locus-tag	class	description
AB237_0004	COG0592	DNA-directed DNA polymerase activity
AB237_0006	COG0187	DNA topoisomerase II activity
AB237_0008	COG0586	Pfam SNARE associated Golgi protein
AB237_0009	COG0488	(ABC) transporter
AB237_0014	COG0596	Alpha beta hydrolase
AB237_0015	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AB237_0016	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AB237_0028	COG0733	neurotransmitter:sodium symporter activity
AB237_0033	COG0583	DNA-binding transcription factor activity
AB237_0034	COG2233	PERMEase
AB237_0037	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AB237_0044	COG2814	Major facilitator Superfamily
AB237_0045	COG0583	DNA-binding transcription factor activity
AB237_0046	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AB237_0047	COG1064	alcohol dehydrogenase
AB237_0048	COG2818	Glycosylase
AB237_0050	COG1194	a g-specific adenine glycosylase
AB237_0053	COG2983	Belongs to the UPF0260 family
AB237_0054	COG2133	pyrroloquinoline quinone binding
AB237_0055	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AB237_0056	COG2116	formate transmembrane transporter activity
AB237_0059	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AB237_0060	COG1335	isochorismatase
AB237_0061	COG0385	Bile acid
AB237_0062	COG0534	Mate efflux family protein
AB237_0063	COG1683	Conserved Protein
AB237_0066	COG0625	glutathione transferase activity
AB237_0068	COG1113	amino acid transport
AB237_0070	COG0523	cobalamin synthesis protein
AB237_0072	COG2188	Transcriptional regulator
AB237_0078	COG0546	phosphoglycolate phosphatase activity
AB237_0079	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AB237_0085	COG3121	Chaperone
AB237_0086	COG3188	usher protein
AB237_0091	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AB237_0093	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AB237_0102	COG0753	catalase activity
AB237_0109	COG2826	transposase and inactivated derivatives, IS30 family
AB237_0115	COG0534	Mate efflux family protein
AB237_0116	COG0436	Aminotransferase
AB237_0117	COG2733	membrane
AB237_0120	COG2918	glutathione biosynthetic process
AB237_0122	COG3501	Rhs element vgr protein
AB237_0123	COG3179	chitinase
AB237_0128	COG3150	esterase
AB237_0130	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AB237_0132	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB237_0134	COG2233	PERMEase
AB237_0144	COG1393	Belongs to the ArsC family
AB237_0145	COG0708	Exodeoxyribonuclease III
AB237_0147	COG0189	ligase activity
AB237_0151	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AB237_0153	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AB237_0156	COG4942	peptidase
AB237_0158	COG0508	dehydrogenase complex catalyzes the overall conversion of
AB237_0159	COG2119	membrane
AB237_0160	COG4774	siderophore transport
AB237_0161	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AB237_0161	COG0426	domain, Protein
AB237_0165	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AB237_0169	COG1902	pentaerythritol trinitrate reductase activity
AB237_0170	COG1519	Transferase
AB237_0171	COG0668	transmembrane transport
AB237_0173	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AB237_0174	COG1335	isochorismatase
AB237_0175	COG1522	sequence-specific DNA binding
AB237_0180	COG0784	Response regulator, receiver
AB237_0180	COG2198	Histidine kinase
AB237_0180	COG2205	protein histidine kinase activity
AB237_0181	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AB237_0183	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AB237_0185	COG3706	GGDEF domain
AB237_0186	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AB237_0187	COG1309	transcriptional regulator
AB237_0191	COG0351	phosphomethylpyrimidine kinase
AB237_0191	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AB237_0191	COG0352	thiamine-phosphate diphosphorylase activity
AB237_0193	COG2814	Major facilitator Superfamily
AB237_0195	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AB237_0197	COG1113	amino acid transport
AB237_0199	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AB237_0200	COG1012	belongs to the aldehyde dehydrogenase family
AB237_0202	COG1335	isochorismatase
AB237_0207	COG2814	Major facilitator Superfamily
AB237_0208	COG0583	DNA-binding transcription factor activity
AB237_0211	COG0667	Aldo Keto reductase
AB237_0215	COG1733	regulation of RNA biosynthetic process
AB237_0217	COG1733	regulation of RNA biosynthetic process
AB237_0218	COG2249	NAD(P)H dehydrogenase (quinone) activity
AB237_0221	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AB237_0222	COG2207	Transcriptional regulator
AB237_0232	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AB237_0240	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AB237_0246	COG0427	acetyl-CoA hydrolase
AB237_0248	COG0745	RESPONSE REGULATOR receiver
AB237_0250	COG0659	secondary active sulfate transmembrane transporter activity
AB237_0251	COG4221	oxidoreductase activity
AB237_0253	COG0488	(ABC) transporter
AB237_0265	COG0833	amino acid
AB237_0274	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AB237_0275	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AB237_0278	COG2226	methyltransferase
AB237_0288	COG0067	glutamate synthase
AB237_0288	COG0069	glutamate synthase activity
AB237_0288	COG0070	glutamate synthase
AB237_0289	COG0493	'glutamate synthase
AB237_0291	COG1704	LemA family
AB237_0292	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AB237_0294	COG3307	-O-antigen
AB237_0299	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AB237_0301	COG0194	GDP metabolic process
AB237_0308	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AB237_0312	COG5380	lipid catabolic process
AB237_0313	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AB237_0318	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AB237_0319	COG0277	FAD linked oxidase domain protein
AB237_0321	COG2249	NAD(P)H dehydrogenase (quinone) activity
AB237_0324	COG1289	transmembrane transporter activity
AB237_0325	COG2032	superoxide dismutase activity
AB237_0326	COG2826	transposase and inactivated derivatives, IS30 family
AB237_0327	COG0628	permease
AB237_0328	COG1192	Involved in chromosome partitioning
AB237_0334	COG0833	amino acid
AB237_0335	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AB237_0336	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AB237_0338	COG1012	belongs to the aldehyde dehydrogenase family
AB237_0346	COG0583	DNA-binding transcription factor activity
AB237_0354	COG0517	IMP dehydrogenase activity
AB237_0356	COG1960	acyl-CoA dehydrogenase activity
AB237_0359	COG0408	coproporphyrinogen oxidase activity
AB237_0363	COG0513	Belongs to the DEAD box helicase family
AB237_0364	COG1127	ABC transporter
AB237_0365	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AB237_0367	COG2854	intermembrane phospholipid transfer
AB237_0368	COG0598	Magnesium transport protein CorA
AB237_0370	COG0494	nUDIX hydrolase
AB237_0371	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AB237_0375	COG1946	Acyl-CoA thioesterase
AB237_0376	COG1301	dicarboxylic acid transport
AB237_0379	COG1959	2 iron, 2 sulfur cluster binding
AB237_0380	COG1017	nitric oxide dioxygenase activity
AB237_0380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AB237_0381	COG0433	COG0433 Predicted ATPase
AB237_0382	COG0626	cystathionine gamma-synthase activity
AB237_0402	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AB237_0407	COG1960	acyl-CoA dehydrogenase activity
AB237_0413	COG0339	signal peptide processing
AB237_0414	COG0557	exoribonuclease II activity
AB237_0423	COG0179	Fumarylacetoacetate (FAA) hydrolase
AB237_0424	COG2169	Transcriptional regulator
AB237_0425	COG0697	spore germination
AB237_0426	COG1295	ribonuclease BN
AB237_0433	COG1702	phosphate starvation-inducible protein PhoH
AB237_0435	COG0741	lytic transglycosylase activity
AB237_0435	COG1196	nuclear chromosome segregation
AB237_0435	COG0739	heme binding
AB237_0441	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AB237_0442	COG1183	phosphatidylcholine synthase activity
AB237_0455	COG1960	acyl-CoA dehydrogenase activity
AB237_0456	COG1309	transcriptional regulator
AB237_0459	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AB237_0460	COG1960	acyl-CoA dehydrogenase activity
AB237_0464	COG2969	positive regulation of protein catabolic process
AB237_0466	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AB237_0469	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AB237_0470	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AB237_0473	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AB237_0475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AB237_0476	COG1408	metallophosphoesterase
AB237_0478	COG2199	diguanylate cyclase activity
AB237_0479	COG2826	transposase and inactivated derivatives, IS30 family
