locus-tag class description KBNAB1_0002 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) KBNAB1_0004 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) KBNAB1_0006 ENOG4105DQR SNARE associated Golgi KBNAB1_0007 ENOG4105C5H ABC transporter KBNAB1_0008 ENOG4108821 RND type efflux pump KBNAB1_0009 ENOG4108821 RND type efflux pump KBNAB1_0010 ENOG4108821 RND type efflux pump KBNAB1_0012 ENOG4105D74 hydrolase KBNAB1_0013 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) KBNAB1_0014 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) KBNAB1_0021 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B KBNAB1_0027 ENOG4105C2W permease KBNAB1_0029 ENOG4108IG5 Transcriptional regulator KBNAB1_0030 ENOG4105DJY efflux transporter, rnd family, mfp subunit KBNAB1_0037 ENOG4105F27 Major Facilitator KBNAB1_0038 ENOG4105CV8 reductase KBNAB1_0039 ENOG4105HEI LysR family (Transcriptional regulator KBNAB1_0042 ENOG4105DQ4 alcohol dehydrogenase KBNAB1_0043 ENOG4108R3E Dna-3-methyladenine glycosylase i KBNAB1_0046 ENOG4105CEN a g-specific adenine glycosylase KBNAB1_0050 ENOG4108ZZ3 UPF0260 protein KBNAB1_0052 ENOG4105D1H recombination factor protein RarA KBNAB1_0053 ENOG4105S64 Formate nitrite transporter KBNAB1_0057 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) KBNAB1_0058 ENOG4108RWI nicotinamidase KBNAB1_0059 ENOG4105C09 Bile acid KBNAB1_0060 ENOG4107QI1 Mate efflux family protein KBNAB1_0061 ENOG4105EWC Purine nucleoside phosphorylase KBNAB1_0065 ENOG4108RXX maleylacetoacetate isomerase KBNAB1_0067 ENOG4105C85 amino acid KBNAB1_0069 ENOG4105CKI cobalamin synthesis protein KBNAB1_0071 ENOG4105CZE histidine utilization repressor KBNAB1_0072 ENOG41090B9 response to stress KBNAB1_0075 ENOG4105C85 amino acid KBNAB1_0077 ENOG41088SP formiminoglutamate hydrolase KBNAB1_0080 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) KBNAB1_0081 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) KBNAB1_0083 ENOG4108ZAI phosphatidylglycerophosphatase a KBNAB1_0084 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) KBNAB1_0087 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) KBNAB1_0094 ENOG4105KHC sulfurtransferase KBNAB1_0100 ENOG4105BZU Histidine kinase KBNAB1_0101 ENOG4105CK6 Two component transcriptional regulator (Winged helix family KBNAB1_0104 ENOG4107QJQ Mate efflux family protein KBNAB1_0105 ENOG4105CHM Aminotransferase KBNAB1_0106 ENOG4106BRA Membrane KBNAB1_0109 ENOG4105D9M gamma-glutamylcysteine synthetase KBNAB1_0111 ENOG4105CS6 Rhs element vgr protein KBNAB1_0116 ENOG4105IPS esterase KBNAB1_0117 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) KBNAB1_0118 ENOG4105EWI Short-chain dehydrogenase reductase Sdr KBNAB1_0119 ENOG4108Z2U ureidoglycolate hydrolase KBNAB1_0121 ENOG41061H0 Monooxygenase KBNAB1_0124 ENOG41084YZ Hydrolase KBNAB1_0130 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) KBNAB1_0131 ENOG4105BZU Histidine kinase KBNAB1_0134 ENOG4105KUZ arsenate reductase KBNAB1_0135 ENOG4105CGK Exodeoxyribonuclease III KBNAB1_0139 ENOG4105D7Z glutathione synthase KBNAB1_0143 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) KBNAB1_0144 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) KBNAB1_0145 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) KBNAB1_0148 ENOG41063SB peptidase KBNAB1_0149 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) KBNAB1_0150 ENOG4107QSN dihydrolipoamide acetyltransferase KBNAB1_0153 ENOG4105E0K tonB-dependent siderophore receptor KBNAB1_0156 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) KBNAB1_0159 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) KBNAB1_0161 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) KBNAB1_0164 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase KBNAB1_0165 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase KBNAB1_0167 ENOG4105D64 Mechanosensitive ion channel KBNAB1_0169 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) KBNAB1_0170 ENOG4108W2Y isochorismatase KBNAB1_0172 ENOG4105D5G Transposase KBNAB1_0173 ENOG4105FBW Monooxygenase KBNAB1_0174 ENOG4108UZX fmn reductase KBNAB1_0177 ENOG4105BZU Histidine kinase KBNAB1_0178 ENOG41062QD Membrane KBNAB1_0179 ENOG4107QN1 sodium solute KBNAB1_0181 ENOG4105C94 Transporter KBNAB1_0183 ENOG4105BZU Histidine kinase KBNAB1_0185 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) KBNAB1_0186 ENOG4108WUH Transcriptional regulator, TetR family KBNAB1_0187 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein KBNAB1_0189 ENOG4105RA2 Membrane KBNAB1_0190 ENOG4105DWF phosphomethylpyrimidine kinase KBNAB1_0192 ENOG4107RDB Major Facilitator KBNAB1_0193 ENOG4108UUM single-stranded DNA-binding protein KBNAB1_0195 ENOG4108UMN azlc family KBNAB1_0197 ENOG4105C85 amino acid KBNAB1_0199 ENOG4108JPW Aminotransferase KBNAB1_0200 ENOG4105C26 Dehydrogenase KBNAB1_0202 ENOG4105CHJ isochorismatase hydrolase KBNAB1_0203 ENOG4105EUB pirin domain protein KBNAB1_0208 ENOG4105D94 Major Facilitator Superfamily KBNAB1_0209 ENOG4106NZI LysR family Transcriptional regulator KBNAB1_0213 ENOG4105CPC Aldo Keto reductase KBNAB1_0214 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) KBNAB1_0219 ENOG4105KVH Transcriptional regulator KBNAB1_0220 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein KBNAB1_0232 ENOG4105CUV Homoserine Kinase KBNAB1_0235 ENOG41061CK Antibiotic biosynthesis monooxygenase KBNAB1_0241 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) KBNAB1_0245 ENOG4105CYC Transferase KBNAB1_0246 ENOG4105E0F Histidine kinase KBNAB1_0247 ENOG4105DPZ Two component transcriptional regulator (Winged helix family KBNAB1_0249 ENOG4105CHH sulfate transporter KBNAB1_0250 ENOG4105PDP Short chain dehydrogenase KBNAB1_0252 ENOG4105C5H ABC transporter KBNAB1_0266 ENOG4108IQI permease KBNAB1_0269 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein KBNAB1_0272 ENOG4105CJN penicillin-binding protein KBNAB1_0273 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) KBNAB1_0274 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) KBNAB1_0277 ENOG4105DHI Methyltransferase KBNAB1_0278 ENOG4108JQC penicillin-binding protein 1A KBNAB1_0283 ENOG4105E4G Type IV pilus KBNAB1_0287 ENOG4105CBC glutamate synthase KBNAB1_0288 ENOG4105BZ8 glutamate synthase KBNAB1_0290 ENOG4108V0P LemA family KBNAB1_0291 ENOG4105HA9 of methanol dehydrogenase type KBNAB1_0295 ENOG4108YSG O-Antigen polymerase KBNAB1_0296 ENOG4108UQY Iron-storage protein KBNAB1_0298 ENOG4105KME endoribonuclease L-psp KBNAB1_0299 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) KBNAB1_0301 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) KBNAB1_0311 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) KBNAB1_0314 ENOG4107IFA Lipase (EC 3.1.1.3) KBNAB1_0315 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) KBNAB1_0316 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) KBNAB1_0321 ENOG4108JQ1 Dehydrogenase KBNAB1_0322 ENOG4105CQB FAD linked oxidase domain protein KBNAB1_0324 ENOG4105VRH Antibiotic biosynthesis monooxygenase KBNAB1_0325 ENOG4105NF4 modulator of drug activity KBNAB1_0327 ENOG4107QF7 multi-drug KBNAB1_0328 ENOG4105EM2 membrane KBNAB1_0329 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) KBNAB1_0330 ENOG4105IPI Membrane KBNAB1_0337 ENOG4108IQI permease KBNAB1_0338 ENOG4105D82 Glutamate dehydrogenase KBNAB1_0339 ENOG4105C8Y Acetylornithine aminotransferase KBNAB1_0341 ENOG4105C26 Dehydrogenase KBNAB1_0346 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin KBNAB1_0358 ENOG4105W87 Cbs domain KBNAB1_0359 ENOG41067S9 phage shock protein C, PspC KBNAB1_0361 ENOG4105CSU acyl-Coa dehydrogenase KBNAB1_0364 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) KBNAB1_0367 ENOG4105ECY inositol monophosphatase KBNAB1_0368 ENOG4105C1J atp-dependent rna helicase KBNAB1_0369 ENOG4105DHJ ABC, transporter KBNAB1_0370 ENOG4105CY3 ABC transporter, permease KBNAB1_0372 ENOG4105E3I toluene tolerance KBNAB1_0374 ENOG4105D7N magnesium and cobalt transport protein CorA KBNAB1_0375 ENOG4108URH decarboxylase KBNAB1_0377 ENOG4105MJ2 Competence protein KBNAB1_0378 ENOG4105CB5 ATP-dependent DNA helicase recG KBNAB1_0382 ENOG4105C29 acyl-CoA thioesterase KBNAB1_0383 ENOG4105CK2 sodium dicarboxylate symporter KBNAB1_0386 ENOG4105KPV Transcriptional regulator KBNAB1_0388 ENOG4105D7A ATP-binding protein KBNAB1_0389 ENOG4105C28 cystathionine KBNAB1_0390 ENOG41089BK Glutamine amido-transferase KBNAB1_0412 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) KBNAB1_0415 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) KBNAB1_0420 ENOG4105C1G acyl-Coa dehydrogenase KBNAB1_0428 ENOG4105VKU nucleicacid-binding protein KBNAB1_0429 ENOG4105DGW oligopeptidase A KBNAB1_0430 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) KBNAB1_0435 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase KBNAB1_0436 ENOG4108K2B transcriptional regulator KBNAB1_0438 ENOG4107S2Z UPF0761 membrane protein KBNAB1_0439 ENOG4105CS1 NAD(P)H quinone oxidoreductase KBNAB1_0445 ENOG4105C9A Phoh family KBNAB1_0447 ENOG4105E4C Lytic transglycosylase catalytic KBNAB1_0453 ENOG4105D6S protein involved in catabolism of external DNA KBNAB1_0454 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase KBNAB1_0458 ENOG4105C1G acyl-Coa dehydrogenase KBNAB1_0459 ENOG4108RZE Tetr family transcriptional regulator KBNAB1_0462 ENOG4107QX3 carboxylase KBNAB1_0463 ENOG4105C1G acyl-Coa dehydrogenase KBNAB1_0467 ENOG4105KB2 stringent starvation protein b KBNAB1_0468 ENOG4107MKT Stringent starvation protein a KBNAB1_0469 ENOG4108UJD 30S ribosomal protein S9 KBNAB1_0471 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) KBNAB1_0472 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) KBNAB1_0473 