locus-tag	class	description
JCR16_00020	COG0592	DNA-directed DNA polymerase activity
JCR16_00030	COG0187	DNA topoisomerase II activity
JCR16_00040	COG0586	Pfam SNARE associated Golgi protein
JCR16_00045	COG0488	(ABC) transporter
JCR16_00070	COG0596	Alpha beta hydrolase
JCR16_00075	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
JCR16_00080	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JCR16_00170	COG2233	PERMEase
JCR16_00185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JCR16_00220	COG2814	Major facilitator Superfamily
JCR16_00225	COG0656	L-ascorbic acid biosynthetic process
JCR16_00230	COG0583	DNA-binding transcription factor activity
JCR16_00245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JCR16_00250	COG1064	alcohol dehydrogenase
JCR16_00255	COG2818	Glycosylase
JCR16_00270	COG1194	a g-specific adenine glycosylase
JCR16_00290	COG2983	Belongs to the UPF0260 family
JCR16_00295	COG2133	pyrroloquinoline quinone binding
JCR16_00300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JCR16_00305	COG2116	formate transmembrane transporter activity
JCR16_00325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JCR16_00330	COG1335	isochorismatase
JCR16_00335	COG0385	Bile acid
JCR16_00340	COG0534	Mate efflux family protein
JCR16_00345	COG1683	Conserved Protein
JCR16_00365	COG0625	glutathione transferase activity
JCR16_00375	COG1113	amino acid transport
JCR16_00385	COG0523	cobalamin synthesis protein
JCR16_00395	COG2188	Transcriptional regulator
JCR16_00425	COG0010	Belongs to the arginase family
JCR16_00440	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JCR16_00445	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JCR16_00455	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JCR16_00460	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JCR16_00560	COG0534	Mate efflux family protein
JCR16_00565	COG0436	Aminotransferase
JCR16_00570	COG2733	membrane
JCR16_00585	COG2918	glutathione biosynthetic process
JCR16_00600	COG0791	NLP P60 protein
JCR16_00600	COG1388	LysM domain
JCR16_00615	COG3150	esterase
JCR16_00625	COG1028	Short-chain dehydrogenase reductase Sdr
JCR16_00630	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
JCR16_00640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JCR16_00650	COG2233	PERMEase
JCR16_00655	COG2351	hydroxyisourate hydrolase activity
JCR16_00690	COG3706	GGDEF domain
JCR16_00705	COG1393	Belongs to the ArsC family
JCR16_00710	COG0708	Exodeoxyribonuclease III
JCR16_00730	COG0189	ligase activity
JCR16_00750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JCR16_00760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JCR16_00775	COG4942	peptidase
JCR16_00785	COG0508	dehydrogenase complex catalyzes the overall conversion of
JCR16_00795	COG2119	membrane
JCR16_00800	COG4774	siderophore transport
JCR16_00805	COG0426	domain, Protein
JCR16_00805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JCR16_00830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JCR16_00850	COG1902	pentaerythritol trinitrate reductase activity
JCR16_00855	COG1519	Transferase
JCR16_00860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JCR16_00865	COG0668	transmembrane transport
JCR16_00875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JCR16_00880	COG1335	isochorismatase
JCR16_00885	COG1522	sequence-specific DNA binding
JCR16_00890	COG3328	transposase activity
JCR16_00915	COG2198	Histidine kinase
JCR16_00915	COG0784	Response regulator, receiver
JCR16_00915	COG2205	protein histidine kinase activity
JCR16_00920	COG3162	membrane
JCR16_00925	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JCR16_00935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JCR16_00955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JCR16_00960	COG1309	transcriptional regulator
JCR16_00980	COG0351	phosphomethylpyrimidine kinase
JCR16_00980	COG0352	thiamine-phosphate diphosphorylase activity
JCR16_00980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JCR16_00990	COG2814	Major facilitator Superfamily
JCR16_01005	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
JCR16_01015	COG1113	amino acid transport
JCR16_01025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JCR16_01030	COG1012	belongs to the aldehyde dehydrogenase family
JCR16_01040	COG1335	isochorismatase
JCR16_01070	COG2814	Major facilitator Superfamily
JCR16_01075	COG0583	DNA-binding transcription factor activity
JCR16_01095	COG0667	Aldo Keto reductase
JCR16_01130	COG1733	regulation of RNA biosynthetic process
JCR16_01135	COG2249	NAD(P)H dehydrogenase (quinone) activity
JCR16_01200	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JCR16_01215	COG2329	Antibiotic biosynthesis monooxygenase
JCR16_01245	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JCR16_01275	COG0427	acetyl-CoA hydrolase
JCR16_01300	COG0659	secondary active sulfate transmembrane transporter activity
JCR16_01305	COG4221	oxidoreductase activity
JCR16_01310	COG2873	o-acetylhomoserine
JCR16_01315	COG0488	(ABC) transporter
JCR16_01400	COG0833	amino acid
JCR16_01445	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JCR16_01450	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JCR16_01465	COG2226	methyltransferase
JCR16_01515	COG0067	glutamate synthase
JCR16_01515	COG0070	glutamate synthase
JCR16_01515	COG0069	glutamate synthase activity
JCR16_01520	COG0493	'glutamate synthase
JCR16_01530	COG1704	LemA family
JCR16_01535	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
JCR16_01555	COG3307	-O-antigen
JCR16_01575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JCR16_01590	COG0194	GDP metabolic process
JCR16_01640	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JCR16_01660	COG5380	lipid catabolic process
JCR16_01665	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JCR16_01690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JCR16_01695	COG0277	FAD linked oxidase domain protein
JCR16_01705	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
JCR16_01710	COG2249	NAD(P)H dehydrogenase (quinone) activity
JCR16_01725	COG1289	transmembrane transporter activity
JCR16_01735	COG0628	permease
JCR16_01740	COG1192	Involved in chromosome partitioning
JCR16_01770	COG0833	amino acid
JCR16_01775	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JCR16_01780	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JCR16_01790	COG1012	belongs to the aldehyde dehydrogenase family
JCR16_01830	COG0583	DNA-binding transcription factor activity
JCR16_01875	COG0517	IMP dehydrogenase activity
JCR16_01880	COG1983	PspC domain protein
JCR16_01890	COG1960	acyl-CoA dehydrogenase activity
JCR16_01905	COG0408	coproporphyrinogen oxidase activity
JCR16_01925	COG0513	Belongs to the DEAD box helicase family
JCR16_01935	COG1127	ABC transporter
JCR16_01940	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JCR16_01950	COG2854	intermembrane phospholipid transfer
JCR16_01960	COG0598	Magnesium transport protein CorA
JCR16_01970	COG0494	nUDIX hydrolase
JCR16_01975	COG1040	competence protein
JCR16_01980	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JCR16_02000	COG1946	Acyl-CoA thioesterase
JCR16_02005	COG1301	dicarboxylic acid transport
JCR16_02020	COG1959	2 iron, 2 sulfur cluster binding
JCR16_02025	COG1017	nitric oxide dioxygenase activity
JCR16_02025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JCR16_02030	COG0433	COG0433 Predicted ATPase
JCR16_02035	COG0626	cystathionine gamma-synthase activity
JCR16_02190	COG1960	acyl-CoA dehydrogenase activity
JCR16_02195	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
JCR16_02225	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
JCR16_02230	COG0339	signal peptide processing
JCR16_02235	COG0557	exoribonuclease II activity
JCR16_02280	COG0179	Fumarylacetoacetate (FAA) hydrolase
JCR16_02285	COG2169	Transcriptional regulator
JCR16_02290	COG0697	spore germination
JCR16_02295	COG1295	ribonuclease BN
JCR16_02330	COG1702	phosphate starvation-inducible protein PhoH
JCR16_02340	COG1196	nuclear chromosome segregation
JCR16_02340	COG0741	lytic transglycosylase activity
JCR16_02340	COG0739	heme binding
JCR16_02370	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
JCR16_02375	COG1183	phosphatidylcholine synthase activity
JCR16_02420	COG1960	acyl-CoA dehydrogenase activity
JCR16_02425	COG1309	transcriptional regulator
JCR16_02440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JCR16_02445	COG1960	acyl-CoA dehydrogenase activity
JCR16_02465	COG2969	positive regulation of protein catabolic process
JCR16_02475	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JCR16_02490	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JCR16_02495	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JCR16_02515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JCR16_02525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JCR16_02530	COG1408	metallophosphoesterase
JCR16_02540	COG2199	diguanylate cyclase activity
JCR16_02600	COG1607	acyl-coa hydrolase
JCR16_02630	COG2350	Protein conserved in bacteria
JCR16_02640	COG0613	PHP domain protein
JCR16_02645	COG3781	membrane