AB237_0492	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AB237_0492	COG3453	Protein conserved in bacteria
AB237_0495	COG1607	acyl-coa hydrolase
AB237_0500	COG0613	PHP domain protein
AB237_0501	COG3781	membrane
AB237_0503	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AB237_0504	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AB237_0506	COG1862	Preprotein translocase
AB237_0512	COG2205	protein histidine kinase activity
AB237_0513	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AB237_0517	COG0463	Glycosyl transferase, family 2
AB237_0518	COG0438	transferase activity, transferring glycosyl groups
AB237_0529	COG0625	glutathione transferase activity
AB237_0530	COG0583	DNA-binding transcription factor activity
AB237_0531	COG1960	acyl-CoA dehydrogenase activity
AB237_0532	COG1960	acyl-CoA dehydrogenase activity
AB237_0534	COG2205	protein histidine kinase activity
AB237_0535	COG0745	RESPONSE REGULATOR receiver
AB237_0536	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AB237_0540	COG2096	Adenosyltransferase
AB237_0543	COG0133	tryptophan synthase activity
AB237_0549	COG0285	dihydrofolate synthase activity
AB237_0553	COG0450	alkyl hydroperoxide reductase
AB237_0556	COG0477	Major facilitator Superfamily
AB237_0557	COG1272	protein, Hemolysin III
AB237_0562	COG0183	Belongs to the thiolase family
AB237_0563	COG2207	Transcriptional regulator
AB237_0567	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AB237_0570	COG0183	Belongs to the thiolase family
AB237_0572	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AB237_0572	COG2885	chlorophyll binding
AB237_0573	COG1690	Belongs to the RtcB family
AB237_0574	COG0833	amino acid
AB237_0576	COG2233	PERMEase
AB237_0581	COG2094	Belongs to the DNA glycosylase MPG family
AB237_0582	COG4772	TonB-dependent receptor
AB237_0585	COG4772	TonB-dependent receptor
AB237_0586	COG1902	pentaerythritol trinitrate reductase activity
AB237_0587	COG0679	Auxin Efflux Carrier
AB237_0589	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AB237_0590	COG0354	folic acid binding
AB237_0592	COG3189	MarR family transcriptional regulator
AB237_0593	COG2824	Alkylphosphonate utilization operon protein PhnA
AB237_0594	COG3422	double-strand break repair
AB237_0602	COG0840	transmembrane signaling receptor activity
AB237_0606	COG2832	Protein of unknown function (DUF454)
AB237_0607	COG1376	ErfK ybiS ycfS ynhG family protein
AB237_0618	COG1289	transmembrane transporter activity
AB237_0619	COG2814	Major facilitator Superfamily
AB237_0622	COG1115	amino acid carrier protein
AB237_0623	COG1752	Esterase of the alpha-beta hydrolase superfamily
AB237_0624	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AB237_0625	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AB237_0631	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AB237_0633	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AB237_0634	COG1077	Cell shape determining protein MreB Mrl
AB237_0635	COG1792	Involved in formation and maintenance of cell shape
AB237_0637	COG0424	maF-like protein
AB237_0638	COG1530	ribonuclease E activity
AB237_0639	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AB237_0641	COG0560	Phosphoserine phosphatase
AB237_0643	COG2249	NAD(P)H dehydrogenase (quinone) activity
AB237_0651	COG1113	amino acid transport
AB237_0652	COG2828	Protein conserved in bacteria
AB237_0653	COG0142	geranyltranstransferase activity
AB237_0654	COG2315	Protein conserved in bacteria
AB237_0657	COG1752	Esterase of the alpha-beta hydrolase superfamily
AB237_0661	COG2194	sulfuric ester hydrolase activity
AB237_0662	COG0745	RESPONSE REGULATOR receiver
AB237_0663	COG0642	Histidine kinase
AB237_0665	COG0004	ammonium transporteR
AB237_0666	COG0583	DNA-binding transcription factor activity
AB237_0670	COG0525	valine-tRNA ligase activity
AB237_0672	COG1028	Short-chain dehydrogenase reductase Sdr
AB237_0674	COG0393	Putative heavy-metal-binding
AB237_0675	COG0393	Putative heavy-metal-binding
AB237_0677	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AB237_0678	COG0671	phosphoesterase, PA-phosphatase related
AB237_0682	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AB237_0685	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AB237_0685	COG1648	precorrin-2 dehydrogenase activity
AB237_0686	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AB237_0687	COG1733	regulation of RNA biosynthetic process
AB237_0689	COG0531	amino acid
AB237_0692	COG0321	lipoyl(octanoyl) transferase activity
AB237_0693	COG2921	Belongs to the UPF0250 family
AB237_0700	COG2009	succinate dehydrogenase
AB237_0701	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AB237_0702	COG1053	succinate dehydrogenase
AB237_0703	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AB237_0706	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AB237_0710	COG2354	Protein conserved in bacteria
AB237_0711	COG2321	neutral zinc metallopeptidase
AB237_0715	COG2843	Capsule synthesis protein
AB237_0717	COG0589	response to stress
AB237_0721	COG0505	Belongs to the CarA family
AB237_0726	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AB237_0727	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AB237_0737	COG0477	Major facilitator Superfamily
AB237_0738	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AB237_0747	COG0584	glycerophosphoryl diester phosphodiesterase
AB237_0751	COG0741	lytic transglycosylase activity
AB237_0755	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AB237_0758	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AB237_0759	COG2826	transposase and inactivated derivatives, IS30 family
AB237_0765	COG0778	Nitroreductase
AB237_0768	COG1929	Belongs to the glycerate kinase type-1 family
AB237_0769	COG0243	molybdopterin cofactor binding
AB237_0770	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AB237_0772	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AB237_0775	COG1113	amino acid transport
AB237_0777	COG0019	diaminopimelate decarboxylase activity
AB237_0779	COG1280	lysine exporter protein (LysE YggA)
AB237_0780	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AB237_0786	COG0463	Glycosyl transferase, family 2
AB237_0789	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AB237_0795	COG4591	ABC-type transport system involved in lipoprotein release permease component
AB237_0796	COG1136	(ABC) transporter
AB237_0798	COG2826	transposase and inactivated derivatives, IS30 family
AB237_0799	COG0658	competence protein
AB237_0799	COG2333	competence protein COMEC
AB237_0800	COG0616	signal peptide processing
AB237_0800	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AB237_0801	COG0596	Alpha beta hydrolase
AB237_0802	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AB237_0804	COG0628	permease
AB237_0810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AB237_0814	COG0823	Involved in the tonB-independent uptake of proteins
AB237_0818	COG0824	Thioesterase
AB237_0819	COG1473	amidohydrolase
AB237_0823	COG0047	phosphoribosylformylglycinamidine synthase activity
AB237_0823	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AB237_0824	COG2814	Major facilitator Superfamily
AB237_0825	COG1024	Enoyl-CoA hydratase
AB237_0826	COG1051	belongs to the nudix hydrolase family
AB237_0826	COG1056	cytidyltransferase-related domain
AB237_0828	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AB237_0831	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AB237_0834	COG4625	pathogenesis
AB237_0835	COG0583	DNA-binding transcription factor activity
AB237_0836	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AB237_0837	COG4208	sulfate ABC transporter
AB237_0838	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AB237_0840	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AB237_0841	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AB237_0842	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AB237_0846	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AB237_0849	COG0681	Belongs to the peptidase S26 family
AB237_0851	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AB237_0852	COG1381	Involved in DNA repair and RecF pathway recombination
AB237_0853	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AB237_0855	COG4221	oxidoreductase activity
AB237_0864	COG0556	nucleotide-excision repair
AB237_0874	COG2070	2-Nitropropane dioxygenase
AB237_0879	COG1215	transferase activity, transferring glycosyl groups
AB237_0881	COG0415	Belongs to the DNA photolyase family
AB237_0883	COG1252	NADH dehydrogenase
AB237_0884	COG1686	Belongs to the peptidase S11 family
AB237_0887	COG1187	pseudouridine synthase activity
AB237_0891	COG0477	Major facilitator Superfamily
AB237_0892	COG0583	DNA-binding transcription factor activity
AB237_0895	COG0612	Peptidase, M16
AB237_0900	COG0352	thiamine-phosphate diphosphorylase activity
AB237_0907	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AB237_0910	COG1309	transcriptional regulator
