locus-tag	class	description
OC371_00010	COG0592	DNA-directed DNA polymerase activity
OC371_00020	COG0187	DNA topoisomerase II activity
OC371_00030	COG0586	Pfam SNARE associated Golgi protein
OC371_00035	COG0488	(ABC) transporter
OC371_00060	COG0596	Alpha beta hydrolase
OC371_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OC371_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OC371_00110	COG0733	neurotransmitter:sodium symporter activity
OC371_00120	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OC371_00145	COG0583	DNA-binding transcription factor activity
OC371_00150	COG2233	PERMEase
OC371_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OC371_00200	COG2814	Major facilitator Superfamily
OC371_00205	COG0656	L-ascorbic acid biosynthetic process
OC371_00210	COG0583	DNA-binding transcription factor activity
OC371_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OC371_00230	COG1064	alcohol dehydrogenase
OC371_00235	COG2818	Glycosylase
OC371_00250	COG1194	a g-specific adenine glycosylase
OC371_00260	COG0400	carboxylic ester hydrolase activity
OC371_00270	COG2983	Belongs to the UPF0260 family
OC371_00275	COG2133	pyrroloquinoline quinone binding
OC371_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OC371_00285	COG2116	formate transmembrane transporter activity
OC371_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OC371_00310	COG1335	isochorismatase
OC371_00315	COG0385	Bile acid
OC371_00320	COG0534	Mate efflux family protein
OC371_00325	COG1683	Conserved Protein
OC371_00345	COG0625	glutathione transferase activity
OC371_00355	COG1113	amino acid transport
OC371_00365	COG0523	cobalamin synthesis protein
OC371_00375	COG2188	Transcriptional regulator
OC371_00405	COG0010	Belongs to the arginase family
OC371_00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OC371_00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OC371_00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OC371_00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OC371_00485	COG0753	catalase activity
OC371_00545	COG0534	Mate efflux family protein
OC371_00550	COG0436	Aminotransferase
OC371_00555	COG2733	membrane
OC371_00570	COG2918	glutathione biosynthetic process
OC371_00600	COG4372	Transposase
OC371_00620	COG3150	esterase
OC371_00630	COG1028	Short-chain dehydrogenase reductase Sdr
OC371_00635	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
OC371_00645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OC371_00655	COG2233	PERMEase
OC371_00660	COG2351	hydroxyisourate hydrolase activity
OC371_00695	COG3706	GGDEF domain
OC371_00710	COG1393	Belongs to the ArsC family
OC371_00715	COG0708	Exodeoxyribonuclease III
OC371_00735	COG0189	ligase activity
OC371_00755	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OC371_00765	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OC371_00780	COG4942	peptidase
OC371_00790	COG0508	dehydrogenase complex catalyzes the overall conversion of
OC371_00800	COG2119	membrane
OC371_00805	COG4774	siderophore transport
OC371_00810	COG0426	domain, Protein
OC371_00810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OC371_00835	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OC371_00855	COG1902	pentaerythritol trinitrate reductase activity
OC371_00860	COG1519	Transferase
OC371_00865	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OC371_00870	COG0668	transmembrane transport
OC371_00880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OC371_00885	COG1335	isochorismatase
OC371_00890	COG1522	sequence-specific DNA binding
OC371_00915	COG2198	Histidine kinase
OC371_00915	COG0784	Response regulator, receiver
OC371_00915	COG2205	protein histidine kinase activity
OC371_00920	COG3162	membrane
OC371_00925	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OC371_00935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OC371_00955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OC371_00960	COG1309	transcriptional regulator
OC371_00980	COG0351	phosphomethylpyrimidine kinase
OC371_00980	COG0352	thiamine-phosphate diphosphorylase activity
OC371_00980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OC371_00990	COG2814	Major facilitator Superfamily
OC371_01005	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OC371_01015	COG1113	amino acid transport
OC371_01025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OC371_01030	COG1012	belongs to the aldehyde dehydrogenase family
OC371_01040	COG1335	isochorismatase
OC371_01055	COG4372	Transposase
OC371_01090	COG2814	Major facilitator Superfamily
OC371_01095	COG0583	DNA-binding transcription factor activity
OC371_01115	COG0667	Aldo Keto reductase
OC371_01150	COG1733	regulation of RNA biosynthetic process
OC371_01155	COG2249	NAD(P)H dehydrogenase (quinone) activity
OC371_01220	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OC371_01235	COG2329	Antibiotic biosynthesis monooxygenase
OC371_01265	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OC371_01295	COG0427	acetyl-CoA hydrolase
OC371_01320	COG0659	secondary active sulfate transmembrane transporter activity
OC371_01325	COG4221	oxidoreductase activity
OC371_01330	COG2873	o-acetylhomoserine
OC371_01335	COG0488	(ABC) transporter
OC371_01420	COG0833	amino acid
OC371_01465	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OC371_01470	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OC371_01485	COG2226	methyltransferase
OC371_01535	COG0067	glutamate synthase
OC371_01535	COG0069	glutamate synthase activity
OC371_01535	COG0070	glutamate synthase
OC371_01540	COG0493	'glutamate synthase
OC371_01550	COG1704	LemA family
OC371_01555	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OC371_01570	COG3307	-O-antigen
OC371_01590	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OC371_01605	COG0194	GDP metabolic process
OC371_01655	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OC371_01675	COG5380	lipid catabolic process
OC371_01680	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OC371_01705	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OC371_01710	COG0277	FAD linked oxidase domain protein
OC371_01720	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OC371_01725	COG2249	NAD(P)H dehydrogenase (quinone) activity
OC371_01740	COG1289	transmembrane transporter activity
OC371_01750	COG0628	permease
OC371_01755	COG1192	Involved in chromosome partitioning
OC371_01785	COG0833	amino acid
OC371_01790	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OC371_01795	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OC371_01805	COG1012	belongs to the aldehyde dehydrogenase family
OC371_01845	COG0583	DNA-binding transcription factor activity
OC371_01895	COG0517	IMP dehydrogenase activity
OC371_01900	COG1983	PspC domain protein
OC371_01910	COG1960	acyl-CoA dehydrogenase activity
OC371_01925	COG0408	coproporphyrinogen oxidase activity
OC371_01945	COG0513	Belongs to the DEAD box helicase family
OC371_01955	COG1127	ABC transporter
OC371_01960	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OC371_01970	COG2854	intermembrane phospholipid transfer
OC371_01980	COG0598	Magnesium transport protein CorA
OC371_01990	COG0494	nUDIX hydrolase
OC371_01995	COG1040	competence protein
OC371_02000	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OC371_02020	COG1946	Acyl-CoA thioesterase
OC371_02025	COG1301	dicarboxylic acid transport
OC371_02040	COG1959	2 iron, 2 sulfur cluster binding
OC371_02045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OC371_02045	COG1017	nitric oxide dioxygenase activity
OC371_02050	COG0433	COG0433 Predicted ATPase
OC371_02055	COG0626	cystathionine gamma-synthase activity
OC371_02210	COG1960	acyl-CoA dehydrogenase activity
OC371_02215	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
OC371_02245	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
OC371_02250	COG0339	signal peptide processing
OC371_02255	COG0557	exoribonuclease II activity
OC371_02300	COG0179	Fumarylacetoacetate (FAA) hydrolase
OC371_02305	COG2169	Transcriptional regulator
OC371_02310	COG0697	spore germination
OC371_02315	COG1295	ribonuclease BN
OC371_02350	COG1702	phosphate starvation-inducible protein PhoH
OC371_02360	COG0739	heme binding
OC371_02360	COG0741	lytic transglycosylase activity
OC371_02360	COG1196	nuclear chromosome segregation
OC371_02390	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OC371_02395	COG1183	phosphatidylcholine synthase activity
OC371_02440	COG1960	acyl-CoA dehydrogenase activity
OC371_02445	COG1309	transcriptional regulator
OC371_02460	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OC371_02465	COG1960	acyl-CoA dehydrogenase activity
OC371_02485	COG2969	positive regulation of protein catabolic process
OC371_02495	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OC371_02510	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OC371_02515	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OC371_02535	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OC371_02545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OC371_02550	COG1408	metallophosphoesterase
OC371_02565	COG2199	diguanylate cyclase activity