JCR16_02655	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JCR16_02660	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JCR16_02670	COG1862	Preprotein translocase
JCR16_02700	COG2205	protein histidine kinase activity
JCR16_02705	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JCR16_02725	COG0726	polysaccharide deacetylase
JCR16_02730	COG0463	Glycosyl transferase, family 2
JCR16_02735	COG0438	transferase activity, transferring glycosyl groups
JCR16_02800	COG0625	glutathione transferase activity
JCR16_02805	COG0583	DNA-binding transcription factor activity
JCR16_02810	COG1960	acyl-CoA dehydrogenase activity
JCR16_02815	COG1960	acyl-CoA dehydrogenase activity
JCR16_02825	COG2205	protein histidine kinase activity
JCR16_02830	COG0745	RESPONSE REGULATOR receiver
JCR16_02835	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
JCR16_02855	COG2096	Adenosyltransferase
JCR16_02905	COG0285	dihydrofolate synthase activity
JCR16_02925	COG0450	alkyl hydroperoxide reductase
JCR16_02940	COG0477	Major facilitator Superfamily
JCR16_02945	COG1272	protein, Hemolysin III
JCR16_02975	COG0183	Belongs to the thiolase family
JCR16_02980	COG2207	Transcriptional regulator
JCR16_03000	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JCR16_03020	COG0183	Belongs to the thiolase family
JCR16_03030	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
JCR16_03030	COG2885	chlorophyll binding
JCR16_03040	COG1690	Belongs to the RtcB family
JCR16_03045	COG0833	amino acid
JCR16_03055	COG2233	PERMEase
JCR16_03060	COG1217	gtp-binding protein TYPA
JCR16_03085	COG2094	Belongs to the DNA glycosylase MPG family
JCR16_03090	COG4772	TonB-dependent receptor
JCR16_03105	COG1902	pentaerythritol trinitrate reductase activity
JCR16_03110	COG0679	Auxin Efflux Carrier
JCR16_03120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JCR16_03125	COG0354	folic acid binding
JCR16_03135	COG3189	MarR family transcriptional regulator
JCR16_03140	COG2824	Alkylphosphonate utilization operon protein PhnA
JCR16_03145	COG3422	double-strand break repair
JCR16_03185	COG0840	transmembrane signaling receptor activity
JCR16_03205	COG5510	response to toxic substance
JCR16_03215	COG2832	Protein of unknown function (DUF454)
JCR16_03220	COG1376	ErfK ybiS ycfS ynhG family protein
JCR16_03260	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JCR16_03270	COG1289	transmembrane transporter activity
JCR16_03275	COG2814	Major facilitator Superfamily
JCR16_03295	COG1115	amino acid carrier protein
JCR16_03300	COG1752	Esterase of the alpha-beta hydrolase superfamily
JCR16_03305	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JCR16_03310	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
JCR16_03340	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JCR16_03350	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JCR16_03355	COG1077	Cell shape determining protein MreB Mrl
JCR16_03360	COG1792	Involved in formation and maintenance of cell shape
JCR16_03365	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JCR16_03370	COG0424	maF-like protein
JCR16_03375	COG1530	ribonuclease E activity
JCR16_03385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JCR16_03395	COG0560	Phosphoserine phosphatase
JCR16_03405	COG2249	NAD(P)H dehydrogenase (quinone) activity
JCR16_03430	COG2207	Transcriptional regulator
JCR16_03450	COG1113	amino acid transport
JCR16_03455	COG2828	Protein conserved in bacteria
JCR16_03460	COG0142	geranyltranstransferase activity
JCR16_03465	COG2315	Protein conserved in bacteria
JCR16_03480	COG1752	Esterase of the alpha-beta hydrolase superfamily
JCR16_03515	COG0745	RESPONSE REGULATOR receiver
JCR16_03520	COG0642	Histidine kinase
JCR16_03530	COG0004	ammonium transporteR
JCR16_03535	COG0583	DNA-binding transcription factor activity
JCR16_03555	COG0525	valine-tRNA ligase activity
JCR16_03565	COG1028	Short-chain dehydrogenase reductase Sdr
JCR16_03575	COG0393	Putative heavy-metal-binding
JCR16_03580	COG0393	Putative heavy-metal-binding
JCR16_03585	COG1538	Outer membrane efflux protein
JCR16_03595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JCR16_03600	COG0671	phosphoesterase, PA-phosphatase related
JCR16_03630	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JCR16_03645	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JCR16_03645	COG1648	precorrin-2 dehydrogenase activity
JCR16_03650	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JCR16_03655	COG1733	regulation of RNA biosynthetic process
JCR16_03665	COG0531	amino acid
JCR16_03680	COG0321	lipoyl(octanoyl) transferase activity
JCR16_03685	COG2921	Belongs to the UPF0250 family
JCR16_03725	COG2009	succinate dehydrogenase
JCR16_03730	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
JCR16_03735	COG1053	succinate dehydrogenase
JCR16_03740	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JCR16_03765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JCR16_03785	COG2354	Protein conserved in bacteria
JCR16_03790	COG2321	neutral zinc metallopeptidase
JCR16_03830	COG2843	Capsule synthesis protein
JCR16_03845	COG0589	response to stress
JCR16_03865	COG0505	Belongs to the CarA family
JCR16_03890	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JCR16_03895	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JCR16_03945	COG0477	Major facilitator Superfamily
JCR16_03950	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JCR16_03965	COG1597	lipid kinase activity
JCR16_03970	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JCR16_04000	COG0584	glycerophosphoryl diester phosphodiesterase
JCR16_04020	COG0741	lytic transglycosylase activity
JCR16_04040	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JCR16_04055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JCR16_04130	COG3267	Type II secretory pathway component ExeA
JCR16_04130	COG3409	Peptidoglycan-binding domain 1 protein
JCR16_04160	COG0681	Belongs to the peptidase S26 family
JCR16_04195	COG4373	Mu-like prophage FluMu protein gp28
JCR16_04210	COG4383	Mu-like prophage protein gp29
JCR16_04215	COG2369	cell adhesion
JCR16_04220	COG5005	Phage virion morphogenesis
JCR16_04235	COG4397	Mu-like prophage major head subunit gpT
JCR16_04330	COG0778	Nitroreductase
JCR16_04345	COG1929	Belongs to the glycerate kinase type-1 family
JCR16_04350	COG0243	molybdopterin cofactor binding
JCR16_04355	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JCR16_04360	COG3339	Conserved Protein
JCR16_04370	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
JCR16_04385	COG1113	amino acid transport
JCR16_04395	COG0019	diaminopimelate decarboxylase activity
JCR16_04405	COG1280	lysine exporter protein (LysE YggA)
JCR16_04410	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
JCR16_04440	COG0463	Glycosyl transferase, family 2
JCR16_04460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JCR16_04495	COG4591	ABC-type transport system involved in lipoprotein release permease component
JCR16_04500	COG1136	(ABC) transporter
JCR16_04505	COG0658	competence protein
JCR16_04505	COG2333	competence protein COMEC
JCR16_04515	COG0616	signal peptide processing
JCR16_04515	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JCR16_04520	COG0596	Alpha beta hydrolase
JCR16_04525	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JCR16_04535	COG0628	permease
JCR16_04575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JCR16_04595	COG0823	Involved in the tonB-independent uptake of proteins
JCR16_04615	COG0824	Thioesterase
JCR16_04620	COG1473	amidohydrolase
JCR16_04640	COG0047	phosphoribosylformylglycinamidine synthase activity
JCR16_04640	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JCR16_04645	COG2814	Major facilitator Superfamily
JCR16_04655	COG1024	Enoyl-CoA hydratase
JCR16_04660	COG1056	cytidyltransferase-related domain
JCR16_04660	COG1051	belongs to the nudix hydrolase family
JCR16_04670	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JCR16_04685	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JCR16_04700	COG4625	pathogenesis
JCR16_04705	COG0583	DNA-binding transcription factor activity
JCR16_04710	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JCR16_04715	COG4208	sulfate ABC transporter
JCR16_04720	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
JCR16_04730	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JCR16_04735	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JCR16_04740	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JCR16_04760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JCR16_04775	COG0681	Belongs to the peptidase S26 family
JCR16_04790	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JCR16_04800	COG1381	Involved in DNA repair and RecF pathway recombination
JCR16_04805	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
JCR16_04815	COG4221	oxidoreductase activity
JCR16_04850	COG0436	Aminotransferase
JCR16_04870	COG0556	nucleotide-excision repair
JCR16_04925	COG2070	2-Nitropropane dioxygenase
JCR16_04955	COG1215	transferase activity, transferring glycosyl groups
JCR16_04970	COG0415	Belongs to the DNA photolyase family
JCR16_04980	COG1252	NADH dehydrogenase
JCR16_04985	COG1686	Belongs to the peptidase S11 family
