locus-tag	class	description
NHY62_00045	COG0657	acetylesterase activity
NHY62_00050	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NHY62_00090	COG1047	Peptidyl-prolyl cis-trans
NHY62_00105	COG0196	riboflavin kinase activity
NHY62_00120	COG1309	transcriptional regulator
NHY62_00125	COG1116	anion transmembrane transporter activity
NHY62_00130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NHY62_00135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHY62_00140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NHY62_00145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NHY62_00165	COG1028	Short-chain dehydrogenase reductase Sdr
NHY62_00170	COG0546	phosphoglycolate phosphatase activity
NHY62_00225	COG3023	N-Acetylmuramoyl-L-alanine amidase
NHY62_00255	COG1596	polysaccharide export
NHY62_00265	COG1086	Polysaccharide biosynthesis protein
NHY62_00270	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NHY62_00275	COG1083	cytidylyl-transferase
NHY62_00325	COG1216	Glycosyl transferase, family 2
NHY62_00330	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NHY62_00335	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NHY62_00350	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NHY62_00355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NHY62_00375	COG0277	FAD linked oxidase domain protein
NHY62_00380	COG1448	Aminotransferase
NHY62_00385	COG1802	Transcriptional regulator
NHY62_00460	COG0564	pseudouridine synthase activity
NHY62_00500	COG0251	oxidation-reduction process
NHY62_00505	COG1113	amino acid transport
NHY62_00530	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NHY62_00535	COG1960	acyl-CoA dehydrogenase activity
NHY62_00540	COG1024	Enoyl-CoA hydratase
NHY62_00545	COG1024	Enoyl-CoA hydratase
NHY62_00555	COG3916	Acyl-homoserine-lactone synthase
NHY62_00565	COG2197	response regulator
NHY62_00575	COG1960	acyl-CoA dehydrogenase activity
NHY62_00580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHY62_00580	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NHY62_00580	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NHY62_00580	COG3321	synthase
NHY62_00600	COG2267	carboxylic ester hydrolase activity
NHY62_00620	COG0271	Belongs to the BolA IbaG family
NHY62_00630	COG1192	Involved in chromosome partitioning
NHY62_00645	COG0586	Pfam SNARE associated Golgi protein
NHY62_00655	COG4399	Belongs to the UPF0754 family
NHY62_00660	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NHY62_00660	COG0519	Catalyzes the synthesis of GMP from XMP
NHY62_00705	COG0281	malic enzyme
NHY62_00720	COG1280	lysine exporter protein (LysE YggA)
NHY62_00795	COG0386	Belongs to the glutathione peroxidase family
NHY62_00810	COG1309	transcriptional regulator
NHY62_00815	COG0697	spore germination
NHY62_00825	COG0758	DNA mediated transformation
NHY62_00895	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NHY62_00945	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHY62_00965	COG1253	flavin adenine dinucleotide binding
NHY62_00990	COG0318	PFAM AMP-dependent synthetase and ligase
NHY62_01005	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NHY62_01025	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NHY62_01035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NHY62_01085	COG1002	Type II restriction enzyme, methylase subunits
NHY62_01090	COG1061	Type III restriction enzyme res subunit
NHY62_01135	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NHY62_01180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NHY62_01225	COG0659	secondary active sulfate transmembrane transporter activity
NHY62_01285	COG0347	Belongs to the P(II) protein family
NHY62_01300	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NHY62_01300	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NHY62_01345	COG0795	lipopolysaccharide-transporting ATPase activity
NHY62_01370	COG2197	response regulator
NHY62_01390	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NHY62_01425	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NHY62_01430	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NHY62_01435	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NHY62_01460	COG0697	spore germination
NHY62_01465	COG1538	Outer membrane efflux protein
NHY62_01485	COG3275	phosphorelay sensor kinase activity
NHY62_01495	COG0181	hydroxymethylbilane synthase activity
NHY62_01540	COG1716	ATPase activity
NHY62_01545	COG0546	phosphoglycolate phosphatase activity
NHY62_01740	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NHY62_01775	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NHY62_01800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHY62_01810	COG0237	dephospho-CoA kinase activity
NHY62_01815	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NHY62_01880	COG1320	monovalent cation:proton antiporter activity
NHY62_01885	COG2212	antiporter activity
NHY62_01890	COG1863	multisubunit Na H antiporter MnhE subunit
NHY62_01895	COG0651	ATP synthesis coupled electron transport
NHY62_01900	COG1006	Multisubunit Na H antiporter MnhC subunit
NHY62_01905	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NHY62_01905	COG2111	Na H antiporter
NHY62_01920	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NHY62_01925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NHY62_01940	COG2226	methyltransferase
NHY62_01970	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NHY62_01975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NHY62_01990	COG0598	Magnesium transport protein CorA
NHY62_01995	COG0789	Transcriptional regulator
NHY62_02000	COG0484	heat shock protein binding
NHY62_02010	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NHY62_02040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NHY62_02050	COG4535	Mg2 and Co2 transporter CorC
NHY62_02055	COG0425	Belongs to the sulfur carrier protein TusA family
NHY62_02070	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NHY62_02085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NHY62_02090	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
NHY62_02130	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NHY62_02145	COG0534	Mate efflux family protein
NHY62_02155	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NHY62_02160	COG4221	oxidoreductase activity
NHY62_02165	COG0583	DNA-binding transcription factor activity
NHY62_02180	COG0318	PFAM AMP-dependent synthetase and ligase
NHY62_02185	COG1530	ribonuclease E activity
NHY62_02195	COG0546	phosphoglycolate phosphatase activity
NHY62_02205	COG0625	glutathione transferase activity
NHY62_02280	COG0473	3-isopropylmalate dehydrogenase activity
NHY62_02335	COG1301	dicarboxylic acid transport
NHY62_02345	COG1560	Kdo2-lipid A biosynthetic process
NHY62_02350	COG1280	lysine exporter protein (LysE YggA)
NHY62_02355	COG0488	(ABC) transporter
NHY62_02360	COG2900	Belongs to the SlyX family
NHY62_02370	COG1733	regulation of RNA biosynthetic process
NHY62_02395	COG0210	DNA helicase
NHY62_02400	COG0724	RNA recognition motif
