locus-tag	class	description
NHY68_00040	COG1250	3-hydroxyacyl-CoA dehydrogenase
NHY68_00075	COG1560	Kdo2-lipid A biosynthetic process
NHY68_00085	COG5006	permease, DMT superfamily
NHY68_00090	COG1522	sequence-specific DNA binding
NHY68_00105	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NHY68_00115	COG4122	O-methyltransferase activity
NHY68_00145	COG1538	Outer membrane efflux protein
NHY68_00150	COG1137	ATPase activity
NHY68_00165	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NHY68_00170	COG0517	IMP dehydrogenase activity
NHY68_00170	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NHY68_00240	COG1278	Cold shock
NHY68_00275	COG1570	exodeoxyribonuclease VII activity
NHY68_00340	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
NHY68_00345	COG0543	2 iron, 2 sulfur cluster binding
NHY68_00345	COG0633	Ferredoxin
NHY68_00350	COG1028	Short-chain dehydrogenase reductase Sdr
NHY68_00355	COG3135	benzoate transporter
NHY68_00375	COG1643	Atp-dependent helicase
NHY68_00380	COG0450	alkyl hydroperoxide reductase
NHY68_00390	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NHY68_00420	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NHY68_00425	COG0625	glutathione transferase activity
NHY68_00435	COG2885	chlorophyll binding
NHY68_00470	COG0542	response to heat
NHY68_00490	COG1765	OsmC-like protein
NHY68_00510	COG0667	Aldo Keto reductase
NHY68_00535	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NHY68_00565	COG3038	cytochrome b561
NHY68_00570	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NHY68_00600	COG1741	Belongs to the pirin family
NHY68_00605	COG1309	transcriptional regulator
NHY68_00615	COG0300	oxidoreductase activity
NHY68_00635	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NHY68_00685	COG1012	belongs to the aldehyde dehydrogenase family
NHY68_00715	COG1113	amino acid transport
NHY68_00755	COG3209	COG3209 Rhs family protein
NHY68_00785	COG4269	membrane
NHY68_00800	COG1902	pentaerythritol trinitrate reductase activity
NHY68_00800	COG0446	pyridine nucleotide-disulphide oxidoreductase
NHY68_00810	COG3706	GGDEF domain
NHY68_00810	COG2203	Gaf domain
NHY68_00810	COG5001	Diguanylate cyclase
NHY68_00810	COG4251	negative regulation of phosphorylation
NHY68_00820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NHY68_00865	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NHY68_00985	COG1610	YqeY-like protein
NHY68_00990	COG4783	chaperone-mediated protein folding
NHY68_01015	COG1286	toxin biosynthetic process
NHY68_01045	COG0778	Nitroreductase
NHY68_01055	COG0513	Belongs to the DEAD box helicase family
NHY68_01080	COG2363	Small membrane protein
NHY68_01115	COG2195	Cleaves the N-terminal amino acid of tripeptides
NHY68_01125	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NHY68_01135	COG2819	hydrolase of the alpha beta superfamily
NHY68_01140	COG1960	acyl-CoA dehydrogenase activity
NHY68_01145	COG1301	dicarboxylic acid transport
NHY68_01150	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NHY68_01155	COG3139	Protein of unknown function (DUF1315)
NHY68_01160	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NHY68_01165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NHY68_01175	COG0494	nUDIX hydrolase
NHY68_01185	COG0642	Histidine kinase
NHY68_01200	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NHY68_01210	COG1720	tRNA m6t6A37 methyltransferase activity
NHY68_01225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NHY68_01230	COG0826	peptidase U32
NHY68_01235	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NHY68_01250	COG4160	amino acid transport
NHY68_01255	COG4215	(ABC) transporter
NHY68_01270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NHY68_01315	COG1131	(ABC) transporter
NHY68_01320	COG0842	Transport permease protein
NHY68_01335	COG0772	Belongs to the SEDS family
NHY68_01365	COG2207	Transcriptional regulator
NHY68_01380	COG0052	Belongs to the universal ribosomal protein uS2 family
NHY68_01385	COG0024	Methionine aminopeptidase
NHY68_01410	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NHY68_01430	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NHY68_01440	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NHY68_01460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NHY68_01465	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NHY68_01470	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NHY68_01505	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NHY68_01515	COG0174	glutamine synthetase
NHY68_01530	COG0512	Glutamine amidotransferase of anthranilate synthase
NHY68_01535	COG0308	aminopeptidase N
NHY68_01575	COG0302	gtp cyclohydrolase
NHY68_01600	COG3739	integral membrane protein
NHY68_01615	COG1169	isochorismate synthase
NHY68_01625	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
NHY68_01630	COG1132	(ABC) transporter
NHY68_01655	COG1021	2,3-dihydroxybenzoate-AMP ligase
NHY68_01660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NHY68_01670	COG4774	siderophore transport
NHY68_01675	COG4607	ABC-type enterochelin transport system periplasmic component
NHY68_01680	COG4604	ABC transporter, ATP-binding protein
NHY68_01685	COG4605	iron ion homeostasis
NHY68_01690	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHY68_01710	COG2964	Protein conserved in bacteria
NHY68_01720	COG1741	Belongs to the pirin family
NHY68_01740	COG1309	transcriptional regulator
NHY68_01750	COG4948	Mandelate Racemase Muconate Lactonizing
NHY68_01755	COG2814	Major facilitator Superfamily
NHY68_01790	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NHY68_01790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NHY68_01795	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NHY68_01805	COG1012	belongs to the aldehyde dehydrogenase family
NHY68_01820	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NHY68_01825	COG0583	DNA-binding transcription factor activity
NHY68_01830	COG1113	amino acid transport
NHY68_01850	COG2508	Transcriptional regulator
NHY68_01850	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NHY68_01885	COG2879	small protein
NHY68_01890	COG1966	Carbon starvation protein
NHY68_01940	COG0583	DNA-binding transcription factor activity
NHY68_01965	COG1686	Belongs to the peptidase S11 family
NHY68_02015	COG0573	inorganic phosphate transmembrane transporter activity
NHY68_02025	COG1113	amino acid transport
NHY68_02030	COG3961	Belongs to the TPP enzyme family
NHY68_02035	COG1522	sequence-specific DNA binding
NHY68_02050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NHY68_02060	COG1309	transcriptional regulator
NHY68_02110	COG0352	thiamine-phosphate diphosphorylase activity
NHY68_02135	COG0612	Peptidase, M16
NHY68_02150	COG0583	DNA-binding transcription factor activity
NHY68_02180	COG1187	pseudouridine synthase activity
NHY68_02195	COG1686	Belongs to the peptidase S11 family
NHY68_02200	COG1252	NADH dehydrogenase
NHY68_02225	COG1215	transferase activity, transferring glycosyl groups
NHY68_02255	COG2070	2-Nitropropane dioxygenase
NHY68_02310	COG0556	nucleotide-excision repair
NHY68_02330	COG0436	Aminotransferase
NHY68_02360	COG4221	oxidoreductase activity
NHY68_02375	COG1381	Involved in DNA repair and RecF pathway recombination
NHY68_02385	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NHY68_02400	COG0681	Belongs to the peptidase S26 family
