locus-tag	class	description
FK728_00001	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FK728_00002	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FK728_00003	COG0596	Alpha beta hydrolase
FK728_00008	COG0488	(ABC) transporter
FK728_00009	COG0586	Pfam SNARE associated Golgi protein
FK728_00011	COG0187	DNA topoisomerase II activity
FK728_00013	COG0592	DNA-directed DNA polymerase activity
FK728_00015	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FK728_00018	COG0706	membrane insertase activity
FK728_00021	COG1230	cation diffusion facilitator family transporter
FK728_00022	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FK728_00026	COG0402	S-adenosylhomocysteine deaminase activity
FK728_00028	COG0754	glutathionylspermidine amidase activity
FK728_00030	COG0861	Integral membrane protein TerC family
FK728_00031	COG0671	phosphoesterase, PA-phosphatase related
FK728_00033	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FK728_00036	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FK728_00037	COG2951	lytic endotransglycosylase activity
FK728_00043	COG0583	DNA-binding transcription factor activity
FK728_00048	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FK728_00056	COG1047	Peptidyl-prolyl cis-trans
FK728_00058	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FK728_00059	COG0196	riboflavin kinase activity
FK728_00061	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FK728_00062	COG1309	transcriptional regulator
FK728_00063	COG1116	anion transmembrane transporter activity
FK728_00064	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FK728_00065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FK728_00066	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FK728_00067	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FK728_00071	COG1028	Short-chain dehydrogenase reductase Sdr
FK728_00072	COG0546	phosphoglycolate phosphatase activity
FK728_00083	COG3023	N-Acetylmuramoyl-L-alanine amidase
FK728_00084	COG0728	peptidoglycan biosynthetic process
FK728_00090	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FK728_00092	COG1091	dTDP-4-dehydrorhamnose reductase activity
FK728_00093	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FK728_00095	COG2244	polysaccharide biosynthetic process
FK728_00098	COG0438	transferase activity, transferring glycosyl groups
FK728_00099	COG0463	Glycosyl transferase, family 2
FK728_00100	COG0110	maltose O-acetyltransferase activity
FK728_00103	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FK728_00104	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FK728_00108	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FK728_00110	COG2186	Transcriptional regulator
FK728_00112	COG0277	FAD linked oxidase domain protein
FK728_00113	COG1448	Aminotransferase
FK728_00114	COG1802	Transcriptional regulator
FK728_00117	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FK728_00124	COG2801	Transposase and inactivated derivatives
FK728_00134	COG0564	pseudouridine synthase activity
FK728_00139	COG1522	sequence-specific DNA binding
FK728_00142	COG0251	oxidation-reduction process
FK728_00143	COG1113	amino acid transport
FK728_00144	COG1113	amino acid transport
FK728_00148	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FK728_00149	COG1960	acyl-CoA dehydrogenase activity
FK728_00150	COG1024	Enoyl-CoA hydratase
FK728_00151	COG1024	Enoyl-CoA hydratase
FK728_00152	COG0477	Major facilitator Superfamily
FK728_00153	COG3916	Acyl-homoserine-lactone synthase
FK728_00155	COG2197	response regulator
FK728_00157	COG1960	acyl-CoA dehydrogenase activity
FK728_00158	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FK728_00158	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FK728_00158	COG3321	synthase
FK728_00158	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FK728_00162	COG2267	carboxylic ester hydrolase activity
FK728_00166	COG0271	Belongs to the BolA IbaG family
FK728_00168	COG1192	Involved in chromosome partitioning
FK728_00171	COG0586	Pfam SNARE associated Golgi protein
FK728_00172	COG2259	Doxx family
FK728_00173	COG4399	Belongs to the UPF0754 family
FK728_00174	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FK728_00174	COG0519	Catalyzes the synthesis of GMP from XMP
FK728_00183	COG0281	malic enzyme
FK728_00184	COG2837	iron assimilation
FK728_00185	COG1280	lysine exporter protein (LysE YggA)
FK728_00186	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FK728_00187	COG1121	(ABC) transporter
FK728_00200	COG0386	Belongs to the glutathione peroxidase family
FK728_00203	COG1309	transcriptional regulator
FK728_00204	COG0697	spore germination
FK728_00206	COG0758	DNA mediated transformation
FK728_00214	COG4771	TonB-dependent receptor
FK728_00217	COG1309	transcriptional regulator
FK728_00224	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FK728_00227	COG0655	NAD(P)H dehydrogenase (quinone) activity
FK728_00234	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FK728_00236	COG0477	Major facilitator Superfamily
FK728_00238	COG1253	flavin adenine dinucleotide binding
FK728_00240	COG2860	membrane
FK728_00241	COG0477	Major facilitator Superfamily
FK728_00243	COG0318	PFAM AMP-dependent synthetase and ligase
FK728_00246	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FK728_00250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FK728_00251	COG0235	Class ii aldolase
FK728_00252	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FK728_00262	COG2217	Heavy metal translocating P-type atpase
FK728_00263	COG2205	protein histidine kinase activity
FK728_00266	COG2132	Multicopper oxidase
FK728_00271	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FK728_00280	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FK728_00290	COG0347	Belongs to the P(II) protein family
FK728_00291	COG0004	ammonium transporteR
FK728_00293	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FK728_00293	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FK728_00301	COG0795	lipopolysaccharide-transporting ATPase activity
FK728_00302	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FK728_00303	COG0793	Belongs to the peptidase S41A family
FK728_00306	COG2197	response regulator
FK728_00308	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FK728_00310	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FK728_00311	COG4974	Belongs to the 'phage' integrase family
FK728_00316	COG0772	Belongs to the SEDS family
FK728_00317	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FK728_00318	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FK728_00319	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FK728_00324	COG0697	spore germination
FK728_00325	COG1538	Outer membrane efflux protein
FK728_00329	COG3275	phosphorelay sensor kinase activity
FK728_00331	COG0181	hydroxymethylbilane synthase activity
FK728_00340	COG1716	ATPase activity
FK728_00341	COG0546	phosphoglycolate phosphatase activity
FK728_00361	COG2056	Na+-H+ antiporter family
FK728_00364	COG0326	Molecular chaperone. Has ATPase activity
FK728_00367	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FK728_00380	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FK728_00381	COG2169	Transcriptional regulator
FK728_00381	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FK728_00387	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FK728_00389	COG0497	DNA recombination
FK728_00392	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FK728_00394	COG0237	dephospho-CoA kinase activity
FK728_00404	COG0195	Participates in both transcription termination and antitermination
FK728_00408	COG2212	antiporter activity
FK728_00410	COG0651	ATP synthesis coupled electron transport
FK728_00411	COG1006	Multisubunit Na H antiporter MnhC subunit
FK728_00412	COG2111	Na H antiporter
FK728_00412	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FK728_00415	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FK728_00418	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FK728_00421	COG2226	methyltransferase
FK728_00425	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FK728_00426	COG1074	ATP-dependent DNA helicase activity
FK728_00427	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FK728_00431	COG0598	Magnesium transport protein CorA
FK728_00432	COG0789	Transcriptional regulator
FK728_00433	COG0484	heat shock protein binding
FK728_00436	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FK728_00436	COG0475	glutathione-regulated potassium exporter activity
FK728_00437	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FK728_00441	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FK728_00443	COG4535	Mg2 and Co2 transporter CorC
FK728_00444	COG0425	Belongs to the sulfur carrier protein TusA family
FK728_00446	COG0644	oxidoreductase
FK728_00446	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FK728_00448	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FK728_00451	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FK728_00452	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FK728_00459	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FK728_00462	COG0534	Mate efflux family protein