NHY62_02420	COG4651	solute:proton antiporter activity
NHY62_02420	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NHY62_02445	COG0788	formyltetrahydrofolate deformylase activity
NHY62_02555	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NHY62_02575	COG0740	serine-type endopeptidase activity
NHY62_02595	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
NHY62_02595	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
NHY62_02600	COG0280	phosphate acetyltransferase
NHY62_02600	COG0857	belongs to the CobB CobQ family
NHY62_02615	COG0800	Aldolase
NHY62_02625	COG3265	gluconokinase activity
NHY62_02630	COG1012	belongs to the aldehyde dehydrogenase family
NHY62_02640	COG2267	carboxylic ester hydrolase activity
NHY62_02690	COG1426	Protein conserved in bacteria
NHY62_02735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHY62_02745	COG0318	PFAM AMP-dependent synthetase and ligase
NHY62_02760	COG2986	histidine ammonia-lyase
NHY62_02800	COG1028	Short-chain dehydrogenase reductase Sdr
NHY62_02805	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NHY62_02825	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NHY62_02835	COG1162	GTPase activity
NHY62_02840	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NHY62_02855	COG1538	Outer membrane efflux protein
NHY62_02860	COG1136	(ABC) transporter
NHY62_02860	COG0577	efflux transmembrane transporter activity
NHY62_02865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NHY62_02890	COG0028	Belongs to the TPP enzyme family
NHY62_02895	COG0440	acetolactate synthase activity
NHY62_02935	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NHY62_02950	COG0084	hydrolase, TatD family'
NHY62_02965	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NHY62_02975	COG0583	DNA-binding transcription factor activity
NHY62_02985	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NHY62_02990	COG2814	Major facilitator Superfamily
NHY62_03000	COG0697	spore germination
NHY62_03030	COG3622	Belongs to the hyi family
NHY62_03035	COG2084	Dehydrogenase
NHY62_03040	COG1024	Enoyl-CoA hydratase
NHY62_03045	COG0784	Response regulator, receiver
NHY62_03045	COG5002	protein histidine kinase activity
NHY62_03045	COG2205	protein histidine kinase activity
NHY62_03065	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NHY62_03075	COG3956	TIGRFAM MazG family protein
NHY62_03080	COG1555	photosystem II stabilization
NHY62_03085	COG0617	tRNA 3'-terminal CCA addition
NHY62_03090	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NHY62_03110	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NHY62_03135	COG0625	glutathione transferase activity
NHY62_03140	COG1238	metal cluster binding
NHY62_03215	COG0248	Ppx GppA phosphatase
NHY62_03265	COG1764	response to oxidative stress
NHY62_03270	COG1846	Transcriptional regulator
NHY62_03280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NHY62_03340	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHY62_03345	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NHY62_03360	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NHY62_03410	COG1214	PFAM Peptidase M22, glycoprotease
NHY62_03435	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NHY62_03440	COG0561	phosphatase activity
NHY62_03470	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NHY62_03475	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NHY62_03510	COG1063	alcohol dehydrogenase
NHY62_03515	COG0583	DNA-binding transcription factor activity
NHY62_03525	COG2814	Major facilitator Superfamily
NHY62_03530	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NHY62_03540	COG1053	succinate dehydrogenase
NHY62_03545	COG0583	DNA-binding transcription factor activity
NHY62_03560	COG0583	DNA-binding transcription factor activity
NHY62_03605	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NHY62_03635	COG0384	phenazine biosynthesis protein PhzF
NHY62_03660	COG4993	Dehydrogenase
NHY62_03725	COG2205	protein histidine kinase activity
NHY62_03740	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHY62_03760	COG0745	RESPONSE REGULATOR receiver
NHY62_03800	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NHY62_03835	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NHY62_03855	COG0583	DNA-binding transcription factor activity
NHY62_03875	COG0668	transmembrane transport
NHY62_03890	COG2515	1-aminocyclopropane-1-carboxylate deaminase
NHY62_03980	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NHY62_04005	COG0730	response to heat
NHY62_04015	COG1196	nuclear chromosome segregation
NHY62_04035	COG2223	nitrite transmembrane transporter activity
NHY62_04040	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
NHY62_04045	COG1877	trehalose-phosphatase activity
NHY62_04050	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NHY62_04050	COG2226	methyltransferase
NHY62_04050	COG0596	Alpha beta hydrolase
NHY62_04065	COG4106	trans-aconitate 2-methyltransferase activity
NHY62_04080	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NHY62_04085	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NHY62_04090	COG0009	L-threonylcarbamoyladenylate synthase
NHY62_04095	COG3101	peptidyl-lysine hydroxylation
NHY62_04100	COG1399	metal-binding, possibly nucleic acid-binding protein
NHY62_04125	COG1652	LysM domain
NHY62_04130	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NHY62_04130	COG0352	thiamine-phosphate diphosphorylase activity
NHY62_04130	COG0351	phosphomethylpyrimidine kinase
NHY62_04140	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NHY62_04170	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHY62_04200	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NHY62_04225	COG0564	pseudouridine synthase activity
NHY62_04250	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NHY62_04270	COG0583	DNA-binding transcription factor activity
NHY62_04275	COG0473	3-isopropylmalate dehydrogenase activity
NHY62_04285	COG0657	acetylesterase activity
NHY62_04330	COG1981	membrane
NHY62_04375	COG0456	acetyltransferase
NHY62_04385	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NHY62_04395	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NHY62_04395	COG1674	ftsk spoiiie
NHY62_04420	COG2894	cell division
NHY62_04435	COG0204	Acyl-transferase
NHY62_04440	COG2885	chlorophyll binding
NHY62_04445	COG0210	DNA helicase
NHY62_04455	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NHY62_04470	COG0121	glutamine amidotransferase
NHY62_04490	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NHY62_04495	COG0735	belongs to the Fur family
NHY62_04520	COG0420	3'-5' exonuclease activity
NHY62_04540	COG1090	epimerase
NHY62_04555	COG2050	protein possibly involved in aromatic compounds catabolism
NHY62_04640	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NHY62_04730	COG1484	DNA-dependent DNA replication
NHY62_04780	COG3755	Protein conserved in bacteria
NHY62_04940	COG2026	Addiction module toxin, RelE StbE family
NHY62_04985	COG0592	DNA-directed DNA polymerase activity
NHY62_05145	COG2040	homocysteine
