locus-tag	class	description
J6B58_00005	COG0606	chelatase, subunit chli
J6B58_00015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J6B58_00025	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J6B58_00040	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J6B58_00055	COG0318	PFAM AMP-dependent synthetase and ligase
J6B58_00065	COG0477	Major facilitator Superfamily
J6B58_00070	COG2860	membrane
J6B58_00080	COG1253	flavin adenine dinucleotide binding
J6B58_00100	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J6B58_00135	COG0655	NAD(P)H dehydrogenase (quinone) activity
J6B58_00145	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J6B58_00215	COG0758	DNA mediated transformation
J6B58_00225	COG0697	spore germination
J6B58_00230	COG1309	transcriptional regulator
J6B58_00245	COG0386	Belongs to the glutathione peroxidase family
J6B58_00310	COG1121	(ABC) transporter
J6B58_00315	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J6B58_00320	COG1280	lysine exporter protein (LysE YggA)
J6B58_00325	COG2837	iron assimilation
J6B58_00330	COG0281	malic enzyme
J6B58_00375	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J6B58_00375	COG0519	Catalyzes the synthesis of GMP from XMP
J6B58_00380	COG4399	Belongs to the UPF0754 family
J6B58_00385	COG2259	Doxx family
J6B58_00390	COG0586	Pfam SNARE associated Golgi protein
J6B58_00405	COG1192	Involved in chromosome partitioning
J6B58_00415	COG0271	Belongs to the BolA IbaG family
J6B58_00435	COG2267	carboxylic ester hydrolase activity
J6B58_00455	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J6B58_00455	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J6B58_00455	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
J6B58_00455	COG3321	synthase
J6B58_00460	COG1960	acyl-CoA dehydrogenase activity
J6B58_00470	COG2197	response regulator
J6B58_00480	COG3916	Acyl-homoserine-lactone synthase
J6B58_00485	COG0477	Major facilitator Superfamily
J6B58_00490	COG1024	Enoyl-CoA hydratase
J6B58_00495	COG1024	Enoyl-CoA hydratase
J6B58_00500	COG1960	acyl-CoA dehydrogenase activity
J6B58_00505	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J6B58_00525	COG1113	amino acid transport
J6B58_00530	COG1113	amino acid transport
J6B58_00535	COG0251	oxidation-reduction process
J6B58_00575	COG0564	pseudouridine synthase activity
J6B58_00590	COG3328	transposase activity
J6B58_00620	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J6B58_00635	COG1802	Transcriptional regulator
J6B58_00645	COG1448	Aminotransferase
J6B58_00650	COG0277	FAD linked oxidase domain protein
J6B58_00660	COG2186	Transcriptional regulator
J6B58_00670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J6B58_00675	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J6B58_00690	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J6B58_00705	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J6B58_00720	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
J6B58_00755	COG1028	Short-chain dehydrogenase reductase Sdr
J6B58_00765	COG1028	Short-chain dehydrogenase reductase Sdr
J6B58_00770	COG1083	cytidylyl-transferase
J6B58_00775	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J6B58_00785	COG2089	acid synthase
J6B58_00790	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
J6B58_00795	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J6B58_00805	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
J6B58_00835	COG0728	peptidoglycan biosynthetic process
J6B58_00840	COG3023	N-Acetylmuramoyl-L-alanine amidase
J6B58_00900	COG0546	phosphoglycolate phosphatase activity
J6B58_00905	COG1028	Short-chain dehydrogenase reductase Sdr
J6B58_00925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J6B58_00930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J6B58_00935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J6B58_00940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J6B58_00945	COG1116	anion transmembrane transporter activity
J6B58_00950	COG1309	transcriptional regulator
J6B58_00955	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J6B58_00965	COG0196	riboflavin kinase activity
J6B58_00970	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J6B58_00980	COG1047	Peptidyl-prolyl cis-trans
J6B58_01020	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J6B58_01025	COG0657	acetylesterase activity
J6B58_01075	COG2951	lytic endotransglycosylase activity
J6B58_01080	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J6B58_01095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J6B58_01105	COG0671	phosphoesterase, PA-phosphatase related
J6B58_01110	COG0861	Integral membrane protein TerC family
J6B58_01120	COG0754	glutathionylspermidine amidase activity
J6B58_01130	COG0402	S-adenosylhomocysteine deaminase activity
J6B58_01145	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J6B58_01150	COG1230	cation diffusion facilitator family transporter
J6B58_01165	COG0706	membrane insertase activity
J6B58_01190	COG0592	DNA-directed DNA polymerase activity
J6B58_01200	COG0187	DNA topoisomerase II activity
J6B58_01210	COG0586	Pfam SNARE associated Golgi protein
J6B58_01215	COG0488	(ABC) transporter
J6B58_01240	COG0596	Alpha beta hydrolase
J6B58_01245	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
J6B58_01250	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J6B58_01290	COG0733	neurotransmitter:sodium symporter activity
J6B58_01300	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J6B58_01325	COG0583	DNA-binding transcription factor activity
J6B58_01330	COG2233	PERMEase
J6B58_01345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J6B58_01380	COG2814	Major facilitator Superfamily
J6B58_01385	COG0656	L-ascorbic acid biosynthetic process
J6B58_01390	COG0583	DNA-binding transcription factor activity
J6B58_01405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J6B58_01410	COG1064	alcohol dehydrogenase
J6B58_01415	COG2818	Glycosylase
J6B58_01430	COG1194	a g-specific adenine glycosylase
J6B58_01440	COG0400	carboxylic ester hydrolase activity
J6B58_01450	COG2983	Belongs to the UPF0260 family
J6B58_01455	COG2133	pyrroloquinoline quinone binding
J6B58_01460	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J6B58_01485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J6B58_01490	COG1335	isochorismatase
J6B58_01495	COG0385	Bile acid
J6B58_01500	COG0534	Mate efflux family protein
J6B58_01505	COG1683	Conserved Protein
J6B58_01525	COG0625	glutathione transferase activity
J6B58_01535	COG1113	amino acid transport
J6B58_01545	COG0523	cobalamin synthesis protein
J6B58_01555	COG2188	Transcriptional regulator
J6B58_01585	COG0010	Belongs to the arginase family
J6B58_01600	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J6B58_01605	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J6B58_01615	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J6B58_01620	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J6B58_01665	COG0753	catalase activity
J6B58_01725	COG0534	Mate efflux family protein
J6B58_01730	COG0436	Aminotransferase
J6B58_01735	COG2733	membrane
J6B58_01750	COG2918	glutathione biosynthetic process
J6B58_01775	COG2826	transposase and inactivated derivatives, IS30 family
J6B58_01800	COG1324	tolerance protein
J6B58_01805	COG0673	inositol 2-dehydrogenase activity
J6B58_01825	COG2826	transposase and inactivated derivatives, IS30 family
J6B58_01845	COG3150	esterase
J6B58_01855	COG1028	Short-chain dehydrogenase reductase Sdr
J6B58_01860	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
J6B58_01870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J6B58_01880	COG2233	PERMEase
J6B58_01885	COG2351	hydroxyisourate hydrolase activity
J6B58_01920	COG3706	GGDEF domain
J6B58_01935	COG1393	Belongs to the ArsC family
J6B58_01940	COG0708	Exodeoxyribonuclease III
J6B58_01960	COG0189	ligase activity
J6B58_01980	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J6B58_01990	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J6B58_02005	COG4942	peptidase
J6B58_02015	COG0508	dehydrogenase complex catalyzes the overall conversion of
J6B58_02025	COG2119	membrane
J6B58_02030	COG4774	siderophore transport
J6B58_02035	COG0426	domain, Protein
J6B58_02035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J6B58_02060	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J6B58_02080	COG1902	pentaerythritol trinitrate reductase activity
J6B58_02085	COG1519	Transferase
J6B58_02090	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J6B58_02095	COG0668	transmembrane transport
J6B58_02105	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J6B58_02110	COG1335	isochorismatase
J6B58_02115	COG1522	sequence-specific DNA binding
J6B58_02140	COG2205	protein histidine kinase activity
J6B58_02140	COG2198	Histidine kinase
J6B58_02140	COG0784	Response regulator, receiver
J6B58_02145	COG3162	membrane
J6B58_02150	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J6B58_02160	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J6B58_02180	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J6B58_02185	COG1309	transcriptional regulator
J6B58_02205	COG0351	phosphomethylpyrimidine kinase
J6B58_02205	COG0352	thiamine-phosphate diphosphorylase activity
J6B58_02205	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J6B58_02215	COG2814	Major facilitator Superfamily
J6B58_02230	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
J6B58_02240	COG1113	amino acid transport
