locus-tag	class	description
NHY65_00005	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHY65_00035	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NHY65_00045	COG0351	phosphomethylpyrimidine kinase
NHY65_00045	COG0352	thiamine-phosphate diphosphorylase activity
NHY65_00045	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NHY65_00050	COG1652	LysM domain
NHY65_00075	COG1399	metal-binding, possibly nucleic acid-binding protein
NHY65_00080	COG3101	peptidyl-lysine hydroxylation
NHY65_00085	COG0009	L-threonylcarbamoyladenylate synthase
NHY65_00090	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NHY65_00095	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NHY65_00110	COG4106	trans-aconitate 2-methyltransferase activity
NHY65_00125	COG2226	methyltransferase
NHY65_00125	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NHY65_00125	COG0596	Alpha beta hydrolase
NHY65_00130	COG1877	trehalose-phosphatase activity
NHY65_00135	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
NHY65_00140	COG2223	nitrite transmembrane transporter activity
NHY65_00170	COG0730	response to heat
NHY65_00185	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NHY65_00195	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NHY65_00245	COG0489	protein tyrosine kinase activity
NHY65_00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NHY65_00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NHY65_00285	COG2515	1-aminocyclopropane-1-carboxylate deaminase
NHY65_00300	COG0668	transmembrane transport
NHY65_00320	COG0583	DNA-binding transcription factor activity
NHY65_00340	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NHY65_00345	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NHY65_00375	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NHY65_00435	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHY65_00445	COG2205	protein histidine kinase activity
NHY65_00540	COG0384	phenazine biosynthesis protein PhzF
NHY65_00610	COG0583	DNA-binding transcription factor activity
NHY65_00625	COG0583	DNA-binding transcription factor activity
NHY65_00630	COG1053	succinate dehydrogenase
NHY65_00640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NHY65_00645	COG2814	Major facilitator Superfamily
NHY65_00650	COG1960	acyl-CoA dehydrogenase activity
NHY65_00655	COG0583	DNA-binding transcription factor activity
NHY65_00660	COG1063	alcohol dehydrogenase
NHY65_00690	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NHY65_00695	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NHY65_00700	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NHY65_00720	COG2132	Multicopper oxidase
NHY65_00730	COG0561	phosphatase activity
NHY65_00735	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NHY65_00760	COG1214	PFAM Peptidase M22, glycoprotease
NHY65_00810	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NHY65_00820	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NHY65_00825	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NHY65_00830	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHY65_00890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NHY65_00905	COG1764	response to oxidative stress
NHY65_00955	COG0248	Ppx GppA phosphatase
NHY65_00985	COG0072	phenylalanine-tRNA ligase activity
NHY65_01030	COG1238	metal cluster binding
NHY65_01035	COG0625	glutathione transferase activity
NHY65_01050	COG0318	PFAM AMP-dependent synthetase and ligase
NHY65_01055	COG3028	Belongs to the UPF0307 family
NHY65_01060	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NHY65_01080	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NHY65_01090	COG1555	photosystem II stabilization
NHY65_01130	COG1024	Enoyl-CoA hydratase
NHY65_01135	COG2084	Dehydrogenase
NHY65_01140	COG3622	Belongs to the hyi family
NHY65_01170	COG0697	spore germination
NHY65_01180	COG2814	Major facilitator Superfamily
NHY65_01195	COG0583	DNA-binding transcription factor activity
NHY65_01220	COG0084	hydrolase, TatD family'
NHY65_01235	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NHY65_01265	COG0440	acetolactate synthase activity
NHY65_01270	COG0028	Belongs to the TPP enzyme family
NHY65_01295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NHY65_01305	COG1538	Outer membrane efflux protein
NHY65_01320	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NHY65_01325	COG1162	GTPase activity
NHY65_01335	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NHY65_01355	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NHY65_01360	COG1028	Short-chain dehydrogenase reductase Sdr
NHY65_01415	COG0318	PFAM AMP-dependent synthetase and ligase
NHY65_01425	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHY65_01470	COG1426	Protein conserved in bacteria
NHY65_01505	COG0793	Belongs to the peptidase S41A family
NHY65_01520	COG2267	carboxylic ester hydrolase activity
NHY65_01530	COG1012	belongs to the aldehyde dehydrogenase family
NHY65_01535	COG3265	gluconokinase activity
NHY65_01545	COG0800	Aldolase
NHY65_01565	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
NHY65_01565	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
NHY65_01585	COG0740	serine-type endopeptidase activity
NHY65_01605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NHY65_01615	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NHY65_01615	COG2813	Specifically methylates the guanine in position
NHY65_01715	COG0788	formyltetrahydrofolate deformylase activity
NHY65_01760	COG0724	RNA recognition motif
NHY65_01765	COG0210	DNA helicase
NHY65_01790	COG1733	regulation of RNA biosynthetic process
NHY65_01800	COG2900	Belongs to the SlyX family
NHY65_01805	COG0488	(ABC) transporter
NHY65_01810	COG1280	lysine exporter protein (LysE YggA)
NHY65_01825	COG1301	dicarboxylic acid transport
NHY65_01880	COG0473	3-isopropylmalate dehydrogenase activity
NHY65_01945	COG0583	DNA-binding transcription factor activity
NHY65_01955	COG0625	glutathione transferase activity
NHY65_01960	COG2378	regulation of single-species biofilm formation
NHY65_01965	COG0546	phosphoglycolate phosphatase activity
NHY65_01975	COG1530	ribonuclease E activity
NHY65_01980	COG0318	PFAM AMP-dependent synthetase and ligase
NHY65_01995	COG0583	DNA-binding transcription factor activity
NHY65_02000	COG4221	oxidoreductase activity
NHY65_02005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NHY65_02015	COG0534	Mate efflux family protein
NHY65_02070	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
NHY65_02075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NHY65_02095	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NHY65_02105	COG0644	oxidoreductase
NHY65_02105	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
NHY65_02110	COG0425	Belongs to the sulfur carrier protein TusA family
NHY65_02125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NHY65_02155	COG0475	glutathione-regulated potassium exporter activity
NHY65_02155	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NHY65_02160	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NHY65_02170	COG0484	heat shock protein binding
NHY65_02175	COG0789	Transcriptional regulator
NHY65_02180	COG0598	Magnesium transport protein CorA
NHY65_02195	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NHY65_02200	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NHY65_02210	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NHY65_02230	COG2226	methyltransferase
