locus-tag class description KAB07_00001 ENOG4105C5H ABC transporter KAB07_00002 ENOG4105DQR SNARE associated Golgi KAB07_00004 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) KAB07_00006 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) KAB07_00008 ENOG4105VG0 50S ribosomal protein l34 KAB07_00011 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins KAB07_00014 ENOG4105PGM cation diffusion facilitator family transporter KAB07_00015 ENOG4105T95 Thiol disulfide interChange protein KAB07_00017 ENOG4108UGV hypoxanthine phosphoribosyltransferase KAB07_00019 ENOG4107QUY Guanine deaminase KAB07_00021 ENOG4106032 Glutathionylspermidine synthase KAB07_00023 ENOG4105DU1 integral membrane protein, terc KAB07_00024 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase KAB07_00026 ENOG4105DFU Cell wall formation (By similarity) KAB07_00028 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) KAB07_00029 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit KAB07_00030 ENOG4105CVE Lytic murein transglycosylase KAB07_00041 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) KAB07_00048 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase KAB07_00050 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) KAB07_00051 ENOG4105DTN riboflavin biosynthesis protein ribF KAB07_00053 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) KAB07_00054 ENOG4108R86 Transcriptional regulator KAB07_00055 ENOG4108VM9 ABC, transporter KAB07_00056 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component KAB07_00057 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) KAB07_00058 ENOG4105GVF (ABC) transporter KAB07_00059 ENOG4105GVF (ABC) transporter KAB07_00060 ENOG4107QZM n-acetylglutamate synthase KAB07_00063 ENOG4105UBK short-chain dehydrogenase reductase KAB07_00064 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) KAB07_00067 ENOG41062JF Transcriptional regulator KAB07_00072 ENOG4105HSS phospholipase C KAB07_00073 ENOG4105HSS phospholipase C KAB07_00075 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase KAB07_00076 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase KAB07_00077 ENOG4105CJR Integral membrane protein (MviN KAB07_00078 ENOG4108V1T peptidylprolyl cis-trans isomerase KAB07_00079 ENOG4108V1T peptidylprolyl cis-trans isomerase KAB07_00080 ENOG4105D75 Capsular exopolysaccharide family KAB07_00082 ENOG4105DAY polysaccharide export protein KAB07_00083 ENOG4107QQG Dehydrogenase KAB07_00092 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase KAB07_00095 ENOG4107UKG Glycosyl transferase, family 4 KAB07_00096 ENOG4105D3Q Sugar transferase KAB07_00097 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase KAB07_00098 ENOG4105C6Y Udp-glucose 6-dehydrogenase KAB07_00100 ENOG4105CMR udp-glucose 4-epimerase KAB07_00101 ENOG4107QKV phosphomannomutase KAB07_00102 ENOG4105DAA L-lactate KAB07_00103 ENOG41073TP transcriptional regulator KAB07_00105 ENOG4105CXG d-lactate dehydrogenase KAB07_00106 ENOG4105CGF Aromatic amino acid aminotransferase KAB07_00107 ENOG4105DRR Transcriptional regulator, GntR family KAB07_00108 ENOG4105CR4 methylisocitrate lyase KAB07_00109 ENOG4105BZN citrate synthase KAB07_00110 ENOG4108I0Z Aconitate hydratase KAB07_00123 ENOG4105D3G Pseudouridine synthase KAB07_00128 ENOG4105EW9 transcriptional regulator AsnC family KAB07_00131 ENOG4105M4H endoribonuclease L-psp KAB07_00132 ENOG4105C85 amino acid KAB07_00133 ENOG4105C85 amino acid KAB07_00135 ENOG4105C26 Dehydrogenase KAB07_00136 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase KAB07_00138 ENOG4105C1G acyl-Coa dehydrogenase KAB07_00139 ENOG4105E39 Enoyl-CoA hydratase KAB07_00140 ENOG4105E39 Enoyl-CoA hydratase KAB07_00141 ENOG4105CSH Transporter KAB07_00147 ENOG4105C1G acyl-Coa dehydrogenase KAB07_00156 ENOG4107PSF BolA-like protein KAB07_00158 ENOG4107QJE Chromosome Partitioning Protein KAB07_00161 ENOG4105DQR SNARE associated Golgi KAB07_00162 ENOG4108VBZ doxx family KAB07_00163 ENOG4106MP8 UPF0754 membrane protein KAB07_00164 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) KAB07_00168 ENOG4105EUB pirin domain protein KAB07_00173 ENOG4107R1I NAD-dependent malic enzyme KAB07_00174 ENOG4105EZR dyp-type peroxidase family protein KAB07_00176 ENOG4105FAV ABC, transporter KAB07_00177 ENOG4105FDK ABC transporter KAB07_00182 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) KAB07_00190 ENOG4108V06 Glutathione peroxidase KAB07_00192 ENOG4107RTG Major Facilitator superfamily KAB07_00193 ENOG4108IND Tetr family transcriptional regulator KAB07_00196 ENOG4105C79 DNA protecting protein DprA KAB07_00203 ENOG4105Y7M Transcriptional regulator, TetR family KAB07_00210 ENOG4105C6T cysteine synthase KAB07_00212 ENOG4105CS1 NAD(P)H quinone oxidoreductase KAB07_00216 ENOG4105CCT upf0313 protein KAB07_00219 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) KAB07_00222 ENOG4108URH decarboxylase KAB07_00223 ENOG4105EE5 Membrane protein terC KAB07_00225 ENOG4105EN6 Membrane KAB07_00226 ENOG41079KZ Major Facilitator Superfamily KAB07_00227 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) KAB07_00228 ENOG4105CEY Amp-dependent synthetase and ligase KAB07_00231 ENOG4105F0N pyrophosphate phospho-hydrolase KAB07_00232 ENOG4105EPF Outer membrane porin KAB07_00235 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) KAB07_00237 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family KAB07_00238 ENOG4105C0P Mg chelatase subunit ChlI KAB07_00245 ENOG4105CHH sulfate transporter KAB07_00247 ENOG4105C0P Mg chelatase subunit ChlI KAB07_00250 ENOG4105BZU Histidine kinase KAB07_00252 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) KAB07_00260 ENOG4108K5H permease YjgP YjgQ family protein KAB07_00261 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) KAB07_00262 ENOG4105CN1 protease KAB07_00263 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family KAB07_00264 ENOG4107TUY Histidine kinase KAB07_00266 ENOG41061WM D-Alanyl-D-Alanine KAB07_00268 ENOG4105D6E homoserine dehydrogenase KAB07_00269 ENOG4105T95 Thiol disulfide interChange protein KAB07_00270 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) KAB07_00272 ENOG4105CE1 Ferrous iron transport protein b KAB07_00275 ENOG4105CNI cell division protein FtsW KAB07_00276 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) KAB07_00277 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters KAB07_00278 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) KAB07_00283 ENOG4108RNG Permease of the drug metabolite transporter KAB07_00284 ENOG4105DFG type I secretion outer membrane protein KAB07_00285 ENOG4108UTW Plays a role in the regulation of phosphate uptake KAB07_00288 ENOG4108HRK Histidine kinase KAB07_00289 ENOG4108NEV two component transcriptional regulator, LytTR family KAB07_00290 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) KAB07_00295 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS KAB07_00298 ENOG4105GVR general secretion pathway protein D KAB07_00299 ENOG4105TV9 FHA Domain-Containing protein KAB07_00300 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) KAB07_00308 ENOG4105PM1 preprotein translocase subunit SecE KAB07_00309 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) KAB07_00319 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) KAB07_00320 ENOG4105D3Y Na H antiporter KAB07_00323 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) KAB07_00326 ENOG4107ZXU DSBA oxidoreductase KAB07_00340 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase KAB07_00341 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) KAB07_00347 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) KAB07_00349 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) KAB07_00352 ENOG4105C2N RNA methyltransferase TrmH family group 3 KAB07_00354 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) KAB07_00357 ENOG4107QHF type ii secretion system protein e KAB07_00359 ENOG4107EJC Preprotein translocase subunit SecG KAB07_00364 ENOG4105CHV Transcription elongation factor NusA KAB07_00367 ENOG4105KJM monovalent cation h antiporter subunit g KAB07_00368 ENOG4105W4C monovalent cation H antiporter subunit F KAB07_00369 ENOG4105SC1 monovalent cation H antiporter subunit E KAB07_00370 ENOG4107R4Z monovalent cation h antiporter subunit d KAB07_00371 ENOG4108ZE9 Monovalent cation H antiporter subunit C KAB07_00372 ENOG4105D65 subunit l KAB07_00375 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase KAB07_00376 ENOG41061H0 Monooxygenase KAB07_00379 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) KAB07_00381 ENOG4105CSR polyphosphate kinase 2 KAB07_00383 ENOG4105DSY exodeoxyribonuclease V, gamma KAB07_00384 ENOG4107QKA exodeoxyribonuclease V beta KAB07_00385 ENOG4107QYX exodeoxyribonuclease v alpha KAB07_00389 ENOG4107QUT magnesium and cobalt transport protein CorA KAB07_00390 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) KAB07_00391 ENOG4105DVC DnaJ domain protein KAB07_00393 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) KAB07_00394 ENOG4105CKD glutathione-regulated potassium-efflux system protein KAB07_00395 ENOG4105C25 Primosomal protein n' KAB07_00396 ENOG4105D7Q type ii secretion system KAB07_00397 ENOG4108VAU general secretion pathway protein G KAB07_00399 ENOG4108Z7R Chaperone CsaA KAB07_00400 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) KAB07_00401 ENOG4108JU5 Magnesium and cobalt efflux protein KAB07_00402 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) KAB07_00403 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase KAB07_00405 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) KAB07_00408 ENOG4105C5X domain protein KAB07_00409 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) KAB07_00417 ENOG4107T8P acyl-Coa dehydrogenase KAB07_00419 ENOG4107QI1 Mate