NHY68_02415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NHY68_02440	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NHY68_02445	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NHY68_02455	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NHY68_02465	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NHY68_02470	COG0583	DNA-binding transcription factor activity
NHY68_02475	COG4625	pathogenesis
NHY68_02490	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NHY68_02505	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NHY68_02515	COG1051	belongs to the nudix hydrolase family
NHY68_02515	COG1056	cytidyltransferase-related domain
NHY68_02520	COG1024	Enoyl-CoA hydratase
NHY68_02535	COG2814	Major facilitator Superfamily
NHY68_02560	COG1473	amidohydrolase
NHY68_02565	COG0824	Thioesterase
NHY68_02585	COG0823	Involved in the tonB-independent uptake of proteins
NHY68_02605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHY68_02640	COG0628	permease
NHY68_02650	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NHY68_02655	COG0596	Alpha beta hydrolase
NHY68_02660	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NHY68_02660	COG0616	signal peptide processing
NHY68_02670	COG2333	competence protein COMEC
NHY68_02670	COG0658	competence protein
NHY68_02675	COG1136	(ABC) transporter
NHY68_02715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NHY68_02735	COG0463	Glycosyl transferase, family 2
NHY68_02765	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NHY68_02770	COG1280	lysine exporter protein (LysE YggA)
NHY68_02780	COG0019	diaminopimelate decarboxylase activity
NHY68_02805	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
NHY68_02815	COG3339	Conserved Protein
NHY68_02820	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NHY68_02830	COG1929	Belongs to the glycerate kinase type-1 family
NHY68_02845	COG0778	Nitroreductase
NHY68_02890	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NHY68_02930	COG0584	glycerophosphoryl diester phosphodiesterase
NHY68_02960	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NHY68_02965	COG1597	lipid kinase activity
NHY68_02980	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NHY68_02985	COG0477	Major facilitator Superfamily
NHY68_03035	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NHY68_03065	COG0505	Belongs to the CarA family
NHY68_03085	COG0589	response to stress
NHY68_03100	COG2843	Capsule synthesis protein
NHY68_03120	COG2321	neutral zinc metallopeptidase
NHY68_03125	COG2354	Protein conserved in bacteria
NHY68_03145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NHY68_03170	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NHY68_03175	COG1053	succinate dehydrogenase
NHY68_03185	COG2009	succinate dehydrogenase
NHY68_03225	COG2921	Belongs to the UPF0250 family
NHY68_03230	COG0321	lipoyl(octanoyl) transferase activity
NHY68_03255	COG1733	regulation of RNA biosynthetic process
NHY68_03260	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NHY68_03265	COG1648	precorrin-2 dehydrogenase activity
NHY68_03265	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NHY68_03280	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NHY68_03325	COG1538	Outer membrane efflux protein
NHY68_03330	COG0393	Putative heavy-metal-binding
NHY68_03335	COG0393	Putative heavy-metal-binding
NHY68_03345	COG1028	Short-chain dehydrogenase reductase Sdr
NHY68_03355	COG0525	valine-tRNA ligase activity
NHY68_03375	COG0583	DNA-binding transcription factor activity
NHY68_03380	COG0004	ammonium transporteR
NHY68_03390	COG0642	Histidine kinase
NHY68_03395	COG0745	RESPONSE REGULATOR receiver
NHY68_03420	COG1752	Esterase of the alpha-beta hydrolase superfamily
NHY68_03435	COG2315	Protein conserved in bacteria
NHY68_03440	COG0142	geranyltranstransferase activity
NHY68_03445	COG2828	Protein conserved in bacteria
NHY68_03450	COG1113	amino acid transport
NHY68_03475	COG2207	Transcriptional regulator
NHY68_03500	COG2249	NAD(P)H dehydrogenase (quinone) activity
NHY68_03510	COG0560	Phosphoserine phosphatase
NHY68_03520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NHY68_03530	COG1530	ribonuclease E activity
NHY68_03535	COG0424	maF-like protein
NHY68_03540	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NHY68_03545	COG1792	Involved in formation and maintenance of cell shape
NHY68_03550	COG1077	Cell shape determining protein MreB Mrl
NHY68_03555	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHY68_03565	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHY68_03595	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
NHY68_03600	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NHY68_03605	COG1752	Esterase of the alpha-beta hydrolase superfamily
NHY68_03630	COG2814	Major facilitator Superfamily
NHY68_03690	COG2832	Protein of unknown function (DUF454)
NHY68_03700	COG5510	response to toxic substance
NHY68_03760	COG3422	double-strand break repair
NHY68_03765	COG2824	Alkylphosphonate utilization operon protein PhnA
NHY68_03780	COG0354	folic acid binding
NHY68_03785	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NHY68_03795	COG0679	Auxin Efflux Carrier
NHY68_03800	COG1902	pentaerythritol trinitrate reductase activity
NHY68_03820	COG2094	Belongs to the DNA glycosylase MPG family
NHY68_03845	COG1217	gtp-binding protein TYPA
NHY68_03850	COG2233	PERMEase
NHY68_03860	COG0833	amino acid
NHY68_03865	COG1690	Belongs to the RtcB family
NHY68_03875	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NHY68_03875	COG2885	chlorophyll binding
NHY68_03885	COG0183	Belongs to the thiolase family
NHY68_03905	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NHY68_03930	COG0183	Belongs to the thiolase family
NHY68_03960	COG1272	protein, Hemolysin III
NHY68_03965	COG0477	Major facilitator Superfamily
NHY68_03980	COG0450	alkyl hydroperoxide reductase
NHY68_04000	COG0285	dihydrofolate synthase activity
NHY68_04050	COG2096	Adenosyltransferase
NHY68_04070	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NHY68_04075	COG0745	RESPONSE REGULATOR receiver
NHY68_04080	COG2205	protein histidine kinase activity
NHY68_04090	COG1960	acyl-CoA dehydrogenase activity
NHY68_04095	COG1960	acyl-CoA dehydrogenase activity
NHY68_04100	COG0583	DNA-binding transcription factor activity
NHY68_04105	COG0625	glutathione transferase activity
NHY68_04170	COG0438	transferase activity, transferring glycosyl groups
NHY68_04175	COG0463	Glycosyl transferase, family 2
NHY68_04180	COG0726	polysaccharide deacetylase
NHY68_04255	COG1862	Preprotein translocase
NHY68_04265	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NHY68_04280	COG3781	membrane
NHY68_04285	COG0613	PHP domain protein
NHY68_04295	COG2350	Protein conserved in bacteria
NHY68_04325	COG1607	acyl-coa hydrolase
NHY68_04385	COG2199	diguanylate cyclase activity
NHY68_04395	COG1408	metallophosphoesterase
NHY68_04400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHY68_04410	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NHY68_04430	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NHY68_04435	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NHY68_04450	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NHY68_04460	COG2969	positive regulation of protein catabolic process
NHY68_04480	COG1960	acyl-CoA dehydrogenase activity
NHY68_04485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NHY68_04500	COG1309	transcriptional regulator