OC371_02625	COG1607	acyl-coa hydrolase
OC371_02655	COG2350	Protein conserved in bacteria
OC371_02665	COG0613	PHP domain protein
OC371_02670	COG3781	membrane
OC371_02680	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OC371_02685	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OC371_02695	COG1862	Preprotein translocase
OC371_02725	COG2205	protein histidine kinase activity
OC371_02730	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OC371_02750	COG0726	polysaccharide deacetylase
OC371_02755	COG0463	Glycosyl transferase, family 2
OC371_02760	COG0438	transferase activity, transferring glycosyl groups
OC371_02830	COG1960	acyl-CoA dehydrogenase activity
OC371_02835	COG1960	acyl-CoA dehydrogenase activity
OC371_02845	COG2205	protein histidine kinase activity
OC371_02850	COG0745	RESPONSE REGULATOR receiver
OC371_02855	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OC371_02870	COG0584	glycerophosphoryl diester phosphodiesterase
OC371_02875	COG2096	Adenosyltransferase
OC371_02925	COG0285	dihydrofolate synthase activity
OC371_02945	COG0450	alkyl hydroperoxide reductase
OC371_02960	COG0477	Major facilitator Superfamily
OC371_02965	COG1272	protein, Hemolysin III
OC371_02995	COG0183	Belongs to the thiolase family
OC371_03000	COG2207	Transcriptional regulator
OC371_03020	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OC371_03040	COG0183	Belongs to the thiolase family
OC371_03050	COG2885	chlorophyll binding
OC371_03050	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
OC371_03060	COG1690	Belongs to the RtcB family
OC371_03065	COG0833	amino acid
OC371_03075	COG2233	PERMEase
OC371_03080	COG1217	gtp-binding protein TYPA
OC371_03105	COG2094	Belongs to the DNA glycosylase MPG family
OC371_03115	COG1902	pentaerythritol trinitrate reductase activity
OC371_03130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OC371_03135	COG0354	folic acid binding
OC371_03145	COG3189	MarR family transcriptional regulator
OC371_03150	COG2824	Alkylphosphonate utilization operon protein PhnA
OC371_03155	COG3422	double-strand break repair
OC371_03195	COG0840	transmembrane signaling receptor activity
OC371_03215	COG5510	response to toxic substance
OC371_03225	COG2832	Protein of unknown function (DUF454)
OC371_03230	COG1376	ErfK ybiS ycfS ynhG family protein
OC371_03270	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OC371_03280	COG1289	transmembrane transporter activity
OC371_03285	COG2814	Major facilitator Superfamily
OC371_03305	COG1115	amino acid carrier protein
OC371_03310	COG1752	Esterase of the alpha-beta hydrolase superfamily
OC371_03315	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OC371_03320	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
OC371_03350	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OC371_03360	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OC371_03365	COG1077	Cell shape determining protein MreB Mrl
OC371_03370	COG1792	Involved in formation and maintenance of cell shape
OC371_03375	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
OC371_03380	COG0424	maF-like protein
OC371_03385	COG1530	ribonuclease E activity
OC371_03395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OC371_03415	COG2249	NAD(P)H dehydrogenase (quinone) activity
OC371_03440	COG2207	Transcriptional regulator
OC371_03460	COG1113	amino acid transport
OC371_03465	COG2828	Protein conserved in bacteria
OC371_03470	COG0142	geranyltranstransferase activity
OC371_03475	COG2315	Protein conserved in bacteria
OC371_03490	COG1752	Esterase of the alpha-beta hydrolase superfamily
OC371_03510	COG2194	sulfuric ester hydrolase activity
OC371_03515	COG0745	RESPONSE REGULATOR receiver
OC371_03520	COG0642	Histidine kinase
OC371_03530	COG0004	ammonium transporteR
OC371_03535	COG0583	DNA-binding transcription factor activity
OC371_03555	COG0525	valine-tRNA ligase activity
OC371_03565	COG1028	Short-chain dehydrogenase reductase Sdr
OC371_03575	COG0393	Putative heavy-metal-binding
OC371_03580	COG0393	Putative heavy-metal-binding
OC371_03585	COG1538	Outer membrane efflux protein
OC371_03595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OC371_03600	COG0671	phosphoesterase, PA-phosphatase related
OC371_03630	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OC371_03645	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OC371_03645	COG1648	precorrin-2 dehydrogenase activity
OC371_03650	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OC371_03655	COG1733	regulation of RNA biosynthetic process
OC371_03665	COG0531	amino acid
OC371_03680	COG0321	lipoyl(octanoyl) transferase activity
OC371_03685	COG2921	Belongs to the UPF0250 family
OC371_03725	COG2009	succinate dehydrogenase
OC371_03730	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OC371_03735	COG1053	succinate dehydrogenase
OC371_03740	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OC371_03765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OC371_03785	COG2354	Protein conserved in bacteria
OC371_03790	COG2321	neutral zinc metallopeptidase
OC371_03815	COG2843	Capsule synthesis protein
OC371_03830	COG0589	response to stress
OC371_03850	COG0505	Belongs to the CarA family
OC371_03875	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OC371_03880	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OC371_03930	COG0477	Major facilitator Superfamily
OC371_03935	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OC371_03950	COG1597	lipid kinase activity
OC371_03955	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OC371_03980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OC371_03985	COG0584	glycerophosphoryl diester phosphodiesterase
OC371_04005	COG0741	lytic transglycosylase activity
OC371_04025	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OC371_04040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OC371_04070	COG0778	Nitroreductase
OC371_04085	COG1929	Belongs to the glycerate kinase type-1 family
OC371_04090	COG0243	molybdopterin cofactor binding
OC371_04095	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OC371_04100	COG3339	Conserved Protein
OC371_04110	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
OC371_04125	COG1113	amino acid transport
OC371_04135	COG0019	diaminopimelate decarboxylase activity
OC371_04145	COG1280	lysine exporter protein (LysE YggA)
OC371_04150	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OC371_04180	COG0463	Glycosyl transferase, family 2
OC371_04200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OC371_04235	COG4591	ABC-type transport system involved in lipoprotein release permease component
OC371_04240	COG1136	(ABC) transporter
OC371_04245	COG2333	competence protein COMEC
OC371_04245	COG0658	competence protein
OC371_04255	COG0616	signal peptide processing
OC371_04255	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OC371_04260	COG0596	Alpha beta hydrolase
OC371_04265	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OC371_04275	COG0628	permease
OC371_04310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OC371_04330	COG0823	Involved in the tonB-independent uptake of proteins
OC371_04350	COG0824	Thioesterase
OC371_04355	COG1473	amidohydrolase
OC371_04375	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OC371_04375	COG0047	phosphoribosylformylglycinamidine synthase activity
OC371_04380	COG2814	Major facilitator Superfamily
OC371_04395	COG1024	Enoyl-CoA hydratase
OC371_04400	COG1056	cytidyltransferase-related domain
OC371_04400	COG1051	belongs to the nudix hydrolase family
OC371_04410	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OC371_04425	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OC371_04440	COG4625	pathogenesis
OC371_04445	COG0583	DNA-binding transcription factor activity
OC371_04450	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
OC371_04455	COG4208	sulfate ABC transporter
OC371_04460	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OC371_04470	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
OC371_04475	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OC371_04480	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OC371_04500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OC371_04515	COG0681	Belongs to the peptidase S26 family
OC371_04530	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OC371_04540	COG1381	Involved in DNA repair and RecF pathway recombination
OC371_04545	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OC371_04555	COG4221	oxidoreductase activity
OC371_04585	COG0436	Aminotransferase
OC371_04605	COG0556	nucleotide-excision repair
OC371_04660	COG2070	2-Nitropropane dioxygenase
OC371_04690	COG1215	transferase activity, transferring glycosyl groups
OC371_04705	COG0415	Belongs to the DNA photolyase family
OC371_04715	COG1252	NADH dehydrogenase
OC371_04720	COG1686	Belongs to the peptidase S11 family
OC371_04735	COG1187	pseudouridine synthase activity
OC371_04760	COG0477	Major facilitator Superfamily
OC371_04765	COG0583	DNA-binding transcription factor activity
OC371_04770	COG1823	symporter activity
OC371_04780	COG0612	Peptidase, M16
OC371_04805	COG0352	thiamine-phosphate diphosphorylase activity