efflux family protein KAB07_00421 ENOG4105CSA Coproporphyrinogen iii oxidase KAB07_00422 ENOG4105EMU Dehydrogenase KAB07_00423 ENOG4105CBN LysR family transcriptional regulator KAB07_00427 ENOG4105C03 ribonuclease KAB07_00428 ENOG4105EI2 Pseudouridine synthase KAB07_00429 ENOG4107XGZ Hydrolase KAB07_00430 ENOG4105D29 Helix-turn-helix type 11 domain protein KAB07_00433 ENOG4108W5M transcriptional regulator KAB07_00436 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase KAB07_00441 ENOG4105DUM transcriptional regulator, lysR family KAB07_00446 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) KAB07_00457 ENOG4105CK2 sodium dicarboxylate symporter KAB07_00459 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase KAB07_00460 ENOG4105N14 lysine exporter protein LysE YggA KAB07_00461 ENOG4105C5H ABC transporter KAB07_00462 ENOG41069P5 Protein slyX homolog KAB07_00464 ENOG4105KVH Transcriptional regulator KAB07_00466 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) KAB07_00469 ENOG4105C4R Atp-dependent dna helicase KAB07_00470 ENOG4105VFU Rna-binding protein KAB07_00474 ENOG4105CKD glutathione-regulated potassium-efflux system protein KAB07_00475 ENOG4105W0E 50S ribosomal protein L33 KAB07_00476 ENOG4105KDC 50s ribosomal protein l28 KAB07_00477 ENOG4107RGH Aldehyde dehydrogenase KAB07_00479 ENOG4105CIY formyltetrahydrofolate deformylase KAB07_00499 ENOG4105DWV Homoserine O-trans-acetylase KAB07_00501 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) KAB07_00503 ENOG4108ESX Receptor KAB07_00505 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) KAB07_00509 ENOG4107GFK fumarate KAB07_00510 ENOG4108DNC Involved in acetate metabolism (By similarity) KAB07_00511 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) KAB07_00512 ENOG4105C01 Dihydroxy-acid dehydratase KAB07_00513 ENOG4108UHU Aldolase KAB07_00514 ENOG4105C6Z Gluconate KAB07_00515 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family KAB07_00516 ENOG4105C26 Dehydrogenase KAB07_00518 ENOG4106HB6 Alpha beta hydrolase KAB07_00521 ENOG4105CN1 protease KAB07_00524 ENOG4105WVQ Fe-S assembly protein IscX KAB07_00528 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) KAB07_00532 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) KAB07_00536 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) KAB07_00539 ENOG4105CEY Amp-dependent synthetase and ligase KAB07_00542 ENOG4105C84 Histidine ammonia-lyase KAB07_00548 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) KAB07_00550 ENOG4105C2D reductase KAB07_00551 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) KAB07_00555 ENOG4105VW4 glutaredoxin 3 KAB07_00557 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) KAB07_00558 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) KAB07_00560 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH KAB07_00561 ENOG4105ENJ RND efflux system, outer membrane lipoprotein KAB07_00562 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) KAB07_00563 ENOG4105DJY efflux transporter, rnd family, mfp subunit KAB07_00568 ENOG4105C7K acetolactate synthase KAB07_00569 ENOG4108ZP8 Acetolactate synthase small subunit KAB07_00571 ENOG4105BZU Histidine kinase KAB07_00575 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) KAB07_00578 ENOG4105F8V Hydrolase, tatD family KAB07_00579 ENOG4107QM5 aconitate hydratase KAB07_00581 ENOG4105CUZ uba thif-type nad fad binding protein KAB07_00582 ENOG4107RSM transcriptional regulator KAB07_00584 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) KAB07_00587 ENOG4106UX7 integral membrane protein KAB07_00588 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) KAB07_00589 ENOG4105W8H transhydrogenase (subunit alpha KAB07_00590 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) KAB07_00593 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) KAB07_00594 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase KAB07_00595 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase KAB07_00596 ENOG4105BZU Histidine kinase KAB07_00597 ENOG4105C6T cysteine synthase KAB07_00600 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) KAB07_00602 ENOG4105DXN mazG family KAB07_00603 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein KAB07_00604 ENOG4105DJ0 Poly(A) Polymerase KAB07_00605 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase KAB07_00609 ENOG41080Z8 PHOSPHOCARRIER protein KAB07_00610 ENOG4105N42 UPF0307 protein KAB07_00611 ENOG4105CEY Amp-dependent synthetase and ligase KAB07_00614 ENOG4105CYM Glutathione S-transferase KAB07_00615 ENOG4105W39 Membrane KAB07_00618 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) KAB07_00623 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) KAB07_00626 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) KAB07_00628 ENOG4105C9X ppx gppa phosphatase KAB07_00630 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) KAB07_00631 ENOG4105II7 pyrroline-5-carboxylate reductase KAB07_00632 ENOG4108VIA integral membrane protein KAB07_00633 ENOG4105C2M dna polymerase I KAB07_00637 ENOG4107QHF type ii secretion system protein e KAB07_00638 ENOG4108ZHJ Organic hydroperoxide resistance protein KAB07_00639 ENOG4105K56 Transcriptional regulator KAB07_00653 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) KAB07_00654 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) KAB07_00655 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) KAB07_00657 ENOG4105CRQ synthase (Component I) KAB07_00666 ENOG4108Z0R Transferase KAB07_00667 ENOG41072GX Peptidase M22 Glycoprotease KAB07_00672 ENOG4105DJV ribulose-phosphate 3-epimerase KAB07_00673 ENOG4108HCJ Hydrolase KAB07_00675 ENOG4105E3B Multicopper oxidase KAB07_00676 ENOG4105VR0 copper resistance KAB07_00679 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) KAB07_00680 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) KAB07_00681 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) KAB07_00688 ENOG4105ETT transcriptional Regulator, LysR family KAB07_00689 ENOG4105C1G acyl-Coa dehydrogenase KAB07_00690 ENOG4107RGD Major Facilitator superfamily KAB07_00691 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F KAB07_00693 ENOG4107EFR Flavocytochrome c KAB07_00694 ENOG4106P55 Transcriptional regulator KAB07_00698 ENOG4106P55 Transcriptional regulator KAB07_00700 ENOG4105CH2 amidohydrolase KAB07_00704 ENOG4105ETT transcriptional Regulator, LysR family KAB07_00706 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) KAB07_00707 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) KAB07_00710 ENOG4108HWY Beta-lactamase KAB07_00713 ENOG4107QJE Chromosome Partitioning Protein KAB07_00714 ENOG4105ECI YeeC-like protein KAB07_00716 ENOG4105F6A helicase KAB07_00723 ENOG4105JAB phenazine biosynthesis protein, phzf family KAB07_00727 ENOG4105DZG Dehydrogenase KAB07_00741 ENOG4105EB3 Histidine kinase KAB07_00742 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) KAB07_00744 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) KAB07_00745 ENOG4107EXC regulatoR KAB07_00746 ENOG4105E0F Histidine kinase KAB07_00748 ENOG4105BZU Histidine kinase KAB07_00752 ENOG4105GKE subunit e KAB07_00753 ENOG4107QIZ NADH dehydrogenase KAB07_00754 ENOG4108IEH NADH dehydrogenase subunit g KAB07_00757 ENOG4107UFS subunit j KAB07_00759 ENOG4105D65 subunit l KAB07_00760 ENOG4105C8S subunit m KAB07_00764 ENOG4105DUM transcriptional regulator, lysR family KAB07_00765 ENOG4105DP0 ferredoxin-NADP reductase KAB07_00770 ENOG4105CBX hi0933 family KAB07_00771 ENOG4105K6H D-cysteine desulfhydrase KAB07_00777 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) KAB07_00779 ENOG4105D1F ATP-binding protein KAB07_00790 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) KAB07_00792 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY KAB07_00795 ENOG4105HF0 Membrane KAB07_00797 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) KAB07_00801 ENOG4106UW1 Major Facilitator superfamily KAB07_00802 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase KAB07_00803 ENOG4108K4C ec 3.1.3.12 KAB07_00804 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) KAB07_00806 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) KAB07_00807 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) KAB07_00809 ENOG4105FE9 pseudouridine synthase KAB07_00810 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) KAB07_00811 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) KAB07_00812 ENOG4107RTD sua5 ycio yrdc ywlc family protein KAB07_00813 ENOG4108BPE -transporting atpase KAB07_00814 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein KAB07_00816 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase KAB07_00817 ENOG4105CHR reductase KAB07_00819 ENOG4109066 lysm domain bon superfamily protein KAB07_00820 ENOG4105DWF phosphomethylpyrimidine kinase KAB07_00822 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) KAB07_00828 ENOG4105C5T Phosphoribosyl pyrophosphate synthase KAB07_00833 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) KAB07_00836 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) KAB07_00837 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane KAB07_00838 ENOG4105C34 Pseudouridine synthase KAB07_00839 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase KAB07_00843 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding KAB07_00846 ENOG4105EJC lysr family transcriptional regulator KAB07_00847 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) KAB07_00848 ENOG4105C94 Transporter KAB07_00850 ENOG4105DVW rieske (2Fe-2S) KAB07_00851 ENOG4105C26 Dehydrogenase KAB07_00852 ENOG4105E3J oxidoreductase KAB07_00853 ENOG4105E3J oxidoreductase KAB07_00856 ENOG4105C4K Nad synthetase KAB07_00858 ENOG4105EUB pirin domain protein KAB07_00859 ENOG4108YXA Membrane KAB07_00868 ENOG4105KEG