NHY68_04505	COG1960	acyl-CoA dehydrogenase activity
NHY68_04555	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NHY68_04585	COG1196	nuclear chromosome segregation
NHY68_04585	COG0741	lytic transglycosylase activity
NHY68_04585	COG0739	heme binding
NHY68_04595	COG1702	phosphate starvation-inducible protein PhoH
NHY68_04630	COG1295	ribonuclease BN
NHY68_04635	COG0697	spore germination
NHY68_04640	COG2169	Transcriptional regulator
NHY68_04645	COG0179	Fumarylacetoacetate (FAA) hydrolase
NHY68_04690	COG0557	exoribonuclease II activity
NHY68_04695	COG0339	signal peptide processing
NHY68_04700	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
NHY68_04730	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
NHY68_04735	COG1960	acyl-CoA dehydrogenase activity
NHY68_04895	COG0626	cystathionine gamma-synthase activity
NHY68_04905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NHY68_04905	COG1017	nitric oxide dioxygenase activity
NHY68_04910	COG1959	2 iron, 2 sulfur cluster binding
NHY68_04925	COG1301	dicarboxylic acid transport
NHY68_04930	COG1946	Acyl-CoA thioesterase
NHY68_04955	COG1040	competence protein
NHY68_04960	COG0494	nUDIX hydrolase
NHY68_04970	COG0598	Magnesium transport protein CorA
NHY68_04980	COG2854	intermembrane phospholipid transfer
NHY68_04990	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NHY68_04995	COG1127	ABC transporter
NHY68_05005	COG0513	Belongs to the DEAD box helicase family
NHY68_05025	COG0408	coproporphyrinogen oxidase activity
NHY68_05040	COG1960	acyl-CoA dehydrogenase activity
NHY68_05050	COG1983	PspC domain protein
NHY68_05055	COG0517	IMP dehydrogenase activity
NHY68_05140	COG1012	belongs to the aldehyde dehydrogenase family
NHY68_05150	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NHY68_05155	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NHY68_05190	COG1192	Involved in chromosome partitioning
NHY68_05195	COG0628	permease
NHY68_05205	COG1289	transmembrane transporter activity
NHY68_05225	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NHY68_05240	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NHY68_05265	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NHY68_05270	COG5380	lipid catabolic process
NHY68_05290	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NHY68_05340	COG0194	GDP metabolic process
NHY68_05355	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NHY68_05375	COG3307	-O-antigen
NHY68_05395	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
NHY68_05400	COG1704	LemA family
NHY68_05410	COG0493	'glutamate synthase
NHY68_05465	COG2226	methyltransferase
NHY68_05480	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NHY68_05530	COG0833	amino acid
NHY68_05620	COG2873	o-acetylhomoserine
NHY68_05625	COG4221	oxidoreductase activity
NHY68_05630	COG0659	secondary active sulfate transmembrane transporter activity
NHY68_05715	COG2329	Antibiotic biosynthesis monooxygenase
NHY68_05730	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NHY68_05800	COG2249	NAD(P)H dehydrogenase (quinone) activity
NHY68_05805	COG1733	regulation of RNA biosynthetic process
NHY68_05840	COG0667	Aldo Keto reductase
NHY68_05860	COG0583	DNA-binding transcription factor activity
NHY68_05865	COG2814	Major facilitator Superfamily
NHY68_05895	COG1335	isochorismatase
NHY68_05905	COG1012	belongs to the aldehyde dehydrogenase family
NHY68_05910	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NHY68_05920	COG1113	amino acid transport
NHY68_05945	COG2814	Major facilitator Superfamily
NHY68_05975	COG1309	transcriptional regulator
NHY68_05980	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NHY68_06010	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NHY68_06015	COG3162	membrane
NHY68_06050	COG1522	sequence-specific DNA binding
NHY68_06055	COG1335	isochorismatase
NHY68_06060	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NHY68_06070	COG0668	transmembrane transport
NHY68_06075	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NHY68_06080	COG1519	Transferase
NHY68_06085	COG1902	pentaerythritol trinitrate reductase activity
NHY68_06105	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NHY68_06130	COG0426	domain, Protein
NHY68_06130	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NHY68_06150	COG2119	membrane
NHY68_06160	COG0508	dehydrogenase complex catalyzes the overall conversion of
NHY68_06170	COG4942	peptidase
NHY68_06185	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NHY68_06195	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NHY68_06215	COG0189	ligase activity
NHY68_06235	COG0708	Exodeoxyribonuclease III
NHY68_06240	COG1393	Belongs to the ArsC family
NHY68_06290	COG2351	hydroxyisourate hydrolase activity
NHY68_06295	COG2233	PERMEase
NHY68_06305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NHY68_06315	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
NHY68_06320	COG1028	Short-chain dehydrogenase reductase Sdr
NHY68_06330	COG3150	esterase
NHY68_06360	COG2918	glutathione biosynthetic process
NHY68_06375	COG2733	membrane
NHY68_06380	COG0436	Aminotransferase
NHY68_06485	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NHY68_06490	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NHY68_06500	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NHY68_06505	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NHY68_06520	COG0010	Belongs to the arginase family
NHY68_06550	COG2188	Transcriptional regulator
NHY68_06560	COG0523	cobalamin synthesis protein
NHY68_06580	COG0625	glutathione transferase activity
NHY68_06600	COG1683	Conserved Protein
NHY68_06605	COG0534	Mate efflux family protein
NHY68_06610	COG0385	Bile acid
NHY68_06615	COG1335	isochorismatase
NHY68_06620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NHY68_06640	COG2116	formate transmembrane transporter activity
NHY68_06650	COG2133	pyrroloquinoline quinone binding
NHY68_06660	COG5487	UPF0391 membrane protein
NHY68_06675	COG1194	a g-specific adenine glycosylase
NHY68_06690	COG2818	Glycosylase
NHY68_06695	COG1064	alcohol dehydrogenase
NHY68_06715	COG0583	DNA-binding transcription factor activity
NHY68_06725	COG2814	Major facilitator Superfamily
NHY68_06775	COG2233	PERMEase
NHY68_06780	COG0583	DNA-binding transcription factor activity
NHY68_06815	COG0733	neurotransmitter:sodium symporter activity
NHY68_06855	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NHY68_06860	COG0657	acetylesterase activity
NHY68_06880	COG0583	DNA-binding transcription factor activity
NHY68_06910	COG2951	lytic endotransglycosylase activity
NHY68_06915	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NHY68_06930	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NHY68_06940	COG0671	phosphoesterase, PA-phosphatase related
NHY68_06945	COG0861	Integral membrane protein TerC family
NHY68_06980	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NHY68_06985	COG1230	cation diffusion facilitator family transporter
NHY68_07000	COG0706	membrane insertase activity
NHY68_07045	COG0586	Pfam SNARE associated Golgi protein
NHY68_07050	COG0488	(ABC) transporter
NHY68_07075	COG0596	Alpha beta hydrolase
NHY68_07080	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
NHY68_07085	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NHY68_07125	COG1047	Peptidyl-prolyl cis-trans
NHY68_07135	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NHY68_07140	COG0196	riboflavin kinase activity