NHY62_05170	COG1309	transcriptional regulator
NHY62_05200	COG0523	cobalamin synthesis protein
NHY62_05210	COG4681	YaeQ
NHY62_05220	COG0726	polysaccharide deacetylase
NHY62_05220	COG1649	PFAM Uncharacterised BCR, COG1649
NHY62_05225	COG1215	transferase activity, transferring glycosyl groups
NHY62_05235	COG1024	Enoyl-CoA hydratase
NHY62_05250	COG1414	Transcriptional regulator
NHY62_05270	COG1028	Short-chain dehydrogenase reductase Sdr
NHY62_05280	COG0446	pyridine nucleotide-disulphide oxidoreductase
NHY62_05285	COG2271	Major facilitator Superfamily
NHY62_05295	COG2267	carboxylic ester hydrolase activity
NHY62_05300	COG1028	Short-chain dehydrogenase reductase Sdr
NHY62_05315	COG0028	Belongs to the TPP enzyme family
NHY62_05325	COG0477	Major facilitator Superfamily
NHY62_05330	COG0242	peptide deformylase activity
NHY62_05335	COG2066	Belongs to the glutaminase family
NHY62_05340	COG2207	Transcriptional regulator
NHY62_05345	COG2223	nitrite transmembrane transporter activity
NHY62_05360	COG0583	DNA-binding transcription factor activity
NHY62_05365	COG1028	Short-chain dehydrogenase reductase Sdr
NHY62_05370	COG2271	Major facilitator Superfamily
NHY62_05375	COG3959	Transketolase, thiamine diphosphate binding domain
NHY62_05380	COG3958	Transketolase
NHY62_05390	COG0306	phosphate transporter
NHY62_05410	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NHY62_05455	COG4181	ATPase activity
NHY62_05460	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
NHY62_05495	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NHY62_05500	COG1773	rubredoxin
NHY62_05550	COG2851	Citrate transporter
NHY62_05595	COG0804	urea catabolic process
NHY62_05610	COG0830	nickel cation binding
NHY62_05625	COG0742	ribosomal rna small subunit methyltransferase
NHY62_05660	COG2878	Part of a membrane complex involved in electron transport
NHY62_05665	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NHY62_05675	COG3384	dioxygenase
NHY62_05700	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NHY62_06070	COG2194	sulfuric ester hydrolase activity
NHY62_06110	COG0006	proline dipeptidase activity
NHY62_06120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NHY62_06185	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NHY62_06205	COG4239	(ABC) transporter, permease
NHY62_06230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NHY62_06240	COG5001	Diguanylate cyclase
NHY62_06240	COG4251	negative regulation of phosphorylation
NHY62_06240	COG3706	GGDEF domain
NHY62_06240	COG2203	Gaf domain
NHY62_06250	COG1902	pentaerythritol trinitrate reductase activity
NHY62_06250	COG0446	pyridine nucleotide-disulphide oxidoreductase
NHY62_06265	COG4269	membrane
NHY62_06345	COG0531	amino acid
NHY62_06365	COG1012	belongs to the aldehyde dehydrogenase family
NHY62_06400	COG0300	oxidoreductase activity
NHY62_06410	COG1309	transcriptional regulator
NHY62_06415	COG1741	Belongs to the pirin family
NHY62_06430	COG2072	flavoprotein involved in K transport
NHY62_06440	COG2252	PERMEase
NHY62_06445	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NHY62_06450	COG3038	cytochrome b561
NHY62_06460	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHY62_06470	COG0527	aspartate kinase activity
NHY62_06480	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NHY62_06490	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NHY62_06505	COG0667	Aldo Keto reductase
NHY62_06525	COG1765	OsmC-like protein
NHY62_06545	COG0542	response to heat
NHY62_06590	COG0625	glutathione transferase activity
NHY62_06615	COG3634	alkyl hydroperoxide reductase activity
NHY62_06625	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NHY62_06635	COG0450	alkyl hydroperoxide reductase
NHY62_06655	COG2814	Major facilitator Superfamily
NHY62_06660	COG3135	benzoate transporter
NHY62_06665	COG1028	Short-chain dehydrogenase reductase Sdr
NHY62_06670	COG0543	2 iron, 2 sulfur cluster binding
NHY62_06670	COG0633	Ferredoxin
NHY62_06675	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
NHY62_06680	COG4638	Rieske (2fe-2S)
NHY62_06690	COG0583	DNA-binding transcription factor activity
NHY62_06740	COG1570	exodeoxyribonuclease VII activity
NHY62_06770	COG1280	lysine exporter protein (LysE YggA)
NHY62_06775	COG1278	Cold shock
NHY62_06810	COG2814	Major facilitator Superfamily
NHY62_06850	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NHY62_06860	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NHY62_06865	COG1137	ATPase activity
NHY62_06900	COG4122	O-methyltransferase activity
NHY62_06925	COG1522	sequence-specific DNA binding
NHY62_06930	COG5006	permease, DMT superfamily
NHY62_06955	COG2814	Major facilitator Superfamily
NHY62_07050	COG4770	biotin carboxylase activity
NHY62_07055	COG0038	chloride channel
NHY62_07075	COG1309	transcriptional regulator
NHY62_07085	COG1063	alcohol dehydrogenase
NHY62_07100	COG0439	Biotin carboxylase
NHY62_07105	COG2249	NAD(P)H dehydrogenase (quinone) activity
NHY62_07125	COG0864	Transcriptional regulator
NHY62_07135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NHY62_07140	COG1116	anion transmembrane transporter activity
NHY62_07260	COG0590	tRNA wobble adenosine to inosine editing
NHY62_07295	COG0789	Transcriptional regulator
NHY62_07305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NHY62_07350	COG1012	belongs to the aldehyde dehydrogenase family
NHY62_07355	COG0531	amino acid
NHY62_07360	COG1760	l-serine dehydratase
NHY62_07365	COG1012	belongs to the aldehyde dehydrogenase family
NHY62_07365	COG2030	dehydratase
NHY62_07370	COG3396	Phenylacetate-CoA oxygenase
NHY62_07375	COG3460	Phenylacetate-CoA oxygenase
NHY62_07380	COG3396	Phenylacetate-CoA oxygenase
NHY62_07385	COG2151	metal-sulfur cluster biosynthetic enzyme
NHY62_07390	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NHY62_07395	COG1024	Enoyl-CoA hydratase
NHY62_07410	COG0183	Belongs to the thiolase family
NHY62_07415	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NHY62_07420	COG3327	negative regulation of DNA-templated transcription, initiation
NHY62_07430	COG2050	protein possibly involved in aromatic compounds catabolism
NHY62_07465	COG0753	catalase activity
NHY62_07470	COG3038	cytochrome b561
NHY62_07500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHY62_07505	COG1012	belongs to the aldehyde dehydrogenase family
NHY62_07515	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NHY62_07525	COG1012	belongs to the aldehyde dehydrogenase family
NHY62_07535	COG0583	DNA-binding transcription factor activity
NHY62_07545	COG1414	Transcriptional regulator
NHY62_07550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NHY62_07560	COG1840	ABC-type Fe3 transport system, periplasmic component
NHY62_07565	COG3842	ATPase activity
NHY62_07580	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NHY62_07585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NHY62_07590	COG2814	Major facilitator Superfamily
NHY62_07595	COG1960	acyl-CoA dehydrogenase activity
NHY62_07610	COG1024	Enoyl-CoA hydratase
