680	ENOG4105D2T	synthase
E4K03_01685	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
E4K03_01690	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E4K03_01700	ENOG4107QQG	Dehydrogenase
E4K03_01705	ENOG4105DAY	polysaccharide export protein
E4K03_01715	ENOG4105D75	Capsular exopolysaccharide family
E4K03_01720	ENOG4108V1T	peptidylprolyl cis-trans isomerase
E4K03_01725	ENOG4108V1T	peptidylprolyl cis-trans isomerase
E4K03_01730	ENOG4105CJR	Integral membrane protein (MviN
E4K03_01735	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
E4K03_01740	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
E4K03_01750	ENOG4105HSS	phospholipase C
E4K03_01775	ENOG41062JF	Transcriptional regulator
E4K03_01790	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E4K03_01795	ENOG4105UBK	short-chain dehydrogenase reductase
E4K03_01810	ENOG4107QZM	n-acetylglutamate synthase
E4K03_01815	ENOG4105GVF	(ABC) transporter
E4K03_01820	ENOG4105GVF	(ABC) transporter
E4K03_01825	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
E4K03_01830	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
E4K03_01835	ENOG4108VM9	ABC, transporter
E4K03_01840	ENOG4108R86	Transcriptional regulator
E4K03_01845	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
E4K03_01860	ENOG4105DTN	riboflavin biosynthesis protein ribF
E4K03_01865	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
E4K03_01875	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
E4K03_01915	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
E4K03_01980	ENOG4105CVE	Lytic murein transglycosylase
E4K03_01985	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
E4K03_01990	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
E4K03_02005	ENOG4105DFU	Cell wall formation (By similarity)
E4K03_02015	ENOG4105D5G	Transposase
E4K03_02020	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
E4K03_02025	ENOG4105DU1	integral membrane protein, terc
E4K03_02035	ENOG4106032	Glutathionylspermidine synthase
E4K03_02045	ENOG4107QUY	Guanine deaminase
E4K03_02050	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
E4K03_02060	ENOG4105T95	Thiol disulfide interChange protein
E4K03_02065	ENOG4105PGM	cation diffusion facilitator family transporter
E4K03_02080	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
E4K03_02095	ENOG4105VG0	50S ribosomal protein l34
E4K03_02105	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
E4K03_02115	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E4K03_02125	ENOG4105DQR	SNARE associated Golgi
E4K03_02130	ENOG4105C5H	ABC transporter
E4K03_02135	ENOG4108821	RND type efflux pump
E4K03_02140	ENOG4108821	RND type efflux pump
E4K03_02145	ENOG4108821	RND type efflux pump
E4K03_02155	ENOG4105D74	hydrolase
E4K03_02160	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
E4K03_02165	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
E4K03_02215	ENOG4105C8J	)-transporter
E4K03_02225	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
E4K03_02250	ENOG4108W5M	transcriptional regulator
E4K03_02255	ENOG4105C2W	permease
E4K03_02265	ENOG4108IG5	Transcriptional regulator
E4K03_02315	ENOG4105F27	Major Facilitator
E4K03_02320	ENOG4105CV8	reductase
E4K03_02325	ENOG4105HEI	LysR family (Transcriptional regulator
E4K03_02345	ENOG4105DQ4	alcohol dehydrogenase
E4K03_02350	ENOG4108R3E	Dna-3-methyladenine glycosylase i
E4K03_02365	ENOG4105CEN	a g-specific adenine glycosylase
E4K03_02385	ENOG4108ZZ3	UPF0260 protein
E4K03_02395	ENOG4105D1H	recombination factor protein RarA
E4K03_02400	ENOG4105S64	Formate nitrite transporter
E4K03_02420	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E4K03_02440	ENOG4105C09	Bile acid
E4K03_02445	ENOG4107QI1	Mate efflux family protein
E4K03_02450	ENOG4105EWC	Purine nucleoside phosphorylase
E4K03_02470	ENOG4108RXX	maleylacetoacetate isomerase
E4K03_02480	ENOG4105C85	amino acid
E4K03_02490	ENOG4105CKI	cobalamin synthesis protein
E4K03_02500	ENOG4105CZE	histidine utilization repressor
E4K03_02505	ENOG41090B9	response to stress
E4K03_02520	ENOG4105C85	amino acid
E4K03_02530	ENOG41088SP	formiminoglutamate hydrolase
E4K03_02540	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
E4K03_02545	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
E4K03_02550	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
E4K03_02560	ENOG4108ZAI	phosphatidylglycerophosphatase a
E4K03_02565	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
E4K03_02580	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
E4K03_02630	ENOG4105KHC	sulfurtransferase
E4K03_02640	ENOG4107SCA	Formamidase (EC 3.5.1.49)
E4K03_02655	ENOG4105BZU	Histidine kinase
E4K03_02660	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E4K03_02675	ENOG4107QJQ	Mate efflux family protein
E4K03_02680	ENOG4105CHM	Aminotransferase
E4K03_02685	ENOG4106BRA	Membrane
E4K03_02700	ENOG4105D9M	gamma-glutamylcysteine synthetase
E4K03_02735	ENOG4105IPS	esterase
E4K03_02740	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E4K03_02745	ENOG4108Z2U	ureidoglycolate hydrolase
E4K03_02755	ENOG41061H0	Monooxygenase
E4K03_02770	ENOG41084YZ	Hydrolase
E4K03_02800	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
E4K03_02805	ENOG4105BZU	Histidine kinase
E4K03_02820	ENOG4105KUZ	arsenate reductase
E4K03_02825	ENOG4105CGK	Exodeoxyribonuclease III
E4K03_02860	ENOG4105D7Z	glutathione synthase
E4K03_02880	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
E4K03_02885	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
E4K03_02890	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
E4K03_02905	ENOG41063SB	peptidase
E4K03_02910	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
E4K03_02915	ENOG4107QSN	dihydrolipoamide acetyltransferase
E4K03_02930	ENOG4105E0K	tonB-dependent siderophore receptor
E4K03_02945	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
E4K03_02960	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
E4K03_02980	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E4K03_02985	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
E4K03_02995	ENOG4105D64	Mechanosensitive ion channel
E4K03_03005	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E4K03_03010	ENOG4108W2Y	isochorismatase
E4K03_03020	ENOG4105FBW	Monooxygenase
E4K03_03025	ENOG4108UZX	fmn reductase
E4K03_03040	ENOG4105BZU	Histidine kinase
E4K03_03045	ENOG41062QD	Membrane
E4K03_03050	ENOG4107QN1	sodium solute
E4K03_03060	ENOG4105C94	Transporter
E4K03_03070	ENOG4105BZU	Histidine kinase
E4K03_03075	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
E4K03_03080	ENOG4108WUH	Transcriptional regulator, TetR family
E4K03_03085	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
E4K03_03095	ENOG4105RA2	Membrane
E4K03_03100	ENOG4105DWF	phosphomethylpyrimidine kinase
E4K03_03110	ENOG4107RDB	Major Facilitator
E4K03_03115	ENOG4108UUM	single-stranded DNA-binding protein
E4K03_03125	ENOG4108UMN	azlc family
E4K03_03135	ENOG4105C85	amino acid
E4K03_03145	ENOG4108JPW	Aminotransferase
E4K03_03150	ENOG4105C26	Dehydrogenase
E4K03_03160	ENOG4105CHJ	isochorismatase hydrolase
E4K03_03165	ENOG4105EUB	pirin domain protein
E4K03_03195	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
E4K03_03400	ENOG4105CDU	Replicative dna helicase
E4K03_03490	ENOG4105CUV	Homoserine Kinase
E4K03_03505	ENOG41061CK	Antibiotic biosynthesis monooxygenase
E4K03_03525	ENOG4105BZ1	(ABC) transporter
E4K03_03545	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
E4K03_03575	ENOG4105CYC	Transferase
E4K03_03585	ENOG4105E0F	Histidine kinase
E4K03_03590	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
E4K03_03605	ENOG4105CHH	sulfate transporter
E4K03_03610	ENOG4105PDP	Short chain dehydrogenase
E4K03_03620	ENOG4105C5H	ABC transporter
E4K03_03725	ENOG4108IQI	permease
E4K03_03750	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
E4K03_03765	ENOG4105CJN	penicillin-binding protein
E4K03_03770	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
E4K03_03775	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
E4K03_03790	ENOG4105DHI	Methyltransferase
E4K03_03795	ENOG4108JQC	penicillin-binding protein 1A
E4K03_03850	ENOG4105CBC	glutamate synthase
E4K03_03855	ENOG4105BZ8	glutamate synthase
E4K03_03865	ENOG4108V0P	LemA family
E4K03_03870	ENOG4105HA9	of methanol dehydrogenase type
E4K03_03895	ENOG4108YSG	O-Antigen polymerase
E4K03_03900	ENOG4108UQY	Iron-storage protein
E4K03_03910	ENOG4105KME	endoribonuclease L-psp
E4K03_03915	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E4K03_03930	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
E4K03_03980	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
E4K03_03995	ENOG4107IFA	Lipase (EC 3.1.1.3)
E4K03_04000	ENOG4105MGK	May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity)
E4K03_04005	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
E4K03_04030	ENOG4108JQ1	Dehydrogenase
E4K03_04035	ENOG4105CQB	FAD linked oxidase domain protein
