locus-tag	class	description
L5465_00005	COG2826	transposase and inactivated derivatives, IS30 family
L5465_00015	COG2826	transposase and inactivated derivatives, IS30 family
L5465_00025	COG3853	Toxic anion resistance protein (TelA)
L5465_00040	COG1475	DNA binding
L5465_00100	COG1525	nuclease
L5465_00175	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L5465_00255	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L5465_00290	COG0741	lytic transglycosylase activity
L5465_00320	COG2826	transposase and inactivated derivatives, IS30 family
L5465_00330	COG2826	transposase and inactivated derivatives, IS30 family
L5465_00390	COG0484	heat shock protein binding
L5465_00475	COG0243	molybdopterin cofactor binding
L5465_00525	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L5465_00535	COG0133	tryptophan synthase activity
L5465_00550	COG3706	GGDEF domain
L5465_00565	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L5465_00570	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L5465_00575	COG0022	dehydrogenase e1 component
L5465_00580	COG0508	dehydrogenase complex catalyzes the overall conversion of
L5465_00585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L5465_00595	COG1063	alcohol dehydrogenase
L5465_00600	COG3781	membrane
L5465_00610	COG3453	Protein conserved in bacteria
L5465_00610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L5465_00625	COG0730	response to heat
L5465_00640	COG3708	Transcriptional regulator
L5465_00640	COG2207	Transcriptional regulator
L5465_00645	COG1733	regulation of RNA biosynthetic process
L5465_00650	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
L5465_00660	COG2188	Transcriptional regulator
L5465_00675	COG4521	taurine ABC transporter
L5465_00680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L5465_00700	COG0477	Major facilitator Superfamily
L5465_00710	COG1027	Aspartate ammonia-lyase
L5465_00725	COG0583	DNA-binding transcription factor activity
L5465_00730	COG0583	DNA-binding transcription factor activity
L5465_00735	COG0183	Belongs to the thiolase family
L5465_00740	COG2031	fatty acid transporter
L5465_00755	COG0583	DNA-binding transcription factor activity
L5465_00775	COG1309	transcriptional regulator
L5465_00785	COG2610	gluconate transmembrane transporter activity
L5465_00790	COG1028	Short-chain dehydrogenase reductase Sdr
L5465_00795	COG2207	Transcriptional regulator
L5465_00810	COG1028	Short-chain dehydrogenase reductase Sdr
L5465_00820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L5465_00835	COG0543	2 iron, 2 sulfur cluster binding
L5465_00835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L5465_00840	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L5465_00845	COG4638	Rieske (2fe-2S)
L5465_00855	COG0725	ABC transporter, periplasmic molybdate-binding protein
L5465_00860	COG4149	molybdate abc transporter
L5465_00865	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
L5465_00870	COG1028	Short-chain dehydrogenase reductase Sdr
L5465_00875	COG1535	isochorismatase
L5465_00875	COG3433	isochorismatase activity
L5465_00935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L5465_00950	COG0753	catalase activity
L5465_00960	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
L5465_00990	COG3539	Fimbrial protein
L5465_01010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L5465_01015	COG0747	negative chemotaxis
L5465_01020	COG0601	transmembrane transport
L5465_01025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L5465_01045	COG1132	(ABC) transporter
L5465_01050	COG1132	(ABC) transporter
L5465_01070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L5465_01085	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
L5465_01100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L5465_01105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L5465_01110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L5465_01115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L5465_01145	COG4771	TonB-dependent receptor
L5465_01150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L5465_01160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L5465_01165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L5465_01170	COG0745	RESPONSE REGULATOR receiver
L5465_01175	COG2205	protein histidine kinase activity
L5465_01185	COG2207	Transcriptional regulator
L5465_01200	COG1028	Short-chain dehydrogenase reductase Sdr
L5465_01245	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
L5465_01295	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L5465_01315	COG1120	ATPase activity
L5465_01320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L5465_01330	COG1064	alcohol dehydrogenase
L5465_01345	COG2207	Transcriptional regulator
L5465_01350	COG2084	Dehydrogenase
L5465_01360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L5465_01365	COG0583	DNA-binding transcription factor activity
L5465_01375	COG0129	dihydroxy-acid dehydratase activity
L5465_01380	COG1012	belongs to the aldehyde dehydrogenase family
L5465_01395	COG1566	PFAM secretion protein HlyD family protein
L5465_01405	COG2271	Major facilitator Superfamily
L5465_01420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L5465_01445	COG0583	DNA-binding transcription factor activity
L5465_01460	COG2188	Transcriptional regulator
L5465_01500	COG4993	Dehydrogenase
L5465_01505	COG1733	regulation of RNA biosynthetic process
L5465_01520	COG2259	Doxx family
L5465_01525	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
L5465_01570	COG1309	transcriptional regulator
L5465_01600	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L5465_01610	COG0446	pyridine nucleotide-disulphide oxidoreductase
L5465_01610	COG1902	pentaerythritol trinitrate reductase activity
L5465_01615	COG1846	Transcriptional regulator
L5465_01635	COG0753	catalase activity
L5465_01650	COG1012	belongs to the aldehyde dehydrogenase family
L5465_01675	COG3829	transcription factor binding
L5465_01680	COG1028	Short-chain dehydrogenase reductase Sdr
L5465_01685	COG1960	acyl-CoA dehydrogenase activity
L5465_01700	COG3231	kanamycin kinase activity
L5465_01705	COG1012	belongs to the aldehyde dehydrogenase family
L5465_01725	COG2186	Transcriptional regulator
L5465_01735	COG0583	DNA-binding transcription factor activity
L5465_01740	COG4948	Mandelate Racemase Muconate Lactonizing
L5465_01745	COG4829	muconolactone delta-isomerase
L5465_01755	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L5465_01760	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L5465_01765	COG0183	Belongs to the thiolase family
L5465_01770	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L5465_01785	COG3733	amine oxidase
L5465_01795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L5465_01805	COG1028	Short-chain dehydrogenase reductase Sdr
L5465_01815	COG4638	Rieske (2fe-2S)
L5465_01845	COG0154	amidase activity
L5465_01855	COG2814	Major facilitator Superfamily
L5465_01880	COG1960	acyl-CoA dehydrogenase activity
L5465_01885	COG0583	DNA-binding transcription factor activity
L5465_01890	COG1414	Transcriptional regulator
L5465_01905	COG2391	methyltransferase activity
L5465_01915	COG4993	Dehydrogenase
L5465_01920	COG3659	wide pore channel activity
L5465_01925	COG3420	alginic acid biosynthetic process
L5465_01930	COG0710	3-dehydroquinate dehydratase activity
L5465_01935	COG3485	protocatechuate 3,4-dioxygenase
L5465_01940	COG3485	protocatechuate 3,4-dioxygenase
L5465_01945	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L5465_01950	COG2271	Major facilitator Superfamily
L5465_01955	COG0596	Alpha beta hydrolase
L5465_01960	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L5465_01965	COG0183	Belongs to the thiolase family
L5465_01970	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L5465_01975	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L5465_01985	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
L5465_01990	COG2323	membrane
L5465_02035	COG0446	pyridine nucleotide-disulphide oxidoreductase
L5465_02035	COG1902	pentaerythritol trinitrate reductase activity
L5465_02060	COG0542	response to heat
L5465_02065	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
L5465_02095	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L5465_02100	COG0569	domain protein
L5465_02105	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L5465_02120	COG4774	siderophore transport
L5465_02125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L5465_02135	COG1585	Membrane protein implicated in regulation of membrane protease activity
L5465_02150	COG1294	oxidase, subunit
L5465_02155	COG4890	Cyd operon protein YbgT
L5465_02165	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
L5465_02175	COG0552	protein localization to endoplasmic reticulum
L5465_02200	COG0516	GMP reductase activity
L5465_02200	COG0517	IMP dehydrogenase activity
L5465_02205	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L5465_02210	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
L5465_02220	COG0583	DNA-binding transcription factor activity
L5465_02225	COG0024	Methionine aminopeptidase
L5465_02255	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
L5465_02255	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L5465_02260	COG1105	Belongs to the carbohydrate kinase PfkB family
L5465_02265	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L5465_02265	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
L5465_02265	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L5465_02280	COG3300	MHYT domain
L5465_02280	COG5001	Diguanylate cyclase
L5465_02300	COG0659	secondary active sulfate transmembrane transporter activity
L5465_02320	COG1113	amino acid transport
L5465_02355	COG1011	Hydrolase
L5465_02360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L5465_02370	COG2137	regulation of response to DNA damage stimulus