FK728_00464	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FK728_00465	COG4221	oxidoreductase activity
FK728_00466	COG0583	DNA-binding transcription factor activity
FK728_00470	COG1530	ribonuclease E activity
FK728_00472	COG0546	phosphoglycolate phosphatase activity
FK728_00473	COG2378	regulation of single-species biofilm formation
FK728_00474	COG0625	glutathione transferase activity
FK728_00476	COG0583	DNA-binding transcription factor activity
FK728_00487	COG0473	3-isopropylmalate dehydrogenase activity
FK728_00498	COG1301	dicarboxylic acid transport
FK728_00500	COG1560	Kdo2-lipid A biosynthetic process
FK728_00501	COG1280	lysine exporter protein (LysE YggA)
FK728_00506	COG1733	regulation of RNA biosynthetic process
FK728_00511	COG0210	DNA helicase
FK728_00512	COG0724	RNA recognition motif
FK728_00516	COG4651	solute:proton antiporter activity
FK728_00516	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FK728_00517	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FK728_00518	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FK728_00521	COG0788	formyltetrahydrofolate deformylase activity
FK728_00541	COG2813	Specifically methylates the guanine in position
FK728_00541	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FK728_00543	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FK728_00545	COG4774	siderophore transport
FK728_00547	COG0740	serine-type endopeptidase activity
FK728_00551	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FK728_00551	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FK728_00552	COG0280	phosphate acetyltransferase
FK728_00552	COG0857	belongs to the CobB CobQ family
FK728_00553	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FK728_00555	COG0800	Aldolase
FK728_00557	COG3265	gluconokinase activity
FK728_00558	COG1012	belongs to the aldehyde dehydrogenase family
FK728_00560	COG2267	carboxylic ester hydrolase activity
FK728_00563	COG0793	Belongs to the peptidase S41A family
FK728_00570	COG1426	Protein conserved in bacteria
FK728_00578	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FK728_00580	COG1162	GTPase activity
FK728_00581	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FK728_00584	COG1538	Outer membrane efflux protein
FK728_00585	COG1136	(ABC) transporter
FK728_00585	COG0577	efflux transmembrane transporter activity
FK728_00586	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FK728_00591	COG0028	Belongs to the TPP enzyme family
FK728_00592	COG0440	acetolactate synthase activity
FK728_00598	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FK728_00601	COG0084	hydrolase, TatD family'
FK728_00604	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FK728_00605	COG0583	DNA-binding transcription factor activity
FK728_00607	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FK728_00608	COG2814	Major facilitator Superfamily
FK728_00610	COG0697	spore germination
FK728_00611	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FK728_00612	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FK728_00613	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FK728_00616	COG3622	Belongs to the hyi family
FK728_00617	COG2084	Dehydrogenase
FK728_00618	COG1024	Enoyl-CoA hydratase
FK728_00619	COG0784	Response regulator, receiver
FK728_00619	COG2205	protein histidine kinase activity
FK728_00619	COG5002	protein histidine kinase activity
FK728_00623	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FK728_00625	COG3956	TIGRFAM MazG family protein
FK728_00626	COG1555	photosystem II stabilization
FK728_00627	COG0617	tRNA 3'-terminal CCA addition
FK728_00628	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FK728_00632	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FK728_00633	COG3028	Belongs to the UPF0307 family
FK728_00634	COG0318	PFAM AMP-dependent synthetase and ligase
FK728_00637	COG0625	glutathione transferase activity
FK728_00638	COG1238	metal cluster binding
FK728_00641	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FK728_00646	COG0072	phenylalanine-tRNA ligase activity
FK728_00651	COG0248	Ppx GppA phosphatase
FK728_00653	COG0037	tRNA processing
FK728_00661	COG1764	response to oxidative stress
FK728_00662	COG1846	Transcriptional regulator
FK728_00664	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FK728_00676	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FK728_00677	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FK728_00678	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FK728_00690	COG1214	PFAM Peptidase M22, glycoprotease
FK728_00695	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FK728_00696	COG0561	phosphatase activity
FK728_00698	COG2132	Multicopper oxidase
FK728_00702	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FK728_00703	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FK728_00704	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FK728_00710	COG1063	alcohol dehydrogenase
FK728_00711	COG0583	DNA-binding transcription factor activity
FK728_00712	COG1960	acyl-CoA dehydrogenase activity
FK728_00713	COG2814	Major facilitator Superfamily
FK728_00714	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FK728_00716	COG1053	succinate dehydrogenase
FK728_00717	COG0583	DNA-binding transcription factor activity
FK728_00720	COG0583	DNA-binding transcription factor activity
FK728_00722	COG1473	amidohydrolase
FK728_00726	COG0583	DNA-binding transcription factor activity
FK728_00728	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FK728_00729	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FK728_00744	COG0210	DNA helicase
FK728_00757	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FK728_00760	COG0745	RESPONSE REGULATOR receiver
FK728_00761	COG2205	protein histidine kinase activity
FK728_00768	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FK728_00774	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FK728_00775	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FK728_00780	COG0583	DNA-binding transcription factor activity
FK728_00784	COG0668	transmembrane transport
FK728_00786	COG2081	HI0933 family
FK728_00787	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FK728_00793	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FK728_00793	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FK728_00795	COG0489	protein tyrosine kinase activity
FK728_00806	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FK728_00808	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FK728_00811	COG0730	response to heat
FK728_00813	COG1196	nuclear chromosome segregation
FK728_00817	COG2223	nitrite transmembrane transporter activity
FK728_00818	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FK728_00819	COG1877	trehalose-phosphatase activity
FK728_00820	COG0596	Alpha beta hydrolase
FK728_00820	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FK728_00820	COG2226	methyltransferase
FK728_00823	COG4106	trans-aconitate 2-methyltransferase activity
FK728_00826	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FK728_00827	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FK728_00828	COG0009	L-threonylcarbamoyladenylate synthase
FK728_00829	COG3101	peptidyl-lysine hydroxylation
FK728_00830	COG1399	metal-binding, possibly nucleic acid-binding protein
FK728_00835	COG1652	LysM domain
FK728_00836	COG0351	phosphomethylpyrimidine kinase
FK728_00836	COG0352	thiamine-phosphate diphosphorylase activity
FK728_00836	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FK728_00838	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FK728_00844	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FK728_00849	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FK728_00852	COG0358	DNA primase activity
FK728_00854	COG0564	pseudouridine synthase activity
FK728_00859	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FK728_00862	COG0583	DNA-binding transcription factor activity
FK728_00863	COG0473	3-isopropylmalate dehydrogenase activity
FK728_00867	COG1012	belongs to the aldehyde dehydrogenase family
FK728_00871	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FK728_00871	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FK728_00883	COG0456	acetyltransferase
FK728_00885	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FK728_00886	COG0492	ferredoxin-NADP+ reductase activity
FK728_00887	COG1674	ftsk spoiiie
FK728_00887	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FK728_00888	COG1280	lysine exporter protein (LysE YggA)
FK728_00891	COG2894	cell division
FK728_00894	COG0204	Acyl-transferase
FK728_00895	COG2885	chlorophyll binding
FK728_00896	COG0210	DNA helicase
FK728_00898	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FK728_00901	COG0121	glutamine amidotransferase
FK728_00905	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FK728_00906	COG0735	belongs to the Fur family
FK728_00911	COG0420	3'-5' exonuclease activity
FK728_00915	COG1090	epimerase
FK728_00918	COG2050	protein possibly involved in aromatic compounds catabolism
FK728_00919	COG1566	PFAM secretion protein HlyD family protein
FK728_00920	COG2814	Major facilitator Superfamily
FK728_00921	COG0405	Gamma-glutamyltransferase
FK728_00934	COG0477	Major facilitator Superfamily