ribosomal-protein-alanine acetyltransferase KAB07_00870 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) KAB07_00871 ENOG4105C3M thioredoxin reductase KAB07_00872 ENOG4105CNU cell division protein FtsK KAB07_00877 ENOG4107QMS site-determining protein KAB07_00880 ENOG4106HNH Acyl-transferase KAB07_00881 ENOG4108ZG0 Ompa motb domain protein KAB07_00883 ENOG4105C4R Atp-dependent dna helicase KAB07_00885 ENOG4107QKV phosphomannomutase KAB07_00888 ENOG4105E7A Glutamine amidotransferase KAB07_00893 ENOG41090R7 Ferric uptake KAB07_00894 ENOG4105CZX twitching motility protein KAB07_00895 ENOG4105CZX twitching motility protein KAB07_00896 ENOG4105DFA alanine racemase domain protein KAB07_00897 ENOG4105EYH Exonuclease KAB07_00898 ENOG4107RH8 nuclease SbcCD subunit D KAB07_00902 ENOG4105ECP epimerase KAB07_00903 ENOG4105MWK D-amino acid dehydrogenase, small subunit KAB07_00904 ENOG4105D52 delta-aminolevulinic acid dehydratase KAB07_00905 ENOG4108VUY thioesterase Superfamily protein KAB07_00906 ENOG4105CW7 secretion protein, HlyD family KAB07_00907 ENOG4105C0R drug resistance transporter emrb qaca subfamily KAB07_00910 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) KAB07_00918 ENOG41083X2 DNA polymerase III, epsilon subunit KAB07_00980 ENOG4105K4U addiction module toxin, RelE StbE family KAB07_00988 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) KAB07_01015 ENOG4105C54 Major Facilitator superfamily KAB07_01016 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) KAB07_01018 ENOG4108SF5 RNA Polymerase KAB07_01024 ENOG4108YNN Heme oxygenase KAB07_01029 ENOG4105D5Q Arginine ornithine antiporter KAB07_01030 ENOG4107QK5 Homocysteine s-methyltransferase KAB07_01035 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) KAB07_01036 ENOG4105C94 Transporter KAB07_01037 ENOG4105C94 Transporter KAB07_01041 ENOG4105CKI cobalamin synthesis protein KAB07_01043 ENOG4108VWS Yaeq family KAB07_01045 ENOG4107BJW polysaccharide deacetylase KAB07_01046 ENOG4105CND Glycosyl transferase, family 2 KAB07_01048 ENOG4106YT9 Enoyl-CoA hydratase KAB07_01051 ENOG41069M3 Transcriptional regulator KAB07_01055 ENOG4105CHR reductase KAB07_01057 ENOG4108DNI pyridine nucleotide-disulfide oxidoreductase KAB07_01058 ENOG4105DJB Major Facilitator Superfamily KAB07_01060 ENOG4108MXF Alpha Beta Hydrolase KAB07_01061 ENOG4105CHR reductase KAB07_01064 ENOG4105C7K acetolactate synthase KAB07_01066 ENOG4105CSH Transporter KAB07_01068 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) KAB07_01069 ENOG4105CSV Glutaminase KAB07_01070 ENOG4108R6W Transcriptional regulator, ARAC family KAB07_01071 ENOG4105EU0 Major facilitator Superfamily KAB07_01072 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) KAB07_01074 ENOG4108PZW LysR family Transcriptional regulator KAB07_01076 ENOG4105CSP Major Facilitator Superfamily KAB07_01079 ENOG4105C3R Methionine synthase KAB07_01080 ENOG4105CJ3 phosphate transporter KAB07_01084 ENOG4105E6M Sulphatase-modifying factor protein KAB07_01085 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) KAB07_01088 ENOG4107RNH Outer membrane receptor FepA KAB07_01092 ENOG4108UJV acyl-CoA thioesterase i KAB07_01093 ENOG4108I0Y (ABC) transporter KAB07_01094 ENOG4105CV6 ABC transporter, permease KAB07_01095 ENOG4107U91 Rhomboid family KAB07_01099 ENOG4105C5Q Transcriptional regulator KAB07_01101 ENOG4107QZF nitrite reductase NADPH large subunit KAB07_01102 ENOG4105VCQ rubredoxin KAB07_01106 ENOG4108MRJ KAB07_01109 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) KAB07_01112 ENOG4105D4T Citrate transporter KAB07_01113 ENOG4105C37 (CBS) domain KAB07_01115 ENOG4107RET Isocitrate lyase KAB07_01121 ENOG4105CQM Urea amidohydrolase subunit alpha KAB07_01123 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) KAB07_01126 ENOG4106H78 methyltransferase KAB07_01127 ENOG4105CJN penicillin-binding protein KAB07_01131 ENOG4105CSM endonuclease III KAB07_01132 ENOG4108R3D Electron transport complex KAB07_01133 ENOG4105D82 Glutamate dehydrogenase KAB07_01135 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b KAB07_01140 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase KAB07_01205 ENOG4105DR5 peptidase KAB07_01214 ENOG4105DIJ Phosphoethanolamine transferase KAB07_01221 ENOG4107RAQ aminopeptidase KAB07_01222 ENOG4105D0A hydroxylase KAB07_01223 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family KAB07_01227 ENOG4108ZUB Lysine exporter protein (Lyse ygga) KAB07_01228 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) KAB07_01230 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) KAB07_01232 ENOG4105W4M Transport-associated protein KAB07_01234 ENOG4105E09 nadh pyrophosphatase KAB07_01236 ENOG4107RZZ dna polymerase iii epsilon subunit KAB07_01237 ENOG4105E9H Lytic Murein transglycosylase KAB07_01237 ENOG4105E9H Lytic Murein transglycosylase KAB07_01239 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component KAB07_01240 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component KAB07_01241 ENOG4108JQ5 ABC transporter KAB07_01245 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) KAB07_01249 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase KAB07_01252 ENOG4108M3P Membrane KAB07_01253 ENOG4105D01 (LipO)protein KAB07_01257 ENOG4105CNA YD repeat protein KAB07_01259 ENOG4105F95 Monooxygenase KAB07_01266 ENOG4105F95 Monooxygenase KAB07_01268 ENOG4105C7N Xanthine uracil vitamin C permease KAB07_01269 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) KAB07_01270 ENOG4105CPW cytochrome b561 KAB07_01272 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) KAB07_01274 ENOG4105CFH Aspartokinase KAB07_01276 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase KAB07_01278 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis KAB07_01281 ENOG4105CPC Aldo Keto reductase KAB07_01284 ENOG4107RYR Transcriptional regulator, Crp Fnr family KAB07_01285 ENOG4108UKZ OsmC family KAB07_01288 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit KAB07_01294 ENOG4105CD3 dihydroorotase KAB07_01295 ENOG4108ZG0 Ompa motb domain protein KAB07_01297 ENOG4108TGY Glutathione S-transferase KAB07_01298 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) KAB07_01300 ENOG4108K3A Glutathione S-transferase KAB07_01302 ENOG4108JU3 Alkyl hydroperoxide reductase KAB07_01304 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) KAB07_01306 ENOG4105D3R alkyl hydroperoxide reductase KAB07_01307 ENOG4105CQ7 ATP-dependent helicase KAB07_01310 ENOG4105D2S major facilitator superfamily KAB07_01311 ENOG4105DKK Benzoate KAB07_01312 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase KAB07_01313 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein KAB07_01314 ENOG4108UKV benzoate 1,2-dioxygenase KAB07_01315 ENOG4105FUY alpha subunit KAB07_01316 ENOG4108KB2 LysR family Transcriptional regulator KAB07_01326 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) KAB07_01333 ENOG410829K Lysine exporter protein (Lyse ygga) KAB07_01334 ENOG4105VEQ Cold shock protein KAB07_01336 ENOG4105II7 pyrroline-5-carboxylate reductase KAB07_01342 ENOG4107YPT transcriptional regulator KAB07_01349 ENOG4105C2X Arabinose 5-phosphate isomerase KAB07_01350 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase KAB07_01352 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA KAB07_01353 ENOG4108IUZ ABC transporter KAB07_01354 ENOG4105DFG type I secretion outer membrane protein KAB07_01362 ENOG4108Z4U Ferredoxin KAB07_01366 ENOG4107AQZ Membrane KAB07_01367 ENOG4105BZU Histidine kinase KAB07_01368 ENOG4105D1S lipid A biosynthesis KAB07_01370 ENOG4105D2S major facilitator superfamily KAB07_01374 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) KAB07_01380 ENOG4105CNA YD repeat protein KAB07_01383 ENOG4108WAV Transcriptional regulator KAB07_01384 ENOG4105C5A transporter KAB07_01388 ENOG4108JIK carboxylase KAB07_01389 ENOG4107R4J Chloride channel KAB07_01394 ENOG4105R8C Transcriptional regulator KAB07_01396 ENOG4105E2A Dehydrogenase KAB07_01399 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase KAB07_01400 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF KAB07_01401 ENOG4105KVH Transcriptional regulator KAB07_01404 ENOG4105MRR Transcriptional regulator (By similarity) KAB07_01406 ENOG4108HW3 (ABC) transporter KAB07_01412 ENOG4108Z4X TRANSCRIPTIONal KAB07_01415 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) KAB07_01419 ENOG4105MWK D-amino acid dehydrogenase, small subunit KAB07_01424 ENOG4105CZJ Aldehyde dehydrogenase KAB07_01425 ENOG4107QTZ amino acid KAB07_01426 ENOG4105EJQ L-serine dehydratase KAB07_01427 ENOG4105DXM phenylacetic acid degradation protein KAB07_01428 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit KAB07_01429 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit KAB07_01430 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit KAB07_01431 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit KAB07_01432 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) KAB07_01433 ENOG4105E39 Enoyl-CoA hydratase KAB07_01434 ENOG4108UKI Enoyl-CoA hydratase KAB07_01435 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase KAB07_01436 ENOG4105CHU acetyl-coa acetyltransferase KAB07_01437 ENOG4105DZS Phenylacetate-CoA ligase KAB07_01438 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein KAB07_01440 ENOG4107YAU phenylacetic acid degradation protein KAB07_01447 ENOG4107VGR Catalase KAB07_01448 ENOG4105CPW cytochrome b561 KAB07_01452 ENOG4108MXF Alpha Beta Hydrolase KAB07_01453 ENOG4105MXW flavin reductase domain protein, FMN-binding KAB07_01454 ENOG4108M8W Monooxygenase KAB07_01455 ENOG4105C26 Dehydrogenase KAB07_01456 ENOG4105ETS cytosine purines uracil thiamine allantoin KAB07_01458 ENOG4105C26 Dehydrogenase KAB07_01459 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase KAB07_01460 ENOG4105HEI LysR family (Transcriptional regulator KAB07_01462 ENOG4107HP6 Transcriptional regulator KAB07_01463 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase KAB07_01465 ENOG4105C4Y ABC transporter KAB07_01466 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) KAB07_01467 ENOG4107RCV ABC transporter, permease KAB07_01469 ENOG4107STF Involved in phosphonate degradation (By similarity) KAB07_01470 ENOG4108KAZ Involved in phosphonate degradation (By similarity) KAB07_01471 ENOG4107RGD Major Facilitator superfamily KAB07_01472 ENOG4105C1G acyl-Coa dehydrogenase KAB07_01475 ENOG4108UKI Enoyl-CoA hydratase KAB07_01476 ENOG4105EA8 2-Nitropropane dioxygenase KAB07_01477 ENOG4105EQ0 Major Facilitator superfamily KAB07_01479 ENOG4105CHU acetyl-coa acetyltransferase KAB07_01480 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase KAB07_01481 ENOG4105CHR reductase KAB07_01482 ENOG4105E39 Enoyl-CoA hydratase KAB07_01483 ENOG4105C1G acyl-Coa dehydrogenase KAB07_01484 ENOG4107RGD Major Facilitator superfamily KAB07_01485 ENOG4107QP7 CoA-transferase subunit A KAB07_01486 ENOG4107QNJ CoA-transferase subunit B KAB07_01488 ENOG4105EQ0 Major Facilitator superfamily KAB07_01490 ENOG4105CSU acyl-Coa dehydrogenase KAB07_01493 ENOG4105CC0 LysR family Transcriptional regulator KAB07_01496 ENOG4105E39 Enoyl-CoA hydratase KAB07_01497 ENOG4107QX3 carboxylase KAB07_01498 ENOG4105C1G acyl-Coa dehydrogenase KAB07_01499 ENOG4105R8C Transcriptional regulator KAB07_01500 ENOG4105CEY Amp-dependent synthetase and ligase KAB07_01501 ENOG4105CEY Amp-dependent synthetase and ligase KAB07_01505 ENOG4105HEI LysR family (Transcriptional regulator KAB07_01516 ENOG4105CYX Short-chain dehydrogenase reductase Sdr KAB07_01520 ENOG4105KT5 UmuD protein KAB07_01522 ENOG4105EW9 transcriptional regulator AsnC family KAB07_01524 ENOG4105BZU Histidine kinase KAB07_01525 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase KAB07_01527 ENOG4105EAD ABC transporter KAB07_01528 ENOG4108HW4 amino acid AbC transporter KAB07_01529 ENOG4105CDA abc transporter atp-binding protein KAB07_01530 ENOG4107RP9 extracellular solute-binding protein, family 3 KAB07_01531 ENOG4105CT1 (ABC) transporter KAB07_01532 ENOG4105EXG Transcriptional regulator KAB07_01534 ENOG4105C9B Cysteine desulfurase KAB07_01535 ENOG4105ESN nucleotide-binding protein KAB07_01536 ENOG4105D7W serine acetyltransferase KAB07_01538 ENOG4105CHR reductase KAB07_01539 ENOG4105CBN LysR family transcriptional regulator KAB07_01540 ENOG4105CYM Glutathione S-transferase KAB07_01541 ENOG4108SHQ Glutathione S-transferase KAB07_01542 ENOG4105CMU LysR family (Transcriptional regulator KAB07_01543 ENOG4105VAW lrga family KAB07_01544 ENOG41067MG lrgb family KAB07_01548 ENOG4105DXI Major Facilitator superfamily KAB07_01550 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase KAB07_01551 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) KAB07_01554 ENOG4105PSI phosphoribosyl-dephospho-CoA transferase KAB07_01555 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase KAB07_01558 ENOG4108K70 Transcriptional regulator KAB07_01559 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family KAB07_01561 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii KAB07_01562 ENOG4105C4M (Ubiquinol oxidase) subunit I KAB07_01566 ENOG4105C54 Major Facilitator superfamily KAB07_01569 ENOG4106FTQ Taurine ABC transporter, periplasmic KAB07_01570 ENOG4108IY8 ABC, transporter KAB07_01571 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component KAB07_01572 ENOG4105E2B Taurine dioxygenase KAB07_01574 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease KAB07_01576 ENOG4105CBN LysR family transcriptional regulator KAB07_01578 ENOG4105CPN adenine deaminase KAB07_01581 ENOG41082YX Transcriptional regulator, arsr family KAB07_01582 ENOG4105D6J arsenicaL-resistance protein KAB07_01583 ENOG4108KB2 LysR family Transcriptional regulator KAB07_01586 ENOG4108JU3 Alkyl hydroperoxide reductase KAB07_01591 ENOG4105C0B DNA polymerase III (alpha subunit) KAB07_01594 ENOG4105CHM Aminotransferase KAB07_01596 ENOG4108V06 Glutathione peroxidase KAB07_01597 ENOG4105E7U AraC family transcriptional regulator KAB07_01603 ENOG4105ZED uncharacterized protein ygaH KAB07_01604 ENOG4108UMN azlc family KAB07_01609 ENOG4105C3G gtp-binding protein KAB07_01610 ENOG4108UMI ABC transporter, permease KAB07_01611 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) KAB07_01612 ENOG4105D01 (LipO)protein KAB07_01613 ENOG4105D01 (LipO)protein KAB07_01616 ENOG4107T8P acyl-Coa dehydrogenase KAB07_01619 ENOG4105EAD ABC transporter KAB07_01620 ENOG4105DRP amino acid AbC transporter KAB07_01621 ENOG4105CDA abc transporter atp-binding protein KAB07_01623 ENOG4105EW9 transcriptional regulator AsnC family KAB07_01628 ENOG41067SE Tetr family transcriptional regulator KAB07_01633 ENOG4105CC0 LysR family Transcriptional regulator KAB07_01635 ENOG4105ETS cytosine purines uracil thiamine allantoin KAB07_01637 ENOG4108IPJ Membrane KAB07_01642 ENOG4105GQR Chaperone KAB07_01643 ENOG4105X0I Fimbrial KAB07_01647 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) KAB07_01648 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) KAB07_01652 ENOG4108HWY Beta-lactamase KAB07_01657 ENOG4105CV1 Transketolase (EC 2.2.1.1) KAB07_01659 ENOG4108YYC ycei family KAB07_01661 ENOG4108T58 Mg2 transport protein CorA KAB07_01664 ENOG4105YGK Pfam:UPF0157 KAB07_01665 ENOG4105C26 Dehydrogenase KAB07_01666 ENOG4105EW9 transcriptional regulator AsnC family KAB07_01667 ENOG4105CK7 Sodium proline symporter KAB07_01668 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) KAB07_01670 ENOG4108ZX5 transcriptional regulator KAB07_01672 ENOG4105BZ1 (ABC) transporter KAB07_01673 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme KAB07_01674 ENOG4105XPP Protein of unknown function (DUF1275) KAB07_01676 ENOG41080HT Transcriptional regulator, arsr family KAB07_01678 ENOG4105EZE Cupin 4 family protein KAB07_01679 ENOG4108UHJ MAF-like protein KAB07_01683 ENOG4105D2N Aldolase KAB07_01684 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) KAB07_01685 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) KAB07_01686 ENOG4105EHM Aminoglycoside phosphotransferase KAB07_01687 ENOG4108S0S Nucleotidyl transferase KAB07_01689 ENOG4107QJE Chromosome Partitioning Protein KAB07_01690 ENOG4105FA0 parb-like partition protein KAB07_01693 ENOG4105BZ1 (ABC) transporter KAB07_01694 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) KAB07_01696 ENOG4107QRG dna polymerase iii KAB07_01698 ENOG4105F8V Hydrolase, tatD family KAB07_01703 ENOG4108RTD type II secretion system protein K KAB07_01707 ENOG4108Z6B deaminase KAB07_01710 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) KAB07_01711 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) KAB07_01715 ENOG4107RN6 Monooxygenase KAB07_01717 ENOG4105D6Z AFG1 family ATPase KAB07_01718 ENOG4107QP3 malate synthase g KAB07_01720 ENOG4105SG9 biopolymer transport protein, ExbD KAB07_01729 ENOG4105DGW oligopeptidase A KAB07_01731 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component KAB07_01735 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase KAB07_01738 ENOG4105K4T epimerase KAB07_01739 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) KAB07_01743 ENOG4108JA2 transcriptioN-repair coupling factor KAB07_01745 ENOG4105F8J Adenylate Guanylate cyclase KAB07_01746 ENOG4108ZIT Ferredoxin, 2FE-2S KAB07_01749 ENOG4108Z4V iron-sulfur cluster assembly KAB07_01750 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins KAB07_01752 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family KAB07_01755 ENOG4105K70 DNA-binding protein KAB07_01756 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) KAB07_01757 ENOG4105E7U AraC family transcriptional regulator KAB07_01758 ENOG4105EEF Alkane 1-monooxygenase KAB07_01759 ENOG4105C1G acyl-Coa dehydrogenase KAB07_01760 ENOG4105C1G acyl-Coa dehydrogenase KAB07_01763 ENOG4108Z66 YbaK ebsC protein KAB07_01767 ENOG4105DUU IucA IucC family protein KAB07_01768 ENOG4105DJU Siderophore biosynthesis protein KAB07_01776 ENOG4107VXZ Hydrolase KAB07_01778 ENOG4108YZT Adenosylcobinamide kinase KAB07_01779 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) KAB07_01783 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) KAB07_01784 ENOG4107TSN permease KAB07_01788 ENOG4105CNM Receptor KAB07_01789 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) KAB07_01792 ENOG4105CJ1 ABC, transporter KAB07_01793 ENOG4107QWP ABC-2 type transporter KAB07_01794 ENOG4107QWP ABC-2 type transporter KAB07_01799 ENOG4105K59 histidine triad (HIT) protein KAB07_01805 ENOG4105F2W methyltransferase KAB07_01807 ENOG4105C28 cystathionine KAB07_01810 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) KAB07_01819 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) KAB07_01820 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) KAB07_01822 ENOG4105BZU Histidine kinase KAB07_01825 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) KAB07_01826 ENOG4107R0V Pyruvate dehydrogenase KAB07_01827 ENOG4105CPP Dehydrogenase, E1 component KAB07_01830 ENOG4105CHR reductase KAB07_01832 ENOG4105FFC UPF0187 protein KAB07_01834 ENOG4107QPB Beta-lactamase domain protein KAB07_01836 ENOG4108VCT Sulfite exporter TauE/SafE KAB07_01839 ENOG4105UEI Transcriptional Regulator AraC Family KAB07_01840 ENOG4105KVH Transcriptional regulator KAB07_01841 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) KAB07_01843 ENOG4105FDP GntR family transcriptional regulator KAB07_01846 ENOG4106FTQ Taurine ABC transporter, periplasmic KAB07_01847 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component KAB07_01851 ENOG4105CSH Transporter KAB07_01853 ENOG4108IJ0 Aspartate ammonia-lyase KAB07_01856 ENOG4107YNJ LysR