OC371_04840	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OC371_04855	COG1309	transcriptional regulator
OC371_04865	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OC371_04870	COG0076	glutamate decarboxylase activity
OC371_04880	COG1522	sequence-specific DNA binding
OC371_04885	COG3961	Belongs to the TPP enzyme family
OC371_04890	COG1113	amino acid transport
OC371_04895	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OC371_04900	COG0573	inorganic phosphate transmembrane transporter activity
OC371_04910	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OC371_04915	COG0616	signal peptide processing
OC371_04950	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OC371_04955	COG1686	Belongs to the peptidase S11 family
OC371_04980	COG0583	DNA-binding transcription factor activity
OC371_04985	COG1067	ATP-dependent peptidase activity
OC371_05030	COG1966	Carbon starvation protein
OC371_05035	COG2879	small protein
OC371_05070	COG2508	Transcriptional regulator
OC371_05070	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OC371_05090	COG1113	amino acid transport
OC371_05095	COG0583	DNA-binding transcription factor activity
OC371_05100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OC371_05110	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OC371_05120	COG1012	belongs to the aldehyde dehydrogenase family
OC371_05130	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OC371_05135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OC371_05135	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
OC371_05170	COG2814	Major facilitator Superfamily
OC371_05175	COG4948	Mandelate Racemase Muconate Lactonizing
OC371_05185	COG1309	transcriptional regulator
OC371_05205	COG1741	Belongs to the pirin family
OC371_05215	COG2964	Protein conserved in bacteria
OC371_05230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OC371_05240	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OC371_05245	COG4605	iron ion homeostasis
OC371_05250	COG4604	ABC transporter, ATP-binding protein
OC371_05255	COG4607	ABC-type enterochelin transport system periplasmic component
OC371_05260	COG4774	siderophore transport
OC371_05275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OC371_05280	COG1021	2,3-dihydroxybenzoate-AMP ligase
OC371_05285	COG1535	isochorismatase
OC371_05285	COG3433	isochorismatase activity
OC371_05295	COG1132	(ABC) transporter
OC371_05300	COG1132	(ABC) transporter
OC371_05305	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
OC371_05315	COG1169	isochorismate synthase
OC371_05330	COG3739	integral membrane protein
OC371_05355	COG0302	gtp cyclohydrolase
OC371_05365	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OC371_05395	COG0308	aminopeptidase N
OC371_05400	COG0512	Glutamine amidotransferase of anthranilate synthase
OC371_05465	COG3620	sequence-specific DNA binding
OC371_05540	COG2826	transposase and inactivated derivatives, IS30 family
OC371_05595	COG4372	Transposase
OC371_05770	COG4372	Transposase
OC371_05915	COG3620	sequence-specific DNA binding
OC371_05990	COG2826	transposase and inactivated derivatives, IS30 family
OC371_06045	COG4372	Transposase
OC371_06220	COG4372	Transposase
OC371_06300	COG0582	viral genome integration into host DNA
OC371_06315	COG0174	glutamine synthetase
OC371_06325	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OC371_06360	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OC371_06365	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OC371_06370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OC371_06390	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OC371_06395	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OC371_06400	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OC371_06415	COG1960	acyl-CoA dehydrogenase activity
OC371_06420	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OC371_06425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OC371_06435	COG2223	nitrite transmembrane transporter activity
OC371_06445	COG0024	Methionine aminopeptidase
OC371_06450	COG0052	Belongs to the universal ribosomal protein uS2 family
OC371_06465	COG2207	Transcriptional regulator
OC371_06490	COG2951	lytic endotransglycosylase activity
OC371_06495	COG0772	Belongs to the SEDS family
OC371_06510	COG0842	Transport permease protein
OC371_06515	COG1131	(ABC) transporter
OC371_06560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OC371_06575	COG4215	(ABC) transporter
OC371_06580	COG4160	amino acid transport
OC371_06585	COG4598	ABC transporter
OC371_06595	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OC371_06600	COG0826	peptidase U32
OC371_06605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OC371_06620	COG1720	tRNA m6t6A37 methyltransferase activity
OC371_06630	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OC371_06645	COG0642	Histidine kinase
OC371_06655	COG0494	nUDIX hydrolase
OC371_06665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OC371_06670	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OC371_06675	COG3139	Protein of unknown function (DUF1315)
OC371_06680	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OC371_06685	COG1301	dicarboxylic acid transport
OC371_06690	COG1960	acyl-CoA dehydrogenase activity
OC371_06695	COG2819	hydrolase of the alpha beta superfamily
OC371_06705	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OC371_06715	COG2195	Cleaves the N-terminal amino acid of tripeptides
OC371_06720	COG1234	tRNA 3'-trailer cleavage
OC371_06750	COG2363	Small membrane protein
OC371_06775	COG0513	Belongs to the DEAD box helicase family
OC371_06785	COG0778	Nitroreductase
OC371_06815	COG1286	toxin biosynthetic process
OC371_06840	COG4783	chaperone-mediated protein folding
OC371_06845	COG1610	YqeY-like protein
OC371_06945	COG3111	PFAM Bacterial OB fold (BOF) protein
OC371_06970	COG3243	poly(R)-hydroxyalkanoic acid synthase
OC371_06975	COG0786	glutamate:sodium symporter activity
OC371_06985	COG2186	Transcriptional regulator
OC371_06995	COG2826	transposase and inactivated derivatives, IS30 family
OC371_07040	COG0477	Major facilitator Superfamily
OC371_07070	COG2985	domain, Protein
OC371_07080	COG2995	paraquat-inducible protein a
OC371_07085	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OC371_07085	COG3008	intermembrane lipid transfer
OC371_07095	COG1794	racemase activity, acting on amino acids and derivatives
OC371_07125	COG1301	dicarboxylic acid transport
OC371_07135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OC371_07140	COG2011	ABC-type metal ion transport system permease component
OC371_07145	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OC371_07150	COG1464	Belongs to the NlpA lipoprotein family
OC371_07155	COG0151	Belongs to the GarS family
OC371_07160	COG0138	bifunctional purine biosynthesis protein purh
OC371_07165	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
OC371_07195	COG2308	Evidence 4 Homologs of previously reported genes of
OC371_07205	COG1305	Transglutaminase-like
OC371_07215	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OC371_07220	COG0305	Participates in initiation and elongation during chromosome replication
OC371_07245	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OC371_07255	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OC371_07260	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OC371_07285	COG1649	PFAM Uncharacterised BCR, COG1649
OC371_07285	COG0726	polysaccharide deacetylase
OC371_07290	COG1215	transferase activity, transferring glycosyl groups
OC371_07295	COG3658	cytochrome
OC371_07305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OC371_07320	COG0583	DNA-binding transcription factor activity
OC371_07340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OC371_07345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OC371_07360	COG1960	acyl-CoA dehydrogenase activity
OC371_07365	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OC371_07370	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OC371_07395	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
OC371_07400	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OC371_07410	COG2205	protein histidine kinase activity
OC371_07415	COG0745	RESPONSE REGULATOR receiver
OC371_07420	COG0174	glutamine synthetase
OC371_07440	COG0729	surface antigen
OC371_07465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OC371_07470	COG2814	Major facilitator Superfamily
OC371_07495	COG0583	DNA-binding transcription factor activity
OC371_07510	COG1187	pseudouridine synthase activity
OC371_07530	COG0802	atpase or kinase
OC371_07535	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OC371_07545	COG1923	regulation of RNA biosynthetic process
OC371_07550	COG0697	spore germination
OC371_07565	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OC371_07575	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OC371_07595	COG4302	ethanolamine ammonia-lyase activity
OC371_07600	COG4303	Ethanolamine ammonia lyase large subunit
OC371_07605	COG0531	amino acid
OC371_07625	COG1454	alcohol dehydrogenase
OC371_07630	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OC371_07640	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