NHY62_07620	COG2814	Major facilitator Superfamily
NHY62_07635	COG1250	3-hydroxyacyl-CoA dehydrogenase
NHY62_07640	COG1028	Short-chain dehydrogenase reductase Sdr
NHY62_07645	COG1024	Enoyl-CoA hydratase
NHY62_07650	COG1960	acyl-CoA dehydrogenase activity
NHY62_07655	COG2814	Major facilitator Superfamily
NHY62_07660	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NHY62_07665	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NHY62_07675	COG2814	Major facilitator Superfamily
NHY62_07685	COG1960	acyl-CoA dehydrogenase activity
NHY62_07700	COG0583	DNA-binding transcription factor activity
NHY62_07710	COG4770	biotin carboxylase activity
NHY62_07715	COG1024	Enoyl-CoA hydratase
NHY62_07720	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NHY62_07730	COG1309	transcriptional regulator
NHY62_07805	COG1028	Short-chain dehydrogenase reductase Sdr
NHY62_07825	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NHY62_07845	COG2205	protein histidine kinase activity
NHY62_07845	COG0784	Response regulator, receiver
NHY62_07865	COG0765	amino acid transport
NHY62_07870	COG0765	amino acid transport
NHY62_07880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NHY62_07885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NHY62_07910	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NHY62_07920	COG1045	serine acetyltransferase
NHY62_07935	COG0583	DNA-binding transcription factor activity
NHY62_07940	COG0625	glutathione transferase activity
NHY62_07945	COG0625	glutathione transferase activity
NHY62_07950	COG0583	DNA-binding transcription factor activity
NHY62_07960	COG1346	cytolysis
NHY62_07980	COG2814	Major facilitator Superfamily
NHY62_07990	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
NHY62_07995	COG3052	prosthetic group binding
NHY62_08015	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NHY62_08035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NHY62_08045	COG1294	oxidase, subunit
NHY62_08080	COG4521	taurine ABC transporter
NHY62_08090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NHY62_08095	COG2175	clavaminate synthase activity
NHY62_08115	COG0583	DNA-binding transcription factor activity
NHY62_08125	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NHY62_08140	COG0640	Transcriptional regulator
NHY62_08145	COG0798	PFAM Bile acid sodium symporter
NHY62_08150	COG0583	DNA-binding transcription factor activity
NHY62_08165	COG3634	alkyl hydroperoxide reductase activity
NHY62_08200	COG1301	dicarboxylic acid transport
NHY62_08205	COG0436	Aminotransferase
NHY62_08215	COG0386	Belongs to the glutathione peroxidase family
NHY62_08280	COG0012	GTP binding
NHY62_08290	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NHY62_08300	COG1464	Belongs to the NlpA lipoprotein family
NHY62_08330	COG0765	amino acid transport
NHY62_08340	COG1126	abc transporter atp-binding protein
NHY62_08350	COG1522	sequence-specific DNA binding
NHY62_08365	COG1309	transcriptional regulator
NHY62_08405	COG0697	spore germination
NHY62_08430	COG3121	Chaperone
NHY62_08435	COG3539	Fimbrial protein
NHY62_08460	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NHY62_08460	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NHY62_08515	COG2353	YceI-like domain
NHY62_08525	COG3698	Phosphodiester glycosidase
NHY62_08540	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NHY62_08555	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NHY62_08560	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NHY62_08580	COG1132	(ABC) transporter
NHY62_08585	COG3122	Protein conserved in bacteria
NHY62_08590	COG3619	membrane
NHY62_08600	COG0640	Transcriptional regulator
NHY62_08610	COG2850	peptidyl-arginine hydroxylation
NHY62_08615	COG0424	maF-like protein
NHY62_08635	COG0191	fructose-bisphosphate aldolase activity
NHY62_08640	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NHY62_08655	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NHY62_08665	COG1192	Involved in chromosome partitioning
NHY62_08670	COG1475	DNA binding
NHY62_08675	COG0811	peptide transport
NHY62_08710	COG0084	hydrolase, TatD family'
NHY62_08775	COG0776	regulation of translation
NHY62_08805	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NHY62_08810	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NHY62_08860	COG0339	signal peptide processing
NHY62_08870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHY62_08905	COG0702	epimerase
NHY62_08910	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NHY62_08960	COG0316	Belongs to the HesB IscA family
NHY62_08965	COG0822	iron-sulfur transferase activity
NHY62_08990	COG0776	regulation of translation
NHY62_08995	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NHY62_09005	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NHY62_09010	COG1960	acyl-CoA dehydrogenase activity
NHY62_09050	COG4264	IucA IucC family
NHY62_09055	COG4264	IucA IucC family
NHY62_09095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NHY62_09110	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NHY62_09160	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NHY62_09175	COG1131	(ABC) transporter
NHY62_09180	COG0842	Transport permease protein
NHY62_09185	COG0842	Transport permease protein
NHY62_09240	COG2226	methyltransferase
NHY62_09265	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NHY62_09300	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NHY62_09310	COG0133	tryptophan synthase activity
NHY62_09325	COG3706	GGDEF domain
NHY62_09340	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NHY62_09345	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NHY62_09350	COG0022	dehydrogenase e1 component
NHY62_09355	COG0508	dehydrogenase complex catalyzes the overall conversion of
NHY62_09370	COG1063	alcohol dehydrogenase
NHY62_09385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NHY62_09385	COG3453	Protein conserved in bacteria
NHY62_09400	COG0730	response to heat
NHY62_09415	COG2207	Transcriptional regulator
NHY62_09415	COG3708	Transcriptional regulator
NHY62_09420	COG1733	regulation of RNA biosynthetic process
NHY62_09425	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NHY62_09435	COG2188	Transcriptional regulator
NHY62_09450	COG4521	taurine ABC transporter
NHY62_09455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NHY62_09475	COG0477	Major facilitator Superfamily
NHY62_09485	COG1027	Aspartate ammonia-lyase
NHY62_09500	COG0583	DNA-binding transcription factor activity
NHY62_09505	COG0583	DNA-binding transcription factor activity
NHY62_09510	COG0183	Belongs to the thiolase family
NHY62_09515	COG2031	fatty acid transporter
NHY62_09520	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NHY62_09530	COG0583	DNA-binding transcription factor activity
NHY62_09540	COG2610	gluconate transmembrane transporter activity
NHY62_09545	COG1028	Short-chain dehydrogenase reductase Sdr
NHY62_09555	COG2207	Transcriptional regulator
NHY62_09570	COG1028	Short-chain dehydrogenase reductase Sdr