AB237_0912	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AB237_0913	COG0076	glutamate decarboxylase activity
AB237_0915	COG1522	sequence-specific DNA binding
AB237_0916	COG3961	Belongs to the TPP enzyme family
AB237_0917	COG1113	amino acid transport
AB237_0918	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AB237_0919	COG0573	inorganic phosphate transmembrane transporter activity
AB237_0921	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AB237_0922	COG0616	signal peptide processing
AB237_0928	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AB237_0929	COG1686	Belongs to the peptidase S11 family
AB237_0932	COG2826	transposase and inactivated derivatives, IS30 family
AB237_0935	COG0583	DNA-binding transcription factor activity
AB237_0936	COG1067	ATP-dependent peptidase activity
AB237_0944	COG0776	regulation of translation
AB237_0947	COG3267	Type II secretory pathway component ExeA
AB237_0947	COG3409	Peptidoglycan-binding domain 1 protein
AB237_0951	COG0681	Belongs to the peptidase S26 family
AB237_0955	COG4373	Mu-like prophage FluMu protein gp28
AB237_0956	COG4383	Mu-like prophage protein gp29
AB237_0957	COG2369	cell adhesion
AB237_0959	COG4397	Mu-like prophage major head subunit gpT
AB237_0977	COG1966	Carbon starvation protein
AB237_0983	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AB237_0983	COG2508	Transcriptional regulator
AB237_0987	COG1113	amino acid transport
AB237_0988	COG0583	DNA-binding transcription factor activity
AB237_0989	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AB237_0990	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AB237_0992	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AB237_0993	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AB237_0993	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AB237_0999	COG2814	Major facilitator Superfamily
AB237_1000	COG4948	Mandelate Racemase Muconate Lactonizing
AB237_1002	COG1309	transcriptional regulator
AB237_1005	COG1741	Belongs to the pirin family
AB237_1010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AB237_1011	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AB237_1012	COG4605	iron ion homeostasis
AB237_1013	COG4604	ABC transporter, ATP-binding protein
AB237_1014	COG4607	ABC-type enterochelin transport system periplasmic component
AB237_1015	COG4774	siderophore transport
AB237_1017	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AB237_1018	COG1021	2,3-dihydroxybenzoate-AMP ligase
AB237_1019	COG3433	isochorismatase activity
AB237_1019	COG1535	isochorismatase
AB237_1021	COG1132	(ABC) transporter
AB237_1023	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AB237_1025	COG1169	isochorismate synthase
AB237_1028	COG3739	integral membrane protein
AB237_1036	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AB237_1042	COG0308	aminopeptidase N
AB237_1043	COG0512	Glutamine amidotransferase of anthranilate synthase
AB237_1078	COG2826	transposase and inactivated derivatives, IS30 family
AB237_1079	COG0739	heme binding
AB237_1084	COG0582	viral genome integration into host DNA
AB237_1086	COG3104	oligopeptide transport
AB237_1089	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AB237_1095	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AB237_1096	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AB237_1097	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AB237_1101	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AB237_1102	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AB237_1103	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AB237_1106	COG1960	acyl-CoA dehydrogenase activity
AB237_1107	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AB237_1108	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AB237_1110	COG2223	nitrite transmembrane transporter activity
AB237_1112	COG0024	Methionine aminopeptidase
AB237_1113	COG0052	Belongs to the universal ribosomal protein uS2 family
AB237_1116	COG2207	Transcriptional regulator
AB237_1121	COG2951	lytic endotransglycosylase activity
AB237_1122	COG0772	Belongs to the SEDS family
AB237_1125	COG0842	Transport permease protein
AB237_1126	COG1131	(ABC) transporter
AB237_1133	COG1538	Outer membrane efflux protein
AB237_1135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AB237_1138	COG4215	(ABC) transporter
AB237_1139	COG4160	amino acid transport
AB237_1140	COG4598	ABC transporter
AB237_1142	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AB237_1143	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AB237_1146	COG1720	tRNA m6t6A37 methyltransferase activity
AB237_1150	COG0745	RESPONSE REGULATOR receiver
AB237_1151	COG0642	Histidine kinase
AB237_1152	COG0494	nUDIX hydrolase
AB237_1154	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AB237_1155	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AB237_1156	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AB237_1157	COG1301	dicarboxylic acid transport
AB237_1158	COG1960	acyl-CoA dehydrogenase activity
AB237_1159	COG2819	hydrolase of the alpha beta superfamily
AB237_1161	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AB237_1163	COG2195	Cleaves the N-terminal amino acid of tripeptides
AB237_1164	COG1234	tRNA 3'-trailer cleavage
AB237_1170	COG2363	Small membrane protein
AB237_1172	COG0513	Belongs to the DEAD box helicase family
AB237_1174	COG0778	Nitroreductase
AB237_1180	COG1286	toxin biosynthetic process
AB237_1185	COG4783	chaperone-mediated protein folding
AB237_1186	COG1610	YqeY-like protein
AB237_1199	COG3316	Transposase and inactivated derivatives
AB237_1211	COG3173	Aminoglycoside phosphotransferase
AB237_1212	COG2433	Pfam Transposase IS66
AB237_1216	COG1301	dicarboxylic acid transport
AB237_1217	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AB237_1218	COG2011	ABC-type metal ion transport system permease component
AB237_1219	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AB237_1220	COG1464	Belongs to the NlpA lipoprotein family
AB237_1221	COG0151	Belongs to the GarS family
AB237_1222	COG0138	bifunctional purine biosynthesis protein purh
AB237_1227	COG2308	Evidence 4 Homologs of previously reported genes of
AB237_1228	COG1305	Transglutaminase-like
AB237_1230	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AB237_1231	COG0305	Participates in initiation and elongation during chromosome replication
AB237_1235	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AB237_1237	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AB237_1238	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AB237_1243	COG0726	polysaccharide deacetylase
AB237_1243	COG1649	PFAM Uncharacterised BCR, COG1649
AB237_1244	COG1215	transferase activity, transferring glycosyl groups
AB237_1245	COG3658	cytochrome
AB237_1247	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB237_1250	COG0583	DNA-binding transcription factor activity
AB237_1254	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB237_1255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AB237_1258	COG1960	acyl-CoA dehydrogenase activity
AB237_1259	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AB237_1260	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AB237_1265	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AB237_1266	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AB237_1268	COG2205	protein histidine kinase activity
AB237_1269	COG0745	RESPONSE REGULATOR receiver
AB237_1270	COG0174	glutamine synthetase
AB237_1274	COG0729	surface antigen
AB237_1277	COG2826	transposase and inactivated derivatives, IS30 family
AB237_1279	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AB237_1280	COG2814	Major facilitator Superfamily
AB237_1283	COG0583	DNA-binding transcription factor activity
AB237_1285	COG1187	pseudouridine synthase activity
AB237_1289	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AB237_1291	COG1923	regulation of RNA biosynthetic process
AB237_1292	COG0697	spore germination
AB237_1294	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AB237_1297	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AB237_1297	COG0519	Catalyzes the synthesis of GMP from XMP
AB237_1298	COG4302	ethanolamine ammonia-lyase activity
AB237_1299	COG4303	Ethanolamine ammonia lyase large subunit
AB237_1300	COG0531	amino acid
AB237_1303	COG1454	alcohol dehydrogenase
AB237_1304	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AB237_1306	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AB237_1309	COG0308	aminopeptidase N
AB237_1311	COG4221	oxidoreductase activity
AB237_1313	COG1605	Chorismate mutase
AB237_1316	COG1309	transcriptional regulator
AB237_1318	COG0668	transmembrane transport
AB237_1325	COG4773	Receptor
AB237_1328	COG0488	(ABC) transporter
AB237_1329	COG0589	response to stress
AB237_1331	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AB237_1333	COG3135	benzoate transporter