FK728_00935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FK728_00940	COG0531	amino acid
FK728_00941	COG2040	homocysteine
FK728_00946	COG1309	transcriptional regulator
FK728_00947	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FK728_00948	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FK728_00950	COG1607	acyl-coa hydrolase
FK728_00952	COG0523	cobalamin synthesis protein
FK728_00954	COG4681	YaeQ
FK728_00956	COG1649	PFAM Uncharacterised BCR, COG1649
FK728_00956	COG0726	polysaccharide deacetylase
FK728_00957	COG1215	transferase activity, transferring glycosyl groups
FK728_00959	COG1024	Enoyl-CoA hydratase
FK728_00962	COG1414	Transcriptional regulator
FK728_00966	COG1028	Short-chain dehydrogenase reductase Sdr
FK728_00969	COG2271	Major facilitator Superfamily
FK728_00971	COG2267	carboxylic ester hydrolase activity
FK728_00972	COG1028	Short-chain dehydrogenase reductase Sdr
FK728_00975	COG0028	Belongs to the TPP enzyme family
FK728_00977	COG0477	Major facilitator Superfamily
FK728_00978	COG0242	peptide deformylase activity
FK728_00979	COG2066	Belongs to the glutaminase family
FK728_00980	COG2207	Transcriptional regulator
FK728_00981	COG2223	nitrite transmembrane transporter activity
FK728_00984	COG0583	DNA-binding transcription factor activity
FK728_00985	COG1028	Short-chain dehydrogenase reductase Sdr
FK728_00986	COG2271	Major facilitator Superfamily
FK728_00987	COG3959	Transketolase, thiamine diphosphate binding domain
FK728_00988	COG3958	Transketolase
FK728_00990	COG0306	phosphate transporter
FK728_00994	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FK728_01003	COG4181	ATPase activity
FK728_01004	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FK728_01009	COG0583	DNA-binding transcription factor activity
FK728_01011	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FK728_01012	COG1773	rubredoxin
FK728_01022	COG2851	Citrate transporter
FK728_01023	COG1253	flavin adenine dinucleotide binding
FK728_01031	COG0804	urea catabolic process
FK728_01033	COG0830	nickel cation binding
FK728_01036	COG0742	ribosomal rna small subunit methyltransferase
FK728_01037	COG0768	penicillin binding
FK728_01041	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FK728_01042	COG2878	Part of a membrane complex involved in electron transport
FK728_01043	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FK728_01045	COG3384	dioxygenase
FK728_01051	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FK728_01105	COG1598	PFAM Uncharacterised protein family UPF0150
FK728_01133	COG0006	proline dipeptidase activity
FK728_01134	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FK728_01135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FK728_01139	COG1279	arginine transmembrane transporter activity
FK728_01140	COG0583	DNA-binding transcription factor activity
FK728_01148	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FK728_01149	COG1388	LysM domain
FK728_01149	COG1388	LysM domain
FK728_01149	COG0741	lytic transglycosylase activity
FK728_01149	COG0741	lytic transglycosylase activity
FK728_01151	COG4174	ABC transporter (Permease)
FK728_01152	COG4239	(ABC) transporter, permease
FK728_01153	COG4172	Belongs to the ABC transporter superfamily
FK728_01158	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FK728_01160	COG2203	Gaf domain
FK728_01160	COG4251	negative regulation of phosphorylation
FK728_01160	COG5001	Diguanylate cyclase
FK728_01160	COG3706	GGDEF domain
FK728_01162	COG0446	pyridine nucleotide-disulphide oxidoreductase
FK728_01162	COG1902	pentaerythritol trinitrate reductase activity
FK728_01164	COG0582	viral genome integration into host DNA
FK728_01185	COG2814	Major facilitator Superfamily
FK728_01189	COG1230	cation diffusion facilitator family transporter
FK728_01192	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FK728_01195	COG2059	Chromate
FK728_01202	COG3501	Rhs element vgr protein
FK728_01203	COG3209	COG3209 Rhs family protein
FK728_01205	COG4372	Transposase
FK728_01207	COG2963	transposase activity
FK728_01210	COG1113	amino acid transport
FK728_01212	COG0531	amino acid
FK728_01216	COG1012	belongs to the aldehyde dehydrogenase family
FK728_01220	COG1113	amino acid transport
FK728_01223	COG0697	spore germination
FK728_01224	COG2721	sulfolactate sulfo-lyase activity
FK728_01225	COG2271	Major facilitator Superfamily
FK728_01226	COG4948	Mandelate Racemase Muconate Lactonizing
FK728_01228	COG1012	belongs to the aldehyde dehydrogenase family
FK728_01229	COG2186	Transcriptional regulator
FK728_01234	COG1960	acyl-CoA dehydrogenase activity
FK728_01236	COG1012	belongs to the aldehyde dehydrogenase family
FK728_01237	COG1024	Enoyl-CoA hydratase
FK728_01238	COG2814	Major facilitator Superfamily
FK728_01241	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FK728_01244	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FK728_01252	COG2207	Transcriptional regulator
FK728_01254	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FK728_01256	COG0583	DNA-binding transcription factor activity
FK728_01257	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FK728_01258	COG2072	flavoprotein involved in K transport
FK728_01259	COG0300	oxidoreductase activity
FK728_01261	COG1309	transcriptional regulator
FK728_01262	COG1741	Belongs to the pirin family
FK728_01265	COG2072	flavoprotein involved in K transport
FK728_01269	COG2252	PERMEase
FK728_01270	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FK728_01271	COG3038	cytochrome b561
FK728_01273	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FK728_01277	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FK728_01279	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FK728_01282	COG0667	Aldo Keto reductase
FK728_01284	COG1765	OsmC-like protein
FK728_01294	COG2885	chlorophyll binding
FK728_01296	COG0625	glutathione transferase activity
FK728_01297	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FK728_01301	COG3634	alkyl hydroperoxide reductase activity
FK728_01303	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FK728_01305	COG0450	alkyl hydroperoxide reductase
FK728_01306	COG1643	Atp-dependent helicase
FK728_01309	COG2814	Major facilitator Superfamily
FK728_01310	COG3135	benzoate transporter
FK728_01311	COG1028	Short-chain dehydrogenase reductase Sdr
FK728_01312	COG0543	2 iron, 2 sulfur cluster binding
FK728_01312	COG0633	Ferredoxin
FK728_01313	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FK728_01314	COG4638	Rieske (2fe-2S)
FK728_01315	COG0583	DNA-binding transcription factor activity
FK728_01325	COG1570	exodeoxyribonuclease VII activity
FK728_01332	COG1280	lysine exporter protein (LysE YggA)
FK728_01333	COG1278	Cold shock
FK728_01340	COG2814	Major facilitator Superfamily
FK728_01341	COG1733	regulation of RNA biosynthetic process
FK728_01346	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FK728_01350	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FK728_01350	COG0517	IMP dehydrogenase activity
FK728_01351	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FK728_01353	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FK728_01354	COG1137	ATPase activity
FK728_01355	COG1538	Outer membrane efflux protein
FK728_01363	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FK728_01366	COG1522	sequence-specific DNA binding
FK728_01367	COG5006	permease, DMT superfamily
FK728_01369	COG1560	Kdo2-lipid A biosynthetic process
FK728_01371	COG2814	Major facilitator Superfamily
FK728_01375	COG1250	3-hydroxyacyl-CoA dehydrogenase
FK728_01379	COG2801	Transposase and inactivated derivatives
FK728_01383	COG0753	catalase activity
FK728_01384	COG3038	cytochrome b561
FK728_01388	COG2267	carboxylic ester hydrolase activity
FK728_01389	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FK728_01390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FK728_01391	COG1012	belongs to the aldehyde dehydrogenase family
FK728_01392	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FK728_01394	COG1012	belongs to the aldehyde dehydrogenase family
FK728_01395	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FK728_01396	COG0583	DNA-binding transcription factor activity
FK728_01398	COG1414	Transcriptional regulator
FK728_01399	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FK728_01401	COG1840	ABC-type Fe3 transport system, periplasmic component
FK728_01402	COG3842	ATPase activity
FK728_01406	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FK728_01407	COG2814	Major facilitator Superfamily
FK728_01408	COG1960	acyl-CoA dehydrogenase activity
FK728_01411	COG1024	Enoyl-CoA hydratase
FK728_01413	COG2814	Major facilitator Superfamily
FK728_01415	COG0183	Belongs to the thiolase family
FK728_01416	COG1250	3-hydroxyacyl-CoA dehydrogenase
FK728_01417	COG1028	Short-chain dehydrogenase reductase Sdr
FK728_01418	COG1024	Enoyl-CoA hydratase
FK728_01419	COG1960	acyl-CoA dehydrogenase activity
FK728_01420	COG2814	Major facilitator Superfamily
FK728_01421	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FK728_01422	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FK728_01424	COG2814	Major facilitator Superfamily
FK728_01426	COG1960	acyl-CoA dehydrogenase activity