NHY62_09595	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NHY62_09595	COG0543	2 iron, 2 sulfur cluster binding
NHY62_09600	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
NHY62_09605	COG4638	Rieske (2fe-2S)
NHY62_09615	COG0725	ABC transporter, periplasmic molybdate-binding protein
NHY62_09620	COG4149	molybdate abc transporter
NHY62_09625	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NHY62_09630	COG1028	Short-chain dehydrogenase reductase Sdr
NHY62_09635	COG1535	isochorismatase
NHY62_09635	COG3433	isochorismatase activity
NHY62_09700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHY62_09715	COG0753	catalase activity
NHY62_09725	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
NHY62_09755	COG3539	Fimbrial protein
NHY62_09775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NHY62_09795	COG2072	flavoprotein involved in K transport
NHY62_09805	COG1538	Outer membrane efflux protein
NHY62_09815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NHY62_09825	COG2205	protein histidine kinase activity
NHY62_09835	COG2207	Transcriptional regulator
NHY62_09850	COG1028	Short-chain dehydrogenase reductase Sdr
NHY62_09900	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NHY62_10050	COG0659	secondary active sulfate transmembrane transporter activity
NHY62_10065	COG0129	dihydroxy-acid dehydratase activity
NHY62_10070	COG1012	belongs to the aldehyde dehydrogenase family
NHY62_10075	COG1012	belongs to the aldehyde dehydrogenase family
NHY62_10090	COG1566	PFAM secretion protein HlyD family protein
NHY62_10125	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NHY62_10155	COG0583	DNA-binding transcription factor activity
NHY62_10170	COG2188	Transcriptional regulator
NHY62_10200	COG3210	domain, Protein
NHY62_10205	COG2831	hemolysin activation secretion protein
NHY62_10215	COG1473	amidohydrolase
NHY62_10235	COG0583	DNA-binding transcription factor activity
NHY62_10240	COG1335	isochorismatase
NHY62_10250	COG1309	transcriptional regulator
NHY62_10290	COG0446	pyridine nucleotide-disulphide oxidoreductase
NHY62_10290	COG1902	pentaerythritol trinitrate reductase activity
NHY62_10295	COG1846	Transcriptional regulator
NHY62_10315	COG0753	catalase activity
NHY62_10330	COG1012	belongs to the aldehyde dehydrogenase family
NHY62_10355	COG3829	transcription factor binding
NHY62_10365	COG1960	acyl-CoA dehydrogenase activity
NHY62_10385	COG1012	belongs to the aldehyde dehydrogenase family
NHY62_10405	COG2186	Transcriptional regulator
NHY62_10420	COG4948	Mandelate Racemase Muconate Lactonizing
NHY62_10425	COG4829	muconolactone delta-isomerase
NHY62_10435	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NHY62_10440	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NHY62_10445	COG0183	Belongs to the thiolase family
NHY62_10450	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NHY62_10460	COG1012	belongs to the aldehyde dehydrogenase family
NHY62_10470	COG3733	amine oxidase
NHY62_10490	COG1028	Short-chain dehydrogenase reductase Sdr
NHY62_10500	COG4638	Rieske (2fe-2S)
NHY62_10520	COG0154	amidase activity
NHY62_10530	COG2814	Major facilitator Superfamily
NHY62_10555	COG1960	acyl-CoA dehydrogenase activity
NHY62_10560	COG0583	DNA-binding transcription factor activity
NHY62_10565	COG1414	Transcriptional regulator
NHY62_10580	COG2391	methyltransferase activity
NHY62_10595	COG3659	wide pore channel activity
NHY62_10600	COG3420	alginic acid biosynthetic process
NHY62_10605	COG0710	3-dehydroquinate dehydratase activity
NHY62_10610	COG3485	protocatechuate 3,4-dioxygenase
NHY62_10615	COG3485	protocatechuate 3,4-dioxygenase
NHY62_10620	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NHY62_10625	COG2271	Major facilitator Superfamily
NHY62_10630	COG0596	Alpha beta hydrolase
NHY62_10640	COG0183	Belongs to the thiolase family
NHY62_10645	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NHY62_10650	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NHY62_10665	COG2323	membrane
NHY62_10710	COG0446	pyridine nucleotide-disulphide oxidoreductase
NHY62_10710	COG1902	pentaerythritol trinitrate reductase activity
NHY62_10735	COG0542	response to heat
NHY62_10740	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NHY62_10795	COG4774	siderophore transport
NHY62_10800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NHY62_10830	COG4890	Cyd operon protein YbgT
NHY62_10845	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
NHY62_10855	COG0552	protein localization to endoplasmic reticulum
NHY62_10880	COG0517	IMP dehydrogenase activity
NHY62_10880	COG0516	GMP reductase activity
NHY62_10885	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NHY62_10890	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NHY62_10900	COG0583	DNA-binding transcription factor activity
NHY62_10905	COG0024	Methionine aminopeptidase
NHY62_10935	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NHY62_10935	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NHY62_10940	COG1105	Belongs to the carbohydrate kinase PfkB family
NHY62_10945	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
NHY62_10945	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NHY62_10945	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NHY62_10965	COG3300	MHYT domain
NHY62_10965	COG5001	Diguanylate cyclase
NHY62_10980	COG2135	peptidase activity
NHY62_11005	COG1113	amino acid transport
NHY62_11015	COG1522	sequence-specific DNA binding
NHY62_11040	COG1011	Hydrolase
NHY62_11045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NHY62_11055	COG2137	regulation of response to DNA damage stimulus
NHY62_11070	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NHY62_11105	COG0575	Belongs to the CDS family
NHY62_11110	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NHY62_11140	COG2204	response regulator
NHY62_11215	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
NHY62_11235	COG0697	spore germination
NHY62_11255	COG0521	Mo-molybdopterin cofactor biosynthetic process
NHY62_11255	COG0315	cyclic pyranopterin monophosphate synthase activity
NHY62_11270	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NHY62_11275	COG0243	molybdopterin cofactor binding
NHY62_11295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NHY62_11295	COG2146	nitrite reductase [NAD(P)H] activity
NHY62_11305	COG0745	RESPONSE REGULATOR receiver
NHY62_11310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NHY62_11310	COG1116	anion transmembrane transporter activity
NHY62_11330	COG0511	ligase activity, forming carbon-carbon bonds
NHY62_11345	COG2814	Major facilitator Superfamily
NHY62_11550	COG5410	chromosome segregation
NHY62_11790	COG1598	PFAM Uncharacterised protein family UPF0150
NHY62_12110	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NHY62_12125	COG0824	Thioesterase
NHY62_12135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHY62_12150	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NHY62_12155	COG2030	dehydratase
NHY62_12165	COG0183	Belongs to the thiolase family