OC371_07660	COG0308	aminopeptidase N
OC371_07670	COG4221	oxidoreductase activity
OC371_07680	COG1605	Chorismate mutase
OC371_07700	COG1309	transcriptional regulator
OC371_07710	COG0668	transmembrane transport
OC371_07720	COG2826	transposase and inactivated derivatives, IS30 family
OC371_07755	COG4773	Receptor
OC371_07775	COG0488	(ABC) transporter
OC371_07780	COG0589	response to stress
OC371_07805	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OC371_07815	COG3135	benzoate transporter
OC371_07820	COG1522	sequence-specific DNA binding
OC371_07830	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OC371_07835	COG0583	DNA-binding transcription factor activity
OC371_07845	COG0183	Belongs to the thiolase family
OC371_07855	COG2030	dehydratase
OC371_07860	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OC371_07875	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OC371_07885	COG0824	Thioesterase
OC371_07890	COG1454	alcohol dehydrogenase
OC371_07900	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OC371_07920	COG0069	glutamate synthase activity
OC371_08065	COG5410	chromosome segregation
OC371_08105	COG4372	Transposase
OC371_08180	COG1598	PFAM Uncharacterised protein family UPF0150
OC371_08195	COG2194	sulfuric ester hydrolase activity
OC371_08200	COG2814	Major facilitator Superfamily
OC371_08215	COG0511	ligase activity, forming carbon-carbon bonds
OC371_08230	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OC371_08230	COG1116	anion transmembrane transporter activity
OC371_08285	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OC371_08285	COG2146	nitrite reductase [NAD(P)H] activity
OC371_08290	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OC371_08295	COG0243	molybdopterin cofactor binding
OC371_08305	COG0243	molybdopterin cofactor binding
OC371_08310	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OC371_08325	COG0315	cyclic pyranopterin monophosphate synthase activity
OC371_08325	COG0521	Mo-molybdopterin cofactor biosynthetic process
OC371_08330	COG0303	'Molybdopterin
OC371_08340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OC371_08345	COG0697	spore germination
OC371_08365	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
OC371_08370	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OC371_08425	COG2204	response regulator
OC371_08430	COG3852	Histidine kinase
OC371_08450	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OC371_08455	COG0575	Belongs to the CDS family
OC371_08490	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OC371_08505	COG2137	regulation of response to DNA damage stimulus
OC371_08515	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OC371_08520	COG1011	Hydrolase
OC371_08545	COG1522	sequence-specific DNA binding
OC371_08555	COG1113	amino acid transport
OC371_08575	COG0659	secondary active sulfate transmembrane transporter activity
OC371_08580	COG2135	peptidase activity
OC371_08595	COG5001	Diguanylate cyclase
OC371_08595	COG3300	MHYT domain
OC371_08615	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OC371_08615	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
OC371_08615	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OC371_08620	COG1105	Belongs to the carbohydrate kinase PfkB family
OC371_08625	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OC371_08625	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OC371_08655	COG0024	Methionine aminopeptidase
OC371_08660	COG0583	DNA-binding transcription factor activity
OC371_08670	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OC371_08675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OC371_08680	COG0516	GMP reductase activity
OC371_08680	COG0517	IMP dehydrogenase activity
OC371_08705	COG0552	protein localization to endoplasmic reticulum
OC371_08715	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
OC371_08730	COG4890	Cyd operon protein YbgT
OC371_08735	COG1294	oxidase, subunit
OC371_08750	COG1585	Membrane protein implicated in regulation of membrane protease activity
OC371_08760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OC371_08765	COG4774	siderophore transport
OC371_08780	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OC371_08785	COG0569	domain protein
OC371_08790	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OC371_08820	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OC371_08825	COG0542	response to heat
OC371_08850	COG0446	pyridine nucleotide-disulphide oxidoreductase
OC371_08850	COG1902	pentaerythritol trinitrate reductase activity
OC371_08900	COG2323	membrane
OC371_08905	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OC371_08915	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OC371_08920	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OC371_08925	COG0183	Belongs to the thiolase family
OC371_08930	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OC371_08935	COG0596	Alpha beta hydrolase
OC371_08940	COG2271	Major facilitator Superfamily
OC371_08945	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OC371_08950	COG3485	protocatechuate 3,4-dioxygenase
OC371_08955	COG3485	protocatechuate 3,4-dioxygenase
OC371_08960	COG0710	3-dehydroquinate dehydratase activity
OC371_08965	COG3420	alginic acid biosynthetic process
OC371_08970	COG3659	wide pore channel activity
OC371_08975	COG4993	Dehydrogenase
OC371_08985	COG2391	methyltransferase activity
OC371_09000	COG1414	Transcriptional regulator
OC371_09005	COG0583	DNA-binding transcription factor activity
OC371_09010	COG1960	acyl-CoA dehydrogenase activity
OC371_09035	COG2814	Major facilitator Superfamily
OC371_09045	COG0154	amidase activity
OC371_09065	COG4638	Rieske (2fe-2S)
OC371_09075	COG1028	Short-chain dehydrogenase reductase Sdr
OC371_09085	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OC371_09095	COG3733	amine oxidase
OC371_09105	COG1012	belongs to the aldehyde dehydrogenase family
OC371_09115	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OC371_09120	COG0183	Belongs to the thiolase family
OC371_09125	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OC371_09130	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OC371_09140	COG4829	muconolactone delta-isomerase
OC371_09145	COG4948	Mandelate Racemase Muconate Lactonizing
OC371_09150	COG0583	DNA-binding transcription factor activity
OC371_09160	COG2186	Transcriptional regulator
OC371_09180	COG1012	belongs to the aldehyde dehydrogenase family
OC371_09200	COG1960	acyl-CoA dehydrogenase activity
OC371_09205	COG1028	Short-chain dehydrogenase reductase Sdr
OC371_09210	COG3829	transcription factor binding
OC371_09220	COG3162	membrane
OC371_09235	COG1012	belongs to the aldehyde dehydrogenase family
OC371_09250	COG0753	catalase activity
OC371_09270	COG1846	Transcriptional regulator
OC371_09275	COG1902	pentaerythritol trinitrate reductase activity
OC371_09275	COG0446	pyridine nucleotide-disulphide oxidoreductase
OC371_09285	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OC371_09315	COG1309	transcriptional regulator
OC371_09330	COG1335	isochorismatase
OC371_09335	COG0583	DNA-binding transcription factor activity
OC371_09345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OC371_09345	COG0475	glutathione-regulated potassium exporter activity
OC371_09355	COG1473	amidohydrolase
OC371_09365	COG2831	hemolysin activation secretion protein
OC371_09370	COG3210	domain, Protein
OC371_09400	COG2188	Transcriptional regulator
OC371_09415	COG0583	DNA-binding transcription factor activity
OC371_09445	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OC371_09475	COG1566	PFAM secretion protein HlyD family protein
OC371_09490	COG1012	belongs to the aldehyde dehydrogenase family
OC371_09495	COG0129	dihydroxy-acid dehydratase activity
OC371_09505	COG0583	DNA-binding transcription factor activity
OC371_09510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OC371_09520	COG2084	Dehydrogenase
OC371_09525	COG2207	Transcriptional regulator
OC371_09540	COG1064	alcohol dehydrogenase
OC371_09550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OC371_09555	COG1120	ATPase activity
OC371_09575	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OC371_09695	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OC371_09745	COG1028	Short-chain dehydrogenase reductase Sdr
OC371_09760	COG2207	Transcriptional regulator
OC371_09770	COG2205	protein histidine kinase activity
OC371_09775	COG0745	RESPONSE REGULATOR receiver
OC371_09785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OC371_09790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OC371_09795	COG1538	Outer membrane efflux protein
OC371_09805	COG2072	flavoprotein involved in K transport
OC371_09825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OC371_09905	COG3539	Fimbrial protein
OC371_09930	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
OC371_09940	COG0753	catalase activity
OC371_09960	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OC371_10030	COG3433	isochorismatase activity
OC371_10030	COG1535	isochorismatase
OC371_10035	COG1028	Short-chain dehydrogenase reductase Sdr