NHY65_02245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NHY65_02250	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NHY65_02270	COG1006	Multisubunit Na H antiporter MnhC subunit
NHY65_02275	COG0651	ATP synthesis coupled electron transport
NHY65_02280	COG1863	multisubunit Na H antiporter MnhE subunit
NHY65_02285	COG2212	antiporter activity
NHY65_02290	COG1320	monovalent cation:proton antiporter activity
NHY65_02305	COG0195	Participates in both transcription termination and antitermination
NHY65_02355	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NHY65_02370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHY65_02395	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NHY65_02425	COG2169	Transcriptional regulator
NHY65_02425	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NHY65_02430	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NHY65_02495	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NHY65_02510	COG0326	Molecular chaperone. Has ATPase activity
NHY65_02625	COG0546	phosphoglycolate phosphatase activity
NHY65_02630	COG1716	ATPase activity
NHY65_02675	COG0181	hydroxymethylbilane synthase activity
NHY65_02705	COG1538	Outer membrane efflux protein
NHY65_02710	COG0697	spore germination
NHY65_02740	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NHY65_02745	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NHY65_02750	COG0772	Belongs to the SEDS family
NHY65_02790	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NHY65_02800	COG2197	response regulator
NHY65_02815	COG0793	Belongs to the peptidase S41A family
NHY65_02820	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NHY65_02825	COG0795	lipopolysaccharide-transporting ATPase activity
NHY65_02865	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NHY65_02865	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NHY65_02875	COG0004	ammonium transporteR
NHY65_02880	COG0347	Belongs to the P(II) protein family
NHY65_02955	COG1061	Type III restriction enzyme res subunit
NHY65_02960	COG1002	Type II restriction enzyme, methylase subunits
NHY65_02970	COG0659	secondary active sulfate transmembrane transporter activity
NHY65_02975	COG0589	response to stress
NHY65_03010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NHY65_03020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NHY65_03040	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NHY65_03070	COG2860	membrane
NHY65_03100	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHY65_03140	COG0655	NAD(P)H dehydrogenase (quinone) activity
NHY65_03150	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NHY65_03230	COG0697	spore germination
NHY65_03235	COG1309	transcriptional regulator
NHY65_03250	COG0386	Belongs to the glutathione peroxidase family
NHY65_03315	COG1121	(ABC) transporter
NHY65_03320	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NHY65_03325	COG1280	lysine exporter protein (LysE YggA)
NHY65_03330	COG2837	iron assimilation
NHY65_03340	COG0281	malic enzyme
NHY65_03385	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NHY65_03385	COG0519	Catalyzes the synthesis of GMP from XMP
NHY65_03390	COG4399	Belongs to the UPF0754 family
NHY65_03395	COG2259	Doxx family
NHY65_03400	COG0586	Pfam SNARE associated Golgi protein
NHY65_03415	COG1192	Involved in chromosome partitioning
NHY65_03425	COG0271	Belongs to the BolA IbaG family
NHY65_03445	COG2267	carboxylic ester hydrolase activity
NHY65_03465	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NHY65_03465	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHY65_03465	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NHY65_03465	COG3321	synthase
NHY65_03480	COG2197	response regulator
NHY65_03490	COG3916	Acyl-homoserine-lactone synthase
NHY65_03505	COG1024	Enoyl-CoA hydratase
NHY65_03510	COG1960	acyl-CoA dehydrogenase activity
NHY65_03515	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NHY65_03535	COG1113	amino acid transport
NHY65_03550	COG0251	oxidation-reduction process
NHY65_03590	COG0564	pseudouridine synthase activity
NHY65_03670	COG1802	Transcriptional regulator
NHY65_03680	COG1448	Aminotransferase
NHY65_03695	COG2186	Transcriptional regulator
NHY65_03705	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NHY65_03715	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NHY65_03730	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NHY65_03735	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NHY65_03755	COG0438	transferase activity, transferring glycosyl groups
NHY65_03760	COG1215	transferase activity, transferring glycosyl groups
NHY65_03770	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NHY65_03805	COG3023	N-Acetylmuramoyl-L-alanine amidase
NHY65_03870	COG1028	Short-chain dehydrogenase reductase Sdr
NHY65_03890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NHY65_03895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NHY65_03900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHY65_03905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NHY65_03910	COG1116	anion transmembrane transporter activity
NHY65_03915	COG1309	transcriptional regulator
NHY65_03920	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NHY65_03930	COG0196	riboflavin kinase activity
NHY65_03945	COG1047	Peptidyl-prolyl cis-trans
NHY65_03985	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NHY65_03990	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
NHY65_03995	COG0596	Alpha beta hydrolase
NHY65_04020	COG0488	(ABC) transporter
NHY65_04025	COG0586	Pfam SNARE associated Golgi protein
NHY65_04035	COG0187	DNA topoisomerase II activity
NHY65_04045	COG0592	DNA-directed DNA polymerase activity
NHY65_04090	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NHY65_04105	COG0402	S-adenosylhomocysteine deaminase activity
NHY65_04115	COG0754	glutathionylspermidine amidase activity
NHY65_04125	COG0861	Integral membrane protein TerC family
NHY65_04130	COG0671	phosphoesterase, PA-phosphatase related
NHY65_04140	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NHY65_04155	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NHY65_04190	COG0583	DNA-binding transcription factor activity
NHY65_04210	COG0657	acetylesterase activity
NHY65_04215	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NHY65_04255	COG0733	neurotransmitter:sodium symporter activity
NHY65_04290	COG0583	DNA-binding transcription factor activity
NHY65_04295	COG2233	PERMEase
NHY65_04310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NHY65_04350	COG0656	L-ascorbic acid biosynthetic process
NHY65_04355	COG0583	DNA-binding transcription factor activity
NHY65_04375	COG1064	alcohol dehydrogenase
NHY65_04380	COG2818	Glycosylase
NHY65_04395	COG1194	a g-specific adenine glycosylase
NHY65_04410	COG5487	UPF0391 membrane protein
NHY65_04415	COG2983	Belongs to the UPF0260 family
NHY65_04420	COG2133	pyrroloquinoline quinone binding
NHY65_04425	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NHY65_04430	COG2116	formate transmembrane transporter activity
NHY65_04450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NHY65_04455	COG1335	isochorismatase
NHY65_04460	COG0385	Bile acid
NHY65_04465	COG0534	Mate efflux family protein
NHY65_04470	COG1683	Conserved Protein
NHY65_04490	COG0625	glutathione transferase activity
NHY65_04510	COG0523	cobalamin synthesis protein
NHY65_04520	COG2188	Transcriptional regulator
NHY65_04550	COG0010	Belongs to the arginase family