AB237_1334	COG1522	sequence-specific DNA binding
AB237_1337	COG0583	DNA-binding transcription factor activity
AB237_1338	COG0183	Belongs to the thiolase family
AB237_1344	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AB237_1346	COG0824	Thioesterase
AB237_1347	COG1454	alcohol dehydrogenase
AB237_1349	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AB237_1353	COG0069	glutamate synthase activity
AB237_1355	COG2826	transposase and inactivated derivatives, IS30 family
AB237_1357	COG2826	transposase and inactivated derivatives, IS30 family
AB237_1415	COG0739	heme binding
AB237_1415	COG0741	lytic transglycosylase activity
AB237_1415	COG1196	nuclear chromosome segregation
AB237_1428	COG2814	Major facilitator Superfamily
AB237_1431	COG0511	ligase activity, forming carbon-carbon bonds
AB237_1434	COG1116	anion transmembrane transporter activity
AB237_1434	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AB237_1435	COG0745	RESPONSE REGULATOR receiver
AB237_1436	COG2146	nitrite reductase [NAD(P)H] activity
AB237_1436	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AB237_1437	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AB237_1438	COG0243	molybdopterin cofactor binding
AB237_1439	COG0243	molybdopterin cofactor binding
AB237_1440	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AB237_1442	COG0315	cyclic pyranopterin monophosphate synthase activity
AB237_1442	COG0521	Mo-molybdopterin cofactor biosynthetic process
AB237_1443	COG0303	'Molybdopterin
AB237_1445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AB237_1446	COG0697	spore germination
AB237_1449	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AB237_1450	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AB237_1463	COG2204	response regulator
AB237_1464	COG3852	Histidine kinase
AB237_1468	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AB237_1469	COG0575	Belongs to the CDS family
AB237_1475	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AB237_1477	COG2137	regulation of response to DNA damage stimulus
AB237_1479	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AB237_1480	COG1011	Hydrolase
AB237_1483	COG1522	sequence-specific DNA binding
AB237_1485	COG1113	amino acid transport
AB237_1488	COG0659	secondary active sulfate transmembrane transporter activity
AB237_1489	COG2135	peptidase activity
AB237_1492	COG5001	Diguanylate cyclase
AB237_1492	COG3300	MHYT domain
AB237_1494	COG2826	transposase and inactivated derivatives, IS30 family
AB237_1497	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AB237_1497	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AB237_1497	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AB237_1498	COG1105	Belongs to the carbohydrate kinase PfkB family
AB237_1499	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AB237_1499	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB237_1504	COG0024	Methionine aminopeptidase
AB237_1505	COG0583	DNA-binding transcription factor activity
AB237_1507	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AB237_1508	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AB237_1509	COG0516	GMP reductase activity
AB237_1509	COG0517	IMP dehydrogenase activity
AB237_1513	COG0552	protein localization to endoplasmic reticulum
AB237_1515	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AB237_1518	COG1294	oxidase, subunit
AB237_1521	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AB237_1522	COG4774	siderophore transport
AB237_1525	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AB237_1526	COG0569	domain protein
AB237_1527	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AB237_1532	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AB237_1533	COG0542	response to heat
AB237_1535	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AB237_1541	COG0446	pyridine nucleotide-disulphide oxidoreductase
AB237_1541	COG1902	pentaerythritol trinitrate reductase activity
AB237_1543	COG2826	transposase and inactivated derivatives, IS30 family
AB237_1551	COG2323	membrane
AB237_1552	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AB237_1554	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AB237_1555	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AB237_1556	COG0183	Belongs to the thiolase family
AB237_1557	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AB237_1558	COG0596	Alpha beta hydrolase
AB237_1559	COG2271	Major facilitator Superfamily
AB237_1560	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AB237_1561	COG3485	protocatechuate 3,4-dioxygenase
AB237_1562	COG3485	protocatechuate 3,4-dioxygenase
AB237_1563	COG0710	3-dehydroquinate dehydratase activity
AB237_1564	COG3420	alginic acid biosynthetic process
AB237_1565	COG3659	wide pore channel activity
AB237_1566	COG4993	Dehydrogenase
AB237_1570	COG1414	Transcriptional regulator
AB237_1571	COG0583	DNA-binding transcription factor activity
AB237_1572	COG1960	acyl-CoA dehydrogenase activity
AB237_1577	COG2814	Major facilitator Superfamily
AB237_1579	COG0154	amidase activity
AB237_1583	COG4638	Rieske (2fe-2S)
AB237_1585	COG1028	Short-chain dehydrogenase reductase Sdr
AB237_1587	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AB237_1589	COG3733	amine oxidase
AB237_1591	COG1012	belongs to the aldehyde dehydrogenase family
AB237_1593	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AB237_1594	COG0183	Belongs to the thiolase family
AB237_1595	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AB237_1596	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AB237_1598	COG4829	muconolactone delta-isomerase
AB237_1599	COG4948	Mandelate Racemase Muconate Lactonizing
AB237_1600	COG0583	DNA-binding transcription factor activity
AB237_1602	COG2186	Transcriptional regulator
AB237_1606	COG1012	belongs to the aldehyde dehydrogenase family
AB237_1608	COG1960	acyl-CoA dehydrogenase activity
AB237_1609	COG1028	Short-chain dehydrogenase reductase Sdr
AB237_1610	COG3829	transcription factor binding
AB237_1614	COG1012	belongs to the aldehyde dehydrogenase family
AB237_1617	COG0753	catalase activity
AB237_1621	COG1846	Transcriptional regulator
AB237_1622	COG1902	pentaerythritol trinitrate reductase activity
AB237_1622	COG0446	pyridine nucleotide-disulphide oxidoreductase
AB237_1623	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AB237_1629	COG1309	transcriptional regulator
AB237_1631	COG1335	isochorismatase
AB237_1632	COG0583	DNA-binding transcription factor activity
AB237_1634	COG0475	glutathione-regulated potassium exporter activity
AB237_1634	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AB237_1636	COG1473	amidohydrolase
AB237_1638	COG2831	hemolysin activation secretion protein
AB237_1639	COG3210	domain, Protein
AB237_1647	COG0583	DNA-binding transcription factor activity
AB237_1652	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AB237_1653	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AB237_1655	COG2826	transposase and inactivated derivatives, IS30 family
AB237_1659	COG1012	belongs to the aldehyde dehydrogenase family
AB237_1660	COG0129	dihydroxy-acid dehydratase activity
AB237_1662	COG0583	DNA-binding transcription factor activity
AB237_1663	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AB237_1665	COG2084	Dehydrogenase
AB237_1666	COG2207	Transcriptional regulator
AB237_1668	COG1064	alcohol dehydrogenase
AB237_1674	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AB237_1688	COG2826	transposase and inactivated derivatives, IS30 family
AB237_1695	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AB237_1702	COG2826	transposase and inactivated derivatives, IS30 family
AB237_1705	COG1028	Short-chain dehydrogenase reductase Sdr
AB237_1708	COG2207	Transcriptional regulator
AB237_1710	COG2205	protein histidine kinase activity
AB237_1711	COG0745	RESPONSE REGULATOR receiver
AB237_1712	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AB237_1713	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AB237_1714	COG1538	Outer membrane efflux protein
AB237_1716	COG2072	flavoprotein involved in K transport
AB237_1718	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AB237_1721	COG3539	Fimbrial protein
AB237_1727	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AB237_1729	COG0753	catalase activity
AB237_1732	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AB237_1743	COG1535	isochorismatase
AB237_1743	COG3433	isochorismatase activity
AB237_1744	COG1028	Short-chain dehydrogenase reductase Sdr
AB237_1745	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AB237_1746	COG4149	molybdate abc transporter
AB237_1747	COG0725	ABC transporter, periplasmic molybdate-binding protein
AB237_1749	COG4638	Rieske (2fe-2S)
AB237_1750	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AB237_1751	COG0543	2 iron, 2 sulfur cluster binding