E4K03_04045	ENOG4105VRH	Antibiotic biosynthesis monooxygenase
E4K03_04050	ENOG4105NF4	modulator of drug activity
E4K03_04060	ENOG4107QF7	multi-drug
E4K03_04065	ENOG4105EM2	membrane
E4K03_04070	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
E4K03_04075	ENOG4105IPI	Membrane
E4K03_04080	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
E4K03_04110	ENOG4108IQI	permease
E4K03_04115	ENOG4105D82	Glutamate dehydrogenase
E4K03_04120	ENOG4105C8Y	Acetylornithine aminotransferase
E4K03_04130	ENOG4105C26	Dehydrogenase
E4K03_04155	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
E4K03_04215	ENOG4105W87	Cbs domain
E4K03_04220	ENOG41067S9	phage shock protein C, PspC
E4K03_04230	ENOG4105CSU	acyl-Coa dehydrogenase
E4K03_04245	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
E4K03_04260	ENOG4105ECY	inositol monophosphatase
E4K03_04265	ENOG4105C1J	atp-dependent rna helicase
E4K03_04275	ENOG4105DHJ	ABC, transporter
E4K03_04280	ENOG4105CY3	ABC transporter, permease
E4K03_04290	ENOG4105E3I	toluene tolerance
E4K03_04300	ENOG4105D7N	magnesium and cobalt transport protein CorA
E4K03_04305	ENOG4108URH	decarboxylase
E4K03_04315	ENOG4105MJ2	Competence protein
E4K03_04320	ENOG4105CB5	ATP-dependent DNA helicase recG
E4K03_04340	ENOG4105C29	acyl-CoA thioesterase
E4K03_04345	ENOG4105CK2	sodium dicarboxylate symporter
E4K03_04360	ENOG4105KPV	Transcriptional regulator
E4K03_04375	ENOG4105D7A	ATP-binding protein
E4K03_04380	ENOG4105C28	cystathionine
E4K03_04385	ENOG41089BK	Glutamine amido-transferase
E4K03_04495	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
E4K03_04500	ENOG41067V7	50S ribosomal protein L36
E4K03_04510	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
E4K03_04535	ENOG4105C1G	acyl-Coa dehydrogenase
E4K03_04570	ENOG4105VKU	nucleicacid-binding protein
E4K03_04575	ENOG4105DGW	oligopeptidase A
E4K03_04580	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
E4K03_04625	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
E4K03_04630	ENOG4108K2B	transcriptional regulator
E4K03_04640	ENOG4107S2Z	UPF0761 membrane protein
E4K03_04645	ENOG4105CS1	NAD(P)H quinone oxidoreductase
E4K03_04675	ENOG4105C9A	Phoh family
E4K03_04685	ENOG4105E4C	Lytic transglycosylase catalytic
E4K03_04715	ENOG4105D6S	protein involved in catabolism of external DNA
E4K03_04720	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
E4K03_04765	ENOG4105C1G	acyl-Coa dehydrogenase
E4K03_04770	ENOG4108RZE	Tetr family transcriptional regulator
E4K03_04785	ENOG4107QX3	carboxylase
E4K03_04790	ENOG4105C1G	acyl-Coa dehydrogenase
E4K03_04810	ENOG4105KB2	stringent starvation protein b
E4K03_04815	ENOG4107MKT	Stringent starvation protein a
E4K03_04820	ENOG4108UJD	30S ribosomal protein S9
E4K03_04830	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
E4K03_04835	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
E4K03_04840	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
E4K03_04870	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
E4K03_04880	ENOG4107RZC	phospholipase d
E4K03_04890	ENOG4105UYK	outer membrane protein a
E4K03_04895	ENOG4108KHX	Diguanylate cyclase
E4K03_04930	ENOG4107QN2	dihydrolipoyl dehydrogenase
E4K03_04940	ENOG4107QPB	Beta-lactamase domain protein
E4K03_04955	ENOG4105NAU	thioesterase Superfamily protein
E4K03_04985	ENOG4105K9H	YciI-like protein
E4K03_04995	ENOG4105DB7	PHP domain protein
E4K03_05000	ENOG4105FFC	UPF0187 protein
E4K03_05010	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
E4K03_05020	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E4K03_05025	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E4K03_05030	ENOG4105VIE	preprotein translocase, subunit YajC
E4K03_05065	ENOG4105BZU	Histidine kinase
E4K03_05070	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
E4K03_05075	ENOG4105CM2	brancheD-chain amino acid aminotransferase
E4K03_05085	ENOG4107BJW	polysaccharide deacetylase
E4K03_05090	ENOG4107TYR	Glycosyl Transferase
E4K03_05100	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
E4K03_05105	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
E4K03_05115	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
E4K03_05145	ENOG4105UGU	tonB-dependent Receptor
E4K03_05165	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
E4K03_05170	ENOG4105CSU	acyl-Coa dehydrogenase
E4K03_05175	ENOG4105CSU	acyl-Coa dehydrogenase
E4K03_05185	ENOG4105EB3	Histidine kinase
E4K03_05190	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
E4K03_05195	ENOG4105CNG	UPF0061 protein
E4K03_05215	ENOG4108WBT	adenosyltransferase
E4K03_05230	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
E4K03_05265	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
E4K03_05285	ENOG4105D3R	alkyl hydroperoxide reductase
E4K03_05305	ENOG4108UT2	hemolysin iii
E4K03_05335	ENOG4105CHU	acetyl-coa acetyltransferase
E4K03_05340	ENOG4108R6W	Transcriptional regulator, ARAC family
E4K03_05350	ENOG4105TW1	Carbohydrate-selective porin OprB
E4K03_05355	ENOG4105DZG	Dehydrogenase
E4K03_05360	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
E4K03_05370	ENOG410814C	multidrug resistance protein
E4K03_05380	ENOG4105CHU	acetyl-coa acetyltransferase
E4K03_05390	ENOG4108WHA	ompa motb domain protein
E4K03_05395	ENOG4105E0Y	RtcB Protein
E4K03_05400	ENOG4108IQI	permease
E4K03_05410	ENOG4105C2W	permease
E4K03_05430	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
E4K03_05440	ENOG4108VX5	3-methyladenine DNA glycosylase
E4K03_05445	ENOG4105CHB	tonB-dependent Receptor
E4K03_05450	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E4K03_05455	ENOG4108N2Y	auxin Efflux
E4K03_05465	ENOG4105T95	Thiol disulfide interChange protein
E4K03_05470	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
E4K03_05485	ENOG4105C2W	permease
E4K03_05490	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
E4K03_05495	ENOG4107YYT	May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity)
E4K03_05500	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
E4K03_05505	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
E4K03_05510	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
E4K03_05515	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
E4K03_05520	ENOG4105K78	MarR family Transcriptional regulator
E4K03_05525	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
E4K03_05530	ENOG4105KWI	UPF0339 protein
E4K03_05555	ENOG4108UNF	response regulator
E4K03_05560	ENOG4105M3Z	response regulator
E4K03_05565	ENOG4108ZGA	chew protein
E4K03_05570	ENOG4105C8Q	Methyl-accepting chemotaxis
E4K03_05590	ENOG4106HKS	Entericidin EcnA/B family
E4K03_05600	ENOG4105WD1	Membrane
E4K03_05605	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
E4K03_05645	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
E4K03_05655	ENOG4105EM2	membrane
E4K03_05660	ENOG4105C2C	drug resistance transporter, Bcr CflA
E4K03_05680	ENOG4105BZG	amino acid carrier protein
E4K03_05685	ENOG4105D78	K07001 NTE family protein
E4K03_05690	ENOG4105C7B	Threonine dehydratase
E4K03_05705	ENOG4105C9K	Endothelin-converting enzyme 1
E4K03_05730	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
E4K03_05740	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
E4K03_05745	ENOG4105DFF	Rod shape-determining protein mreb
E4K03_05750	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
E4K03_05755	ENOG4105VQ7	Rod shape-determining protein MreD
E4K03_05760	ENOG4108Z03	MAF-like protein
E4K03_05765	ENOG4105C03	ribonuclease
E4K03_05775	ENOG4105D8T	Acyltransferase
E4K03_05785	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
E4K03_05795	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
E4K03_05820	ENOG4105CF7	AraC family transcriptional regulator
E4K03_05840	ENOG4105C85	amino acid
E4K03_05845	ENOG4105C7F	AcnD-accessory protein PrpF
E4K03_05850	ENOG4105CTB	Polyprenyl synthetase
E4K03_05855	ENOG4105MSB	protein, conserved in bacteria
E4K03_05870	ENOG4105D78	K07001 NTE family protein
E4K03_05890	ENOG4105DIJ	Phosphoethanolamine transferase
E4K03_05895	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E4K03_05900	ENOG4105DHQ	Histidine kinase
E4K03_05925	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
E4K03_05945	ENOG4105K8R	UPF0145 protein
E4K03_05950	ENOG4105K8R	UPF0145 protein
E4K03_05955	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E4K03_05960	ENOG4105BZS	acriflavin resistance protein
E4K03_05965	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
E4K03_05970	ENOG410841Q	phosphoesterase PA-phosphatase related protein
E4K03_06000	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
E4K03_06015	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
E4K03_06020	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
E4K03_06025	ENOG4105KVH	Transcriptional regulator
E4K03_06035	ENOG4105CUB	amino acid
E4K03_06050	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
E4K03_06055	ENOG41084BA	UPF0250 protein