J6B58_02250	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J6B58_02255	COG1012	belongs to the aldehyde dehydrogenase family
J6B58_02265	COG1335	isochorismatase
J6B58_02295	COG2814	Major facilitator Superfamily
J6B58_02300	COG0583	DNA-binding transcription factor activity
J6B58_02320	COG0667	Aldo Keto reductase
J6B58_02355	COG1733	regulation of RNA biosynthetic process
J6B58_02360	COG2249	NAD(P)H dehydrogenase (quinone) activity
J6B58_02430	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J6B58_02445	COG2329	Antibiotic biosynthesis monooxygenase
J6B58_02475	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J6B58_02505	COG0427	acetyl-CoA hydrolase
J6B58_02530	COG0659	secondary active sulfate transmembrane transporter activity
J6B58_02535	COG4221	oxidoreductase activity
J6B58_02540	COG2873	o-acetylhomoserine
J6B58_02545	COG0488	(ABC) transporter
J6B58_02630	COG0833	amino acid
J6B58_02675	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J6B58_02680	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J6B58_02695	COG2226	methyltransferase
J6B58_02745	COG0070	glutamate synthase
J6B58_02745	COG0069	glutamate synthase activity
J6B58_02745	COG0067	glutamate synthase
J6B58_02750	COG0493	'glutamate synthase
J6B58_02760	COG1704	LemA family
J6B58_02765	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
J6B58_02780	COG3307	-O-antigen
J6B58_02800	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J6B58_02815	COG0194	GDP metabolic process
J6B58_02865	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
J6B58_02885	COG5380	lipid catabolic process
J6B58_02890	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J6B58_02915	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J6B58_02920	COG0277	FAD linked oxidase domain protein
J6B58_02930	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
J6B58_02935	COG2249	NAD(P)H dehydrogenase (quinone) activity
J6B58_02950	COG1289	transmembrane transporter activity
J6B58_02960	COG0628	permease
J6B58_02965	COG1192	Involved in chromosome partitioning
J6B58_02995	COG0833	amino acid
J6B58_03000	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J6B58_03005	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J6B58_03015	COG1012	belongs to the aldehyde dehydrogenase family
J6B58_03055	COG0583	DNA-binding transcription factor activity
J6B58_03105	COG0517	IMP dehydrogenase activity
J6B58_03110	COG1983	PspC domain protein
J6B58_03120	COG1960	acyl-CoA dehydrogenase activity
J6B58_03140	COG0408	coproporphyrinogen oxidase activity
J6B58_03160	COG0513	Belongs to the DEAD box helicase family
J6B58_03170	COG1127	ABC transporter
J6B58_03175	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J6B58_03185	COG2854	intermembrane phospholipid transfer
J6B58_03195	COG0598	Magnesium transport protein CorA
J6B58_03205	COG0494	nUDIX hydrolase
J6B58_03210	COG1040	competence protein
J6B58_03215	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J6B58_03235	COG1946	Acyl-CoA thioesterase
J6B58_03240	COG1301	dicarboxylic acid transport
J6B58_03255	COG1959	2 iron, 2 sulfur cluster binding
J6B58_03260	COG1017	nitric oxide dioxygenase activity
J6B58_03260	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J6B58_03270	COG0433	COG0433 Predicted ATPase
J6B58_03275	COG0626	cystathionine gamma-synthase activity
J6B58_03430	COG1960	acyl-CoA dehydrogenase activity
J6B58_03435	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
J6B58_03465	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
J6B58_03470	COG0339	signal peptide processing
J6B58_03475	COG0557	exoribonuclease II activity
J6B58_03525	COG0179	Fumarylacetoacetate (FAA) hydrolase
J6B58_03530	COG2169	Transcriptional regulator
J6B58_03535	COG0697	spore germination
J6B58_03540	COG1295	ribonuclease BN
J6B58_03575	COG1702	phosphate starvation-inducible protein PhoH
J6B58_03585	COG0741	lytic transglycosylase activity
J6B58_03585	COG0739	heme binding
J6B58_03585	COG1196	nuclear chromosome segregation
J6B58_03615	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
J6B58_03620	COG1183	phosphatidylcholine synthase activity
J6B58_03665	COG1960	acyl-CoA dehydrogenase activity
J6B58_03670	COG1309	transcriptional regulator
J6B58_03685	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J6B58_03690	COG1960	acyl-CoA dehydrogenase activity
J6B58_03730	COG2969	positive regulation of protein catabolic process
J6B58_03740	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J6B58_03755	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J6B58_03760	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J6B58_03780	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J6B58_03790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J6B58_03795	COG1408	metallophosphoesterase
J6B58_03805	COG2199	diguanylate cyclase activity
J6B58_03865	COG1607	acyl-coa hydrolase
J6B58_03895	COG2350	Protein conserved in bacteria
J6B58_03905	COG0613	PHP domain protein
J6B58_03910	COG3781	membrane
J6B58_03920	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J6B58_03925	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J6B58_03935	COG1862	Preprotein translocase
J6B58_04035	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J6B58_04165	COG4695	Portal protein
J6B58_04185	COG2205	protein histidine kinase activity
J6B58_04190	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
J6B58_04210	COG0726	polysaccharide deacetylase
J6B58_04215	COG0463	Glycosyl transferase, family 2
J6B58_04220	COG0438	transferase activity, transferring glycosyl groups
J6B58_04285	COG1960	acyl-CoA dehydrogenase activity
J6B58_04290	COG1960	acyl-CoA dehydrogenase activity
J6B58_04300	COG2205	protein histidine kinase activity
J6B58_04305	COG0745	RESPONSE REGULATOR receiver
J6B58_04310	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
J6B58_04330	COG2096	Adenosyltransferase
J6B58_04380	COG0285	dihydrofolate synthase activity
J6B58_04400	COG0450	alkyl hydroperoxide reductase
J6B58_04415	COG0477	Major facilitator Superfamily
J6B58_04420	COG1272	protein, Hemolysin III
J6B58_04440	COG2153	protein acetylation
J6B58_04460	COG0183	Belongs to the thiolase family
J6B58_04465	COG2207	Transcriptional regulator
J6B58_04485	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J6B58_04505	COG0183	Belongs to the thiolase family
J6B58_04515	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
J6B58_04515	COG2885	chlorophyll binding
J6B58_04525	COG1690	Belongs to the RtcB family
J6B58_04530	COG0833	amino acid
J6B58_04540	COG2233	PERMEase
J6B58_04545	COG1217	gtp-binding protein TYPA
J6B58_04570	COG2094	Belongs to the DNA glycosylase MPG family
J6B58_04575	COG4772	TonB-dependent receptor
J6B58_04580	COG1902	pentaerythritol trinitrate reductase activity
J6B58_04595	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J6B58_04600	COG0354	folic acid binding
J6B58_04610	COG3189	MarR family transcriptional regulator
J6B58_04615	COG2824	Alkylphosphonate utilization operon protein PhnA
J6B58_04620	COG3422	double-strand break repair
J6B58_04660	COG0840	transmembrane signaling receptor activity
J6B58_04680	COG5510	response to toxic substance
J6B58_04690	COG2832	Protein of unknown function (DUF454)
J6B58_04695	COG1376	ErfK ybiS ycfS ynhG family protein
J6B58_04735	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J6B58_04745	COG1289	transmembrane transporter activity
J6B58_04750	COG2814	Major facilitator Superfamily
J6B58_04770	COG1115	amino acid carrier protein
J6B58_04775	COG1752	Esterase of the alpha-beta hydrolase superfamily
J6B58_04780	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J6B58_04785	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
J6B58_04790	COG3590	peptidase
J6B58_04815	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J6B58_04825	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J6B58_04830	COG1077	Cell shape determining protein MreB Mrl
J6B58_04835	COG1792	Involved in formation and maintenance of cell shape
J6B58_04840	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
J6B58_04845	COG0424	maF-like protein
J6B58_04850	COG1530	ribonuclease E activity
J6B58_04860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J6B58_04870	COG0560	Phosphoserine phosphatase
J6B58_04880	COG2249	NAD(P)H dehydrogenase (quinone) activity
J6B58_04905	COG2207	Transcriptional regulator
J6B58_04925	COG1113	amino acid transport
J6B58_04930	COG2828	Protein conserved in bacteria
J6B58_04935	COG0142	geranyltranstransferase activity
J6B58_04940	COG2315	Protein conserved in bacteria
J6B58_04955	COG1752	Esterase of the alpha-beta hydrolase superfamily
J6B58_04975	COG2194	sulfuric ester hydrolase activity
J6B58_04980	COG0745	RESPONSE REGULATOR receiver
J6B58_04985	COG0642	Histidine kinase
J6B58_04995	COG0004	ammonium transporteR
J6B58_05000	COG0583	DNA-binding transcription factor activity
J6B58_05020	COG0525	valine-tRNA ligase activity
J6B58_05030	COG1028	Short-chain dehydrogenase reductase Sdr
J6B58_05040	COG0393	Putative heavy-metal-binding
J6B58_05045	COG0393	Putative heavy-metal-binding
J6B58_05050	COG1538	Outer membrane efflux protein
J6B58_05060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J6B58_05065	COG0671	phosphoesterase, PA-phosphatase related
J6B58_05095	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
J6B58_05110	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J6B58_05110	COG1648	precorrin-2 dehydrogenase activity
J6B58_05115	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J6B58_05120	COG1733	regulation of RNA biosynthetic process
J6B58_05130	COG0531	amino acid