OC371_10040	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OC371_10045	COG4149	molybdate abc transporter
OC371_10050	COG0725	ABC transporter, periplasmic molybdate-binding protein
OC371_10060	COG4638	Rieske (2fe-2S)
OC371_10065	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
OC371_10070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OC371_10070	COG0543	2 iron, 2 sulfur cluster binding
OC371_10095	COG1028	Short-chain dehydrogenase reductase Sdr
OC371_10110	COG2207	Transcriptional regulator
OC371_10115	COG1028	Short-chain dehydrogenase reductase Sdr
OC371_10120	COG2610	gluconate transmembrane transporter activity
OC371_10130	COG0583	DNA-binding transcription factor activity
OC371_10140	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OC371_10145	COG2031	fatty acid transporter
OC371_10150	COG0183	Belongs to the thiolase family
OC371_10155	COG0583	DNA-binding transcription factor activity
OC371_10160	COG0583	DNA-binding transcription factor activity
OC371_10175	COG1027	Aspartate ammonia-lyase
OC371_10185	COG0477	Major facilitator Superfamily
OC371_10205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OC371_10210	COG4521	taurine ABC transporter
OC371_10225	COG2188	Transcriptional regulator
OC371_10235	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OC371_10240	COG1733	regulation of RNA biosynthetic process
OC371_10245	COG2207	Transcriptional regulator
OC371_10245	COG3708	Transcriptional regulator
OC371_10260	COG0730	response to heat
OC371_10275	COG3453	Protein conserved in bacteria
OC371_10275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OC371_10285	COG3781	membrane
OC371_10290	COG1063	alcohol dehydrogenase
OC371_10300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OC371_10305	COG0508	dehydrogenase complex catalyzes the overall conversion of
OC371_10310	COG0022	dehydrogenase e1 component
OC371_10315	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OC371_10320	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OC371_10350	COG0133	tryptophan synthase activity
OC371_10360	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OC371_10395	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OC371_10420	COG2226	methyltransferase
OC371_10475	COG0842	Transport permease protein
OC371_10480	COG0842	Transport permease protein
OC371_10485	COG1131	(ABC) transporter
OC371_10510	COG4372	Transposase
OC371_10520	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OC371_10525	COG4773	Receptor
OC371_10545	COG0730	response to heat
OC371_10550	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OC371_10570	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OC371_10585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OC371_10625	COG4264	IucA IucC family
OC371_10630	COG4264	IucA IucC family
OC371_10650	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OC371_10665	COG1960	acyl-CoA dehydrogenase activity
OC371_10670	COG1960	acyl-CoA dehydrogenase activity
OC371_10675	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OC371_10680	COG2207	Transcriptional regulator
OC371_10685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OC371_10690	COG0776	regulation of translation
OC371_10715	COG0822	iron-sulfur transferase activity
OC371_10720	COG0316	Belongs to the HesB IscA family
OC371_10750	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OC371_10770	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OC371_10775	COG0702	epimerase
OC371_10810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OC371_10820	COG0339	signal peptide processing
OC371_10870	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OC371_10930	COG1196	nuclear chromosome segregation
OC371_10930	COG0739	heme binding
OC371_10930	COG0741	lytic transglycosylase activity
OC371_10990	COG4695	Portal protein
OC371_11075	COG0305	Participates in initiation and elongation during chromosome replication
OC371_11140	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OC371_11170	COG0776	regulation of translation
OC371_11235	COG0084	hydrolase, TatD family'
OC371_11255	COG1663	tetraacyldisaccharide 4'-kinase activity
OC371_11260	COG1132	(ABC) transporter
OC371_11270	COG0811	peptide transport
OC371_11275	COG1475	DNA binding
OC371_11280	COG1192	Involved in chromosome partitioning
OC371_11290	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OC371_11305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OC371_11310	COG0191	fructose-bisphosphate aldolase activity
OC371_11330	COG0424	maF-like protein
OC371_11335	COG2850	peptidyl-arginine hydroxylation
OC371_11345	COG0640	Transcriptional regulator
OC371_11355	COG3619	membrane
OC371_11360	COG3122	Protein conserved in bacteria
OC371_11365	COG1132	(ABC) transporter
OC371_11385	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OC371_11390	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OC371_11400	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OC371_11400	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OC371_11400	COG0506	proline dehydrogenase activity
OC371_11405	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OC371_11420	COG3698	Phosphodiester glycosidase
OC371_11430	COG2353	YceI-like domain
OC371_11440	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OC371_11490	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OC371_11490	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OC371_11515	COG3539	Fimbrial protein
OC371_11520	COG3121	Chaperone
OC371_11545	COG0697	spore germination
OC371_11555	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OC371_11565	COG0583	DNA-binding transcription factor activity
OC371_11595	COG1309	transcriptional regulator
OC371_11610	COG1522	sequence-specific DNA binding
OC371_11620	COG1126	abc transporter atp-binding protein
OC371_11625	COG0765	amino acid transport
OC371_11630	COG0765	amino acid transport
OC371_11660	COG1464	Belongs to the NlpA lipoprotein family
OC371_11670	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OC371_11675	COG2011	ABC-type metal ion transport system permease component
OC371_11680	COG0012	GTP binding
OC371_11705	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OC371_11745	COG0386	Belongs to the glutathione peroxidase family
OC371_11755	COG0436	Aminotransferase
OC371_11795	COG3634	alkyl hydroperoxide reductase activity
OC371_11810	COG0583	DNA-binding transcription factor activity
OC371_11815	COG0798	PFAM Bile acid sodium symporter
OC371_11820	COG0640	Transcriptional regulator
OC371_11835	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OC371_11845	COG0583	DNA-binding transcription factor activity
OC371_11855	COG1953	Uracil, thiamine, allantoin
OC371_11865	COG2175	clavaminate synthase activity
OC371_11870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OC371_11875	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
OC371_11880	COG4521	taurine ABC transporter
OC371_11890	COG4372	Transposase
OC371_11905	COG0477	Major facilitator Superfamily
OC371_11925	COG1271	oxidase subunit
OC371_11930	COG1294	oxidase, subunit
OC371_11940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OC371_11960	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OC371_11980	COG3052	prosthetic group binding
OC371_11985	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
OC371_11995	COG2814	Major facilitator Superfamily
OC371_12015	COG1346	cytolysis
OC371_12025	COG0583	DNA-binding transcription factor activity
OC371_12030	COG0625	glutathione transferase activity
OC371_12035	COG0625	glutathione transferase activity
OC371_12040	COG0583	DNA-binding transcription factor activity
OC371_12055	COG1045	serine acetyltransferase
OC371_12060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OC371_12065	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OC371_12075	COG1280	lysine exporter protein (LysE YggA)
OC371_12090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OC371_12095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OC371_12100	COG1126	abc transporter atp-binding protein
OC371_12105	COG0765	amino acid transport
OC371_12110	COG0765	amino acid transport
OC371_12130	COG0784	Response regulator, receiver
OC371_12130	COG2205	protein histidine kinase activity
OC371_12150	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OC371_12170	COG1028	Short-chain dehydrogenase reductase Sdr
OC371_12220	COG0583	DNA-binding transcription factor activity
OC371_12240	COG0318	PFAM AMP-dependent synthetase and ligase
OC371_12245	COG1309	transcriptional regulator
OC371_12250	COG1960	acyl-CoA dehydrogenase activity
OC371_12255	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OC371_12260	COG1024	Enoyl-CoA hydratase
OC371_12265	COG4770	biotin carboxylase activity
OC371_12275	COG0583	DNA-binding transcription factor activity
OC371_12290	COG1960	acyl-CoA dehydrogenase activity
OC371_12300	COG2814	Major facilitator Superfamily
OC371_12310	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OC371_12315	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OC371_12320	COG2814	Major facilitator Superfamily
OC371_12325	COG1960	acyl-CoA dehydrogenase activity
OC371_12330	COG1024	Enoyl-CoA hydratase
OC371_12335	COG1028	Short-chain dehydrogenase reductase Sdr