E4K03_06060	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E4K03_06090	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
E4K03_06095	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
E4K03_06105	ENOG4105E33	succinate dehydrogenase
E4K03_06120	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
E4K03_06125	ENOG4105C7S	Dehydrogenase
E4K03_06130	ENOG4107QN2	dihydrolipoyl dehydrogenase
E4K03_06140	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
E4K03_06150	ENOG4105CKW	Inner membrane protein yedI
E4K03_06155	ENOG4105CGZ	zinc metallopeptidase
E4K03_06160	ENOG4105EEQ	Na H antiporter
E4K03_06245	ENOG4105PNM	synthesis protein
E4K03_06260	ENOG41080TK	Universal stress protein
E4K03_06270	ENOG4108UQ8	endoribonuclease L-psp
E4K03_06275	ENOG4108IG5	Transcriptional regulator
E4K03_06285	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
E4K03_06290	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
E4K03_06305	ENOG4105HBR	Rna-binding protein
E4K03_06315	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
E4K03_06320	ENOG4105EEI	dihydropteroate synthase
E4K03_06370	ENOG4105CSH	Transporter
E4K03_06375	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
E4K03_06380	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
E4K03_06395	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
E4K03_06410	ENOG41080IJ	Diacylglycerol kinase
E4K03_06420	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
E4K03_06425	ENOG4105BZS	acriflavin resistance protein
E4K03_06440	ENOG4105E4C	Lytic transglycosylase catalytic
E4K03_06465	ENOG4108RRZ	Transcription elongation factor GreB
E4K03_06480	ENOG4105CEY	Amp-dependent synthetase and ligase
E4K03_06510	ENOG4105YCT	UPF0386 protein
E4K03_06545	ENOG4105BZW	Glycerate kinase
E4K03_06550	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
E4K03_06555	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
E4K03_06570	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
E4K03_06580	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
E4K03_06585	ENOG4105C85	amino acid
E4K03_06595	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
E4K03_06605	ENOG4105N14	lysine exporter protein LysE YggA
E4K03_06610	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E4K03_06615	ENOG4105BZJ	Electron transfer flavoprotein
E4K03_06620	ENOG4105C10	Electron transfer flavoprotein
E4K03_06625	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E4K03_06660	ENOG4107KET	secretion protein, HlyD family
E4K03_06690	ENOG4105D60	lipoprotein releasing system transmembrane protein
E4K03_06695	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
E4K03_06700	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
E4K03_06710	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
E4K03_06715	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
E4K03_06720	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
E4K03_06730	ENOG4105C02	permease
E4K03_06780	ENOG4105KCK	Peptidoglycan-associated lipoprotein
E4K03_06785	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
E4K03_06795	ENOG4105M8F	Biopolymer transport protein exbD tolR
E4K03_06800	ENOG4105E02	MotA TolQ exbB proton channel
E4K03_06805	ENOG4107YD3	Thioesterase
E4K03_06810	ENOG4105CH2	amidohydrolase
E4K03_06830	ENOG4108ETH	Formylglycinamide ribotide synthetase
E4K03_06835	ENOG4105C2C	drug resistance transporter, Bcr CflA
E4K03_06840	ENOG4105EGD	dinuclear metal center protein, YbgI family
E4K03_06845	ENOG4108UKI	Enoyl-CoA hydratase
E4K03_06860	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E4K03_06875	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
E4K03_06880	ENOG4107VRB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
E4K03_06905	ENOG4107R11	Transcriptional regulator
E4K03_06910	ENOG4108IJ6	ABC transporter
E4K03_06920	ENOG4108I5D	sulfate abc transporter
E4K03_06930	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
E4K03_06935	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
E4K03_06940	ENOG4105HHA	aminodeoxychorismate lyase
E4K03_06955	ENOG4108IYU	L-aspartate oxidase
E4K03_06960	ENOG4105C0H	protease
E4K03_06975	ENOG4105C3F	Signal peptidase i
E4K03_06990	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
E4K03_07000	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
E4K03_07005	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
E4K03_07010	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
E4K03_07015	ENOG4105EMU	Dehydrogenase
E4K03_07055	ENOG4105BZU	Histidine kinase
E4K03_07065	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
E4K03_07075	ENOG4105DTR	rard protein
E4K03_07110	ENOG4107QS8	(LipO)protein
E4K03_07115	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
E4K03_07120	ENOG4105EA8	2-Nitropropane dioxygenase
E4K03_07150	ENOG4107R8N	Glycosyl transferase, family 2
E4K03_07165	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
E4K03_07170	ENOG4108YZY	peptidylprolyl cis-trans isomerase
E4K03_07175	ENOG4105CEP	NADH dehydrogenase
E4K03_07180	ENOG4105DZ1	carboxypeptidase
E4K03_07190	ENOG4105E9K	Isocitrate dehydrogenase
E4K03_07195	ENOG4108R99	pseudouridine synthase
E4K03_07220	ENOG4105CBP	Major Facilitator
E4K03_07225	ENOG4105EGI	Transcriptional regulator
E4K03_07230	ENOG4108ETY	sodium dicarboxylate symporter
E4K03_07235	ENOG4105JAB	phenazine biosynthesis protein, phzf family
E4K03_07265	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
E4K03_07280	ENOG4105D3G	Pseudouridine synthase
E4K03_07285	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
E4K03_07300	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
E4K03_07310	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
E4K03_07325	ENOG4108JPW	Aminotransferase
E4K03_07330	ENOG4105DY8	decarboxylase
E4K03_07340	ENOG4105F7P	transcriptional regulator AsnC family
E4K03_07345	ENOG4107RA9	decarboxylase
E4K03_07350	ENOG4105C85	amino acid
E4K03_07355	ENOG4105CVA	phosphate
E4K03_07360	ENOG4105C8U	phosphate abc transporter
E4K03_07370	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
E4K03_07375	ENOG4105ERU	peptidase
E4K03_07390	ENOG4107QTF	adenylosuccinate lyase
E4K03_07410	ENOG4108Z0R	Transferase
E4K03_07415	ENOG4105DZ1	carboxypeptidase
E4K03_07435	ENOG4108K5P	(LipO)protein
E4K03_07440	ENOG4105EJC	lysr family transcriptional regulator
E4K03_07445	ENOG4105DAN	ATP-dependent protease
E4K03_07460	ENOG4105DHU	Bile acid
E4K03_07470	ENOG41066DG	(EAL) domain protein
E4K03_07480	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
E4K03_07490	ENOG4105D22	carbon starvation protein
E4K03_07495	ENOG4105VCD	cytoplasmic protein
E4K03_07515	ENOG4105D5G	Transposase
E4K03_07540	ENOG4105C2I	pirin domain protein
E4K03_07550	ENOG4105WWK	YheO domain protein
E4K03_07565	ENOG4105CEY	Amp-dependent synthetase and ligase
E4K03_07580	ENOG4108IPW	abc transporter atp-binding protein
E4K03_07600	ENOG4105C0W	non-ribosomal peptide synthetase
E4K03_07605	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
E4K03_07610	ENOG4105WQI	isochorismatase
E4K03_07625	ENOG4105BZ1	(ABC) transporter
E4K03_07660	ENOG4105NX3	Membrane
E4K03_07680	ENOG4105EUJ	GTP cyclohydrolase i
E4K03_07690	ENOG4105C7W	Xanthine dehydrogenase
E4K03_07720	ENOG4105CD8	aminopeptidase N
E4K03_07725	ENOG4105DDQ	anthranilate synthase
E4K03_07755	ENOG4105DUX	Transporter
E4K03_07760	ENOG4105C5F	glutamine synthetase
E4K03_07770	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
E4K03_07805	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
E4K03_07810	ENOG4107QNR	UPF0135 protein
E4K03_07815	ENOG4105C0H	protease
E4K03_07825	ENOG4105C6K	Malic enzyme
E4K03_07830	ENOG4105BZU	Histidine kinase
E4K03_07840	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
E4K03_07845	ENOG4105SYT	Methylenetetrahydrofolate reductase
E4K03_07850	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
E4K03_07865	ENOG4107QPN	acyl-Coa dehydrogenase
E4K03_07870	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
E4K03_07875	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
E4K03_07885	ENOG4107RNU	major facilitator superfamily MFS_1
E4K03_07895	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
E4K03_07900	ENOG4105CE9	30S ribosomal protein S2
E4K03_07940	ENOG4105CVE	Lytic murein transglycosylase
E4K03_07945	ENOG4105CNI	cell division protein FtsW
E4K03_07960	ENOG4105E3A	(ABC) transporter
E4K03_07965	ENOG4105DA5	(ABC) transporter
E4K03_08000	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E4K03_08010	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
E4K03_08025	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
E4K03_08030	ENOG4105CFP	Peptidase U32
E4K03_08035	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
E4K03_08040	ENOG4105JAB	phenazine biosynthesis protein, phzf family
E4K03_08045	ENOG4105DP0	ferredoxin-NADP reductase
E4K03_08050	ENOG4108R96	Methyltransferase, YaeB family
E4K03_08060	ENOG4107QHF	type ii secretion system protein e
E4K03_08070	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E4K03_08075	ENOG4105DHQ	Histidine kinase