J6B58_05145	COG0321	lipoyl(octanoyl) transferase activity
J6B58_05150	COG2921	Belongs to the UPF0250 family
J6B58_05185	COG2009	succinate dehydrogenase
J6B58_05190	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
J6B58_05195	COG1053	succinate dehydrogenase
J6B58_05200	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J6B58_05225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J6B58_05245	COG2354	Protein conserved in bacteria
J6B58_05250	COG2321	neutral zinc metallopeptidase
J6B58_05275	COG2843	Capsule synthesis protein
J6B58_05290	COG0589	response to stress
J6B58_05300	COG0251	oxidation-reduction process
J6B58_05305	COG1309	transcriptional regulator
J6B58_05320	COG0505	Belongs to the CarA family
J6B58_05345	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J6B58_05350	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J6B58_05400	COG0477	Major facilitator Superfamily
J6B58_05405	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J6B58_05420	COG1597	lipid kinase activity
J6B58_05425	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
J6B58_05455	COG0584	glycerophosphoryl diester phosphodiesterase
J6B58_05475	COG0741	lytic transglycosylase activity
J6B58_05495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J6B58_05510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J6B58_05520	COG3811	Belongs to the UPF0386 family
J6B58_05540	COG0778	Nitroreductase
J6B58_05555	COG1929	Belongs to the glycerate kinase type-1 family
J6B58_05560	COG0243	molybdopterin cofactor binding
J6B58_05565	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J6B58_05570	COG3339	Conserved Protein
J6B58_05580	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
J6B58_05595	COG1113	amino acid transport
J6B58_05605	COG0019	diaminopimelate decarboxylase activity
J6B58_05615	COG1280	lysine exporter protein (LysE YggA)
J6B58_05620	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
J6B58_05650	COG0463	Glycosyl transferase, family 2
J6B58_05670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J6B58_05705	COG4591	ABC-type transport system involved in lipoprotein release permease component
J6B58_05710	COG1136	(ABC) transporter
J6B58_05715	COG0658	competence protein
J6B58_05715	COG2333	competence protein COMEC
J6B58_05725	COG0616	signal peptide processing
J6B58_05725	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J6B58_05730	COG0596	Alpha beta hydrolase
J6B58_05735	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J6B58_05745	COG0628	permease
J6B58_05780	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J6B58_05800	COG0823	Involved in the tonB-independent uptake of proteins
J6B58_05820	COG0824	Thioesterase
J6B58_05825	COG1473	amidohydrolase
J6B58_05845	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J6B58_05845	COG0047	phosphoribosylformylglycinamidine synthase activity
J6B58_05850	COG2814	Major facilitator Superfamily
J6B58_05860	COG1024	Enoyl-CoA hydratase
J6B58_05865	COG1051	belongs to the nudix hydrolase family
J6B58_05865	COG1056	cytidyltransferase-related domain
J6B58_05875	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J6B58_05890	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J6B58_05905	COG4625	pathogenesis
J6B58_05910	COG0583	DNA-binding transcription factor activity
J6B58_05915	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J6B58_05920	COG4208	sulfate ABC transporter
J6B58_05925	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
J6B58_05935	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
J6B58_05940	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J6B58_05945	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J6B58_05965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J6B58_05975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J6B58_05985	COG0681	Belongs to the peptidase S26 family
J6B58_06000	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J6B58_06010	COG1381	Involved in DNA repair and RecF pathway recombination
J6B58_06015	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J6B58_06025	COG4221	oxidoreductase activity
J6B58_06055	COG0443	Heat shock 70 kDa protein
J6B58_06065	COG0436	Aminotransferase
J6B58_06085	COG0556	nucleotide-excision repair
J6B58_06140	COG2070	2-Nitropropane dioxygenase
J6B58_06170	COG1215	transferase activity, transferring glycosyl groups
J6B58_06185	COG0415	Belongs to the DNA photolyase family
J6B58_06195	COG1252	NADH dehydrogenase
J6B58_06200	COG1686	Belongs to the peptidase S11 family
J6B58_06215	COG1187	pseudouridine synthase activity
J6B58_06285	COG3645	SOS response
J6B58_06285	COG3646	Phage regulatory protein
J6B58_06465	COG3328	transposase activity
J6B58_06565	COG0582	viral genome integration into host DNA
J6B58_06590	COG0477	Major facilitator Superfamily
J6B58_06595	COG0583	DNA-binding transcription factor activity
J6B58_06600	COG1823	symporter activity
J6B58_06610	COG0612	Peptidase, M16
J6B58_06635	COG0352	thiamine-phosphate diphosphorylase activity
J6B58_06670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J6B58_06680	COG2249	NAD(P)H dehydrogenase (quinone) activity
J6B58_06695	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J6B58_06700	COG0076	glutamate decarboxylase activity
J6B58_06710	COG1522	sequence-specific DNA binding
J6B58_06715	COG3961	Belongs to the TPP enzyme family
J6B58_06720	COG1113	amino acid transport
J6B58_06725	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J6B58_06730	COG0573	inorganic phosphate transmembrane transporter activity
J6B58_06740	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J6B58_06745	COG0616	signal peptide processing
J6B58_06780	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J6B58_06785	COG1686	Belongs to the peptidase S11 family
J6B58_06810	COG0583	DNA-binding transcription factor activity
J6B58_06815	COG1067	ATP-dependent peptidase activity
J6B58_06840	COG4943	cyclic-guanylate-specific phosphodiesterase activity
J6B58_06860	COG1966	Carbon starvation protein
J6B58_06865	COG2879	small protein
J6B58_06905	COG1335	isochorismatase
J6B58_06910	COG0583	DNA-binding transcription factor activity
J6B58_06925	COG0596	Alpha beta hydrolase
J6B58_06935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J6B58_06945	COG2130	NADP-dependent
J6B58_06975	COG1741	Belongs to the pirin family
J6B58_06985	COG2964	Protein conserved in bacteria
J6B58_07000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J6B58_07005	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J6B58_07010	COG4605	iron ion homeostasis
J6B58_07015	COG4604	ABC transporter, ATP-binding protein
J6B58_07020	COG4607	ABC-type enterochelin transport system periplasmic component
J6B58_07025	COG4774	siderophore transport
J6B58_07035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J6B58_07040	COG1021	2,3-dihydroxybenzoate-AMP ligase
J6B58_07045	COG1535	isochorismatase
J6B58_07045	COG3433	isochorismatase activity
J6B58_07060	COG1132	(ABC) transporter
J6B58_07065	COG1132	(ABC) transporter
J6B58_07070	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
J6B58_07080	COG1169	isochorismate synthase
J6B58_07095	COG3739	integral membrane protein
J6B58_07115	COG0302	gtp cyclohydrolase
J6B58_07125	COG1529	Aldehyde oxidase and xanthine dehydrogenase
J6B58_07155	COG0308	aminopeptidase N
J6B58_07160	COG0512	Glutamine amidotransferase of anthranilate synthase
J6B58_07175	COG0174	glutamine synthetase
J6B58_07185	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
J6B58_07220	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J6B58_07225	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J6B58_07230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J6B58_07250	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J6B58_07255	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J6B58_07260	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
J6B58_07275	COG1960	acyl-CoA dehydrogenase activity
J6B58_07280	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J6B58_07285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J6B58_07295	COG2223	nitrite transmembrane transporter activity
J6B58_07305	COG0024	Methionine aminopeptidase
J6B58_07310	COG0052	Belongs to the universal ribosomal protein uS2 family
J6B58_07325	COG2207	Transcriptional regulator
J6B58_07350	COG2951	lytic endotransglycosylase activity
J6B58_07355	COG0772	Belongs to the SEDS family
J6B58_07370	COG0842	Transport permease protein
J6B58_07375	COG1131	(ABC) transporter
J6B58_07415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J6B58_07430	COG4215	(ABC) transporter
J6B58_07435	COG4160	amino acid transport
J6B58_07440	COG4598	ABC transporter
J6B58_07450	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J6B58_07455	COG0826	peptidase U32
J6B58_07460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J6B58_07475	COG1720	tRNA m6t6A37 methyltransferase activity
J6B58_07485	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J6B58_07500	COG0642	Histidine kinase
J6B58_07510	COG0494	nUDIX hydrolase
J6B58_07520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J6B58_07525	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J6B58_07530	COG3139	Protein of unknown function (DUF1315)
J6B58_07535	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J6B58_07540	COG1301	dicarboxylic acid transport
J6B58_07545	COG1960	acyl-CoA dehydrogenase activity
J6B58_07550	COG2819	hydrolase of the alpha beta superfamily