L5465_02385	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L5465_02420	COG0575	Belongs to the CDS family
L5465_02425	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L5465_02450	COG3852	Histidine kinase
L5465_02455	COG2204	response regulator
L5465_02510	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L5465_02515	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
L5465_02535	COG0697	spore germination
L5465_02540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L5465_02550	COG0303	'Molybdopterin
L5465_02555	COG0521	Mo-molybdopterin cofactor biosynthetic process
L5465_02555	COG0315	cyclic pyranopterin monophosphate synthase activity
L5465_02570	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L5465_02580	COG0243	molybdopterin cofactor binding
L5465_02600	COG0243	molybdopterin cofactor binding
L5465_02605	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L5465_02610	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L5465_02610	COG2146	nitrite reductase [NAD(P)H] activity
L5465_02620	COG0745	RESPONSE REGULATOR receiver
L5465_02625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L5465_02625	COG1116	anion transmembrane transporter activity
L5465_02645	COG0511	ligase activity, forming carbon-carbon bonds
L5465_02660	COG2814	Major facilitator Superfamily
L5465_02735	COG2314	TM2 domain
L5465_02795	COG3566	protein conserved in bacteria
L5465_02815	COG3567	Phage-associated protein, HI1409 family
L5465_02820	COG5410	chromosome segregation
L5465_02905	COG4197	protein conserved in bacteria, prophage-related
L5465_02910	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L5465_02985	COG0069	glutamate synthase activity
L5465_03005	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L5465_03015	COG1454	alcohol dehydrogenase
L5465_03020	COG0824	Thioesterase
L5465_03030	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L5465_03055	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L5465_03060	COG2030	dehydratase
L5465_03070	COG0183	Belongs to the thiolase family
L5465_03080	COG0583	DNA-binding transcription factor activity
L5465_03085	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
L5465_03095	COG1522	sequence-specific DNA binding
L5465_03100	COG3135	benzoate transporter
L5465_03110	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L5465_03135	COG0589	response to stress
L5465_03140	COG0488	(ABC) transporter
L5465_03160	COG4773	Receptor
L5465_03190	COG0668	transmembrane transport
L5465_03230	COG0583	DNA-binding transcription factor activity
L5465_03235	COG2814	Major facilitator Superfamily
L5465_03240	COG2814	Major facilitator Superfamily
L5465_03245	COG0446	pyridine nucleotide-disulphide oxidoreductase
L5465_03250	COG3384	dioxygenase
L5465_03255	COG1028	Short-chain dehydrogenase reductase Sdr
L5465_03265	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L5465_03270	COG4638	Rieske (2fe-2S)
L5465_03275	COG0583	DNA-binding transcription factor activity
L5465_03295	COG4569	acetaldehyde dehydrogenase (acetylating) activity
L5465_03300	COG3971	2-oxopent-4-enoate hydratase activity
L5465_03310	COG2271	Major facilitator Superfamily
L5465_03315	COG1234	tRNA 3'-trailer cleavage
L5465_03345	COG1538	Outer membrane efflux protein
L5465_03355	COG2885	chlorophyll binding
L5465_03355	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
L5465_03400	COG1605	Chorismate mutase
L5465_03420	COG0308	aminopeptidase N
L5465_03440	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
L5465_03450	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L5465_03455	COG1454	alcohol dehydrogenase
L5465_03475	COG0531	amino acid
L5465_03480	COG4303	Ethanolamine ammonia lyase large subunit
L5465_03485	COG4302	ethanolamine ammonia-lyase activity
L5465_03490	COG0519	Catalyzes the synthesis of GMP from XMP
L5465_03490	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L5465_03495	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L5465_03520	COG0697	spore germination
L5465_03525	COG1923	regulation of RNA biosynthetic process
L5465_03535	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
L5465_03540	COG0802	atpase or kinase
L5465_03560	COG1187	pseudouridine synthase activity
L5465_03575	COG0583	DNA-binding transcription factor activity
L5465_03590	COG2814	Major facilitator Superfamily
L5465_03595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L5465_03620	COG0729	surface antigen
L5465_03640	COG0174	glutamine synthetase
L5465_03645	COG0745	RESPONSE REGULATOR receiver
L5465_03650	COG2205	protein histidine kinase activity
L5465_03660	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
L5465_03665	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
L5465_03690	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L5465_03695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L5465_03700	COG1960	acyl-CoA dehydrogenase activity
L5465_03730	COG0583	DNA-binding transcription factor activity
L5465_03745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L5465_03755	COG3658	cytochrome
L5465_03760	COG1215	transferase activity, transferring glycosyl groups
L5465_03765	COG0726	polysaccharide deacetylase
L5465_03765	COG1649	PFAM Uncharacterised BCR, COG1649
L5465_03790	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L5465_03795	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L5465_03805	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
L5465_03830	COG0305	Participates in initiation and elongation during chromosome replication
L5465_03835	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L5465_03845	COG1305	Transglutaminase-like
L5465_03855	COG2308	Evidence 4 Homologs of previously reported genes of
L5465_03885	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
L5465_03890	COG0138	bifunctional purine biosynthesis protein purh
L5465_03895	COG0151	Belongs to the GarS family
L5465_03900	COG1464	Belongs to the NlpA lipoprotein family
L5465_03905	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L5465_03910	COG2011	ABC-type metal ion transport system permease component
L5465_03915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L5465_03925	COG1301	dicarboxylic acid transport
L5465_03950	COG2814	Major facilitator Superfamily
L5465_04040	COG4397	Mu-like prophage major head subunit gpT
L5465_04055	COG5005	Phage virion morphogenesis
L5465_04060	COG2369	cell adhesion
L5465_04065	COG4383	Mu-like prophage protein gp29
L5465_04080	COG4373	Mu-like prophage FluMu protein gp28
L5465_04115	COG2932	Transcriptional regulator
L5465_04180	COG0776	regulation of translation
L5465_04225	COG1309	transcriptional regulator
L5465_04245	COG1794	racemase activity, acting on amino acids and derivatives
L5465_04250	COG0492	ferredoxin-NADP+ reductase activity
L5465_04250	COG3118	belongs to the thioredoxin family
L5465_04265	COG3008	intermembrane lipid transfer
L5465_04265	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
L5465_04270	COG2995	paraquat-inducible protein a
L5465_04300	COG1051	belongs to the nudix hydrolase family
L5465_04305	COG0477	Major facilitator Superfamily
L5465_04355	COG2186	Transcriptional regulator
L5465_04365	COG0786	glutamate:sodium symporter activity
L5465_04370	COG3243	poly(R)-hydroxyalkanoic acid synthase
L5465_04395	COG3111	PFAM Bacterial OB fold (BOF) protein
L5465_04405	COG2226	methyltransferase
L5465_04480	COG3210	domain, Protein
L5465_04480	COG3210	domain, Protein
L5465_04485	COG2831	hemolysin activation secretion protein
L5465_04510	COG0515	serine threonine protein kinase
L5465_04510	COG2815	serine threonine protein kinase
L5465_04540	COG1610	YqeY-like protein
L5465_04545	COG4783	chaperone-mediated protein folding
L5465_04570	COG1286	toxin biosynthetic process
L5465_04600	COG0778	Nitroreductase
L5465_04610	COG0513	Belongs to the DEAD box helicase family
L5465_04635	COG2363	Small membrane protein
L5465_04665	COG4650	regulator
L5465_04670	COG1234	tRNA 3'-trailer cleavage
L5465_04675	COG1690	Belongs to the RtcB family
L5465_04695	COG2195	Cleaves the N-terminal amino acid of tripeptides
L5465_04705	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
L5465_04715	COG2819	hydrolase of the alpha beta superfamily
L5465_04720	COG1960	acyl-CoA dehydrogenase activity
L5465_04725	COG1301	dicarboxylic acid transport
L5465_04730	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L5465_04735	COG3139	Protein of unknown function (DUF1315)
L5465_04740	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
L5465_04745	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L5465_04755	COG0494	nUDIX hydrolase
L5465_04765	COG0642	Histidine kinase
L5465_04780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L5465_04790	COG1720	tRNA m6t6A37 methyltransferase activity
L5465_04805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L5465_04810	COG0826	peptidase U32
L5465_04815	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L5465_04825	COG4598	ABC transporter
L5465_04830	COG4160	amino acid transport
L5465_04835	COG4215	(ABC) transporter
L5465_05030	COG0515	serine threonine protein kinase
L5465_05030	COG2815	serine threonine protein kinase
L5465_05090	COG5410	chromosome segregation
L5465_05255	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L5465_05270	COG3384	dioxygenase
L5465_05280	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L5465_05285	COG2878	Part of a membrane complex involved in electron transport
L5465_05290	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L5465_05315	COG0768	penicillin binding
L5465_05320	COG0742	ribosomal rna small subunit methyltransferase
L5465_05335	COG0830	nickel cation binding
L5465_05345	COG0804	urea catabolic process
L5465_05385	COG1253	flavin adenine dinucleotide binding
L5465_05390	COG2851	Citrate transporter
L5465_05440	COG1773	rubredoxin
L5465_05445	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L5465_05455	COG0583	DNA-binding transcription factor activity