E4K03_08085	ENOG4105M6F	mutator MutT protein
E4K03_08095	ENOG4105BZ4	penicillin-binding protein
E4K03_08100	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
E4K03_08105	ENOG4105VUT	cytoplasmic protein
E4K03_08120	ENOG4105CK2	sodium dicarboxylate symporter
E4K03_08125	ENOG4105C1G	acyl-Coa dehydrogenase
E4K03_08135	ENOG4105CQC	Prephenate dehydratase
E4K03_08140	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
E4K03_08150	ENOG4105CIN	aminoacyl-histidine dipeptidase
E4K03_08155	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
E4K03_08185	ENOG4105M08	Membrane
E4K03_08190	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E4K03_08200	ENOG4105VEQ	Cold shock protein
E4K03_08205	ENOG4105C1J	atp-dependent rna helicase
E4K03_08215	ENOG41069NU	Nitroreductase
E4K03_08250	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
E4K03_08265	ENOG4105C5I	Dehydrogenase
E4K03_08270	ENOG4105ERG	peptidase m48, ste24p
E4K03_08275	ENOG4105KTH	gatB Yqey
E4K03_08280	ENOG4105VCC	30S ribosomal protein S21
E4K03_08305	ENOG4105D9P	serine threonine protein kinase
E4K03_08330	ENOG4105EVZ	LysR family transcriptional regulator
E4K03_08335	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
E4K03_08340	ENOG4105C26	Dehydrogenase
E4K03_08375	ENOG4105H4F	exported protein
E4K03_08420	ENOG4105D6U	Sodium Glutamate Symporter
E4K03_08430	ENOG4105JXH	GntR family transcriptional regulator
E4K03_08480	ENOG4105CSH	Transporter
E4K03_08505	ENOG4105F1S	paraquat-inducible protein a
E4K03_08510	ENOG4105DY2	Paraquat-inducible protein b
E4K03_08525	ENOG4105C3M	thioredoxin reductase
E4K03_08560	ENOG4105CK2	sodium dicarboxylate symporter
E4K03_08570	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
E4K03_08575	ENOG4108UMI	ABC transporter, permease
E4K03_08580	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
E4K03_08590	ENOG4105C12	Phosphoribosylglycinamide synthetase
E4K03_08595	ENOG4105DC1	bifunctional purine biosynthesis protein purh
E4K03_08600	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
E4K03_08650	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
E4K03_08655	ENOG4105CDU	Replicative dna helicase
E4K03_08680	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
E4K03_08685	ENOG4105CCU	oxidase (Subunit III)
E4K03_08690	ENOG4105BZ9	Cytochrome C oxidase, subunit I
E4K03_08695	ENOG4105E2S	oxidase) subunit II
E4K03_08720	ENOG4107BJW	polysaccharide deacetylase
E4K03_08725	ENOG4105CND	Glycosyl transferase, family 2
E4K03_08730	ENOG4106FQ9	Biofilm PGA synthesis protein PgaD
E4K03_08740	ENOG4105DEN	Luciferase family
E4K03_08760	ENOG4105CC0	LysR family Transcriptional regulator
E4K03_08775	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
E4K03_08780	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
E4K03_08785	ENOG4105GVF	(ABC) transporter
E4K03_08800	ENOG4105C1G	acyl-Coa dehydrogenase
E4K03_08810	ENOG4108MEJ	flavin reductase domain protein
E4K03_08815	ENOG4105D06	uba thif-type nad fad binding protein
E4K03_08835	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
E4K03_08840	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
E4K03_08850	ENOG4105C08	Histidine kinase
E4K03_08855	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
E4K03_08860	ENOG4105CFQ	glutamine synthetase
E4K03_08875	ENOG4107S74	Lysophospholipid transporter LplT
E4K03_08880	ENOG4105CFU	surface antigen
E4K03_08900	ENOG4107QIJ	Aconitate hydratase 2
E4K03_08910	ENOG4105EYW	Ion transport protein
E4K03_08915	ENOG4105F27	Major Facilitator
E4K03_08930	ENOG4105DZ2	Transcriptional regulator
E4K03_08965	ENOG4105K8N	protein family UPF0079, ATPase
E4K03_08970	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
E4K03_08980	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
E4K03_08985	ENOG4108TZV	Membrane
E4K03_08990	ENOG4108RCM	Nitroreductase
E4K03_09015	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E4K03_09020	ENOG4107FQ9	ethanolamine ammonia-lyase
E4K03_09025	ENOG4105CPD	ethanolamine ammonia-lyase
E4K03_09030	ENOG4107R55	ethanolamine transporter
E4K03_09040	ENOG4107RR1	TRANSCRIPTIONal
E4K03_09050	ENOG4105C0A	alcohol dehydrogenase
E4K03_09055	ENOG4107QUV	Domain protein
E4K03_09065	ENOG41086D8	Transcriptional regulator
E4K03_09085	ENOG4105CD8	aminopeptidase N
E4K03_09110	ENOG4108D1K	outer membrane usher protein
E4K03_09135	ENOG4105G7T	Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity)
E4K03_09140	ENOG4105EW9	transcriptional regulator AsnC family
E4K03_09155	ENOG4105R8C	Transcriptional regulator
E4K03_09165	ENOG4105CUY	Mechanosensitive ion channel
E4K03_09195	ENOG4105CNM	Receptor
E4K03_09230	ENOG41081QV	Universal stress protein
E4K03_09245	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
E4K03_09255	ENOG4105DKK	Benzoate
E4K03_09260	ENOG4105EW9	transcriptional regulator AsnC family
E4K03_09265	ENOG4108NIW	Leucine export protein LeuE
E4K03_09270	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
E4K03_09275	ENOG4105C5Q	Transcriptional regulator
E4K03_09285	ENOG4105CHU	acetyl-coa acetyltransferase
E4K03_09290	ENOG4105CHR	reductase
E4K03_09315	ENOG4107QMP	dna polymerase iii subunits gamma and tau
E4K03_09320	ENOG4105HSS	phospholipase C
E4K03_09330	ENOG4105C0A	alcohol dehydrogenase
E4K03_09360	ENOG4105CBC	glutamate synthase
E4K03_09725	ENOG4105DIJ	Phosphoethanolamine transferase
E4K03_09730	ENOG4105D8G	Major Facilitator superfamily
E4K03_09740	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
E4K03_09745	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
E4K03_09770	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E4K03_09780	ENOG4107QZF	nitrite reductase NADPH large subunit
E4K03_09785	ENOG4108IFG	nitrite reductase, (NAD(P)H)
E4K03_09805	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E4K03_09820	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E4K03_09825	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
E4K03_09835	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
E4K03_09840	ENOG4105T38	integral membrane protein
E4K03_09860	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
E4K03_09865	ENOG4105CMR	udp-glucose 4-epimerase
E4K03_09925	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E4K03_09930	ENOG4105CUX	Signal transduction histidine kinase
E4K03_09955	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
E4K03_09960	ENOG4105KNE	Phosphatidate cytidylyltransferase
E4K03_09970	ENOG4105DZP	Membrane-associated zinc metalloprotease
E4K03_09975	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E4K03_09995	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E4K03_10010	ENOG4105Y3E	Modulates RecA activity (By similarity)
E4K03_10020	ENOG4105VEJ	Heat shock protein
E4K03_10025	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
E4K03_10055	ENOG4105F7P	transcriptional regulator AsnC family
E4K03_10065	ENOG4105C85	amino acid
E4K03_10080	ENOG4105CHH	sulfate transporter
E4K03_10085	ENOG4108RAV	Conserved protein
E4K03_10095	ENOG4105D8V	Glucose sorbosone dehydrogenase
E4K03_10105	ENOG4105BZU	Histidine kinase
E4K03_10125	ENOG4105DM4	PTS System
E4K03_10130	ENOG4105DE4	1-phosphofructokinase
E4K03_10160	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
E4K03_10165	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
E4K03_10170	ENOG4105CC0	LysR family Transcriptional regulator
E4K03_10180	ENOG4105M2J	Glutaredoxin
E4K03_10185	ENOG4105C8Y	Acetylornithine aminotransferase
E4K03_10190	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
E4K03_10220	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
E4K03_10230	ENOG41068P6	UPF0319 protein
E4K03_10250	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
E4K03_10255	ENOG4105C4M	(Ubiquinol oxidase) subunit I
E4K03_10265	ENOG4105PV3	Inner membrane protein yqiJ
E4K03_10280	ENOG4105E0K	tonB-dependent siderophore receptor
E4K03_10290	ENOG4105HDD	phospholipase
E4K03_10295	ENOG4105CZN	Potassium uptake protein
E4K03_10305	ENOG4105C7B	Threonine dehydratase
E4K03_10345	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
E4K03_10350	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E4K03_10360	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
E4K03_10375	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E4K03_10420	ENOG4107VMU	Membrane
E4K03_10425	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
E4K03_10435	ENOG4107QP7	CoA-transferase subunit A
E4K03_10440	ENOG4107QNJ	CoA-transferase subunit B
E4K03_10445	ENOG4105CHU	acetyl-coa acetyltransferase
E4K03_10450	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
E4K03_10455	ENOG4105F2Z	3-oxoadipate enol-lactonase
E4K03_10460	ENOG4105D2S	major facilitator superfamily
E4K03_10465	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
E4K03_10470	ENOG4105EU7	Protocatechuate 3,4-dioxygenase, beta
E4K03_10475	ENOG4105RM9	Protocatechuate 3,4-dioxygenase alpha
E4K03_10480	ENOG4105FF2	Type I DHQase