AB237_1751	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AB237_1754	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AB237_1756	COG1028	Short-chain dehydrogenase reductase Sdr
AB237_1757	COG0412	Dienelactone hydrolase
AB237_1759	COG2207	Transcriptional regulator
AB237_1762	COG1028	Short-chain dehydrogenase reductase Sdr
AB237_1763	COG2610	gluconate transmembrane transporter activity
AB237_1765	COG0583	DNA-binding transcription factor activity
AB237_1767	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AB237_1768	COG2031	fatty acid transporter
AB237_1769	COG0183	Belongs to the thiolase family
AB237_1770	COG0583	DNA-binding transcription factor activity
AB237_1771	COG0583	DNA-binding transcription factor activity
AB237_1772	COG1027	Aspartate ammonia-lyase
AB237_1775	COG4774	siderophore transport
AB237_1776	COG0477	Major facilitator Superfamily
AB237_1779	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB237_1780	COG4521	taurine ABC transporter
AB237_1785	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AB237_1786	COG1733	regulation of RNA biosynthetic process
AB237_1787	COG3708	Transcriptional regulator
AB237_1787	COG2207	Transcriptional regulator
AB237_1790	COG0730	response to heat
AB237_1792	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AB237_1792	COG3453	Protein conserved in bacteria
AB237_1794	COG3781	membrane
AB237_1795	COG1063	alcohol dehydrogenase
AB237_1797	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AB237_1798	COG0508	dehydrogenase complex catalyzes the overall conversion of
AB237_1799	COG0022	dehydrogenase e1 component
AB237_1800	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AB237_1803	COG3706	GGDEF domain
AB237_1806	COG0133	tryptophan synthase activity
AB237_1808	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AB237_1812	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AB237_1816	COG2226	methyltransferase
AB237_1825	COG0842	Transport permease protein
AB237_1826	COG1131	(ABC) transporter
AB237_1829	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AB237_1830	COG4773	Receptor
AB237_1832	COG0730	response to heat
AB237_1833	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AB237_1837	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AB237_1840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AB237_1846	COG4264	IucA IucC family
AB237_1847	COG4264	IucA IucC family
AB237_1851	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AB237_1854	COG1960	acyl-CoA dehydrogenase activity
AB237_1855	COG1960	acyl-CoA dehydrogenase activity
AB237_1856	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AB237_1857	COG2207	Transcriptional regulator
AB237_1858	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AB237_1863	COG0822	iron-sulfur transferase activity
AB237_1864	COG0316	Belongs to the HesB IscA family
AB237_1870	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AB237_1874	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AB237_1875	COG0702	epimerase
AB237_1882	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AB237_1884	COG0339	signal peptide processing
AB237_1892	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AB237_1898	COG0739	heme binding
AB237_1898	COG1196	nuclear chromosome segregation
AB237_1898	COG0741	lytic transglycosylase activity
AB237_1907	COG4695	Portal protein
AB237_1918	COG0305	Participates in initiation and elongation during chromosome replication
AB237_1925	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AB237_1935	COG0590	tRNA wobble adenosine to inosine editing
AB237_1941	COG2165	general secretion pathway protein
AB237_1944	COG0084	hydrolase, TatD family'
AB237_1948	COG1663	tetraacyldisaccharide 4'-kinase activity
AB237_1949	COG1132	(ABC) transporter
AB237_1951	COG0811	peptide transport
AB237_1952	COG1475	DNA binding
AB237_1953	COG1192	Involved in chromosome partitioning
AB237_1955	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AB237_1958	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AB237_1959	COG0191	fructose-bisphosphate aldolase activity
AB237_1961	COG0424	maF-like protein
AB237_1962	COG2850	peptidyl-arginine hydroxylation
AB237_1964	COG0640	Transcriptional regulator
AB237_1966	COG3619	membrane
AB237_1967	COG3122	Protein conserved in bacteria
AB237_1968	COG1132	(ABC) transporter
AB237_1972	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AB237_1973	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AB237_1975	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AB237_1975	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AB237_1975	COG0506	proline dehydrogenase activity
AB237_1976	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AB237_1978	COG3698	Phosphodiester glycosidase
AB237_1980	COG2353	YceI-like domain
AB237_1982	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AB237_1990	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AB237_1990	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AB237_1994	COG3539	Fimbrial protein
AB237_1995	COG3121	Chaperone
AB237_1999	COG0697	spore germination
AB237_2001	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AB237_2003	COG0583	DNA-binding transcription factor activity
AB237_2005	COG2826	transposase and inactivated derivatives, IS30 family
AB237_2009	COG1309	transcriptional regulator
AB237_2012	COG1522	sequence-specific DNA binding
AB237_2014	COG1126	abc transporter atp-binding protein
AB237_2015	COG0765	amino acid transport
AB237_2016	COG0765	amino acid transport
AB237_2023	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AB237_2024	COG2011	ABC-type metal ion transport system permease component
AB237_2025	COG0012	GTP binding
AB237_2030	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AB237_2036	COG0386	Belongs to the glutathione peroxidase family
AB237_2038	COG0436	Aminotransferase
AB237_2046	COG3634	alkyl hydroperoxide reductase activity
AB237_2048	COG0583	DNA-binding transcription factor activity
AB237_2049	COG0798	PFAM Bile acid sodium symporter
AB237_2050	COG0640	Transcriptional regulator
AB237_2052	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AB237_2054	COG0583	DNA-binding transcription factor activity
AB237_2056	COG1953	Uracil, thiamine, allantoin
AB237_2058	COG2175	clavaminate synthase activity
AB237_2059	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB237_2060	COG4521	taurine ABC transporter
AB237_2063	COG0477	Major facilitator Superfamily
AB237_2069	COG1271	oxidase subunit
AB237_2070	COG1294	oxidase, subunit
AB237_2071	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AB237_2075	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AB237_2078	COG3052	prosthetic group binding
AB237_2079	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AB237_2081	COG2814	Major facilitator Superfamily
AB237_2085	COG1346	cytolysis
AB237_2087	COG0583	DNA-binding transcription factor activity
AB237_2088	COG0625	glutathione transferase activity
AB237_2089	COG0625	glutathione transferase activity
AB237_2090	COG0583	DNA-binding transcription factor activity
AB237_2093	COG1045	serine acetyltransferase
AB237_2094	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AB237_2095	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AB237_2096	COG1280	lysine exporter protein (LysE YggA)
AB237_2098	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AB237_2099	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AB237_2100	COG1126	abc transporter atp-binding protein
AB237_2101	COG0765	amino acid transport
AB237_2102	COG0765	amino acid transport
AB237_2105	COG0784	Response regulator, receiver
AB237_2105	COG2205	protein histidine kinase activity
AB237_2109	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AB237_2112	COG1028	Short-chain dehydrogenase reductase Sdr
AB237_2118	COG2826	transposase and inactivated derivatives, IS30 family
AB237_2121	COG0583	DNA-binding transcription factor activity
AB237_2125	COG0318	PFAM AMP-dependent synthetase and ligase
AB237_2126	COG1309	transcriptional regulator
AB237_2127	COG1960	acyl-CoA dehydrogenase activity
AB237_2128	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AB237_2129	COG1024	Enoyl-CoA hydratase
AB237_2132	COG0583	DNA-binding transcription factor activity
AB237_2135	COG1960	acyl-CoA dehydrogenase activity
AB237_2137	COG2814	Major facilitator Superfamily
AB237_2139	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AB237_2140	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AB237_2141	COG2814	Major facilitator Superfamily
AB237_2142	COG1960	acyl-CoA dehydrogenase activity
AB237_2143	COG1024	Enoyl-CoA hydratase
AB237_2144	COG1028	Short-chain dehydrogenase reductase Sdr
AB237_2145	COG1250	3-hydroxyacyl-CoA dehydrogenase
AB237_2147	COG2814	Major facilitator Superfamily
AB237_2149	COG1024	Enoyl-CoA hydratase
AB237_2152	COG1960	acyl-CoA dehydrogenase activity
AB237_2153	COG2814	Major facilitator Superfamily