L5465_05485	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
L5465_05490	COG4181	ATPase activity
L5465_05535	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L5465_05555	COG0306	phosphate transporter
L5465_05565	COG3958	Transketolase
L5465_05570	COG3959	Transketolase, thiamine diphosphate binding domain
L5465_05575	COG2271	Major facilitator Superfamily
L5465_05580	COG1028	Short-chain dehydrogenase reductase Sdr
L5465_05585	COG0583	DNA-binding transcription factor activity
L5465_05600	COG2223	nitrite transmembrane transporter activity
L5465_05605	COG2207	Transcriptional regulator
L5465_05610	COG2066	Belongs to the glutaminase family
L5465_05615	COG0242	peptide deformylase activity
L5465_05620	COG0477	Major facilitator Superfamily
L5465_05630	COG0028	Belongs to the TPP enzyme family
L5465_05645	COG1028	Short-chain dehydrogenase reductase Sdr
L5465_05650	COG2267	carboxylic ester hydrolase activity
L5465_05660	COG2271	Major facilitator Superfamily
L5465_05675	COG1028	Short-chain dehydrogenase reductase Sdr
L5465_05695	COG1414	Transcriptional regulator
L5465_05710	COG1024	Enoyl-CoA hydratase
L5465_05720	COG1215	transferase activity, transferring glycosyl groups
L5465_05725	COG1649	PFAM Uncharacterised BCR, COG1649
L5465_05725	COG0726	polysaccharide deacetylase
L5465_05735	COG4681	YaeQ
L5465_05745	COG0523	cobalamin synthesis protein
L5465_05755	COG1607	acyl-coa hydrolase
L5465_05765	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L5465_05770	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L5465_05775	COG1309	transcriptional regulator
L5465_05800	COG2040	homocysteine
L5465_05805	COG0531	amino acid
L5465_05860	COG1595	DNA-templated transcription, initiation
L5465_05870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L5465_05875	COG0477	Major facilitator Superfamily
L5465_05885	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
L5465_05950	COG0405	Gamma-glutamyltransferase
L5465_05955	COG2814	Major facilitator Superfamily
L5465_05965	COG2050	protein possibly involved in aromatic compounds catabolism
L5465_06000	COG0420	3'-5' exonuclease activity
L5465_06025	COG0735	belongs to the Fur family
L5465_06030	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L5465_06050	COG0121	glutamine amidotransferase
L5465_06065	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L5465_06075	COG0210	DNA helicase
L5465_06080	COG2885	chlorophyll binding
L5465_06085	COG0204	Acyl-transferase
L5465_06100	COG2894	cell division
L5465_06120	COG1280	lysine exporter protein (LysE YggA)
L5465_06125	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
L5465_06125	COG1674	ftsk spoiiie
L5465_06130	COG0492	ferredoxin-NADP+ reductase activity
L5465_06135	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
L5465_06145	COG0456	acetyltransferase
L5465_06190	COG1981	membrane
L5465_06205	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
L5465_06205	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L5465_06225	COG1012	belongs to the aldehyde dehydrogenase family
L5465_06235	COG0657	acetylesterase activity
L5465_06245	COG0473	3-isopropylmalate dehydrogenase activity
L5465_06250	COG0583	DNA-binding transcription factor activity
L5465_06270	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L5465_06295	COG0564	pseudouridine synthase activity
L5465_06320	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
L5465_06350	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L5465_06380	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L5465_06390	COG0351	phosphomethylpyrimidine kinase
L5465_06390	COG0352	thiamine-phosphate diphosphorylase activity
L5465_06390	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L5465_06395	COG1652	LysM domain
L5465_06420	COG1399	metal-binding, possibly nucleic acid-binding protein
L5465_06425	COG3101	peptidyl-lysine hydroxylation
L5465_06430	COG0009	L-threonylcarbamoyladenylate synthase
L5465_06435	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
L5465_06440	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
L5465_06455	COG4106	trans-aconitate 2-methyltransferase activity
L5465_06470	COG0596	Alpha beta hydrolase
L5465_06470	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L5465_06470	COG2226	methyltransferase
L5465_06475	COG1877	trehalose-phosphatase activity
L5465_06480	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
L5465_06485	COG2223	nitrite transmembrane transporter activity
L5465_06505	COG1196	nuclear chromosome segregation
L5465_06515	COG0730	response to heat
L5465_06530	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L5465_06540	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L5465_06595	COG0489	protein tyrosine kinase activity
L5465_06605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L5465_06605	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L5465_06635	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L5465_06640	COG2081	HI0933 family
L5465_06650	COG0668	transmembrane transport
L5465_06670	COG0583	DNA-binding transcription factor activity
L5465_06690	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L5465_06695	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L5465_06725	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
L5465_06765	COG0745	RESPONSE REGULATOR receiver
L5465_06785	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L5465_06800	COG0384	phenazine biosynthesis protein PhzF
L5465_06820	COG1309	transcriptional regulator
L5465_06825	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L5465_06840	COG0583	DNA-binding transcription factor activity
L5465_06870	COG0583	DNA-binding transcription factor activity
L5465_06885	COG0583	DNA-binding transcription factor activity
L5465_06890	COG1053	succinate dehydrogenase
L5465_06900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L5465_06905	COG2814	Major facilitator Superfamily
L5465_06910	COG1960	acyl-CoA dehydrogenase activity
L5465_06915	COG0583	DNA-binding transcription factor activity
L5465_06920	COG1063	alcohol dehydrogenase
L5465_06950	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
L5465_06955	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
L5465_06960	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L5465_06980	COG0243	molybdopterin cofactor binding
L5465_07005	COG2132	Multicopper oxidase
L5465_07015	COG0561	phosphatase activity
L5465_07020	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L5465_07030	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
L5465_07045	COG1214	PFAM Peptidase M22, glycoprotease
L5465_07095	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
L5465_07105	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
L5465_07110	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
L5465_07115	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L5465_07175	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L5465_07185	COG1846	Transcriptional regulator
L5465_07190	COG1764	response to oxidative stress
L5465_07230	COG0037	tRNA processing
L5465_07240	COG0248	Ppx GppA phosphatase
L5465_07270	COG0072	phenylalanine-tRNA ligase activity
L5465_07315	COG1238	metal cluster binding
L5465_07320	COG0625	glutathione transferase activity
L5465_07335	COG0318	PFAM AMP-dependent synthetase and ligase
L5465_07340	COG3028	Belongs to the UPF0307 family
L5465_07345	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L5465_07365	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L5465_07370	COG0617	tRNA 3'-terminal CCA addition
L5465_07375	COG1555	photosystem II stabilization
L5465_07380	COG3956	TIGRFAM MazG family protein
L5465_07390	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L5465_07410	COG5002	protein histidine kinase activity
L5465_07410	COG2205	protein histidine kinase activity
L5465_07410	COG0784	Response regulator, receiver
L5465_07415	COG1024	Enoyl-CoA hydratase
L5465_07420	COG2084	Dehydrogenase
L5465_07425	COG3622	Belongs to the hyi family
L5465_07455	COG0697	spore germination
L5465_07465	COG2814	Major facilitator Superfamily
L5465_07480	COG0431	NADPH-dependent FMN reductase
L5465_07485	COG0798	PFAM Bile acid sodium symporter
L5465_07495	COG0640	Transcriptional regulator
L5465_07510	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L5465_07545	COG0789	Transcriptional regulator
L5465_07555	COG2132	Multicopper oxidase
L5465_07570	COG2205	protein histidine kinase activity
L5465_07660	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L5465_07670	COG0583	DNA-binding transcription factor activity
L5465_07680	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L5465_07695	COG0084	hydrolase, TatD family'
L5465_07710	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
L5465_07765	COG0440	acetolactate synthase activity
L5465_07770	COG0028	Belongs to the TPP enzyme family
L5465_07795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L5465_07800	COG1136	(ABC) transporter
L5465_07800	COG0577	efflux transmembrane transporter activity
L5465_07805	COG1538	Outer membrane efflux protein
L5465_07820	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
L5465_07825	COG1162	GTPase activity
L5465_07835	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
L5465_07875	COG1426	Protein conserved in bacteria
L5465_07910	COG0793	Belongs to the peptidase S41A family
L5465_07925	COG2267	carboxylic ester hydrolase activity
L5465_07935	COG1012	belongs to the aldehyde dehydrogenase family
L5465_07940	COG3265	gluconokinase activity
L5465_07950	COG0800	Aldolase
L5465_07960	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L5465_07965	COG0280	phosphate acetyltransferase
L5465_07965	COG0857	belongs to the CobB CobQ family
L5465_07970	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
L5465_07970	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