E4K03_10485	ENOG4106JPM	3-dehydroshikimate dehydratase
E4K03_10490	ENOG4105TW1	Carbohydrate-selective porin OprB
E4K03_10495	ENOG4105DZG	Dehydrogenase
E4K03_10505	ENOG4105MD1	YeeE YedE family protein
E4K03_10520	ENOG4107HP6	Transcriptional regulator
E4K03_10525	ENOG4108PTX	LysR family Transcriptional regulator
E4K03_10530	ENOG4105C1G	acyl-Coa dehydrogenase
E4K03_10555	ENOG4105DNH	Major Facilitator
E4K03_10565	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
E4K03_10585	ENOG4105FUY	alpha subunit
E4K03_10595	ENOG4105CHR	reductase
E4K03_10615	ENOG4105F11	amine oxidase
E4K03_10625	ENOG4105C26	Dehydrogenase
E4K03_10630	ENOG4105F2Z	3-oxoadipate enol-lactonase
E4K03_10635	ENOG4105CHU	acetyl-coa acetyltransferase
E4K03_10640	ENOG4107QNJ	CoA-transferase subunit B
E4K03_10645	ENOG4107QP7	CoA-transferase subunit A
E4K03_10655	ENOG4105NN7	muconolactone delta-isomerase
E4K03_10660	ENOG4105DTQ	mandelate racemase muconate lactonizing
E4K03_10665	ENOG4108KB2	LysR family Transcriptional regulator
E4K03_10675	ENOG4107EJG	GntR family transcriptional regulator
E4K03_10695	ENOG4105CZJ	Aldehyde dehydrogenase
E4K03_10710	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E4K03_10725	ENOG4108Z6Z	Transcriptional regulator
E4K03_10750	ENOG4107Z3H	Transcriptional regulator, TetR family
E4K03_10755	ENOG4108PTX	LysR family Transcriptional regulator
E4K03_10760	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
E4K03_10765	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
E4K03_10795	ENOG4105CSU	acyl-Coa dehydrogenase
E4K03_10825	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
E4K03_10875	ENOG4105ENX	hydrolase
E4K03_10880	ENOG4105EQ2	LysR family Transcriptional regulator
E4K03_10885	ENOG4108BAS	reductase
E4K03_10895	ENOG4108R6W	Transcriptional regulator, ARAC family
E4K03_10900	ENOG4108821	RND type efflux pump
E4K03_10905	ENOG4105E0F	Histidine kinase
E4K03_10910	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E4K03_10915	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
E4K03_10920	ENOG4105BZS	acriflavin resistance protein
E4K03_10945	ENOG4105X0I	Fimbrial
E4K03_10995	ENOG4107RZC	phospholipase d
E4K03_11015	ENOG4108IGT	Dipeptidase
E4K03_11050	ENOG4107T31	5'-nucleotidase
E4K03_11060	ENOG4105WQI	isochorismatase
E4K03_11065	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
E4K03_11070	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
E4K03_11075	ENOG4105E0C	molybdate abc transporter
E4K03_11080	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
E4K03_11085	ENOG4105F4R	Transcriptional regulator mode
E4K03_11090	ENOG4108Q89	anthranilate 1,2-dioxygenase large subunit
E4K03_11095	ENOG4108YS2	small subunit
E4K03_11100	ENOG4105F57	Anthranilate dioxygenase reductase
E4K03_11125	ENOG4105CHR	reductase
E4K03_11135	ENOG4105D2S	major facilitator superfamily
E4K03_11140	ENOG4105CF7	AraC family transcriptional regulator
E4K03_11150	ENOG4105DTD	Dehydrogenase
E4K03_11155	ENOG4105CY2	Citrate transporter
E4K03_11165	ENOG4108M0I	Transcriptional regulator
E4K03_11180	ENOG4105CRW	Short chain fatty acid transporter
E4K03_11185	ENOG4105CHU	acetyl-coa acetyltransferase
E4K03_11200	ENOG4107YNJ	LysR family Transcriptional regulator
E4K03_11215	ENOG4108IJ0	Aspartate ammonia-lyase
E4K03_11225	ENOG4105CSH	Transporter
E4K03_11245	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
E4K03_11250	ENOG4106FTQ	Taurine ABC transporter, periplasmic
E4K03_11260	ENOG4105CBX	hi0933 family
E4K03_11265	ENOG4105FDP	GntR family transcriptional regulator
E4K03_11275	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
E4K03_11280	ENOG4105KVH	Transcriptional regulator
E4K03_11285	ENOG4105UEI	Transcriptional Regulator AraC Family
E4K03_11300	ENOG4108VCT	Sulfite exporter TauE/SafE
E4K03_11310	ENOG4107QPB	Beta-lactamase domain protein
E4K03_11320	ENOG4105FFC	UPF0187 protein
E4K03_11330	ENOG4105CHR	reductase
E4K03_11345	ENOG4105CPP	Dehydrogenase, E1 component
E4K03_11350	ENOG4107R0V	Pyruvate dehydrogenase
E4K03_11355	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
E4K03_11370	ENOG4105BZU	Histidine kinase
E4K03_11380	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
E4K03_11385	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
E4K03_11430	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
E4K03_11445	ENOG4105C28	cystathionine
E4K03_11455	ENOG4105F2W	methyltransferase
E4K03_11490	ENOG4105K59	histidine triad (HIT) protein
E4K03_11515	ENOG4107QWP	ABC-2 type transporter
E4K03_11520	ENOG4107QWP	ABC-2 type transporter
E4K03_11525	ENOG4105CJ1	ABC, transporter
E4K03_11540	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E4K03_11555	ENOG4105CNM	Receptor
E4K03_11575	ENOG4107TSN	permease
E4K03_11580	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
E4K03_11600	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
E4K03_11605	ENOG4108YZT	Adenosylcobinamide kinase
E4K03_11650	ENOG4105JSC	dimethylmenaquinone methyltransferase
E4K03_11660	ENOG4105DJU	Siderophore biosynthesis protein
E4K03_11665	ENOG4105DUU	IucA IucC family protein
E4K03_11685	ENOG4108Z66	YbaK ebsC protein
E4K03_11700	ENOG4105C1G	acyl-Coa dehydrogenase
E4K03_11705	ENOG4105C1G	acyl-Coa dehydrogenase
E4K03_11710	ENOG4105EEF	Alkane 1-monooxygenase
E4K03_11715	ENOG4105E7U	AraC family transcriptional regulator
E4K03_11720	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
E4K03_11725	ENOG4105K70	DNA-binding protein
E4K03_11740	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
E4K03_11750	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
E4K03_11755	ENOG4108Z4V	iron-sulfur cluster assembly
E4K03_11770	ENOG4108ZIT	Ferredoxin, 2FE-2S
E4K03_11775	ENOG4105F8J	Adenylate Guanylate cyclase
E4K03_11785	ENOG4108JA2	transcriptioN-repair coupling factor
E4K03_11805	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
E4K03_11810	ENOG4105K4T	epimerase
E4K03_11825	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
E4K03_11845	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E4K03_11855	ENOG4105DGW	oligopeptidase A
E4K03_11875	ENOG4108DNJ	Pfam:TonB
E4K03_11890	ENOG4105SG9	biopolymer transport protein, ExbD
E4K03_11900	ENOG4107QP3	malate synthase g
E4K03_11905	ENOG4105D6Z	AFG1 family ATPase
E4K03_11915	ENOG4107RN6	Monooxygenase
E4K03_11935	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
E4K03_11940	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
E4K03_11955	ENOG4108Z6B	deaminase
E4K03_11975	ENOG4108RTD	type II secretion system protein K
E4K03_12000	ENOG4105F8V	Hydrolase, tatD family
E4K03_12010	ENOG4107QRG	dna polymerase iii
E4K03_12020	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
E4K03_12025	ENOG4105BZ1	(ABC) transporter
E4K03_12040	ENOG4105FA0	parb-like partition protein
E4K03_12045	ENOG4107QJE	Chromosome Partitioning Protein
E4K03_12055	ENOG4108S0S	Nucleotidyl transferase
E4K03_12060	ENOG4105EHM	Aminoglycoside phosphotransferase
E4K03_12065	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
E4K03_12070	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
E4K03_12075	ENOG4105D2N	Aldolase
E4K03_12095	ENOG4108UHJ	MAF-like protein
E4K03_12100	ENOG4105EZE	Cupin 4 family protein
E4K03_12125	ENOG4105XPP	Protein of unknown function (DUF1275)
E4K03_12130	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
E4K03_12135	ENOG4105BZ1	(ABC) transporter
E4K03_12145	ENOG4108ZX5	transcriptional regulator
E4K03_12155	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
E4K03_12160	ENOG4105CK7	Sodium proline symporter
E4K03_12165	ENOG4105EW9	transcriptional regulator AsnC family
E4K03_12170	ENOG4105C26	Dehydrogenase
E4K03_12175	ENOG4105YGK	Pfam:UPF0157
E4K03_12190	ENOG4108T58	Mg2 transport protein CorA
E4K03_12200	ENOG4108YYC	ycei family
E4K03_12210	ENOG4105CV1	Transketolase (EC 2.2.1.1)
E4K03_12235	ENOG4108HWY	Beta-lactamase
E4K03_12255	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
E4K03_12260	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
E4K03_12280	ENOG4105X0I	Fimbrial
E4K03_12285	ENOG4105GQR	Chaperone
E4K03_12325	ENOG4108IPJ	Membrane
E4K03_12335	ENOG4105ETS	cytosine purines uracil thiamine allantoin
E4K03_12345	ENOG4105CC0	LysR family Transcriptional regulator
E4K03_12395	ENOG41067SE	Tetr family transcriptional regulator
E4K03_12410	ENOG4105EW9	transcriptional regulator AsnC family
E4K03_12420	ENOG4105CDA	abc transporter atp-binding protein
E4K03_12425	ENOG4105DRP	amino acid AbC transporter
E4K03_12430	ENOG4105EAD	ABC transporter
E4K03_12445	ENOG4107T8P	acyl-Coa dehydrogenase
E4K03_12460	ENOG4105D01	(LipO)protein
E4K03_12465	ENOG4105D01	(LipO)protein
E4K03_12470	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
E4K03_12475	ENOG4108UMI	ABC transporter, permease
E4K03_12480	ENOG4105C3G	gtp-binding protein
E4K03_12505	ENOG4108UMN	azlc family
E4K03_12510	ENOG4105ZED	uncharacterized protein ygaH
E4K03_12540	ENOG4105E7U	AraC family transcriptional regulator
E4K03_12545	ENOG4108V06	Glutathione peroxidase