NHY62_12175	COG0583	DNA-binding transcription factor activity
NHY62_12180	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NHY62_12190	COG1522	sequence-specific DNA binding
NHY62_12205	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NHY62_12230	COG0589	response to stress
NHY62_12235	COG0488	(ABC) transporter
NHY62_12290	COG0668	transmembrane transport
NHY62_12300	COG1309	transcriptional regulator
NHY62_12320	COG1605	Chorismate mutase
NHY62_12340	COG0308	aminopeptidase N
NHY62_12360	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
NHY62_12395	COG0531	amino acid
NHY62_12400	COG4303	Ethanolamine ammonia lyase large subunit
NHY62_12410	COG0519	Catalyzes the synthesis of GMP from XMP
NHY62_12410	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NHY62_12440	COG0697	spore germination
NHY62_12445	COG1923	regulation of RNA biosynthetic process
NHY62_12460	COG0802	atpase or kinase
NHY62_12480	COG1187	pseudouridine synthase activity
NHY62_12495	COG0583	DNA-binding transcription factor activity
NHY62_12510	COG2814	Major facilitator Superfamily
NHY62_12515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NHY62_12540	COG0729	surface antigen
NHY62_12560	COG0174	glutamine synthetase
NHY62_12565	COG0745	RESPONSE REGULATOR receiver
NHY62_12570	COG2205	protein histidine kinase activity
NHY62_12580	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NHY62_12585	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NHY62_12610	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NHY62_12615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NHY62_12620	COG1960	acyl-CoA dehydrogenase activity
NHY62_12640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NHY62_12660	COG0583	DNA-binding transcription factor activity
NHY62_12685	COG3658	cytochrome
NHY62_12690	COG1215	transferase activity, transferring glycosyl groups
NHY62_12720	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NHY62_12725	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NHY62_12735	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NHY62_12760	COG0305	Participates in initiation and elongation during chromosome replication
NHY62_12765	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NHY62_12775	COG1305	Transglutaminase-like
NHY62_12815	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NHY62_12820	COG0138	bifunctional purine biosynthesis protein purh
NHY62_12825	COG0151	Belongs to the GarS family
NHY62_12830	COG1464	Belongs to the NlpA lipoprotein family
NHY62_12835	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NHY62_12845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NHY62_12855	COG1301	dicarboxylic acid transport
NHY62_12910	COG0488	(ABC) transporter
NHY62_13060	COG2186	Transcriptional regulator
NHY62_13070	COG0786	glutamate:sodium symporter activity
NHY62_13075	COG3243	poly(R)-hydroxyalkanoic acid synthase
NHY62_13100	COG3111	PFAM Bacterial OB fold (BOF) protein
NHY62_13200	COG1610	YqeY-like protein
NHY62_13205	COG4783	chaperone-mediated protein folding
NHY62_13230	COG1286	toxin biosynthetic process
NHY62_13270	COG0513	Belongs to the DEAD box helicase family
NHY62_13325	COG1234	tRNA 3'-trailer cleavage
NHY62_13350	COG2819	hydrolase of the alpha beta superfamily
NHY62_13360	COG1301	dicarboxylic acid transport
NHY62_13370	COG3139	Protein of unknown function (DUF1315)
NHY62_13375	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NHY62_13390	COG0494	nUDIX hydrolase
NHY62_13400	COG0642	Histidine kinase
NHY62_13425	COG1720	tRNA m6t6A37 methyltransferase activity
NHY62_13440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NHY62_13445	COG0826	peptidase U32
NHY62_13450	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NHY62_13460	COG4598	ABC transporter
NHY62_13465	COG4160	amino acid transport
NHY62_13530	COG1131	(ABC) transporter
NHY62_13535	COG0842	Transport permease protein
NHY62_13550	COG0772	Belongs to the SEDS family
NHY62_13555	COG2951	lytic endotransglycosylase activity
NHY62_13595	COG0052	Belongs to the universal ribosomal protein uS2 family
NHY62_13600	COG0024	Methionine aminopeptidase
NHY62_13610	COG2223	nitrite transmembrane transporter activity
NHY62_13625	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NHY62_13630	COG1960	acyl-CoA dehydrogenase activity
NHY62_13650	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NHY62_13655	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NHY62_13680	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NHY62_13685	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NHY62_13720	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NHY62_13730	COG0174	glutamine synthetase
NHY62_14075	COG0512	Glutamine amidotransferase of anthranilate synthase
NHY62_14120	COG0302	gtp cyclohydrolase
NHY62_14145	COG3739	integral membrane protein
NHY62_14160	COG1169	isochorismate synthase
NHY62_14170	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
NHY62_14175	COG1132	(ABC) transporter
NHY62_14195	COG3433	isochorismatase activity
NHY62_14195	COG1535	isochorismatase
NHY62_14200	COG1021	2,3-dihydroxybenzoate-AMP ligase
NHY62_14205	COG1021	2,3-dihydroxybenzoate-AMP ligase
NHY62_14220	COG4774	siderophore transport
NHY62_14225	COG4607	ABC-type enterochelin transport system periplasmic component
NHY62_14230	COG4604	ABC transporter, ATP-binding protein
NHY62_14235	COG4605	iron ion homeostasis
NHY62_14240	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHY62_14260	COG2964	Protein conserved in bacteria
NHY62_14270	COG1741	Belongs to the pirin family
NHY62_14290	COG1309	transcriptional regulator
NHY62_14300	COG4948	Mandelate Racemase Muconate Lactonizing
NHY62_14305	COG2814	Major facilitator Superfamily
NHY62_14355	COG2879	small protein
NHY62_14405	COG1067	ATP-dependent peptidase activity
NHY62_14410	COG0583	DNA-binding transcription factor activity
NHY62_14440	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NHY62_14475	COG0616	signal peptide processing
NHY62_14490	COG0573	inorganic phosphate transmembrane transporter activity
NHY62_14495	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NHY62_14500	COG1113	amino acid transport
NHY62_14505	COG3961	Belongs to the TPP enzyme family
NHY62_14510	COG1522	sequence-specific DNA binding
NHY62_14535	COG1309	transcriptional regulator
NHY62_14550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NHY62_14585	COG0352	thiamine-phosphate diphosphorylase activity
NHY62_14620	COG1823	symporter activity
NHY62_14625	COG0583	DNA-binding transcription factor activity
NHY62_14630	COG0477	Major facilitator Superfamily
NHY62_14675	COG1252	NADH dehydrogenase
NHY62_14700	COG1215	transferase activity, transferring glycosyl groups
NHY62_14730	COG2070	2-Nitropropane dioxygenase
NHY62_14835	COG4221	oxidoreductase activity
NHY62_14845	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NHY62_14850	COG1381	Involved in DNA repair and RecF pathway recombination
NHY62_14860	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NHY62_14875	COG0681	Belongs to the peptidase S26 family