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) KBNAB1_0477 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) KBNAB1_0479 ENOG4107RZC phospholipase d KBNAB1_0481 ENOG4105UYK outer membrane protein a KBNAB1_0482 ENOG4108KHX Diguanylate cyclase KBNAB1_0484 ENOG4107QN2 dihydrolipoyl dehydrogenase KBNAB1_0486 ENOG4107QPB Beta-lactamase domain protein KBNAB1_0487 ENOG4107U2T alpha beta KBNAB1_0489 ENOG4105NAU thioesterase Superfamily protein KBNAB1_0495 ENOG4105K9H YciI-like protein KBNAB1_0497 ENOG4105DB7 PHP domain protein KBNAB1_0498 ENOG4105FFC UPF0187 protein KBNAB1_0500 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase KBNAB1_0501 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) KBNAB1_0502 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) KBNAB1_0503 ENOG4105VIE preprotein translocase, subunit YajC KBNAB1_0508 ENOG4105BZU Histidine kinase KBNAB1_0509 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) KBNAB1_0510 ENOG4105CM2 brancheD-chain amino acid aminotransferase KBNAB1_0513 ENOG4107BJW polysaccharide deacetylase KBNAB1_0515 ENOG4108PQP glycosyl transferase group 1 KBNAB1_0523 ENOG4105UGU tonB-dependent Receptor KBNAB1_0527 ENOG4108VY7 phosphate-starvation-inducible protein PsiE KBNAB1_0528 ENOG4108K3A Glutathione S-transferase KBNAB1_0529 ENOG4108R4R Iron-regulated virulence regulatory protein KBNAB1_0530 ENOG4105CSU acyl-Coa dehydrogenase KBNAB1_0531 ENOG4105CSU acyl-Coa dehydrogenase KBNAB1_0533 ENOG4105EB3 Histidine kinase KBNAB1_0534 ENOG4105E3W Two component transcriptional regulator (Winged helix family KBNAB1_0535 ENOG4105CNG UPF0061 protein KBNAB1_0539 ENOG4108WBT adenosyltransferase KBNAB1_0542 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) KBNAB1_0549 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase KBNAB1_0553 ENOG4105D3R alkyl hydroperoxide reductase KBNAB1_0556 ENOG4105CSH Transporter KBNAB1_0557 ENOG4108UT2 hemolysin iii KBNAB1_0564 ENOG4105CHU acetyl-coa acetyltransferase KBNAB1_0565 ENOG4108R6W Transcriptional regulator, ARAC family KBNAB1_0567 ENOG4105TW1 Carbohydrate-selective porin OprB KBNAB1_0568 ENOG4105DZG Dehydrogenase KBNAB1_0569 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) KBNAB1_0571 ENOG410814C multidrug resistance protein KBNAB1_0573 ENOG4105CHU acetyl-coa acetyltransferase KBNAB1_0575 ENOG4108WHA ompa motb domain protein KBNAB1_0577 ENOG4105E0Y RtcB Protein KBNAB1_0578 ENOG4108IQI permease KBNAB1_0580 ENOG4105C2W permease KBNAB1_0584 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) KBNAB1_0586 ENOG4108VX5 3-methyladenine DNA glycosylase KBNAB1_0587 ENOG4105CHB tonB-dependent Receptor KBNAB1_0590 ENOG4105CHB tonB-dependent Receptor KBNAB1_0591 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase KBNAB1_0592 ENOG4108N2Y auxin Efflux KBNAB1_0594 ENOG4105T95 Thiol disulfide interChange protein KBNAB1_0595 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) KBNAB1_0597 ENOG4105K78 MarR family Transcriptional regulator KBNAB1_0598 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA KBNAB1_0599 ENOG4105KWI UPF0339 protein KBNAB1_0604 ENOG4108UNF response regulator KBNAB1_0605 ENOG4105M3Z response regulator KBNAB1_0606 ENOG4108ZGA chew protein KBNAB1_0607 ENOG4105C8Q Methyl-accepting chemotaxis KBNAB1_0608 ENOG4105CBS Chea signal transduction histidine kinase KBNAB1_0613 ENOG4105WD1 Membrane KBNAB1_0614 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein KBNAB1_0616 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) KBNAB1_0618 ENOG4105EM2 membrane KBNAB1_0619 ENOG4105C2C drug resistance transporter, Bcr CflA KBNAB1_0622 ENOG4105BZG amino acid carrier protein KBNAB1_0623 ENOG4105D78 K07001 NTE family protein KBNAB1_0624 ENOG4105C7B Threonine dehydratase KBNAB1_0631 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) KBNAB1_0633 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) KBNAB1_0634 ENOG4105DFF Rod shape-determining protein mreb KBNAB1_0635 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) KBNAB1_0636 ENOG4105VQ7 Rod shape-determining protein MreD KBNAB1_0637 ENOG4108Z03 MAF-like protein KBNAB1_0638 ENOG4105C03 ribonuclease KBNAB1_0640 ENOG4105D8T Acyltransferase KBNAB1_0642 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein KBNAB1_0644 ENOG4108X0B nad(p)h dehydrogenase (quinone) KBNAB1_0649 ENOG4105CF7 AraC family transcriptional regulator KBNAB1_0652 ENOG4105C85 amino acid KBNAB1_0653 ENOG4105C7F AcnD-accessory protein PrpF KBNAB1_0654 ENOG4105CTB Polyprenyl synthetase KBNAB1_0655 ENOG4105MSB protein, conserved in bacteria KBNAB1_0659 ENOG4105D78 K07001 NTE family protein KBNAB1_0663 ENOG4105DIJ Phosphoethanolamine transferase KBNAB1_0664 ENOG4105XJC Two component transcriptional regulator (Winged helix family KBNAB1_0665 ENOG4105DHQ Histidine kinase KBNAB1_0668 ENOG4108M0I Transcriptional regulator KBNAB1_0672 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) KBNAB1_0676 ENOG4105K8R UPF0145 protein KBNAB1_0677 ENOG4105K8R UPF0145 protein KBNAB1_0678 ENOG4105ENJ RND efflux system, outer membrane lipoprotein KBNAB1_0679 ENOG4105BZS acriflavin resistance protein KBNAB1_0680 ENOG4105C1P efflux transporter, rnd family, mfp subunit KBNAB1_0681 ENOG410841Q phosphoesterase PA-phosphatase related protein KBNAB1_0686 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) KBNAB1_0689 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) KBNAB1_0690 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) KBNAB1_0691 ENOG4105KVH Transcriptional regulator KBNAB1_0693 ENOG4105CUB amino acid KBNAB1_0696 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) KBNAB1_0697 ENOG41084BA UPF0250 protein KBNAB1_0698 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) KBNAB1_0705 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit KBNAB1_0706 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein KBNAB1_0708 ENOG4105E33 succinate dehydrogenase KBNAB1_0709 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 KBNAB1_0710 ENOG4105C7S Dehydrogenase KBNAB1_0711 ENOG4107QN2 dihydrolipoyl dehydrogenase KBNAB1_0713 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha KBNAB1_0715 ENOG4105CKW Inner membrane protein yedI KBNAB1_0716 ENOG4105CGZ zinc metallopeptidase KBNAB1_0717 ENOG4105EEQ Na H antiporter KBNAB1_0721 ENOG4105PNM synthesis protein KBNAB1_0724 ENOG41080TK Universal stress protein KBNAB1_0727 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain KBNAB1_0728 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain KBNAB1_0731 ENOG4105HBR Rna-binding protein KBNAB1_0733 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) KBNAB1_0734 ENOG4105EEI dihydropteroate synthase KBNAB1_0741 ENOG4105CSH Transporter KBNAB1_0742 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) KBNAB1_0743 ENOG4105C6V Glycerol-3-phosphate dehydrogenase KBNAB1_0746 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) KBNAB1_0750 ENOG41080IJ Diacylglycerol kinase KBNAB1_0752 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase KBNAB1_0757 ENOG4105E4C Lytic transglycosylase catalytic KBNAB1_0761 ENOG4108RRZ Transcription elongation factor GreB KBNAB1_0763 ENOG4105CEY Amp-dependent synthetase and ligase KBNAB1_0771 ENOG4105BZW Glycerate kinase KBNAB1_0772 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit KBNAB1_0773 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) KBNAB1_0776 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) KBNAB1_0778 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) KBNAB1_0779 ENOG4105C85 amino acid KBNAB1_0781 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) KBNAB1_0783 ENOG4105N14 lysine exporter protein LysE YggA KBNAB1_0784 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) KBNAB1_0785 ENOG4105BZJ Electron transfer flavoprotein KBNAB1_0786 ENOG4105C10 Electron transfer flavoprotein KBNAB1_0787 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) KBNAB1_0794 ENOG4107KET secretion protein, HlyD family KBNAB1_0801 ENOG4105D60 lipoprotein releasing system transmembrane protein KBNAB1_0802 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) KBNAB1_0803 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 KBNAB1_0805 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) KBNAB1_0806 ENOG4107R6F Alpha Beta Hydrolase Fold protein KBNAB1_0807 ENOG4108V3E phosphoribosylglycinamide formyltransferase KBNAB1_0809 ENOG4105C02 permease KBNAB1_0822 ENOG4105KCK Peptidoglycan-associated lipoprotein KBNAB1_0823 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) KBNAB1_0825 ENOG4105M8F Biopolymer transport protein exbD tolR KBNAB1_0826 ENOG4105E02 MotA TolQ exbB proton channel KBNAB1_0827 ENOG4107YD3 Thioesterase KBNAB1_0828 ENOG4105CH2 amidohydrolase KBNAB1_0832 ENOG4108ETH Formylglycinamide ribotide synthetase KBNAB1_0833 ENOG4105C2C drug resistance transporter, Bcr CflA KBNAB1_0835 ENOG4105EGD dinuclear metal center protein, YbgI family KBNAB1_0836 ENOG4108UKI Enoyl-CoA hydratase KBNAB1_0839 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen KBNAB1_0842 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) KBNAB1_0843 ENOG4107VRB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) KBNAB1_0846 ENOG4107R11 Transcriptional regulator KBNAB1_0847 ENOG4108IJ6 ABC transporter KBNAB1_0849 ENOG4108I5D sulfate abc transporter KBNAB1_0851 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein KBNAB1_0852 ENOG4105YAZ 4-amino-4-deoxychorismate lyase KBNAB1_0853 ENOG4105HHA aminodeoxychorismate lyase KBNAB1_0856 ENOG4108IYU L-aspartate oxidase KBNAB1_0857 ENOG4105C0H protease KBNAB1_0860 ENOG4105C3F Signal peptidase i KBNAB1_0863 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) KBNAB1_0865 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) KBNAB1_0866 