J6B58_07560	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J6B58_07570	COG2195	Cleaves the N-terminal amino acid of tripeptides
J6B58_07575	COG1234	tRNA 3'-trailer cleavage
J6B58_07605	COG2363	Small membrane protein
J6B58_07625	COG0513	Belongs to the DEAD box helicase family
J6B58_07635	COG0778	Nitroreductase
J6B58_07665	COG1286	toxin biosynthetic process
J6B58_07690	COG4783	chaperone-mediated protein folding
J6B58_07695	COG1610	YqeY-like protein
J6B58_07750	COG2831	hemolysin activation secretion protein
J6B58_07865	COG3111	PFAM Bacterial OB fold (BOF) protein
J6B58_07890	COG3243	poly(R)-hydroxyalkanoic acid synthase
J6B58_07895	COG0786	glutamate:sodium symporter activity
J6B58_07905	COG2186	Transcriptional regulator
J6B58_07955	COG0477	Major facilitator Superfamily
J6B58_07980	COG2985	domain, Protein
J6B58_07995	COG2995	paraquat-inducible protein a
J6B58_08000	COG3008	intermembrane lipid transfer
J6B58_08000	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J6B58_08010	COG2351	hydroxyisourate hydrolase activity
J6B58_08050	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J6B58_08060	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J6B58_08065	COG0642	Histidine kinase
J6B58_08070	COG0745	RESPONSE REGULATOR receiver
J6B58_08090	COG1794	racemase activity, acting on amino acids and derivatives
J6B58_08120	COG1301	dicarboxylic acid transport
J6B58_08130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J6B58_08135	COG2011	ABC-type metal ion transport system permease component
J6B58_08140	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J6B58_08145	COG1464	Belongs to the NlpA lipoprotein family
J6B58_08150	COG0151	Belongs to the GarS family
J6B58_08155	COG0138	bifunctional purine biosynthesis protein purh
J6B58_08160	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
J6B58_08190	COG2308	Evidence 4 Homologs of previously reported genes of
J6B58_08200	COG1305	Transglutaminase-like
J6B58_08210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J6B58_08215	COG0305	Participates in initiation and elongation during chromosome replication
J6B58_08240	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
J6B58_08250	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J6B58_08255	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J6B58_08280	COG0726	polysaccharide deacetylase
J6B58_08280	COG1649	PFAM Uncharacterised BCR, COG1649
J6B58_08285	COG1215	transferase activity, transferring glycosyl groups
J6B58_08290	COG3658	cytochrome
J6B58_08300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J6B58_08315	COG0583	DNA-binding transcription factor activity
J6B58_08335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J6B58_08340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J6B58_08355	COG1960	acyl-CoA dehydrogenase activity
J6B58_08360	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J6B58_08365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J6B58_08390	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
J6B58_08395	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
J6B58_08405	COG2205	protein histidine kinase activity
J6B58_08410	COG0745	RESPONSE REGULATOR receiver
J6B58_08415	COG0174	glutamine synthetase
J6B58_08435	COG0729	surface antigen
J6B58_08460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J6B58_08465	COG2814	Major facilitator Superfamily
J6B58_08480	COG0583	DNA-binding transcription factor activity
J6B58_08495	COG1187	pseudouridine synthase activity
J6B58_08515	COG0802	atpase or kinase
J6B58_08520	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J6B58_08530	COG1923	regulation of RNA biosynthetic process
J6B58_08535	COG0697	spore germination
J6B58_08560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J6B58_08565	COG0519	Catalyzes the synthesis of GMP from XMP
J6B58_08565	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J6B58_08570	COG4302	ethanolamine ammonia-lyase activity
J6B58_08575	COG4303	Ethanolamine ammonia lyase large subunit
J6B58_08580	COG0531	amino acid
J6B58_08600	COG1454	alcohol dehydrogenase
J6B58_08605	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J6B58_08630	COG0308	aminopeptidase N
J6B58_08660	COG4221	oxidoreductase activity
J6B58_08670	COG1605	Chorismate mutase
J6B58_08685	COG1309	transcriptional regulator
J6B58_08695	COG0668	transmembrane transport
J6B58_08725	COG4773	Receptor
J6B58_08745	COG0488	(ABC) transporter
J6B58_08750	COG0589	response to stress
J6B58_08775	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J6B58_08785	COG3135	benzoate transporter
J6B58_08790	COG1522	sequence-specific DNA binding
J6B58_08800	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J6B58_08805	COG0583	DNA-binding transcription factor activity
J6B58_08815	COG0183	Belongs to the thiolase family
J6B58_08825	COG2030	dehydratase
J6B58_08830	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J6B58_08845	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J6B58_08855	COG0824	Thioesterase
J6B58_08860	COG1454	alcohol dehydrogenase
J6B58_08870	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J6B58_08900	COG0069	glutamate synthase activity
J6B58_08985	COG3620	sequence-specific DNA binding
J6B58_09175	COG1598	PFAM Uncharacterised protein family UPF0150
J6B58_09185	COG0739	heme binding
J6B58_09185	COG0741	lytic transglycosylase activity
J6B58_09185	COG1196	nuclear chromosome segregation
J6B58_09225	COG3179	chitinase
J6B58_09235	COG1063	alcohol dehydrogenase
J6B58_09240	COG3293	Transposase
J6B58_09275	COG2814	Major facilitator Superfamily
J6B58_09290	COG0511	ligase activity, forming carbon-carbon bonds
J6B58_09310	COG1116	anion transmembrane transporter activity
J6B58_09310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J6B58_09315	COG0745	RESPONSE REGULATOR receiver
J6B58_09325	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J6B58_09325	COG2146	nitrite reductase [NAD(P)H] activity
J6B58_09330	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J6B58_09335	COG0243	molybdopterin cofactor binding
J6B58_09345	COG0243	molybdopterin cofactor binding
J6B58_09350	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J6B58_09365	COG0315	cyclic pyranopterin monophosphate synthase activity
J6B58_09365	COG0521	Mo-molybdopterin cofactor biosynthetic process
J6B58_09380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J6B58_09385	COG0697	spore germination
J6B58_09405	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
J6B58_09410	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J6B58_09465	COG2204	response regulator
J6B58_09470	COG3852	Histidine kinase
J6B58_09495	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J6B58_09500	COG0575	Belongs to the CDS family
J6B58_09535	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J6B58_09550	COG2137	regulation of response to DNA damage stimulus
J6B58_09560	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J6B58_09565	COG1011	Hydrolase
J6B58_09590	COG1522	sequence-specific DNA binding
J6B58_09600	COG1113	amino acid transport
J6B58_09615	COG0659	secondary active sulfate transmembrane transporter activity
J6B58_09620	COG2135	peptidase activity
J6B58_09635	COG3300	MHYT domain
J6B58_09635	COG5001	Diguanylate cyclase
J6B58_09655	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J6B58_09655	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
J6B58_09655	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J6B58_09660	COG1105	Belongs to the carbohydrate kinase PfkB family
J6B58_09665	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J6B58_09665	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J6B58_09695	COG0024	Methionine aminopeptidase
J6B58_09700	COG0583	DNA-binding transcription factor activity
J6B58_09710	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J6B58_09715	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J6B58_09720	COG0516	GMP reductase activity
J6B58_09720	COG0517	IMP dehydrogenase activity
J6B58_09745	COG0552	protein localization to endoplasmic reticulum
J6B58_09755	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
J6B58_09770	COG4890	Cyd operon protein YbgT
J6B58_09775	COG1294	oxidase, subunit
J6B58_09790	COG1585	Membrane protein implicated in regulation of membrane protease activity
J6B58_09800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J6B58_09805	COG4774	siderophore transport
J6B58_09820	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J6B58_09825	COG0569	domain protein
J6B58_09830	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J6B58_09860	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
J6B58_09865	COG0542	response to heat
J6B58_09890	COG0446	pyridine nucleotide-disulphide oxidoreductase
J6B58_09890	COG1902	pentaerythritol trinitrate reductase activity
J6B58_09935	COG2323	membrane
J6B58_09940	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
J6B58_09950	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
J6B58_09955	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J6B58_09960	COG0183	Belongs to the thiolase family
J6B58_09965	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J6B58_09970	COG0596	Alpha beta hydrolase
J6B58_09975	COG2271	Major facilitator Superfamily
J6B58_09980	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J6B58_09985	COG3485	protocatechuate 3,4-dioxygenase
J6B58_09990	COG3485	protocatechuate 3,4-dioxygenase
J6B58_09995	COG0710	3-dehydroquinate dehydratase activity
J6B58_10000	COG3420	alginic acid biosynthetic process
J6B58_10005	COG3659	wide pore channel activity