FK728_01429	COG0583	DNA-binding transcription factor activity
FK728_01432	COG1024	Enoyl-CoA hydratase
FK728_01433	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FK728_01434	COG1960	acyl-CoA dehydrogenase activity
FK728_01435	COG1309	transcriptional regulator
FK728_01436	COG0318	PFAM AMP-dependent synthetase and ligase
FK728_01441	COG0583	DNA-binding transcription factor activity
FK728_01452	COG1028	Short-chain dehydrogenase reductase Sdr
FK728_01456	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FK728_01460	COG0784	Response regulator, receiver
FK728_01460	COG2205	protein histidine kinase activity
FK728_01470	COG0765	amino acid transport
FK728_01471	COG0765	amino acid transport
FK728_01472	COG1126	abc transporter atp-binding protein
FK728_01473	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FK728_01474	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FK728_01476	COG1280	lysine exporter protein (LysE YggA)
FK728_01477	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FK728_01478	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FK728_01479	COG1045	serine acetyltransferase
FK728_01482	COG0583	DNA-binding transcription factor activity
FK728_01483	COG0625	glutathione transferase activity
FK728_01484	COG0625	glutathione transferase activity
FK728_01485	COG0583	DNA-binding transcription factor activity
FK728_01487	COG1346	cytolysis
FK728_01491	COG2814	Major facilitator Superfamily
FK728_01493	COG0583	DNA-binding transcription factor activity
FK728_01495	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FK728_01496	COG3052	prosthetic group binding
FK728_01500	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FK728_01504	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FK728_01506	COG1294	oxidase, subunit
FK728_01507	COG1271	oxidase subunit
FK728_01511	COG0477	Major facilitator Superfamily
FK728_01513	COG4521	taurine ABC transporter
FK728_01514	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FK728_01515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FK728_01516	COG2175	clavaminate synthase activity
FK728_01518	COG1953	Uracil, thiamine, allantoin
FK728_01520	COG0583	DNA-binding transcription factor activity
FK728_01522	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FK728_01525	COG0640	Transcriptional regulator
FK728_01526	COG0798	PFAM Bile acid sodium symporter
FK728_01527	COG0583	DNA-binding transcription factor activity
FK728_01530	COG3634	alkyl hydroperoxide reductase activity
FK728_01538	COG0436	Aminotransferase
FK728_01540	COG0386	Belongs to the glutathione peroxidase family
FK728_01543	COG0436	Aminotransferase
FK728_01548	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FK728_01553	COG0012	GTP binding
FK728_01554	COG2011	ABC-type metal ion transport system permease component
FK728_01555	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FK728_01557	COG1464	Belongs to the NlpA lipoprotein family
FK728_01563	COG0765	amino acid transport
FK728_01564	COG0765	amino acid transport
FK728_01565	COG1126	abc transporter atp-binding protein
FK728_01567	COG1522	sequence-specific DNA binding
FK728_01570	COG1309	transcriptional regulator
FK728_01575	COG0583	DNA-binding transcription factor activity
FK728_01577	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FK728_01579	COG0697	spore germination
FK728_01584	COG3121	Chaperone
FK728_01585	COG3539	Fimbrial protein
FK728_01590	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FK728_01590	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FK728_01599	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FK728_01601	COG2353	YceI-like domain
FK728_01603	COG3698	Phosphodiester glycosidase
FK728_01606	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FK728_01607	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FK728_01607	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FK728_01607	COG0506	proline dehydrogenase activity
FK728_01609	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FK728_01610	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FK728_01614	COG1132	(ABC) transporter
FK728_01615	COG3122	Protein conserved in bacteria
FK728_01616	COG3619	membrane
FK728_01618	COG0640	Transcriptional regulator
FK728_01620	COG2850	peptidyl-arginine hydroxylation
FK728_01621	COG0424	maF-like protein
FK728_01625	COG0191	fructose-bisphosphate aldolase activity
FK728_01626	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FK728_01629	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FK728_01631	COG1192	Involved in chromosome partitioning
FK728_01632	COG1475	DNA binding
FK728_01633	COG0811	peptide transport
FK728_01635	COG1132	(ABC) transporter
FK728_01636	COG1663	tetraacyldisaccharide 4'-kinase activity
FK728_01640	COG0084	hydrolase, TatD family'
FK728_01643	COG2165	general secretion pathway protein
FK728_01649	COG0590	tRNA wobble adenosine to inosine editing
FK728_01653	COG0776	regulation of translation
FK728_01659	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FK728_01660	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FK728_01668	COG4166	transmembrane transport
FK728_01670	COG0339	signal peptide processing
FK728_01672	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FK728_01679	COG0702	epimerase
FK728_01680	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FK728_01684	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FK728_01690	COG0316	Belongs to the HesB IscA family
FK728_01691	COG0822	iron-sulfur transferase activity
FK728_01696	COG0776	regulation of translation
FK728_01697	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FK728_01698	COG2207	Transcriptional regulator
FK728_01699	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FK728_01700	COG1960	acyl-CoA dehydrogenase activity
FK728_01701	COG1960	acyl-CoA dehydrogenase activity
FK728_01704	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FK728_01707	COG2814	Major facilitator Superfamily
FK728_01708	COG4264	IucA IucC family
FK728_01709	COG4264	IucA IucC family
FK728_01711	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FK728_01717	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FK728_01720	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FK728_01721	COG0406	alpha-ribazole phosphatase activity
FK728_01724	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FK728_01725	COG0730	response to heat
FK728_01729	COG4773	Receptor
FK728_01730	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FK728_01733	COG1131	(ABC) transporter
FK728_01734	COG0842	Transport permease protein
FK728_01735	COG0842	Transport permease protein
FK728_01746	COG2226	methyltransferase
FK728_01751	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FK728_01752	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FK728_01761	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FK728_01763	COG0133	tryptophan synthase activity
FK728_01766	COG3706	GGDEF domain
FK728_01769	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FK728_01771	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FK728_01772	COG0022	dehydrogenase e1 component
FK728_01773	COG0508	dehydrogenase complex catalyzes the overall conversion of
FK728_01774	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FK728_01776	COG1063	alcohol dehydrogenase
FK728_01777	COG3781	membrane
FK728_01779	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FK728_01779	COG3453	Protein conserved in bacteria
FK728_01781	COG0730	response to heat
FK728_01784	COG3708	Transcriptional regulator
FK728_01784	COG2207	Transcriptional regulator
FK728_01785	COG1733	regulation of RNA biosynthetic process
FK728_01786	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FK728_01791	COG4521	taurine ABC transporter
FK728_01796	COG0477	Major facilitator Superfamily
FK728_01798	COG1027	Aspartate ammonia-lyase
FK728_01801	COG0583	DNA-binding transcription factor activity
FK728_01802	COG0583	DNA-binding transcription factor activity
FK728_01803	COG0183	Belongs to the thiolase family
FK728_01804	COG2031	fatty acid transporter
FK728_01807	COG0583	DNA-binding transcription factor activity
FK728_01811	COG1309	transcriptional regulator
FK728_01813	COG2610	gluconate transmembrane transporter activity
FK728_01814	COG1028	Short-chain dehydrogenase reductase Sdr
FK728_01815	COG2207	Transcriptional regulator
FK728_01817	COG0412	Dienelactone hydrolase
FK728_01818	COG1028	Short-chain dehydrogenase reductase Sdr
FK728_01820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FK728_01823	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FK728_01823	COG0543	2 iron, 2 sulfur cluster binding
FK728_01824	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FK728_01825	COG4638	Rieske (2fe-2S)
FK728_01827	COG0725	ABC transporter, periplasmic molybdate-binding protein
FK728_01828	COG4149	molybdate abc transporter
FK728_01829	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FK728_01830	COG1028	Short-chain dehydrogenase reductase Sdr
FK728_01831	COG3433	isochorismatase activity
FK728_01831	COG1535	isochorismatase
FK728_01843	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FK728_01846	COG0753	catalase activity