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) KBNAB1_0867 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase KBNAB1_0868 ENOG4105EMU Dehydrogenase KBNAB1_0874 ENOG4105BZU Histidine kinase KBNAB1_0876 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) KBNAB1_0878 ENOG4105DTR rard protein KBNAB1_0885 ENOG4107QS8 (LipO)protein KBNAB1_0940 ENOG4105DR5 peptidase KBNAB1_1021 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) KBNAB1_1022 ENOG4105EA8 2-Nitropropane dioxygenase KBNAB1_1028 ENOG4107R8N Glycosyl transferase, family 2 KBNAB1_1031 ENOG4105CVP deoxyribo-dipyrimidine photolyase KBNAB1_1032 ENOG4108YZY peptidylprolyl cis-trans isomerase KBNAB1_1033 ENOG4105CEP NADH dehydrogenase KBNAB1_1034 ENOG4105DZ1 carboxypeptidase KBNAB1_1036 ENOG4105E9K Isocitrate dehydrogenase KBNAB1_1037 ENOG4108R99 pseudouridine synthase KBNAB1_1041 ENOG4105CBP Major Facilitator KBNAB1_1042 ENOG4105EGI Transcriptional regulator KBNAB1_1043 ENOG4108ETY sodium dicarboxylate symporter KBNAB1_1044 ENOG4105JAB phenazine biosynthesis protein, phzf family KBNAB1_1050 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) KBNAB1_1054 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) KBNAB1_1057 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) KBNAB1_1062 ENOG4108JPW Aminotransferase KBNAB1_1063 ENOG4105DY8 decarboxylase KBNAB1_1065 ENOG4105F7P transcriptional regulator AsnC family KBNAB1_1066 ENOG4107RA9 decarboxylase KBNAB1_1067 ENOG4105C85 amino acid KBNAB1_1068 ENOG4105CVA phosphate KBNAB1_1069 ENOG4105C8U phosphate abc transporter KBNAB1_1071 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) KBNAB1_1072 ENOG4105ERU peptidase KBNAB1_1075 ENOG4107QTF adenylosuccinate lyase KBNAB1_1079 ENOG4108Z0R Transferase KBNAB1_1080 ENOG4105DZ1 carboxypeptidase KBNAB1_1084 ENOG4108K5P (LipO)protein KBNAB1_1085 ENOG4105EJC lysr family transcriptional regulator KBNAB1_1086 ENOG4105DAN ATP-dependent protease KBNAB1_1089 ENOG4105DHU Bile acid KBNAB1_1093 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein KBNAB1_1095 ENOG4105D22 carbon starvation protein KBNAB1_1096 ENOG4105VCD cytoplasmic protein KBNAB1_1102 ENOG4108K8K Transcriptional regulator KBNAB1_1105 ENOG4105C26 Dehydrogenase KBNAB1_1106 ENOG4105C85 amino acid KBNAB1_1107 ENOG4105ETT transcriptional Regulator, LysR family KBNAB1_1109 ENOG4105C94 Transporter KBNAB1_1110 ENOG4105C94 Transporter KBNAB1_1112 ENOG4105C26 Dehydrogenase KBNAB1_1113 ENOG4107QZF nitrite reductase NADPH large subunit KBNAB1_1114 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) KBNAB1_1120 ENOG41060M8 Pfam:PhdYeFM KBNAB1_1121 ENOG4107QNK )-transporter KBNAB1_1122 ENOG4107WEA mandelate racemase muconate lactonizing KBNAB1_1124 ENOG4105J7D transcriptional regulator KBNAB1_1127 ENOG4105C2I pirin domain protein KBNAB1_1130 ENOG4105WWK YheO domain protein KBNAB1_1133 ENOG4105CEY Amp-dependent synthetase and ligase KBNAB1_1138 ENOG4108IPW abc transporter atp-binding protein KBNAB1_1142 ENOG4105C0W non-ribosomal peptide synthetase KBNAB1_1143 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase KBNAB1_1144 ENOG4105WQI isochorismatase KBNAB1_1147 ENOG4105BZ1 (ABC) transporter KBNAB1_1151 ENOG4105E4F Isochorismate synthase KBNAB1_1156 ENOG4105NX3 Membrane KBNAB1_1162 ENOG4105EUJ GTP cyclohydrolase i KBNAB1_1164 ENOG4105C7W Xanthine dehydrogenase KBNAB1_1170 ENOG4105CD8 aminopeptidase N KBNAB1_1171 ENOG4105DDQ anthranilate synthase KBNAB1_1173 ENOG4105DUX Transporter KBNAB1_1174 ENOG4105C5F glutamine synthetase KBNAB1_1176 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) KBNAB1_1180 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) KBNAB1_1181 ENOG4107QNR UPF0135 protein KBNAB1_1182 ENOG4105C0H protease KBNAB1_1184 ENOG4105C6K Malic enzyme KBNAB1_1185 ENOG4105BZU Histidine kinase KBNAB1_1186 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) KBNAB1_1187 ENOG4105SYT Methylenetetrahydrofolate reductase KBNAB1_1188 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) KBNAB1_1191 ENOG4107QPN acyl-Coa dehydrogenase KBNAB1_1192 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) KBNAB1_1193 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) KBNAB1_1196 ENOG4107RNU major facilitator superfamily MFS_1 KBNAB1_1198 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) KBNAB1_1199 ENOG4105CE9 30S ribosomal protein S2 KBNAB1_1207 ENOG4105CVE Lytic murein transglycosylase KBNAB1_1208 ENOG4105CNI cell division protein FtsW KBNAB1_1211 ENOG4105E3A (ABC) transporter KBNAB1_1212 ENOG4105DA5 (ABC) transporter KBNAB1_1218 ENOG4105ENJ RND efflux system, outer membrane lipoprotein KBNAB1_1220 ENOG4105ENT Efflux transporter rnd family, mfp subunit KBNAB1_1223 ENOG4105E89 ABC transporter KBNAB1_1224 ENOG4105DSP amino acid AbC transporter KBNAB1_1225 ENOG4106YG3 ABC transporter KBNAB1_1226 ENOG4108JEH abc transporter atp-binding protein KBNAB1_1228 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding KBNAB1_1229 ENOG4105CFP Peptidase U32 KBNAB1_1230 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family KBNAB1_1231 ENOG4105JAB phenazine biosynthesis protein, phzf family KBNAB1_1232 ENOG4105DP0 ferredoxin-NADP reductase KBNAB1_1233 ENOG4108R96 Methyltransferase, YaeB family KBNAB1_1235 ENOG4107QHF type ii secretion system protein e KBNAB1_1237 ENOG4105XJC Two component transcriptional regulator (Winged helix family KBNAB1_1238 ENOG4105DHQ Histidine kinase KBNAB1_1240 ENOG4105M6F mutator MutT protein KBNAB1_1242 ENOG4105BZ4 penicillin-binding protein KBNAB1_1243 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) KBNAB1_1244 ENOG4105VUT cytoplasmic protein KBNAB1_1245 ENOG4107QYG anthranilate phosphoribosyltransferase KBNAB1_1246 ENOG4105CK2 sodium dicarboxylate symporter KBNAB1_1247 ENOG4105C1G acyl-Coa dehydrogenase KBNAB1_1248 ENOG4105NIV Esterase KBNAB1_1249 ENOG4105CQC Prephenate dehydratase KBNAB1_1250 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase KBNAB1_1252 ENOG4105CIN aminoacyl-histidine dipeptidase KBNAB1_1253 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) KBNAB1_1259 ENOG4105M08 Membrane KBNAB1_1260 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) KBNAB1_1262 ENOG4105VEQ Cold shock protein KBNAB1_1265 ENOG41069NU Nitroreductase KBNAB1_1272 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase KBNAB1_1275 ENOG4105C5I Dehydrogenase KBNAB1_1276 ENOG4105ERG peptidase m48, ste24p KBNAB1_1277 ENOG4105KTH gatB Yqey KBNAB1_1278 ENOG4105VCC 30S ribosomal protein S21 KBNAB1_1283 ENOG4105D9P serine threonine protein kinase KBNAB1_1284 ENOG4105EVZ LysR family transcriptional regulator KBNAB1_1285 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) KBNAB1_1286 ENOG4105C26 Dehydrogenase KBNAB1_1293 ENOG4105H4F exported protein KBNAB1_1299 ENOG4105D6U Sodium Glutamate Symporter KBNAB1_1301 ENOG4105JXH GntR family transcriptional regulator KBNAB1_1313 ENOG4108HWY Beta-lactamase KBNAB1_1316 ENOG4107QJE Chromosome Partitioning Protein KBNAB1_1317 ENOG4105ECI YeeC-like protein KBNAB1_1319 ENOG4105F6A helicase KBNAB1_1322 ENOG4105CSH Transporter KBNAB1_1325 ENOG4105CEB Aspartate aminotransferase KBNAB1_1329 ENOG4105F1S paraquat-inducible protein a KBNAB1_1330 ENOG4105DY2 Paraquat-inducible protein b KBNAB1_1360 ENOG4105CK2 sodium dicarboxylate symporter KBNAB1_1366 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) KBNAB1_1367 ENOG4108UMI ABC transporter, permease KBNAB1_1368 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) KBNAB1_1370 ENOG4105C12 Phosphoribosylglycinamide synthetase KBNAB1_1371 ENOG4105DC1 bifunctional purine biosynthesis protein purh KBNAB1_1372 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) KBNAB1_1382 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) KBNAB1_1383 ENOG4105CDU Replicative dna helicase KBNAB1_1388 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) KBNAB1_1389 ENOG4105CCU oxidase (Subunit III) KBNAB1_1390 ENOG4105BZ9 Cytochrome C oxidase, subunit I KBNAB1_1391 ENOG4105E2S oxidase) subunit II KBNAB1_1396 ENOG4107BJW polysaccharide deacetylase KBNAB1_1397 ENOG4105CND Glycosyl transferase, family 2 KBNAB1_1400 ENOG4105DEN Luciferase family KBNAB1_1403 ENOG4105CC0 LysR family Transcriptional regulator KBNAB1_1406 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) KBNAB1_1407 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component KBNAB1_1408 ENOG4105GVF (ABC) transporter KBNAB1_1411 ENOG4105C1G acyl-Coa dehydrogenase KBNAB1_1413 ENOG4108MEJ flavin reductase domain protein KBNAB1_1414 ENOG4105D06 uba thif-type nad fad binding protein KBNAB1_1418 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) KBNAB1_1419 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) KBNAB1_1421 ENOG4105C08 Histidine kinase KBNAB1_1422 ENOG4105EEX Two component transcriptional regulator (Winged helix family KBNAB1_1423 ENOG4105CFQ glutamine synthetase KBNAB1_1426 ENOG4107S74 Lysophospholipid transporter LplT KBNAB1_1427 ENOG4105CFU surface antigen KBNAB1_1430 ENOG4107QIJ Aconitate hydratase 2 KBNAB1_1432 ENOG4105EYW Ion transport protein KBNAB1_1433 ENOG4105F27 Major Facilitator KBNAB1_1436 ENOG4105DZ2 Transcriptional regulator KBNAB1_1443 ENOG4105K8N protein family UPF0079, ATPase KBNAB1_1444 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) KBNAB1_1446 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) KBNAB1_1447 ENOG4108TZV Membrane KBNAB1_1448 ENOG4108RCM Nitroreductase KBNAB1_1450 ENOG4105F10 Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity) KBNAB1_1453 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) KBNAB1_1454 ENOG4107FQ9 ethanolamine ammonia-lyase KBNAB1_1455 ENOG4105CPD ethanolamine ammonia-lyase KBNAB1_1456 ENOG4107R55 ethanolamine transporter KBNAB1_1458 ENOG4107RR1 