NHY65_04565	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NHY65_04570	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NHY65_04580	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NHY65_04585	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NHY65_04685	COG0534	Mate efflux family protein
NHY65_04690	COG0436	Aminotransferase
NHY65_04695	COG2733	membrane
NHY65_04710	COG2918	glutathione biosynthetic process
NHY65_04740	COG3150	esterase
NHY65_04750	COG1028	Short-chain dehydrogenase reductase Sdr
NHY65_04755	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
NHY65_04765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NHY65_04775	COG2233	PERMEase
NHY65_04780	COG2351	hydroxyisourate hydrolase activity
NHY65_04815	COG3706	GGDEF domain
NHY65_04855	COG0189	ligase activity
NHY65_04875	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NHY65_04885	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NHY65_04900	COG4942	peptidase
NHY65_04910	COG0508	dehydrogenase complex catalyzes the overall conversion of
NHY65_04920	COG2119	membrane
NHY65_04940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NHY65_04940	COG0426	domain, Protein
NHY65_04965	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NHY65_04985	COG1902	pentaerythritol trinitrate reductase activity
NHY65_04990	COG1519	Transferase
NHY65_04995	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NHY65_05000	COG0668	transmembrane transport
NHY65_05015	COG1335	isochorismatase
NHY65_05020	COG1522	sequence-specific DNA binding
NHY65_05050	COG2198	Histidine kinase
NHY65_05050	COG2205	protein histidine kinase activity
NHY65_05050	COG0784	Response regulator, receiver
NHY65_05055	COG3162	membrane
NHY65_05060	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NHY65_05070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NHY65_05095	COG1765	OsmC-like protein
NHY65_05115	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NHY65_05120	COG1309	transcriptional regulator
NHY65_05140	COG0351	phosphomethylpyrimidine kinase
NHY65_05140	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NHY65_05140	COG0352	thiamine-phosphate diphosphorylase activity
NHY65_05150	COG2814	Major facilitator Superfamily
NHY65_05160	COG4974	Belongs to the 'phage' integrase family
NHY65_05235	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NHY65_05245	COG1113	amino acid transport
NHY65_05255	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NHY65_05260	COG1012	belongs to the aldehyde dehydrogenase family
NHY65_05270	COG1335	isochorismatase
NHY65_05300	COG2814	Major facilitator Superfamily
NHY65_05360	COG1733	regulation of RNA biosynthetic process
NHY65_05365	COG2249	NAD(P)H dehydrogenase (quinone) activity
NHY65_05430	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NHY65_05475	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NHY65_05505	COG0427	acetyl-CoA hydrolase
NHY65_05530	COG0659	secondary active sulfate transmembrane transporter activity
NHY65_05535	COG4221	oxidoreductase activity
NHY65_05545	COG0488	(ABC) transporter
NHY65_05630	COG0833	amino acid
NHY65_05675	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NHY65_05680	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NHY65_05695	COG2226	methyltransferase
NHY65_05750	COG0493	'glutamate synthase
NHY65_05765	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
NHY65_05785	COG3307	-O-antigen
NHY65_05805	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NHY65_05820	COG0194	GDP metabolic process
NHY65_05870	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NHY65_05895	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NHY65_05920	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NHY65_05935	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NHY65_05940	COG2249	NAD(P)H dehydrogenase (quinone) activity
NHY65_05965	COG0628	permease
NHY65_05970	COG1192	Involved in chromosome partitioning
NHY65_06000	COG0833	amino acid
NHY65_06005	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NHY65_06010	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NHY65_06020	COG1012	belongs to the aldehyde dehydrogenase family
NHY65_06060	COG0583	DNA-binding transcription factor activity
NHY65_06105	COG0517	IMP dehydrogenase activity
NHY65_06120	COG1960	acyl-CoA dehydrogenase activity
NHY65_06135	COG0408	coproporphyrinogen oxidase activity
NHY65_06155	COG0513	Belongs to the DEAD box helicase family
NHY65_06165	COG1127	ABC transporter
NHY65_06190	COG0598	Magnesium transport protein CorA
NHY65_06200	COG0494	nUDIX hydrolase
NHY65_06205	COG1040	competence protein
NHY65_06210	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NHY65_06230	COG1946	Acyl-CoA thioesterase
NHY65_06235	COG1301	dicarboxylic acid transport
NHY65_06250	COG1959	2 iron, 2 sulfur cluster binding
NHY65_06255	COG1017	nitric oxide dioxygenase activity
NHY65_06255	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NHY65_06260	COG0433	COG0433 Predicted ATPase
NHY65_06425	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
NHY65_06455	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
NHY65_06460	COG0339	signal peptide processing
NHY65_06465	COG0557	exoribonuclease II activity
NHY65_06510	COG0179	Fumarylacetoacetate (FAA) hydrolase
NHY65_06520	COG0697	spore germination
NHY65_06560	COG1702	phosphate starvation-inducible protein PhoH
NHY65_06600	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NHY65_06605	COG1183	phosphatidylcholine synthase activity
NHY65_06650	COG1960	acyl-CoA dehydrogenase activity
NHY65_06655	COG1309	transcriptional regulator
NHY65_06670	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NHY65_06675	COG1960	acyl-CoA dehydrogenase activity
NHY65_06695	COG2969	positive regulation of protein catabolic process
NHY65_06705	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NHY65_06745	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NHY65_06760	COG1408	metallophosphoesterase
NHY65_06770	COG2199	diguanylate cyclase activity
NHY65_06830	COG1607	acyl-coa hydrolase
NHY65_06860	COG2350	Protein conserved in bacteria
NHY65_06870	COG0613	PHP domain protein
NHY65_06875	COG3781	membrane
NHY65_06885	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NHY65_06890	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NHY65_06900	COG1862	Preprotein translocase
NHY65_06960	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NHY65_06980	COG0726	polysaccharide deacetylase
NHY65_06985	COG0463	Glycosyl transferase, family 2
NHY65_07055	COG0625	glutathione transferase activity
NHY65_07060	COG0583	DNA-binding transcription factor activity
NHY65_07070	COG1960	acyl-CoA dehydrogenase activity
NHY65_07080	COG2205	protein histidine kinase activity
NHY65_07085	COG0745	RESPONSE REGULATOR receiver
NHY65_07090	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NHY65_07110	COG2096	Adenosyltransferase
NHY65_07160	COG0285	dihydrofolate synthase activity
NHY65_07180	COG0450	alkyl hydroperoxide reductase
NHY65_07230	COG0183	Belongs to the thiolase family
NHY65_07235	COG2207	Transcriptional regulator
NHY65_07255	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NHY65_07275	COG0183	Belongs to the thiolase family
NHY65_07285	COG2885	chlorophyll binding
NHY65_07285	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NHY65_07295	COG1690	Belongs to the RtcB family
NHY65_07310	COG2233	PERMEase
NHY65_07340	COG2094	Belongs to the DNA glycosylase MPG family
NHY65_07360	COG1902	pentaerythritol trinitrate reductase activity