L5465_07990	COG0740	serine-type endopeptidase activity
L5465_08020	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L5465_08030	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L5465_08030	COG2813	Specifically methylates the guanine in position
L5465_08135	COG0788	formyltetrahydrofolate deformylase activity
L5465_08160	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L5465_08160	COG4651	solute:proton antiporter activity
L5465_08180	COG0724	RNA recognition motif
L5465_08185	COG0210	DNA helicase
L5465_08210	COG1733	regulation of RNA biosynthetic process
L5465_08220	COG2900	Belongs to the SlyX family
L5465_08225	COG0488	(ABC) transporter
L5465_08230	COG2826	transposase and inactivated derivatives, IS30 family
L5465_08240	COG1280	lysine exporter protein (LysE YggA)
L5465_08245	COG1560	Kdo2-lipid A biosynthetic process
L5465_08255	COG1301	dicarboxylic acid transport
L5465_08310	COG0473	3-isopropylmalate dehydrogenase activity
L5465_08365	COG0583	DNA-binding transcription factor activity
L5465_08375	COG0625	glutathione transferase activity
L5465_08380	COG2378	regulation of single-species biofilm formation
L5465_08385	COG0546	phosphoglycolate phosphatase activity
L5465_08395	COG1530	ribonuclease E activity
L5465_08400	COG0318	PFAM AMP-dependent synthetase and ligase
L5465_08415	COG0583	DNA-binding transcription factor activity
L5465_08420	COG4221	oxidoreductase activity
L5465_08425	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L5465_08435	COG0534	Mate efflux family protein
L5465_08450	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L5465_08480	COG0493	'glutamate synthase
L5465_08480	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
L5465_08490	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
L5465_08495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L5465_08510	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L5465_08520	COG0644	oxidoreductase
L5465_08520	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
L5465_08530	COG0425	Belongs to the sulfur carrier protein TusA family
L5465_08535	COG4535	Mg2 and Co2 transporter CorC
L5465_08545	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L5465_08565	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L5465_08570	COG0475	glutathione-regulated potassium exporter activity
L5465_08570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L5465_08585	COG0484	heat shock protein binding
L5465_08590	COG0789	Transcriptional regulator
L5465_08595	COG0598	Magnesium transport protein CorA
L5465_08610	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L5465_08615	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L5465_08620	COG1074	ATP-dependent DNA helicase activity
L5465_08625	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
L5465_08645	COG2226	methyltransferase
L5465_08660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L5465_08675	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
L5465_08690	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L5465_08690	COG2111	Na H antiporter
L5465_08695	COG1006	Multisubunit Na H antiporter MnhC subunit
L5465_08700	COG0651	ATP synthesis coupled electron transport
L5465_08705	COG1863	multisubunit Na H antiporter MnhE subunit
L5465_08710	COG2212	antiporter activity
L5465_08715	COG1320	monovalent cation:proton antiporter activity
L5465_08730	COG0195	Participates in both transcription termination and antitermination
L5465_08780	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
L5465_08785	COG0237	dephospho-CoA kinase activity
L5465_08795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L5465_08810	COG0497	DNA recombination
L5465_08820	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
L5465_08850	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L5465_08850	COG2169	Transcriptional regulator
L5465_08855	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L5465_08925	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L5465_08940	COG0326	Molecular chaperone. Has ATPase activity
L5465_08955	COG2056	Na+-H+ antiporter family
L5465_09055	COG0546	phosphoglycolate phosphatase activity
L5465_09060	COG1716	ATPase activity
L5465_09105	COG0181	hydroxymethylbilane synthase activity
L5465_09115	COG3275	phosphorelay sensor kinase activity
L5465_09135	COG1538	Outer membrane efflux protein
L5465_09140	COG0697	spore germination
L5465_09165	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L5465_09170	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L5465_09175	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L5465_09180	COG0772	Belongs to the SEDS family
L5465_09205	COG4974	Belongs to the 'phage' integrase family
L5465_09210	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L5465_09220	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
L5465_09230	COG2197	response regulator
L5465_09245	COG0793	Belongs to the peptidase S41A family
L5465_09250	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
L5465_09255	COG0795	lipopolysaccharide-transporting ATPase activity
L5465_09295	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L5465_09295	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L5465_09305	COG0004	ammonium transporteR
L5465_09310	COG0347	Belongs to the P(II) protein family
L5465_09330	COG0659	secondary active sulfate transmembrane transporter activity
L5465_09335	COG0589	response to stress
L5465_09360	COG1126	abc transporter atp-binding protein
L5465_09365	COG0765	amino acid transport
L5465_09370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L5465_09385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L5465_09405	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
L5465_09420	COG0318	PFAM AMP-dependent synthetase and ligase
L5465_09430	COG0477	Major facilitator Superfamily
L5465_09435	COG2860	membrane
L5465_09440	COG3012	SEC-C Motif Domain Protein
L5465_09445	COG1253	flavin adenine dinucleotide binding
L5465_09455	COG0477	Major facilitator Superfamily
L5465_09465	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L5465_09475	COG0745	RESPONSE REGULATOR receiver
L5465_09480	COG2205	protein histidine kinase activity
L5465_09485	COG4452	Inner membrane protein CreD
L5465_09525	COG0655	NAD(P)H dehydrogenase (quinone) activity
L5465_09535	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L5465_09605	COG0758	DNA mediated transformation
L5465_09615	COG0697	spore germination
L5465_09620	COG1309	transcriptional regulator
L5465_09635	COG0386	Belongs to the glutathione peroxidase family
L5465_09700	COG1121	(ABC) transporter
L5465_09705	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L5465_09710	COG1280	lysine exporter protein (LysE YggA)
L5465_09715	COG2837	iron assimilation
L5465_09720	COG0281	malic enzyme
L5465_09765	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L5465_09765	COG0519	Catalyzes the synthesis of GMP from XMP
L5465_09770	COG4399	Belongs to the UPF0754 family
L5465_09775	COG2259	Doxx family
L5465_09780	COG0586	Pfam SNARE associated Golgi protein
L5465_09795	COG1192	Involved in chromosome partitioning
L5465_09805	COG0271	Belongs to the BolA IbaG family
L5465_09845	COG3321	synthase
L5465_09845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L5465_09845	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L5465_09845	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
L5465_09850	COG1960	acyl-CoA dehydrogenase activity
L5465_09860	COG2197	response regulator
L5465_09870	COG3916	Acyl-homoserine-lactone synthase
L5465_09880	COG2826	transposase and inactivated derivatives, IS30 family
L5465_09900	COG0673	inositol 2-dehydrogenase activity
L5465_09905	COG1324	tolerance protein
L5465_09930	COG2826	transposase and inactivated derivatives, IS30 family
L5465_09940	COG1024	Enoyl-CoA hydratase
L5465_09945	COG1024	Enoyl-CoA hydratase
L5465_09950	COG1960	acyl-CoA dehydrogenase activity
L5465_09955	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L5465_09975	COG1113	amino acid transport
L5465_09980	COG1113	amino acid transport
L5465_09985	COG0251	oxidation-reduction process
L5465_10025	COG0564	pseudouridine synthase activity
L5465_10120	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L5465_10135	COG1802	Transcriptional regulator
L5465_10145	COG1448	Aminotransferase
L5465_10150	COG0277	FAD linked oxidase domain protein
L5465_10160	COG2186	Transcriptional regulator
L5465_10170	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L5465_10180	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L5465_10195	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L5465_10200	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
L5465_10205	COG1216	Glycosyl transferase, family 2
L5465_10230	COG2244	polysaccharide biosynthetic process
L5465_10235	COG1083	cytidylyl-transferase
L5465_10240	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L5465_10250	COG2089	acid synthase
L5465_10255	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
L5465_10260	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
L5465_10270	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L5465_10300	COG0728	peptidoglycan biosynthetic process
L5465_10305	COG3023	N-Acetylmuramoyl-L-alanine amidase
L5465_10360	COG0546	phosphoglycolate phosphatase activity
L5465_10365	COG1028	Short-chain dehydrogenase reductase Sdr
L5465_10385	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L5465_10390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L5465_10395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L5465_10400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L5465_10405	COG1116	anion transmembrane transporter activity
L5465_10410	COG1309	transcriptional regulator
L5465_10415	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L5465_10425	COG0196	riboflavin kinase activity
L5465_10430	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