NHY68_07150	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NHY68_07155	COG1309	transcriptional regulator
NHY68_07160	COG1116	anion transmembrane transporter activity
NHY68_07165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NHY68_07170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHY68_07175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NHY68_07200	COG1028	Short-chain dehydrogenase reductase Sdr
NHY68_07205	COG0546	phosphoglycolate phosphatase activity
NHY68_07270	COG3023	N-Acetylmuramoyl-L-alanine amidase
NHY68_07275	COG0728	peptidoglycan biosynthetic process
NHY68_07300	COG1596	polysaccharide export
NHY68_07305	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NHY68_07315	COG1215	transferase activity, transferring glycosyl groups
NHY68_07320	COG0438	transferase activity, transferring glycosyl groups
NHY68_07340	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NHY68_07345	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NHY68_07360	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NHY68_07370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NHY68_07380	COG2186	Transcriptional regulator
NHY68_07395	COG1448	Aminotransferase
NHY68_07405	COG1802	Transcriptional regulator
NHY68_07480	COG0564	pseudouridine synthase activity
NHY68_07520	COG0251	oxidation-reduction process
NHY68_07530	COG1113	amino acid transport
NHY68_07535	COG1113	amino acid transport
NHY68_07560	COG1960	acyl-CoA dehydrogenase activity
NHY68_07570	COG1024	Enoyl-CoA hydratase
NHY68_07575	COG0477	Major facilitator Superfamily
NHY68_07580	COG3916	Acyl-homoserine-lactone synthase
NHY68_07590	COG2197	response regulator
NHY68_07600	COG1960	acyl-CoA dehydrogenase activity
NHY68_07605	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NHY68_07605	COG3321	synthase
NHY68_07605	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NHY68_07605	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHY68_07645	COG0271	Belongs to the BolA IbaG family
NHY68_07670	COG0586	Pfam SNARE associated Golgi protein
NHY68_07675	COG2259	Doxx family
NHY68_07685	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NHY68_07685	COG0519	Catalyzes the synthesis of GMP from XMP
NHY68_07740	COG2837	iron assimilation
NHY68_07745	COG1280	lysine exporter protein (LysE YggA)
NHY68_07750	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NHY68_07755	COG1121	(ABC) transporter
NHY68_07820	COG0386	Belongs to the glutathione peroxidase family
NHY68_07835	COG1309	transcriptional regulator
NHY68_07840	COG0697	spore germination
NHY68_07850	COG0758	DNA mediated transformation
NHY68_07920	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NHY68_07930	COG0655	NAD(P)H dehydrogenase (quinone) activity
NHY68_07970	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHY68_07990	COG1253	flavin adenine dinucleotide binding
NHY68_08000	COG2860	membrane
NHY68_08005	COG0477	Major facilitator Superfamily
NHY68_08015	COG0318	PFAM AMP-dependent synthetase and ligase
NHY68_08030	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NHY68_08050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NHY68_08060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NHY68_08095	COG0589	response to stress
NHY68_08100	COG0659	secondary active sulfate transmembrane transporter activity
NHY68_08120	COG1061	Type III restriction enzyme res subunit
NHY68_08125	COG1002	Type II restriction enzyme, methylase subunits
NHY68_08160	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NHY68_08205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NHY68_08245	COG0589	response to stress
NHY68_08250	COG0659	secondary active sulfate transmembrane transporter activity
NHY68_08270	COG1061	Type III restriction enzyme res subunit
NHY68_08275	COG1002	Type II restriction enzyme, methylase subunits
NHY68_08340	COG0347	Belongs to the P(II) protein family
NHY68_08345	COG0004	ammonium transporteR
NHY68_08355	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NHY68_08355	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NHY68_08410	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NHY68_08415	COG0793	Belongs to the peptidase S41A family
NHY68_08430	COG2197	response regulator
NHY68_08455	COG4974	Belongs to the 'phage' integrase family
NHY68_08480	COG0772	Belongs to the SEDS family
NHY68_08485	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NHY68_08490	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NHY68_08495	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NHY68_08520	COG0697	spore germination
NHY68_08525	COG1538	Outer membrane efflux protein
NHY68_08545	COG3275	phosphorelay sensor kinase activity
NHY68_08555	COG0181	hydroxymethylbilane synthase activity
NHY68_08600	COG1716	ATPase activity
NHY68_08605	COG0546	phosphoglycolate phosphatase activity
NHY68_08700	COG0596	Alpha beta hydrolase
NHY68_08705	COG2056	Na+-H+ antiporter family
NHY68_08735	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NHY68_08800	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NHY68_08805	COG2169	Transcriptional regulator
NHY68_08805	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NHY68_08835	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NHY68_08860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHY68_08870	COG0237	dephospho-CoA kinase activity
NHY68_08875	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NHY68_08940	COG1320	monovalent cation:proton antiporter activity
NHY68_08945	COG2212	antiporter activity
NHY68_08950	COG1863	multisubunit Na H antiporter MnhE subunit
NHY68_08960	COG1006	Multisubunit Na H antiporter MnhC subunit
NHY68_08980	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NHY68_08985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NHY68_09000	COG2226	methyltransferase
NHY68_09025	COG1074	ATP-dependent DNA helicase activity
NHY68_09030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NHY68_09035	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NHY68_09050	COG0598	Magnesium transport protein CorA
NHY68_09060	COG0484	heat shock protein binding
NHY68_09070	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NHY68_09080	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NHY68_09105	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NHY68_09115	COG4535	Mg2 and Co2 transporter CorC
NHY68_09120	COG0425	Belongs to the sulfur carrier protein TusA family
NHY68_09125	COG0644	oxidoreductase
NHY68_09125	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
NHY68_09135	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NHY68_09150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NHY68_09155	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
NHY68_09195	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NHY68_09210	COG0534	Mate efflux family protein
NHY68_09220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NHY68_09225	COG4221	oxidoreductase activity
NHY68_09230	COG0583	DNA-binding transcription factor activity
NHY68_09245	COG0318	PFAM AMP-dependent synthetase and ligase
NHY68_09250	COG1530	ribonuclease E activity
NHY68_09260	COG0546	phosphoglycolate phosphatase activity
NHY68_09265	COG2378	regulation of single-species biofilm formation
NHY68_09270	COG0625	glutathione transferase activity
NHY68_09280	COG0583	DNA-binding transcription factor activity
NHY68_09345	COG0473	3-isopropylmalate dehydrogenase activity