OC371_12340	COG1250	3-hydroxyacyl-CoA dehydrogenase
OC371_12345	COG0183	Belongs to the thiolase family
OC371_12355	COG2814	Major facilitator Superfamily
OC371_12365	COG1024	Enoyl-CoA hydratase
OC371_12380	COG1960	acyl-CoA dehydrogenase activity
OC371_12385	COG2814	Major facilitator Superfamily
OC371_12390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OC371_12395	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OC371_12410	COG3842	ATPase activity
OC371_12415	COG1840	ABC-type Fe3 transport system, periplasmic component
OC371_12425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OC371_12430	COG1414	Transcriptional regulator
OC371_12440	COG0583	DNA-binding transcription factor activity
OC371_12445	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OC371_12450	COG1012	belongs to the aldehyde dehydrogenase family
OC371_12460	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OC371_12470	COG1012	belongs to the aldehyde dehydrogenase family
OC371_12475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OC371_12480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OC371_12485	COG2267	carboxylic ester hydrolase activity
OC371_12505	COG3038	cytochrome b561
OC371_12510	COG0753	catalase activity
OC371_12545	COG2050	protein possibly involved in aromatic compounds catabolism
OC371_12555	COG3327	negative regulation of DNA-templated transcription, initiation
OC371_12560	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
OC371_12565	COG0183	Belongs to the thiolase family
OC371_12570	COG1250	3-hydroxyacyl-CoA dehydrogenase
OC371_12575	COG1024	Enoyl-CoA hydratase
OC371_12580	COG1024	Enoyl-CoA hydratase
OC371_12585	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OC371_12590	COG2151	metal-sulfur cluster biosynthetic enzyme
OC371_12595	COG3396	Phenylacetate-CoA oxygenase
OC371_12600	COG3460	Phenylacetate-CoA oxygenase
OC371_12605	COG3396	Phenylacetate-CoA oxygenase
OC371_12610	COG2030	dehydratase
OC371_12610	COG1012	belongs to the aldehyde dehydrogenase family
OC371_12615	COG1760	l-serine dehydratase
OC371_12620	COG0531	amino acid
OC371_12625	COG1012	belongs to the aldehyde dehydrogenase family
OC371_12640	COG0446	pyridine nucleotide-disulphide oxidoreductase
OC371_12650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OC371_12670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OC371_12680	COG0789	Transcriptional regulator
OC371_12690	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OC371_12705	COG2807	transmembrane transport
OC371_12710	COG0590	tRNA wobble adenosine to inosine editing
OC371_12830	COG1116	anion transmembrane transporter activity
OC371_12835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OC371_12845	COG0864	Transcriptional regulator
OC371_12865	COG2249	NAD(P)H dehydrogenase (quinone) activity
OC371_12870	COG0439	Biotin carboxylase
OC371_12895	COG1063	alcohol dehydrogenase
OC371_12905	COG1309	transcriptional regulator
OC371_12925	COG0038	chloride channel
OC371_12930	COG4770	biotin carboxylase activity
OC371_12950	COG1914	H( )-stimulated, divalent metal cation uptake system
OC371_12955	COG0583	DNA-binding transcription factor activity
OC371_13005	COG1250	3-hydroxyacyl-CoA dehydrogenase
OC371_13025	COG2814	Major facilitator Superfamily
OC371_13040	COG1560	Kdo2-lipid A biosynthetic process
OC371_13050	COG5006	permease, DMT superfamily
OC371_13055	COG1522	sequence-specific DNA binding
OC371_13070	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OC371_13080	COG4122	O-methyltransferase activity
OC371_13110	COG1538	Outer membrane efflux protein
OC371_13115	COG1137	ATPase activity
OC371_13120	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
OC371_13130	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OC371_13135	COG0517	IMP dehydrogenase activity
OC371_13135	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OC371_13170	COG2814	Major facilitator Superfamily
OC371_13205	COG1278	Cold shock
OC371_13210	COG1280	lysine exporter protein (LysE YggA)
OC371_13240	COG1570	exodeoxyribonuclease VII activity
OC371_13295	COG0583	DNA-binding transcription factor activity
OC371_13305	COG4638	Rieske (2fe-2S)
OC371_13310	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
OC371_13315	COG0543	2 iron, 2 sulfur cluster binding
OC371_13315	COG0633	Ferredoxin
OC371_13320	COG1028	Short-chain dehydrogenase reductase Sdr
OC371_13325	COG3135	benzoate transporter
OC371_13330	COG2814	Major facilitator Superfamily
OC371_13345	COG1643	Atp-dependent helicase
OC371_13350	COG0450	alkyl hydroperoxide reductase
OC371_13360	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OC371_13370	COG3634	alkyl hydroperoxide reductase activity
OC371_13390	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OC371_13395	COG0625	glutathione transferase activity
OC371_13405	COG2885	chlorophyll binding
OC371_13440	COG0542	response to heat
OC371_13455	COG1765	OsmC-like protein
OC371_13470	COG0667	Aldo Keto reductase
OC371_13485	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OC371_13495	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OC371_13505	COG0527	aspartate kinase activity
OC371_13515	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OC371_13525	COG3038	cytochrome b561
OC371_13530	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OC371_13535	COG2252	PERMEase
OC371_13545	COG2072	flavoprotein involved in K transport
OC371_13560	COG1741	Belongs to the pirin family
OC371_13565	COG1309	transcriptional regulator
OC371_13595	COG0300	oxidoreductase activity
OC371_13670	COG0488	(ABC) transporter
OC371_13675	COG3173	Aminoglycoside phosphotransferase
OC371_13750	COG4269	membrane
OC371_13765	COG0446	pyridine nucleotide-disulphide oxidoreductase
OC371_13765	COG1902	pentaerythritol trinitrate reductase activity
OC371_13775	COG5001	Diguanylate cyclase
OC371_13775	COG4251	negative regulation of phosphorylation
OC371_13775	COG2203	Gaf domain
OC371_13775	COG3706	GGDEF domain
OC371_13785	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OC371_13805	COG4172	Belongs to the ABC transporter superfamily
OC371_13810	COG4239	(ABC) transporter, permease
OC371_13815	COG4174	ABC transporter (Permease)
OC371_13825	COG0741	lytic transglycosylase activity
OC371_13825	COG1388	LysM domain
OC371_13825	COG1388	LysM domain
OC371_13825	COG0741	lytic transglycosylase activity
OC371_13830	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OC371_13870	COG0583	DNA-binding transcription factor activity
OC371_13875	COG1279	arginine transmembrane transporter activity
OC371_13895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OC371_13900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OC371_13905	COG0006	proline dipeptidase activity
OC371_13945	COG2194	sulfuric ester hydrolase activity
OC371_13990	COG0739	heme binding
OC371_14105	COG5410	chromosome segregation
OC371_14295	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OC371_14320	COG3384	dioxygenase
OC371_14330	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OC371_14335	COG2878	Part of a membrane complex involved in electron transport
OC371_14340	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OC371_14365	COG0768	penicillin binding
OC371_14370	COG0742	ribosomal rna small subunit methyltransferase
OC371_14385	COG0830	nickel cation binding
OC371_14395	COG0804	urea catabolic process
OC371_14435	COG1253	flavin adenine dinucleotide binding
OC371_14440	COG2851	Citrate transporter
OC371_14490	COG1773	rubredoxin
OC371_14495	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OC371_14505	COG0583	DNA-binding transcription factor activity
OC371_14535	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
OC371_14540	COG4181	ATPase activity
OC371_14585	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OC371_14605	COG0306	phosphate transporter
OC371_14615	COG3958	Transketolase
OC371_14620	COG3959	Transketolase, thiamine diphosphate binding domain
OC371_14625	COG2271	Major facilitator Superfamily
OC371_14630	COG1028	Short-chain dehydrogenase reductase Sdr
OC371_14635	COG0583	DNA-binding transcription factor activity
OC371_14650	COG2223	nitrite transmembrane transporter activity
OC371_14655	COG2207	Transcriptional regulator
OC371_14660	COG2066	Belongs to the glutaminase family
OC371_14665	COG0242	peptide deformylase activity
OC371_14670	COG0477	Major facilitator Superfamily
OC371_14680	COG0028	Belongs to the TPP enzyme family
OC371_14695	COG1028	Short-chain dehydrogenase reductase Sdr
OC371_14700	COG2267	carboxylic ester hydrolase activity
OC371_14710	COG2271	Major facilitator Superfamily
OC371_14715	COG0446	pyridine nucleotide-disulphide oxidoreductase
OC371_14725	COG1028	Short-chain dehydrogenase reductase Sdr
OC371_14745	COG1414	Transcriptional regulator
OC371_14760	COG1024	Enoyl-CoA hydratase
OC371_14770	COG1215	transferase activity, transferring glycosyl groups
OC371_14775	COG0726	polysaccharide deacetylase
OC371_14775	COG1649	PFAM Uncharacterised BCR, COG1649
OC371_14785	COG4681	YaeQ
OC371_14795	COG0523	cobalamin synthesis protein
OC371_14805	COG1607	acyl-coa hydrolase
OC371_14815	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OC371_14820	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OC371_14825	COG1309	transcriptional regulator