L5465_10440	COG1047	Peptidyl-prolyl cis-trans
L5465_10480	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L5465_10485	COG0657	acetylesterase activity
L5465_10505	COG0583	DNA-binding transcription factor activity
L5465_10535	COG2951	lytic endotransglycosylase activity
L5465_10540	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L5465_10555	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
L5465_10565	COG0671	phosphoesterase, PA-phosphatase related
L5465_10570	COG0861	Integral membrane protein TerC family
L5465_10580	COG0754	glutathionylspermidine amidase activity
L5465_10590	COG0402	S-adenosylhomocysteine deaminase activity
L5465_10605	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L5465_10610	COG1230	cation diffusion facilitator family transporter
L5465_10625	COG0706	membrane insertase activity
L5465_10650	COG0592	DNA-directed DNA polymerase activity
L5465_10660	COG0187	DNA topoisomerase II activity
L5465_10670	COG0586	Pfam SNARE associated Golgi protein
L5465_10675	COG0488	(ABC) transporter
L5465_10700	COG0596	Alpha beta hydrolase
L5465_10705	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
L5465_10710	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L5465_10750	COG0733	neurotransmitter:sodium symporter activity
L5465_10785	COG0583	DNA-binding transcription factor activity
L5465_10790	COG2233	PERMEase
L5465_10805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L5465_10845	COG0656	L-ascorbic acid biosynthetic process
L5465_10850	COG0583	DNA-binding transcription factor activity
L5465_10865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L5465_10870	COG1064	alcohol dehydrogenase
L5465_10890	COG1194	a g-specific adenine glycosylase
L5465_10910	COG2983	Belongs to the UPF0260 family
L5465_10915	COG2133	pyrroloquinoline quinone binding
L5465_10920	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L5465_10925	COG2116	formate transmembrane transporter activity
L5465_10945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L5465_10950	COG1335	isochorismatase
L5465_10955	COG0385	Bile acid
L5465_10960	COG0534	Mate efflux family protein
L5465_10965	COG1683	Conserved Protein
L5465_10985	COG0625	glutathione transferase activity
L5465_10995	COG1113	amino acid transport
L5465_11005	COG0523	cobalamin synthesis protein
L5465_11015	COG2188	Transcriptional regulator
L5465_11045	COG0010	Belongs to the arginase family
L5465_11055	COG0546	phosphoglycolate phosphatase activity
L5465_11060	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L5465_11075	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
L5465_11080	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
L5465_11085	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L5465_11085	COG4451	ribulose bisphosphate carboxylase, small
L5465_11090	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
L5465_11095	COG1469	GTP cyclohydrolase I activity
L5465_11105	COG0215	cysteine-tRNA ligase activity
L5465_11120	COG0523	cobalamin synthesis protein
L5465_11150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L5465_11180	COG1294	oxidase, subunit
L5465_11185	COG1271	oxidase subunit
L5465_11230	COG0534	Mate efflux family protein
L5465_11245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L5465_11265	COG2963	transposase activity
L5465_11310	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L5465_11320	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L5465_11325	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
L5465_11410	COG0534	Mate efflux family protein
L5465_11415	COG0436	Aminotransferase
L5465_11420	COG2733	membrane
L5465_11435	COG2918	glutathione biosynthetic process
L5465_11450	COG3409	Peptidoglycan-binding domain 1 protein
L5465_11450	COG1388	LysM domain
L5465_11450	COG5632	N-Acetylmuramoyl-L-alanine amidase
L5465_11495	COG3150	esterase
L5465_11505	COG1028	Short-chain dehydrogenase reductase Sdr
L5465_11510	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
L5465_11520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L5465_11530	COG2233	PERMEase
L5465_11535	COG2351	hydroxyisourate hydrolase activity
L5465_11570	COG3706	GGDEF domain
L5465_11585	COG1393	Belongs to the ArsC family
L5465_11590	COG0708	Exodeoxyribonuclease III
L5465_11620	COG0189	ligase activity
L5465_11640	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L5465_11650	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L5465_11665	COG4942	peptidase
L5465_11675	COG0508	dehydrogenase complex catalyzes the overall conversion of
L5465_11685	COG2119	membrane
L5465_11690	COG4774	siderophore transport
L5465_11695	COG0426	domain, Protein
L5465_11695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L5465_11720	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L5465_11745	COG1902	pentaerythritol trinitrate reductase activity
L5465_11750	COG1519	Transferase
L5465_11755	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L5465_11760	COG0668	transmembrane transport
L5465_11770	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L5465_11775	COG1335	isochorismatase
L5465_11780	COG1522	sequence-specific DNA binding
L5465_11805	COG2198	Histidine kinase
L5465_11805	COG2205	protein histidine kinase activity
L5465_11805	COG0784	Response regulator, receiver
L5465_11810	COG3162	membrane
L5465_11815	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L5465_11825	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L5465_11845	COG1309	transcriptional regulator
L5465_11865	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L5465_11865	COG0351	phosphomethylpyrimidine kinase
L5465_11865	COG0352	thiamine-phosphate diphosphorylase activity
L5465_11875	COG2814	Major facilitator Superfamily
L5465_11890	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L5465_11900	COG1113	amino acid transport
L5465_11910	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L5465_11915	COG1012	belongs to the aldehyde dehydrogenase family
L5465_11925	COG1335	isochorismatase
L5465_11955	COG2814	Major facilitator Superfamily
L5465_11960	COG0583	DNA-binding transcription factor activity
L5465_11980	COG0667	Aldo Keto reductase
L5465_12000	COG1733	regulation of RNA biosynthetic process
L5465_12030	COG1733	regulation of RNA biosynthetic process
L5465_12035	COG2249	NAD(P)H dehydrogenase (quinone) activity
L5465_12105	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L5465_12120	COG2329	Antibiotic biosynthesis monooxygenase
L5465_12155	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
L5465_12185	COG0427	acetyl-CoA hydrolase
L5465_12210	COG0659	secondary active sulfate transmembrane transporter activity
L5465_12215	COG4221	oxidoreductase activity
L5465_12220	COG2873	o-acetylhomoserine
L5465_12225	COG0488	(ABC) transporter
L5465_12310	COG0833	amino acid
L5465_12355	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
L5465_12360	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L5465_12375	COG2226	methyltransferase
L5465_12425	COG0067	glutamate synthase
L5465_12425	COG0069	glutamate synthase activity
L5465_12425	COG0070	glutamate synthase
L5465_12430	COG0493	'glutamate synthase
L5465_12440	COG1704	LemA family
L5465_12445	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
L5465_12460	COG3307	-O-antigen
L5465_12480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L5465_12495	COG0194	GDP metabolic process
L5465_12545	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
L5465_12565	COG5380	lipid catabolic process
L5465_12570	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
L5465_12595	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L5465_12600	COG0277	FAD linked oxidase domain protein
L5465_12610	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
L5465_12615	COG2249	NAD(P)H dehydrogenase (quinone) activity
L5465_12630	COG1289	transmembrane transporter activity
L5465_12640	COG0628	permease
L5465_12645	COG1192	Involved in chromosome partitioning
L5465_12675	COG0833	amino acid
L5465_12680	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L5465_12685	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L5465_12695	COG1012	belongs to the aldehyde dehydrogenase family
L5465_12735	COG0583	DNA-binding transcription factor activity
L5465_12755	COG1106	Psort location Cytoplasmic, score
L5465_12790	COG0517	IMP dehydrogenase activity
L5465_12795	COG1983	PspC domain protein
L5465_12805	COG1960	acyl-CoA dehydrogenase activity
L5465_12820	COG0408	coproporphyrinogen oxidase activity
L5465_12840	COG0513	Belongs to the DEAD box helicase family
L5465_12850	COG1127	ABC transporter
L5465_12855	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
L5465_12865	COG2854	intermembrane phospholipid transfer
L5465_12875	COG0598	Magnesium transport protein CorA
L5465_12885	COG0494	nUDIX hydrolase
L5465_12890	COG1040	competence protein
L5465_12915	COG1946	Acyl-CoA thioesterase
L5465_12920	COG1301	dicarboxylic acid transport
L5465_12935	COG1959	2 iron, 2 sulfur cluster binding
L5465_12940	COG1017	nitric oxide dioxygenase activity
L5465_12940	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L5465_12950	COG0433	COG0433 Predicted ATPase
L5465_12955	COG0626	cystathionine gamma-synthase activity
L5465_13110	COG1960	acyl-CoA dehydrogenase activity
L5465_13115	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
L5465_13145	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
L5465_13150	COG0339	signal peptide processing
L5465_13155	COG0557	exoribonuclease II activity
L5465_13200	COG0179	Fumarylacetoacetate (FAA) hydrolase
L5465_13205	COG2169	Transcriptional regulator
L5465_13210	COG0697	spore germination
L5465_13215	COG1295	ribonuclease BN
L5465_13250	COG1702	phosphate starvation-inducible protein PhoH
L5465_13260	COG0739	heme binding
L5465_13260	COG0741	lytic transglycosylase activity
L5465_13260	COG1196	nuclear chromosome segregation