FK728_01848	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FK728_01853	COG3539	Fimbrial protein
FK728_01857	COG2072	flavoprotein involved in K transport
FK728_01860	COG2205	protein histidine kinase activity
FK728_01861	COG0745	RESPONSE REGULATOR receiver
FK728_01862	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FK728_01863	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FK728_01864	COG1538	Outer membrane efflux protein
FK728_01869	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FK728_01871	COG1073	alpha beta
FK728_01883	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FK728_01901	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FK728_01905	COG1120	ATPase activity
FK728_01908	COG1064	alcohol dehydrogenase
FK728_01909	COG2207	Transcriptional regulator
FK728_01910	COG2084	Dehydrogenase
FK728_01912	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FK728_01913	COG0583	DNA-binding transcription factor activity
FK728_01915	COG0129	dihydroxy-acid dehydratase activity
FK728_01916	COG1012	belongs to the aldehyde dehydrogenase family
FK728_01919	COG1566	PFAM secretion protein HlyD family protein
FK728_01921	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FK728_01922	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FK728_01927	COG0583	DNA-binding transcription factor activity
FK728_01940	COG1309	transcriptional regulator
FK728_01942	COG1522	sequence-specific DNA binding
FK728_01943	COG0814	amino acid
FK728_01944	COG1473	amidohydrolase
FK728_01945	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FK728_01946	COG0251	oxidation-reduction process
FK728_01947	COG1309	transcriptional regulator
FK728_01952	COG0789	Transcriptional regulator
FK728_01954	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FK728_01959	COG1012	belongs to the aldehyde dehydrogenase family
FK728_01963	COG2186	Transcriptional regulator
FK728_01965	COG0583	DNA-binding transcription factor activity
FK728_01966	COG4948	Mandelate Racemase Muconate Lactonizing
FK728_01967	COG4829	muconolactone delta-isomerase
FK728_01969	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FK728_01970	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FK728_01971	COG0183	Belongs to the thiolase family
FK728_01972	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FK728_01974	COG1012	belongs to the aldehyde dehydrogenase family
FK728_01976	COG3733	amine oxidase
FK728_01978	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FK728_01980	COG1028	Short-chain dehydrogenase reductase Sdr
FK728_01982	COG4638	Rieske (2fe-2S)
FK728_01986	COG0154	amidase activity
FK728_01988	COG2814	Major facilitator Superfamily
FK728_01993	COG1960	acyl-CoA dehydrogenase activity
FK728_01994	COG0583	DNA-binding transcription factor activity
FK728_01995	COG1414	Transcriptional regulator
FK728_01998	COG2391	methyltransferase activity
FK728_02000	COG4993	Dehydrogenase
FK728_02003	COG4993	Dehydrogenase
FK728_02004	COG3659	wide pore channel activity
FK728_02005	COG3420	alginic acid biosynthetic process
FK728_02006	COG0710	3-dehydroquinate dehydratase activity
FK728_02007	COG3485	protocatechuate 3,4-dioxygenase
FK728_02008	COG3485	protocatechuate 3,4-dioxygenase
FK728_02009	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FK728_02010	COG2271	Major facilitator Superfamily
FK728_02011	COG0596	Alpha beta hydrolase
FK728_02012	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FK728_02013	COG0183	Belongs to the thiolase family
FK728_02014	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FK728_02015	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FK728_02017	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FK728_02020	COG2323	membrane
FK728_02029	COG1902	pentaerythritol trinitrate reductase activity
FK728_02029	COG0446	pyridine nucleotide-disulphide oxidoreductase
FK728_02032	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FK728_02034	COG0542	response to heat
FK728_02035	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FK728_02041	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FK728_02042	COG0569	domain protein
FK728_02043	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FK728_02046	COG4774	siderophore transport
FK728_02047	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FK728_02049	COG1585	Membrane protein implicated in regulation of membrane protease activity
FK728_02052	COG1294	oxidase, subunit
FK728_02053	COG4890	Cyd operon protein YbgT
FK728_02056	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FK728_02058	COG0552	protein localization to endoplasmic reticulum
FK728_02063	COG0517	IMP dehydrogenase activity
FK728_02063	COG0516	GMP reductase activity
FK728_02064	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FK728_02065	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FK728_02067	COG0583	DNA-binding transcription factor activity
FK728_02068	COG0024	Methionine aminopeptidase
FK728_02074	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FK728_02074	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FK728_02075	COG1105	Belongs to the carbohydrate kinase PfkB family
FK728_02076	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FK728_02076	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FK728_02076	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FK728_02079	COG3300	MHYT domain
FK728_02079	COG5001	Diguanylate cyclase
FK728_02082	COG2135	peptidase activity
FK728_02083	COG0659	secondary active sulfate transmembrane transporter activity
FK728_02086	COG1113	amino acid transport
FK728_02088	COG1522	sequence-specific DNA binding
FK728_02095	COG1011	Hydrolase
FK728_02096	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FK728_02098	COG2137	regulation of response to DNA damage stimulus
FK728_02100	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FK728_02104	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FK728_02107	COG0575	Belongs to the CDS family
FK728_02108	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FK728_02112	COG3852	Histidine kinase
FK728_02113	COG2204	response regulator
FK728_02114	COG1309	transcriptional regulator
FK728_02124	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FK728_02125	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FK728_02129	COG0697	spore germination
FK728_02130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FK728_02132	COG0303	'Molybdopterin
FK728_02133	COG0521	Mo-molybdopterin cofactor biosynthetic process
FK728_02133	COG0315	cyclic pyranopterin monophosphate synthase activity
FK728_02136	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FK728_02137	COG0243	molybdopterin cofactor binding
FK728_02139	COG0243	molybdopterin cofactor binding
FK728_02140	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FK728_02141	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FK728_02141	COG2146	nitrite reductase [NAD(P)H] activity
FK728_02143	COG0745	RESPONSE REGULATOR receiver
FK728_02144	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FK728_02144	COG1116	anion transmembrane transporter activity
FK728_02147	COG0511	ligase activity, forming carbon-carbon bonds
FK728_02150	COG2814	Major facilitator Superfamily
FK728_02154	COG0069	glutamate synthase activity
FK728_02158	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FK728_02160	COG1454	alcohol dehydrogenase
FK728_02161	COG0824	Thioesterase
FK728_02164	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FK728_02169	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FK728_02171	COG1028	Short-chain dehydrogenase reductase Sdr
FK728_02172	COG0183	Belongs to the thiolase family
FK728_02174	COG0583	DNA-binding transcription factor activity
FK728_02177	COG1522	sequence-specific DNA binding
FK728_02178	COG3135	benzoate transporter
FK728_02180	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FK728_02185	COG0589	response to stress
FK728_02186	COG0488	(ABC) transporter
FK728_02190	COG4773	Receptor
FK728_02196	COG0668	transmembrane transport
FK728_02198	COG1309	transcriptional regulator
FK728_02200	COG2801	Transposase and inactivated derivatives
FK728_02203	COG1605	Chorismate mutase
FK728_02211	COG0308	aminopeptidase N
FK728_02216	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FK728_02217	COG1454	alcohol dehydrogenase
FK728_02221	COG0531	amino acid
FK728_02222	COG4303	Ethanolamine ammonia lyase large subunit
FK728_02223	COG4302	ethanolamine ammonia-lyase activity
FK728_02224	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FK728_02224	COG0519	Catalyzes the synthesis of GMP from XMP
FK728_02230	COG0697	spore germination
FK728_02231	COG1923	regulation of RNA biosynthetic process
FK728_02233	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FK728_02234	COG0802	atpase or kinase
FK728_02238	COG1187	pseudouridine synthase activity
FK728_02241	COG0583	DNA-binding transcription factor activity
FK728_02244	COG2814	Major facilitator Superfamily
FK728_02245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FK728_02247	COG0471	metal ion transport
FK728_02254	COG0729	surface antigen
FK728_02258	COG0174	glutamine synthetase
FK728_02259	COG0745	RESPONSE REGULATOR receiver
FK728_02260	COG2205	protein histidine kinase activity