family Transcriptional regulator KAB07_01858 ENOG4105CHU acetyl-coa acetyltransferase KAB07_01859 ENOG4105CRW Short chain fatty acid transporter KAB07_01860 ENOG4107QNJ CoA-transferase subunit B KAB07_01862 ENOG4108M0I Transcriptional regulator KAB07_01864 ENOG4105CY2 Citrate transporter KAB07_01865 ENOG4105DTD Dehydrogenase KAB07_01869 ENOG4105CF7 AraC family transcriptional regulator KAB07_01870 ENOG4105D2S major facilitator superfamily KAB07_01872 ENOG4105CHR reductase KAB07_01877 ENOG4105F57 Anthranilate dioxygenase reductase KAB07_01878 ENOG4108YS2 small subunit KAB07_01879 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit KAB07_01880 ENOG4105F4R Transcriptional regulator mode KAB07_01881 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein KAB07_01882 ENOG4105E0C molybdate abc transporter KAB07_01883 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) KAB07_01884 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase KAB07_01885 ENOG4105WQI isochorismatase KAB07_01887 ENOG4107T31 5'-nucleotidase KAB07_01893 ENOG4108IGT Dipeptidase KAB07_01897 ENOG4107RZC phospholipase d KAB07_01909 ENOG4105X0I Fimbrial KAB07_01913 ENOG4105CJP fad dependent oxidoreductase KAB07_01917 ENOG4105CT3 Monooxygenase KAB07_01919 ENOG4105ENJ RND efflux system, outer membrane lipoprotein KAB07_01920 ENOG4105BZS acriflavin resistance protein KAB07_01921 ENOG4105C1P efflux transporter, rnd family, mfp subunit KAB07_01922 ENOG4105CK6 Two component transcriptional regulator (Winged helix family KAB07_01923 ENOG4105E0F Histidine kinase KAB07_01924 ENOG4108821 RND type efflux pump KAB07_01925 ENOG4108R6W Transcriptional regulator, ARAC family KAB07_01928 ENOG4108BAS reductase KAB07_01939 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) KAB07_01947 ENOG4108UAJ Transcriptional regulator KAB07_01963 ENOG4105C5T Phosphoribosyl pyrophosphate synthase KAB07_01967 ENOG4105E0A ABC, transporter KAB07_01968 ENOG4105EHG Permease protein KAB07_01970 ENOG4105DQ4 alcohol dehydrogenase KAB07_01973 ENOG4105CF7 AraC family transcriptional regulator KAB07_01974 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase KAB07_01976 ENOG4105EXW epimerase dehydratase KAB07_01977 ENOG4105DDW LysR family Transcriptional regulator KAB07_01979 ENOG4105C01 Dihydroxy-acid dehydratase KAB07_01980 ENOG4105CZJ Aldehyde dehydrogenase KAB07_01983 ENOG4105CW7 secretion protein, HlyD family KAB07_01987 ENOG4105JSC dimethylmenaquinone methyltransferase KAB07_01988 ENOG4108JQ1 Dehydrogenase KAB07_01993 ENOG4106KR7 LysR family Transcriptional regulator KAB07_01996 ENOG4105FDP GntR family transcriptional regulator KAB07_02002 ENOG4105CKT filamentous hemagglutinin KAB07_02003 ENOG4105D5K Hemolysin activator protein KAB07_02008 ENOG4105CH2 amidohydrolase KAB07_02010 ENOG4105CKD glutathione-regulated potassium-efflux system protein KAB07_02011 ENOG4105D8V Glucose sorbosone dehydrogenase KAB07_02012 ENOG4105EJC lysr family transcriptional regulator KAB07_02013 ENOG4105CHJ isochorismatase hydrolase KAB07_02015 ENOG4107Z3H Transcriptional regulator, TetR family KAB07_02021 ENOG4105NAE bifunctional deaminase-reductase domain protein KAB07_02023 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase KAB07_02024 ENOG4105K56 Transcriptional regulator KAB07_02028 ENOG4105CH6 catalase KAB07_02031 ENOG4107RGH Aldehyde dehydrogenase KAB07_02034 ENOG41062QD Membrane KAB07_02036 ENOG4108JU7 Transcriptional regulator KAB07_02037 ENOG4105CHR reductase KAB07_02038 ENOG4105C1G acyl-Coa dehydrogenase KAB07_02042 ENOG4105CZJ Aldehyde dehydrogenase KAB07_02046 ENOG4107EJG GntR family transcriptional regulator KAB07_02048 ENOG4108KB2 LysR family Transcriptional regulator KAB07_02049 ENOG4105DTQ mandelate racemase muconate lactonizing KAB07_02050 ENOG4105NN7 muconolactone delta-isomerase KAB07_02052 ENOG4107QP7 CoA-transferase subunit A KAB07_02053 ENOG4107QNJ CoA-transferase subunit B KAB07_02054 ENOG4105CHU acetyl-coa acetyltransferase KAB07_02055 ENOG4105F2Z 3-oxoadipate enol-lactonase KAB07_02057 ENOG4105C26 Dehydrogenase KAB07_02059 ENOG4105F11 amine oxidase KAB07_02063 ENOG4105CHR reductase KAB07_02065 ENOG4105FUY alpha subunit KAB07_02069 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) KAB07_02071 ENOG4105DNH Major Facilitator KAB07_02076 ENOG4105C1G acyl-Coa dehydrogenase KAB07_02077 ENOG4108PTX LysR family Transcriptional regulator KAB07_02078 ENOG4107HP6 Transcriptional regulator KAB07_02081 ENOG4105MD1 YeeE YedE family protein KAB07_02083 ENOG4105DZG Dehydrogenase KAB07_02084 ENOG4105TW1 Carbohydrate-selective porin OprB KAB07_02085 ENOG4106JPM 3-dehydroshikimate dehydratase KAB07_02086 ENOG4105FF2 Type I DHQase KAB07_02087 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha KAB07_02088 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta KAB07_02089 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase KAB07_02090 ENOG4105D2S major facilitator superfamily KAB07_02091 ENOG4105F2Z 3-oxoadipate enol-lactonase KAB07_02092 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase KAB07_02093 ENOG4105CHU acetyl-coa acetyltransferase KAB07_02094 ENOG4107QNJ CoA-transferase subunit B KAB07_02095 ENOG4107QP7 CoA-transferase subunit A KAB07_02097 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) KAB07_02098 ENOG4107VMU Membrane KAB07_02107 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase KAB07_02110 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) KAB07_02112 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit KAB07_02113 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) KAB07_02119 ENOG4105C7B Threonine dehydratase KAB07_02121 ENOG4105CZN Potassium uptake protein KAB07_02122 ENOG4105HDD phospholipase KAB07_02124 ENOG4105E0K tonB-dependent siderophore receptor KAB07_02127 ENOG4105PV3 Inner membrane protein yqiJ KAB07_02130 ENOG4105C4M (Ubiquinol oxidase) subunit I KAB07_02131 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii KAB07_02135 ENOG41068P6 UPF0319 protein KAB07_02137 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) KAB07_02142 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) KAB07_02143 ENOG4105C8Y Acetylornithine aminotransferase KAB07_02144 ENOG4105M2J Glutaredoxin KAB07_02146 ENOG4105CC0 LysR family Transcriptional regulator KAB07_02147 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) KAB07_02148 ENOG4105CWM branched-chain amino acid transport system II carrier protein KAB07_02153 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) KAB07_02154 ENOG4105DE4 1-phosphofructokinase KAB07_02155 ENOG4105DM4 PTS System KAB07_02160 ENOG4105BZU Histidine kinase KAB07_02162 ENOG4105D8V Glucose sorbosone dehydrogenase KAB07_02163 ENOG4108RAV Conserved protein KAB07_02164 ENOG4105CHH sulfate transporter KAB07_02168 ENOG4105C85 amino acid KAB07_02170 ENOG4105F7P transcriptional regulator AsnC family KAB07_02175 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 KAB07_02176 ENOG4105VEJ Heat shock protein KAB07_02178 ENOG4105Y3E Modulates RecA activity (By similarity) KAB07_02180 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) KAB07_02185 ENOG4105DZP Membrane-associated zinc metalloprotease KAB07_02187 ENOG4105KNE Phosphatidate cytidylyltransferase KAB07_02188 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) KAB07_02192 ENOG4105CUX Signal transduction histidine kinase KAB07_02193 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family KAB07_02204 ENOG4105CMR udp-glucose 4-epimerase KAB07_02205 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) KAB07_02209 ENOG4105T38 integral membrane protein KAB07_02210 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family KAB07_02212 ENOG4105CVM Molybdenum cofactor synthesis domain protein KAB07_02213 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) KAB07_02216 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) KAB07_02223 ENOG4108IFG nitrite reductase, (NAD(P)H) KAB07_02224 ENOG4107QZF nitrite reductase NADPH large subunit KAB07_02226 ENOG4105CK6 Two component transcriptional regulator (Winged helix family KAB07_02230 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein KAB07_02231 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase KAB07_02233 ENOG4105D8G Major Facilitator superfamily KAB07_02237 ENOG4105CBC glutamate synthase KAB07_02243 ENOG4105C0A alcohol dehydrogenase KAB07_02245 ENOG4105HSS phospholipase C KAB07_02247 ENOG4107QMP dna polymerase iii subunits gamma and tau KAB07_02252 ENOG4105CHR reductase KAB07_02253 ENOG4105CHU acetyl-coa acetyltransferase KAB07_02255 ENOG4105C5Q Transcriptional regulator KAB07_02256 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) KAB07_02257 ENOG4108NIW Leucine export protein LeuE KAB07_02258 ENOG4105EW9 transcriptional regulator AsnC family KAB07_02259 ENOG4105DKK Benzoate KAB07_02261 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic KAB07_02266 ENOG41081QV Universal stress protein KAB07_02267 ENOG4105C5H ABC transporter KAB07_02271 ENOG4105CNM Receptor KAB07_02279 ENOG4105CUY Mechanosensitive ion channel KAB07_02281 ENOG4105R8C Transcriptional regulator KAB07_02283 ENOG4105EW9 transcriptional regulator AsnC family KAB07_02284 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) KAB07_02286 ENOG4105EMU Dehydrogenase KAB07_02288 ENOG4105CD8 aminopeptidase N KAB07_02292 ENOG4105F4I Transcriptional regulator KAB07_02294 ENOG4107QUV Domain protein KAB07_02295 ENOG4105C0A alcohol dehydrogenase KAB07_02297 ENOG4107RR1 TRANSCRIPTIONal KAB07_02299 ENOG4107R55 ethanolamine transporter KAB07_02300 ENOG4105CPD ethanolamine ammonia-lyase KAB07_02301 ENOG4107FQ9 ethanolamine ammonia-lyase KAB07_02302 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) KAB07_02305 ENOG4105F10 Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity) KAB07_02307 ENOG4108RCM Nitroreductase