L5465_13290	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
L5465_13295	COG1183	phosphatidylcholine synthase activity
L5465_13340	COG1960	acyl-CoA dehydrogenase activity
L5465_13345	COG1309	transcriptional regulator
L5465_13360	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L5465_13365	COG1960	acyl-CoA dehydrogenase activity
L5465_13385	COG2969	positive regulation of protein catabolic process
L5465_13395	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
L5465_13405	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
L5465_13410	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
L5465_13415	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L5465_13435	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L5465_13445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L5465_13450	COG1408	metallophosphoesterase
L5465_13520	COG1607	acyl-coa hydrolase
L5465_13550	COG2350	Protein conserved in bacteria
L5465_13565	COG3781	membrane
L5465_13575	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L5465_13580	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L5465_13590	COG1862	Preprotein translocase
L5465_13630	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
L5465_13645	COG0726	polysaccharide deacetylase
L5465_13650	COG0438	transferase activity, transferring glycosyl groups
L5465_13660	COG0438	transferase activity, transferring glycosyl groups
L5465_13675	COG2826	transposase and inactivated derivatives, IS30 family
L5465_13735	COG1960	acyl-CoA dehydrogenase activity
L5465_13740	COG1960	acyl-CoA dehydrogenase activity
L5465_13750	COG2205	protein histidine kinase activity
L5465_13755	COG0745	RESPONSE REGULATOR receiver
L5465_13760	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
L5465_13780	COG2096	Adenosyltransferase
L5465_13830	COG0285	dihydrofolate synthase activity
L5465_13850	COG0450	alkyl hydroperoxide reductase
L5465_13865	COG0477	Major facilitator Superfamily
L5465_13870	COG1272	protein, Hemolysin III
L5465_13880	COG2153	protein acetylation
L5465_13900	COG0183	Belongs to the thiolase family
L5465_13905	COG2207	Transcriptional regulator
L5465_13925	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L5465_13945	COG0183	Belongs to the thiolase family
L5465_13955	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
L5465_13955	COG2885	chlorophyll binding
L5465_13965	COG1690	Belongs to the RtcB family
L5465_13970	COG0833	amino acid
L5465_13980	COG2233	PERMEase
L5465_13985	COG1217	gtp-binding protein TYPA
L5465_14010	COG2094	Belongs to the DNA glycosylase MPG family
L5465_14015	COG4772	TonB-dependent receptor
L5465_14020	COG1902	pentaerythritol trinitrate reductase activity
L5465_14035	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L5465_14040	COG0354	folic acid binding
L5465_14050	COG3189	MarR family transcriptional regulator
L5465_14055	COG2824	Alkylphosphonate utilization operon protein PhnA
L5465_14060	COG3422	double-strand break repair
L5465_14100	COG0840	transmembrane signaling receptor activity
L5465_14120	COG5510	response to toxic substance
L5465_14130	COG2832	Protein of unknown function (DUF454)
L5465_14135	COG1376	ErfK ybiS ycfS ynhG family protein
L5465_14175	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
L5465_14185	COG1289	transmembrane transporter activity
L5465_14190	COG2814	Major facilitator Superfamily
L5465_14210	COG1115	amino acid carrier protein
L5465_14215	COG1752	Esterase of the alpha-beta hydrolase superfamily
L5465_14220	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L5465_14225	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
L5465_14230	COG3590	peptidase
L5465_14255	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L5465_14265	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L5465_14270	COG1077	Cell shape determining protein MreB Mrl
L5465_14275	COG1792	Involved in formation and maintenance of cell shape
L5465_14280	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
L5465_14285	COG0424	maF-like protein
L5465_14290	COG1530	ribonuclease E activity
L5465_14300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L5465_14310	COG0560	Phosphoserine phosphatase
L5465_14320	COG2249	NAD(P)H dehydrogenase (quinone) activity
L5465_14345	COG2207	Transcriptional regulator
L5465_14365	COG1113	amino acid transport
L5465_14370	COG2828	Protein conserved in bacteria
L5465_14375	COG0142	geranyltranstransferase activity
L5465_14380	COG2315	Protein conserved in bacteria
L5465_14395	COG1752	Esterase of the alpha-beta hydrolase superfamily
L5465_14415	COG2194	sulfuric ester hydrolase activity
L5465_14420	COG0745	RESPONSE REGULATOR receiver
L5465_14425	COG0642	Histidine kinase
L5465_14435	COG0004	ammonium transporteR
L5465_14440	COG0583	DNA-binding transcription factor activity
L5465_14460	COG0525	valine-tRNA ligase activity
L5465_14470	COG1028	Short-chain dehydrogenase reductase Sdr
L5465_14480	COG0393	Putative heavy-metal-binding
L5465_14485	COG0393	Putative heavy-metal-binding
L5465_14490	COG1538	Outer membrane efflux protein
L5465_14500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L5465_14505	COG0671	phosphoesterase, PA-phosphatase related
L5465_14535	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L5465_14550	COG1648	precorrin-2 dehydrogenase activity
L5465_14550	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L5465_14555	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L5465_14560	COG1733	regulation of RNA biosynthetic process
L5465_14570	COG0531	amino acid
L5465_14585	COG0321	lipoyl(octanoyl) transferase activity
L5465_14590	COG2921	Belongs to the UPF0250 family
L5465_14625	COG2009	succinate dehydrogenase
L5465_14630	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
L5465_14635	COG1053	succinate dehydrogenase
L5465_14640	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L5465_14665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L5465_14685	COG2354	Protein conserved in bacteria
L5465_14690	COG2321	neutral zinc metallopeptidase
L5465_14710	COG2843	Capsule synthesis protein
L5465_14725	COG0589	response to stress
L5465_14745	COG0505	Belongs to the CarA family
L5465_14770	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L5465_14775	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L5465_14825	COG0477	Major facilitator Superfamily
L5465_14830	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
L5465_14845	COG1597	lipid kinase activity
L5465_14850	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L5465_14875	COG0584	glycerophosphoryl diester phosphodiesterase
L5465_14895	COG0741	lytic transglycosylase activity
L5465_14915	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
L5465_14930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L5465_14940	COG3811	Belongs to the UPF0386 family
L5465_14970	COG0778	Nitroreductase
L5465_14985	COG1929	Belongs to the glycerate kinase type-1 family
L5465_14990	COG0243	molybdopterin cofactor binding
L5465_14995	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L5465_15000	COG3339	Conserved Protein
L5465_15010	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
L5465_15025	COG1113	amino acid transport
L5465_15035	COG0019	diaminopimelate decarboxylase activity
L5465_15045	COG1280	lysine exporter protein (LysE YggA)
L5465_15050	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L5465_15080	COG0463	Glycosyl transferase, family 2
L5465_15100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L5465_15135	COG4591	ABC-type transport system involved in lipoprotein release permease component
L5465_15140	COG1136	(ABC) transporter
L5465_15145	COG0658	competence protein
L5465_15145	COG2333	competence protein COMEC
L5465_15155	COG0616	signal peptide processing
L5465_15155	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L5465_15160	COG0596	Alpha beta hydrolase
L5465_15165	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L5465_15175	COG0628	permease
L5465_15210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L5465_15230	COG0823	Involved in the tonB-independent uptake of proteins
L5465_15250	COG0824	Thioesterase
L5465_15255	COG1473	amidohydrolase
L5465_15275	COG0047	phosphoribosylformylglycinamidine synthase activity
L5465_15275	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L5465_15280	COG2814	Major facilitator Superfamily
L5465_15290	COG1024	Enoyl-CoA hydratase
L5465_15295	COG1051	belongs to the nudix hydrolase family
L5465_15295	COG1056	cytidyltransferase-related domain
L5465_15305	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L5465_15320	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
L5465_15335	COG4625	pathogenesis
L5465_15340	COG0583	DNA-binding transcription factor activity
L5465_15345	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
L5465_15350	COG4208	sulfate ABC transporter
L5465_15355	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
L5465_15365	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
L5465_15370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L5465_15375	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L5465_15395	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L5465_15410	COG0681	Belongs to the peptidase S26 family
L5465_15425	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L5465_15435	COG1381	Involved in DNA repair and RecF pathway recombination
L5465_15440	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
L5465_15450	COG4221	oxidoreductase activity
L5465_15480	COG0436	Aminotransferase
L5465_15500	COG0556	nucleotide-excision repair
L5465_15555	COG2070	2-Nitropropane dioxygenase
L5465_15585	COG1215	transferase activity, transferring glycosyl groups
L5465_15600	COG0415	Belongs to the DNA photolyase family
L5465_15610	COG1252	NADH dehydrogenase
L5465_15615	COG1686	Belongs to the peptidase S11 family
L5465_15630	COG1187	pseudouridine synthase activity