FK728_02262	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FK728_02263	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FK728_02269	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FK728_02270	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FK728_02271	COG1960	acyl-CoA dehydrogenase activity
FK728_02277	COG0583	DNA-binding transcription factor activity
FK728_02280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FK728_02282	COG3658	cytochrome
FK728_02283	COG1215	transferase activity, transferring glycosyl groups
FK728_02284	COG0726	polysaccharide deacetylase
FK728_02284	COG1649	PFAM Uncharacterised BCR, COG1649
FK728_02291	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FK728_02292	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FK728_02294	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FK728_02299	COG0305	Participates in initiation and elongation during chromosome replication
FK728_02300	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FK728_02302	COG1305	Transglutaminase-like
FK728_02304	COG2308	Evidence 4 Homologs of previously reported genes of
FK728_02310	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FK728_02311	COG0138	bifunctional purine biosynthesis protein purh
FK728_02312	COG0151	Belongs to the GarS family
FK728_02313	COG1464	Belongs to the NlpA lipoprotein family
FK728_02314	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FK728_02315	COG2011	ABC-type metal ion transport system permease component
FK728_02316	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FK728_02318	COG1301	dicarboxylic acid transport
FK728_02324	COG1794	racemase activity, acting on amino acids and derivatives
FK728_02328	COG0745	RESPONSE REGULATOR receiver
FK728_02329	COG0642	Histidine kinase
FK728_02330	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FK728_02332	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FK728_02340	COG2351	hydroxyisourate hydrolase activity
FK728_02342	COG3008	intermembrane lipid transfer
FK728_02342	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FK728_02343	COG2995	paraquat-inducible protein a
FK728_02345	COG2985	domain, Protein
FK728_02351	COG1051	belongs to the nudix hydrolase family
FK728_02352	COG0477	Major facilitator Superfamily
FK728_02362	COG2186	Transcriptional regulator
FK728_02364	COG0786	glutamate:sodium symporter activity
FK728_02365	COG3243	poly(R)-hydroxyalkanoic acid synthase
FK728_02370	COG3111	PFAM Bacterial OB fold (BOF) protein
FK728_02383	COG3210	domain, Protein
FK728_02386	COG3210	domain, Protein
FK728_02386	COG3210	domain, Protein
FK728_02386	COG3210	domain, Protein
FK728_02387	COG2831	hemolysin activation secretion protein
FK728_02392	COG2815	serine threonine protein kinase
FK728_02392	COG0515	serine threonine protein kinase
FK728_02397	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FK728_02398	COG1610	YqeY-like protein
FK728_02399	COG4783	chaperone-mediated protein folding
FK728_02404	COG1286	toxin biosynthetic process
FK728_02410	COG0778	Nitroreductase
FK728_02412	COG0513	Belongs to the DEAD box helicase family
FK728_02416	COG2363	Small membrane protein
FK728_02422	COG1234	tRNA 3'-trailer cleavage
FK728_02423	COG2195	Cleaves the N-terminal amino acid of tripeptides
FK728_02425	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FK728_02427	COG2819	hydrolase of the alpha beta superfamily
FK728_02428	COG1960	acyl-CoA dehydrogenase activity
FK728_02429	COG1301	dicarboxylic acid transport
FK728_02430	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FK728_02431	COG3139	Protein of unknown function (DUF1315)
FK728_02432	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FK728_02433	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FK728_02435	COG0494	nUDIX hydrolase
FK728_02437	COG0642	Histidine kinase
FK728_02438	COG0745	RESPONSE REGULATOR receiver
FK728_02442	COG1720	tRNA m6t6A37 methyltransferase activity
FK728_02445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FK728_02447	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FK728_02449	COG4598	ABC transporter
FK728_02450	COG4160	amino acid transport
FK728_02451	COG4215	(ABC) transporter
FK728_02454	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FK728_02456	COG1538	Outer membrane efflux protein
FK728_02462	COG1131	(ABC) transporter
FK728_02463	COG0842	Transport permease protein
FK728_02466	COG0772	Belongs to the SEDS family
FK728_02467	COG2951	lytic endotransglycosylase activity
FK728_02472	COG2207	Transcriptional regulator
FK728_02476	COG0052	Belongs to the universal ribosomal protein uS2 family
FK728_02477	COG0024	Methionine aminopeptidase
FK728_02479	COG2223	nitrite transmembrane transporter activity
FK728_02482	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FK728_02483	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FK728_02484	COG1960	acyl-CoA dehydrogenase activity
FK728_02487	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FK728_02488	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FK728_02489	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FK728_02493	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FK728_02494	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FK728_02495	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FK728_02502	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FK728_02505	COG3104	oligopeptide transport
FK728_02507	COG0512	Glutamine amidotransferase of anthranilate synthase
FK728_02508	COG0308	aminopeptidase N
FK728_02514	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FK728_02520	COG3739	integral membrane protein
FK728_02525	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FK728_02527	COG1132	(ABC) transporter
FK728_02530	COG1535	isochorismatase
FK728_02530	COG3433	isochorismatase activity
FK728_02531	COG1021	2,3-dihydroxybenzoate-AMP ligase
FK728_02532	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FK728_02534	COG4774	siderophore transport
FK728_02535	COG4607	ABC-type enterochelin transport system periplasmic component
FK728_02536	COG4604	ABC transporter, ATP-binding protein
FK728_02537	COG4605	iron ion homeostasis
FK728_02538	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FK728_02541	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FK728_02544	COG2964	Protein conserved in bacteria
FK728_02546	COG1741	Belongs to the pirin family
FK728_02551	COG2879	small protein
FK728_02552	COG1966	Carbon starvation protein
FK728_02556	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FK728_02560	COG2211	Major facilitator Superfamily
FK728_02561	COG1067	ATP-dependent peptidase activity
FK728_02562	COG0583	DNA-binding transcription factor activity
FK728_02567	COG1686	Belongs to the peptidase S11 family
FK728_02568	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FK728_02575	COG0616	signal peptide processing
FK728_02576	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FK728_02578	COG0573	inorganic phosphate transmembrane transporter activity
FK728_02579	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FK728_02580	COG1113	amino acid transport
FK728_02581	COG3961	Belongs to the TPP enzyme family
FK728_02582	COG1522	sequence-specific DNA binding
FK728_02584	COG0076	glutamate decarboxylase activity
FK728_02585	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FK728_02588	COG2249	NAD(P)H dehydrogenase (quinone) activity
FK728_02590	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FK728_02597	COG0352	thiamine-phosphate diphosphorylase activity
FK728_02602	COG0612	Peptidase, M16
FK728_02605	COG0583	DNA-binding transcription factor activity
FK728_02606	COG0477	Major facilitator Superfamily
FK728_02610	COG1187	pseudouridine synthase activity
FK728_02613	COG1686	Belongs to the peptidase S11 family
FK728_02614	COG1252	NADH dehydrogenase
FK728_02616	COG0415	Belongs to the DNA photolyase family
FK728_02619	COG1215	transferase activity, transferring glycosyl groups
FK728_02625	COG2070	2-Nitropropane dioxygenase
FK728_02636	COG0556	nucleotide-excision repair
FK728_02645	COG4221	oxidoreductase activity
FK728_02647	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FK728_02648	COG1381	Involved in DNA repair and RecF pathway recombination
FK728_02650	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FK728_02653	COG0681	Belongs to the peptidase S26 family
FK728_02656	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FK728_02661	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FK728_02662	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FK728_02663	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FK728_02665	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FK728_02666	COG4208	sulfate ABC transporter
FK728_02667	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FK728_02668	COG0583	DNA-binding transcription factor activity
FK728_02669	COG4625	pathogenesis
FK728_02672	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FK728_02675	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FK728_02677	COG1051	belongs to the nudix hydrolase family
FK728_02677	COG1056	cytidyltransferase-related domain
FK728_02678	COG1024	Enoyl-CoA hydratase
FK728_02679	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FK728_02680	COG2814	Major facilitator Superfamily