NHY65_07375	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NHY65_07380	COG0354	folic acid binding
NHY65_07390	COG3189	MarR family transcriptional regulator
NHY65_07395	COG2824	Alkylphosphonate utilization operon protein PhnA
NHY65_07400	COG3422	double-strand break repair
NHY65_07460	COG5510	response to toxic substance
NHY65_07470	COG2832	Protein of unknown function (DUF454)
NHY65_07475	COG1376	ErfK ybiS ycfS ynhG family protein
NHY65_07515	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NHY65_07525	COG1289	transmembrane transporter activity
NHY65_07555	COG1752	Esterase of the alpha-beta hydrolase superfamily
NHY65_07560	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NHY65_07565	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
NHY65_07610	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHY65_07615	COG1077	Cell shape determining protein MreB Mrl
NHY65_07620	COG1792	Involved in formation and maintenance of cell shape
NHY65_07625	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NHY65_07630	COG0424	maF-like protein
NHY65_07645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NHY65_07655	COG0560	Phosphoserine phosphatase
NHY65_07665	COG2249	NAD(P)H dehydrogenase (quinone) activity
NHY65_07690	COG2207	Transcriptional regulator
NHY65_07720	COG0142	geranyltranstransferase activity
NHY65_07725	COG2315	Protein conserved in bacteria
NHY65_07740	COG1752	Esterase of the alpha-beta hydrolase superfamily
NHY65_07760	COG2194	sulfuric ester hydrolase activity
NHY65_07765	COG0745	RESPONSE REGULATOR receiver
NHY65_07770	COG0642	Histidine kinase
NHY65_07785	COG0583	DNA-binding transcription factor activity
NHY65_07815	COG1028	Short-chain dehydrogenase reductase Sdr
NHY65_07825	COG0393	Putative heavy-metal-binding
NHY65_07830	COG0393	Putative heavy-metal-binding
NHY65_07835	COG1538	Outer membrane efflux protein
NHY65_07845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NHY65_07850	COG0671	phosphoesterase, PA-phosphatase related
NHY65_07880	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NHY65_07895	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NHY65_07895	COG1648	precorrin-2 dehydrogenase activity
NHY65_07900	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NHY65_07905	COG1733	regulation of RNA biosynthetic process
NHY65_07930	COG0321	lipoyl(octanoyl) transferase activity
NHY65_07935	COG2921	Belongs to the UPF0250 family
NHY65_07975	COG2009	succinate dehydrogenase
NHY65_07980	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NHY65_07990	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NHY65_08035	COG2354	Protein conserved in bacteria
NHY65_08040	COG2321	neutral zinc metallopeptidase
NHY65_08060	COG2843	Capsule synthesis protein
NHY65_08075	COG0589	response to stress
NHY65_08095	COG0505	Belongs to the CarA family
NHY65_08125	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NHY65_08175	COG0477	Major facilitator Superfamily
NHY65_08180	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NHY65_08195	COG1597	lipid kinase activity
NHY65_08200	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NHY65_08225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NHY65_08250	COG0741	lytic transglycosylase activity
NHY65_08315	COG0778	Nitroreductase
NHY65_08335	COG0243	molybdopterin cofactor binding
NHY65_08340	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NHY65_08345	COG3339	Conserved Protein
NHY65_08380	COG0019	diaminopimelate decarboxylase activity
NHY65_08390	COG1280	lysine exporter protein (LysE YggA)
NHY65_08395	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NHY65_08445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NHY65_08480	COG4591	ABC-type transport system involved in lipoprotein release permease component
NHY65_08485	COG1136	(ABC) transporter
NHY65_08510	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NHY65_08510	COG0616	signal peptide processing
NHY65_08515	COG0596	Alpha beta hydrolase
NHY65_08520	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NHY65_08565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHY65_08605	COG0824	Thioesterase
NHY65_08610	COG1473	amidohydrolase
NHY65_08630	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHY65_08630	COG0047	phosphoribosylformylglycinamidine synthase activity
NHY65_08635	COG2814	Major facilitator Superfamily
NHY65_08650	COG1024	Enoyl-CoA hydratase
NHY65_08655	COG1051	belongs to the nudix hydrolase family
NHY65_08655	COG1056	cytidyltransferase-related domain
NHY65_08665	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NHY65_08680	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NHY65_08695	COG4625	pathogenesis
NHY65_08700	COG0583	DNA-binding transcription factor activity
NHY65_08705	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NHY65_08710	COG4208	sulfate ABC transporter
NHY65_08715	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NHY65_08725	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NHY65_08730	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NHY65_08735	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NHY65_08755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NHY65_08770	COG0681	Belongs to the peptidase S26 family
NHY65_08785	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NHY65_08795	COG1381	Involved in DNA repair and RecF pathway recombination
NHY65_08800	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NHY65_08840	COG0436	Aminotransferase
NHY65_08860	COG0556	nucleotide-excision repair
NHY65_08915	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NHY65_09245	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHY65_09310	COG0415	Belongs to the DNA photolyase family
NHY65_09325	COG1686	Belongs to the peptidase S11 family
NHY65_09340	COG1187	pseudouridine synthase activity
NHY65_09365	COG0477	Major facilitator Superfamily
NHY65_09370	COG0583	DNA-binding transcription factor activity
NHY65_09375	COG1823	symporter activity
NHY65_09410	COG0352	thiamine-phosphate diphosphorylase activity
NHY65_09445	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NHY65_09460	COG1309	transcriptional regulator
NHY65_09470	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NHY65_09485	COG1522	sequence-specific DNA binding
NHY65_09490	COG3961	Belongs to the TPP enzyme family
NHY65_09495	COG1113	amino acid transport
NHY65_09500	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NHY65_09505	COG0573	inorganic phosphate transmembrane transporter activity
NHY65_09515	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NHY65_09550	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NHY65_09555	COG1686	Belongs to the peptidase S11 family
NHY65_09580	COG0583	DNA-binding transcription factor activity
NHY65_09585	COG1067	ATP-dependent peptidase activity
NHY65_09630	COG1966	Carbon starvation protein
NHY65_09635	COG2879	small protein
NHY65_09670	COG2508	Transcriptional regulator
NHY65_09670	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NHY65_09700	COG0583	DNA-binding transcription factor activity
NHY65_09720	COG1012	belongs to the aldehyde dehydrogenase family
NHY65_09735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NHY65_09780	COG2814	Major facilitator Superfamily
NHY65_09785	COG4948	Mandelate Racemase Muconate Lactonizing
NHY65_09795	COG1309	transcriptional regulator
NHY65_09815	COG1741	Belongs to the pirin family
NHY65_09825	COG2964	Protein conserved in bacteria