L5465_15655	COG0477	Major facilitator Superfamily
L5465_15660	COG0583	DNA-binding transcription factor activity
L5465_15675	COG0612	Peptidase, M16
L5465_15705	COG1203	CRISPR-associated helicase, Cas3
L5465_15730	COG0352	thiamine-phosphate diphosphorylase activity
L5465_15765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L5465_15780	COG1309	transcriptional regulator
L5465_15790	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L5465_15795	COG0076	glutamate decarboxylase activity
L5465_15805	COG1522	sequence-specific DNA binding
L5465_15810	COG3961	Belongs to the TPP enzyme family
L5465_15815	COG1113	amino acid transport
L5465_15820	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L5465_15825	COG0573	inorganic phosphate transmembrane transporter activity
L5465_15835	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L5465_15875	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L5465_15880	COG1686	Belongs to the peptidase S11 family
L5465_15905	COG0583	DNA-binding transcription factor activity
L5465_15910	COG1067	ATP-dependent peptidase activity
L5465_15915	COG2211	Major facilitator Superfamily
L5465_15935	COG4943	cyclic-guanylate-specific phosphodiesterase activity
L5465_15955	COG1966	Carbon starvation protein
L5465_15960	COG2879	small protein
L5465_16055	COG1802	Transcriptional regulator
L5465_16055	COG4626	Terminase
L5465_16060	COG4695	Portal protein
L5465_16180	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L5465_16225	COG1741	Belongs to the pirin family
L5465_16235	COG2964	Protein conserved in bacteria
L5465_16250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L5465_16255	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L5465_16260	COG4605	iron ion homeostasis
L5465_16265	COG4604	ABC transporter, ATP-binding protein
L5465_16270	COG4607	ABC-type enterochelin transport system periplasmic component
L5465_16275	COG4774	siderophore transport
L5465_16285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L5465_16290	COG1021	2,3-dihydroxybenzoate-AMP ligase
L5465_16295	COG1535	isochorismatase
L5465_16295	COG3433	isochorismatase activity
L5465_16305	COG1132	(ABC) transporter
L5465_16310	COG1132	(ABC) transporter
L5465_16315	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
L5465_16320	COG2977	Belongs to the P-Pant transferase superfamily
L5465_16325	COG1169	isochorismate synthase
L5465_16340	COG3739	integral membrane protein
L5465_16365	COG0302	gtp cyclohydrolase
L5465_16375	COG1529	Aldehyde oxidase and xanthine dehydrogenase
L5465_16385	COG2840	Smr protein MutS2
L5465_16405	COG0308	aminopeptidase N
L5465_16410	COG0512	Glutamine amidotransferase of anthranilate synthase
L5465_16425	COG0174	glutamine synthetase
L5465_16435	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
L5465_16470	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L5465_16475	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L5465_16480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L5465_16500	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L5465_16505	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L5465_16510	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
L5465_16525	COG1960	acyl-CoA dehydrogenase activity
L5465_16530	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L5465_16535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L5465_16545	COG2223	nitrite transmembrane transporter activity
L5465_16555	COG0024	Methionine aminopeptidase
L5465_16560	COG0052	Belongs to the universal ribosomal protein uS2 family
L5465_16575	COG2207	Transcriptional regulator
L5465_16600	COG2951	lytic endotransglycosylase activity
L5465_16605	COG0772	Belongs to the SEDS family
L5465_16620	COG0842	Transport permease protein
L5465_16625	COG1131	(ABC) transporter
L5465_16630	COG0582	viral genome integration into host DNA
L5465_16700	COG0305	Participates in initiation and elongation during chromosome replication
L5465_16785	COG4695	Portal protein
L5465_16845	COG0741	lytic transglycosylase activity
L5465_16845	COG0739	heme binding
L5465_16845	COG1196	nuclear chromosome segregation
L5465_16955	COG0006	proline dipeptidase activity
L5465_16960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L5465_16965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L5465_16985	COG1279	arginine transmembrane transporter activity
L5465_16990	COG0583	DNA-binding transcription factor activity
L5465_17030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L5465_17035	COG1388	LysM domain
L5465_17035	COG0741	lytic transglycosylase activity
L5465_17035	COG1388	LysM domain
L5465_17035	COG0741	lytic transglycosylase activity
L5465_17045	COG4174	ABC transporter (Permease)
L5465_17050	COG4239	(ABC) transporter, permease
L5465_17055	COG4172	Belongs to the ABC transporter superfamily
L5465_17075	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L5465_17085	COG2203	Gaf domain
L5465_17085	COG5001	Diguanylate cyclase
L5465_17085	COG3706	GGDEF domain
L5465_17085	COG4251	negative regulation of phosphorylation
L5465_17100	COG1902	pentaerythritol trinitrate reductase activity
L5465_17100	COG0446	pyridine nucleotide-disulphide oxidoreductase
L5465_17130	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L5465_17140	COG0583	DNA-binding transcription factor activity
L5465_17145	COG2814	Major facilitator Superfamily
L5465_17160	COG1012	belongs to the aldehyde dehydrogenase family
L5465_17165	COG1454	alcohol dehydrogenase
L5465_17170	COG3485	protocatechuate 3,4-dioxygenase
L5465_17185	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L5465_17190	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L5465_17195	COG0183	Belongs to the thiolase family
L5465_17230	COG1113	amino acid transport
L5465_17240	COG0531	amino acid
L5465_17260	COG1012	belongs to the aldehyde dehydrogenase family
L5465_17280	COG1113	amino acid transport
L5465_17295	COG0697	spore germination
L5465_17300	COG2721	sulfolactate sulfo-lyase activity
L5465_17305	COG2271	Major facilitator Superfamily
L5465_17310	COG4948	Mandelate Racemase Muconate Lactonizing
L5465_17320	COG1012	belongs to the aldehyde dehydrogenase family
L5465_17325	COG2186	Transcriptional regulator
L5465_17350	COG1960	acyl-CoA dehydrogenase activity
L5465_17360	COG1012	belongs to the aldehyde dehydrogenase family
L5465_17365	COG1024	Enoyl-CoA hydratase
L5465_17370	COG2814	Major facilitator Superfamily
L5465_17385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L5465_17400	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L5465_17445	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
L5465_17460	COG0583	DNA-binding transcription factor activity
L5465_17465	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
L5465_17470	COG2072	flavoprotein involved in K transport
L5465_17475	COG0300	oxidoreductase activity
L5465_17485	COG1309	transcriptional regulator
L5465_17490	COG1741	Belongs to the pirin family
L5465_17505	COG2072	flavoprotein involved in K transport
L5465_17515	COG2252	PERMEase
L5465_17520	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
L5465_17525	COG3038	cytochrome b561
L5465_17535	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
L5465_17545	COG0527	aspartate kinase activity
L5465_17555	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L5465_17565	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
L5465_17580	COG0667	Aldo Keto reductase
L5465_17595	COG1765	OsmC-like protein
L5465_17610	COG0542	response to heat
L5465_17645	COG2885	chlorophyll binding
L5465_17655	COG0625	glutathione transferase activity
L5465_17660	COG0220	tRNA (guanine-N7-)-methyltransferase activity
L5465_17680	COG3634	alkyl hydroperoxide reductase activity
L5465_17695	COG0243	molybdopterin cofactor binding
L5465_17710	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
L5465_17720	COG0450	alkyl hydroperoxide reductase
L5465_17725	COG1643	Atp-dependent helicase
L5465_17740	COG2814	Major facilitator Superfamily
L5465_17745	COG3135	benzoate transporter
L5465_17750	COG1028	Short-chain dehydrogenase reductase Sdr
L5465_17755	COG0633	Ferredoxin
L5465_17755	COG0543	2 iron, 2 sulfur cluster binding
L5465_17765	COG4638	Rieske (2fe-2S)
L5465_17775	COG0583	DNA-binding transcription factor activity
L5465_17785	COG2871	sodium ion transport
L5465_17870	COG1570	exodeoxyribonuclease VII activity
L5465_17900	COG1280	lysine exporter protein (LysE YggA)
L5465_17905	COG1278	Cold shock
L5465_17940	COG2814	Major facilitator Superfamily
L5465_18005	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
L5465_18015	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
L5465_18020	COG1137	ATPase activity
L5465_18065	COG4122	O-methyltransferase activity
L5465_18075	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
L5465_18090	COG1522	sequence-specific DNA binding
L5465_18095	COG5006	permease, DMT superfamily
L5465_18105	COG1560	Kdo2-lipid A biosynthetic process
L5465_18110	COG0598	Magnesium transport protein CorA
L5465_18130	COG2814	Major facilitator Superfamily
L5465_18150	COG1250	3-hydroxyacyl-CoA dehydrogenase
L5465_18170	COG0583	DNA-binding transcription factor activity
L5465_18175	COG1914	H( )-stimulated, divalent metal cation uptake system
L5465_18195	COG4770	biotin carboxylase activity
L5465_18200	COG0038	chloride channel
L5465_18205	COG2831	hemolysin activation secretion protein
L5465_18210	COG3210	domain, Protein
L5465_18220	COG1309	transcriptional regulator
L5465_18230	COG1063	alcohol dehydrogenase
L5465_18245	COG0439	Biotin carboxylase
L5465_18250	COG2249	NAD(P)H dehydrogenase (quinone) activity
L5465_18255	COG1733	regulation of RNA biosynthetic process
L5465_18265	COG0864	Transcriptional regulator
L5465_18275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L5465_18280	COG1116	anion transmembrane transporter activity
L5465_18435	COG0590	tRNA wobble adenosine to inosine editing