E4K03_12555	ENOG4105CHM	Aminotransferase
E4K03_12575	ENOG4105C0B	DNA polymerase III (alpha subunit)
E4K03_12605	ENOG4108JU3	Alkyl hydroperoxide reductase
E4K03_12620	ENOG4108KB2	LysR family Transcriptional regulator
E4K03_12625	ENOG4105D6J	arsenicaL-resistance protein
E4K03_12630	ENOG41082YX	Transcriptional regulator, arsr family
E4K03_12645	ENOG4105CPN	adenine deaminase
E4K03_12655	ENOG4105CBN	LysR family transcriptional regulator
E4K03_12665	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
E4K03_12675	ENOG4105E2B	Taurine dioxygenase
E4K03_12680	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
E4K03_12685	ENOG4108IY8	ABC, transporter
E4K03_12690	ENOG4106FTQ	Taurine ABC transporter, periplasmic
E4K03_12700	ENOG4105C54	Major Facilitator superfamily
E4K03_12725	ENOG4105C4M	(Ubiquinol oxidase) subunit I
E4K03_12730	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
E4K03_12740	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
E4K03_12745	ENOG4108K70	Transcriptional regulator
E4K03_12760	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
E4K03_12765	ENOG4105PSI	phosphoribosyl-dephospho-CoA transferase
E4K03_12780	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
E4K03_12785	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
E4K03_12795	ENOG4105ETT	transcriptional Regulator, LysR family
E4K03_12805	ENOG4105DXI	Major Facilitator superfamily
E4K03_12825	ENOG41067MG	lrgb family
E4K03_12830	ENOG4105VAW	lrga family
E4K03_12835	ENOG4105CMU	LysR family (Transcriptional regulator
E4K03_12840	ENOG4108SHQ	Glutathione S-transferase
E4K03_12845	ENOG4105CYM	Glutathione S-transferase
E4K03_12850	ENOG4105CBN	LysR family transcriptional regulator
E4K03_12855	ENOG4105CHR	reductase
E4K03_12865	ENOG4105D7W	serine acetyltransferase
E4K03_12870	ENOG4105ESN	nucleotide-binding protein
E4K03_12875	ENOG4105C9B	Cysteine desulfurase
E4K03_12885	ENOG4105EXG	Transcriptional regulator
E4K03_12895	ENOG4105CT1	(ABC) transporter
E4K03_12900	ENOG4107RP9	extracellular solute-binding protein, family 3
E4K03_12910	ENOG4108HW4	amino acid AbC transporter
E4K03_12915	ENOG4105EAD	ABC transporter
E4K03_12930	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E4K03_12935	ENOG4105BZU	Histidine kinase
E4K03_12945	ENOG4105EW9	transcriptional regulator AsnC family
E4K03_12955	ENOG4105KT5	UmuD protein
E4K03_12980	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
E4K03_13040	ENOG4105HEI	LysR family (Transcriptional regulator
E4K03_13075	ENOG4105CEY	Amp-dependent synthetase and ligase
E4K03_13080	ENOG4105R8C	Transcriptional regulator
E4K03_13085	ENOG4105C1G	acyl-Coa dehydrogenase
E4K03_13090	ENOG4107QX3	carboxylase
E4K03_13095	ENOG4105E39	Enoyl-CoA hydratase
E4K03_13110	ENOG4105CC0	LysR family Transcriptional regulator
E4K03_13125	ENOG4105CSU	acyl-Coa dehydrogenase
E4K03_13135	ENOG4105EQ0	Major Facilitator superfamily
E4K03_13145	ENOG4107QNJ	CoA-transferase subunit B
E4K03_13150	ENOG4107QP7	CoA-transferase subunit A
E4K03_13155	ENOG4107RGD	Major Facilitator superfamily
E4K03_13160	ENOG4105C1G	acyl-Coa dehydrogenase
E4K03_13165	ENOG4105E39	Enoyl-CoA hydratase
E4K03_13170	ENOG4105CHR	reductase
E4K03_13175	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E4K03_13180	ENOG4105CHU	acetyl-coa acetyltransferase
E4K03_13190	ENOG4105EQ0	Major Facilitator superfamily
E4K03_13195	ENOG4105EA8	2-Nitropropane dioxygenase
E4K03_13200	ENOG4108UKI	Enoyl-CoA hydratase
E4K03_13215	ENOG4105C1G	acyl-Coa dehydrogenase
E4K03_13220	ENOG4107RGD	Major Facilitator superfamily
E4K03_13225	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
E4K03_13230	ENOG4107STF	Involved in phosphonate degradation (By similarity)
E4K03_13240	ENOG4107RCV	ABC transporter, permease
E4K03_13245	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E4K03_13250	ENOG4105C4Y	ABC transporter
E4K03_13265	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
E4K03_13270	ENOG4107HP6	Transcriptional regulator
E4K03_13280	ENOG4105HEI	LysR family (Transcriptional regulator
E4K03_13285	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
E4K03_13290	ENOG4105C26	Dehydrogenase
E4K03_13300	ENOG4105ETS	cytosine purines uracil thiamine allantoin
E4K03_13310	ENOG4105C26	Dehydrogenase
E4K03_13315	ENOG4108M8W	Monooxygenase
E4K03_13320	ENOG4105MXW	flavin reductase domain protein, FMN-binding
E4K03_13325	ENOG4108MXF	Alpha Beta Hydrolase
E4K03_13350	ENOG4105CPW	cytochrome b561
E4K03_13355	ENOG4107VGR	Catalase
E4K03_13390	ENOG4107YAU	phenylacetic acid degradation protein
E4K03_13395	ENOG4108Z0R	Transferase
E4K03_13400	ENOG4105V9J	phenylacetic acid degradation operon negative regulatory protein
E4K03_13405	ENOG4105DZS	Phenylacetate-CoA ligase
E4K03_13410	ENOG4105CHU	acetyl-coa acetyltransferase
E4K03_13415	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E4K03_13420	ENOG4108UKI	Enoyl-CoA hydratase
E4K03_13425	ENOG4105E39	Enoyl-CoA hydratase
E4K03_13430	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
E4K03_13435	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
E4K03_13440	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
E4K03_13445	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
E4K03_13450	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
E4K03_13455	ENOG4105DXM	phenylacetic acid degradation protein
E4K03_13460	ENOG4105EJQ	L-serine dehydratase
E4K03_13465	ENOG4107QTZ	amino acid
E4K03_13470	ENOG4105CZJ	Aldehyde dehydrogenase
E4K03_13505	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
E4K03_13525	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E4K03_13540	ENOG4108Z4X	TRANSCRIPTIONal
E4K03_13550	ENOG4105WPN	DNA integration recombination invertion protein
E4K03_13570	ENOG4107Y2X	deaminase
E4K03_13580	ENOG4105EMY	transcriptional regulator
E4K03_13625	ENOG4105MRR	Transcriptional regulator (By similarity)
E4K03_13640	ENOG4108MXQ	glutathione-regulated potassium-efflux system ancillary protein KefF
E4K03_13645	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
E4K03_13660	ENOG4105E2A	Dehydrogenase
E4K03_13670	ENOG4105R8C	Transcriptional regulator
E4K03_13685	ENOG4107R4J	Chloride channel
E4K03_13690	ENOG4108JIK	carboxylase
E4K03_13710	ENOG4105C5A	transporter
E4K03_13715	ENOG4108WAV	Transcriptional regulator
E4K03_13745	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
E4K03_13765	ENOG4105D2S	major facilitator superfamily
E4K03_13780	ENOG4105D1S	lipid A biosynthesis
E4K03_13785	ENOG4105BZU	Histidine kinase
E4K03_13790	ENOG4107AQZ	Membrane
E4K03_13810	ENOG4108Z4U	Ferredoxin
E4K03_13850	ENOG4105DFG	type I secretion outer membrane protein
E4K03_13855	ENOG4108IUZ	ABC transporter
E4K03_13860	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
E4K03_13870	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
E4K03_13875	ENOG4105C2X	Arabinose 5-phosphate isomerase
E4K03_13910	ENOG4107YPT	transcriptional regulator
E4K03_13950	ENOG4105II7	pyrroline-5-carboxylate reductase
E4K03_13960	ENOG4105VEQ	Cold shock protein
E4K03_13965	ENOG410829K	Lysine exporter protein (Lyse ygga)
E4K03_14000	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
E4K03_14055	ENOG4108KB2	LysR family Transcriptional regulator
E4K03_14060	ENOG4105FUY	alpha subunit
E4K03_14065	ENOG4108UKV	benzoate 1,2-dioxygenase
E4K03_14070	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
E4K03_14075	ENOG4107SEV	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
E4K03_14080	ENOG4105DKK	Benzoate
E4K03_14085	ENOG4105D2S	major facilitator superfamily
E4K03_14100	ENOG4105CQ7	ATP-dependent helicase
E4K03_14105	ENOG4105D3R	alkyl hydroperoxide reductase
E4K03_14115	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
E4K03_14125	ENOG4108JU3	Alkyl hydroperoxide reductase
E4K03_14135	ENOG4108K3A	Glutathione S-transferase
E4K03_14145	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
E4K03_14150	ENOG4108TGY	Glutathione S-transferase
E4K03_14160	ENOG4108ZG0	Ompa motb domain protein
E4K03_14165	ENOG4105CD3	dihydroorotase
E4K03_14195	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E4K03_14220	ENOG4108UKZ	OsmC family
E4K03_14225	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
E4K03_14230	ENOG4105CPC	Aldo Keto reductase
E4K03_14245	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
E4K03_14260	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
E4K03_14270	ENOG4105CFH	Aspartokinase
E4K03_14280	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
E4K03_14290	ENOG4105CPW	cytochrome b561
E4K03_14310	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
E4K03_14315	ENOG4105C7N	Xanthine uracil vitamin C permease
E4K03_14325	ENOG4105F95	Monooxygenase
E4K03_14360	ENOG4105F95	Monooxygenase
E4K03_14365	ENOG4105JQZ	Methyltransferase
E4K03_14375	ENOG4107RN6	Monooxygenase
E4K03_14395	ENOG4105EPF	Outer membrane porin
E4K03_14400	ENOG4105D2S	major facilitator superfamily
E4K03_14410	ENOG4105E3J	oxidoreductase
E4K03_14425	ENOG4108SC4	)-transporter