TRANSCRIPTIONal KBNAB1_1460 ENOG4105C0A alcohol dehydrogenase KBNAB1_1461 ENOG4107QUV Domain protein KBNAB1_1463 ENOG4105F4I Transcriptional regulator KBNAB1_1467 ENOG4105CD8 aminopeptidase N KBNAB1_1469 ENOG4105EMU Dehydrogenase KBNAB1_1471 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) KBNAB1_1472 ENOG4105EW9 transcriptional regulator AsnC family KBNAB1_1474 ENOG4105R8C Transcriptional regulator KBNAB1_1476 ENOG4105CUY Mechanosensitive ion channel KBNAB1_1485 ENOG4105CNM Receptor KBNAB1_1489 ENOG4105C5H ABC transporter KBNAB1_1490 ENOG41081QV Universal stress protein KBNAB1_1495 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic KBNAB1_1497 ENOG4105DKK Benzoate KBNAB1_1498 ENOG4105EW9 transcriptional regulator AsnC family KBNAB1_1499 ENOG4108NIW Leucine export protein LeuE KBNAB1_1500 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) KBNAB1_1501 ENOG4105C5Q Transcriptional regulator KBNAB1_1503 ENOG4105CHU acetyl-coa acetyltransferase KBNAB1_1504 ENOG4105CHR reductase KBNAB1_1509 ENOG4107QMP dna polymerase iii subunits gamma and tau KBNAB1_1511 ENOG4105HSS phospholipase C KBNAB1_1513 ENOG4105C0A alcohol dehydrogenase KBNAB1_1519 ENOG4105CBC glutamate synthase KBNAB1_1578 ENOG4105DR5 peptidase KBNAB1_1645 ENOG4105DR5 peptidase KBNAB1_1660 ENOG4105D8G Major Facilitator superfamily KBNAB1_1662 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase KBNAB1_1663 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein KBNAB1_1667 ENOG4105CK6 Two component transcriptional regulator (Winged helix family KBNAB1_1669 ENOG4107QZF nitrite reductase NADPH large subunit KBNAB1_1670 ENOG4108IFG nitrite reductase, (NAD(P)H) KBNAB1_1674 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) KBNAB1_1677 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) KBNAB1_1678 ENOG4105CVM Molybdenum cofactor synthesis domain protein KBNAB1_1680 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family KBNAB1_1681 ENOG4105T38 integral membrane protein KBNAB1_1685 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) KBNAB1_1686 ENOG4105CMR udp-glucose 4-epimerase KBNAB1_1697 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family KBNAB1_1698 ENOG4105CUX Signal transduction histidine kinase KBNAB1_1702 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) KBNAB1_1703 ENOG4105KNE Phosphatidate cytidylyltransferase KBNAB1_1705 ENOG4105DZP Membrane-associated zinc metalloprotease KBNAB1_1710 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) KBNAB1_1712 ENOG4105Y3E Modulates RecA activity (By similarity) KBNAB1_1714 ENOG4105VEJ Heat shock protein KBNAB1_1715 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 KBNAB1_1720 ENOG4105F7P transcriptional regulator AsnC family KBNAB1_1723 ENOG4105C85 amino acid KBNAB1_1727 ENOG4105CHH sulfate transporter KBNAB1_1728 ENOG4108RAV Conserved protein KBNAB1_1729 ENOG4105D8V Glucose sorbosone dehydrogenase KBNAB1_1731 ENOG4105BZU Histidine kinase KBNAB1_1736 ENOG4105DM4 PTS System KBNAB1_1737 ENOG4105DE4 1-phosphofructokinase KBNAB1_1738 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) KBNAB1_1743 ENOG4105CWM branched-chain amino acid transport system II carrier protein KBNAB1_1744 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) KBNAB1_1745 ENOG4105CC0 LysR family Transcriptional regulator KBNAB1_1747 ENOG4105M2J Glutaredoxin KBNAB1_1748 ENOG4105C8Y Acetylornithine aminotransferase KBNAB1_1749 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) KBNAB1_1754 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) KBNAB1_1756 ENOG41068P6 UPF0319 protein KBNAB1_1760 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii KBNAB1_1761 ENOG4105C4M (Ubiquinol oxidase) subunit I KBNAB1_1765 ENOG4105PV3 Inner membrane protein yqiJ KBNAB1_1768 ENOG4105E0K tonB-dependent siderophore receptor KBNAB1_1770 ENOG4105HDD phospholipase KBNAB1_1771 ENOG4105CZN Potassium uptake protein KBNAB1_1773 ENOG4105C7B Threonine dehydratase KBNAB1_1779 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) KBNAB1_1780 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit KBNAB1_1782 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) KBNAB1_1785 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase KBNAB1_1794 ENOG4107VMU Membrane KBNAB1_1795 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) KBNAB1_1797 ENOG4107QP7 CoA-transferase subunit A KBNAB1_1798 ENOG4107QNJ CoA-transferase subunit B KBNAB1_1799 ENOG4105CHU acetyl-coa acetyltransferase KBNAB1_1800 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase KBNAB1_1801 ENOG4105F2Z 3-oxoadipate enol-lactonase KBNAB1_1802 ENOG4105D2S major facilitator superfamily KBNAB1_1803 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase KBNAB1_1804 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta KBNAB1_1805 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha KBNAB1_1806 ENOG4105FF2 Type I DHQase KBNAB1_1807 ENOG4106JPM 3-dehydroshikimate dehydratase KBNAB1_1808 ENOG4105TW1 Carbohydrate-selective porin OprB KBNAB1_1809 ENOG4105DZG Dehydrogenase KBNAB1_1811 ENOG4105MD1 YeeE YedE family protein KBNAB1_1814 ENOG4107HP6 Transcriptional regulator KBNAB1_1815 ENOG4108PTX LysR family Transcriptional regulator KBNAB1_1816 ENOG4105C1G acyl-Coa dehydrogenase KBNAB1_1821 ENOG4105DNH Major Facilitator KBNAB1_1823 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) KBNAB1_1827 ENOG4105FUY alpha subunit KBNAB1_1829 ENOG4105CHR reductase KBNAB1_1833 ENOG4105F11 amine oxidase KBNAB1_1835 ENOG4105C26 Dehydrogenase KBNAB1_1837 ENOG4105F2Z 3-oxoadipate enol-lactonase KBNAB1_1838 ENOG4105CHU acetyl-coa acetyltransferase KBNAB1_1839 ENOG4107QNJ CoA-transferase subunit B KBNAB1_1840 ENOG4107QP7 CoA-transferase subunit A KBNAB1_1842 ENOG4105NN7 muconolactone delta-isomerase KBNAB1_1843 ENOG4105DTQ mandelate racemase muconate lactonizing KBNAB1_1844 ENOG4108KB2 LysR family Transcriptional regulator KBNAB1_1846 ENOG4107EJG GntR family transcriptional regulator KBNAB1_1850 ENOG4105CZJ Aldehyde dehydrogenase KBNAB1_1854 ENOG4105C1G acyl-Coa dehydrogenase KBNAB1_1855 ENOG4105CHR reductase KBNAB1_1856 ENOG4108JU7 Transcriptional regulator KBNAB1_1858 ENOG41062QD Membrane KBNAB1_1861 ENOG4107RGH Aldehyde dehydrogenase KBNAB1_1864 ENOG4105CH6 catalase KBNAB1_1869 ENOG4105K56 Transcriptional regulator KBNAB1_1870 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase KBNAB1_1872 ENOG4105NAE bifunctional deaminase-reductase domain protein KBNAB1_1878 ENOG4107Z3H Transcriptional regulator, TetR family KBNAB1_1880 ENOG4105CHJ isochorismatase hydrolase KBNAB1_1881 ENOG4105EJC lysr family transcriptional regulator KBNAB1_1882 ENOG4105D8V Glucose sorbosone dehydrogenase KBNAB1_1883 ENOG4105CKD glutathione-regulated potassium-efflux system protein KBNAB1_1885 ENOG4105CH2 amidohydrolase KBNAB1_1889 ENOG4105D5K Hemolysin activator protein KBNAB1_1890 ENOG4105CKT filamentous hemagglutinin KBNAB1_1896 ENOG4105FDP GntR family transcriptional regulator KBNAB1_1899 ENOG4106KR7 LysR family Transcriptional regulator KBNAB1_1904 ENOG4108JQ1 Dehydrogenase KBNAB1_1905 ENOG4105JSC dimethylmenaquinone methyltransferase KBNAB1_1911 ENOG4105CW7 secretion protein, HlyD family KBNAB1_1914 ENOG4105CZJ Aldehyde dehydrogenase KBNAB1_1915 ENOG4105C01 Dihydroxy-acid dehydratase KBNAB1_1917 ENOG4105DDW LysR family Transcriptional regulator KBNAB1_1918 ENOG4105EXW epimerase dehydratase KBNAB1_1920 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase KBNAB1_1921 ENOG4105CF7 AraC family transcriptional regulator KBNAB1_1924 ENOG4105DQ4 alcohol dehydrogenase KBNAB1_1926 ENOG4105EHG Permease protein KBNAB1_1927 ENOG4105E0A ABC, transporter KBNAB1_1931 ENOG4105C5T Phosphoribosyl pyrophosphate synthase KBNAB1_1948 ENOG4108UAJ Transcriptional regulator KBNAB1_1957 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) KBNAB1_1968 ENOG4108BAS reductase KBNAB1_1971 ENOG4108R6W Transcriptional regulator, ARAC family KBNAB1_1972 ENOG4108821 RND type efflux pump KBNAB1_1973 ENOG4105E0F Histidine kinase KBNAB1_1974 ENOG4105CK6 Two component transcriptional regulator (Winged helix family KBNAB1_1975 ENOG4105C1P efflux transporter, rnd family, mfp subunit KBNAB1_1976 ENOG4105BZS acriflavin resistance protein KBNAB1_1977 ENOG4105ENJ RND efflux system, outer membrane lipoprotein KBNAB1_1979 ENOG4105CT3 Monooxygenase KBNAB1_1983 ENOG4105CJP fad dependent oxidoreductase KBNAB1_1987 ENOG4105X0I Fimbrial KBNAB1_1999 ENOG4107RZC phospholipase d KBNAB1_2003 ENOG4108IGT Dipeptidase KBNAB1_2009 ENOG4107T31 5'-nucleotidase KBNAB1_2011 ENOG4105WQI isochorismatase KBNAB1_2012 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase KBNAB1_2014 ENOG4105E0C molybdate abc transporter KBNAB1_2015 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein KBNAB1_2016 ENOG4105F4R Transcriptional regulator mode KBNAB1_2017 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit KBNAB1_2018 ENOG4108YS2 small subunit KBNAB1_2019 ENOG4105F57 Anthranilate dioxygenase reductase KBNAB1_2025 ENOG4105CHR reductase KBNAB1_2027 ENOG4105D2S major facilitator superfamily KBNAB1_2028 ENOG4105CF7 AraC family transcriptional regulator KBNAB1_2031 ENOG4105DTD Dehydrogenase KBNAB1_2032 ENOG4105CY2 Citrate transporter KBNAB1_2034 ENOG4108M0I Transcriptional regulator KBNAB1_2036 ENOG4107QNJ CoA-transferase subunit B KBNAB1_2037 ENOG4105CRW Short chain fatty acid transporter KBNAB1_2038 ENOG4105CHU acetyl-coa acetyltransferase KBNAB1_2040 ENOG4107YNJ LysR family Transcriptional regulator KBNAB1_2043 ENOG4108IJ0 Aspartate ammonia-lyase KBNAB1_2045 ENOG4105CSH Transporter KBNAB1_2049 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component KBNAB1_2050 ENOG4106FTQ Taurine ABC transporter, periplasmic KBNAB1_2053 