NHY65_09840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NHY65_09845	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHY65_09850	COG4605	iron ion homeostasis
NHY65_09855	COG4604	ABC transporter, ATP-binding protein
NHY65_09860	COG4607	ABC-type enterochelin transport system periplasmic component
NHY65_09865	COG4774	siderophore transport
NHY65_09875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NHY65_09885	COG1535	isochorismatase
NHY65_09885	COG3433	isochorismatase activity
NHY65_09900	COG1132	(ABC) transporter
NHY65_09910	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
NHY65_09960	COG0302	gtp cyclohydrolase
NHY65_09970	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NHY65_10005	COG0512	Glutamine amidotransferase of anthranilate synthase
NHY65_10020	COG0174	glutamine synthetase
NHY65_10030	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NHY65_10065	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NHY65_10070	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NHY65_10075	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NHY65_10095	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NHY65_10100	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NHY65_10105	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NHY65_10125	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NHY65_10130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NHY65_10140	COG2223	nitrite transmembrane transporter activity
NHY65_10150	COG0024	Methionine aminopeptidase
NHY65_10155	COG0052	Belongs to the universal ribosomal protein uS2 family
NHY65_10195	COG2951	lytic endotransglycosylase activity
NHY65_10200	COG0772	Belongs to the SEDS family
NHY65_10215	COG0842	Transport permease protein
NHY65_10220	COG1131	(ABC) transporter
NHY65_10265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NHY65_10280	COG4215	(ABC) transporter
NHY65_10285	COG4160	amino acid transport
NHY65_10290	COG4598	ABC transporter
NHY65_10300	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NHY65_10305	COG0826	peptidase U32
NHY65_10310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NHY65_10325	COG1720	tRNA m6t6A37 methyltransferase activity
NHY65_10350	COG0642	Histidine kinase
NHY65_10360	COG0494	nUDIX hydrolase
NHY65_10370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NHY65_10375	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NHY65_10380	COG3139	Protein of unknown function (DUF1315)
NHY65_10385	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NHY65_10390	COG1301	dicarboxylic acid transport
NHY65_10400	COG2819	hydrolase of the alpha beta superfamily
NHY65_10410	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NHY65_10420	COG2195	Cleaves the N-terminal amino acid of tripeptides
NHY65_10425	COG1234	tRNA 3'-trailer cleavage
NHY65_10455	COG2363	Small membrane protein
NHY65_10480	COG0513	Belongs to the DEAD box helicase family
NHY65_10490	COG0778	Nitroreductase
NHY65_10520	COG1286	toxin biosynthetic process
NHY65_10550	COG1610	YqeY-like protein
NHY65_10715	COG0488	(ABC) transporter
NHY65_10720	COG3173	Aminoglycoside phosphotransferase
NHY65_10730	COG2433	Pfam Transposase IS66
NHY65_10750	COG1301	dicarboxylic acid transport
NHY65_10760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NHY65_10765	COG2011	ABC-type metal ion transport system permease component
NHY65_10770	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NHY65_10775	COG1464	Belongs to the NlpA lipoprotein family
NHY65_10785	COG0138	bifunctional purine biosynthesis protein purh
NHY65_10790	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NHY65_10840	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NHY65_10845	COG0305	Participates in initiation and elongation during chromosome replication
NHY65_10870	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NHY65_10880	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NHY65_10885	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NHY65_10915	COG1215	transferase activity, transferring glycosyl groups
NHY65_10920	COG3658	cytochrome
NHY65_10930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHY65_10970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NHY65_10985	COG1960	acyl-CoA dehydrogenase activity
NHY65_10990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NHY65_10995	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NHY65_11025	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NHY65_11035	COG2205	protein histidine kinase activity
NHY65_11040	COG0745	RESPONSE REGULATOR receiver
NHY65_11045	COG0174	glutamine synthetase
NHY65_11065	COG0729	surface antigen
NHY65_11090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NHY65_11110	COG0583	DNA-binding transcription factor activity
NHY65_11125	COG1187	pseudouridine synthase activity
NHY65_11145	COG0802	atpase or kinase
NHY65_11150	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NHY65_11160	COG1923	regulation of RNA biosynthetic process
NHY65_11165	COG0697	spore germination
NHY65_11190	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NHY65_11195	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NHY65_11195	COG0519	Catalyzes the synthesis of GMP from XMP
NHY65_11200	COG4302	ethanolamine ammonia-lyase activity
NHY65_11205	COG4303	Ethanolamine ammonia lyase large subunit
NHY65_11210	COG0531	amino acid
NHY65_11230	COG1454	alcohol dehydrogenase
NHY65_11265	COG0308	aminopeptidase N
NHY65_11275	COG4221	oxidoreductase activity
NHY65_11285	COG1605	Chorismate mutase
NHY65_11305	COG1309	transcriptional regulator
NHY65_11350	COG4773	Receptor
NHY65_11370	COG0488	(ABC) transporter
NHY65_11375	COG0589	response to stress
NHY65_11400	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NHY65_11410	COG3135	benzoate transporter
NHY65_11415	COG1522	sequence-specific DNA binding
NHY65_11425	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NHY65_11430	COG0583	DNA-binding transcription factor activity
NHY65_11440	COG0183	Belongs to the thiolase family
NHY65_11455	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NHY65_11470	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHY65_11480	COG0824	Thioesterase
NHY65_11485	COG1454	alcohol dehydrogenase
NHY65_11495	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NHY65_11515	COG0069	glutamate synthase activity
NHY65_11535	COG2814	Major facilitator Superfamily
NHY65_11550	COG0511	ligase activity, forming carbon-carbon bonds
NHY65_11570	COG1116	anion transmembrane transporter activity
NHY65_11570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NHY65_11575	COG0745	RESPONSE REGULATOR receiver
NHY65_11595	COG0243	molybdopterin cofactor binding
NHY65_11605	COG0243	molybdopterin cofactor binding
NHY65_11610	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NHY65_11625	COG0521	Mo-molybdopterin cofactor biosynthetic process
NHY65_11625	COG0315	cyclic pyranopterin monophosphate synthase activity
NHY65_11640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NHY65_11645	COG0697	spore germination
NHY65_11665	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
NHY65_11670	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NHY65_11725	COG2204	response regulator
NHY65_11730	COG3852	Histidine kinase
NHY65_11755	COG0575	Belongs to the CDS family
NHY65_11790	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NHY65_11805	COG2137	regulation of response to DNA damage stimulus