J6B58_10010	COG4993	Dehydrogenase
J6B58_10020	COG2391	methyltransferase activity
J6B58_10035	COG1414	Transcriptional regulator
J6B58_10040	COG0583	DNA-binding transcription factor activity
J6B58_10045	COG1960	acyl-CoA dehydrogenase activity
J6B58_10070	COG2814	Major facilitator Superfamily
J6B58_10080	COG0154	amidase activity
J6B58_10100	COG4638	Rieske (2fe-2S)
J6B58_10110	COG1028	Short-chain dehydrogenase reductase Sdr
J6B58_10120	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J6B58_10130	COG3733	amine oxidase
J6B58_10140	COG1012	belongs to the aldehyde dehydrogenase family
J6B58_10150	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J6B58_10155	COG0183	Belongs to the thiolase family
J6B58_10160	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J6B58_10165	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
J6B58_10175	COG4829	muconolactone delta-isomerase
J6B58_10180	COG4948	Mandelate Racemase Muconate Lactonizing
J6B58_10185	COG0583	DNA-binding transcription factor activity
J6B58_10195	COG2186	Transcriptional regulator
J6B58_10215	COG1012	belongs to the aldehyde dehydrogenase family
J6B58_10230	COG0446	pyridine nucleotide-disulphide oxidoreductase
J6B58_10230	COG1902	pentaerythritol trinitrate reductase activity
J6B58_10240	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J6B58_10275	COG1309	transcriptional regulator
J6B58_10280	COG0583	DNA-binding transcription factor activity
J6B58_10285	COG1028	Short-chain dehydrogenase reductase Sdr
J6B58_10290	COG1028	Short-chain dehydrogenase reductase Sdr
J6B58_10295	COG1028	Short-chain dehydrogenase reductase Sdr
J6B58_10305	COG1960	acyl-CoA dehydrogenase activity
J6B58_10315	COG0318	PFAM AMP-dependent synthetase and ligase
J6B58_10400	COG2188	Transcriptional regulator
J6B58_10425	COG0583	DNA-binding transcription factor activity
J6B58_10460	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J6B58_10490	COG1566	PFAM secretion protein HlyD family protein
J6B58_10505	COG1012	belongs to the aldehyde dehydrogenase family
J6B58_10510	COG0129	dihydroxy-acid dehydratase activity
J6B58_10520	COG0583	DNA-binding transcription factor activity
J6B58_10525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J6B58_10535	COG2084	Dehydrogenase
J6B58_10540	COG2207	Transcriptional regulator
J6B58_10555	COG1064	alcohol dehydrogenase
J6B58_10565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J6B58_10570	COG1120	ATPase activity
J6B58_10590	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J6B58_10640	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
J6B58_10695	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
J6B58_10710	COG1028	Short-chain dehydrogenase reductase Sdr
J6B58_10720	COG2207	Transcriptional regulator
J6B58_10730	COG2205	protein histidine kinase activity
J6B58_10735	COG0745	RESPONSE REGULATOR receiver
J6B58_10740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J6B58_10745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J6B58_10820	COG3539	Fimbrial protein
J6B58_10845	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
J6B58_10855	COG0753	catalase activity
J6B58_10870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J6B58_10935	COG3433	isochorismatase activity
J6B58_10935	COG1535	isochorismatase
J6B58_10940	COG1028	Short-chain dehydrogenase reductase Sdr
J6B58_10945	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
J6B58_10950	COG4149	molybdate abc transporter
J6B58_10955	COG0725	ABC transporter, periplasmic molybdate-binding protein
J6B58_10965	COG4638	Rieske (2fe-2S)
J6B58_10970	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
J6B58_10975	COG0543	2 iron, 2 sulfur cluster binding
J6B58_10975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J6B58_10990	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J6B58_11000	COG1028	Short-chain dehydrogenase reductase Sdr
J6B58_11015	COG2207	Transcriptional regulator
J6B58_11020	COG1028	Short-chain dehydrogenase reductase Sdr
J6B58_11025	COG2610	gluconate transmembrane transporter activity
J6B58_11035	COG1309	transcriptional regulator
J6B58_11055	COG0583	DNA-binding transcription factor activity
J6B58_11070	COG2031	fatty acid transporter
J6B58_11075	COG0183	Belongs to the thiolase family
J6B58_11080	COG0583	DNA-binding transcription factor activity
J6B58_11085	COG0583	DNA-binding transcription factor activity
J6B58_11100	COG1027	Aspartate ammonia-lyase
J6B58_11110	COG0477	Major facilitator Superfamily
J6B58_11130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J6B58_11135	COG4521	taurine ABC transporter
J6B58_11150	COG2188	Transcriptional regulator
J6B58_11160	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J6B58_11165	COG1733	regulation of RNA biosynthetic process
J6B58_11170	COG2207	Transcriptional regulator
J6B58_11170	COG3708	Transcriptional regulator
J6B58_11185	COG0730	response to heat
J6B58_11195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J6B58_11195	COG3453	Protein conserved in bacteria
J6B58_11205	COG3781	membrane
J6B58_11210	COG1063	alcohol dehydrogenase
J6B58_11220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J6B58_11225	COG0508	dehydrogenase complex catalyzes the overall conversion of
J6B58_11230	COG0022	dehydrogenase e1 component
J6B58_11235	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J6B58_11240	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J6B58_11255	COG3706	GGDEF domain
J6B58_11270	COG0133	tryptophan synthase activity
J6B58_11280	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J6B58_11315	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J6B58_11340	COG2226	methyltransferase
J6B58_11395	COG0842	Transport permease protein
J6B58_11400	COG0842	Transport permease protein
J6B58_11405	COG1131	(ABC) transporter
J6B58_11420	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J6B58_11425	COG4773	Receptor
J6B58_11445	COG0730	response to heat
J6B58_11450	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J6B58_11465	COG0406	alpha-ribazole phosphatase activity
J6B58_11485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J6B58_11515	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J6B58_11525	COG4264	IucA IucC family
J6B58_11530	COG4264	IucA IucC family
J6B58_11550	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J6B58_11565	COG1960	acyl-CoA dehydrogenase activity
J6B58_11570	COG1960	acyl-CoA dehydrogenase activity
J6B58_11575	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J6B58_11580	COG2207	Transcriptional regulator
J6B58_11585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J6B58_11590	COG0776	regulation of translation
J6B58_11615	COG0822	iron-sulfur transferase activity
J6B58_11620	COG0316	Belongs to the HesB IscA family
J6B58_11650	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J6B58_11670	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J6B58_11675	COG0702	epimerase
J6B58_11710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J6B58_11720	COG0339	signal peptide processing
J6B58_11765	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J6B58_11770	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
J6B58_11800	COG0776	regulation of translation
J6B58_11865	COG0084	hydrolase, TatD family'
J6B58_11885	COG1663	tetraacyldisaccharide 4'-kinase activity
J6B58_11890	COG1132	(ABC) transporter
J6B58_11900	COG0811	peptide transport
J6B58_11905	COG1475	DNA binding
J6B58_11910	COG1192	Involved in chromosome partitioning
J6B58_11920	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J6B58_11935	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J6B58_11940	COG0191	fructose-bisphosphate aldolase activity
J6B58_11960	COG0424	maF-like protein
J6B58_11965	COG2850	peptidyl-arginine hydroxylation
J6B58_11975	COG0640	Transcriptional regulator
J6B58_11985	COG3619	membrane
J6B58_11990	COG3122	Protein conserved in bacteria
J6B58_11995	COG1132	(ABC) transporter
J6B58_12015	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J6B58_12020	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J6B58_12030	COG0506	proline dehydrogenase activity
J6B58_12030	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
J6B58_12030	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
J6B58_12035	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
J6B58_12050	COG3698	Phosphodiester glycosidase
J6B58_12060	COG2353	YceI-like domain
J6B58_12070	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J6B58_12115	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J6B58_12115	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J6B58_12140	COG3539	Fimbrial protein
J6B58_12145	COG3121	Chaperone
J6B58_12170	COG0697	spore germination
J6B58_12180	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
J6B58_12190	COG0583	DNA-binding transcription factor activity
J6B58_12210	COG1309	transcriptional regulator
J6B58_12225	COG1522	sequence-specific DNA binding
J6B58_12235	COG1126	abc transporter atp-binding protein
J6B58_12240	COG0765	amino acid transport
J6B58_12245	COG0765	amino acid transport
J6B58_12275	COG1464	Belongs to the NlpA lipoprotein family
J6B58_12285	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J6B58_12290	COG2011	ABC-type metal ion transport system permease component
J6B58_12295	COG0012	GTP binding
J6B58_12320	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
J6B58_12360	COG0386	Belongs to the glutathione peroxidase family
J6B58_12370	COG0436	Aminotransferase
J6B58_12375	COG1301	dicarboxylic acid transport