JCR16_05000	COG1187	pseudouridine synthase activity
JCR16_05025	COG0477	Major facilitator Superfamily
JCR16_05030	COG0583	DNA-binding transcription factor activity
JCR16_05035	COG1823	symporter activity
JCR16_05045	COG0612	Peptidase, M16
JCR16_05070	COG0352	thiamine-phosphate diphosphorylase activity
JCR16_05105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JCR16_05120	COG1309	transcriptional regulator
JCR16_05130	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JCR16_05135	COG0076	glutamate decarboxylase activity
JCR16_05145	COG1522	sequence-specific DNA binding
JCR16_05150	COG3961	Belongs to the TPP enzyme family
JCR16_05155	COG1113	amino acid transport
JCR16_05160	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JCR16_05165	COG0573	inorganic phosphate transmembrane transporter activity
JCR16_05175	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JCR16_05180	COG0616	signal peptide processing
JCR16_05215	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JCR16_05220	COG1686	Belongs to the peptidase S11 family
JCR16_05245	COG0583	DNA-binding transcription factor activity
JCR16_05250	COG1067	ATP-dependent peptidase activity
JCR16_05295	COG1966	Carbon starvation protein
JCR16_05300	COG2879	small protein
JCR16_05330	COG2508	Transcriptional regulator
JCR16_05330	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JCR16_05350	COG1113	amino acid transport
JCR16_05355	COG0583	DNA-binding transcription factor activity
JCR16_05360	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JCR16_05365	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JCR16_05375	COG1012	belongs to the aldehyde dehydrogenase family
JCR16_05380	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JCR16_05385	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
JCR16_05385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JCR16_05420	COG2814	Major facilitator Superfamily
JCR16_05425	COG4948	Mandelate Racemase Muconate Lactonizing
JCR16_05435	COG1309	transcriptional regulator
JCR16_05455	COG1741	Belongs to the pirin family
JCR16_05465	COG2964	Protein conserved in bacteria
JCR16_05480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JCR16_05485	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JCR16_05490	COG4605	iron ion homeostasis
JCR16_05495	COG4604	ABC transporter, ATP-binding protein
JCR16_05500	COG4607	ABC-type enterochelin transport system periplasmic component
JCR16_05505	COG4774	siderophore transport
JCR16_05515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JCR16_05520	COG1021	2,3-dihydroxybenzoate-AMP ligase
JCR16_05525	COG1535	isochorismatase
JCR16_05525	COG3433	isochorismatase activity
JCR16_05540	COG1132	(ABC) transporter
JCR16_05545	COG1132	(ABC) transporter
JCR16_05570	COG1169	isochorismate synthase
JCR16_05585	COG3739	integral membrane protein
JCR16_05610	COG0302	gtp cyclohydrolase
JCR16_05620	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JCR16_05650	COG0308	aminopeptidase N
JCR16_05655	COG0512	Glutamine amidotransferase of anthranilate synthase
JCR16_05860	COG5410	chromosome segregation
JCR16_06335	COG1598	PFAM Uncharacterised protein family UPF0150
JCR16_06390	COG0582	viral genome integration into host DNA
JCR16_06405	COG0174	glutamine synthetase
JCR16_06415	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JCR16_06450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JCR16_06455	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JCR16_06460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JCR16_06480	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JCR16_06485	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JCR16_06490	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
JCR16_06505	COG1960	acyl-CoA dehydrogenase activity
JCR16_06510	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JCR16_06515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JCR16_06525	COG2223	nitrite transmembrane transporter activity
JCR16_06535	COG0024	Methionine aminopeptidase
JCR16_06540	COG0052	Belongs to the universal ribosomal protein uS2 family
JCR16_06555	COG2207	Transcriptional regulator
JCR16_06580	COG2951	lytic endotransglycosylase activity
JCR16_06585	COG0772	Belongs to the SEDS family
JCR16_06600	COG0842	Transport permease protein
JCR16_06605	COG1131	(ABC) transporter
JCR16_06650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JCR16_06665	COG4215	(ABC) transporter
JCR16_06670	COG4160	amino acid transport
JCR16_06675	COG4598	ABC transporter
JCR16_06685	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JCR16_06690	COG0826	peptidase U32
JCR16_06695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JCR16_06710	COG1720	tRNA m6t6A37 methyltransferase activity
JCR16_06720	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JCR16_06735	COG0642	Histidine kinase
JCR16_06745	COG0494	nUDIX hydrolase
JCR16_06755	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JCR16_06760	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JCR16_06765	COG3139	Protein of unknown function (DUF1315)
JCR16_06770	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JCR16_06775	COG1301	dicarboxylic acid transport
JCR16_06780	COG1960	acyl-CoA dehydrogenase activity
JCR16_06785	COG2819	hydrolase of the alpha beta superfamily
JCR16_06795	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JCR16_06810	COG1234	tRNA 3'-trailer cleavage
JCR16_06840	COG2363	Small membrane protein
JCR16_06860	COG0513	Belongs to the DEAD box helicase family
JCR16_06870	COG0778	Nitroreductase
JCR16_06900	COG1286	toxin biosynthetic process
JCR16_06925	COG4783	chaperone-mediated protein folding
JCR16_06930	COG1610	YqeY-like protein
JCR16_07030	COG3111	PFAM Bacterial OB fold (BOF) protein
JCR16_07055	COG3243	poly(R)-hydroxyalkanoic acid synthase
JCR16_07060	COG0786	glutamate:sodium symporter activity
JCR16_07070	COG2186	Transcriptional regulator
JCR16_07120	COG0477	Major facilitator Superfamily
JCR16_07145	COG2985	domain, Protein
JCR16_07155	COG2995	paraquat-inducible protein a
JCR16_07160	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JCR16_07160	COG3008	intermembrane lipid transfer
JCR16_07170	COG1794	racemase activity, acting on amino acids and derivatives
JCR16_07240	COG0482	sulfurtransferase activity
JCR16_07255	COG0488	(ABC) transporter
JCR16_07260	COG3173	Aminoglycoside phosphotransferase
JCR16_07270	COG2433	Pfam Transposase IS66
JCR16_07315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JCR16_07320	COG2011	ABC-type metal ion transport system permease component
JCR16_07325	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JCR16_07330	COG1464	Belongs to the NlpA lipoprotein family
JCR16_07335	COG0151	Belongs to the GarS family
JCR16_07340	COG0138	bifunctional purine biosynthesis protein purh
JCR16_07345	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
JCR16_07375	COG2308	Evidence 4 Homologs of previously reported genes of
JCR16_07385	COG1305	Transglutaminase-like
JCR16_07395	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JCR16_07400	COG0305	Participates in initiation and elongation during chromosome replication
JCR16_07425	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JCR16_07435	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JCR16_07440	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JCR16_07465	COG0726	polysaccharide deacetylase
JCR16_07465	COG1649	PFAM Uncharacterised BCR, COG1649
JCR16_07470	COG1215	transferase activity, transferring glycosyl groups
JCR16_07485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JCR16_07500	COG0583	DNA-binding transcription factor activity
JCR16_07520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JCR16_07525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JCR16_07540	COG1960	acyl-CoA dehydrogenase activity
JCR16_07545	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JCR16_07550	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JCR16_07575	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
JCR16_07580	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
JCR16_07590	COG2205	protein histidine kinase activity
JCR16_07595	COG0745	RESPONSE REGULATOR receiver
JCR16_07600	COG0174	glutamine synthetase
JCR16_07620	COG0729	surface antigen
JCR16_07645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JCR16_07650	COG2814	Major facilitator Superfamily
JCR16_07665	COG0583	DNA-binding transcription factor activity
JCR16_07680	COG1187	pseudouridine synthase activity
JCR16_07700	COG0802	atpase or kinase
JCR16_07705	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JCR16_07715	COG1923	regulation of RNA biosynthetic process
JCR16_07720	COG0697	spore germination
JCR16_07735	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JCR16_07745	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JCR16_07750	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JCR16_07750	COG0519	Catalyzes the synthesis of GMP from XMP
JCR16_07755	COG4302	ethanolamine ammonia-lyase activity
JCR16_07760	COG4303	Ethanolamine ammonia lyase large subunit
JCR16_07765	COG0531	amino acid