FK728_02681	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FK728_02681	COG0047	phosphoribosylformylglycinamidine synthase activity
FK728_02686	COG1473	amidohydrolase
FK728_02687	COG0824	Thioesterase
FK728_02691	COG0823	Involved in the tonB-independent uptake of proteins
FK728_02695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FK728_02702	COG0628	permease
FK728_02704	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FK728_02705	COG0596	Alpha beta hydrolase
FK728_02706	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FK728_02706	COG0616	signal peptide processing
FK728_02708	COG0658	competence protein
FK728_02708	COG2333	competence protein COMEC
FK728_02709	COG1136	(ABC) transporter
FK728_02710	COG4591	ABC-type transport system involved in lipoprotein release permease component
FK728_02717	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FK728_02721	COG0463	Glycosyl transferase, family 2
FK728_02727	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FK728_02728	COG1280	lysine exporter protein (LysE YggA)
FK728_02730	COG0019	diaminopimelate decarboxylase activity
FK728_02732	COG1113	amino acid transport
FK728_02735	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FK728_02737	COG3339	Conserved Protein
FK728_02738	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FK728_02739	COG0243	molybdopterin cofactor binding
FK728_02740	COG1929	Belongs to the glycerate kinase type-1 family
FK728_02743	COG0778	Nitroreductase
FK728_02748	COG2801	Transposase and inactivated derivatives
FK728_02752	COG3811	Belongs to the UPF0386 family
FK728_02759	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FK728_02762	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FK728_02766	COG0741	lytic transglycosylase activity
FK728_02770	COG0584	glycerophosphoryl diester phosphodiesterase
FK728_02771	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FK728_02775	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FK728_02779	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FK728_02780	COG0477	Major facilitator Superfamily
FK728_02790	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FK728_02791	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FK728_02796	COG0505	Belongs to the CarA family
FK728_02799	COG1309	transcriptional regulator
FK728_02800	COG0251	oxidation-reduction process
FK728_02802	COG0589	response to stress
FK728_02805	COG2843	Capsule synthesis protein
FK728_02811	COG2321	neutral zinc metallopeptidase
FK728_02812	COG2354	Protein conserved in bacteria
FK728_02816	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FK728_02819	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FK728_02820	COG1053	succinate dehydrogenase
FK728_02821	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FK728_02822	COG2009	succinate dehydrogenase
FK728_02829	COG2921	Belongs to the UPF0250 family
FK728_02830	COG0321	lipoyl(octanoyl) transferase activity
FK728_02833	COG0531	amino acid
FK728_02835	COG1733	regulation of RNA biosynthetic process
FK728_02836	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FK728_02837	COG1648	precorrin-2 dehydrogenase activity
FK728_02837	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FK728_02840	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FK728_02845	COG0671	phosphoesterase, PA-phosphatase related
FK728_02846	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FK728_02848	COG1538	Outer membrane efflux protein
FK728_02849	COG0393	Putative heavy-metal-binding
FK728_02850	COG0393	Putative heavy-metal-binding
FK728_02852	COG1028	Short-chain dehydrogenase reductase Sdr
FK728_02854	COG0525	valine-tRNA ligase activity
FK728_02859	COG0583	DNA-binding transcription factor activity
FK728_02860	COG0004	ammonium transporteR
FK728_02861	COG0004	ammonium transporteR
FK728_02863	COG0642	Histidine kinase
FK728_02864	COG0745	RESPONSE REGULATOR receiver
FK728_02865	COG2194	sulfuric ester hydrolase activity
FK728_02869	COG1752	Esterase of the alpha-beta hydrolase superfamily
FK728_02872	COG2315	Protein conserved in bacteria
FK728_02873	COG0142	geranyltranstransferase activity
FK728_02874	COG2828	Protein conserved in bacteria
FK728_02875	COG1113	amino acid transport
FK728_02877	COG0582	viral genome integration into host DNA
FK728_02885	COG0305	Participates in initiation and elongation during chromosome replication
FK728_02895	COG0464	growth
FK728_02899	COG2207	Transcriptional regulator
FK728_02904	COG2249	NAD(P)H dehydrogenase (quinone) activity
FK728_02908	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FK728_02910	COG1530	ribonuclease E activity
FK728_02911	COG0424	maF-like protein
FK728_02912	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FK728_02913	COG1792	Involved in formation and maintenance of cell shape
FK728_02914	COG1077	Cell shape determining protein MreB Mrl
FK728_02915	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FK728_02917	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FK728_02923	COG3590	peptidase
FK728_02924	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FK728_02925	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FK728_02926	COG1752	Esterase of the alpha-beta hydrolase superfamily
FK728_02927	COG1115	amino acid carrier protein
FK728_02930	COG2814	Major facilitator Superfamily
FK728_02931	COG1289	transmembrane transporter activity
FK728_02941	COG1376	ErfK ybiS ycfS ynhG family protein
FK728_02942	COG2832	Protein of unknown function (DUF454)
FK728_02944	COG5510	response to toxic substance
FK728_02948	COG0840	transmembrane signaling receptor activity
FK728_02956	COG3422	double-strand break repair
FK728_02957	COG2824	Alkylphosphonate utilization operon protein PhnA
FK728_02958	COG3189	MarR family transcriptional regulator
FK728_02960	COG0354	folic acid binding
FK728_02961	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FK728_02963	COG0679	Auxin Efflux Carrier
FK728_02964	COG1902	pentaerythritol trinitrate reductase activity
FK728_02965	COG4772	TonB-dependent receptor
FK728_02966	COG2094	Belongs to the DNA glycosylase MPG family
FK728_02972	COG2233	PERMEase
FK728_02974	COG0833	amino acid
FK728_02975	COG1690	Belongs to the RtcB family
FK728_02977	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FK728_02977	COG2885	chlorophyll binding
FK728_02979	COG0183	Belongs to the thiolase family
FK728_02983	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FK728_02987	COG2207	Transcriptional regulator
FK728_02988	COG0183	Belongs to the thiolase family
FK728_02994	COG1272	protein, Hemolysin III
FK728_02995	COG0477	Major facilitator Superfamily
FK728_02998	COG0450	alkyl hydroperoxide reductase
FK728_03002	COG0285	dihydrofolate synthase activity
FK728_03009	COG0133	tryptophan synthase activity
FK728_03011	COG4206	TonB-dependent receptor
FK728_03012	COG2096	Adenosyltransferase
FK728_03016	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FK728_03017	COG0745	RESPONSE REGULATOR receiver
FK728_03018	COG2205	protein histidine kinase activity
FK728_03020	COG1960	acyl-CoA dehydrogenase activity
FK728_03021	COG1960	acyl-CoA dehydrogenase activity
FK728_03037	COG0438	transferase activity, transferring glycosyl groups
FK728_03038	COG0726	polysaccharide deacetylase
FK728_03041	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FK728_03042	COG2205	protein histidine kinase activity
FK728_03049	COG1862	Preprotein translocase
FK728_03051	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FK728_03052	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FK728_03054	COG3781	membrane
FK728_03055	COG0613	PHP domain protein
FK728_03057	COG2350	Protein conserved in bacteria
FK728_03063	COG1607	acyl-coa hydrolase
FK728_03066	COG3453	Protein conserved in bacteria
FK728_03066	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FK728_03075	COG2199	diguanylate cyclase activity
FK728_03077	COG1408	metallophosphoesterase
FK728_03078	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FK728_03080	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FK728_03084	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FK728_03085	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FK728_03086	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FK728_03088	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FK728_03090	COG2969	positive regulation of protein catabolic process
FK728_03094	COG1960	acyl-CoA dehydrogenase activity
FK728_03095	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FK728_03098	COG1309	transcriptional regulator
FK728_03099	COG1960	acyl-CoA dehydrogenase activity
FK728_03108	COG1183	phosphatidylcholine synthase activity
FK728_03109	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FK728_03115	COG0739	heme binding
FK728_03115	COG1196	nuclear chromosome segregation
FK728_03115	COG0741	lytic transglycosylase activity
FK728_03117	COG1702	phosphate starvation-inducible protein PhoH
FK728_03124	COG1295	ribonuclease BN
FK728_03125	COG0697	spore germination
FK728_03126	COG2169	Transcriptional regulator
FK728_03127	COG0179	Fumarylacetoacetate (FAA) hydrolase
FK728_03136	COG0557	exoribonuclease II activity