J6B58_12410	COG3634	alkyl hydroperoxide reductase activity
J6B58_12425	COG0583	DNA-binding transcription factor activity
J6B58_12430	COG0798	PFAM Bile acid sodium symporter
J6B58_12435	COG0640	Transcriptional regulator
J6B58_12450	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
J6B58_12460	COG0583	DNA-binding transcription factor activity
J6B58_12470	COG1953	Uracil, thiamine, allantoin
J6B58_12480	COG2175	clavaminate synthase activity
J6B58_12485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J6B58_12490	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
J6B58_12495	COG4521	taurine ABC transporter
J6B58_12505	COG0477	Major facilitator Superfamily
J6B58_12525	COG1271	oxidase subunit
J6B58_12530	COG1294	oxidase, subunit
J6B58_12540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J6B58_12560	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J6B58_12580	COG3052	prosthetic group binding
J6B58_12585	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
J6B58_12595	COG0583	DNA-binding transcription factor activity
J6B58_12605	COG2814	Major facilitator Superfamily
J6B58_12625	COG1346	cytolysis
J6B58_12635	COG0583	DNA-binding transcription factor activity
J6B58_12640	COG0625	glutathione transferase activity
J6B58_12645	COG0625	glutathione transferase activity
J6B58_12650	COG0583	DNA-binding transcription factor activity
J6B58_12665	COG1045	serine acetyltransferase
J6B58_12670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J6B58_12675	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J6B58_12680	COG1280	lysine exporter protein (LysE YggA)
J6B58_12690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J6B58_12695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J6B58_12705	COG0765	amino acid transport
J6B58_12710	COG0765	amino acid transport
J6B58_12730	COG0784	Response regulator, receiver
J6B58_12730	COG2205	protein histidine kinase activity
J6B58_12750	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J6B58_12770	COG1028	Short-chain dehydrogenase reductase Sdr
J6B58_12820	COG0583	DNA-binding transcription factor activity
J6B58_12840	COG0318	PFAM AMP-dependent synthetase and ligase
J6B58_12845	COG1309	transcriptional regulator
J6B58_12850	COG1960	acyl-CoA dehydrogenase activity
J6B58_12855	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J6B58_12860	COG1024	Enoyl-CoA hydratase
J6B58_12865	COG4770	biotin carboxylase activity
J6B58_12875	COG0583	DNA-binding transcription factor activity
J6B58_12890	COG1960	acyl-CoA dehydrogenase activity
J6B58_12900	COG2814	Major facilitator Superfamily
J6B58_12910	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J6B58_12915	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
J6B58_12920	COG2814	Major facilitator Superfamily
J6B58_12925	COG1960	acyl-CoA dehydrogenase activity
J6B58_12930	COG1024	Enoyl-CoA hydratase
J6B58_12935	COG1028	Short-chain dehydrogenase reductase Sdr
J6B58_12940	COG1250	3-hydroxyacyl-CoA dehydrogenase
J6B58_12945	COG0183	Belongs to the thiolase family
J6B58_12955	COG2814	Major facilitator Superfamily
J6B58_12965	COG1024	Enoyl-CoA hydratase
J6B58_12980	COG1960	acyl-CoA dehydrogenase activity
J6B58_12985	COG2814	Major facilitator Superfamily
J6B58_12990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J6B58_12995	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J6B58_13015	COG1840	ABC-type Fe3 transport system, periplasmic component
J6B58_13025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J6B58_13030	COG1414	Transcriptional regulator
J6B58_13040	COG0583	DNA-binding transcription factor activity
J6B58_13045	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J6B58_13050	COG1012	belongs to the aldehyde dehydrogenase family
J6B58_13060	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
J6B58_13070	COG1012	belongs to the aldehyde dehydrogenase family
J6B58_13075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J6B58_13080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J6B58_13085	COG2267	carboxylic ester hydrolase activity
J6B58_13105	COG3038	cytochrome b561
J6B58_13110	COG0753	catalase activity
J6B58_13115	COG2271	Major facilitator Superfamily
J6B58_13120	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J6B58_13125	COG1804	L-carnitine dehydratase bile acid-inducible protein F
J6B58_13140	COG2207	Transcriptional regulator
J6B58_13180	COG2050	protein possibly involved in aromatic compounds catabolism
J6B58_13190	COG3327	negative regulation of DNA-templated transcription, initiation
J6B58_13195	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
J6B58_13200	COG0183	Belongs to the thiolase family
J6B58_13220	COG1024	Enoyl-CoA hydratase
J6B58_13225	COG1024	Enoyl-CoA hydratase
J6B58_13230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J6B58_13235	COG2151	metal-sulfur cluster biosynthetic enzyme
J6B58_13240	COG3396	Phenylacetate-CoA oxygenase
J6B58_13245	COG3460	Phenylacetate-CoA oxygenase
J6B58_13250	COG3396	Phenylacetate-CoA oxygenase
J6B58_13255	COG1012	belongs to the aldehyde dehydrogenase family
J6B58_13255	COG2030	dehydratase
J6B58_13260	COG1760	l-serine dehydratase
J6B58_13265	COG0531	amino acid
J6B58_13270	COG1012	belongs to the aldehyde dehydrogenase family
J6B58_13295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J6B58_13315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J6B58_13325	COG0789	Transcriptional regulator
J6B58_13335	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J6B58_13350	COG2807	transmembrane transport
J6B58_13355	COG0590	tRNA wobble adenosine to inosine editing
J6B58_13470	COG1116	anion transmembrane transporter activity
J6B58_13485	COG0864	Transcriptional regulator
J6B58_13495	COG1733	regulation of RNA biosynthetic process
J6B58_13500	COG2249	NAD(P)H dehydrogenase (quinone) activity
J6B58_13505	COG0439	Biotin carboxylase
J6B58_13520	COG1063	alcohol dehydrogenase
J6B58_13530	COG1309	transcriptional regulator
J6B58_13545	COG3210	domain, Protein
J6B58_13550	COG2831	hemolysin activation secretion protein
J6B58_13555	COG0038	chloride channel
J6B58_13565	COG4770	biotin carboxylase activity
J6B58_13585	COG1914	H( )-stimulated, divalent metal cation uptake system
J6B58_13590	COG0583	DNA-binding transcription factor activity
J6B58_13660	COG1250	3-hydroxyacyl-CoA dehydrogenase
J6B58_13680	COG2814	Major facilitator Superfamily
J6B58_13690	COG1560	Kdo2-lipid A biosynthetic process
J6B58_13700	COG5006	permease, DMT superfamily
J6B58_13705	COG1522	sequence-specific DNA binding
J6B58_13720	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J6B58_13730	COG4122	O-methyltransferase activity
J6B58_13760	COG1538	Outer membrane efflux protein
J6B58_13765	COG1137	ATPase activity
J6B58_13770	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
J6B58_13780	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
J6B58_13785	COG0517	IMP dehydrogenase activity
J6B58_13785	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J6B58_13830	COG2814	Major facilitator Superfamily
J6B58_13865	COG1278	Cold shock
J6B58_13870	COG1280	lysine exporter protein (LysE YggA)
J6B58_13900	COG1570	exodeoxyribonuclease VII activity
J6B58_13980	COG2871	sodium ion transport
J6B58_13990	COG0583	DNA-binding transcription factor activity
J6B58_13995	COG4638	Rieske (2fe-2S)
J6B58_14000	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
J6B58_14005	COG0543	2 iron, 2 sulfur cluster binding
J6B58_14005	COG0633	Ferredoxin
J6B58_14010	COG1028	Short-chain dehydrogenase reductase Sdr
J6B58_14015	COG3135	benzoate transporter
J6B58_14020	COG2814	Major facilitator Superfamily
J6B58_14035	COG1643	Atp-dependent helicase
J6B58_14040	COG0450	alkyl hydroperoxide reductase
J6B58_14050	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
J6B58_14060	COG3634	alkyl hydroperoxide reductase activity
J6B58_14080	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J6B58_14085	COG0625	glutathione transferase activity
J6B58_14095	COG2885	chlorophyll binding
J6B58_14130	COG0542	response to heat
J6B58_14145	COG1765	OsmC-like protein
J6B58_14160	COG0667	Aldo Keto reductase
J6B58_14175	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J6B58_14190	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J6B58_14200	COG0582	viral genome integration into host DNA
J6B58_14220	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J6B58_14285	COG0592	DNA-directed DNA polymerase activity
J6B58_14325	COG2026	Addiction module toxin, RelE StbE family
J6B58_14475	COG3755	Protein conserved in bacteria
J6B58_14525	COG1484	DNA-dependent DNA replication
J6B58_14620	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J6B58_14660	COG0527	aspartate kinase activity
J6B58_14670	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J6B58_14680	COG3038	cytochrome b561
J6B58_14685	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J6B58_14690	COG2252	PERMEase
J6B58_14700	COG2072	flavoprotein involved in K transport
J6B58_14715	COG1741	Belongs to the pirin family
J6B58_14720	COG1309	transcriptional regulator
J6B58_14730	COG0300	oxidoreductase activity
J6B58_14735	COG2072	flavoprotein involved in K transport
J6B58_14740	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
J6B58_14785	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J6B58_14800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J6B58_14815	COG2814	Major facilitator Superfamily
J6B58_14820	COG1024	Enoyl-CoA hydratase
J6B58_14825	COG1012	belongs to the aldehyde dehydrogenase family
J6B58_14835	COG1960	acyl-CoA dehydrogenase activity