L5465_18440	COG2807	transmembrane transport
L5465_18455	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
L5465_18465	COG0789	Transcriptional regulator
L5465_18475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L5465_18495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L5465_18520	COG1012	belongs to the aldehyde dehydrogenase family
L5465_18525	COG0531	amino acid
L5465_18530	COG1760	l-serine dehydratase
L5465_18535	COG1012	belongs to the aldehyde dehydrogenase family
L5465_18535	COG2030	dehydratase
L5465_18540	COG3396	Phenylacetate-CoA oxygenase
L5465_18545	COG3460	Phenylacetate-CoA oxygenase
L5465_18550	COG3396	Phenylacetate-CoA oxygenase
L5465_18555	COG2151	metal-sulfur cluster biosynthetic enzyme
L5465_18560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L5465_18565	COG1024	Enoyl-CoA hydratase
L5465_18570	COG1024	Enoyl-CoA hydratase
L5465_18575	COG1250	3-hydroxyacyl-CoA dehydrogenase
L5465_18580	COG0183	Belongs to the thiolase family
L5465_18585	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
L5465_18590	COG3327	negative regulation of DNA-templated transcription, initiation
L5465_18600	COG2050	protein possibly involved in aromatic compounds catabolism
L5465_18610	COG0556	nucleotide-excision repair
L5465_18625	COG2207	Transcriptional regulator
L5465_18640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L5465_18645	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L5465_18650	COG2271	Major facilitator Superfamily
L5465_18655	COG0753	catalase activity
L5465_18660	COG3038	cytochrome b561
L5465_18680	COG2267	carboxylic ester hydrolase activity
L5465_18685	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L5465_18690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L5465_18695	COG1012	belongs to the aldehyde dehydrogenase family
L5465_18705	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L5465_18715	COG1012	belongs to the aldehyde dehydrogenase family
L5465_18720	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L5465_18725	COG0583	DNA-binding transcription factor activity
L5465_18735	COG1414	Transcriptional regulator
L5465_18740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L5465_18750	COG1840	ABC-type Fe3 transport system, periplasmic component
L5465_18755	COG3842	ATPase activity
L5465_18770	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L5465_18775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L5465_18780	COG2814	Major facilitator Superfamily
L5465_18785	COG1960	acyl-CoA dehydrogenase activity
L5465_18800	COG1024	Enoyl-CoA hydratase
L5465_18810	COG2814	Major facilitator Superfamily
L5465_18820	COG0183	Belongs to the thiolase family
L5465_18825	COG1250	3-hydroxyacyl-CoA dehydrogenase
L5465_18830	COG1028	Short-chain dehydrogenase reductase Sdr
L5465_18835	COG1024	Enoyl-CoA hydratase
L5465_18840	COG1960	acyl-CoA dehydrogenase activity
L5465_18845	COG2814	Major facilitator Superfamily
L5465_18850	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L5465_18855	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L5465_18865	COG2814	Major facilitator Superfamily
L5465_18875	COG1960	acyl-CoA dehydrogenase activity
L5465_18890	COG0583	DNA-binding transcription factor activity
L5465_18900	COG4770	biotin carboxylase activity
L5465_18905	COG1024	Enoyl-CoA hydratase
L5465_18910	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L5465_18915	COG1960	acyl-CoA dehydrogenase activity
L5465_18920	COG1309	transcriptional regulator
L5465_18925	COG0318	PFAM AMP-dependent synthetase and ligase
L5465_18945	COG0583	DNA-binding transcription factor activity
L5465_18995	COG1028	Short-chain dehydrogenase reductase Sdr
L5465_19020	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L5465_19040	COG2205	protein histidine kinase activity
L5465_19040	COG0784	Response regulator, receiver
L5465_19080	COG0765	amino acid transport
L5465_19085	COG0765	amino acid transport
L5465_19095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L5465_19100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L5465_19115	COG1280	lysine exporter protein (LysE YggA)
L5465_19130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L5465_19135	COG1045	serine acetyltransferase
L5465_19150	COG0583	DNA-binding transcription factor activity
L5465_19155	COG0625	glutathione transferase activity
L5465_19160	COG0625	glutathione transferase activity
L5465_19165	COG0583	DNA-binding transcription factor activity
L5465_19175	COG1346	cytolysis
L5465_19200	COG0300	oxidoreductase activity
L5465_19210	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
L5465_19215	COG3052	prosthetic group binding
L5465_19235	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L5465_19255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L5465_19265	COG1294	oxidase, subunit
L5465_19270	COG1271	oxidase subunit
L5465_19290	COG0477	Major facilitator Superfamily
L5465_19300	COG4521	taurine ABC transporter
L5465_19305	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
L5465_19310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L5465_19315	COG2175	clavaminate synthase activity
L5465_19325	COG1953	Uracil, thiamine, allantoin
L5465_19335	COG0583	DNA-binding transcription factor activity
L5465_19345	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
L5465_19360	COG0640	Transcriptional regulator
L5465_19365	COG0798	PFAM Bile acid sodium symporter
L5465_19385	COG3634	alkyl hydroperoxide reductase activity
L5465_19425	COG0436	Aminotransferase
L5465_19435	COG0386	Belongs to the glutathione peroxidase family
L5465_19475	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L5465_19500	COG0012	GTP binding
L5465_19505	COG2011	ABC-type metal ion transport system permease component
L5465_19510	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L5465_19520	COG1464	Belongs to the NlpA lipoprotein family
L5465_19550	COG0765	amino acid transport
L5465_19555	COG0765	amino acid transport
L5465_19560	COG1126	abc transporter atp-binding protein
L5465_19570	COG1522	sequence-specific DNA binding
L5465_19585	COG1309	transcriptional regulator
L5465_19605	COG0583	DNA-binding transcription factor activity
L5465_19615	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L5465_19625	COG0697	spore germination
L5465_19655	COG3539	Fimbrial protein
L5465_19680	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
L5465_19680	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
L5465_19725	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L5465_19735	COG2353	YceI-like domain
L5465_19745	COG3698	Phosphodiester glycosidase
L5465_19760	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L5465_19765	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L5465_19765	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L5465_19765	COG0506	proline dehydrogenase activity
L5465_19775	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L5465_19780	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
L5465_19800	COG1132	(ABC) transporter
L5465_19805	COG3122	Protein conserved in bacteria
L5465_19810	COG3619	membrane
L5465_19820	COG0640	Transcriptional regulator
L5465_19830	COG2850	peptidyl-arginine hydroxylation
L5465_19835	COG0424	maF-like protein
L5465_19855	COG0191	fructose-bisphosphate aldolase activity
L5465_19875	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L5465_19885	COG1192	Involved in chromosome partitioning
L5465_19890	COG1475	DNA binding
L5465_19895	COG0811	peptide transport
L5465_19905	COG1132	(ABC) transporter
L5465_19910	COG1663	tetraacyldisaccharide 4'-kinase activity
L5465_19930	COG0084	hydrolase, TatD family'
L5465_19995	COG0776	regulation of translation
L5465_20025	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
L5465_20030	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L5465_20070	COG4166	transmembrane transport
L5465_20080	COG0339	signal peptide processing
L5465_20090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L5465_20125	COG0702	epimerase
L5465_20130	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L5465_20150	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L5465_20180	COG0316	Belongs to the HesB IscA family
L5465_20185	COG0822	iron-sulfur transferase activity
L5465_20210	COG0776	regulation of translation
L5465_20215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L5465_20220	COG2207	Transcriptional regulator
L5465_20225	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L5465_20230	COG1960	acyl-CoA dehydrogenase activity
L5465_20235	COG1960	acyl-CoA dehydrogenase activity
L5465_20250	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L5465_20270	COG4264	IucA IucC family
L5465_20275	COG4264	IucA IucC family
L5465_20285	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L5465_20315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L5465_20330	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
L5465_20335	COG0406	alpha-ribazole phosphatase activity
L5465_20350	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L5465_20355	COG0730	response to heat
L5465_20375	COG4773	Receptor
L5465_20380	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L5465_20395	COG1131	(ABC) transporter
L5465_20400	COG0842	Transport permease protein
L5465_20405	COG0842	Transport permease protein
L5465_20460	COG2226	methyltransferase
L5465_20485	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
L5465_20565	COG2826	transposase and inactivated derivatives, IS30 family
L5465_20690	COG0739	heme binding
L5465_20730	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L5465_20740	COG1192	Involved in chromosome partitioning
L5465_20790	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L5465_20940	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
L5465_21020	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L5465_21055	COG0501	Belongs to the peptidase M48B family