NHY68_09400	COG1301	dicarboxylic acid transport
NHY68_09410	COG1560	Kdo2-lipid A biosynthetic process
NHY68_09415	COG1280	lysine exporter protein (LysE YggA)
NHY68_09420	COG0488	(ABC) transporter
NHY68_09425	COG2900	Belongs to the SlyX family
NHY68_09435	COG1733	regulation of RNA biosynthetic process
NHY68_09465	COG0724	RNA recognition motif
NHY68_09485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NHY68_09485	COG4651	solute:proton antiporter activity
NHY68_09510	COG0788	formyltetrahydrofolate deformylase activity
NHY68_09610	COG2813	Specifically methylates the guanine in position
NHY68_09610	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NHY68_09620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NHY68_09640	COG0740	serine-type endopeptidase activity
NHY68_09660	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
NHY68_09660	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
NHY68_09665	COG0280	phosphate acetyltransferase
NHY68_09665	COG0857	belongs to the CobB CobQ family
NHY68_09680	COG0800	Aldolase
NHY68_09695	COG3265	gluconokinase activity
NHY68_09700	COG1012	belongs to the aldehyde dehydrogenase family
NHY68_09710	COG2267	carboxylic ester hydrolase activity
NHY68_09725	COG0793	Belongs to the peptidase S41A family
NHY68_09760	COG1426	Protein conserved in bacteria
NHY68_09805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHY68_09815	COG0318	PFAM AMP-dependent synthetase and ligase
NHY68_09830	COG2986	histidine ammonia-lyase
NHY68_09870	COG1028	Short-chain dehydrogenase reductase Sdr
NHY68_09875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NHY68_09895	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NHY68_09905	COG1162	GTPase activity
NHY68_09910	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NHY68_09925	COG1538	Outer membrane efflux protein
NHY68_09930	COG0577	efflux transmembrane transporter activity
NHY68_09930	COG1136	(ABC) transporter
NHY68_09935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NHY68_09960	COG0028	Belongs to the TPP enzyme family
NHY68_09965	COG0440	acetolactate synthase activity
NHY68_09995	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NHY68_10010	COG0084	hydrolase, TatD family'
NHY68_10035	COG0583	DNA-binding transcription factor activity
NHY68_10050	COG2814	Major facilitator Superfamily
NHY68_10060	COG0697	spore germination
NHY68_10090	COG3622	Belongs to the hyi family
NHY68_10100	COG1024	Enoyl-CoA hydratase
NHY68_10105	COG2205	protein histidine kinase activity
NHY68_10105	COG5002	protein histidine kinase activity
NHY68_10105	COG0784	Response regulator, receiver
NHY68_10125	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NHY68_10135	COG3956	TIGRFAM MazG family protein
NHY68_10140	COG1555	photosystem II stabilization
NHY68_10145	COG0617	tRNA 3'-terminal CCA addition
NHY68_10150	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NHY68_10170	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NHY68_10175	COG3028	Belongs to the UPF0307 family
NHY68_10180	COG0318	PFAM AMP-dependent synthetase and ligase
NHY68_10195	COG0625	glutathione transferase activity
NHY68_10200	COG1238	metal cluster binding
NHY68_10245	COG0072	phenylalanine-tRNA ligase activity
NHY68_10275	COG0248	Ppx GppA phosphatase
NHY68_10285	COG0037	tRNA processing
NHY68_10325	COG1764	response to oxidative stress
NHY68_10330	COG1846	Transcriptional regulator
NHY68_10340	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NHY68_10405	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NHY68_10410	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NHY68_10420	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NHY68_10470	COG1214	PFAM Peptidase M22, glycoprotease
NHY68_10495	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NHY68_10500	COG0561	phosphatase activity
NHY68_10510	COG2132	Multicopper oxidase
NHY68_10515	COG3667	copper resistance
NHY68_10530	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NHY68_10535	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NHY68_10570	COG1063	alcohol dehydrogenase
NHY68_10575	COG0583	DNA-binding transcription factor activity
NHY68_10580	COG1960	acyl-CoA dehydrogenase activity
NHY68_10590	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NHY68_10600	COG1053	succinate dehydrogenase
NHY68_10605	COG0583	DNA-binding transcription factor activity
NHY68_10665	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NHY68_10715	COG4993	Dehydrogenase
NHY68_10785	COG2205	protein histidine kinase activity
NHY68_10795	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHY68_10815	COG0745	RESPONSE REGULATOR receiver
NHY68_10855	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NHY68_10885	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NHY68_10890	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NHY68_10910	COG0583	DNA-binding transcription factor activity
NHY68_10930	COG0668	transmembrane transport
NHY68_10940	COG2081	HI0933 family
NHY68_10945	COG2515	1-aminocyclopropane-1-carboxylate deaminase
NHY68_10975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NHY68_10975	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NHY68_10985	COG0489	protein tyrosine kinase activity
NHY68_11035	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NHY68_11060	COG0730	response to heat
NHY68_11070	COG1196	nuclear chromosome segregation
NHY68_11090	COG2223	nitrite transmembrane transporter activity
NHY68_11095	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
NHY68_11105	COG0596	Alpha beta hydrolase
NHY68_11105	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NHY68_11105	COG2226	methyltransferase
NHY68_11120	COG4106	trans-aconitate 2-methyltransferase activity
NHY68_11140	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NHY68_11145	COG0009	L-threonylcarbamoyladenylate synthase
NHY68_11150	COG3101	peptidyl-lysine hydroxylation
NHY68_11155	COG1399	metal-binding, possibly nucleic acid-binding protein
NHY68_11180	COG1652	LysM domain
NHY68_11185	COG0351	phosphomethylpyrimidine kinase
NHY68_11185	COG0352	thiamine-phosphate diphosphorylase activity
NHY68_11185	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NHY68_11195	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NHY68_11225	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHY68_11255	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NHY68_11270	COG0358	DNA primase activity
NHY68_11280	COG0564	pseudouridine synthase activity
NHY68_11305	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NHY68_11325	COG0583	DNA-binding transcription factor activity
NHY68_11330	COG0473	3-isopropylmalate dehydrogenase activity
NHY68_11350	COG1012	belongs to the aldehyde dehydrogenase family
NHY68_11370	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NHY68_11370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NHY68_11385	COG1981	membrane
NHY68_11430	COG0456	acetyltransferase
NHY68_11440	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NHY68_11450	COG1674	ftsk spoiiie
NHY68_11450	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NHY68_11455	COG1280	lysine exporter protein (LysE YggA)
NHY68_11480	COG2894	cell division
NHY68_11495	COG0204	Acyl-transferase
NHY68_11500	COG2885	chlorophyll binding
NHY68_11505	COG0210	DNA helicase
NHY68_11515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NHY68_11530	COG0121	glutamine amidotransferase