ENOG4105FDP GntR family transcriptional regulator KBNAB1_2055 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) KBNAB1_2056 ENOG4105KVH Transcriptional regulator KBNAB1_2057 ENOG4105UEI Transcriptional Regulator AraC Family KBNAB1_2060 ENOG4108VCT Sulfite exporter TauE/SafE KBNAB1_2062 ENOG4107QPB Beta-lactamase domain protein KBNAB1_2064 ENOG4105FFC UPF0187 protein KBNAB1_2066 ENOG4105CHR reductase KBNAB1_2069 ENOG4105CPP Dehydrogenase, E1 component KBNAB1_2070 ENOG4107R0V Pyruvate dehydrogenase KBNAB1_2071 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) KBNAB1_2074 ENOG4105BZU Histidine kinase KBNAB1_2076 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) KBNAB1_2077 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) KBNAB1_2086 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) KBNAB1_2089 ENOG4105C28 cystathionine KBNAB1_2091 ENOG4105F2W methyltransferase KBNAB1_2097 ENOG4105K59 histidine triad (HIT) protein KBNAB1_2102 ENOG4107QWP ABC-2 type transporter KBNAB1_2103 ENOG4107QWP ABC-2 type transporter KBNAB1_2104 ENOG4105CJ1 ABC, transporter KBNAB1_2107 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) KBNAB1_2108 ENOG4105CNM Receptor KBNAB1_2112 ENOG4107TSN permease KBNAB1_2113 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) KBNAB1_2117 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) KBNAB1_2118 ENOG4108YZT Adenosylcobinamide kinase KBNAB1_2120 ENOG4107VXZ Hydrolase KBNAB1_2128 ENOG4105DJU Siderophore biosynthesis protein KBNAB1_2129 ENOG4105DUU IucA IucC family protein KBNAB1_2133 ENOG4108Z66 YbaK ebsC protein KBNAB1_2136 ENOG4105C1G acyl-Coa dehydrogenase KBNAB1_2137 ENOG4105C1G acyl-Coa dehydrogenase KBNAB1_2138 ENOG4105EEF Alkane 1-monooxygenase KBNAB1_2139 ENOG4105E7U AraC family transcriptional regulator KBNAB1_2140 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) KBNAB1_2141 ENOG4105K70 DNA-binding protein KBNAB1_2144 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family KBNAB1_2146 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins KBNAB1_2147 ENOG4108Z4V iron-sulfur cluster assembly KBNAB1_2150 ENOG4108ZIT Ferredoxin, 2FE-2S KBNAB1_2151 ENOG4105F8J Adenylate Guanylate cyclase KBNAB1_2153 ENOG4108JA2 transcriptioN-repair coupling factor KBNAB1_2157 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) KBNAB1_2158 ENOG4105K4T epimerase KBNAB1_2161 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase KBNAB1_2165 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component KBNAB1_2167 ENOG4105DGW oligopeptidase A KBNAB1_2175 ENOG4105SG9 biopolymer transport protein, ExbD KBNAB1_2177 ENOG4107QP3 malate synthase g KBNAB1_2178 ENOG4105D6Z AFG1 family ATPase KBNAB1_2180 ENOG4107RN6 Monooxygenase KBNAB1_2184 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) KBNAB1_2185 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) KBNAB1_2188 ENOG4108Z6B deaminase KBNAB1_2192 ENOG4108RTD type II secretion system protein K KBNAB1_2197 ENOG4105F8V Hydrolase, tatD family KBNAB1_2199 ENOG4107QRG dna polymerase iii KBNAB1_2201 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) KBNAB1_2202 ENOG4105BZ1 (ABC) transporter KBNAB1_2205 ENOG4105FA0 parb-like partition protein KBNAB1_2206 ENOG4107QJE Chromosome Partitioning Protein KBNAB1_2208 ENOG4108S0S Nucleotidyl transferase KBNAB1_2209 ENOG4105EHM Aminoglycoside phosphotransferase KBNAB1_2210 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) KBNAB1_2211 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) KBNAB1_2212 ENOG4105D2N Aldolase KBNAB1_2216 ENOG4108UHJ MAF-like protein KBNAB1_2217 ENOG4105EZE Cupin 4 family protein KBNAB1_2219 ENOG41080HT Transcriptional regulator, arsr family KBNAB1_2221 ENOG4105XPP Protein of unknown function (DUF1275) KBNAB1_2222 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme KBNAB1_2223 ENOG4105BZ1 (ABC) transporter KBNAB1_2225 ENOG4108ZX5 transcriptional regulator KBNAB1_2227 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) KBNAB1_2228 ENOG4105CK7 Sodium proline symporter KBNAB1_2229 ENOG4105EW9 transcriptional regulator AsnC family KBNAB1_2230 ENOG4105C26 Dehydrogenase KBNAB1_2231 ENOG4105YGK Pfam:UPF0157 KBNAB1_2234 ENOG4108T58 Mg2 transport protein CorA KBNAB1_2236 ENOG4108YYC ycei family KBNAB1_2238 ENOG4105CV1 Transketolase (EC 2.2.1.1) KBNAB1_2243 ENOG4108HWY Beta-lactamase KBNAB1_2247 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) KBNAB1_2248 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) KBNAB1_2252 ENOG4105X0I Fimbrial KBNAB1_2253 ENOG4105GQR Chaperone KBNAB1_2258 ENOG4108IPJ Membrane KBNAB1_2260 ENOG4105ETS cytosine purines uracil thiamine allantoin KBNAB1_2262 ENOG4105CC0 LysR family Transcriptional regulator KBNAB1_2266 ENOG41067SE Tetr family transcriptional regulator KBNAB1_2271 ENOG4105EW9 transcriptional regulator AsnC family KBNAB1_2273 ENOG4105CDA abc transporter atp-binding protein KBNAB1_2274 ENOG4105DRP amino acid AbC transporter KBNAB1_2275 ENOG4105EAD ABC transporter KBNAB1_2278 ENOG4107T8P acyl-Coa dehydrogenase KBNAB1_2281 ENOG4105D01 (LipO)protein KBNAB1_2282 ENOG4105D01 (LipO)protein KBNAB1_2283 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) KBNAB1_2284 ENOG4108UMI ABC transporter, permease KBNAB1_2285 ENOG4105C3G gtp-binding protein KBNAB1_2290 ENOG4108UMN azlc family KBNAB1_2291 ENOG4105ZED uncharacterized protein ygaH KBNAB1_2297 ENOG4105E7U AraC family transcriptional regulator KBNAB1_2302 ENOG4105CHM Aminotransferase KBNAB1_2305 ENOG4105C0B DNA polymerase III (alpha subunit) KBNAB1_2310 ENOG4108JU3 Alkyl hydroperoxide reductase KBNAB1_2313 ENOG4108KB2 LysR family Transcriptional regulator KBNAB1_2314 ENOG4105D6J arsenicaL-resistance protein KBNAB1_2315 ENOG41082YX Transcriptional regulator, arsr family KBNAB1_2318 ENOG4105CPN adenine deaminase KBNAB1_2320 ENOG4105CBN LysR family transcriptional regulator KBNAB1_2322 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease KBNAB1_2324 ENOG4105E2B Taurine dioxygenase KBNAB1_2325 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component KBNAB1_2326 ENOG4108IY8 ABC, transporter KBNAB1_2327 ENOG4106FTQ Taurine ABC transporter, periplasmic KBNAB1_2330 ENOG4105C54 Major Facilitator superfamily KBNAB1_2334 ENOG4105C4M (Ubiquinol oxidase) subunit I KBNAB1_2335 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii KBNAB1_2337 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family KBNAB1_2338 ENOG4108K70 Transcriptional regulator KBNAB1_2341 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase KBNAB1_2342 ENOG4105PSI phosphoribosyl-dephospho-CoA transferase KBNAB1_2345 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) KBNAB1_2346 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase KBNAB1_2348 ENOG4105DXI Major Facilitator superfamily KBNAB1_2352 ENOG41067MG lrgb family KBNAB1_2353 ENOG4105VAW lrga family KBNAB1_2354 ENOG4105CMU LysR family (Transcriptional regulator KBNAB1_2355 ENOG4108SHQ Glutathione S-transferase KBNAB1_2356 ENOG4105CYM Glutathione S-transferase KBNAB1_2357 ENOG4105CBN LysR family transcriptional regulator KBNAB1_2358 ENOG4105CHR reductase KBNAB1_2360 ENOG4105D7W serine acetyltransferase KBNAB1_2361 ENOG4105ESN nucleotide-binding protein KBNAB1_2362 ENOG4105C9B Cysteine desulfurase KBNAB1_2364 ENOG4105EXG Transcriptional regulator KBNAB1_2365 ENOG4105CT1 (ABC) transporter KBNAB1_2366 ENOG4107RP9 extracellular solute-binding protein, family 3 KBNAB1_2367 ENOG4105CDA abc transporter atp-binding protein KBNAB1_2368 ENOG4108HW4 amino acid AbC transporter KBNAB1_2369 ENOG4105EAD ABC transporter KBNAB1_2371 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase KBNAB1_2372 ENOG4105BZU Histidine kinase KBNAB1_2374 ENOG4105EW9 transcriptional regulator AsnC family KBNAB1_2376 ENOG4105KT5 UmuD protein KBNAB1_2380 ENOG4105CYX Short-chain dehydrogenase reductase Sdr KBNAB1_2391 ENOG4105HEI LysR family (Transcriptional regulator KBNAB1_2395 ENOG4105CEY Amp-dependent synthetase and ligase KBNAB1_2396 ENOG4105R8C Transcriptional regulator KBNAB1_2397 ENOG4105C1G acyl-Coa dehydrogenase KBNAB1_2398 ENOG4107QX3 carboxylase KBNAB1_2399 ENOG4105E39 Enoyl-CoA hydratase KBNAB1_2402 ENOG4105CC0 LysR family Transcriptional regulator KBNAB1_2405 ENOG4105CSU acyl-Coa dehydrogenase KBNAB1_2407 ENOG4105EQ0 Major Facilitator superfamily KBNAB1_2409 ENOG4107QNJ CoA-transferase subunit B KBNAB1_2410 ENOG4107QP7 CoA-transferase subunit A KBNAB1_2411 ENOG4107RGD Major Facilitator superfamily KBNAB1_2412 ENOG4105C1G acyl-Coa dehydrogenase KBNAB1_2413 ENOG4105E39 Enoyl-CoA hydratase KBNAB1_2414 ENOG4105CHR reductase KBNAB1_2415 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase KBNAB1_2416 ENOG4105CHU acetyl-coa acetyltransferase KBNAB1_2418 ENOG4105EQ0 Major Facilitator superfamily KBNAB1_2419 ENOG4105EA8 2-Nitropropane dioxygenase KBNAB1_2420 ENOG4108UKI Enoyl-CoA hydratase KBNAB1_2423 ENOG4105C1G acyl-Coa dehydrogenase KBNAB1_2424 ENOG4107RGD Major Facilitator superfamily KBNAB1_2425 ENOG4108KAZ Involved in phosphonate degradation (By similarity) KBNAB1_2426 ENOG4107STF Involved in phosphonate degradation (By similarity) KBNAB1_2428 ENOG4107RCV ABC transporter, permease KBNAB1_2429 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) KBNAB1_2430 ENOG4105C4Y ABC transporter KBNAB1_2432 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase KBNAB1_2433 ENOG4107HP6 Transcriptional regulator KBNAB1_2435 ENOG4105HEI LysR family (Transcriptional regulator KBNAB1_2436 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase KBNAB1_2437 ENOG4105C26 Dehydrogenase KBNAB1_2439 ENOG4105ETS cytosine purines uracil thiamine allantoin KBNAB1_2440 ENOG4105C26 Dehydrogenase KBNAB1_2441 ENOG4108M8W Monooxygenase KBNAB1_2442 ENOG4105MXW