OC371_14850	COG2040	homocysteine
OC371_14855	COG0531	amino acid
OC371_14910	COG1595	DNA-templated transcription, initiation
OC371_14920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OC371_14925	COG0477	Major facilitator Superfamily
OC371_14965	COG0405	Gamma-glutamyltransferase
OC371_14970	COG2814	Major facilitator Superfamily
OC371_14980	COG2050	protein possibly involved in aromatic compounds catabolism
OC371_14995	COG1090	epimerase
OC371_15015	COG0420	3'-5' exonuclease activity
OC371_15040	COG0735	belongs to the Fur family
OC371_15045	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OC371_15065	COG0121	glutamine amidotransferase
OC371_15080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OC371_15090	COG0210	DNA helicase
OC371_15095	COG2885	chlorophyll binding
OC371_15100	COG0204	Acyl-transferase
OC371_15115	COG2894	cell division
OC371_15140	COG4372	Transposase
OC371_15150	COG1280	lysine exporter protein (LysE YggA)
OC371_15155	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OC371_15155	COG1674	ftsk spoiiie
OC371_15160	COG0492	ferredoxin-NADP+ reductase activity
OC371_15165	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OC371_15175	COG0456	acetyltransferase
OC371_15220	COG1981	membrane
OC371_15235	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OC371_15235	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OC371_15255	COG1012	belongs to the aldehyde dehydrogenase family
OC371_15265	COG0657	acetylesterase activity
OC371_15275	COG0473	3-isopropylmalate dehydrogenase activity
OC371_15280	COG0583	DNA-binding transcription factor activity
OC371_15300	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OC371_15325	COG0564	pseudouridine synthase activity
OC371_15335	COG0358	DNA primase activity
OC371_15350	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
OC371_15380	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OC371_15410	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OC371_15420	COG0351	phosphomethylpyrimidine kinase
OC371_15420	COG0352	thiamine-phosphate diphosphorylase activity
OC371_15420	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OC371_15425	COG1652	LysM domain
OC371_15450	COG1399	metal-binding, possibly nucleic acid-binding protein
OC371_15455	COG3101	peptidyl-lysine hydroxylation
OC371_15460	COG0009	L-threonylcarbamoyladenylate synthase
OC371_15465	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OC371_15470	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OC371_15485	COG4106	trans-aconitate 2-methyltransferase activity
OC371_15500	COG2226	methyltransferase
OC371_15500	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OC371_15500	COG0596	Alpha beta hydrolase
OC371_15505	COG2826	transposase and inactivated derivatives, IS30 family
OC371_15510	COG1877	trehalose-phosphatase activity
OC371_15515	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
OC371_15520	COG2223	nitrite transmembrane transporter activity
OC371_15540	COG1196	nuclear chromosome segregation
OC371_15550	COG0730	response to heat
OC371_15565	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OC371_15575	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OC371_15625	COG0489	protein tyrosine kinase activity
OC371_15635	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OC371_15635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OC371_15665	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OC371_15670	COG2081	HI0933 family
OC371_15680	COG0668	transmembrane transport
OC371_15700	COG0583	DNA-binding transcription factor activity
OC371_15720	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OC371_15725	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OC371_15755	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OC371_15795	COG0745	RESPONSE REGULATOR receiver
OC371_15815	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OC371_15825	COG2205	protein histidine kinase activity
OC371_15895	COG4993	Dehydrogenase
OC371_15920	COG0384	phenazine biosynthesis protein PhzF
OC371_15945	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OC371_15960	COG0583	DNA-binding transcription factor activity
OC371_15990	COG0583	DNA-binding transcription factor activity
OC371_16005	COG0583	DNA-binding transcription factor activity
OC371_16010	COG1053	succinate dehydrogenase
OC371_16020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OC371_16025	COG2814	Major facilitator Superfamily
OC371_16030	COG1960	acyl-CoA dehydrogenase activity
OC371_16035	COG0583	DNA-binding transcription factor activity
OC371_16040	COG1063	alcohol dehydrogenase
OC371_16070	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OC371_16075	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OC371_16080	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OC371_16095	COG3667	copper resistance
OC371_16100	COG2132	Multicopper oxidase
OC371_16110	COG0561	phosphatase activity
OC371_16115	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OC371_16140	COG1214	PFAM Peptidase M22, glycoprotease
OC371_16195	COG4372	Transposase
OC371_16215	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OC371_16225	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OC371_16230	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OC371_16235	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OC371_16295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OC371_16305	COG1846	Transcriptional regulator
OC371_16310	COG1764	response to oxidative stress
OC371_16350	COG0037	tRNA processing
OC371_16360	COG0248	Ppx GppA phosphatase
OC371_16390	COG0072	phenylalanine-tRNA ligase activity
OC371_16435	COG1238	metal cluster binding
OC371_16440	COG0625	glutathione transferase activity
OC371_16455	COG0318	PFAM AMP-dependent synthetase and ligase
OC371_16460	COG3028	Belongs to the UPF0307 family
OC371_16465	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OC371_16485	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OC371_16490	COG0617	tRNA 3'-terminal CCA addition
OC371_16495	COG1555	photosystem II stabilization
OC371_16500	COG3956	TIGRFAM MazG family protein
OC371_16510	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OC371_16530	COG0784	Response regulator, receiver
OC371_16530	COG5002	protein histidine kinase activity
OC371_16530	COG2205	protein histidine kinase activity
OC371_16535	COG1024	Enoyl-CoA hydratase
OC371_16540	COG2084	Dehydrogenase
OC371_16545	COG3622	Belongs to the hyi family
OC371_16595	COG2814	Major facilitator Superfamily
OC371_16600	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OC371_16610	COG0583	DNA-binding transcription factor activity
OC371_16620	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OC371_16635	COG0084	hydrolase, TatD family'
OC371_16650	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OC371_16680	COG0440	acetolactate synthase activity
OC371_16685	COG0028	Belongs to the TPP enzyme family
OC371_16710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OC371_16715	COG1136	(ABC) transporter
OC371_16715	COG0577	efflux transmembrane transporter activity
OC371_16720	COG1538	Outer membrane efflux protein
OC371_16735	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OC371_16740	COG1162	GTPase activity
OC371_16750	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OC371_16770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OC371_16775	COG1028	Short-chain dehydrogenase reductase Sdr
OC371_16815	COG2986	histidine ammonia-lyase
OC371_16830	COG0318	PFAM AMP-dependent synthetase and ligase
OC371_16840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OC371_16885	COG1426	Protein conserved in bacteria
OC371_16920	COG0793	Belongs to the peptidase S41A family
OC371_16935	COG2267	carboxylic ester hydrolase activity
OC371_16945	COG1012	belongs to the aldehyde dehydrogenase family
OC371_16950	COG3265	gluconokinase activity
OC371_16960	COG0800	Aldolase
OC371_16970	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OC371_16975	COG0857	belongs to the CobB CobQ family
OC371_16975	COG0280	phosphate acetyltransferase
OC371_16980	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
OC371_16980	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
OC371_17000	COG0740	serine-type endopeptidase activity
OC371_17010	COG4774	siderophore transport
OC371_17020	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OC371_17030	COG2813	Specifically methylates the guanine in position
OC371_17030	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OC371_17130	COG0788	formyltetrahydrofolate deformylase activity
OC371_17155	COG4651	solute:proton antiporter activity
OC371_17155	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OC371_17175	COG0724	RNA recognition motif
OC371_17180	COG0210	DNA helicase
OC371_17205	COG1733	regulation of RNA biosynthetic process
OC371_17215	COG2900	Belongs to the SlyX family
OC371_17220	COG0488	(ABC) transporter
OC371_17225	COG1280	lysine exporter protein (LysE YggA)
OC371_17230	COG1560	Kdo2-lipid A biosynthetic process
OC371_17240	COG1301	dicarboxylic acid transport