E4K03_14430	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
E4K03_14445	ENOG4105C1G	acyl-Coa dehydrogenase
E4K03_14465	ENOG4105C85	amino acid
E4K03_14475	ENOG4107Y60	(LipO)protein
E4K03_14485	ENOG4106B0W	Curli production assembly transport component CsgG
E4K03_14515	ENOG4105D01	(LipO)protein
E4K03_14525	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E4K03_14545	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
E4K03_14565	ENOG4108JQ5	ABC transporter
E4K03_14570	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
E4K03_14575	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
E4K03_14585	ENOG4105E9H	Lytic Murein transglycosylase
E4K03_14585	ENOG4105E9H	Lytic Murein transglycosylase
E4K03_14590	ENOG4107RZZ	dna polymerase iii epsilon subunit
E4K03_14610	ENOG4105E09	nadh pyrophosphatase
E4K03_14620	ENOG4105W4M	Transport-associated protein
E4K03_14635	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
E4K03_14645	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
E4K03_14650	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
E4K03_14670	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
E4K03_14675	ENOG4105D0A	hydroxylase
E4K03_14680	ENOG4107RAQ	aminopeptidase
E4K03_14710	ENOG4105DIJ	Phosphoethanolamine transferase
E4K03_14795	ENOG4105UPP	uncharacterized protein ydcA
E4K03_15095	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
E4K03_15130	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
E4K03_15140	ENOG4105D82	Glutamate dehydrogenase
E4K03_15145	ENOG4108R3D	Electron transport complex
E4K03_15150	ENOG4105CSM	endonuclease III
E4K03_15175	ENOG4105CJN	penicillin-binding protein
E4K03_15180	ENOG4106H78	methyltransferase
E4K03_15195	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
E4K03_15205	ENOG4105CQM	Urea amidohydrolase subunit alpha
E4K03_15235	ENOG4107RET	Isocitrate lyase
E4K03_15245	ENOG4105C37	(CBS) domain
E4K03_15255	ENOG4105D4T	Citrate transporter
E4K03_15270	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
E4K03_15285	ENOG4108MRJ	
E4K03_15305	ENOG4105VCQ	rubredoxin
E4K03_15310	ENOG4107QZF	nitrite reductase NADPH large subunit
E4K03_15320	ENOG4105C5Q	Transcriptional regulator
E4K03_15345	ENOG4107U91	Rhomboid family
E4K03_15350	ENOG4105CV6	ABC transporter, permease
E4K03_15355	ENOG4108I0Y	(ABC) transporter
E4K03_15360	ENOG4108UJV	acyl-CoA thioesterase i
E4K03_15380	ENOG4107RNH	Outer membrane receptor FepA
E4K03_15395	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
E4K03_15400	ENOG4105E6M	Sulphatase-modifying factor protein
E4K03_15420	ENOG4105CJ3	phosphate transporter
E4K03_15425	ENOG4105C3R	Methionine synthase
E4K03_15440	ENOG4105CSP	Major Facilitator Superfamily
E4K03_15450	ENOG4108PZW	LysR family Transcriptional regulator
E4K03_15465	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
E4K03_15475	ENOG4105EU0	Major facilitator Superfamily
E4K03_15480	ENOG4108R6W	Transcriptional regulator, ARAC family
E4K03_15485	ENOG4105CSV	Glutaminase
E4K03_15490	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
E4K03_15495	ENOG4105CSH	Transporter
E4K03_15505	ENOG4105C7K	acetolactate synthase
E4K03_15520	ENOG4105CHR	reductase
E4K03_15525	ENOG4108MXF	Alpha Beta Hydrolase
E4K03_15535	ENOG4105DJB	Major Facilitator Superfamily
E4K03_15540	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
E4K03_15550	ENOG4105CHR	reductase
E4K03_15570	ENOG41069M3	Transcriptional regulator
E4K03_15585	ENOG4106YT9	Enoyl-CoA hydratase
E4K03_15595	ENOG4105CND	Glycosyl transferase, family 2
E4K03_15600	ENOG4107BJW	polysaccharide deacetylase
E4K03_15610	ENOG4108VWS	Yaeq family
E4K03_15620	ENOG4105CKI	cobalamin synthesis protein
E4K03_15640	ENOG4105C94	Transporter
E4K03_15645	ENOG4105C94	Transporter
E4K03_15650	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
E4K03_15675	ENOG4107QK5	Homocysteine s-methyltransferase
E4K03_15680	ENOG4105D5Q	Arginine ornithine antiporter
E4K03_15705	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E4K03_15710	ENOG4105C54	Major Facilitator superfamily
E4K03_15750	ENOG4107R3N	Filamentation induced by cAMP protein fic
E4K03_15755	ENOG4108UUM	single-stranded DNA-binding protein
E4K03_15800	ENOG4105DFP	Integrase
E4K03_15810	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
E4K03_15815	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
E4K03_15820	ENOG4105CW7	secretion protein, HlyD family
E4K03_15825	ENOG4108VUY	thioesterase Superfamily protein
E4K03_15830	ENOG4105D52	delta-aminolevulinic acid dehydratase
E4K03_15835	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
E4K03_15840	ENOG4105ECP	epimerase
E4K03_15860	ENOG4107RH8	nuclease SbcCD subunit D
E4K03_15865	ENOG4105EYH	Exonuclease
E4K03_15870	ENOG4105DFA	alanine racemase domain protein
E4K03_15875	ENOG4105CZX	twitching motility protein
E4K03_15880	ENOG4105CZX	twitching motility protein
E4K03_15885	ENOG41090R7	Ferric uptake
E4K03_15915	ENOG4105E7A	Glutamine amidotransferase
E4K03_15930	ENOG4107QKV	phosphomannomutase
E4K03_15940	ENOG4105C4R	Atp-dependent dna helicase
E4K03_15945	ENOG4108ZG0	Ompa motb domain protein
E4K03_15950	ENOG4106HNH	Acyl-transferase
E4K03_15965	ENOG4107QMS	site-determining protein
E4K03_15985	ENOG4105CNU	cell division protein FtsK
E4K03_15990	ENOG4105C3M	thioredoxin reductase
E4K03_15995	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
E4K03_16005	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
E4K03_16050	ENOG4108YXA	Membrane
E4K03_16055	ENOG4105EUB	pirin domain protein
E4K03_16065	ENOG4105C4K	Nad synthetase
E4K03_16080	ENOG4105E3J	oxidoreductase
E4K03_16085	ENOG4105C26	Dehydrogenase
E4K03_16090	ENOG4105DVW	rieske (2Fe-2S)
E4K03_16100	ENOG4105C94	Transporter
E4K03_16105	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
E4K03_16110	ENOG4105EJC	lysr family transcriptional regulator
E4K03_16130	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
E4K03_16150	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
E4K03_16155	ENOG4105C34	Pseudouridine synthase
E4K03_16160	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E4K03_16165	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
E4K03_16180	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
E4K03_16210	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
E4K03_16240	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
E4K03_16250	ENOG4105DWF	phosphomethylpyrimidine kinase
E4K03_16255	ENOG4109066	lysm domain bon superfamily protein
E4K03_16265	ENOG4105CHR	reductase
E4K03_16270	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
E4K03_16280	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
E4K03_16285	ENOG4108BPE	-transporting atpase
E4K03_16290	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
E4K03_16295	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
E4K03_16300	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
E4K03_16305	ENOG4105FE9	pseudouridine synthase
E4K03_16315	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
E4K03_16320	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
E4K03_16330	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
E4K03_16335	ENOG4108K4C	ec 3.1.3.12
E4K03_16340	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
E4K03_16345	ENOG4106UW1	Major Facilitator superfamily
E4K03_16365	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
E4K03_16375	ENOG4105HF0	Membrane
E4K03_16390	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E4K03_16400	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
E4K03_16460	ENOG4105D1F	ATP-binding protein
E4K03_16470	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
E4K03_16500	ENOG4105K6H	D-cysteine desulfhydrase
E4K03_16505	ENOG4105CBX	hi0933 family
E4K03_16530	ENOG4105DP0	ferredoxin-NADP reductase
E4K03_16535	ENOG4105DUM	transcriptional regulator, lysR family
E4K03_16555	ENOG4105C8S	subunit m
E4K03_16560	ENOG4105D65	subunit l
E4K03_16570	ENOG4107UFS	subunit j
E4K03_16585	ENOG4108IEH	NADH dehydrogenase subunit g
E4K03_16590	ENOG4107QIZ	NADH dehydrogenase
E4K03_16595	ENOG4105GKE	subunit e
E4K03_16615	ENOG4105BZU	Histidine kinase
E4K03_16625	ENOG4105E0F	Histidine kinase
E4K03_16630	ENOG4107EXC	regulatoR
E4K03_16640	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E4K03_16650	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E4K03_16670	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
E4K03_16675	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
E4K03_16685	ENOG4105ETT	transcriptional Regulator, LysR family
E4K03_16695	ENOG4106P55	Transcriptional regulator
E4K03_16715	ENOG4106P55	Transcriptional regulator
E4K03_16720	ENOG4107EFR	Flavocytochrome c
E4K03_16740	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
E4K03_16745	ENOG4107RGD	Major Facilitator superfamily
E4K03_16750	ENOG4105C1G	acyl-Coa dehydrogenase
E4K03_16755	ENOG4105ETT	transcriptional Regulator, LysR family
E4K03_16790	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