NHY68_11550	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NHY68_11555	COG0735	belongs to the Fur family
NHY68_11580	COG0420	3'-5' exonuclease activity
NHY68_11600	COG1090	epimerase
NHY68_11615	COG2050	protein possibly involved in aromatic compounds catabolism
NHY68_11625	COG2814	Major facilitator Superfamily
NHY68_11665	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NHY68_11785	COG1484	DNA-dependent DNA replication
NHY68_12010	COG2026	Addiction module toxin, RelE StbE family
NHY68_12135	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHY68_12190	COG0477	Major facilitator Superfamily
NHY68_12195	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NHY68_12220	COG0531	amino acid
NHY68_12225	COG2040	homocysteine
NHY68_12250	COG1309	transcriptional regulator
NHY68_12255	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NHY68_12270	COG1607	acyl-coa hydrolase
NHY68_12280	COG0523	cobalamin synthesis protein
NHY68_12300	COG0726	polysaccharide deacetylase
NHY68_12300	COG1649	PFAM Uncharacterised BCR, COG1649
NHY68_12305	COG1215	transferase activity, transferring glycosyl groups
NHY68_12315	COG1024	Enoyl-CoA hydratase
NHY68_12330	COG1414	Transcriptional regulator
NHY68_12350	COG1028	Short-chain dehydrogenase reductase Sdr
NHY68_12360	COG0446	pyridine nucleotide-disulphide oxidoreductase
NHY68_12365	COG2271	Major facilitator Superfamily
NHY68_12375	COG2267	carboxylic ester hydrolase activity
NHY68_12380	COG1028	Short-chain dehydrogenase reductase Sdr
NHY68_12395	COG0028	Belongs to the TPP enzyme family
NHY68_12405	COG0477	Major facilitator Superfamily
NHY68_12410	COG0242	peptide deformylase activity
NHY68_12420	COG2207	Transcriptional regulator
NHY68_12425	COG2223	nitrite transmembrane transporter activity
NHY68_12440	COG0583	DNA-binding transcription factor activity
NHY68_12445	COG1028	Short-chain dehydrogenase reductase Sdr
NHY68_12450	COG2271	Major facilitator Superfamily
NHY68_12455	COG3959	Transketolase, thiamine diphosphate binding domain
NHY68_12460	COG3958	Transketolase
NHY68_12490	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NHY68_12535	COG4181	ATPase activity
NHY68_12540	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
NHY68_12565	COG0583	DNA-binding transcription factor activity
NHY68_12575	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NHY68_12580	COG1773	rubredoxin
NHY68_12635	COG1253	flavin adenine dinucleotide binding
NHY68_12685	COG0830	nickel cation binding
NHY68_12705	COG0768	penicillin binding
NHY68_12730	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NHY68_12735	COG2878	Part of a membrane complex involved in electron transport
NHY68_12740	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NHY68_12750	COG3384	dioxygenase
NHY68_12785	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NHY68_13110	COG0739	heme binding
NHY68_13195	COG0006	proline dipeptidase activity
NHY68_13200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NHY68_13225	COG1279	arginine transmembrane transporter activity
NHY68_13305	COG0488	(ABC) transporter
NHY68_13310	COG3173	Aminoglycoside phosphotransferase
NHY68_13320	COG2433	Pfam Transposase IS66
NHY68_13370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NHY68_13375	COG2011	ABC-type metal ion transport system permease component
NHY68_13380	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NHY68_13385	COG1464	Belongs to the NlpA lipoprotein family
NHY68_13390	COG0151	Belongs to the GarS family
NHY68_13395	COG0138	bifunctional purine biosynthesis protein purh
NHY68_13400	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NHY68_13430	COG2308	Evidence 4 Homologs of previously reported genes of
NHY68_13440	COG1305	Transglutaminase-like
NHY68_13450	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NHY68_13455	COG0305	Participates in initiation and elongation during chromosome replication
NHY68_13480	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NHY68_13490	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NHY68_13520	COG0726	polysaccharide deacetylase
NHY68_13520	COG1649	PFAM Uncharacterised BCR, COG1649
NHY68_13525	COG1215	transferase activity, transferring glycosyl groups
NHY68_13530	COG3658	cytochrome
NHY68_13540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHY68_13580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NHY68_13605	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NHY68_13635	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NHY68_13650	COG0745	RESPONSE REGULATOR receiver
NHY68_13655	COG0174	glutamine synthetase
NHY68_13675	COG0729	surface antigen
NHY68_13700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NHY68_13705	COG2814	Major facilitator Superfamily
NHY68_13720	COG0583	DNA-binding transcription factor activity
NHY68_13735	COG1187	pseudouridine synthase activity
NHY68_13755	COG0802	atpase or kinase
NHY68_13760	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NHY68_13770	COG1923	regulation of RNA biosynthetic process
NHY68_13775	COG0697	spore germination
NHY68_13790	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NHY68_13800	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NHY68_13810	COG4302	ethanolamine ammonia-lyase activity
NHY68_13820	COG0531	amino acid
NHY68_13845	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NHY68_13855	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
NHY68_13875	COG0308	aminopeptidase N
NHY68_13885	COG4221	oxidoreductase activity
NHY68_13895	COG1605	Chorismate mutase
NHY68_13910	COG1309	transcriptional regulator
NHY68_13920	COG0668	transmembrane transport
NHY68_13975	COG0488	(ABC) transporter
NHY68_13980	COG0589	response to stress
NHY68_14020	COG1522	sequence-specific DNA binding
NHY68_14030	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NHY68_14035	COG0583	DNA-binding transcription factor activity
NHY68_14055	COG2030	dehydratase
NHY68_14060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NHY68_14075	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHY68_14085	COG0824	Thioesterase
NHY68_14100	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NHY68_14120	COG0069	glutamate synthase activity
NHY68_14155	COG0511	ligase activity, forming carbon-carbon bonds
NHY68_14175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NHY68_14175	COG1116	anion transmembrane transporter activity
NHY68_14180	COG0745	RESPONSE REGULATOR receiver
NHY68_14195	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NHY68_14200	COG0243	molybdopterin cofactor binding
NHY68_14230	COG0521	Mo-molybdopterin cofactor biosynthetic process
NHY68_14230	COG0315	cyclic pyranopterin monophosphate synthase activity
NHY68_14235	COG0303	'Molybdopterin
NHY68_14245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NHY68_14270	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
NHY68_14330	COG2204	response regulator
NHY68_14335	COG3852	Histidine kinase
NHY68_14355	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NHY68_14360	COG0575	Belongs to the CDS family
NHY68_14410	COG2137	regulation of response to DNA damage stimulus
NHY68_14420	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NHY68_14425	COG1011	Hydrolase
NHY68_14450	COG1522	sequence-specific DNA binding
NHY68_14485	COG2135	peptidase activity
NHY68_14500	COG3300	MHYT domain
NHY68_14500	COG5001	Diguanylate cyclase