AB237_2154	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AB237_2155	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AB237_2159	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB237_2160	COG1414	Transcriptional regulator
AB237_2162	COG0583	DNA-binding transcription factor activity
AB237_2163	COG1012	belongs to the aldehyde dehydrogenase family
AB237_2165	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AB237_2166	COG1012	belongs to the aldehyde dehydrogenase family
AB237_2167	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB237_2168	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AB237_2169	COG2267	carboxylic ester hydrolase activity
AB237_2172	COG3038	cytochrome b561
AB237_2173	COG0753	catalase activity
AB237_2179	COG2050	protein possibly involved in aromatic compounds catabolism
AB237_2181	COG3327	negative regulation of DNA-templated transcription, initiation
AB237_2182	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AB237_2183	COG0183	Belongs to the thiolase family
AB237_2184	COG1250	3-hydroxyacyl-CoA dehydrogenase
AB237_2185	COG1024	Enoyl-CoA hydratase
AB237_2186	COG1024	Enoyl-CoA hydratase
AB237_2187	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AB237_2188	COG2151	metal-sulfur cluster biosynthetic enzyme
AB237_2189	COG3396	Phenylacetate-CoA oxygenase
AB237_2190	COG3460	Phenylacetate-CoA oxygenase
AB237_2191	COG3396	Phenylacetate-CoA oxygenase
AB237_2192	COG1012	belongs to the aldehyde dehydrogenase family
AB237_2192	COG2030	dehydratase
AB237_2193	COG1760	l-serine dehydratase
AB237_2194	COG0531	amino acid
AB237_2195	COG1012	belongs to the aldehyde dehydrogenase family
AB237_2198	COG0446	pyridine nucleotide-disulphide oxidoreductase
AB237_2200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AB237_2203	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AB237_2205	COG0789	Transcriptional regulator
AB237_2208	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AB237_2209	COG2826	transposase and inactivated derivatives, IS30 family
AB237_2212	COG2807	transmembrane transport
AB237_2213	COG0590	tRNA wobble adenosine to inosine editing
AB237_2215	COG0583	DNA-binding transcription factor activity
AB237_2222	COG2885	chlorophyll binding
AB237_2222	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AB237_2233	COG1116	anion transmembrane transporter activity
AB237_2234	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AB237_2236	COG0864	Transcriptional regulator
AB237_2238	COG2249	NAD(P)H dehydrogenase (quinone) activity
AB237_2239	COG0439	Biotin carboxylase
AB237_2242	COG1063	alcohol dehydrogenase
AB237_2244	COG1309	transcriptional regulator
AB237_2249	COG0038	chloride channel
AB237_2250	COG4770	biotin carboxylase activity
AB237_2254	COG1914	H( )-stimulated, divalent metal cation uptake system
AB237_2255	COG0583	DNA-binding transcription factor activity
AB237_2258	COG3209	COG3209 Rhs family protein
AB237_2259	COG3501	Rhs element vgr protein
AB237_2264	COG1250	3-hydroxyacyl-CoA dehydrogenase
AB237_2268	COG2814	Major facilitator Superfamily
AB237_2270	COG1560	Kdo2-lipid A biosynthetic process
AB237_2272	COG5006	permease, DMT superfamily
AB237_2273	COG1522	sequence-specific DNA binding
AB237_2276	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AB237_2284	COG1538	Outer membrane efflux protein
AB237_2285	COG1137	ATPase activity
AB237_2286	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AB237_2288	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AB237_2289	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AB237_2289	COG0517	IMP dehydrogenase activity
AB237_2295	COG1733	regulation of RNA biosynthetic process
AB237_2296	COG2814	Major facilitator Superfamily
AB237_2301	COG1280	lysine exporter protein (LysE YggA)
AB237_2306	COG1570	exodeoxyribonuclease VII activity
AB237_2314	COG0583	DNA-binding transcription factor activity
AB237_2315	COG4638	Rieske (2fe-2S)
AB237_2316	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AB237_2317	COG0543	2 iron, 2 sulfur cluster binding
AB237_2317	COG0633	Ferredoxin
AB237_2318	COG1028	Short-chain dehydrogenase reductase Sdr
AB237_2319	COG2826	transposase and inactivated derivatives, IS30 family
AB237_2320	COG3135	benzoate transporter
AB237_2321	COG2814	Major facilitator Superfamily
AB237_2324	COG1643	Atp-dependent helicase
AB237_2325	COG0450	alkyl hydroperoxide reductase
AB237_2326	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AB237_2327	COG3634	alkyl hydroperoxide reductase activity
AB237_2331	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AB237_2332	COG0625	glutathione transferase activity
AB237_2334	COG2885	chlorophyll binding
AB237_2344	COG1765	OsmC-like protein
AB237_2348	COG0667	Aldo Keto reductase
AB237_2351	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AB237_2353	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AB237_2356	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AB237_2358	COG3038	cytochrome b561
AB237_2359	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AB237_2360	COG3316	Transposase and inactivated derivatives
AB237_2364	COG1012	belongs to the aldehyde dehydrogenase family
AB237_2368	COG0531	amino acid
AB237_2370	COG1113	amino acid transport
AB237_2376	COG3209	COG3209 Rhs family protein
AB237_2377	COG3501	Rhs element vgr protein
AB237_2380	COG4269	membrane
AB237_2383	COG1902	pentaerythritol trinitrate reductase activity
AB237_2383	COG0446	pyridine nucleotide-disulphide oxidoreductase
AB237_2385	COG3706	GGDEF domain
AB237_2385	COG2203	Gaf domain
AB237_2385	COG4251	negative regulation of phosphorylation
AB237_2385	COG5001	Diguanylate cyclase
AB237_2387	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AB237_2391	COG4172	Belongs to the ABC transporter superfamily
AB237_2392	COG4174	ABC transporter (Permease)
AB237_2394	COG0741	lytic transglycosylase activity
AB237_2394	COG1388	LysM domain
AB237_2394	COG0741	lytic transglycosylase activity
AB237_2394	COG1388	LysM domain
AB237_2395	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AB237_2403	COG0583	DNA-binding transcription factor activity
AB237_2404	COG1279	arginine transmembrane transporter activity
AB237_2408	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB237_2409	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB237_2410	COG0006	proline dipeptidase activity
AB237_2415	COG2194	sulfuric ester hydrolase activity
AB237_2420	COG0741	lytic transglycosylase activity
AB237_2420	COG1196	nuclear chromosome segregation
AB237_2420	COG0739	heme binding
AB237_2443	COG2826	transposase and inactivated derivatives, IS30 family
AB237_2461	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AB237_2466	COG3384	dioxygenase
AB237_2468	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AB237_2469	COG2878	Part of a membrane complex involved in electron transport
AB237_2470	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AB237_2474	COG0768	penicillin binding
AB237_2475	COG0742	ribosomal rna small subunit methyltransferase
AB237_2478	COG0830	nickel cation binding
AB237_2480	COG0804	urea catabolic process
AB237_2488	COG1253	flavin adenine dinucleotide binding
AB237_2489	COG2851	Citrate transporter
AB237_2498	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AB237_2500	COG0583	DNA-binding transcription factor activity
AB237_2505	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AB237_2506	COG4181	ATPase activity
AB237_2516	COG0306	phosphate transporter
AB237_2518	COG3958	Transketolase
AB237_2519	COG3959	Transketolase, thiamine diphosphate binding domain
AB237_2520	COG2271	Major facilitator Superfamily
AB237_2521	COG1028	Short-chain dehydrogenase reductase Sdr
AB237_2522	COG0583	DNA-binding transcription factor activity
AB237_2525	COG2223	nitrite transmembrane transporter activity
AB237_2526	COG2207	Transcriptional regulator
AB237_2527	COG2066	Belongs to the glutaminase family
AB237_2528	COG0242	peptide deformylase activity
AB237_2529	COG0477	Major facilitator Superfamily
AB237_2531	COG0028	Belongs to the TPP enzyme family
AB237_2534	COG1028	Short-chain dehydrogenase reductase Sdr
AB237_2535	COG2267	carboxylic ester hydrolase activity
AB237_2537	COG2271	Major facilitator Superfamily
AB237_2538	COG0446	pyridine nucleotide-disulphide oxidoreductase
AB237_2540	COG1028	Short-chain dehydrogenase reductase Sdr
AB237_2544	COG1414	Transcriptional regulator
AB237_2547	COG1024	Enoyl-CoA hydratase
AB237_2549	COG1215	transferase activity, transferring glycosyl groups
AB237_2550	COG1649	PFAM Uncharacterised BCR, COG1649
AB237_2550	COG0726	polysaccharide deacetylase
AB237_2552	COG4681	YaeQ
AB237_2554	COG0523	cobalamin synthesis protein
AB237_2555	COG1607	acyl-coa hydrolase
AB237_2557	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AB237_2558	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AB237_2559	COG1309	transcriptional regulator