E4K03_16795	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
E4K03_16800	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
E4K03_16815	ENOG4105VR0	copper resistance
E4K03_16820	ENOG4105E3B	Multicopper oxidase
E4K03_16830	ENOG4108HCJ	Hydrolase
E4K03_16835	ENOG4105DJV	ribulose-phosphate 3-epimerase
E4K03_16845	ENOG4105C4W	S-formylglutathione hydrolase
E4K03_16860	ENOG41072GX	Peptidase M22 Glycoprotease
E4K03_16865	ENOG4108Z0R	Transferase
E4K03_16880	ENOG4105D5G	Transposase
E4K03_16895	ENOG4105CRQ	synthase (Component I)
E4K03_16905	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
E4K03_16910	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
E4K03_16915	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
E4K03_16985	ENOG4105K56	Transcriptional regulator
E4K03_16990	ENOG4108ZHJ	Organic hydroperoxide resistance protein
E4K03_16995	ENOG4107QHF	type ii secretion system protein e
E4K03_17015	ENOG4105C2M	dna polymerase I
E4K03_17020	ENOG4108VIA	integral membrane protein
E4K03_17025	ENOG4105II7	pyrroline-5-carboxylate reductase
E4K03_17030	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
E4K03_17040	ENOG4105C9X	ppx gppa phosphatase
E4K03_17050	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
E4K03_17070	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
E4K03_17095	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
E4K03_17110	ENOG4105W39	Membrane
E4K03_17115	ENOG4105CYM	Glutathione S-transferase
E4K03_17130	ENOG4105CEY	Amp-dependent synthetase and ligase
E4K03_17135	ENOG4105N42	UPF0307 protein
E4K03_17140	ENOG41080Z8	PHOSPHOCARRIER protein
E4K03_17160	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E4K03_17165	ENOG4105DJ0	Poly(A) Polymerase
E4K03_17170	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
E4K03_17175	ENOG4105DXN	mazG family
E4K03_17185	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E4K03_17200	ENOG4105C6T	cysteine synthase
E4K03_17205	ENOG4105BZU	Histidine kinase
E4K03_17210	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
E4K03_17215	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
E4K03_17220	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
E4K03_17235	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
E4K03_17240	ENOG4105W8H	transhydrogenase (subunit alpha
E4K03_17245	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
E4K03_17250	ENOG4106UX7	integral membrane protein
E4K03_17265	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
E4K03_17275	ENOG4107RSM	transcriptional regulator
E4K03_17285	ENOG4105CUZ	uba thif-type nad fad binding protein
E4K03_17290	ENOG4107QM5	aconitate hydratase
E4K03_17295	ENOG4105F8V	Hydrolase, tatD family
E4K03_17310	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
E4K03_17335	ENOG4105BZU	Histidine kinase
E4K03_17345	ENOG4108ZP8	Acetolactate synthase small subunit
E4K03_17350	ENOG4105C7K	acetolactate synthase
E4K03_17375	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
E4K03_17380	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E4K03_17385	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E4K03_17390	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
E4K03_17400	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
E4K03_17405	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
E4K03_17415	ENOG4105VW4	glutaredoxin 3
E4K03_17435	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
E4K03_17455	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
E4K03_17475	ENOG4105WVQ	Fe-S assembly protein IscX
E4K03_17490	ENOG4105CN1	protease
E4K03_17505	ENOG4106HB6	Alpha beta hydrolase
E4K03_17515	ENOG4105C26	Dehydrogenase
E4K03_17520	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
E4K03_17525	ENOG4105C6Z	Gluconate
E4K03_17530	ENOG4108UHU	Aldolase
E4K03_17535	ENOG4105C01	Dihydroxy-acid dehydratase
E4K03_17540	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
E4K03_17545	ENOG4108DNC	Involved in acetate metabolism (By similarity)
E4K03_17550	ENOG4107GFK	fumarate
E4K03_17570	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
E4K03_17580	ENOG4108ESX	Receptor
E4K03_17590	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
E4K03_17600	ENOG4105DWV	Homoserine O-trans-acetylase
E4K03_17700	ENOG4105CIY	formyltetrahydrofolate deformylase
E4K03_17710	ENOG4107RGH	Aldehyde dehydrogenase
E4K03_17715	ENOG4105KDC	50s ribosomal protein l28
E4K03_17720	ENOG4105W0E	50S ribosomal protein L33
E4K03_17725	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
E4K03_17745	ENOG4105VFU	Rna-binding protein
E4K03_17750	ENOG4105C4R	Atp-dependent dna helicase
E4K03_17765	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
E4K03_17775	ENOG4105KVH	Transcriptional regulator
E4K03_17785	ENOG41069P5	Protein slyX homolog
E4K03_17790	ENOG4105C5H	ABC transporter
E4K03_17795	ENOG4105N14	lysine exporter protein LysE YggA
E4K03_17800	ENOG4105D1S	lipid A biosynthesis
E4K03_17810	ENOG4105CK2	sodium dicarboxylate symporter
E4K03_17865	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
E4K03_17890	ENOG4105DUM	transcriptional regulator, lysR family
E4K03_17905	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
E4K03_17920	ENOG4108W5M	transcriptional regulator
E4K03_17935	ENOG4105D29	Helix-turn-helix type 11 domain protein
E4K03_17940	ENOG4107XGZ	Hydrolase
E4K03_17945	ENOG4105EI2	Pseudouridine synthase
E4K03_17955	ENOG4105C03	ribonuclease
E4K03_17975	ENOG4105CBN	LysR family transcriptional regulator
E4K03_17980	ENOG4105EMU	Dehydrogenase
E4K03_17985	ENOG4105CSA	Coproporphyrinogen iii oxidase
E4K03_17995	ENOG4107QI1	Mate efflux family protein
E4K03_18005	ENOG4107T8P	acyl-Coa dehydrogenase
E4K03_18040	ENOG4105BZ8	glutamate synthase
E4K03_18050	ENOG4108BEW	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
E4K03_18055	ENOG4105C5X	domain protein
E4K03_18070	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
E4K03_18080	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
E4K03_18085	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
E4K03_18090	ENOG4108JU5	Magnesium and cobalt efflux protein
E4K03_18095	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
E4K03_18100	ENOG4108Z7R	Chaperone CsaA
E4K03_18110	ENOG4108VAU	general secretion pathway protein G
E4K03_18115	ENOG4105D7Q	type ii secretion system
E4K03_18145	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
E4K03_18165	ENOG4105D0M	Protease HtpX homolog
E4K03_18170	ENOG4105BZU	Histidine kinase
E4K03_18220	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E4K03_18225	ENOG4105VN1	Heat shock protein
E4K03_18245	ENOG4105D5G	Transposase
E4K03_18260	ENOG4107QJE	Chromosome Partitioning Protein
E4K03_18265	ENOG4105FA0	parb-like partition protein
E4K03_18270	ENOG4105G6Z	alkaline phosphatase
E4K03_18305	ENOG4105E4P	ATPase (AAA
E4K03_18400	ENOG4108IJF	Heavy metal efflux pump, CzcA
E4K03_18490	ENOG4105MZU	cell filamentation protein
E4K03_18520	ENOG4105E4P	ATPase (AAA
E4K03_18525	ENOG4105R48	this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase
E4K03_18545	ENOG4105DZC	cytosine deaminase
E4K03_18555	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
E4K03_18590	ENOG4105R48	this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase
E4K03_18645	ENOG4105XUP	Phage derived protein Gp49-like (DUF891)
E4K03_18670	ENOG4105VUH	addiction module killer protein
E4K03_18675	ENOG4105YES	addiction module antidote protein
E4K03_18700	ENOG4105YES	addiction module antidote protein
E4K03_18715	ENOG4105C4W	S-formylglutathione hydrolase
E4K03_18730	ENOG4108I6A	alcohol dehydrogenase
E4K03_18745	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E4K03_18755	ENOG4108WUH	Transcriptional regulator, TetR family
E4K03_18760	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
E4K03_18770	ENOG41066UD	Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium
E4K03_18965	ENOG4105D5G	Transposase
E4K03_19000	ENOG4105K5T	PilT protein
E4K03_19035	ENOG4105T95	Thiol disulfide interChange protein
E4K03_19115	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
E4K03_19195	ENOG4105KK6	nuclease
E4K03_19200	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
E4K03_19250	ENOG4105FA0	parb-like partition protein
E4K03_19255	ENOG4105C10	Electron transfer flavoprotein
E4K03_19260	ENOG4107J0C	type IIi
E4K03_19275	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
E4K03_19280	ENOG4105K4U	addiction module toxin, RelE StbE family
E4K03_19330	ENOG4105DIJ	Phosphoethanolamine transferase
E4K03_19355	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
E4K03_19395	ENOG4105E39	Enoyl-CoA hydratase
E4K03_19400	ENOG4105CHU	acetyl-coa acetyltransferase
E4K03_19405	ENOG4105CEY	Amp-dependent synthetase and ligase
E4K03_19415	ENOG4105C1G	acyl-Coa dehydrogenase
E4K03_19440	ENOG4105D2S	major facilitator superfamily
E4K03_19445	ENOG4105CSU	acyl-Coa dehydrogenase
E4K03_19450	ENOG4108Z7G	MaoC domain protein dehydratase
E4K03_19455	ENOG4105BZJ	Electron transfer flavoprotein