JCR16_07785	COG1454	alcohol dehydrogenase
JCR16_07790	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JCR16_07800	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
JCR16_07820	COG0308	aminopeptidase N
JCR16_07830	COG4221	oxidoreductase activity
JCR16_07840	COG1605	Chorismate mutase
JCR16_07855	COG1309	transcriptional regulator
JCR16_07865	COG0668	transmembrane transport
JCR16_07900	COG4773	Receptor
JCR16_07920	COG0488	(ABC) transporter
JCR16_07925	COG0589	response to stress
JCR16_07950	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JCR16_07960	COG3135	benzoate transporter
JCR16_07965	COG1522	sequence-specific DNA binding
JCR16_07975	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JCR16_07980	COG0583	DNA-binding transcription factor activity
JCR16_07990	COG0183	Belongs to the thiolase family
JCR16_08000	COG2030	dehydratase
JCR16_08005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JCR16_08020	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JCR16_08030	COG0824	Thioesterase
JCR16_08035	COG1454	alcohol dehydrogenase
JCR16_08045	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JCR16_08065	COG0069	glutamate synthase activity
JCR16_08085	COG2814	Major facilitator Superfamily
JCR16_08100	COG0511	ligase activity, forming carbon-carbon bonds
JCR16_08120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JCR16_08120	COG1116	anion transmembrane transporter activity
JCR16_08125	COG0745	RESPONSE REGULATOR receiver
JCR16_08135	COG2146	nitrite reductase [NAD(P)H] activity
JCR16_08135	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JCR16_08140	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JCR16_08145	COG0243	molybdopterin cofactor binding
JCR16_08155	COG0243	molybdopterin cofactor binding
JCR16_08160	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JCR16_08175	COG0521	Mo-molybdopterin cofactor biosynthetic process
JCR16_08175	COG0315	cyclic pyranopterin monophosphate synthase activity
JCR16_08180	COG0303	'Molybdopterin
JCR16_08190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JCR16_08195	COG0697	spore germination
JCR16_08215	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
JCR16_08220	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JCR16_08275	COG2204	response regulator
JCR16_08280	COG3852	Histidine kinase
JCR16_08300	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JCR16_08305	COG0575	Belongs to the CDS family
JCR16_08340	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JCR16_08355	COG2137	regulation of response to DNA damage stimulus
JCR16_08365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JCR16_08370	COG1011	Hydrolase
JCR16_08395	COG1522	sequence-specific DNA binding
JCR16_08405	COG1113	amino acid transport
JCR16_08420	COG0659	secondary active sulfate transmembrane transporter activity
JCR16_08425	COG2135	peptidase activity
JCR16_08440	COG3300	MHYT domain
JCR16_08440	COG5001	Diguanylate cyclase
JCR16_08460	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JCR16_08460	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JCR16_08460	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
JCR16_08465	COG1105	Belongs to the carbohydrate kinase PfkB family
JCR16_08470	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JCR16_08470	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JCR16_08500	COG0024	Methionine aminopeptidase
JCR16_08505	COG0583	DNA-binding transcription factor activity
JCR16_08515	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JCR16_08520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JCR16_08525	COG0516	GMP reductase activity
JCR16_08525	COG0517	IMP dehydrogenase activity
JCR16_08550	COG0552	protein localization to endoplasmic reticulum
JCR16_08560	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
JCR16_08575	COG4890	Cyd operon protein YbgT
JCR16_08580	COG1294	oxidase, subunit
JCR16_08600	COG1585	Membrane protein implicated in regulation of membrane protease activity
JCR16_08610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JCR16_08615	COG4774	siderophore transport
JCR16_08630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JCR16_08635	COG0569	domain protein
JCR16_08640	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JCR16_08670	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JCR16_08675	COG0542	response to heat
JCR16_08700	COG1902	pentaerythritol trinitrate reductase activity
JCR16_08700	COG0446	pyridine nucleotide-disulphide oxidoreductase
JCR16_08745	COG2323	membrane
JCR16_08750	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
JCR16_08760	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JCR16_08765	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JCR16_08770	COG0183	Belongs to the thiolase family
JCR16_08775	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JCR16_08780	COG0596	Alpha beta hydrolase
JCR16_08785	COG2271	Major facilitator Superfamily
JCR16_08790	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JCR16_08795	COG3485	protocatechuate 3,4-dioxygenase
JCR16_08800	COG3485	protocatechuate 3,4-dioxygenase
JCR16_08805	COG0710	3-dehydroquinate dehydratase activity
JCR16_08810	COG3420	alginic acid biosynthetic process
JCR16_08815	COG3659	wide pore channel activity
JCR16_08820	COG4993	Dehydrogenase
JCR16_08830	COG2391	methyltransferase activity
JCR16_08845	COG1414	Transcriptional regulator
JCR16_08850	COG0583	DNA-binding transcription factor activity
JCR16_08855	COG1960	acyl-CoA dehydrogenase activity
JCR16_08880	COG2814	Major facilitator Superfamily
JCR16_08890	COG0154	amidase activity
JCR16_08910	COG4638	Rieske (2fe-2S)
JCR16_08920	COG1028	Short-chain dehydrogenase reductase Sdr
JCR16_08930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JCR16_08940	COG3733	amine oxidase
JCR16_08950	COG1012	belongs to the aldehyde dehydrogenase family
JCR16_08960	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JCR16_08965	COG0183	Belongs to the thiolase family
JCR16_08970	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JCR16_08975	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JCR16_08985	COG4829	muconolactone delta-isomerase
JCR16_08990	COG4948	Mandelate Racemase Muconate Lactonizing
JCR16_08995	COG0583	DNA-binding transcription factor activity
JCR16_09005	COG2186	Transcriptional regulator
JCR16_09025	COG1012	belongs to the aldehyde dehydrogenase family
JCR16_09045	COG1960	acyl-CoA dehydrogenase activity
JCR16_09050	COG1028	Short-chain dehydrogenase reductase Sdr
JCR16_09055	COG3829	transcription factor binding
JCR16_09065	COG3162	membrane
JCR16_09080	COG1012	belongs to the aldehyde dehydrogenase family
JCR16_09095	COG0753	catalase activity
JCR16_09115	COG1846	Transcriptional regulator
JCR16_09120	COG0446	pyridine nucleotide-disulphide oxidoreductase
JCR16_09120	COG1902	pentaerythritol trinitrate reductase activity
JCR16_09130	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JCR16_09160	COG1309	transcriptional regulator
JCR16_09170	COG1335	isochorismatase
JCR16_09175	COG0583	DNA-binding transcription factor activity
JCR16_09185	COG0475	glutathione-regulated potassium exporter activity
JCR16_09185	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JCR16_09195	COG1473	amidohydrolase
JCR16_09205	COG2831	hemolysin activation secretion protein
JCR16_09210	COG3210	domain, Protein
JCR16_09240	COG2188	Transcriptional regulator
JCR16_09255	COG0583	DNA-binding transcription factor activity
JCR16_09285	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JCR16_09305	COG1566	PFAM secretion protein HlyD family protein
JCR16_09320	COG1012	belongs to the aldehyde dehydrogenase family
JCR16_09325	COG0129	dihydroxy-acid dehydratase activity
JCR16_09335	COG0583	DNA-binding transcription factor activity
JCR16_09340	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JCR16_09350	COG2084	Dehydrogenase
JCR16_09355	COG2207	Transcriptional regulator
JCR16_09370	COG1064	alcohol dehydrogenase
JCR16_09380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JCR16_09385	COG1120	ATPase activity
JCR16_09405	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JCR16_09520	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JCR16_09575	COG1028	Short-chain dehydrogenase reductase Sdr
JCR16_09590	COG2207	Transcriptional regulator
JCR16_09600	COG2205	protein histidine kinase activity
JCR16_09605	COG0745	RESPONSE REGULATOR receiver
JCR16_09610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JCR16_09615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JCR16_09620	COG1538	Outer membrane efflux protein
JCR16_09630	COG2072	flavoprotein involved in K transport
JCR16_09650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JCR16_09670	COG3539	Fimbrial protein
JCR16_09700	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
JCR16_09710	COG0753	catalase activity
JCR16_09725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JCR16_09785	COG3433	isochorismatase activity
JCR16_09785	COG1535	isochorismatase
JCR16_09790	COG1028	Short-chain dehydrogenase reductase Sdr
JCR16_09795	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
JCR16_09800	COG4149	molybdate abc transporter