J6B58_14860	COG2186	Transcriptional regulator
J6B58_14865	COG1012	belongs to the aldehyde dehydrogenase family
J6B58_14875	COG4948	Mandelate Racemase Muconate Lactonizing
J6B58_14880	COG2271	Major facilitator Superfamily
J6B58_14885	COG2721	sulfolactate sulfo-lyase activity
J6B58_14890	COG0697	spore germination
J6B58_14925	COG1113	amino acid transport
J6B58_14945	COG1012	belongs to the aldehyde dehydrogenase family
J6B58_14965	COG0531	amino acid
J6B58_14975	COG1113	amino acid transport
J6B58_15005	COG3209	COG3209 Rhs family protein
J6B58_15030	COG4269	membrane
J6B58_15045	COG1902	pentaerythritol trinitrate reductase activity
J6B58_15045	COG0446	pyridine nucleotide-disulphide oxidoreductase
J6B58_15060	COG4251	negative regulation of phosphorylation
J6B58_15060	COG5001	Diguanylate cyclase
J6B58_15060	COG3706	GGDEF domain
J6B58_15060	COG2203	Gaf domain
J6B58_15070	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J6B58_15090	COG4172	Belongs to the ABC transporter superfamily
J6B58_15095	COG4239	(ABC) transporter, permease
J6B58_15100	COG4174	ABC transporter (Permease)
J6B58_15110	COG0741	lytic transglycosylase activity
J6B58_15110	COG0741	lytic transglycosylase activity
J6B58_15110	COG1388	LysM domain
J6B58_15110	COG1388	LysM domain
J6B58_15115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J6B58_15155	COG0583	DNA-binding transcription factor activity
J6B58_15160	COG1279	arginine transmembrane transporter activity
J6B58_15180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J6B58_15185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J6B58_15190	COG0006	proline dipeptidase activity
J6B58_15225	COG2194	sulfuric ester hydrolase activity
J6B58_15275	COG0739	heme binding
J6B58_15290	COG1598	PFAM Uncharacterised protein family UPF0150
J6B58_15450	COG0270	DNA (cytosine-5-)-methyltransferase activity
J6B58_15540	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J6B58_15565	COG3384	dioxygenase
J6B58_15575	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J6B58_15580	COG2878	Part of a membrane complex involved in electron transport
J6B58_15585	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J6B58_15610	COG0768	penicillin binding
J6B58_15615	COG0742	ribosomal rna small subunit methyltransferase
J6B58_15630	COG0830	nickel cation binding
J6B58_15675	COG1253	flavin adenine dinucleotide binding
J6B58_15680	COG2851	Citrate transporter
J6B58_15730	COG1773	rubredoxin
J6B58_15735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J6B58_15745	COG0583	DNA-binding transcription factor activity
J6B58_15775	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
J6B58_15780	COG4181	ATPase activity
J6B58_15825	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J6B58_15845	COG0306	phosphate transporter
J6B58_15855	COG3958	Transketolase
J6B58_15860	COG3959	Transketolase, thiamine diphosphate binding domain
J6B58_15865	COG2271	Major facilitator Superfamily
J6B58_15870	COG1028	Short-chain dehydrogenase reductase Sdr
J6B58_15875	COG0583	DNA-binding transcription factor activity
J6B58_15890	COG2223	nitrite transmembrane transporter activity
J6B58_15895	COG2207	Transcriptional regulator
J6B58_15900	COG2066	Belongs to the glutaminase family
J6B58_15905	COG0242	peptide deformylase activity
J6B58_15910	COG0477	Major facilitator Superfamily
J6B58_15920	COG0028	Belongs to the TPP enzyme family
J6B58_15935	COG1028	Short-chain dehydrogenase reductase Sdr
J6B58_15940	COG2267	carboxylic ester hydrolase activity
J6B58_15950	COG2271	Major facilitator Superfamily
J6B58_15955	COG0446	pyridine nucleotide-disulphide oxidoreductase
J6B58_15965	COG1028	Short-chain dehydrogenase reductase Sdr
J6B58_15985	COG1414	Transcriptional regulator
J6B58_16000	COG1024	Enoyl-CoA hydratase
J6B58_16010	COG1215	transferase activity, transferring glycosyl groups
J6B58_16015	COG0726	polysaccharide deacetylase
J6B58_16015	COG1649	PFAM Uncharacterised BCR, COG1649
J6B58_16025	COG4681	YaeQ
J6B58_16035	COG0523	cobalamin synthesis protein
J6B58_16045	COG1607	acyl-coa hydrolase
J6B58_16055	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J6B58_16060	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J6B58_16065	COG1309	transcriptional regulator
J6B58_16090	COG2040	homocysteine
J6B58_16095	COG0531	amino acid
J6B58_16150	COG1595	DNA-templated transcription, initiation
J6B58_16160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J6B58_16165	COG0477	Major facilitator Superfamily
J6B58_16225	COG0405	Gamma-glutamyltransferase
J6B58_16230	COG2814	Major facilitator Superfamily
J6B58_16240	COG2050	protein possibly involved in aromatic compounds catabolism
J6B58_16255	COG1090	epimerase
J6B58_16275	COG0420	3'-5' exonuclease activity
J6B58_16300	COG0735	belongs to the Fur family
J6B58_16305	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J6B58_16325	COG0121	glutamine amidotransferase
J6B58_16340	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J6B58_16350	COG0210	DNA helicase
J6B58_16355	COG2885	chlorophyll binding
J6B58_16360	COG0204	Acyl-transferase
J6B58_16375	COG2894	cell division
J6B58_16390	COG1280	lysine exporter protein (LysE YggA)
J6B58_16395	COG1674	ftsk spoiiie
J6B58_16395	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J6B58_16400	COG0492	ferredoxin-NADP+ reductase activity
J6B58_16405	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J6B58_16415	COG0456	acetyltransferase
J6B58_16460	COG1981	membrane
J6B58_16475	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
J6B58_16475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J6B58_16495	COG1012	belongs to the aldehyde dehydrogenase family
J6B58_16505	COG0657	acetylesterase activity
J6B58_16515	COG0473	3-isopropylmalate dehydrogenase activity
J6B58_16520	COG0583	DNA-binding transcription factor activity
J6B58_16540	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J6B58_16565	COG0564	pseudouridine synthase activity
J6B58_16575	COG0358	DNA primase activity
J6B58_16590	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
J6B58_16620	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J6B58_16650	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J6B58_16660	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J6B58_16660	COG0352	thiamine-phosphate diphosphorylase activity
J6B58_16660	COG0351	phosphomethylpyrimidine kinase
J6B58_16665	COG1652	LysM domain
J6B58_16690	COG1399	metal-binding, possibly nucleic acid-binding protein
J6B58_16695	COG3101	peptidyl-lysine hydroxylation
J6B58_16700	COG0009	L-threonylcarbamoyladenylate synthase
J6B58_16705	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
J6B58_16710	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
J6B58_16725	COG4106	trans-aconitate 2-methyltransferase activity
J6B58_16740	COG2226	methyltransferase
J6B58_16740	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J6B58_16740	COG0596	Alpha beta hydrolase
J6B58_16745	COG1877	trehalose-phosphatase activity
J6B58_16750	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
J6B58_16755	COG2223	nitrite transmembrane transporter activity
J6B58_16775	COG1196	nuclear chromosome segregation
J6B58_16785	COG0730	response to heat
J6B58_16800	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J6B58_16810	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J6B58_16860	COG0489	protein tyrosine kinase activity
J6B58_16870	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J6B58_16870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J6B58_16900	COG2515	1-aminocyclopropane-1-carboxylate deaminase
J6B58_16905	COG2081	HI0933 family
J6B58_16915	COG0668	transmembrane transport
J6B58_16935	COG0583	DNA-binding transcription factor activity
J6B58_16960	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J6B58_16965	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J6B58_16995	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
J6B58_17035	COG0745	RESPONSE REGULATOR receiver
J6B58_17055	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J6B58_17060	COG0697	spore germination
J6B58_17095	COG0477	Major facilitator Superfamily
J6B58_17105	COG1028	Short-chain dehydrogenase reductase Sdr
J6B58_17150	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J6B58_17185	COG0583	DNA-binding transcription factor activity
J6B58_17200	COG0583	DNA-binding transcription factor activity
J6B58_17205	COG1053	succinate dehydrogenase
J6B58_17215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
J6B58_17220	COG2814	Major facilitator Superfamily
J6B58_17225	COG1960	acyl-CoA dehydrogenase activity
J6B58_17230	COG0583	DNA-binding transcription factor activity
J6B58_17235	COG1063	alcohol dehydrogenase
J6B58_17265	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J6B58_17270	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
J6B58_17275	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J6B58_17295	COG2132	Multicopper oxidase
J6B58_17305	COG0561	phosphatase activity
J6B58_17310	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J6B58_17320	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
J6B58_17335	COG1214	PFAM Peptidase M22, glycoprotease
J6B58_17395	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J6B58_17405	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J6B58_17410	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
J6B58_17415	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J6B58_17475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J6B58_17485	COG1846	Transcriptional regulator