AB237_2564	COG2040	homocysteine
AB237_2565	COG0531	amino acid
AB237_2576	COG1595	DNA-templated transcription, initiation
AB237_2578	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AB237_2579	COG0477	Major facilitator Superfamily
AB237_2583	COG0084	hydrolase, TatD family'
AB237_2587	COG2826	transposase and inactivated derivatives, IS30 family
AB237_2596	COG0582	viral genome integration into host DNA
AB237_2598	COG0405	Gamma-glutamyltransferase
AB237_2599	COG2814	Major facilitator Superfamily
AB237_2606	COG0420	3'-5' exonuclease activity
AB237_2611	COG0735	belongs to the Fur family
AB237_2612	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AB237_2615	COG0121	glutamine amidotransferase
AB237_2618	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AB237_2620	COG0210	DNA helicase
AB237_2621	COG2885	chlorophyll binding
AB237_2622	COG0204	Acyl-transferase
AB237_2625	COG2894	cell division
AB237_2629	COG1280	lysine exporter protein (LysE YggA)
AB237_2630	COG1674	ftsk spoiiie
AB237_2630	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AB237_2631	COG0492	ferredoxin-NADP+ reductase activity
AB237_2632	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AB237_2634	COG0456	acetyltransferase
AB237_2646	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AB237_2646	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AB237_2650	COG1012	belongs to the aldehyde dehydrogenase family
AB237_2654	COG0473	3-isopropylmalate dehydrogenase activity
AB237_2655	COG0583	DNA-binding transcription factor activity
AB237_2661	COG0564	pseudouridine synthase activity
AB237_2663	COG0358	DNA primase activity
AB237_2666	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AB237_2671	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AB237_2677	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AB237_2679	COG0351	phosphomethylpyrimidine kinase
AB237_2679	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AB237_2679	COG0352	thiamine-phosphate diphosphorylase activity
AB237_2680	COG1652	LysM domain
AB237_2684	COG1399	metal-binding, possibly nucleic acid-binding protein
AB237_2685	COG3101	peptidyl-lysine hydroxylation
AB237_2686	COG0009	L-threonylcarbamoyladenylate synthase
AB237_2687	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AB237_2690	COG4106	trans-aconitate 2-methyltransferase activity
AB237_2693	COG0596	Alpha beta hydrolase
AB237_2693	COG2226	methyltransferase
AB237_2693	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AB237_2694	COG1877	trehalose-phosphatase activity
AB237_2695	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AB237_2696	COG2223	nitrite transmembrane transporter activity
AB237_2702	COG1002	Type II restriction enzyme, methylase subunits
AB237_2707	COG1196	nuclear chromosome segregation
AB237_2709	COG0730	response to heat
AB237_2712	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AB237_2714	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AB237_2723	COG0489	protein tyrosine kinase activity
AB237_2725	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AB237_2725	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AB237_2731	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AB237_2732	COG2081	HI0933 family
AB237_2733	COG0668	transmembrane transport
AB237_2736	COG0583	DNA-binding transcription factor activity
AB237_2739	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AB237_2740	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AB237_2746	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AB237_2753	COG2205	protein histidine kinase activity
AB237_2754	COG0745	RESPONSE REGULATOR receiver
AB237_2756	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AB237_2758	COG2826	transposase and inactivated derivatives, IS30 family
AB237_2761	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AB237_2762	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AB237_2764	COG0583	DNA-binding transcription factor activity
AB237_2768	COG1473	amidohydrolase
AB237_2770	COG0583	DNA-binding transcription factor activity
AB237_2773	COG0583	DNA-binding transcription factor activity
AB237_2774	COG1053	succinate dehydrogenase
AB237_2776	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB237_2777	COG2814	Major facilitator Superfamily
AB237_2778	COG1960	acyl-CoA dehydrogenase activity
AB237_2779	COG0583	DNA-binding transcription factor activity
AB237_2780	COG1063	alcohol dehydrogenase
AB237_2783	COG0582	viral genome integration into host DNA
AB237_2784	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AB237_2787	COG1122	ATPase activity
AB237_2790	COG3646	Phage regulatory protein
AB237_2803	COG0860	N-Acetylmuramoyl-L-alanine amidase
AB237_2803	COG3409	Peptidoglycan-binding domain 1 protein
AB237_2810	COG4695	Portal protein
AB237_2816	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AB237_2817	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AB237_2818	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AB237_2821	COG3667	copper resistance
AB237_2822	COG2132	Multicopper oxidase
AB237_2824	COG0561	phosphatase activity
AB237_2825	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AB237_2839	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AB237_2841	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AB237_2842	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AB237_2843	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AB237_2860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AB237_2862	COG1846	Transcriptional regulator
AB237_2863	COG1764	response to oxidative stress
AB237_2871	COG0037	tRNA processing
AB237_2873	COG0248	Ppx GppA phosphatase
AB237_2877	COG0072	phenylalanine-tRNA ligase activity
AB237_2882	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AB237_2884	COG1238	metal cluster binding
AB237_2885	COG0625	glutathione transferase activity
AB237_2888	COG0318	PFAM AMP-dependent synthetase and ligase
AB237_2889	COG3028	Belongs to the UPF0307 family
AB237_2890	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB237_2894	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AB237_2895	COG0617	tRNA 3'-terminal CCA addition
AB237_2896	COG3956	TIGRFAM MazG family protein
AB237_2898	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AB237_2902	COG5002	protein histidine kinase activity
AB237_2902	COG2205	protein histidine kinase activity
AB237_2902	COG0784	Response regulator, receiver
AB237_2903	COG1024	Enoyl-CoA hydratase
AB237_2904	COG2084	Dehydrogenase
AB237_2905	COG3622	Belongs to the hyi family
AB237_2908	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AB237_2909	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AB237_2910	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AB237_2911	COG0697	spore germination
AB237_2913	COG2814	Major facilitator Superfamily
AB237_2914	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AB237_2916	COG0583	DNA-binding transcription factor activity
AB237_2917	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AB237_2920	COG0084	hydrolase, TatD family'
AB237_2923	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AB237_2932	COG0440	acetolactate synthase activity
AB237_2933	COG0028	Belongs to the TPP enzyme family
AB237_2938	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AB237_2939	COG0577	efflux transmembrane transporter activity
AB237_2939	COG1136	(ABC) transporter
AB237_2942	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AB237_2943	COG1162	GTPase activity
AB237_2948	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AB237_2949	COG1028	Short-chain dehydrogenase reductase Sdr
AB237_2956	COG2986	histidine ammonia-lyase
AB237_2958	COG0318	PFAM AMP-dependent synthetase and ligase
AB237_2960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AB237_2967	COG1426	Protein conserved in bacteria
AB237_2973	COG0793	Belongs to the peptidase S41A family
AB237_2976	COG2267	carboxylic ester hydrolase activity
AB237_2978	COG1012	belongs to the aldehyde dehydrogenase family
AB237_2979	COG3265	gluconokinase activity
AB237_2981	COG0800	Aldolase
AB237_2983	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AB237_2984	COG0280	phosphate acetyltransferase
AB237_2984	COG0857	belongs to the CobB CobQ family
AB237_2985	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AB237_2985	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AB237_2989	COG0740	serine-type endopeptidase activity
AB237_2991	COG4774	siderophore transport
AB237_2993	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AB237_2995	COG2813	Specifically methylates the guanine in position
AB237_2995	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AB237_3012	COG0788	formyltetrahydrofolate deformylase activity
AB237_3015	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AB237_3015	COG4651	solute:proton antiporter activity
AB237_3018	COG0210	DNA helicase