JCR16_09805	COG0725	ABC transporter, periplasmic molybdate-binding protein
JCR16_09815	COG4638	Rieske (2fe-2S)
JCR16_09820	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
JCR16_09825	COG0543	2 iron, 2 sulfur cluster binding
JCR16_09825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JCR16_09850	COG1028	Short-chain dehydrogenase reductase Sdr
JCR16_09865	COG2207	Transcriptional regulator
JCR16_09875	COG1028	Short-chain dehydrogenase reductase Sdr
JCR16_09880	COG2610	gluconate transmembrane transporter activity
JCR16_09890	COG0583	DNA-binding transcription factor activity
JCR16_09900	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JCR16_09905	COG2031	fatty acid transporter
JCR16_09910	COG0183	Belongs to the thiolase family
JCR16_09915	COG0583	DNA-binding transcription factor activity
JCR16_09920	COG0583	DNA-binding transcription factor activity
JCR16_09935	COG1027	Aspartate ammonia-lyase
JCR16_09945	COG0477	Major facilitator Superfamily
JCR16_09965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JCR16_09970	COG4521	taurine ABC transporter
JCR16_09985	COG2188	Transcriptional regulator
JCR16_09995	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JCR16_10000	COG1733	regulation of RNA biosynthetic process
JCR16_10005	COG2207	Transcriptional regulator
JCR16_10005	COG3708	Transcriptional regulator
JCR16_10020	COG0730	response to heat
JCR16_10030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JCR16_10030	COG3453	Protein conserved in bacteria
JCR16_10040	COG3781	membrane
JCR16_10045	COG1063	alcohol dehydrogenase
JCR16_10055	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JCR16_10060	COG0508	dehydrogenase complex catalyzes the overall conversion of
JCR16_10065	COG0022	dehydrogenase e1 component
JCR16_10070	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JCR16_10075	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JCR16_10090	COG3706	GGDEF domain
JCR16_10105	COG0133	tryptophan synthase activity
JCR16_10115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JCR16_10150	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JCR16_10175	COG2226	methyltransferase
JCR16_10230	COG0842	Transport permease protein
JCR16_10235	COG0842	Transport permease protein
JCR16_10240	COG1131	(ABC) transporter
JCR16_10255	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JCR16_10260	COG4773	Receptor
JCR16_10280	COG0730	response to heat
JCR16_10285	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JCR16_10305	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
JCR16_10320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JCR16_10360	COG4264	IucA IucC family
JCR16_10365	COG4264	IucA IucC family
JCR16_10385	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JCR16_10400	COG1960	acyl-CoA dehydrogenase activity
JCR16_10405	COG1960	acyl-CoA dehydrogenase activity
JCR16_10410	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JCR16_10415	COG2207	Transcriptional regulator
JCR16_10420	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JCR16_10425	COG0776	regulation of translation
JCR16_10450	COG0822	iron-sulfur transferase activity
JCR16_10455	COG0316	Belongs to the HesB IscA family
JCR16_10485	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JCR16_10505	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JCR16_10510	COG0702	epimerase
JCR16_10545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JCR16_10555	COG0339	signal peptide processing
JCR16_10605	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JCR16_10610	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
JCR16_10640	COG0776	regulation of translation
JCR16_10705	COG0084	hydrolase, TatD family'
JCR16_10725	COG1663	tetraacyldisaccharide 4'-kinase activity
JCR16_10730	COG1132	(ABC) transporter
JCR16_10740	COG0811	peptide transport
JCR16_10745	COG1475	DNA binding
JCR16_10750	COG1192	Involved in chromosome partitioning
JCR16_10760	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JCR16_10775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JCR16_10780	COG0191	fructose-bisphosphate aldolase activity
JCR16_10800	COG0424	maF-like protein
JCR16_10805	COG2850	peptidyl-arginine hydroxylation
JCR16_10815	COG0640	Transcriptional regulator
JCR16_10825	COG3619	membrane
JCR16_10830	COG3122	Protein conserved in bacteria
JCR16_10835	COG1132	(ABC) transporter
JCR16_10855	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JCR16_10860	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JCR16_10870	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
JCR16_10870	COG0506	proline dehydrogenase activity
JCR16_10870	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
JCR16_10875	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JCR16_10890	COG3698	Phosphodiester glycosidase
JCR16_10900	COG2353	YceI-like domain
JCR16_10910	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JCR16_10955	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JCR16_10955	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JCR16_10980	COG3539	Fimbrial protein
JCR16_10985	COG3121	Chaperone
JCR16_11010	COG0697	spore germination
JCR16_11020	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JCR16_11040	COG0583	DNA-binding transcription factor activity
JCR16_11060	COG1309	transcriptional regulator
JCR16_11080	COG1522	sequence-specific DNA binding
JCR16_11090	COG1126	abc transporter atp-binding protein
JCR16_11095	COG0765	amino acid transport
JCR16_11100	COG0765	amino acid transport
JCR16_11130	COG1464	Belongs to the NlpA lipoprotein family
JCR16_11140	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JCR16_11145	COG2011	ABC-type metal ion transport system permease component
JCR16_11150	COG0012	GTP binding
JCR16_11175	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
JCR16_11215	COG0386	Belongs to the glutathione peroxidase family
JCR16_11225	COG0436	Aminotransferase
JCR16_11265	COG3634	alkyl hydroperoxide reductase activity
JCR16_11280	COG0583	DNA-binding transcription factor activity
JCR16_11285	COG0798	PFAM Bile acid sodium symporter
JCR16_11290	COG0640	Transcriptional regulator
JCR16_11305	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JCR16_11315	COG0583	DNA-binding transcription factor activity
JCR16_11325	COG1953	Uracil, thiamine, allantoin
JCR16_11335	COG2175	clavaminate synthase activity
JCR16_11340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JCR16_11345	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
JCR16_11350	COG4521	taurine ABC transporter
JCR16_11360	COG0477	Major facilitator Superfamily
JCR16_11380	COG1271	oxidase subunit
JCR16_11385	COG1294	oxidase, subunit
JCR16_11395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JCR16_11415	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JCR16_11435	COG3052	prosthetic group binding
JCR16_11440	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
JCR16_11450	COG2814	Major facilitator Superfamily
JCR16_11470	COG1346	cytolysis
JCR16_11480	COG0583	DNA-binding transcription factor activity
JCR16_11485	COG0625	glutathione transferase activity
JCR16_11490	COG0625	glutathione transferase activity
JCR16_11495	COG0583	DNA-binding transcription factor activity
JCR16_11510	COG1045	serine acetyltransferase
JCR16_11515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JCR16_11520	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JCR16_11530	COG1280	lysine exporter protein (LysE YggA)
JCR16_11545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JCR16_11550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JCR16_11555	COG1126	abc transporter atp-binding protein
JCR16_11560	COG0765	amino acid transport
JCR16_11565	COG0765	amino acid transport
JCR16_11585	COG2205	protein histidine kinase activity
JCR16_11585	COG0784	Response regulator, receiver
JCR16_11605	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JCR16_11625	COG1028	Short-chain dehydrogenase reductase Sdr
JCR16_11675	COG0583	DNA-binding transcription factor activity
JCR16_11695	COG0318	PFAM AMP-dependent synthetase and ligase
JCR16_11700	COG1309	transcriptional regulator
JCR16_11705	COG1960	acyl-CoA dehydrogenase activity
JCR16_11710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JCR16_11715	COG1024	Enoyl-CoA hydratase
JCR16_11720	COG4770	biotin carboxylase activity
JCR16_11730	COG0583	DNA-binding transcription factor activity
JCR16_11745	COG1960	acyl-CoA dehydrogenase activity
JCR16_11755	COG2814	Major facilitator Superfamily
JCR16_11765	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JCR16_11770	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JCR16_11775	COG2814	Major facilitator Superfamily
JCR16_11780	COG1960	acyl-CoA dehydrogenase activity
JCR16_11785	COG1024	Enoyl-CoA hydratase
JCR16_11790	COG1028	Short-chain dehydrogenase reductase Sdr
JCR16_11795	COG1250	3-hydroxyacyl-CoA dehydrogenase
JCR16_11800	COG0183	Belongs to the thiolase family
JCR16_11810	COG2814	Major facilitator Superfamily
JCR16_11820	COG1024	Enoyl-CoA hydratase
JCR16_11835	COG1960	acyl-CoA dehydrogenase activity
JCR16_11840	COG2814	Major facilitator Superfamily