flavin reductase domain protein, FMN-binding KBNAB1_2443 ENOG4108MXF Alpha Beta Hydrolase KBNAB1_2447 ENOG4105CPW cytochrome b561 KBNAB1_2448 ENOG4107VGR Catalase KBNAB1_2456 ENOG4107YAU phenylacetic acid degradation protein KBNAB1_2458 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein KBNAB1_2459 ENOG4105DZS Phenylacetate-CoA ligase KBNAB1_2460 ENOG4105CHU acetyl-coa acetyltransferase KBNAB1_2461 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase KBNAB1_2462 ENOG4108UKI Enoyl-CoA hydratase KBNAB1_2463 ENOG4105E39 Enoyl-CoA hydratase KBNAB1_2464 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) KBNAB1_2465 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit KBNAB1_2466 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit KBNAB1_2467 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit KBNAB1_2468 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit KBNAB1_2469 ENOG4105DXM phenylacetic acid degradation protein KBNAB1_2470 ENOG4105EJQ L-serine dehydratase KBNAB1_2471 ENOG4107QTZ amino acid KBNAB1_2472 ENOG4105CZJ Aldehyde dehydrogenase KBNAB1_2477 ENOG4105MWK D-amino acid dehydrogenase, small subunit KBNAB1_2481 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) KBNAB1_2484 ENOG4108Z4X TRANSCRIPTIONal KBNAB1_2490 ENOG4108HW3 (ABC) transporter KBNAB1_2492 ENOG4105MRR Transcriptional regulator (By similarity) KBNAB1_2495 ENOG4105KVH Transcriptional regulator KBNAB1_2496 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF KBNAB1_2497 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase KBNAB1_2500 ENOG4105E2A Dehydrogenase KBNAB1_2502 ENOG4105R8C Transcriptional regulator KBNAB1_2507 ENOG4107R4J Chloride channel KBNAB1_2508 ENOG4108JIK carboxylase KBNAB1_2512 ENOG4105C5A transporter KBNAB1_2513 ENOG4108WAV Transcriptional regulator KBNAB1_2516 ENOG4105CNA YD repeat protein KBNAB1_2522 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) KBNAB1_2526 ENOG4105D2S major facilitator superfamily KBNAB1_2528 ENOG4105D1S lipid A biosynthesis KBNAB1_2529 ENOG4105BZU Histidine kinase KBNAB1_2530 ENOG4107AQZ Membrane KBNAB1_2534 ENOG4108Z4U Ferredoxin KBNAB1_2542 ENOG4105DFG type I secretion outer membrane protein KBNAB1_2543 ENOG4108IUZ ABC transporter KBNAB1_2544 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA KBNAB1_2546 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase KBNAB1_2547 ENOG4105C2X Arabinose 5-phosphate isomerase KBNAB1_2553 ENOG4107YPT transcriptional regulator KBNAB1_2559 ENOG4105II7 pyrroline-5-carboxylate reductase KBNAB1_2561 ENOG4105VEQ Cold shock protein KBNAB1_2562 ENOG410829K Lysine exporter protein (Lyse ygga) KBNAB1_2568 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) KBNAB1_2578 ENOG4108KB2 LysR family Transcriptional regulator KBNAB1_2579 ENOG4105FUY alpha subunit KBNAB1_2580 ENOG4108UKV benzoate 1,2-dioxygenase KBNAB1_2581 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein KBNAB1_2582 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase KBNAB1_2583 ENOG4105DKK Benzoate KBNAB1_2584 ENOG4105D2S major facilitator superfamily KBNAB1_2587 ENOG4105CQ7 ATP-dependent helicase KBNAB1_2588 ENOG4105D3R alkyl hydroperoxide reductase KBNAB1_2590 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) KBNAB1_2592 ENOG4108JU3 Alkyl hydroperoxide reductase KBNAB1_2594 ENOG4108K3A Glutathione S-transferase KBNAB1_2596 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) KBNAB1_2597 ENOG4108TGY Glutathione S-transferase KBNAB1_2599 ENOG4108ZG0 Ompa motb domain protein KBNAB1_2600 ENOG4105CD3 dihydroorotase KBNAB1_2606 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit KBNAB1_2609 ENOG4108UKZ OsmC family KBNAB1_2610 ENOG4107RYR Transcriptional regulator, Crp Fnr family KBNAB1_2613 ENOG4105CPC Aldo Keto reductase KBNAB1_2616 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis KBNAB1_2618 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase KBNAB1_2620 ENOG4105CFH Aspartokinase KBNAB1_2622 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) KBNAB1_2624 ENOG4105CPW cytochrome b561 KBNAB1_2625 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) KBNAB1_2626 ENOG4105C7N Xanthine uracil vitamin C permease KBNAB1_2628 ENOG4105F95 Monooxygenase KBNAB1_2635 ENOG4105F95 Monooxygenase KBNAB1_2648 ENOG4108C33 Resolvase KBNAB1_2649 ENOG4105D13 transposase KBNAB1_2653 ENOG4105C85 amino acid KBNAB1_2657 ENOG4105C26 Dehydrogenase KBNAB1_2661 ENOG4105CUB amino acid KBNAB1_2663 ENOG4105C85 amino acid KBNAB1_2671 ENOG4105CNA YD repeat protein KBNAB1_2675 ENOG4105D01 (LipO)protein KBNAB1_2676 ENOG4108M3P Membrane KBNAB1_2678 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase KBNAB1_2682 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) KBNAB1_2685 ENOG4108JQ5 ABC transporter KBNAB1_2686 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component KBNAB1_2687 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component KBNAB1_2689 ENOG4105E9H Lytic Murein transglycosylase KBNAB1_2689 ENOG4105E9H Lytic Murein transglycosylase KBNAB1_2690 ENOG4107RZZ dna polymerase iii epsilon subunit KBNAB1_2692 ENOG4105E09 nadh pyrophosphatase KBNAB1_2694 ENOG4105W4M Transport-associated protein KBNAB1_2696 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) KBNAB1_2698 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) KBNAB1_2699 ENOG4108ZUB Lysine exporter protein (Lyse ygga) KBNAB1_2703 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family KBNAB1_2704 ENOG4105D0A hydroxylase KBNAB1_2705 ENOG4107RAQ aminopeptidase KBNAB1_2712 ENOG4105DIJ Phosphoethanolamine transferase KBNAB1_2721 ENOG4105DR5 peptidase KBNAB1_2785 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase KBNAB1_2792 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b KBNAB1_2794 ENOG4105D82 Glutamate dehydrogenase KBNAB1_2795 ENOG4108R3D Electron transport complex KBNAB1_2796 ENOG4105CSM endonuclease III KBNAB1_2800 ENOG4105CJN penicillin-binding protein KBNAB1_2801 ENOG4106H78 methyltransferase KBNAB1_2804 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) KBNAB1_2806 ENOG4105CQM Urea amidohydrolase subunit alpha KBNAB1_2812 ENOG4107RET Isocitrate lyase KBNAB1_2814 ENOG4105C37 (CBS) domain KBNAB1_2815 ENOG4105D4T Citrate transporter KBNAB1_2818 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) KBNAB1_2821 ENOG4108MRJ KBNAB1_2825 ENOG4105VCQ rubredoxin KBNAB1_2826 ENOG4107QZF nitrite reductase NADPH large subunit KBNAB1_2828 ENOG4105C5Q Transcriptional regulator KBNAB1_2832 ENOG4107U91 Rhomboid family KBNAB1_2833 ENOG4105CV6 ABC transporter, permease KBNAB1_2834 ENOG4108I0Y (ABC) transporter KBNAB1_2835 ENOG4108UJV acyl-CoA thioesterase i KBNAB1_2839 ENOG4107RNH Outer membrane receptor FepA KBNAB1_2842 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) KBNAB1_2843 ENOG4105E6M Sulphatase-modifying factor protein KBNAB1_2847 ENOG4105CJ3 phosphate transporter KBNAB1_2848 ENOG4105C3R Methionine synthase KBNAB1_2851 ENOG4105CSP Major Facilitator Superfamily KBNAB1_2853 ENOG4108PZW LysR family Transcriptional regulator KBNAB1_2855 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) KBNAB1_2856 ENOG4105EU0 Major facilitator Superfamily KBNAB1_2857 ENOG4108R6W Transcriptional regulator, ARAC family KBNAB1_2858 ENOG4105CSV Glutaminase KBNAB1_2859 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) KBNAB1_2861 ENOG4105CSH Transporter KBNAB1_2863 ENOG4105C7K acetolactate synthase KBNAB1_2866 ENOG4105CHR reductase KBNAB1_2867 ENOG4108MXF Alpha Beta Hydrolase KBNAB1_2869 ENOG4105DJB Major Facilitator Superfamily KBNAB1_2870 ENOG4108DNI pyridine nucleotide-disulfide oxidoreductase KBNAB1_2872 ENOG4105CHR reductase KBNAB1_2876 ENOG41069M3 Transcriptional regulator KBNAB1_2879 ENOG4106YT9 Enoyl-CoA hydratase KBNAB1_2881 ENOG4105CND Glycosyl transferase, family 2 KBNAB1_2882 ENOG4107BJW polysaccharide deacetylase KBNAB1_2884 ENOG4108VWS Yaeq family KBNAB1_2886 ENOG4105CKI cobalamin synthesis protein KBNAB1_2890 ENOG4105C94 Transporter KBNAB1_2891 ENOG4105C94 Transporter KBNAB1_2892 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) KBNAB1_2897 ENOG4107QK5 Homocysteine s-methyltransferase KBNAB1_2898 ENOG4105D5Q Arginine ornithine antiporter KBNAB1_2903 ENOG4108YNN Heme oxygenase KBNAB1_2909 ENOG4108SF5 RNA Polymerase KBNAB1_2911 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) KBNAB1_2912 ENOG4105C54 Major Facilitator superfamily KBNAB1_2923 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) KBNAB1_2939 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) KBNAB1_2948 ENOG4105K4U addiction module toxin, RelE StbE family KBNAB1_2977 ENOG4105VTN Protein of unknown function (DUF1311) KBNAB1_3009 ENOG41083X2 DNA polymerase III, epsilon subunit KBNAB1_3014 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) KBNAB1_3015 ENOG4105C0R drug resistance transporter emrb qaca subfamily KBNAB1_3016 ENOG4105CW7 secretion protein, HlyD family KBNAB1_3017 ENOG4108VUY thioesterase Superfamily protein KBNAB1_3018 ENOG4105D52 delta-aminolevulinic acid dehydratase KBNAB1_3019 ENOG4105MWK D-amino acid dehydrogenase, small subunit KBNAB1_3020 ENOG4105ECP epimerase KBNAB1_3024 ENOG4107RH8 nuclease SbcCD subunit D KBNAB1_3025 ENOG4105EYH Exonuclease KBNAB1_3026 ENOG4105DFA alanine racemase domain protein KBNAB1_3027 ENOG4105CZX twitching motility protein KBNAB1_3028 ENOG4105CZX twitching motility protein KBNAB1_3029 ENOG41090R7 Ferric uptake KBNAB1_3034 ENOG4105E7A Glutamine amidotransferase KBNAB1_3037 ENOG4107QKV phosphomannomutase KBNAB1_3039 ENOG4105C4R Atp-dependent dna helicase KBNAB1_3041 ENOG4108ZG0 Ompa motb domain protein KBNAB1_3042 ENOG4106HNH Acyl-transferase KBNAB1_3045 ENOG4107QMS site-determining protein KBNAB1_3051 ENOG4105CNU cell division