J6B58_17490	COG1764	response to oxidative stress
J6B58_17530	COG0037	tRNA processing
J6B58_17540	COG0248	Ppx GppA phosphatase
J6B58_17570	COG0072	phenylalanine-tRNA ligase activity
J6B58_17610	COG1238	metal cluster binding
J6B58_17615	COG0625	glutathione transferase activity
J6B58_17630	COG0318	PFAM AMP-dependent synthetase and ligase
J6B58_17635	COG3028	Belongs to the UPF0307 family
J6B58_17640	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J6B58_17660	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J6B58_17665	COG0617	tRNA 3'-terminal CCA addition
J6B58_17670	COG1555	photosystem II stabilization
J6B58_17675	COG3956	TIGRFAM MazG family protein
J6B58_17685	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J6B58_17705	COG2205	protein histidine kinase activity
J6B58_17705	COG5002	protein histidine kinase activity
J6B58_17705	COG0784	Response regulator, receiver
J6B58_17710	COG1024	Enoyl-CoA hydratase
J6B58_17715	COG2084	Dehydrogenase
J6B58_17720	COG3622	Belongs to the hyi family
J6B58_17750	COG0697	spore germination
J6B58_17760	COG2814	Major facilitator Superfamily
J6B58_17780	COG2132	Multicopper oxidase
J6B58_17795	COG2205	protein histidine kinase activity
J6B58_17885	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J6B58_17895	COG0583	DNA-binding transcription factor activity
J6B58_17905	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J6B58_17915	COG0084	hydrolase, TatD family'
J6B58_17930	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
J6B58_17965	COG0440	acetolactate synthase activity
J6B58_17970	COG0028	Belongs to the TPP enzyme family
J6B58_17995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J6B58_18000	COG0577	efflux transmembrane transporter activity
J6B58_18000	COG1136	(ABC) transporter
J6B58_18005	COG1538	Outer membrane efflux protein
J6B58_18020	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
J6B58_18025	COG1162	GTPase activity
J6B58_18035	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J6B58_18075	COG1426	Protein conserved in bacteria
J6B58_18110	COG0793	Belongs to the peptidase S41A family
J6B58_18125	COG2267	carboxylic ester hydrolase activity
J6B58_18135	COG1012	belongs to the aldehyde dehydrogenase family
J6B58_18140	COG3265	gluconokinase activity
J6B58_18150	COG0800	Aldolase
J6B58_18160	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J6B58_18165	COG0857	belongs to the CobB CobQ family
J6B58_18165	COG0280	phosphate acetyltransferase
J6B58_18170	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
J6B58_18170	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
J6B58_18190	COG0740	serine-type endopeptidase activity
J6B58_18200	COG4774	siderophore transport
J6B58_18210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J6B58_18220	COG2813	Specifically methylates the guanine in position
J6B58_18220	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J6B58_18320	COG0788	formyltetrahydrofolate deformylase activity
J6B58_18345	COG4651	solute:proton antiporter activity
J6B58_18345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J6B58_18365	COG0724	RNA recognition motif
J6B58_18370	COG0210	DNA helicase
J6B58_18395	COG1733	regulation of RNA biosynthetic process
J6B58_18405	COG2900	Belongs to the SlyX family
J6B58_18410	COG0488	(ABC) transporter
J6B58_18415	COG1280	lysine exporter protein (LysE YggA)
J6B58_18420	COG1560	Kdo2-lipid A biosynthetic process
J6B58_18430	COG1301	dicarboxylic acid transport
J6B58_18485	COG0473	3-isopropylmalate dehydrogenase activity
J6B58_18570	COG0625	glutathione transferase activity
J6B58_18575	COG2378	regulation of single-species biofilm formation
J6B58_18580	COG0546	phosphoglycolate phosphatase activity
J6B58_18590	COG1530	ribonuclease E activity
J6B58_18595	COG0318	PFAM AMP-dependent synthetase and ligase
J6B58_18610	COG0583	DNA-binding transcription factor activity
J6B58_18615	COG4221	oxidoreductase activity
J6B58_18620	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J6B58_18630	COG0534	Mate efflux family protein
J6B58_18645	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J6B58_18670	COG0493	'glutamate synthase
J6B58_18670	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
J6B58_18680	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
J6B58_18685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J6B58_18700	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J6B58_18710	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
J6B58_18710	COG0644	oxidoreductase
J6B58_18720	COG0425	Belongs to the sulfur carrier protein TusA family
J6B58_18725	COG4535	Mg2 and Co2 transporter CorC
J6B58_18735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J6B58_18755	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J6B58_18760	COG0475	glutathione-regulated potassium exporter activity
J6B58_18760	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J6B58_18775	COG0484	heat shock protein binding
J6B58_18780	COG0789	Transcriptional regulator
J6B58_18785	COG0598	Magnesium transport protein CorA
J6B58_18800	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J6B58_18805	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J6B58_18810	COG1074	ATP-dependent DNA helicase activity
J6B58_18815	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
J6B58_18835	COG2226	methyltransferase
J6B58_18855	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J6B58_18870	COG2111	Na H antiporter
J6B58_18870	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J6B58_18875	COG1006	Multisubunit Na H antiporter MnhC subunit
J6B58_18880	COG0651	ATP synthesis coupled electron transport
J6B58_18885	COG1863	multisubunit Na H antiporter MnhE subunit
J6B58_18890	COG2212	antiporter activity
J6B58_18895	COG1320	monovalent cation:proton antiporter activity
J6B58_18910	COG0195	Participates in both transcription termination and antitermination
J6B58_18960	COG0237	dephospho-CoA kinase activity
J6B58_18970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J6B58_18985	COG0497	DNA recombination
J6B58_18995	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J6B58_19025	COG2169	Transcriptional regulator
J6B58_19025	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J6B58_19030	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J6B58_19095	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
J6B58_19110	COG0326	Molecular chaperone. Has ATPase activity
J6B58_19125	COG2056	Na+-H+ antiporter family
J6B58_19130	COG0596	Alpha beta hydrolase
J6B58_19225	COG0546	phosphoglycolate phosphatase activity
J6B58_19230	COG1716	ATPase activity
J6B58_19275	COG0181	hydroxymethylbilane synthase activity
J6B58_19285	COG3275	phosphorelay sensor kinase activity
J6B58_19305	COG1538	Outer membrane efflux protein
J6B58_19310	COG0697	spore germination
J6B58_19335	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
J6B58_19340	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J6B58_19345	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J6B58_19350	COG0772	Belongs to the SEDS family
J6B58_19375	COG4974	Belongs to the 'phage' integrase family
J6B58_19380	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J6B58_19390	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
J6B58_19400	COG2197	response regulator
J6B58_19415	COG0793	Belongs to the peptidase S41A family
J6B58_19420	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
J6B58_19425	COG0795	lipopolysaccharide-transporting ATPase activity
J6B58_19465	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J6B58_19465	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J6B58_19475	COG0004	ammonium transporteR
J6B58_19480	COG0347	Belongs to the P(II) protein family
J6B58_19505	COG3173	Aminoglycoside phosphotransferase
J6B58_19510	COG0488	(ABC) transporter
J6B58_19525	COG0482	sulfurtransferase activity
J6B58_19670	COG1192	Involved in chromosome partitioning
J6B58_19700	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J6B58_19705	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J6B58_19745	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J6B58_19885	COG0583	DNA-binding transcription factor activity
J6B58_19910	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
J6B58_19920	COG0659	secondary active sulfate transmembrane transporter activity
J6B58_19975	COG1373	ATPase (AAA superfamily
J6B58_20015	COG1309	transcriptional regulator
J6B58_20040	COG0633	Ferredoxin
J6B58_20045	COG2207	Transcriptional regulator
J6B58_20200	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J6B58_20250	COG1192	Involved in chromosome partitioning
J6B58_20260	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J6B58_20300	COG0739	heme binding
J6B58_20535	COG0501	Belongs to the peptidase M48B family
J6B58_20570	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
J6B58_20640	COG1525	nuclease
J6B58_20700	COG1475	DNA binding
J6B58_20715	COG3853	Toxic anion resistance protein (TelA)
J6B58_20800	COG0484	heat shock protein binding
J6B58_20855	COG0589	response to stress
J6B58_20860	COG0659	secondary active sulfate transmembrane transporter activity
J6B58_20945	COG2826	transposase and inactivated derivatives, IS30 family
J6B58_20955	COG2826	transposase and inactivated derivatives, IS30 family
J6B58_20980	COG0741	lytic transglycosylase activity
J6B58_21015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J6B58_21100	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J6B58_21135	COG4683	PFAM Phage derived protein Gp49-like (DUF891)