JCR16_11845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JCR16_11850	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JCR16_11865	COG3842	ATPase activity
JCR16_11870	COG1840	ABC-type Fe3 transport system, periplasmic component
JCR16_11880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JCR16_11885	COG1414	Transcriptional regulator
JCR16_11895	COG0583	DNA-binding transcription factor activity
JCR16_11900	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JCR16_11905	COG1012	belongs to the aldehyde dehydrogenase family
JCR16_11915	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JCR16_11925	COG1012	belongs to the aldehyde dehydrogenase family
JCR16_11930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JCR16_11935	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JCR16_11940	COG2267	carboxylic ester hydrolase activity
JCR16_11960	COG3038	cytochrome b561
JCR16_11965	COG0753	catalase activity
JCR16_12000	COG2050	protein possibly involved in aromatic compounds catabolism
JCR16_12010	COG3327	negative regulation of DNA-templated transcription, initiation
JCR16_12015	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
JCR16_12020	COG0183	Belongs to the thiolase family
JCR16_12025	COG1250	3-hydroxyacyl-CoA dehydrogenase
JCR16_12030	COG1024	Enoyl-CoA hydratase
JCR16_12035	COG1024	Enoyl-CoA hydratase
JCR16_12040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JCR16_12045	COG2151	metal-sulfur cluster biosynthetic enzyme
JCR16_12050	COG3396	Phenylacetate-CoA oxygenase
JCR16_12055	COG3460	Phenylacetate-CoA oxygenase
JCR16_12060	COG3396	Phenylacetate-CoA oxygenase
JCR16_12065	COG2030	dehydratase
JCR16_12065	COG1012	belongs to the aldehyde dehydrogenase family
JCR16_12070	COG1760	l-serine dehydratase
JCR16_12075	COG0531	amino acid
JCR16_12080	COG1012	belongs to the aldehyde dehydrogenase family
JCR16_12095	COG0446	pyridine nucleotide-disulphide oxidoreductase
JCR16_12105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JCR16_12125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JCR16_12135	COG0789	Transcriptional regulator
JCR16_12155	COG1116	anion transmembrane transporter activity
JCR16_12160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JCR16_12170	COG0864	Transcriptional regulator
JCR16_12190	COG2249	NAD(P)H dehydrogenase (quinone) activity
JCR16_12195	COG0439	Biotin carboxylase
JCR16_12210	COG1063	alcohol dehydrogenase
JCR16_12220	COG1309	transcriptional regulator
JCR16_12240	COG0038	chloride channel
JCR16_12245	COG4770	biotin carboxylase activity
JCR16_12265	COG1914	H( )-stimulated, divalent metal cation uptake system
JCR16_12270	COG0583	DNA-binding transcription factor activity
JCR16_12320	COG1250	3-hydroxyacyl-CoA dehydrogenase
JCR16_12340	COG2814	Major facilitator Superfamily
JCR16_12350	COG1560	Kdo2-lipid A biosynthetic process
JCR16_12360	COG5006	permease, DMT superfamily
JCR16_12365	COG1522	sequence-specific DNA binding
JCR16_12380	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JCR16_12390	COG4122	O-methyltransferase activity
JCR16_12420	COG1538	Outer membrane efflux protein
JCR16_12425	COG1137	ATPase activity
JCR16_12430	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
JCR16_12440	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
JCR16_12445	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JCR16_12445	COG0517	IMP dehydrogenase activity
JCR16_12485	COG2814	Major facilitator Superfamily
JCR16_12520	COG1278	Cold shock
JCR16_12525	COG1280	lysine exporter protein (LysE YggA)
JCR16_12555	COG1570	exodeoxyribonuclease VII activity
JCR16_12605	COG0583	DNA-binding transcription factor activity
JCR16_12610	COG4638	Rieske (2fe-2S)
JCR16_12615	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
JCR16_12620	COG0633	Ferredoxin
JCR16_12620	COG0543	2 iron, 2 sulfur cluster binding
JCR16_12625	COG1028	Short-chain dehydrogenase reductase Sdr
JCR16_12630	COG3135	benzoate transporter
JCR16_12635	COG2814	Major facilitator Superfamily
JCR16_12650	COG1643	Atp-dependent helicase
JCR16_12655	COG0450	alkyl hydroperoxide reductase
JCR16_12665	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JCR16_12675	COG3634	alkyl hydroperoxide reductase activity
JCR16_12695	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JCR16_12700	COG0625	glutathione transferase activity
JCR16_12710	COG2885	chlorophyll binding
JCR16_12745	COG0542	response to heat
JCR16_12760	COG1765	OsmC-like protein
JCR16_12780	COG0667	Aldo Keto reductase
JCR16_12795	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JCR16_12805	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JCR16_12815	COG0527	aspartate kinase activity
JCR16_12825	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JCR16_12835	COG3038	cytochrome b561
JCR16_12840	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JCR16_12845	COG2252	PERMEase
JCR16_12855	COG2072	flavoprotein involved in K transport
JCR16_12870	COG1741	Belongs to the pirin family
JCR16_12875	COG1309	transcriptional regulator
JCR16_12885	COG0300	oxidoreductase activity
JCR16_12935	COG4269	membrane
JCR16_12950	COG0446	pyridine nucleotide-disulphide oxidoreductase
JCR16_12950	COG1902	pentaerythritol trinitrate reductase activity
JCR16_12960	COG5001	Diguanylate cyclase
JCR16_12960	COG4251	negative regulation of phosphorylation
JCR16_12960	COG3706	GGDEF domain
JCR16_12960	COG2203	Gaf domain
JCR16_12970	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JCR16_12990	COG4172	Belongs to the ABC transporter superfamily
JCR16_12995	COG4239	(ABC) transporter, permease
JCR16_13000	COG4174	ABC transporter (Permease)
JCR16_13010	COG1388	LysM domain
JCR16_13010	COG0741	lytic transglycosylase activity
JCR16_13010	COG0741	lytic transglycosylase activity
JCR16_13010	COG1388	LysM domain
JCR16_13015	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JCR16_13055	COG0583	DNA-binding transcription factor activity
JCR16_13060	COG1279	arginine transmembrane transporter activity
JCR16_13080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JCR16_13085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JCR16_13090	COG0006	proline dipeptidase activity
JCR16_13130	COG2194	sulfuric ester hydrolase activity
JCR16_13180	COG0739	heme binding
JCR16_13505	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JCR16_13530	COG3384	dioxygenase
JCR16_13540	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JCR16_13545	COG2878	Part of a membrane complex involved in electron transport
JCR16_13550	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JCR16_13575	COG0768	penicillin binding
JCR16_13580	COG0742	ribosomal rna small subunit methyltransferase
JCR16_13595	COG0830	nickel cation binding
JCR16_13640	COG1253	flavin adenine dinucleotide binding
JCR16_13645	COG2851	Citrate transporter
JCR16_13695	COG1773	rubredoxin
JCR16_13700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JCR16_13710	COG0583	DNA-binding transcription factor activity
JCR16_13735	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
JCR16_13740	COG4181	ATPase activity
JCR16_13785	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JCR16_13805	COG0306	phosphate transporter
JCR16_13815	COG3958	Transketolase
JCR16_13820	COG3959	Transketolase, thiamine diphosphate binding domain
JCR16_13825	COG2271	Major facilitator Superfamily
JCR16_13830	COG1028	Short-chain dehydrogenase reductase Sdr
JCR16_13835	COG0583	DNA-binding transcription factor activity
JCR16_13850	COG2223	nitrite transmembrane transporter activity
JCR16_13855	COG2207	Transcriptional regulator
JCR16_13860	COG2066	Belongs to the glutaminase family
JCR16_13865	COG0242	peptide deformylase activity
JCR16_13870	COG0477	Major facilitator Superfamily
JCR16_13880	COG0028	Belongs to the TPP enzyme family
JCR16_13895	COG1028	Short-chain dehydrogenase reductase Sdr
JCR16_13900	COG2267	carboxylic ester hydrolase activity
JCR16_13910	COG2271	Major facilitator Superfamily
JCR16_13915	COG0446	pyridine nucleotide-disulphide oxidoreductase
JCR16_13925	COG1028	Short-chain dehydrogenase reductase Sdr
JCR16_13945	COG1414	Transcriptional regulator
JCR16_13960	COG1024	Enoyl-CoA hydratase
JCR16_13970	COG1215	transferase activity, transferring glycosyl groups
JCR16_13975	COG1649	PFAM Uncharacterised BCR, COG1649
JCR16_13975	COG0726	polysaccharide deacetylase
JCR16_13985	COG4681	YaeQ
JCR16_13995	COG0523	cobalamin synthesis protein
JCR16_14005	COG1607	acyl-coa hydrolase
JCR16_14015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JCR16_14020	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JCR16_14025	COG1309	transcriptional regulator
JCR16_14050	COG2040	homocysteine
JCR16_14055	COG0531	amino acid
JCR16_14110	COG1595	DNA-templated transcription, initiation
JCR16_14120	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JCR16_14125	COG0477	Major facilitator Superfamily
JCR16_14255	COG0592	DNA-directed DNA polymerase activity
JCR16_14295	COG2026	Addiction module toxin, RelE StbE family
JCR16_14500	COG1484	DNA-dependent DNA replication
JCR16_14565	COG3620	sequence-specific DNA binding
JCR16_14665	COG0405	Gamma-glutamyltransferase
JCR16_14670	COG2814	Major facilitator Superfamily