OC371_17295	COG0473	3-isopropylmalate dehydrogenase activity
OC371_17360	COG0583	DNA-binding transcription factor activity
OC371_17370	COG0625	glutathione transferase activity
OC371_17375	COG2378	regulation of single-species biofilm formation
OC371_17380	COG0546	phosphoglycolate phosphatase activity
OC371_17390	COG1530	ribonuclease E activity
OC371_17395	COG0318	PFAM AMP-dependent synthetase and ligase
OC371_17410	COG0583	DNA-binding transcription factor activity
OC371_17415	COG4221	oxidoreductase activity
OC371_17420	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OC371_17430	COG0534	Mate efflux family protein
OC371_17445	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OC371_17485	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
OC371_17490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OC371_17505	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OC371_17515	COG0644	oxidoreductase
OC371_17515	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
OC371_17520	COG0425	Belongs to the sulfur carrier protein TusA family
OC371_17525	COG4535	Mg2 and Co2 transporter CorC
OC371_17535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OC371_17555	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OC371_17560	COG0475	glutathione-regulated potassium exporter activity
OC371_17560	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OC371_17565	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OC371_17575	COG0484	heat shock protein binding
OC371_17580	COG0789	Transcriptional regulator
OC371_17585	COG0598	Magnesium transport protein CorA
OC371_17600	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OC371_17605	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OC371_17610	COG1074	ATP-dependent DNA helicase activity
OC371_17615	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
OC371_17635	COG2226	methyltransferase
OC371_17655	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OC371_17670	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OC371_17670	COG2111	Na H antiporter
OC371_17675	COG1006	Multisubunit Na H antiporter MnhC subunit
OC371_17680	COG0651	ATP synthesis coupled electron transport
OC371_17685	COG1863	multisubunit Na H antiporter MnhE subunit
OC371_17690	COG2212	antiporter activity
OC371_17695	COG1320	monovalent cation:proton antiporter activity
OC371_17710	COG0195	Participates in both transcription termination and antitermination
OC371_17760	COG0237	dephospho-CoA kinase activity
OC371_17770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OC371_17785	COG0497	DNA recombination
OC371_17795	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OC371_17825	COG2169	Transcriptional regulator
OC371_17825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OC371_17830	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OC371_17895	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OC371_17910	COG0326	Molecular chaperone. Has ATPase activity
OC371_17925	COG2056	Na+-H+ antiporter family
OC371_17930	COG0596	Alpha beta hydrolase
OC371_18030	COG0546	phosphoglycolate phosphatase activity
OC371_18035	COG1716	ATPase activity
OC371_18085	COG0181	hydroxymethylbilane synthase activity
OC371_18095	COG3275	phosphorelay sensor kinase activity
OC371_18115	COG1538	Outer membrane efflux protein
OC371_18120	COG0697	spore germination
OC371_18145	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OC371_18150	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OC371_18155	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OC371_18160	COG0772	Belongs to the SEDS family
OC371_18185	COG4974	Belongs to the 'phage' integrase family
OC371_18190	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OC371_18200	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OC371_18210	COG2197	response regulator
OC371_18225	COG0793	Belongs to the peptidase S41A family
OC371_18230	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OC371_18235	COG0795	lipopolysaccharide-transporting ATPase activity
OC371_18275	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OC371_18275	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OC371_18285	COG0004	ammonium transporteR
OC371_18290	COG0347	Belongs to the P(II) protein family
OC371_18300	COG0606	chelatase, subunit chli
OC371_18315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OC371_18330	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OC371_18345	COG0318	PFAM AMP-dependent synthetase and ligase
OC371_18355	COG0477	Major facilitator Superfamily
OC371_18360	COG2860	membrane
OC371_18365	COG3012	SEC-C Motif Domain Protein
OC371_18370	COG1253	flavin adenine dinucleotide binding
OC371_18380	COG2814	Major facilitator Superfamily
OC371_18390	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OC371_18430	COG0655	NAD(P)H dehydrogenase (quinone) activity
OC371_18440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OC371_18510	COG0758	DNA mediated transformation
OC371_18520	COG0697	spore germination
OC371_18525	COG1309	transcriptional regulator
OC371_18540	COG0386	Belongs to the glutathione peroxidase family
OC371_18610	COG1121	(ABC) transporter
OC371_18615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OC371_18620	COG1280	lysine exporter protein (LysE YggA)
OC371_18625	COG2837	iron assimilation
OC371_18630	COG0281	malic enzyme
OC371_18685	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OC371_18685	COG0519	Catalyzes the synthesis of GMP from XMP
OC371_18690	COG4399	Belongs to the UPF0754 family
OC371_18695	COG2259	Doxx family
OC371_18700	COG0586	Pfam SNARE associated Golgi protein
OC371_18715	COG1192	Involved in chromosome partitioning
OC371_18725	COG0271	Belongs to the BolA IbaG family
OC371_18765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OC371_18765	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OC371_18765	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
OC371_18765	COG3321	synthase
OC371_18770	COG1960	acyl-CoA dehydrogenase activity
OC371_18780	COG2197	response regulator
OC371_18790	COG3916	Acyl-homoserine-lactone synthase
OC371_18795	COG0477	Major facilitator Superfamily
OC371_18800	COG1024	Enoyl-CoA hydratase
OC371_18805	COG1024	Enoyl-CoA hydratase
OC371_18810	COG1960	acyl-CoA dehydrogenase activity
OC371_18815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OC371_18835	COG1113	amino acid transport
OC371_18840	COG1113	amino acid transport
OC371_18845	COG0251	oxidation-reduction process
OC371_18885	COG0564	pseudouridine synthase activity
OC371_18930	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OC371_18945	COG1802	Transcriptional regulator
OC371_18955	COG1448	Aminotransferase
OC371_18960	COG0277	FAD linked oxidase domain protein
OC371_18970	COG2186	Transcriptional regulator
OC371_18980	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OC371_18990	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OC371_19005	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OC371_19010	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OC371_19035	COG0438	transferase activity, transferring glycosyl groups
OC371_19065	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OC371_19095	COG0728	peptidoglycan biosynthetic process
OC371_19100	COG3023	N-Acetylmuramoyl-L-alanine amidase
OC371_19160	COG0546	phosphoglycolate phosphatase activity
OC371_19165	COG1028	Short-chain dehydrogenase reductase Sdr
OC371_19185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OC371_19190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OC371_19195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OC371_19200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OC371_19205	COG1116	anion transmembrane transporter activity
OC371_19210	COG1309	transcriptional regulator
OC371_19215	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OC371_19225	COG0196	riboflavin kinase activity
OC371_19230	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OC371_19240	COG1047	Peptidyl-prolyl cis-trans
OC371_19280	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OC371_19285	COG0657	acetylesterase activity
OC371_19305	COG0583	DNA-binding transcription factor activity
OC371_19335	COG2951	lytic endotransglycosylase activity
OC371_19340	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OC371_19355	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OC371_19365	COG0671	phosphoesterase, PA-phosphatase related
OC371_19370	COG0861	Integral membrane protein TerC family
OC371_19380	COG0754	glutathionylspermidine amidase activity
OC371_19390	COG0402	S-adenosylhomocysteine deaminase activity
OC371_19405	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OC371_19410	COG1230	cation diffusion facilitator family transporter
OC371_19425	COG0706	membrane insertase activity
OC371_19450	COG1475	DNA binding
OC371_19465	COG3853	Toxic anion resistance protein (TelA)
OC371_19550	COG0484	heat shock protein binding
OC371_19635	COG0741	lytic transglycosylase activity
OC371_19670	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OC371_19750	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OC371_19820	COG1525	nuclease
OC371_19915	COG2826	transposase and inactivated derivatives, IS30 family