NHY68_14520	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NHY68_14520	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NHY68_14520	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
NHY68_14535	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NHY68_14535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NHY68_14570	COG0024	Methionine aminopeptidase
NHY68_14575	COG0583	DNA-binding transcription factor activity
NHY68_14585	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NHY68_14590	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NHY68_14595	COG0517	IMP dehydrogenase activity
NHY68_14595	COG0516	GMP reductase activity
NHY68_14630	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
NHY68_14645	COG4890	Cyd operon protein YbgT
NHY68_14650	COG1294	oxidase, subunit
NHY68_14665	COG1585	Membrane protein implicated in regulation of membrane protease activity
NHY68_14675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NHY68_14695	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NHY68_14700	COG0569	domain protein
NHY68_14705	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NHY68_14730	COG1765	OsmC-like protein
NHY68_14765	COG0542	response to heat
NHY68_14840	COG2323	membrane
NHY68_14845	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NHY68_14855	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NHY68_14860	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NHY68_14865	COG0183	Belongs to the thiolase family
NHY68_14870	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NHY68_14875	COG0596	Alpha beta hydrolase
NHY68_14880	COG2271	Major facilitator Superfamily
NHY68_14885	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NHY68_14895	COG3485	protocatechuate 3,4-dioxygenase
NHY68_14900	COG0710	3-dehydroquinate dehydratase activity
NHY68_14905	COG3420	alginic acid biosynthetic process
NHY68_14915	COG4993	Dehydrogenase
NHY68_14925	COG2391	methyltransferase activity
NHY68_14940	COG1414	Transcriptional regulator
NHY68_14950	COG1960	acyl-CoA dehydrogenase activity
NHY68_14975	COG2814	Major facilitator Superfamily
NHY68_14985	COG0154	amidase activity
NHY68_15005	COG4638	Rieske (2fe-2S)
NHY68_15015	COG1028	Short-chain dehydrogenase reductase Sdr
NHY68_15025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NHY68_15035	COG3733	amine oxidase
NHY68_15045	COG1012	belongs to the aldehyde dehydrogenase family
NHY68_15055	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NHY68_15060	COG0183	Belongs to the thiolase family
NHY68_15065	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NHY68_15070	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NHY68_15080	COG4829	muconolactone delta-isomerase
NHY68_15085	COG4948	Mandelate Racemase Muconate Lactonizing
NHY68_15100	COG2186	Transcriptional regulator
NHY68_15120	COG1012	belongs to the aldehyde dehydrogenase family
NHY68_15140	COG1960	acyl-CoA dehydrogenase activity
NHY68_15150	COG3829	transcription factor binding
NHY68_15160	COG3162	membrane
NHY68_15175	COG1012	belongs to the aldehyde dehydrogenase family
NHY68_15210	COG1846	Transcriptional regulator
NHY68_15225	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NHY68_15255	COG1309	transcriptional regulator
NHY68_15265	COG1335	isochorismatase
NHY68_15270	COG0583	DNA-binding transcription factor activity
NHY68_15290	COG1473	amidohydrolase
NHY68_15350	COG0583	DNA-binding transcription factor activity
NHY68_15380	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NHY68_15410	COG1566	PFAM secretion protein HlyD family protein
NHY68_15440	COG0583	DNA-binding transcription factor activity
NHY68_15445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NHY68_15455	COG2084	Dehydrogenase
NHY68_15485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHY68_15510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHY68_15635	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NHY68_15710	COG2205	protein histidine kinase activity
NHY68_15715	COG0745	RESPONSE REGULATOR receiver
NHY68_15720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NHY68_15725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NHY68_15760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NHY68_15780	COG3539	Fimbrial protein
NHY68_15810	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
NHY68_15820	COG0753	catalase activity
NHY68_15835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHY68_15895	COG3433	isochorismatase activity
NHY68_15895	COG1535	isochorismatase
NHY68_15900	COG1028	Short-chain dehydrogenase reductase Sdr
NHY68_15905	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NHY68_15910	COG4149	molybdate abc transporter
NHY68_15915	COG0725	ABC transporter, periplasmic molybdate-binding protein
NHY68_15930	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
NHY68_15935	COG0543	2 iron, 2 sulfur cluster binding
NHY68_15935	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NHY68_15960	COG1028	Short-chain dehydrogenase reductase Sdr
NHY68_15985	COG1028	Short-chain dehydrogenase reductase Sdr
NHY68_15990	COG2610	gluconate transmembrane transporter activity
NHY68_16000	COG0583	DNA-binding transcription factor activity
NHY68_16010	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NHY68_16015	COG2031	fatty acid transporter
NHY68_16020	COG0183	Belongs to the thiolase family
NHY68_16025	COG0583	DNA-binding transcription factor activity
NHY68_16030	COG0583	DNA-binding transcription factor activity
NHY68_16055	COG0477	Major facilitator Superfamily
NHY68_16080	COG4521	taurine ABC transporter
NHY68_16095	COG2188	Transcriptional regulator
NHY68_16105	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NHY68_16110	COG1733	regulation of RNA biosynthetic process
NHY68_16115	COG2207	Transcriptional regulator
NHY68_16115	COG3708	Transcriptional regulator
NHY68_16130	COG0730	response to heat
NHY68_16155	COG3781	membrane
NHY68_16170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NHY68_16175	COG0508	dehydrogenase complex catalyzes the overall conversion of
NHY68_16180	COG0022	dehydrogenase e1 component
NHY68_16185	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NHY68_16190	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NHY68_16205	COG3706	GGDEF domain
NHY68_16220	COG0133	tryptophan synthase activity
NHY68_16230	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NHY68_16265	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NHY68_16290	COG2226	methyltransferase
NHY68_16345	COG0842	Transport permease protein
NHY68_16350	COG0842	Transport permease protein
NHY68_16370	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NHY68_16375	COG4773	Receptor
NHY68_16395	COG0730	response to heat
NHY68_16400	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NHY68_16420	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NHY68_16475	COG4264	IucA IucC family
NHY68_16480	COG4264	IucA IucC family
NHY68_16500	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NHY68_16515	COG1960	acyl-CoA dehydrogenase activity
NHY68_16520	COG1960	acyl-CoA dehydrogenase activity
NHY68_16530	COG2207	Transcriptional regulator
NHY68_16535	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NHY68_16540	COG0776	regulation of translation
NHY68_16565	COG0822	iron-sulfur transferase activity
NHY68_16570	COG0316	Belongs to the HesB IscA family
NHY68_16600	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NHY68_16620	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NHY68_16625	COG0702	epimerase