NHY62_14890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NHY62_14910	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NHY62_14915	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NHY62_14920	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NHY62_14930	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NHY62_14935	COG4208	sulfate ABC transporter
NHY62_14945	COG0583	DNA-binding transcription factor activity
NHY62_14950	COG4625	pathogenesis
NHY62_14965	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NHY62_14980	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NHY62_14990	COG1056	cytidyltransferase-related domain
NHY62_14990	COG1051	belongs to the nudix hydrolase family
NHY62_15010	COG2814	Major facilitator Superfamily
NHY62_15035	COG1473	amidohydrolase
NHY62_15040	COG0824	Thioesterase
NHY62_15060	COG0823	Involved in the tonB-independent uptake of proteins
NHY62_15125	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NHY62_15130	COG0596	Alpha beta hydrolase
NHY62_15135	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NHY62_15135	COG0616	signal peptide processing
NHY62_15145	COG2333	competence protein COMEC
NHY62_15145	COG0658	competence protein
NHY62_15150	COG1136	(ABC) transporter
NHY62_15220	COG0463	Glycosyl transferase, family 2
NHY62_15250	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NHY62_15255	COG1280	lysine exporter protein (LysE YggA)
NHY62_15265	COG0019	diaminopimelate decarboxylase activity
NHY62_15275	COG1113	amino acid transport
NHY62_15300	COG3339	Conserved Protein
NHY62_15305	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NHY62_15310	COG0243	molybdopterin cofactor binding
NHY62_15315	COG1929	Belongs to the glycerate kinase type-1 family
NHY62_15330	COG0778	Nitroreductase
NHY62_15360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NHY62_15375	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NHY62_15395	COG0741	lytic transglycosylase activity
NHY62_15415	COG0584	glycerophosphoryl diester phosphodiesterase
NHY62_15420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NHY62_15445	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NHY62_15450	COG1597	lipid kinase activity
NHY62_15470	COG0477	Major facilitator Superfamily
NHY62_15520	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NHY62_15525	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NHY62_15550	COG0505	Belongs to the CarA family
NHY62_15570	COG0589	response to stress
NHY62_15585	COG2843	Capsule synthesis protein
NHY62_15630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NHY62_15655	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NHY62_15665	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NHY62_15670	COG2009	succinate dehydrogenase
NHY62_15710	COG2921	Belongs to the UPF0250 family
NHY62_15715	COG0321	lipoyl(octanoyl) transferase activity
NHY62_15730	COG0531	amino acid
NHY62_15740	COG1733	regulation of RNA biosynthetic process
NHY62_15745	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NHY62_15750	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NHY62_15750	COG1648	precorrin-2 dehydrogenase activity
NHY62_15765	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NHY62_15795	COG0671	phosphoesterase, PA-phosphatase related
NHY62_15800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NHY62_15810	COG1538	Outer membrane efflux protein
NHY62_15815	COG0393	Putative heavy-metal-binding
NHY62_15820	COG0393	Putative heavy-metal-binding
NHY62_15830	COG1028	Short-chain dehydrogenase reductase Sdr
NHY62_15860	COG0583	DNA-binding transcription factor activity
NHY62_15865	COG0004	ammonium transporteR
NHY62_15880	COG0745	RESPONSE REGULATOR receiver
NHY62_15885	COG2194	sulfuric ester hydrolase activity
NHY62_15905	COG1752	Esterase of the alpha-beta hydrolase superfamily
NHY62_15920	COG2315	Protein conserved in bacteria
NHY62_15925	COG0142	geranyltranstransferase activity
NHY62_15930	COG2828	Protein conserved in bacteria
NHY62_15935	COG1113	amino acid transport
NHY62_15955	COG2207	Transcriptional regulator
NHY62_15980	COG2249	NAD(P)H dehydrogenase (quinone) activity
NHY62_15990	COG0560	Phosphoserine phosphatase
NHY62_16010	COG1530	ribonuclease E activity
NHY62_16015	COG0424	maF-like protein
NHY62_16020	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NHY62_16025	COG1792	Involved in formation and maintenance of cell shape
NHY62_16030	COG1077	Cell shape determining protein MreB Mrl
NHY62_16035	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHY62_16045	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHY62_16075	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
NHY62_16080	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NHY62_16090	COG1115	amino acid carrier protein
NHY62_16115	COG1289	transmembrane transporter activity
NHY62_16125	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NHY62_16165	COG1376	ErfK ybiS ycfS ynhG family protein
NHY62_16170	COG2832	Protein of unknown function (DUF454)
NHY62_16180	COG5510	response to toxic substance
NHY62_16245	COG2824	Alkylphosphonate utilization operon protein PhnA
NHY62_16250	COG3189	MarR family transcriptional regulator
NHY62_16260	COG0354	folic acid binding
NHY62_16265	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NHY62_16280	COG1902	pentaerythritol trinitrate reductase activity
NHY62_16325	COG1217	gtp-binding protein TYPA
NHY62_16345	COG1690	Belongs to the RtcB family
NHY62_16355	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NHY62_16355	COG2885	chlorophyll binding
NHY62_16405	COG2207	Transcriptional regulator
NHY62_16410	COG0183	Belongs to the thiolase family
NHY62_16445	COG0477	Major facilitator Superfamily
NHY62_16460	COG0450	alkyl hydroperoxide reductase
NHY62_16480	COG0285	dihydrofolate synthase activity
NHY62_16530	COG2096	Adenosyltransferase
NHY62_16550	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NHY62_16555	COG0745	RESPONSE REGULATOR receiver
NHY62_16560	COG2205	protein histidine kinase activity
NHY62_16575	COG1960	acyl-CoA dehydrogenase activity
NHY62_16580	COG0583	DNA-binding transcription factor activity
NHY62_16585	COG0625	glutathione transferase activity
NHY62_16650	COG0438	transferase activity, transferring glycosyl groups
NHY62_16655	COG0463	Glycosyl transferase, family 2
NHY62_16660	COG0726	polysaccharide deacetylase
NHY62_16680	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NHY62_16735	COG1862	Preprotein translocase
NHY62_16750	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NHY62_16765	COG0613	PHP domain protein
NHY62_16775	COG2350	Protein conserved in bacteria
NHY62_16805	COG1607	acyl-coa hydrolase
NHY62_16870	COG2199	diguanylate cyclase activity
NHY62_16880	COG1408	metallophosphoesterase
NHY62_16885	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHY62_16895	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NHY62_16915	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NHY62_16920	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NHY62_16935	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NHY62_16945	COG2969	positive regulation of protein catabolic process