protein FtsK KBNAB1_3052 ENOG4105C3M thioredoxin reductase KBNAB1_3053 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) KBNAB1_3055 ENOG4105KEG ribosomal-protein-alanine acetyltransferase KBNAB1_3064 ENOG4108YXA Membrane KBNAB1_3065 ENOG4105EUB pirin domain protein KBNAB1_3067 ENOG4105C4K Nad synthetase KBNAB1_3069 ENOG4105E3J oxidoreductase KBNAB1_3070 ENOG4105C26 Dehydrogenase KBNAB1_3071 ENOG4105DVW rieske (2Fe-2S) KBNAB1_3073 ENOG4105C94 Transporter KBNAB1_3074 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) KBNAB1_3075 ENOG4105EJC lysr family transcriptional regulator KBNAB1_3077 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding KBNAB1_3081 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase KBNAB1_3082 ENOG4105C34 Pseudouridine synthase KBNAB1_3083 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane KBNAB1_3084 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) KBNAB1_3087 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) KBNAB1_3089 ENOG4105C5T Phosphoribosyl pyrophosphate synthase KBNAB1_3095 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) KBNAB1_3097 ENOG4105DWF phosphomethylpyrimidine kinase KBNAB1_3098 ENOG4109066 lysm domain bon superfamily protein KBNAB1_3100 ENOG4105CHR reductase KBNAB1_3101 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase KBNAB1_3103 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein KBNAB1_3104 ENOG4108BPE -transporting atpase KBNAB1_3105 ENOG4107RTD sua5 ycio yrdc ywlc family protein KBNAB1_3106 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) KBNAB1_3107 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) KBNAB1_3108 ENOG4105FE9 pseudouridine synthase KBNAB1_3110 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) KBNAB1_3111 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) KBNAB1_3113 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) KBNAB1_3114 ENOG4108K4C ec 3.1.3.12 KBNAB1_3115 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase KBNAB1_3116 ENOG4106UW1 Major Facilitator superfamily KBNAB1_3120 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) KBNAB1_3122 ENOG4105HF0 Membrane KBNAB1_3125 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY KBNAB1_3127 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) KBNAB1_3137 ENOG4105D1F ATP-binding protein KBNAB1_3139 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) KBNAB1_3145 ENOG4105K6H D-cysteine desulfhydrase KBNAB1_3146 ENOG4105CBX hi0933 family KBNAB1_3151 ENOG4105DP0 ferredoxin-NADP reductase KBNAB1_3152 ENOG4105DUM transcriptional regulator, lysR family KBNAB1_3156 ENOG4105C8S subunit m KBNAB1_3157 ENOG4105D65 subunit l KBNAB1_3159 ENOG4107UFS subunit j KBNAB1_3162 ENOG4108IEH NADH dehydrogenase subunit g KBNAB1_3163 ENOG4107QIZ NADH dehydrogenase KBNAB1_3164 ENOG4105GKE subunit e KBNAB1_3168 ENOG4105BZU Histidine kinase KBNAB1_3170 ENOG4105E0F Histidine kinase KBNAB1_3171 ENOG4107EXC regulatoR KBNAB1_3172 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) KBNAB1_3174 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) KBNAB1_3175 ENOG4105EB3 Histidine kinase KBNAB1_3189 ENOG4105DZG Dehydrogenase KBNAB1_3193 ENOG4105JAB phenazine biosynthesis protein, phzf family KBNAB1_3200 ENOG4105F6A helicase KBNAB1_3202 ENOG4105ECI YeeC-like protein KBNAB1_3203 ENOG4107QJE Chromosome Partitioning Protein KBNAB1_3206 ENOG4108HWY Beta-lactamase KBNAB1_3209 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) KBNAB1_3210 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) KBNAB1_3212 ENOG4105ETT transcriptional Regulator, LysR family KBNAB1_3216 ENOG4105CH2 amidohydrolase KBNAB1_3218 ENOG4106P55 Transcriptional regulator KBNAB1_3221 ENOG4106P55 Transcriptional regulator KBNAB1_3222 ENOG4107EFR Flavocytochrome c KBNAB1_3224 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F KBNAB1_3225 ENOG4107RGD Major Facilitator superfamily KBNAB1_3226 ENOG4105C1G acyl-Coa dehydrogenase KBNAB1_3227 ENOG4105ETT transcriptional Regulator, LysR family KBNAB1_3230 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) KBNAB1_3231 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) KBNAB1_3232 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) KBNAB1_3235 ENOG4105VR0 copper resistance KBNAB1_3236 ENOG4105E3B Multicopper oxidase KBNAB1_3238 ENOG4108HCJ Hydrolase KBNAB1_3239 ENOG4105DJV ribulose-phosphate 3-epimerase KBNAB1_3244 ENOG41072GX Peptidase M22 Glycoprotease KBNAB1_3245 ENOG4108Z0R Transferase KBNAB1_3256 ENOG4105CRQ synthase (Component I) KBNAB1_3258 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) KBNAB1_3259 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) KBNAB1_3260 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) KBNAB1_3269 ENOG4105K56 Transcriptional regulator KBNAB1_3270 ENOG4108ZHJ Organic hydroperoxide resistance protein KBNAB1_3271 ENOG4107QHF type ii secretion system protein e KBNAB1_3275 ENOG4105C2M dna polymerase I KBNAB1_3276 ENOG4108VIA integral membrane protein KBNAB1_3277 ENOG4105II7 pyrroline-5-carboxylate reductase KBNAB1_3278 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) KBNAB1_3280 ENOG4105C9X ppx gppa phosphatase KBNAB1_3282 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) KBNAB1_3285 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) KBNAB1_3290 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) KBNAB1_3293 ENOG4105W39 Membrane KBNAB1_3294 ENOG4105CYM Glutathione S-transferase KBNAB1_3297 ENOG4105CEY Amp-dependent synthetase and ligase KBNAB1_3298 ENOG4105N42 UPF0307 protein KBNAB1_3299 ENOG41080Z8 PHOSPHOCARRIER protein KBNAB1_3303 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase KBNAB1_3304 ENOG4105DJ0 Poly(A) Polymerase KBNAB1_3305 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein KBNAB1_3306 ENOG4105DXN mazG family KBNAB1_3308 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) KBNAB1_3311 ENOG4105C6T cysteine synthase KBNAB1_3312 ENOG4105BZU Histidine kinase KBNAB1_3313 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase KBNAB1_3314 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase KBNAB1_3315 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) KBNAB1_3318 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) KBNAB1_3319 ENOG4105W8H transhydrogenase (subunit alpha KBNAB1_3320 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) KBNAB1_3321 ENOG4106UX7 integral membrane protein KBNAB1_3324 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) KBNAB1_3326 ENOG4107RSM transcriptional regulator KBNAB1_3327 ENOG4105CUZ uba thif-type nad fad binding protein KBNAB1_3329 ENOG4107QM5 aconitate hydratase KBNAB1_3330 ENOG4105F8V Hydrolase, tatD family KBNAB1_3333 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) KBNAB1_3337 ENOG4105BZU Histidine kinase KBNAB1_3339 ENOG4108ZP8 Acetolactate synthase small subunit KBNAB1_3340 ENOG4105C7K acetolactate synthase KBNAB1_3345 ENOG4105DJY efflux transporter, rnd family, mfp subunit KBNAB1_3346 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) KBNAB1_3347 ENOG4105ENJ RND efflux system, outer membrane lipoprotein KBNAB1_3348 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH KBNAB1_3350 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) KBNAB1_3351 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) KBNAB1_3353 ENOG4105VW4 glutaredoxin 3 KBNAB1_3357 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) KBNAB1_3358 ENOG4105C2D reductase KBNAB1_3360 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) KBNAB1_3366 ENOG4105C84 Histidine ammonia-lyase KBNAB1_3369 ENOG4105CEY Amp-dependent synthetase and ligase KBNAB1_3372 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) KBNAB1_3376 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) KBNAB1_3380 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) KBNAB1_3384 ENOG4105WVQ Fe-S assembly protein IscX KBNAB1_3387 ENOG4105CN1 protease KBNAB1_3390 ENOG4106HB6 Alpha beta hydrolase KBNAB1_3392 ENOG4105C26 Dehydrogenase KBNAB1_3393 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family KBNAB1_3394 ENOG4105C6Z Gluconate KBNAB1_3395 ENOG4108UHU Aldolase KBNAB1_3396 ENOG4105C01 Dihydroxy-acid dehydratase KBNAB1_3397 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) KBNAB1_3398 ENOG4108DNC Involved in acetate metabolism (By similarity) KBNAB1_3399 ENOG4107GFK fumarate KBNAB1_3403 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) KBNAB1_3405 ENOG4108ESX Receptor KBNAB1_3407 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) KBNAB1_3409 ENOG4105DWV Homoserine O-trans-acetylase KBNAB1_3429 ENOG4105CIY formyltetrahydrofolate deformylase KBNAB1_3431 ENOG4107RGH Aldehyde dehydrogenase KBNAB1_3432 ENOG4105KDC 50s ribosomal protein l28 KBNAB1_3433 ENOG4105W0E 50S ribosomal protein L33 KBNAB1_3434 ENOG4105CKD glutathione-regulated potassium-efflux system protein KBNAB1_3438 ENOG4105VFU Rna-binding protein KBNAB1_3439 ENOG4105C4R Atp-dependent dna helicase KBNAB1_3443 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) KBNAB1_3445 ENOG4105KVH Transcriptional regulator KBNAB1_3447 ENOG41069P5 Protein slyX homolog KBNAB1_3448 ENOG4105C5H ABC transporter KBNAB1_3449 ENOG4105N14 lysine exporter protein LysE YggA KBNAB1_3450 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase KBNAB1_3452 ENOG4105CK2 sodium dicarboxylate symporter KBNAB1_3463 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) KBNAB1_3468 ENOG4105DUM transcriptional regulator, lysR family KBNAB1_3473 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase KBNAB1_3476 ENOG4108W5M transcriptional regulator KBNAB1_3479 ENOG4105D29 Helix-turn-helix type 11 domain protein KBNAB1_3480 ENOG4107XGZ Hydrolase KBNAB1_3481 ENOG4105EI2 Pseudouridine