KAB07_02308 ENOG4108TZV Membrane KAB07_02309 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) KAB07_02311 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) KAB07_02312 ENOG4105K8N protein family UPF0079, ATPase KAB07_02319 ENOG4105DZ2 Transcriptional regulator KAB07_02322 ENOG4105F27 Major Facilitator KAB07_02323 ENOG4105EYW Ion transport protein KAB07_02325 ENOG4107QIJ Aconitate hydratase 2 KAB07_02328 ENOG4105CFU surface antigen KAB07_02329 ENOG4107S74 Lysophospholipid transporter LplT KAB07_02332 ENOG4105CFQ glutamine synthetase KAB07_02333 ENOG4105EEX Two component transcriptional regulator (Winged helix family KAB07_02334 ENOG4105C08 Histidine kinase KAB07_02336 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) KAB07_02337 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) KAB07_02341 ENOG4105D06 uba thif-type nad fad binding protein KAB07_02342 ENOG4108MEJ flavin reductase domain protein KAB07_02344 ENOG4105C1G acyl-Coa dehydrogenase KAB07_02347 ENOG4105GVF (ABC) transporter KAB07_02348 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component KAB07_02349 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) KAB07_02352 ENOG4105CC0 LysR family Transcriptional regulator KAB07_02355 ENOG4105DEN Luciferase family KAB07_02358 ENOG4105CND Glycosyl transferase, family 2 KAB07_02359 ENOG4107BJW polysaccharide deacetylase KAB07_02364 ENOG4105E2S oxidase) subunit II KAB07_02365 ENOG4105BZ9 Cytochrome C oxidase, subunit I KAB07_02366 ENOG4105CCU oxidase (Subunit III) KAB07_02367 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) KAB07_02372 ENOG4105CDU Replicative dna helicase KAB07_02373 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) KAB07_02383 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) KAB07_02384 ENOG4105DC1 bifunctional purine biosynthesis protein purh KAB07_02385 ENOG4105C12 Phosphoribosylglycinamide synthetase KAB07_02387 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) KAB07_02388 ENOG4108UMI ABC transporter, permease KAB07_02389 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) KAB07_02391 ENOG4105CK2 sodium dicarboxylate symporter KAB07_02395 ENOG4105CK2 sodium dicarboxylate symporter KAB07_02422 ENOG4105DY2 Paraquat-inducible protein b KAB07_02423 ENOG4105F1S paraquat-inducible protein a KAB07_02426 ENOG4105CEB Aspartate aminotransferase KAB07_02429 ENOG4105CSH Transporter KAB07_02439 ENOG4105JXH GntR family transcriptional regulator KAB07_02441 ENOG4105D6U Sodium Glutamate Symporter KAB07_02447 ENOG4105H4F exported protein KAB07_02454 ENOG4105C26 Dehydrogenase KAB07_02455 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) KAB07_02456 ENOG4105EVZ LysR family transcriptional regulator KAB07_02461 ENOG4105D9P serine threonine protein kinase KAB07_02466 ENOG4105VCC 30S ribosomal protein S21 KAB07_02467 ENOG4105KTH gatB Yqey KAB07_02468 ENOG4105ERG peptidase m48, ste24p KAB07_02469 ENOG4105C5I Dehydrogenase KAB07_02472 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase KAB07_02479 ENOG41069NU Nitroreductase KAB07_02481 ENOG4105C1J atp-dependent rna helicase KAB07_02482 ENOG4105VEQ Cold shock protein KAB07_02484 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) KAB07_02485 ENOG4105M08 Membrane KAB07_02491 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) KAB07_02492 ENOG4105CIN aminoacyl-histidine dipeptidase KAB07_02494 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase KAB07_02495 ENOG4105CQC Prephenate dehydratase KAB07_02496 ENOG4105NIV Esterase KAB07_02497 ENOG4105C1G acyl-Coa dehydrogenase KAB07_02498 ENOG4105CK2 sodium dicarboxylate symporter KAB07_02499 ENOG4107QYG anthranilate phosphoribosyltransferase KAB07_02500 ENOG4105VUT cytoplasmic protein KAB07_02501 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) KAB07_02502 ENOG4105BZ4 penicillin-binding protein KAB07_02504 ENOG4105M6F mutator MutT protein KAB07_02506 ENOG4105DHQ Histidine kinase KAB07_02507 ENOG4105XJC Two component transcriptional regulator (Winged helix family KAB07_02509 ENOG4107QHF type ii secretion system protein e KAB07_02511 ENOG4108R96 Methyltransferase, YaeB family KAB07_02512 ENOG4105DP0 ferredoxin-NADP reductase KAB07_02513 ENOG4105JAB phenazine biosynthesis protein, phzf family KAB07_02514 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family KAB07_02515 ENOG4105CFP Peptidase U32 KAB07_02516 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding KAB07_02518 ENOG4108JEH abc transporter atp-binding protein KAB07_02519 ENOG4106YG3 ABC transporter KAB07_02520 ENOG4105DSP amino acid AbC transporter KAB07_02521 ENOG4105E89 ABC transporter KAB07_02523 ENOG4105ENT Efflux transporter rnd family, mfp subunit KAB07_02525 ENOG4105ENJ RND efflux system, outer membrane lipoprotein KAB07_02532 ENOG4105DA5 (ABC) transporter KAB07_02533 ENOG4105E3A (ABC) transporter KAB07_02536 ENOG4105CNI cell division protein FtsW KAB07_02537 ENOG4105CVE Lytic murein transglycosylase KAB07_02545 ENOG4105CE9 30S ribosomal protein S2 KAB07_02546 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) KAB07_02548 ENOG4107RNU major facilitator superfamily MFS_1 KAB07_02551 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) KAB07_02552 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) KAB07_02553 ENOG4107QPN acyl-Coa dehydrogenase KAB07_02556 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) KAB07_02557 ENOG4105SYT Methylenetetrahydrofolate reductase KAB07_02558 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) KAB07_02559 ENOG4105BZU Histidine kinase KAB07_02560 ENOG4105C6K Malic enzyme KAB07_02562 ENOG4105C0H protease KAB07_02563 ENOG4107QNR UPF0135 protein KAB07_02564 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) KAB07_02571 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) KAB07_02573 ENOG4105C5F glutamine synthetase KAB07_02574 ENOG4105DUX Transporter KAB07_02576 ENOG4105DFP Integrase KAB07_02666 ENOG4105DR5 peptidase KAB07_02733 ENOG4105DDQ anthranilate synthase KAB07_02734 ENOG4105CD8 aminopeptidase N KAB07_02740 ENOG4105C7W Xanthine dehydrogenase KAB07_02742 ENOG4105EUJ GTP cyclohydrolase i KAB07_02748 ENOG4105NX3 Membrane KAB07_02751 ENOG4105E4F Isochorismate synthase KAB07_02755 ENOG4105BZ1 (ABC) transporter KAB07_02758 ENOG4105WQI isochorismatase KAB07_02759 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase KAB07_02760 ENOG4105C0W non-ribosomal peptide synthetase KAB07_02764 ENOG4108IPW abc transporter atp-binding protein KAB07_02769 ENOG4105CEY Amp-dependent synthetase and ligase KAB07_02772 ENOG4105WWK YheO domain protein KAB07_02775 ENOG4105C2I pirin domain protein KAB07_02778 ENOG4105J7D transcriptional regulator KAB07_02780 ENOG4107WEA mandelate racemase muconate lactonizing KAB07_02781 ENOG4107QNK )-transporter KAB07_02782 ENOG41060M8 Pfam:PhdYeFM KAB07_02788 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) KAB07_02789 ENOG4107QZF nitrite reductase NADPH large subunit KAB07_02790 ENOG4105C26 Dehydrogenase KAB07_02792 ENOG4105C94 Transporter KAB07_02793 ENOG4105C94 Transporter KAB07_02794 ENOG4105ETT transcriptional Regulator, LysR family KAB07_02795 ENOG4105C85 amino acid KAB07_02796 ENOG4105C26 Dehydrogenase KAB07_02799 ENOG4108K8K Transcriptional regulator KAB07_02806 ENOG4105VCD cytoplasmic protein KAB07_02807 ENOG4105D22 carbon starvation protein KAB07_02809 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein KAB07_02813 ENOG4105DHU Bile acid KAB07_02816 ENOG4105DAN ATP-dependent protease KAB07_02817 ENOG4105EJC lysr family transcriptional regulator KAB07_02818 ENOG4108K5P (LipO)protein KAB07_02822 ENOG4105DZ1 carboxypeptidase KAB07_02823 ENOG4108Z0R Transferase KAB07_02827 ENOG4107QTF adenylosuccinate lyase KAB07_02830 ENOG4105ERU peptidase KAB07_02831 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) KAB07_02833 ENOG4105C8U phosphate abc transporter KAB07_02834 ENOG4105CVA phosphate KAB07_02835 ENOG4105C85 amino acid KAB07_02836 ENOG4107RA9 decarboxylase KAB07_02837 ENOG4105F7P transcriptional regulator AsnC family KAB07_02839 ENOG4105DY8 decarboxylase KAB07_02840 ENOG4108JPW Aminotransferase KAB07_02845 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) KAB07_02851 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) KAB07_02852 ENOG4105D3G Pseudouridine synthase KAB07_02855 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) KAB07_02861 ENOG4105JAB phenazine biosynthesis protein, phzf family KAB07_02862 ENOG4108ETY sodium dicarboxylate symporter KAB07_02863 ENOG4105EGI Transcriptional regulator KAB07_02864 ENOG4105CBP Major Facilitator KAB07_02868 ENOG4108R99 pseudouridine synthase KAB07_02869 ENOG4105E9K Isocitrate dehydrogenase KAB07_02871 ENOG4105DZ1 carboxypeptidase KAB07_02872 ENOG4105CEP NADH dehydrogenase KAB07_02873 ENOG4108YZY peptidylprolyl cis-trans isomerase KAB07_02874 ENOG4105CVP deoxyribo-dipyrimidine photolyase KAB07_02877 ENOG4107R8N Glycosyl transferase, family 2 KAB07_02883 ENOG4105EA8 2-Nitropropane dioxygenase KAB07_02884 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) KAB07_02885 ENOG4107QS8 (LipO)protein KAB07_02893 ENOG4105DTR rard protein KAB07_02895 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) KAB07_02897 ENOG4105BZU Histidine kinase KAB07_02904 ENOG4105EMU Dehydrogenase KAB07_02905 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase KAB07_02906 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) KAB07_02907 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) KAB07_02909 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) KAB07_02912 ENOG4105C3F Signal peptidase i KAB07_02915 ENOG4105C0H protease KAB07_02916 ENOG4108IYU L-aspartate oxidase KAB07_02919 ENOG4105HHA aminodeoxychorismate lyase KAB07_02920 ENOG4105YAZ 4-amino-4-deoxychorismate lyase KAB07_02921 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein KAB07_02923 ENOG4108I5D sulfate abc transporter KAB07_02925 ENOG4108IJ6 ABC transporter KAB07_02926 ENOG4107R11 Transcriptional regulator KAB07_02929 ENOG4107VRB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) KAB07_02930 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) KAB07_02934 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen KAB07_02937 ENOG4108UKI Enoyl-CoA hydratase KAB07_02938 ENOG4105EGD dinuclear metal center protein, YbgI family KAB07_02940 ENOG4105C2C drug resistance transporter, Bcr CflA KAB07_02941 ENOG4108ETH Formylglycinamide ribotide synthetase KAB07_02945 ENOG4105CH2 amidohydrolase KAB07_02946 ENOG4107YD3 Thioesterase KAB07_02947 ENOG4105E02 MotA TolQ exbB proton channel KAB07_02948 ENOG4105M8F Biopolymer transport protein exbD tolR KAB07_02950 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) KAB07_02951 ENOG4105KCK Peptidoglycan-associated lipoprotein KAB07_02964 ENOG4105C02 permease KAB07_02966 ENOG4108V3E phosphoribosylglycinamide formyltransferase KAB07_02967 ENOG4107R6F Alpha Beta Hydrolase Fold protein KAB07_02968 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) KAB07_02970 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 KAB07_02971 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) KAB07_02972 ENOG4105D60 lipoprotein releasing system transmembrane protein KAB07_02979 ENOG4107KET secretion protein, HlyD family KAB07_02986 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) KAB07_02987 ENOG4105C10 Electron transfer flavoprotein KAB07_02988 ENOG4105BZJ Electron transfer flavoprotein KAB07_02989 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) KAB07_02990 ENOG4105N14 lysine exporter protein LysE YggA KAB07_02992 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) KAB07_02994 ENOG4105C85 amino acid KAB07_02995 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) KAB07_02997 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) KAB07_03000 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) KAB07_03001 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit KAB07_03002 ENOG4105BZW Glycerate kinase KAB07_03024 ENOG4105EFV Major head subunit KAB07_03027 ENOG4107XYH virion morphogenesis protein KAB07_03028 ENOG4108QUU Morphogenesis Protein KAB07_03029 ENOG4105QIB mu-like prophage Flumu protein gp29 KAB07_03032 ENOG4105CF2 Mu-like prophage FluMu protein GP28 KAB07_03051 ENOG4105K70 DNA-binding protein KAB07_03059 ENOG4105CEY Amp-dependent synthetase and ligase KAB07_03062 ENOG4108RRZ Transcription elongation factor GreB KAB07_03066 ENOG4105E4C Lytic transglycosylase catalytic KAB07_03069 ENOG4105BZS acriflavin resistance protein KAB07_03070 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase KAB07_03072 ENOG41080IJ Diacylglycerol kinase KAB07_03076 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) KAB07_03079 ENOG4105C6V Glycerol-3-phosphate dehydrogenase KAB07_03080 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) KAB07_03081 ENOG4105CSH Transporter KAB07_03091 ENOG4105EEI dihydropteroate synthase KAB07_03092 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) KAB07_03094 ENOG4105HBR Rna-binding protein KAB07_03097 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain KAB07_03098 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain KAB07_03101 ENOG41080TK Universal stress protein KAB07_03104 ENOG4105PNM synthesis protein KAB07_03108 ENOG4105EEQ Na H antiporter KAB07_03109 ENOG4105CGZ zinc metallopeptidase KAB07_03110 ENOG4105CKW Inner membrane protein yedI KAB07_03112 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha KAB07_03114 ENOG4107QN2 dihydrolipoyl dehydrogenase KAB07_03115 ENOG4105C7S Dehydrogenase KAB07_03116 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 KAB07_03117 ENOG4105E33 succinate dehydrogenase KAB07_03119 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein KAB07_03120 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit KAB07_03127 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) KAB07_03128 ENOG41084BA UPF0250 protein KAB07_03129 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) KAB07_03132 ENOG4105CUB amino acid KAB07_03134 ENOG4105KVH Transcriptional regulator KAB07_03135 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) KAB07_03136 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) KAB07_03139 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) KAB07_03144 ENOG410841Q phosphoesterase PA-phosphatase related protein KAB07_03145 ENOG4105C1P efflux transporter, rnd family, mfp subunit KAB07_03146 ENOG4105BZS acriflavin resistance protein KAB07_03147 ENOG4105ENJ RND efflux system, outer membrane lipoprotein KAB07_03148 ENOG4105K8R UPF0145 protein KAB07_03149 ENOG4105K8R UPF0145 protein KAB07_03153 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) KAB07_03158 ENOG4108M0I Transcriptional regulator KAB07_03161 ENOG4105DHQ Histidine kinase KAB07_03162 ENOG4105XJC Two component transcriptional regulator (Winged helix family KAB07_03163 ENOG4105DIJ Phosphoethanolamine transferase KAB07_03167 ENOG4105D78 K07001 NTE family protein KAB07_03170 ENOG4105MSB protein, conserved in bacteria KAB07_03171 ENOG4105CTB Polyprenyl synthetase KAB07_03172 ENOG4105C7F AcnD-accessory protein PrpF KAB07_03173 ENOG4105C85 amino acid KAB07_03177 ENOG4105CF7 AraC family transcriptional regulator KAB07_03182 ENOG4108X0B nad(p)h dehydrogenase (quinone) KAB07_03184 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein KAB07_03186 ENOG4105D8T Acyltransferase KAB07_03188 ENOG4105C03 ribonuclease KAB07_03189 ENOG4108Z03 MAF-like protein KAB07_03190 ENOG4105VQ7 Rod shape-determining protein MreD KAB07_03191 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) KAB07_03192 ENOG4105DFF Rod shape-determining protein mreb KAB07_03193 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) KAB07_03195 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) KAB07_03202 ENOG4105C7B Threonine dehydratase KAB07_03203 ENOG4105D78 K07001 NTE family protein KAB07_03204 ENOG4105BZG amino acid carrier protein KAB07_03207 ENOG4105C2C drug resistance transporter, Bcr CflA KAB07_03208 ENOG4105EM2 membrane KAB07_03210 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) KAB07_03218 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein KAB07_03219 ENOG4105WD1 Membrane KAB07_03221 ENOG4106HKS Entericidin EcnA/B family KAB07_03224 ENOG4105CBS Chea signal transduction histidine kinase KAB07_03225 ENOG4105C8Q Methyl-accepting chemotaxis KAB07_03226 ENOG4108ZGA chew protein KAB07_03227 ENOG4105M3Z response regulator KAB07_03228 ENOG4108UNF response regulator KAB07_03233 ENOG4105KWI UPF0339 protein KAB07_03234 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA KAB07_03235 ENOG4105K78 MarR family Transcriptional regulator KAB07_03237 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) KAB07_03238 ENOG4105T95 Thiol disulfide interChange protein KAB07_03241 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase KAB07_03242 ENOG4105CHB tonB-dependent Receptor KAB07_03245 ENOG4105CHB tonB-dependent Receptor KAB07_03246 ENOG4108VX5 3-methyladenine DNA glycosylase KAB07_03248 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) KAB07_03252 ENOG4105C2W permease KAB07_03254 ENOG4108IQI permease KAB07_03255 ENOG4105E0Y RtcB Protein KAB07_03257 ENOG4108WHA ompa motb domain protein KAB07_03259 ENOG4105CHU acetyl-coa acetyltransferase KAB07_03263 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) KAB07_03264 ENOG4105DZG Dehydrogenase KAB07_03265 ENOG4105TW1 Carbohydrate-selective porin OprB KAB07_03267 ENOG4108R6W Transcriptional regulator, ARAC family KAB07_03268 ENOG4105CHU acetyl-coa acetyltransferase KAB07_03275 ENOG4108UT2 hemolysin iii KAB07_03276 ENOG4105CSH Transporter KAB07_03279 ENOG4105D3R alkyl hydroperoxide reductase KAB07_03283 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase KAB07_03290 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) KAB07_03293 ENOG4108WBT adenosyltransferase KAB07_03297 ENOG4105CNG UPF0061 protein KAB07_03298 ENOG4105E3W Two component transcriptional regulator (Winged helix family KAB07_03299 ENOG4105EB3 Histidine kinase KAB07_03301 ENOG4105CSU acyl-Coa dehydrogenase KAB07_03302 ENOG4105CSU acyl-Coa dehydrogenase KAB07_03303 ENOG4108R4R Iron-regulated virulence regulatory protein KAB07_03304 ENOG4108K3A Glutathione S-transferase KAB07_03305 ENOG4108VY7 phosphate-starvation-inducible protein PsiE KAB07_03309 ENOG4105UGU tonB-dependent Receptor KAB07_03319 ENOG4108PQP glycosyl transferase group 1 KAB07_03321 ENOG4107BJW polysaccharide deacetylase KAB07_03324 ENOG4105CM2 brancheD-chain amino acid aminotransferase KAB07_03325 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) KAB07_03326 ENOG4105BZU Histidine kinase KAB07_03332 ENOG4105VIE preprotein translocase, subunit YajC KAB07_03333 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) KAB07_03334 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) KAB07_03335 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase KAB07_03337 ENOG4105FFC UPF0187 protein KAB07_03338 ENOG4105DB7 PHP domain protein KAB07_03340 ENOG4105K9H YciI-like protein KAB07_03346 ENOG4105NAU thioesterase Superfamily protein KAB07_03348 ENOG4107U2T alpha beta KAB07_03349 ENOG4107QPB Beta-lactamase domain protein KAB07_03351 ENOG4107QN2 dihydrolipoyl dehydrogenase KAB07_03358 ENOG4108KHX Diguanylate cyclase KAB07_03359 ENOG4105UYK outer membrane protein a KAB07_03361 ENOG4107RZC phospholipase d KAB07_03363 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) KAB07_03367 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) KAB07_03368 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) KAB07_03369 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) KAB07_03371 ENOG4108UJD 30S ribosomal protein