NHY65_11815	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NHY65_11820	COG1011	Hydrolase
NHY65_11845	COG1522	sequence-specific DNA binding
NHY65_11855	COG1113	amino acid transport
NHY65_11875	COG0659	secondary active sulfate transmembrane transporter activity
NHY65_11880	COG2135	peptidase activity
NHY65_11895	COG5001	Diguanylate cyclase
NHY65_11895	COG3300	MHYT domain
NHY65_11930	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NHY65_11930	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NHY65_11965	COG0024	Methionine aminopeptidase
NHY65_11970	COG0583	DNA-binding transcription factor activity
NHY65_11980	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NHY65_11985	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NHY65_11990	COG0517	IMP dehydrogenase activity
NHY65_11990	COG0516	GMP reductase activity
NHY65_12015	COG0552	protein localization to endoplasmic reticulum
NHY65_12025	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
NHY65_12040	COG4890	Cyd operon protein YbgT
NHY65_12045	COG1294	oxidase, subunit
NHY65_12060	COG1585	Membrane protein implicated in regulation of membrane protease activity
NHY65_12075	COG4774	siderophore transport
NHY65_12090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NHY65_12095	COG0569	domain protein
NHY65_12100	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NHY65_12130	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NHY65_12135	COG0542	response to heat
NHY65_12160	COG1902	pentaerythritol trinitrate reductase activity
NHY65_12160	COG0446	pyridine nucleotide-disulphide oxidoreductase
NHY65_12210	COG2323	membrane
NHY65_12215	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NHY65_12225	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NHY65_12230	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NHY65_12235	COG0183	Belongs to the thiolase family
NHY65_12240	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NHY65_12245	COG0596	Alpha beta hydrolase
NHY65_12255	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NHY65_12265	COG3485	protocatechuate 3,4-dioxygenase
NHY65_12270	COG0710	3-dehydroquinate dehydratase activity
NHY65_12275	COG3420	alginic acid biosynthetic process
NHY65_12285	COG4993	Dehydrogenase
NHY65_12295	COG2391	methyltransferase activity
NHY65_12310	COG1414	Transcriptional regulator
NHY65_12315	COG0583	DNA-binding transcription factor activity
NHY65_12320	COG1960	acyl-CoA dehydrogenase activity
NHY65_12345	COG2814	Major facilitator Superfamily
NHY65_12355	COG0154	amidase activity
NHY65_12385	COG1028	Short-chain dehydrogenase reductase Sdr
NHY65_12395	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NHY65_12405	COG3733	amine oxidase
NHY65_12415	COG1012	belongs to the aldehyde dehydrogenase family
NHY65_12425	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NHY65_12430	COG0183	Belongs to the thiolase family
NHY65_12435	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NHY65_12440	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NHY65_12450	COG4829	muconolactone delta-isomerase
NHY65_12460	COG0583	DNA-binding transcription factor activity
NHY65_12470	COG2186	Transcriptional regulator
NHY65_12490	COG1012	belongs to the aldehyde dehydrogenase family
NHY65_12510	COG1960	acyl-CoA dehydrogenase activity
NHY65_12520	COG3829	transcription factor binding
NHY65_12530	COG3162	membrane
NHY65_12545	COG1012	belongs to the aldehyde dehydrogenase family
NHY65_12580	COG1846	Transcriptional regulator
NHY65_12585	COG0446	pyridine nucleotide-disulphide oxidoreductase
NHY65_12585	COG1902	pentaerythritol trinitrate reductase activity
NHY65_12595	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NHY65_12625	COG1309	transcriptional regulator
NHY65_12635	COG1335	isochorismatase
NHY65_12640	COG0583	DNA-binding transcription factor activity
NHY65_12650	COG0475	glutathione-regulated potassium exporter activity
NHY65_12650	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NHY65_12675	COG3210	domain, Protein
NHY65_12705	COG2188	Transcriptional regulator
NHY65_12720	COG0583	DNA-binding transcription factor activity
NHY65_12750	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NHY65_12790	COG1566	PFAM secretion protein HlyD family protein
NHY65_12805	COG1012	belongs to the aldehyde dehydrogenase family
NHY65_12810	COG0129	dihydroxy-acid dehydratase activity
NHY65_12820	COG0583	DNA-binding transcription factor activity
NHY65_12825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NHY65_12855	COG1064	alcohol dehydrogenase
NHY65_12865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHY65_12870	COG1120	ATPase activity
NHY65_12890	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHY65_13015	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NHY65_13065	COG1028	Short-chain dehydrogenase reductase Sdr
NHY65_13080	COG2207	Transcriptional regulator
NHY65_13095	COG0745	RESPONSE REGULATOR receiver
NHY65_13100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NHY65_13105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NHY65_13110	COG1538	Outer membrane efflux protein
NHY65_13140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NHY65_13165	COG3539	Fimbrial protein
NHY65_13195	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
NHY65_13205	COG0753	catalase activity
NHY65_13220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHY65_13280	COG3433	isochorismatase activity
NHY65_13280	COG1535	isochorismatase
NHY65_13285	COG1028	Short-chain dehydrogenase reductase Sdr
NHY65_13290	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NHY65_13295	COG4149	molybdate abc transporter
NHY65_13300	COG0725	ABC transporter, periplasmic molybdate-binding protein
NHY65_13315	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
NHY65_13345	COG1028	Short-chain dehydrogenase reductase Sdr
NHY65_13360	COG2207	Transcriptional regulator
NHY65_13370	COG1028	Short-chain dehydrogenase reductase Sdr
NHY65_13375	COG2610	gluconate transmembrane transporter activity
NHY65_13385	COG0583	DNA-binding transcription factor activity
NHY65_13395	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NHY65_13405	COG0183	Belongs to the thiolase family
NHY65_13415	COG0583	DNA-binding transcription factor activity
NHY65_13440	COG0477	Major facilitator Superfamily
NHY65_13460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NHY65_13465	COG4521	taurine ABC transporter
NHY65_13480	COG2188	Transcriptional regulator
NHY65_13490	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NHY65_13495	COG1733	regulation of RNA biosynthetic process
NHY65_13515	COG0730	response to heat
NHY65_13530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NHY65_13530	COG3453	Protein conserved in bacteria
NHY65_13540	COG3781	membrane
NHY65_13545	COG1063	alcohol dehydrogenase
NHY65_13560	COG0508	dehydrogenase complex catalyzes the overall conversion of
NHY65_13570	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NHY65_13575	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NHY65_13590	COG3706	GGDEF domain
NHY65_13605	COG0133	tryptophan synthase activity
NHY65_13615	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NHY65_13650	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NHY65_13735	COG0842	Transport permease protein
NHY65_13740	COG0842	Transport permease protein
NHY65_13760	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NHY65_13785	COG0730	response to heat