synthase KBNAB1_3482 ENOG4105C03 ribonuclease KBNAB1_3484 ENOG4105CBN LysR family transcriptional regulator KBNAB1_3485 ENOG4105EMU Dehydrogenase KBNAB1_3486 ENOG4105CSA Coproporphyrinogen iii oxidase KBNAB1_3488 ENOG4107QI1 Mate efflux family protein KBNAB1_3490 ENOG4107T8P acyl-Coa dehydrogenase KBNAB1_3498 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) KBNAB1_3499 ENOG4105C5X domain protein KBNAB1_3502 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) KBNAB1_3504 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase KBNAB1_3505 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) KBNAB1_3507 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) KBNAB1_3508 ENOG4108Z7R Chaperone CsaA KBNAB1_3510 ENOG4108VAU general secretion pathway protein G KBNAB1_3511 ENOG4105D7Q type ii secretion system KBNAB1_3512 ENOG4105C25 Primosomal protein n' KBNAB1_3513 ENOG4105CKD glutathione-regulated potassium-efflux system protein KBNAB1_3514 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) KBNAB1_3516 ENOG4105DVC DnaJ domain protein KBNAB1_3517 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) KBNAB1_3518 ENOG4107QUT magnesium and cobalt transport protein CorA KBNAB1_3522 ENOG4107QYX exodeoxyribonuclease v alpha KBNAB1_3523 ENOG4107QKA exodeoxyribonuclease V beta KBNAB1_3524 ENOG4105DSY exodeoxyribonuclease V, gamma KBNAB1_3526 ENOG4105CSR polyphosphate kinase 2 KBNAB1_3528 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) KBNAB1_3531 ENOG41061H0 Monooxygenase KBNAB1_3532 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase KBNAB1_3535 ENOG4105D65 subunit l KBNAB1_3536 ENOG4108ZE9 Monovalent cation H antiporter subunit C KBNAB1_3537 ENOG4107R4Z monovalent cation h antiporter subunit d KBNAB1_3538 ENOG4105SC1 monovalent cation H antiporter subunit E KBNAB1_3539 ENOG4105W4C monovalent cation H antiporter subunit F KBNAB1_3540 ENOG4105KJM monovalent cation h antiporter subunit g KBNAB1_3543 ENOG4105CHV Transcription elongation factor NusA KBNAB1_3545 ENOG4107EJC Preprotein translocase subunit SecG KBNAB1_3547 ENOG4107QHF type ii secretion system protein e KBNAB1_3550 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) KBNAB1_3552 ENOG4105C2N RNA methyltransferase TrmH family group 3 KBNAB1_3555 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) KBNAB1_3557 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) KBNAB1_3563 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) KBNAB1_3564 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase KBNAB1_3578 ENOG4107ZXU DSBA oxidoreductase KBNAB1_3581 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) KBNAB1_3584 ENOG4105D3Y Na H antiporter KBNAB1_3585 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) KBNAB1_3595 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) KBNAB1_3596 ENOG4105PM1 preprotein translocase subunit SecE KBNAB1_3600 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) KBNAB1_3601 ENOG4105TV9 FHA Domain-Containing protein KBNAB1_3602 ENOG4105GVR general secretion pathway protein D KBNAB1_3605 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS KBNAB1_3610 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) KBNAB1_3611 ENOG4108NEV two component transcriptional regulator, LytTR family KBNAB1_3612 ENOG4108HRK Histidine kinase KBNAB1_3615 ENOG4108UTW Plays a role in the regulation of phosphate uptake KBNAB1_3616 ENOG4105DFG type I secretion outer membrane protein KBNAB1_3617 ENOG4108RNG Permease of the drug metabolite transporter KBNAB1_3622 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) KBNAB1_3623 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters KBNAB1_3624 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) KBNAB1_3625 ENOG4105CNI cell division protein FtsW KBNAB1_3628 ENOG4105CE1 Ferrous iron transport protein b KBNAB1_3630 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) KBNAB1_3631 ENOG4105T95 Thiol disulfide interChange protein KBNAB1_3632 ENOG4105D6E homoserine dehydrogenase KBNAB1_3634 ENOG41061WM D-Alanyl-D-Alanine KBNAB1_3636 ENOG4107TUY Histidine kinase KBNAB1_3637 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family KBNAB1_3638 ENOG4105CN1 protease KBNAB1_3639 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) KBNAB1_3640 ENOG4108K5H permease YjgP YjgQ family protein KBNAB1_3648 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) KBNAB1_3650 ENOG4105BZU Histidine kinase KBNAB1_3653 ENOG4105C0P Mg chelatase subunit ChlI KBNAB1_3655 ENOG4105CHH sulfate transporter KBNAB1_3662 ENOG4105C0P Mg chelatase subunit ChlI KBNAB1_3663 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family KBNAB1_3665 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) KBNAB1_3668 ENOG4105EPF Outer membrane porin KBNAB1_3669 ENOG4105F0N pyrophosphate phospho-hydrolase KBNAB1_3672 ENOG4105CEY Amp-dependent synthetase and ligase KBNAB1_3673 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) KBNAB1_3674 ENOG41079KZ Major Facilitator Superfamily KBNAB1_3675 ENOG4105EN6 Membrane KBNAB1_3677 ENOG4105EE5 Membrane protein terC KBNAB1_3678 ENOG4108URH decarboxylase KBNAB1_3681 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) KBNAB1_3684 ENOG4105CCT upf0313 protein KBNAB1_3688 ENOG4105CS1 NAD(P)H quinone oxidoreductase KBNAB1_3690 ENOG4105C6T cysteine synthase KBNAB1_3692 ENOG4105Y7M Transcriptional regulator, TetR family KBNAB1_3699 ENOG4105C79 DNA protecting protein DprA KBNAB1_3702 ENOG4108IND Tetr family transcriptional regulator KBNAB1_3703 ENOG4107RTG Major Facilitator superfamily KBNAB1_3705 ENOG4108V06 Glutathione peroxidase KBNAB1_3713 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) KBNAB1_3718 ENOG4105FDK ABC transporter KBNAB1_3719 ENOG4105FAV ABC, transporter KBNAB1_3721 ENOG4105EZR dyp-type peroxidase family protein KBNAB1_3722 ENOG4107R1I NAD-dependent malic enzyme KBNAB1_3727 ENOG4105EUB pirin domain protein KBNAB1_3731 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) KBNAB1_3732 ENOG4106MP8 UPF0754 membrane protein KBNAB1_3733 ENOG4108VBZ doxx family KBNAB1_3734 ENOG4105DQR SNARE associated Golgi KBNAB1_3737 ENOG4107QJE Chromosome Partitioning Protein KBNAB1_3739 ENOG4107PSF BolA-like protein KBNAB1_3747 ENOG4105C1G acyl-Coa dehydrogenase KBNAB1_3753 ENOG4105CSH Transporter KBNAB1_3754 ENOG4105E39 Enoyl-CoA hydratase KBNAB1_3755 ENOG4105E39 Enoyl-CoA hydratase KBNAB1_3756 ENOG4105C1G acyl-Coa dehydrogenase KBNAB1_3758 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase KBNAB1_3759 ENOG4105C26 Dehydrogenase KBNAB1_3761 ENOG4105C85 amino acid KBNAB1_3762 ENOG4105C85 amino acid KBNAB1_3763 ENOG4105M4H endoribonuclease L-psp KBNAB1_3766 ENOG4105EW9 transcriptional regulator AsnC family KBNAB1_3771 ENOG4105D3G Pseudouridine synthase KBNAB1_3784 ENOG4108I0Z Aconitate hydratase KBNAB1_3785 ENOG4105BZN citrate synthase KBNAB1_3786 ENOG4105CR4 methylisocitrate lyase KBNAB1_3787 ENOG4105DRR Transcriptional regulator, GntR family KBNAB1_3788 ENOG4105CGF Aromatic amino acid aminotransferase KBNAB1_3789 ENOG4105CXG d-lactate dehydrogenase KBNAB1_3791 ENOG41073TP transcriptional regulator KBNAB1_3792 ENOG4105DAA L-lactate KBNAB1_3793 ENOG4107QKV phosphomannomutase KBNAB1_3794 ENOG4105CMR udp-glucose 4-epimerase KBNAB1_3796 ENOG4105C6Y Udp-glucose 6-dehydrogenase KBNAB1_3797 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase KBNAB1_3798 ENOG4105D3Q Sugar transferase KBNAB1_3799 ENOG4107UKG Glycosyl transferase, family 4 KBNAB1_3802 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase KBNAB1_3811 ENOG4107QQG Dehydrogenase KBNAB1_3812 ENOG4105DAY polysaccharide export protein KBNAB1_3814 ENOG4105D75 Capsular exopolysaccharide family KBNAB1_3815 ENOG4108V1T peptidylprolyl cis-trans isomerase KBNAB1_3816 ENOG4108V1T peptidylprolyl cis-trans isomerase KBNAB1_3817 ENOG4105CJR Integral membrane protein (MviN KBNAB1_3818 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase KBNAB1_3819 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase KBNAB1_3827 ENOG41062JF Transcriptional regulator KBNAB1_3830 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) KBNAB1_3831 ENOG4105UBK short-chain dehydrogenase reductase KBNAB1_3834 ENOG4107QZM n-acetylglutamate synthase KBNAB1_3835 ENOG4105GVF (ABC) transporter KBNAB1_3836 ENOG4105GVF (ABC) transporter KBNAB1_3837 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) KBNAB1_3838 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component KBNAB1_3839 ENOG4108VM9 ABC, transporter KBNAB1_3840 ENOG4108R86 Transcriptional regulator KBNAB1_3841 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) KBNAB1_3843 ENOG4105DTN riboflavin biosynthesis protein ribF KBNAB1_3844 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) KBNAB1_3846 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase KBNAB1_3849 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) KBNAB1_3860 ENOG4105CVE Lytic murein transglycosylase KBNAB1_3861 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit KBNAB1_3862 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) KBNAB1_3864 ENOG4105DFU Cell wall formation (By similarity) KBNAB1_3866 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase KBNAB1_3867 ENOG4105DU1 integral membrane protein, terc KBNAB1_3869 ENOG4106032 Glutathionylspermidine synthase KBNAB1_3871 ENOG4107QUY Guanine deaminase KBNAB1_3873 ENOG4108UGV hypoxanthine phosphoribosyltransferase KBNAB1_3875 ENOG4105T95 Thiol disulfide interChange protein KBNAB1_3876 ENOG4105PGM cation diffusion facilitator family transporter KBNAB1_3879 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins KBNAB1_3883 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS KBNAB1_3900 ENOG4105T95 Thiol disulfide interChange protein