FK728_03137	COG0339	signal peptide processing
FK728_03138	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FK728_03145	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FK728_03146	COG1960	acyl-CoA dehydrogenase activity
FK728_03151	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FK728_03153	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FK728_03177	COG0626	cystathionine gamma-synthase activity
FK728_03178	COG0433	COG0433 Predicted ATPase
FK728_03179	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FK728_03179	COG1017	nitric oxide dioxygenase activity
FK728_03180	COG1959	2 iron, 2 sulfur cluster binding
FK728_03183	COG1301	dicarboxylic acid transport
FK728_03184	COG1946	Acyl-CoA thioesterase
FK728_03188	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FK728_03189	COG1040	competence protein
FK728_03190	COG0494	nUDIX hydrolase
FK728_03192	COG0598	Magnesium transport protein CorA
FK728_03194	COG2854	intermembrane phospholipid transfer
FK728_03196	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FK728_03197	COG1127	ABC transporter
FK728_03199	COG0513	Belongs to the DEAD box helicase family
FK728_03203	COG0408	coproporphyrinogen oxidase activity
FK728_03206	COG1960	acyl-CoA dehydrogenase activity
FK728_03208	COG1983	PspC domain protein
FK728_03209	COG0517	IMP dehydrogenase activity
FK728_03220	COG0583	DNA-binding transcription factor activity
FK728_03228	COG1012	belongs to the aldehyde dehydrogenase family
FK728_03230	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FK728_03231	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FK728_03232	COG0833	amino acid
FK728_03239	COG0628	permease
FK728_03241	COG1289	transmembrane transporter activity
FK728_03244	COG2249	NAD(P)H dehydrogenase (quinone) activity
FK728_03245	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FK728_03247	COG0277	FAD linked oxidase domain protein
FK728_03248	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FK728_03253	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FK728_03254	COG5380	lipid catabolic process
FK728_03258	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FK728_03268	COG0194	GDP metabolic process
FK728_03270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FK728_03274	COG3307	-O-antigen
FK728_03278	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FK728_03279	COG1704	LemA family
FK728_03281	COG0493	'glutamate synthase
FK728_03282	COG0070	glutamate synthase
FK728_03282	COG0069	glutamate synthase activity
FK728_03282	COG0067	glutamate synthase
FK728_03292	COG2226	methyltransferase
FK728_03295	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FK728_03296	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FK728_03305	COG0833	amino acid
FK728_03321	COG0488	(ABC) transporter
FK728_03323	COG4221	oxidoreductase activity
FK728_03324	COG0659	secondary active sulfate transmembrane transporter activity
FK728_03327	COG0745	RESPONSE REGULATOR receiver
FK728_03329	COG0427	acetyl-CoA hydrolase
FK728_03335	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FK728_03339	COG1132	(ABC) transporter
FK728_03342	COG2329	Antibiotic biosynthesis monooxygenase
FK728_03345	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FK728_03359	COG2249	NAD(P)H dehydrogenase (quinone) activity
FK728_03360	COG1733	regulation of RNA biosynthetic process
FK728_03366	COG1733	regulation of RNA biosynthetic process
FK728_03370	COG2801	Transposase and inactivated derivatives
FK728_03372	COG0667	Aldo Keto reductase
FK728_03376	COG0583	DNA-binding transcription factor activity
FK728_03377	COG2814	Major facilitator Superfamily
FK728_03385	COG1335	isochorismatase
FK728_03387	COG1012	belongs to the aldehyde dehydrogenase family
FK728_03388	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FK728_03390	COG1113	amino acid transport
FK728_03392	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FK728_03395	COG2814	Major facilitator Superfamily
FK728_03397	COG0351	phosphomethylpyrimidine kinase
FK728_03397	COG0352	thiamine-phosphate diphosphorylase activity
FK728_03397	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FK728_03401	COG1309	transcriptional regulator
FK728_03402	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FK728_03403	COG3706	GGDEF domain
FK728_03405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FK728_03407	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FK728_03408	COG3162	membrane
FK728_03409	COG2205	protein histidine kinase activity
FK728_03409	COG2198	Histidine kinase
FK728_03409	COG0784	Response regulator, receiver
FK728_03414	COG1522	sequence-specific DNA binding
FK728_03415	COG1335	isochorismatase
FK728_03416	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FK728_03420	COG0668	transmembrane transport
FK728_03421	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FK728_03422	COG1519	Transferase
FK728_03423	COG1902	pentaerythritol trinitrate reductase activity
FK728_03428	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FK728_03433	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FK728_03433	COG0426	domain, Protein
FK728_03434	COG4774	siderophore transport
FK728_03435	COG2119	membrane
FK728_03437	COG0508	dehydrogenase complex catalyzes the overall conversion of
FK728_03439	COG4942	peptidase
FK728_03442	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FK728_03444	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FK728_03448	COG0189	ligase activity
FK728_03452	COG0708	Exodeoxyribonuclease III
FK728_03453	COG1393	Belongs to the ArsC family
FK728_03456	COG3706	GGDEF domain
FK728_03463	COG2351	hydroxyisourate hydrolase activity
FK728_03464	COG2233	PERMEase
FK728_03466	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FK728_03468	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FK728_03470	COG3150	esterase
FK728_03477	COG1705	Flagellar rod assembly protein muramidase FlgJ
FK728_03477	COG1388	LysM domain
FK728_03478	COG3501	Rhs element vgr protein
FK728_03480	COG2918	glutathione biosynthetic process
FK728_03483	COG2733	membrane
FK728_03484	COG0436	Aminotransferase
FK728_03485	COG0534	Mate efflux family protein
FK728_03502	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FK728_03503	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FK728_03505	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FK728_03506	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FK728_03509	COG0010	Belongs to the arginase family
FK728_03515	COG2188	Transcriptional regulator
FK728_03517	COG0523	cobalamin synthesis protein
FK728_03519	COG1113	amino acid transport
FK728_03521	COG0625	glutathione transferase activity
FK728_03525	COG1683	Conserved Protein
FK728_03526	COG0534	Mate efflux family protein
FK728_03527	COG0385	Bile acid
FK728_03528	COG1335	isochorismatase
FK728_03529	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FK728_03533	COG2116	formate transmembrane transporter activity
FK728_03534	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FK728_03535	COG2133	pyrroloquinoline quinone binding
FK728_03536	COG2983	Belongs to the UPF0260 family
FK728_03538	COG0400	carboxylic ester hydrolase activity
FK728_03540	COG1194	a g-specific adenine glycosylase
FK728_03543	COG2818	Glycosylase
FK728_03544	COG1064	alcohol dehydrogenase
FK728_03545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FK728_03547	COG0583	DNA-binding transcription factor activity
FK728_03548	COG0656	L-ascorbic acid biosynthetic process
FK728_03549	COG2814	Major facilitator Superfamily
FK728_03556	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FK728_03559	COG2233	PERMEase
FK728_03560	COG0583	DNA-binding transcription factor activity
FK728_03565	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FK728_03567	COG0733	neurotransmitter:sodium symporter activity
FK728_03569	COG0625	glutathione transferase activity
FK728_p200009	COG2826	transposase and inactivated derivatives, IS30 family
FK728_p300005	COG0358	DNA primase activity
FK728_p300012	COG0194	GDP metabolic process
FK728_p300017	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FK728_p300025	COG0587	DNA-directed DNA polymerase activity
FK728_p300029	COG0587	DNA-directed DNA polymerase activity
FK728_p300032	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FK728_p300032	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FK728_p300042	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FK728_p300042	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FK728_p300043	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FK728_p300049	COG3316	Transposase and inactivated derivatives
FK728_p300051	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FK728_p300056	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FK728_p300069	COG3586	endonuclease activity
FK728_p300083	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FK728_p300092	COG3316	Transposase and inactivated derivatives
FK728_p300099	COG3173	Aminoglycoside phosphotransferase
FK728_p300107	COG2963	transposase activity
FK728_p300109	COG4372	Transposase
FK728_p300117	COG1388	LysM domain
FK728_p300120	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FK728_p300124	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system