S9 KAB07_03372 ENOG4107MKT Stringent starvation protein a KAB07_03373 ENOG4105KB2 stringent starvation protein b KAB07_03377 ENOG4105C1G acyl-Coa dehydrogenase KAB07_03378 ENOG4107QX3 carboxylase KAB07_03381 ENOG4108RZE Tetr family transcriptional regulator KAB07_03382 ENOG4105C1G acyl-Coa dehydrogenase KAB07_03391 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase KAB07_03392 ENOG4105D6S protein involved in catabolism of external DNA KAB07_03398 ENOG4105E4C Lytic transglycosylase catalytic KAB07_03400 ENOG4105C9A Phoh family KAB07_03406 ENOG4105CS1 NAD(P)H quinone oxidoreductase KAB07_03407 ENOG4107S2Z UPF0761 membrane protein KAB07_03409 ENOG4108K2B transcriptional regulator KAB07_03410 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase KAB07_03419 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) KAB07_03420 ENOG4105DGW oligopeptidase A KAB07_03421 ENOG4105VKU nucleicacid-binding protein KAB07_03429 ENOG4105C1G acyl-Coa dehydrogenase KAB07_03434 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) KAB07_03436 ENOG41067V7 50S ribosomal protein L36 KAB07_03437 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) KAB07_03459 ENOG41089BK Glutamine amido-transferase KAB07_03460 ENOG4105C28 cystathionine KAB07_03461 ENOG4105D7A ATP-binding protein KAB07_03463 ENOG4105KPV Transcriptional regulator KAB07_03466 ENOG4105CK2 sodium dicarboxylate symporter KAB07_03467 ENOG4105C29 acyl-CoA thioesterase KAB07_03471 ENOG4105CB5 ATP-dependent DNA helicase recG KAB07_03472 ENOG4105MJ2 Competence protein KAB07_03474 ENOG4108URH decarboxylase KAB07_03475 ENOG4105D7N magnesium and cobalt transport protein CorA KAB07_03477 ENOG4105E3I toluene tolerance KAB07_03479 ENOG4105CY3 ABC transporter, permease KAB07_03480 ENOG4105DHJ ABC, transporter KAB07_03481 ENOG4105C1J atp-dependent rna helicase KAB07_03482 ENOG4105ECY inositol monophosphatase KAB07_03485 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) KAB07_03488 ENOG4105CSU acyl-Coa dehydrogenase KAB07_03490 ENOG41067S9 phage shock protein C, PspC KAB07_03491 ENOG4105W87 Cbs domain KAB07_03503 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin KAB07_03508 ENOG4105C26 Dehydrogenase KAB07_03510 ENOG4105C8Y Acetylornithine aminotransferase KAB07_03511 ENOG4105D82 Glutamate dehydrogenase KAB07_03512 ENOG4108IQI permease KAB07_03519 ENOG4105IPI Membrane KAB07_03520 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) KAB07_03521 ENOG4105EM2 membrane KAB07_03522 ENOG4107QF7 multi-drug KAB07_03524 ENOG4105NF4 modulator of drug activity KAB07_03525 ENOG4105VRH Antibiotic biosynthesis monooxygenase KAB07_03527 ENOG4105CQB FAD linked oxidase domain protein KAB07_03528 ENOG4108JQ1 Dehydrogenase KAB07_03533 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) KAB07_03534 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) KAB07_03535 ENOG4107IFA Lipase (EC 3.1.1.3) KAB07_03538 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) KAB07_03548 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) KAB07_03550 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) KAB07_03551 ENOG4105KME endoribonuclease L-psp KAB07_03553 ENOG4108UQY Iron-storage protein KAB07_03554 ENOG4108YSG O-Antigen polymerase KAB07_03558 ENOG4105HA9 of methanol dehydrogenase type KAB07_03559 ENOG4108V0P LemA family KAB07_03561 ENOG4105BZ8 glutamate synthase KAB07_03562 ENOG4105CBC glutamate synthase KAB07_03566 ENOG4105E4G Type IV pilus KAB07_03571 ENOG4108JQC penicillin-binding protein 1A KAB07_03572 ENOG4105DHI Methyltransferase KAB07_03575 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) KAB07_03576 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) KAB07_03577 ENOG4105CJN penicillin-binding protein KAB07_03580 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein KAB07_03585 ENOG4108IQI permease KAB07_03601 ENOG4105C5H ABC transporter KAB07_03603 ENOG4105PDP Short chain dehydrogenase KAB07_03604 ENOG4105CHH sulfate transporter KAB07_03606 ENOG4105DPZ Two component transcriptional regulator (Winged helix family KAB07_03607 ENOG4105E0F Histidine kinase KAB07_03608 ENOG4105CYC Transferase KAB07_03614 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) KAB07_03620 ENOG41061CK Antibiotic biosynthesis monooxygenase KAB07_03623 ENOG4105CUV Homoserine Kinase KAB07_03636 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein KAB07_03637 ENOG4105KVH Transcriptional regulator KAB07_03642 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) KAB07_03643 ENOG4105CPC Aldo Keto reductase KAB07_03647 ENOG4106NZI LysR family Transcriptional regulator KAB07_03648 ENOG4105D94 Major Facilitator Superfamily KAB07_03654 ENOG4105EUB pirin domain protein KAB07_03655 ENOG4105CHJ isochorismatase hydrolase KAB07_03657 ENOG4105C26 Dehydrogenase KAB07_03658 ENOG4108JPW Aminotransferase KAB07_03660 ENOG4105C85 amino acid KAB07_03662 ENOG4108UMN azlc family KAB07_03664 ENOG4108UUM single-stranded DNA-binding protein KAB07_03666 ENOG4107RDB Major Facilitator KAB07_03668 ENOG4105DWF phosphomethylpyrimidine kinase KAB07_03669 ENOG4105RA2 Membrane KAB07_03671 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein KAB07_03672 ENOG4108WUH Transcriptional regulator, TetR family KAB07_03673 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) KAB07_03675 ENOG4105BZU Histidine kinase KAB07_03677 ENOG4105C94 Transporter KAB07_03679 ENOG4107QN1 sodium solute KAB07_03680 ENOG41062QD Membrane KAB07_03681 ENOG4105BZU Histidine kinase KAB07_03684 ENOG4108UZX fmn reductase KAB07_03685 ENOG4105FBW Monooxygenase KAB07_03686 ENOG4105D5G Transposase KAB07_03688 ENOG4108W2Y isochorismatase KAB07_03689 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) KAB07_03691 ENOG4105D64 Mechanosensitive ion channel KAB07_03693 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase KAB07_03694 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase KAB07_03697 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) KAB07_03699 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) KAB07_03702 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) KAB07_03705 ENOG4105E0K tonB-dependent siderophore receptor KAB07_03708 ENOG4107QSN dihydrolipoamide acetyltransferase KAB07_03709 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) KAB07_03710 ENOG41063SB peptidase KAB07_03713 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) KAB07_03714 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) KAB07_03715 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) KAB07_03719 ENOG4105D7Z glutathione synthase KAB07_03723 ENOG4105CGK Exodeoxyribonuclease III KAB07_03724 ENOG4105KUZ arsenate reductase KAB07_03727 ENOG4105BZU Histidine kinase KAB07_03728 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) KAB07_03734 ENOG41084YZ Hydrolase KAB07_03737 ENOG41061H0 Monooxygenase KAB07_03739 ENOG4108Z2U ureidoglycolate hydrolase KAB07_03740 ENOG4105EWI Short-chain dehydrogenase reductase Sdr KAB07_03741 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) KAB07_03742 ENOG4105IPS esterase KAB07_03745 ENOG4105K4H Nlp p60 protein KAB07_03746 ENOG4105CS6 Rhs element vgr protein KAB07_03748 ENOG4105D9M gamma-glutamylcysteine synthetase KAB07_03751 ENOG4106BRA Membrane KAB07_03752 ENOG4105CHM Aminotransferase KAB07_03753 ENOG4107QJQ Mate efflux family protein KAB07_03756 ENOG4105CK6 Two component transcriptional regulator (Winged helix family KAB07_03757 ENOG4105BZU Histidine kinase KAB07_03763 ENOG4105KHC sulfurtransferase KAB07_03770 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) KAB07_03773 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) KAB07_03774 ENOG4108ZAI phosphatidylglycerophosphatase a KAB07_03776 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) KAB07_03777 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) KAB07_03780 ENOG41088SP formiminoglutamate hydrolase KAB07_03782 ENOG4105C85 amino acid KAB07_03785 ENOG41090B9 response to stress KAB07_03786 ENOG4105CZE histidine utilization repressor KAB07_03788 ENOG4105CKI cobalamin synthesis protein KAB07_03790 ENOG4105C85 amino acid KAB07_03792 ENOG4108RXX maleylacetoacetate isomerase KAB07_03796 ENOG4105EWC Purine nucleoside phosphorylase KAB07_03797 ENOG4107QI1 Mate efflux family protein KAB07_03798 ENOG4105C09 Bile acid KAB07_03799 ENOG4108RWI nicotinamidase KAB07_03800 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) KAB07_03804 ENOG4105S64 Formate nitrite transporter KAB07_03805 ENOG4105D1H recombination factor protein RarA KAB07_03807 ENOG4108ZZ3 UPF0260 protein KAB07_03811 ENOG4105CEN a g-specific adenine glycosylase KAB07_03814 ENOG4108R3E Dna-3-methyladenine glycosylase i KAB07_03815 ENOG4105DQ4 alcohol dehydrogenase KAB07_03818 ENOG4105HEI LysR family (Transcriptional regulator KAB07_03819 ENOG4105CV8 reductase KAB07_03820 ENOG4105F27 Major Facilitator KAB07_03827 ENOG4105DJY efflux transporter, rnd family, mfp subunit KAB07_03828 ENOG4108IG5 Transcriptional regulator KAB07_03830 ENOG4105C2W permease KAB07_03836 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B KAB07_03840 ENOG4105C8J )-transporter KAB07_03848 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) KAB07_03849 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) KAB07_03850 ENOG4105D74 hydrolase KAB07_03852 ENOG4108821 RND type efflux pump KAB07_03853 ENOG4108821 RND type efflux pump KAB07_03854 ENOG4108821 RND type efflux pump KAB07_03856 ENOG4105K5T PilT protein KAB07_03863 ENOG4105T95 Thiol disulfide interChange protein KAB07_03879 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) KAB07_03897 ENOG4105KK6 nuclease KAB07_03898 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS KAB07_03910 ENOG4105FA0 parb-like partition protein KAB07_03914 ENOG4105CDW Resistance protein KAB07_03934 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)