NHY65_13790	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NHY65_13810	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NHY65_13825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NHY65_13870	COG4264	IucA IucC family
NHY65_13890	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NHY65_13905	COG1960	acyl-CoA dehydrogenase activity
NHY65_13910	COG1960	acyl-CoA dehydrogenase activity
NHY65_13920	COG2207	Transcriptional regulator
NHY65_13925	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NHY65_13930	COG0776	regulation of translation
NHY65_13955	COG0822	iron-sulfur transferase activity
NHY65_13990	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NHY65_14010	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NHY65_14015	COG0702	epimerase
NHY65_14050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHY65_14060	COG0339	signal peptide processing
NHY65_14110	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NHY65_14115	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NHY65_14145	COG0776	regulation of translation
NHY65_14210	COG0084	hydrolase, TatD family'
NHY65_14230	COG1663	tetraacyldisaccharide 4'-kinase activity
NHY65_14235	COG1132	(ABC) transporter
NHY65_14250	COG1475	DNA binding
NHY65_14255	COG1192	Involved in chromosome partitioning
NHY65_14280	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NHY65_14285	COG0191	fructose-bisphosphate aldolase activity
NHY65_14310	COG2850	peptidyl-arginine hydroxylation
NHY65_14320	COG0640	Transcriptional regulator
NHY65_14330	COG3619	membrane
NHY65_14335	COG3122	Protein conserved in bacteria
NHY65_14340	COG1132	(ABC) transporter
NHY65_14360	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NHY65_14365	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NHY65_14375	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NHY65_14375	COG0506	proline dehydrogenase activity
NHY65_14375	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NHY65_14380	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NHY65_14395	COG3698	Phosphodiester glycosidase
NHY65_14405	COG2353	YceI-like domain
NHY65_14460	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NHY65_14460	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NHY65_14485	COG3539	Fimbrial protein
NHY65_14515	COG0697	spore germination
NHY65_14535	COG0583	DNA-binding transcription factor activity
NHY65_14555	COG1309	transcriptional regulator
NHY65_14570	COG1522	sequence-specific DNA binding
NHY65_14585	COG0765	amino acid transport
NHY65_14590	COG0765	amino acid transport
NHY65_14630	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NHY65_14635	COG2011	ABC-type metal ion transport system permease component
NHY65_14640	COG0012	GTP binding
NHY65_14705	COG0386	Belongs to the glutathione peroxidase family
NHY65_14715	COG0436	Aminotransferase
NHY65_14755	COG3634	alkyl hydroperoxide reductase activity
NHY65_14770	COG0583	DNA-binding transcription factor activity
NHY65_14775	COG0798	PFAM Bile acid sodium symporter
NHY65_14780	COG0640	Transcriptional regulator
NHY65_14795	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NHY65_14805	COG0583	DNA-binding transcription factor activity
NHY65_14815	COG1953	Uracil, thiamine, allantoin
NHY65_14835	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NHY65_14840	COG4521	taurine ABC transporter
NHY65_14870	COG1271	oxidase subunit
NHY65_14875	COG1294	oxidase, subunit
NHY65_14905	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NHY65_14925	COG3052	prosthetic group binding
NHY65_14940	COG2814	Major facilitator Superfamily
NHY65_14960	COG1346	cytolysis
NHY65_14970	COG0583	DNA-binding transcription factor activity
NHY65_14975	COG0625	glutathione transferase activity
NHY65_14980	COG0625	glutathione transferase activity
NHY65_14985	COG0583	DNA-binding transcription factor activity
NHY65_15000	COG1045	serine acetyltransferase
NHY65_15005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NHY65_15020	COG1280	lysine exporter protein (LysE YggA)
NHY65_15045	COG1126	abc transporter atp-binding protein
NHY65_15050	COG0765	amino acid transport
NHY65_15055	COG0765	amino acid transport
NHY65_15105	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NHY65_15175	COG0583	DNA-binding transcription factor activity
NHY65_15200	COG1309	transcriptional regulator
NHY65_15205	COG1960	acyl-CoA dehydrogenase activity
NHY65_15210	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NHY65_15215	COG1024	Enoyl-CoA hydratase
NHY65_15220	COG4770	biotin carboxylase activity
NHY65_15230	COG0583	DNA-binding transcription factor activity
NHY65_15255	COG2814	Major facilitator Superfamily
NHY65_15265	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NHY65_15275	COG2814	Major facilitator Superfamily
NHY65_15285	COG1024	Enoyl-CoA hydratase
NHY65_15290	COG1028	Short-chain dehydrogenase reductase Sdr
NHY65_15295	COG1250	3-hydroxyacyl-CoA dehydrogenase
NHY65_15300	COG0183	Belongs to the thiolase family
NHY65_15310	COG2814	Major facilitator Superfamily
NHY65_15320	COG1024	Enoyl-CoA hydratase
NHY65_15340	COG2814	Major facilitator Superfamily
NHY65_15345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NHY65_15365	COG3842	ATPase activity
NHY65_15370	COG1840	ABC-type Fe3 transport system, periplasmic component
NHY65_15380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NHY65_15385	COG1414	Transcriptional regulator
NHY65_15395	COG0583	DNA-binding transcription factor activity
NHY65_15400	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NHY65_15415	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NHY65_15430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHY65_15435	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NHY65_15440	COG2267	carboxylic ester hydrolase activity
NHY65_15460	COG3038	cytochrome b561
NHY65_15465	COG0753	catalase activity
NHY65_15500	COG2050	protein possibly involved in aromatic compounds catabolism
NHY65_15510	COG3327	negative regulation of DNA-templated transcription, initiation
NHY65_15515	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NHY65_15520	COG0183	Belongs to the thiolase family
NHY65_15525	COG1250	3-hydroxyacyl-CoA dehydrogenase
NHY65_15530	COG1024	Enoyl-CoA hydratase
NHY65_15540	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NHY65_15545	COG2151	metal-sulfur cluster biosynthetic enzyme
NHY65_15550	COG3396	Phenylacetate-CoA oxygenase
NHY65_15555	COG3460	Phenylacetate-CoA oxygenase
NHY65_15560	COG3396	Phenylacetate-CoA oxygenase
NHY65_15570	COG1760	l-serine dehydratase
NHY65_15575	COG0531	amino acid
NHY65_15580	COG1012	belongs to the aldehyde dehydrogenase family
NHY65_15625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NHY65_15635	COG0789	Transcriptional regulator
NHY65_15650	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NHY65_15665	COG2807	transmembrane transport
NHY65_15670	COG0590	tRNA wobble adenosine to inosine editing
NHY65_15790	COG1116	anion transmembrane transporter activity
NHY65_15795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NHY65_15805	COG0864	Transcriptional regulator
NHY65_15825	COG2249	NAD(P)H dehydrogenase (quinone) activity
NHY65_15830	COG0439	Biotin carboxylase
NHY65_15845	COG1063	alcohol dehydrogenase
NHY65_15855	COG1309	transcriptional regulator
NHY65_15875	COG0038	chloride channel
NHY65_15900	COG1914	H( )-stimulated, divalent metal cation uptake system
NHY65_15905	COG0583	DNA-binding transcription factor activity
NHY65_15955	COG1250	3-hydroxyacyl-CoA dehydrogenase