NHY68_16660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHY68_16670	COG0339	signal peptide processing
NHY68_16755	COG0776	regulation of translation
NHY68_16820	COG0084	hydrolase, TatD family'
NHY68_16840	COG1663	tetraacyldisaccharide 4'-kinase activity
NHY68_16845	COG1132	(ABC) transporter
NHY68_16855	COG0811	peptide transport
NHY68_16860	COG1475	DNA binding
NHY68_16865	COG1192	Involved in chromosome partitioning
NHY68_16875	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NHY68_16890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NHY68_16895	COG0191	fructose-bisphosphate aldolase activity
NHY68_16915	COG0424	maF-like protein
NHY68_16920	COG2850	peptidyl-arginine hydroxylation
NHY68_16930	COG0640	Transcriptional regulator
NHY68_16945	COG3122	Protein conserved in bacteria
NHY68_16970	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NHY68_16975	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NHY68_16990	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NHY68_17005	COG3698	Phosphodiester glycosidase
NHY68_17015	COG2353	YceI-like domain
NHY68_17025	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NHY68_17070	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NHY68_17070	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NHY68_17095	COG3539	Fimbrial protein
NHY68_17100	COG3121	Chaperone
NHY68_17125	COG0697	spore germination
NHY68_17135	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NHY68_17145	COG0583	DNA-binding transcription factor activity
NHY68_17165	COG1309	transcriptional regulator
NHY68_17180	COG1522	sequence-specific DNA binding
NHY68_17190	COG1126	abc transporter atp-binding protein
NHY68_17195	COG0765	amino acid transport
NHY68_17200	COG0765	amino acid transport
NHY68_17230	COG1464	Belongs to the NlpA lipoprotein family
NHY68_17240	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NHY68_17245	COG2011	ABC-type metal ion transport system permease component
NHY68_17250	COG0012	GTP binding
NHY68_17275	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NHY68_17315	COG0386	Belongs to the glutathione peroxidase family
NHY68_17365	COG3634	alkyl hydroperoxide reductase activity
NHY68_17380	COG0583	DNA-binding transcription factor activity
NHY68_17385	COG0798	PFAM Bile acid sodium symporter
NHY68_17390	COG0640	Transcriptional regulator
NHY68_17415	COG0583	DNA-binding transcription factor activity
NHY68_17425	COG1953	Uracil, thiamine, allantoin
NHY68_17435	COG2175	clavaminate synthase activity
NHY68_17440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NHY68_17445	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NHY68_17450	COG4521	taurine ABC transporter
NHY68_17460	COG0477	Major facilitator Superfamily
NHY68_17480	COG1271	oxidase subunit
NHY68_17485	COG1294	oxidase, subunit
NHY68_17495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NHY68_17515	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NHY68_17535	COG3052	prosthetic group binding
NHY68_17540	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
NHY68_17550	COG2814	Major facilitator Superfamily
NHY68_17570	COG1346	cytolysis
NHY68_17580	COG0583	DNA-binding transcription factor activity
NHY68_17585	COG0625	glutathione transferase activity
NHY68_17590	COG0625	glutathione transferase activity
NHY68_17610	COG1045	serine acetyltransferase
NHY68_17615	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NHY68_17620	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NHY68_17630	COG1280	lysine exporter protein (LysE YggA)
NHY68_17645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NHY68_17650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NHY68_17655	COG1126	abc transporter atp-binding protein
NHY68_17660	COG0765	amino acid transport
NHY68_17705	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NHY68_17730	COG1028	Short-chain dehydrogenase reductase Sdr
NHY68_17780	COG0583	DNA-binding transcription factor activity
NHY68_17800	COG0318	PFAM AMP-dependent synthetase and ligase
NHY68_17805	COG1309	transcriptional regulator
NHY68_17810	COG1960	acyl-CoA dehydrogenase activity
NHY68_17815	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NHY68_17820	COG1024	Enoyl-CoA hydratase
NHY68_17825	COG4770	biotin carboxylase activity
NHY68_17850	COG1960	acyl-CoA dehydrogenase activity
NHY68_17860	COG2814	Major facilitator Superfamily
NHY68_17870	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NHY68_17875	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NHY68_17880	COG2814	Major facilitator Superfamily
NHY68_17885	COG1960	acyl-CoA dehydrogenase activity
NHY68_17890	COG1024	Enoyl-CoA hydratase
NHY68_17895	COG1028	Short-chain dehydrogenase reductase Sdr
NHY68_17900	COG1250	3-hydroxyacyl-CoA dehydrogenase
NHY68_17905	COG0183	Belongs to the thiolase family
NHY68_17915	COG2814	Major facilitator Superfamily
NHY68_17940	COG1960	acyl-CoA dehydrogenase activity
NHY68_17950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NHY68_17955	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NHY68_17970	COG3842	ATPase activity
NHY68_17975	COG1840	ABC-type Fe3 transport system, periplasmic component
NHY68_17985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NHY68_17990	COG1414	Transcriptional regulator
NHY68_18000	COG0583	DNA-binding transcription factor activity
NHY68_18005	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NHY68_18010	COG1012	belongs to the aldehyde dehydrogenase family
NHY68_18020	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NHY68_18030	COG1012	belongs to the aldehyde dehydrogenase family
NHY68_18035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHY68_18040	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NHY68_18065	COG3038	cytochrome b561
NHY68_18070	COG0753	catalase activity
NHY68_18105	COG2050	protein possibly involved in aromatic compounds catabolism
NHY68_18115	COG3327	negative regulation of DNA-templated transcription, initiation
NHY68_18120	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NHY68_18125	COG0183	Belongs to the thiolase family
NHY68_18135	COG1024	Enoyl-CoA hydratase
NHY68_18140	COG1024	Enoyl-CoA hydratase
NHY68_18145	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NHY68_18150	COG2151	metal-sulfur cluster biosynthetic enzyme
NHY68_18155	COG3396	Phenylacetate-CoA oxygenase
NHY68_18160	COG3460	Phenylacetate-CoA oxygenase
NHY68_18165	COG3396	Phenylacetate-CoA oxygenase
NHY68_18170	COG2030	dehydratase
NHY68_18170	COG1012	belongs to the aldehyde dehydrogenase family
NHY68_18185	COG1012	belongs to the aldehyde dehydrogenase family
NHY68_18200	COG0446	pyridine nucleotide-disulphide oxidoreductase
NHY68_18230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NHY68_18240	COG0789	Transcriptional regulator
NHY68_18255	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NHY68_18270	COG2807	transmembrane transport
NHY68_18275	COG0590	tRNA wobble adenosine to inosine editing
NHY68_18395	COG1116	anion transmembrane transporter activity
NHY68_18405	COG2249	NAD(P)H dehydrogenase (quinone) activity
NHY68_18425	COG1063	alcohol dehydrogenase
NHY68_18435	COG1309	transcriptional regulator
NHY68_18460	COG4770	biotin carboxylase activity
NHY68_18480	COG1914	H( )-stimulated, divalent metal cation uptake system
NHY68_18485	COG0583	DNA-binding transcription factor activity