JCR16_14680	COG2050	protein possibly involved in aromatic compounds catabolism
JCR16_14695	COG1090	epimerase
JCR16_14715	COG0420	3'-5' exonuclease activity
JCR16_14740	COG0735	belongs to the Fur family
JCR16_14745	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JCR16_14765	COG0121	glutamine amidotransferase
JCR16_14780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JCR16_14790	COG0210	DNA helicase
JCR16_14795	COG2885	chlorophyll binding
JCR16_14800	COG0204	Acyl-transferase
JCR16_14815	COG2894	cell division
JCR16_14840	COG1280	lysine exporter protein (LysE YggA)
JCR16_14845	COG1674	ftsk spoiiie
JCR16_14845	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JCR16_14850	COG0492	ferredoxin-NADP+ reductase activity
JCR16_14855	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
JCR16_14865	COG0456	acetyltransferase
JCR16_14915	COG1981	membrane
JCR16_14930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JCR16_14930	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JCR16_14950	COG1012	belongs to the aldehyde dehydrogenase family
JCR16_14960	COG0657	acetylesterase activity
JCR16_14970	COG0473	3-isopropylmalate dehydrogenase activity
JCR16_14975	COG0583	DNA-binding transcription factor activity
JCR16_14995	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JCR16_15020	COG0564	pseudouridine synthase activity
JCR16_15030	COG0358	DNA primase activity
JCR16_15045	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
JCR16_15075	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JCR16_15105	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JCR16_15115	COG0352	thiamine-phosphate diphosphorylase activity
JCR16_15115	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JCR16_15115	COG0351	phosphomethylpyrimidine kinase
JCR16_15120	COG1652	LysM domain
JCR16_15145	COG1399	metal-binding, possibly nucleic acid-binding protein
JCR16_15150	COG3101	peptidyl-lysine hydroxylation
JCR16_15155	COG0009	L-threonylcarbamoyladenylate synthase
JCR16_15160	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JCR16_15165	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JCR16_15180	COG4106	trans-aconitate 2-methyltransferase activity
JCR16_15195	COG0596	Alpha beta hydrolase
JCR16_15195	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JCR16_15195	COG2226	methyltransferase
JCR16_15200	COG1877	trehalose-phosphatase activity
JCR16_15205	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
JCR16_15210	COG2223	nitrite transmembrane transporter activity
JCR16_15230	COG1196	nuclear chromosome segregation
JCR16_15240	COG0730	response to heat
JCR16_15255	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JCR16_15265	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JCR16_15315	COG0489	protein tyrosine kinase activity
JCR16_15325	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JCR16_15325	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JCR16_15355	COG2515	1-aminocyclopropane-1-carboxylate deaminase
JCR16_15360	COG2081	HI0933 family
JCR16_15370	COG0668	transmembrane transport
JCR16_15390	COG0583	DNA-binding transcription factor activity
JCR16_15410	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JCR16_15415	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JCR16_15445	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
JCR16_15485	COG0745	RESPONSE REGULATOR receiver
JCR16_15505	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JCR16_15515	COG2205	protein histidine kinase activity
JCR16_15595	COG4993	Dehydrogenase
JCR16_15625	COG0384	phenazine biosynthesis protein PhzF
JCR16_15650	COG1061	Type III restriction enzyme res subunit
JCR16_15660	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JCR16_15665	COG1192	Involved in chromosome partitioning
JCR16_15695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JCR16_15710	COG0583	DNA-binding transcription factor activity
JCR16_15740	COG0583	DNA-binding transcription factor activity
JCR16_15755	COG0583	DNA-binding transcription factor activity
JCR16_15760	COG1053	succinate dehydrogenase
JCR16_15770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JCR16_15775	COG2814	Major facilitator Superfamily
JCR16_15780	COG1960	acyl-CoA dehydrogenase activity
JCR16_15785	COG0583	DNA-binding transcription factor activity
JCR16_15790	COG1063	alcohol dehydrogenase
JCR16_15820	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JCR16_15825	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JCR16_15830	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JCR16_15845	COG3667	copper resistance
JCR16_15850	COG2132	Multicopper oxidase
JCR16_15860	COG0561	phosphatase activity
JCR16_15865	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JCR16_15890	COG1214	PFAM Peptidase M22, glycoprotease
JCR16_15940	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JCR16_15950	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JCR16_15955	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JCR16_15960	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JCR16_16020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JCR16_16030	COG1846	Transcriptional regulator
JCR16_16035	COG1764	response to oxidative stress
JCR16_16075	COG0037	tRNA processing
JCR16_16085	COG0248	Ppx GppA phosphatase
JCR16_16115	COG0072	phenylalanine-tRNA ligase activity
JCR16_16155	COG1238	metal cluster binding
JCR16_16160	COG0625	glutathione transferase activity
JCR16_16175	COG0318	PFAM AMP-dependent synthetase and ligase
JCR16_16180	COG3028	Belongs to the UPF0307 family
JCR16_16185	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JCR16_16205	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JCR16_16210	COG0617	tRNA 3'-terminal CCA addition
JCR16_16215	COG1555	photosystem II stabilization
JCR16_16220	COG3956	TIGRFAM MazG family protein
JCR16_16230	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JCR16_16250	COG2205	protein histidine kinase activity
JCR16_16250	COG5002	protein histidine kinase activity
JCR16_16250	COG0784	Response regulator, receiver
JCR16_16255	COG1024	Enoyl-CoA hydratase
JCR16_16260	COG2084	Dehydrogenase
JCR16_16265	COG3622	Belongs to the hyi family
JCR16_16295	COG0697	spore germination
JCR16_16305	COG2814	Major facilitator Superfamily
JCR16_16310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JCR16_16320	COG0583	DNA-binding transcription factor activity
JCR16_16330	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JCR16_16345	COG0084	hydrolase, TatD family'
JCR16_16360	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JCR16_16390	COG0440	acetolactate synthase activity
JCR16_16395	COG0028	Belongs to the TPP enzyme family
JCR16_16420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JCR16_16425	COG1136	(ABC) transporter
JCR16_16425	COG0577	efflux transmembrane transporter activity
JCR16_16430	COG1538	Outer membrane efflux protein
JCR16_16445	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
JCR16_16450	COG1162	GTPase activity
JCR16_16460	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JCR16_16480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JCR16_16485	COG1028	Short-chain dehydrogenase reductase Sdr
JCR16_16525	COG2986	histidine ammonia-lyase
JCR16_16540	COG0318	PFAM AMP-dependent synthetase and ligase
JCR16_16550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JCR16_16595	COG1426	Protein conserved in bacteria
JCR16_16630	COG0793	Belongs to the peptidase S41A family
JCR16_16645	COG2267	carboxylic ester hydrolase activity
JCR16_16655	COG1012	belongs to the aldehyde dehydrogenase family
JCR16_16660	COG3265	gluconokinase activity
JCR16_16670	COG0800	Aldolase
JCR16_16685	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JCR16_16690	COG0857	belongs to the CobB CobQ family
JCR16_16690	COG0280	phosphate acetyltransferase
JCR16_16695	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
JCR16_16695	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
JCR16_16715	COG0740	serine-type endopeptidase activity
JCR16_16725	COG4774	siderophore transport
JCR16_16735	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JCR16_16745	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JCR16_16745	COG2813	Specifically methylates the guanine in position
JCR16_16845	COG0788	formyltetrahydrofolate deformylase activity
JCR16_16870	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JCR16_16870	COG4651	solute:proton antiporter activity
JCR16_16890	COG0724	RNA recognition motif
JCR16_16895	COG0210	DNA helicase
JCR16_16920	COG1733	regulation of RNA biosynthetic process
JCR16_16930	COG2900	Belongs to the SlyX family
JCR16_16935	COG0488	(ABC) transporter
JCR16_16940	COG1280	lysine exporter protein (LysE YggA)
JCR16_16945	COG1560	Kdo2-lipid A biosynthetic process
JCR16_16955	COG1301	dicarboxylic acid transport
JCR16_17010	COG0473	3-isopropylmalate dehydrogenase activity
JCR16_17075	COG1192	Involved in chromosome partitioning
JCR16_17080	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JCR16_17090	COG1061	Type III restriction enzyme res subunit
JCR16_17125	COG0583	DNA-binding transcription factor activity
JCR16_17135	COG0625	glutathione transferase activity