NHY62_16965	COG1960	acyl-CoA dehydrogenase activity
NHY62_16970	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NHY62_16990	COG1960	acyl-CoA dehydrogenase activity
NHY62_17035	COG1183	phosphatidylcholine synthase activity
NHY62_17070	COG0741	lytic transglycosylase activity
NHY62_17070	COG0739	heme binding
NHY62_17070	COG1196	nuclear chromosome segregation
NHY62_17080	COG1702	phosphate starvation-inducible protein PhoH
NHY62_17115	COG1295	ribonuclease BN
NHY62_17120	COG0697	spore germination
NHY62_17125	COG2169	Transcriptional regulator
NHY62_17130	COG0179	Fumarylacetoacetate (FAA) hydrolase
NHY62_17180	COG0339	signal peptide processing
NHY62_17185	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
NHY62_17215	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
NHY62_17220	COG1960	acyl-CoA dehydrogenase activity
NHY62_17375	COG0626	cystathionine gamma-synthase activity
NHY62_17380	COG0433	COG0433 Predicted ATPase
NHY62_17390	COG1959	2 iron, 2 sulfur cluster binding
NHY62_17410	COG1946	Acyl-CoA thioesterase
NHY62_17430	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NHY62_17435	COG1040	competence protein
NHY62_17440	COG0494	nUDIX hydrolase
NHY62_17450	COG0598	Magnesium transport protein CorA
NHY62_17460	COG2854	intermembrane phospholipid transfer
NHY62_17470	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NHY62_17475	COG1127	ABC transporter
NHY62_17485	COG0513	Belongs to the DEAD box helicase family
NHY62_17505	COG0408	coproporphyrinogen oxidase activity
NHY62_17520	COG1960	acyl-CoA dehydrogenase activity
NHY62_17530	COG1983	PspC domain protein
NHY62_17535	COG0517	IMP dehydrogenase activity
NHY62_17580	COG0583	DNA-binding transcription factor activity
NHY62_17620	COG1012	belongs to the aldehyde dehydrogenase family
NHY62_17630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NHY62_17635	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NHY62_17670	COG1192	Involved in chromosome partitioning
NHY62_17675	COG0628	permease
NHY62_17705	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NHY62_17715	COG0277	FAD linked oxidase domain protein
NHY62_17720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NHY62_17745	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NHY62_17750	COG5380	lipid catabolic process
NHY62_17770	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NHY62_17820	COG0194	GDP metabolic process
NHY62_17890	COG0493	'glutamate synthase
NHY62_17945	COG2226	methyltransferase
NHY62_17965	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NHY62_18010	COG0833	amino acid
NHY62_18095	COG0488	(ABC) transporter
NHY62_18105	COG4221	oxidoreductase activity
NHY62_18135	COG0427	acetyl-CoA hydrolase
NHY62_18165	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NHY62_18195	COG2329	Antibiotic biosynthesis monooxygenase
NHY62_18210	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NHY62_18275	COG2249	NAD(P)H dehydrogenase (quinone) activity
NHY62_18280	COG1733	regulation of RNA biosynthetic process
NHY62_18315	COG0667	Aldo Keto reductase
NHY62_18335	COG0583	DNA-binding transcription factor activity
NHY62_18340	COG2814	Major facilitator Superfamily
NHY62_18385	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NHY62_18405	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NHY62_18430	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NHY62_18430	COG0352	thiamine-phosphate diphosphorylase activity
NHY62_18430	COG0351	phosphomethylpyrimidine kinase
NHY62_18455	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NHY62_18475	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NHY62_18485	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NHY62_18520	COG3328	transposase activity
NHY62_18525	COG1522	sequence-specific DNA binding
NHY62_18530	COG1335	isochorismatase
NHY62_18550	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NHY62_18555	COG1519	Transferase
NHY62_18560	COG1902	pentaerythritol trinitrate reductase activity
NHY62_18580	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NHY62_18605	COG0426	domain, Protein
NHY62_18605	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NHY62_18625	COG2119	membrane
NHY62_18645	COG4942	peptidase
NHY62_18670	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NHY62_18690	COG0189	ligase activity
NHY62_18710	COG0708	Exodeoxyribonuclease III
NHY62_18715	COG1393	Belongs to the ArsC family
NHY62_18730	COG3706	GGDEF domain
NHY62_18765	COG2351	hydroxyisourate hydrolase activity
NHY62_18770	COG2233	PERMEase
NHY62_18775	COG2233	PERMEase
NHY62_18785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NHY62_18795	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
NHY62_18800	COG1028	Short-chain dehydrogenase reductase Sdr
NHY62_18810	COG3150	esterase
NHY62_18845	COG2918	glutathione biosynthetic process
NHY62_18860	COG2733	membrane
NHY62_18865	COG0436	Aminotransferase
NHY62_18870	COG0534	Mate efflux family protein
NHY62_18970	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NHY62_19005	COG0010	Belongs to the arginase family
NHY62_19045	COG0523	cobalamin synthesis protein
NHY62_19055	COG1113	amino acid transport
NHY62_19065	COG0625	glutathione transferase activity
NHY62_19085	COG1683	Conserved Protein
NHY62_19095	COG0385	Bile acid
NHY62_19100	COG1335	isochorismatase
NHY62_19105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NHY62_19125	COG2116	formate transmembrane transporter activity
NHY62_19130	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NHY62_19135	COG2133	pyrroloquinoline quinone binding
NHY62_19140	COG2983	Belongs to the UPF0260 family
NHY62_19160	COG1194	a g-specific adenine glycosylase
NHY62_19175	COG2818	Glycosylase
NHY62_19185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NHY62_19200	COG0583	DNA-binding transcription factor activity
NHY62_19205	COG0656	L-ascorbic acid biosynthetic process
NHY62_19260	COG2233	PERMEase
NHY62_19300	COG0733	neurotransmitter:sodium symporter activity
NHY62_19340	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NHY62_19350	COG0596	Alpha beta hydrolase
NHY62_19385	COG0586	Pfam SNARE associated Golgi protein
NHY62_19430	COG0706	membrane insertase activity
NHY62_19445	COG1230	cation diffusion facilitator family transporter
NHY62_19450	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NHY62_19475	COG0754	glutathionylspermidine amidase activity
NHY62_19485	COG0861	Integral membrane protein TerC family
NHY62_19490	COG0671	phosphoesterase, PA-phosphatase related
NHY62_19500	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NHY62_19515	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NHY62_19520	COG2951	lytic endotransglycosylase activity
NHY62_19665	COG0741	lytic transglycosylase activity
NHY62_19700	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NHY62_19875	COG1525	nuclease
NHY62_19940	COG1475	DNA binding
NHY62_19960	COG3853	Toxic anion resistance protein (TelA)