AB237_3023	COG1733	regulation of RNA biosynthetic process
AB237_3026	COG1280	lysine exporter protein (LysE YggA)
AB237_3027	COG1560	Kdo2-lipid A biosynthetic process
AB237_3029	COG1301	dicarboxylic acid transport
AB237_3039	COG0473	3-isopropylmalate dehydrogenase activity
AB237_3050	COG0583	DNA-binding transcription factor activity
AB237_3052	COG0625	glutathione transferase activity
AB237_3053	COG2378	regulation of single-species biofilm formation
AB237_3054	COG0546	phosphoglycolate phosphatase activity
AB237_3056	COG1530	ribonuclease E activity
AB237_3060	COG0583	DNA-binding transcription factor activity
AB237_3061	COG4221	oxidoreductase activity
AB237_3062	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AB237_3064	COG0534	Mate efflux family protein
AB237_3067	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AB237_3074	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AB237_3075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AB237_3078	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AB237_3080	COG0644	oxidoreductase
AB237_3080	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AB237_3081	COG4535	Mg2 and Co2 transporter CorC
AB237_3083	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AB237_3087	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AB237_3088	COG0475	glutathione-regulated potassium exporter activity
AB237_3088	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AB237_3089	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AB237_3091	COG0484	heat shock protein binding
AB237_3092	COG0789	Transcriptional regulator
AB237_3093	COG0598	Magnesium transport protein CorA
AB237_3097	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AB237_3098	COG1074	ATP-dependent DNA helicase activity
AB237_3099	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AB237_3103	COG2226	methyltransferase
AB237_3106	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AB237_3107	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AB237_3110	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AB237_3110	COG2111	Na H antiporter
AB237_3111	COG0651	ATP synthesis coupled electron transport
AB237_3116	COG0195	Participates in both transcription termination and antitermination
AB237_3126	COG0237	dephospho-CoA kinase activity
AB237_3128	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AB237_3131	COG0497	DNA recombination
AB237_3133	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AB237_3138	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AB237_3138	COG2169	Transcriptional regulator
AB237_3139	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AB237_3152	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AB237_3155	COG0326	Molecular chaperone. Has ATPase activity
AB237_3158	COG2056	Na+-H+ antiporter family
AB237_3159	COG0596	Alpha beta hydrolase
AB237_3179	COG0546	phosphoglycolate phosphatase activity
AB237_3180	COG1716	ATPase activity
AB237_3185	COG2826	transposase and inactivated derivatives, IS30 family
AB237_3189	COG0181	hydroxymethylbilane synthase activity
AB237_3191	COG3275	phosphorelay sensor kinase activity
AB237_3194	COG1538	Outer membrane efflux protein
AB237_3195	COG0697	spore germination
AB237_3200	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AB237_3201	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AB237_3202	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AB237_3203	COG0772	Belongs to the SEDS family
AB237_3207	COG4974	Belongs to the 'phage' integrase family
AB237_3208	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AB237_3210	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AB237_3212	COG2197	response regulator
AB237_3215	COG0793	Belongs to the peptidase S41A family
AB237_3216	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AB237_3217	COG0795	lipopolysaccharide-transporting ATPase activity
AB237_3224	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AB237_3224	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AB237_3226	COG0004	ammonium transporteR
AB237_3227	COG0347	Belongs to the P(II) protein family
AB237_3228	COG0606	chelatase, subunit chli
AB237_3236	COG0659	secondary active sulfate transmembrane transporter activity
AB237_3237	COG0589	response to stress
AB237_3243	COG0606	chelatase, subunit chli
AB237_3244	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AB237_3246	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AB237_3249	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AB237_3252	COG0318	PFAM AMP-dependent synthetase and ligase
AB237_3254	COG0477	Major facilitator Superfamily
AB237_3255	COG2860	membrane
AB237_3257	COG1253	flavin adenine dinucleotide binding
AB237_3261	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AB237_3268	COG0655	NAD(P)H dehydrogenase (quinone) activity
AB237_3270	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AB237_3281	COG1309	transcriptional regulator
AB237_3287	COG0758	DNA mediated transformation
AB237_3289	COG0697	spore germination
AB237_3290	COG1309	transcriptional regulator
AB237_3293	COG0386	Belongs to the glutathione peroxidase family
AB237_3298	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AB237_3305	COG1121	(ABC) transporter
AB237_3306	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AB237_3307	COG1280	lysine exporter protein (LysE YggA)
AB237_3308	COG2837	iron assimilation
AB237_3310	COG0281	malic enzyme
AB237_3318	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AB237_3318	COG0519	Catalyzes the synthesis of GMP from XMP
AB237_3319	COG4399	Belongs to the UPF0754 family
AB237_3320	COG2259	Doxx family
AB237_3321	COG0586	Pfam SNARE associated Golgi protein
AB237_3323	COG1192	Involved in chromosome partitioning
AB237_3325	COG0271	Belongs to the BolA IbaG family
AB237_3329	COG2267	carboxylic ester hydrolase activity
AB237_3332	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AB237_3334	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AB237_3334	COG3321	synthase
AB237_3334	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AB237_3334	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AB237_3335	COG1960	acyl-CoA dehydrogenase activity
AB237_3337	COG2197	response regulator
AB237_3338	COG2197	response regulator
AB237_3340	COG3916	Acyl-homoserine-lactone synthase
AB237_3341	COG0477	Major facilitator Superfamily
AB237_3342	COG1024	Enoyl-CoA hydratase
AB237_3343	COG1024	Enoyl-CoA hydratase
AB237_3344	COG1960	acyl-CoA dehydrogenase activity
AB237_3345	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AB237_3349	COG1113	amino acid transport
AB237_3350	COG1113	amino acid transport
AB237_3353	COG1522	sequence-specific DNA binding
AB237_3358	COG0564	pseudouridine synthase activity
AB237_3368	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AB237_3371	COG1802	Transcriptional regulator
AB237_3372	COG1448	Aminotransferase
AB237_3373	COG0277	FAD linked oxidase domain protein
AB237_3375	COG2186	Transcriptional regulator
AB237_3377	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AB237_3381	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AB237_3382	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AB237_3383	COG1216	Glycosyl transferase, family 2
AB237_3386	COG0438	transferase activity, transferring glycosyl groups
AB237_3389	COG2030	dehydratase
AB237_3393	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AB237_3394	COG1596	polysaccharide export
AB237_3398	COG0728	peptidoglycan biosynthetic process
AB237_3399	COG3023	N-Acetylmuramoyl-L-alanine amidase
AB237_3410	COG0546	phosphoglycolate phosphatase activity
AB237_3411	COG1028	Short-chain dehydrogenase reductase Sdr
AB237_3415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AB237_3416	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AB237_3417	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB237_3418	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB237_3419	COG1116	anion transmembrane transporter activity
AB237_3420	COG1309	transcriptional regulator
AB237_3421	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AB237_3423	COG0196	riboflavin kinase activity
AB237_3424	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AB237_3437	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AB237_3441	COG0583	DNA-binding transcription factor activity
AB237_3447	COG2951	lytic endotransglycosylase activity
AB237_3448	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AB237_3451	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AB237_3453	COG0671	phosphoesterase, PA-phosphatase related
AB237_3454	COG0861	Integral membrane protein TerC family
AB237_3456	COG0754	glutathionylspermidine amidase activity
AB237_3458	COG0402	S-adenosylhomocysteine deaminase activity
AB237_3460	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AB237_3461	COG1230	cation diffusion facilitator family transporter