JCR16_17140	COG2378	regulation of single-species biofilm formation
JCR16_17145	COG0546	phosphoglycolate phosphatase activity
JCR16_17155	COG1530	ribonuclease E activity
JCR16_17160	COG0318	PFAM AMP-dependent synthetase and ligase
JCR16_17175	COG0583	DNA-binding transcription factor activity
JCR16_17180	COG4221	oxidoreductase activity
JCR16_17185	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JCR16_17195	COG0534	Mate efflux family protein
JCR16_17210	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JCR16_17250	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
JCR16_17255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JCR16_17270	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JCR16_17280	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
JCR16_17280	COG0644	oxidoreductase
JCR16_17285	COG0425	Belongs to the sulfur carrier protein TusA family
JCR16_17290	COG4535	Mg2 and Co2 transporter CorC
JCR16_17300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JCR16_17320	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JCR16_17325	COG0475	glutathione-regulated potassium exporter activity
JCR16_17325	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JCR16_17330	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JCR16_17340	COG0484	heat shock protein binding
JCR16_17345	COG0789	Transcriptional regulator
JCR16_17350	COG0598	Magnesium transport protein CorA
JCR16_17365	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JCR16_17370	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JCR16_17375	COG1074	ATP-dependent DNA helicase activity
JCR16_17380	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JCR16_17400	COG2226	methyltransferase
JCR16_17415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JCR16_17420	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JCR16_17435	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JCR16_17435	COG2111	Na H antiporter
JCR16_17440	COG1006	Multisubunit Na H antiporter MnhC subunit
JCR16_17445	COG0651	ATP synthesis coupled electron transport
JCR16_17450	COG1863	multisubunit Na H antiporter MnhE subunit
JCR16_17455	COG2212	antiporter activity
JCR16_17460	COG1320	monovalent cation:proton antiporter activity
JCR16_17475	COG0195	Participates in both transcription termination and antitermination
JCR16_17525	COG0237	dephospho-CoA kinase activity
JCR16_17535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JCR16_17550	COG0497	DNA recombination
JCR16_17560	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JCR16_17590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JCR16_17590	COG2169	Transcriptional regulator
JCR16_17595	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JCR16_17660	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JCR16_17675	COG0326	Molecular chaperone. Has ATPase activity
JCR16_17690	COG2056	Na+-H+ antiporter family
JCR16_17695	COG0596	Alpha beta hydrolase
JCR16_17790	COG0546	phosphoglycolate phosphatase activity
JCR16_17795	COG1716	ATPase activity
JCR16_17840	COG0181	hydroxymethylbilane synthase activity
JCR16_17850	COG3275	phosphorelay sensor kinase activity
JCR16_17870	COG1538	Outer membrane efflux protein
JCR16_17875	COG0697	spore germination
JCR16_17900	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JCR16_17905	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JCR16_17910	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JCR16_17915	COG0772	Belongs to the SEDS family
JCR16_17940	COG4974	Belongs to the 'phage' integrase family
JCR16_17945	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JCR16_17955	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JCR16_17965	COG2197	response regulator
JCR16_17980	COG0793	Belongs to the peptidase S41A family
JCR16_17985	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JCR16_17990	COG0795	lipopolysaccharide-transporting ATPase activity
JCR16_18030	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JCR16_18030	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JCR16_18040	COG0004	ammonium transporteR
JCR16_18045	COG0347	Belongs to the P(II) protein family
JCR16_18055	COG0606	chelatase, subunit chli
JCR16_18065	COG0659	secondary active sulfate transmembrane transporter activity
JCR16_18070	COG0589	response to stress
JCR16_18100	COG0606	chelatase, subunit chli
JCR16_18105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JCR16_18115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JCR16_18130	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JCR16_18145	COG0318	PFAM AMP-dependent synthetase and ligase
JCR16_18155	COG0477	Major facilitator Superfamily
JCR16_18160	COG2860	membrane
JCR16_18170	COG1253	flavin adenine dinucleotide binding
JCR16_18190	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JCR16_18225	COG0655	NAD(P)H dehydrogenase (quinone) activity
JCR16_18235	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JCR16_18270	COG1309	transcriptional regulator
JCR16_18305	COG0758	DNA mediated transformation
JCR16_18315	COG0697	spore germination
JCR16_18320	COG1309	transcriptional regulator
JCR16_18335	COG0386	Belongs to the glutathione peroxidase family
JCR16_18400	COG1121	(ABC) transporter
JCR16_18405	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JCR16_18410	COG1280	lysine exporter protein (LysE YggA)
JCR16_18415	COG2837	iron assimilation
JCR16_18420	COG0281	malic enzyme
JCR16_18465	COG0519	Catalyzes the synthesis of GMP from XMP
JCR16_18465	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JCR16_18470	COG4399	Belongs to the UPF0754 family
JCR16_18475	COG2259	Doxx family
JCR16_18480	COG0586	Pfam SNARE associated Golgi protein
JCR16_18495	COG1192	Involved in chromosome partitioning
JCR16_18505	COG0271	Belongs to the BolA IbaG family
JCR16_18545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JCR16_18545	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JCR16_18545	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
JCR16_18545	COG3321	synthase
JCR16_18550	COG1960	acyl-CoA dehydrogenase activity
JCR16_18565	COG2197	response regulator
JCR16_18575	COG3916	Acyl-homoserine-lactone synthase
JCR16_18580	COG0477	Major facilitator Superfamily
JCR16_18585	COG1024	Enoyl-CoA hydratase
JCR16_18590	COG1024	Enoyl-CoA hydratase
JCR16_18595	COG1960	acyl-CoA dehydrogenase activity
JCR16_18600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JCR16_18620	COG1113	amino acid transport
JCR16_18625	COG1113	amino acid transport
JCR16_18630	COG0251	oxidation-reduction process
JCR16_18670	COG0564	pseudouridine synthase activity
JCR16_18735	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JCR16_18750	COG1802	Transcriptional regulator
JCR16_18760	COG1448	Aminotransferase
JCR16_18765	COG0277	FAD linked oxidase domain protein
JCR16_18775	COG2186	Transcriptional regulator
JCR16_18785	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JCR16_18790	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JCR16_18805	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JCR16_18810	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JCR16_18815	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JCR16_18875	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JCR16_18880	COG1596	polysaccharide export
JCR16_18905	COG0728	peptidoglycan biosynthetic process
JCR16_18910	COG3023	N-Acetylmuramoyl-L-alanine amidase
JCR16_18965	COG0546	phosphoglycolate phosphatase activity
JCR16_18970	COG1028	Short-chain dehydrogenase reductase Sdr
JCR16_18990	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JCR16_18995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JCR16_19000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JCR16_19005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JCR16_19010	COG1116	anion transmembrane transporter activity
JCR16_19015	COG1309	transcriptional regulator
JCR16_19020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JCR16_19030	COG0196	riboflavin kinase activity
JCR16_19035	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JCR16_19045	COG1047	Peptidyl-prolyl cis-trans
JCR16_19085	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JCR16_19090	COG0657	acetylesterase activity
JCR16_19140	COG2951	lytic endotransglycosylase activity
JCR16_19145	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JCR16_19160	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JCR16_19170	COG0671	phosphoesterase, PA-phosphatase related
JCR16_19175	COG0861	Integral membrane protein TerC family
JCR16_19185	COG0754	glutathionylspermidine amidase activity
JCR16_19195	COG0402	S-adenosylhomocysteine deaminase activity
JCR16_19210	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JCR16_19215	COG1230	cation diffusion facilitator family transporter
JCR16_19230	COG0706	membrane insertase activity
JCR16_19395	COG1525	nuclease
JCR16_19465	COG1475	DNA binding
JCR16_19485	COG3853	Toxic anion resistance protein (TelA)
JCR16_19580	COG0484	heat shock protein binding
JCR16_19670	COG0741	lytic transglycosylase activity
JCR16_19705	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JCR16_19765	COG1047	Peptidyl-prolyl cis-trans