NHY65_15975	COG2814	Major facilitator Superfamily
NHY65_15990	COG1560	Kdo2-lipid A biosynthetic process
NHY65_16000	COG5006	permease, DMT superfamily
NHY65_16005	COG1522	sequence-specific DNA binding
NHY65_16020	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NHY65_16030	COG4122	O-methyltransferase activity
NHY65_16060	COG1538	Outer membrane efflux protein
NHY65_16070	COG1137	ATPase activity
NHY65_16075	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NHY65_16085	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NHY65_16090	COG0517	IMP dehydrogenase activity
NHY65_16090	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NHY65_16125	COG2814	Major facilitator Superfamily
NHY65_16160	COG1278	Cold shock
NHY65_16165	COG1280	lysine exporter protein (LysE YggA)
NHY65_16195	COG1570	exodeoxyribonuclease VII activity
NHY65_16245	COG0583	DNA-binding transcription factor activity
NHY65_16255	COG4638	Rieske (2fe-2S)
NHY65_16260	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
NHY65_16265	COG0633	Ferredoxin
NHY65_16265	COG0543	2 iron, 2 sulfur cluster binding
NHY65_16270	COG1028	Short-chain dehydrogenase reductase Sdr
NHY65_16300	COG0450	alkyl hydroperoxide reductase
NHY65_16310	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NHY65_16320	COG3634	alkyl hydroperoxide reductase activity
NHY65_16340	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NHY65_16345	COG0625	glutathione transferase activity
NHY65_16355	COG2885	chlorophyll binding
NHY65_16390	COG0542	response to heat
NHY65_16410	COG1765	OsmC-like protein
NHY65_16430	COG0667	Aldo Keto reductase
NHY65_16445	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NHY65_16455	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NHY65_16465	COG0527	aspartate kinase activity
NHY65_16475	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHY65_16485	COG3038	cytochrome b561
NHY65_16490	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NHY65_16495	COG2252	PERMEase
NHY65_16505	COG2072	flavoprotein involved in K transport
NHY65_16520	COG1741	Belongs to the pirin family
NHY65_16525	COG1309	transcriptional regulator
NHY65_16535	COG0300	oxidoreductase activity
NHY65_16570	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NHY65_16630	COG1012	belongs to the aldehyde dehydrogenase family
NHY65_16650	COG0531	amino acid
NHY65_16660	COG1113	amino acid transport
NHY65_16700	COG3209	COG3209 Rhs family protein
NHY65_16740	COG4269	membrane
NHY65_16765	COG5001	Diguanylate cyclase
NHY65_16765	COG4251	negative regulation of phosphorylation
NHY65_16765	COG2203	Gaf domain
NHY65_16765	COG3706	GGDEF domain
NHY65_16795	COG4172	Belongs to the ABC transporter superfamily
NHY65_16800	COG4239	(ABC) transporter, permease
NHY65_16805	COG4174	ABC transporter (Permease)
NHY65_16820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NHY65_16860	COG0583	DNA-binding transcription factor activity
NHY65_16865	COG1279	arginine transmembrane transporter activity
NHY65_16885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NHY65_16890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NHY65_16980	COG1196	nuclear chromosome segregation
NHY65_16980	COG0741	lytic transglycosylase activity
NHY65_16980	COG0739	heme binding
NHY65_17040	COG4695	Portal protein
NHY65_17140	COG0305	Participates in initiation and elongation during chromosome replication
NHY65_17145	COG0305	Participates in initiation and elongation during chromosome replication
NHY65_17215	COG2194	sulfuric ester hydrolase activity
NHY65_17260	COG0739	heme binding
NHY65_17585	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NHY65_17625	COG2878	Part of a membrane complex involved in electron transport
NHY65_17630	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NHY65_17660	COG0742	ribosomal rna small subunit methyltransferase
NHY65_17675	COG0830	nickel cation binding
NHY65_17685	COG0804	urea catabolic process
NHY65_17730	COG2851	Citrate transporter
NHY65_17780	COG1773	rubredoxin
NHY65_17785	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NHY65_17795	COG0583	DNA-binding transcription factor activity
NHY65_17825	COG4181	ATPase activity
NHY65_17870	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NHY65_17890	COG0306	phosphate transporter
NHY65_17900	COG3958	Transketolase
NHY65_17905	COG3959	Transketolase, thiamine diphosphate binding domain
NHY65_17910	COG2271	Major facilitator Superfamily
NHY65_17915	COG1028	Short-chain dehydrogenase reductase Sdr
NHY65_17920	COG0583	DNA-binding transcription factor activity
NHY65_17945	COG2066	Belongs to the glutaminase family
NHY65_17950	COG0242	peptide deformylase activity
NHY65_17955	COG0477	Major facilitator Superfamily
NHY65_17965	COG0028	Belongs to the TPP enzyme family
NHY65_17980	COG1028	Short-chain dehydrogenase reductase Sdr
NHY65_17985	COG2267	carboxylic ester hydrolase activity
NHY65_17995	COG2271	Major facilitator Superfamily
NHY65_18000	COG0446	pyridine nucleotide-disulphide oxidoreductase
NHY65_18010	COG1028	Short-chain dehydrogenase reductase Sdr
NHY65_18030	COG1414	Transcriptional regulator
NHY65_18045	COG1024	Enoyl-CoA hydratase
NHY65_18055	COG1215	transferase activity, transferring glycosyl groups
NHY65_18060	COG0726	polysaccharide deacetylase
NHY65_18060	COG1649	PFAM Uncharacterised BCR, COG1649
NHY65_18070	COG4681	YaeQ
NHY65_18090	COG1607	acyl-coa hydrolase
NHY65_18100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NHY65_18105	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NHY65_18110	COG1309	transcriptional regulator
NHY65_18135	COG2040	homocysteine
NHY65_18140	COG0531	amino acid
NHY65_18195	COG1595	DNA-templated transcription, initiation
NHY65_18210	COG0477	Major facilitator Superfamily
NHY65_18260	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHY65_18390	COG2026	Addiction module toxin, RelE StbE family
NHY65_18620	COG1484	DNA-dependent DNA replication
NHY65_18735	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NHY65_18775	COG2814	Major facilitator Superfamily
NHY65_18785	COG2050	protein possibly involved in aromatic compounds catabolism
NHY65_18800	COG1090	epimerase
NHY65_18820	COG0420	3'-5' exonuclease activity
NHY65_18845	COG0735	belongs to the Fur family
NHY65_18850	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NHY65_18885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NHY65_18900	COG2885	chlorophyll binding
NHY65_18940	COG1280	lysine exporter protein (LysE YggA)
NHY65_18945	COG1674	ftsk spoiiie
NHY65_18945	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NHY65_18950	COG0492	ferredoxin-NADP+ reductase activity
NHY65_18965	COG0456	acetyltransferase
NHY65_19010	COG1981	membrane
NHY65_19025	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NHY65_19025	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NHY65_19045	COG1012	belongs to the aldehyde dehydrogenase family
NHY65_19055	COG0657	acetylesterase activity
NHY65_19070	COG0583	DNA-binding transcription factor activity
NHY65_19090	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NHY65_19115	COG0564	pseudouridine synthase activity
NHY65_19125	COG0358	DNA primase activity
NHY65_19140	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NHY65_19195	COG0484	heat shock protein binding
NHY65_19290	COG3853	Toxic anion resistance protein (TelA)
NHY65_19305	COG1475	DNA binding
NHY65_19380	COG1525	nuclease
NHY65_19560	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NHY65_19600	COG0741	lytic transglycosylase activity