locus-tag	class	description
KSA16_000010	COG0592	DNA-directed DNA polymerase activity
KSA16_000020	COG0187	DNA topoisomerase II activity
KSA16_000030	COG0586	Pfam SNARE associated Golgi protein
KSA16_000035	COG0488	(ABC) transporter
KSA16_000060	COG0596	Alpha beta hydrolase
KSA16_000065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KSA16_000070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KSA16_000115	COG0733	neurotransmitter:sodium symporter activity
KSA16_000125	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KSA16_000155	COG2233	PERMEase
KSA16_000170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KSA16_000205	COG2814	Major facilitator Superfamily
KSA16_000210	COG0656	L-ascorbic acid biosynthetic process
KSA16_000215	COG0583	DNA-binding transcription factor activity
KSA16_000230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KSA16_000235	COG1064	alcohol dehydrogenase
KSA16_000240	COG2818	Glycosylase
KSA16_000255	COG1194	a g-specific adenine glycosylase
KSA16_000275	COG2983	Belongs to the UPF0260 family
KSA16_000280	COG2133	pyrroloquinoline quinone binding
KSA16_000285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KSA16_000290	COG2116	formate transmembrane transporter activity
KSA16_000310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KSA16_000315	COG1335	isochorismatase
KSA16_000320	COG0385	Bile acid
KSA16_000325	COG0534	Mate efflux family protein
KSA16_000330	COG1683	Conserved Protein
KSA16_000350	COG0625	glutathione transferase activity
KSA16_000360	COG1113	amino acid transport
KSA16_000370	COG0523	cobalamin synthesis protein
KSA16_000380	COG2188	Transcriptional regulator
KSA16_000410	COG0010	Belongs to the arginase family
KSA16_000425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KSA16_000430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KSA16_000440	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KSA16_000445	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KSA16_000545	COG0534	Mate efflux family protein
KSA16_000550	COG0436	Aminotransferase
KSA16_000555	COG2733	membrane
KSA16_000570	COG2918	glutathione biosynthetic process
KSA16_000585	COG0791	NLP P60 protein
KSA16_000585	COG1388	LysM domain
KSA16_000600	COG3150	esterase
KSA16_000610	COG1028	Short-chain dehydrogenase reductase Sdr
KSA16_000615	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
KSA16_000625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KSA16_000635	COG2233	PERMEase
KSA16_000640	COG2351	hydroxyisourate hydrolase activity
KSA16_000675	COG3706	GGDEF domain
KSA16_000690	COG1393	Belongs to the ArsC family
KSA16_000695	COG0708	Exodeoxyribonuclease III
KSA16_000715	COG0189	ligase activity
KSA16_000735	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KSA16_000745	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KSA16_000760	COG4942	peptidase
KSA16_000770	COG0508	dehydrogenase complex catalyzes the overall conversion of
KSA16_000780	COG2119	membrane
KSA16_000785	COG4774	siderophore transport
KSA16_000790	COG0426	domain, Protein
KSA16_000790	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KSA16_000815	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KSA16_000835	COG1902	pentaerythritol trinitrate reductase activity
KSA16_000840	COG1519	Transferase
KSA16_000845	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KSA16_000850	COG0668	transmembrane transport
KSA16_000860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KSA16_000865	COG1335	isochorismatase
KSA16_000870	COG1522	sequence-specific DNA binding
KSA16_000875	COG3328	transposase activity
KSA16_000900	COG0784	Response regulator, receiver
KSA16_000900	COG2205	protein histidine kinase activity
KSA16_000900	COG2198	Histidine kinase
KSA16_000905	COG3162	membrane
KSA16_000910	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KSA16_000920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KSA16_000940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KSA16_000945	COG1309	transcriptional regulator
KSA16_000965	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KSA16_000965	COG0351	phosphomethylpyrimidine kinase
KSA16_000965	COG0352	thiamine-phosphate diphosphorylase activity
KSA16_000975	COG2814	Major facilitator Superfamily
KSA16_000990	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KSA16_001000	COG1113	amino acid transport
KSA16_001010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KSA16_001015	COG1012	belongs to the aldehyde dehydrogenase family
KSA16_001025	COG1335	isochorismatase
KSA16_001055	COG2814	Major facilitator Superfamily
KSA16_001060	COG0583	DNA-binding transcription factor activity
KSA16_001080	COG0667	Aldo Keto reductase
KSA16_001115	COG1733	regulation of RNA biosynthetic process
KSA16_001120	COG2249	NAD(P)H dehydrogenase (quinone) activity
KSA16_001185	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KSA16_001200	COG2329	Antibiotic biosynthesis monooxygenase
KSA16_001230	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KSA16_001260	COG0427	acetyl-CoA hydrolase
KSA16_001285	COG0659	secondary active sulfate transmembrane transporter activity
KSA16_001290	COG4221	oxidoreductase activity
KSA16_001295	COG2873	o-acetylhomoserine
KSA16_001300	COG0488	(ABC) transporter
KSA16_001385	COG0833	amino acid
KSA16_001430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KSA16_001435	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KSA16_001450	COG2226	methyltransferase
KSA16_001500	COG0067	glutamate synthase
KSA16_001500	COG0070	glutamate synthase
KSA16_001500	COG0069	glutamate synthase activity
KSA16_001505	COG0493	'glutamate synthase
KSA16_001515	COG1704	LemA family
KSA16_001520	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KSA16_001540	COG3307	-O-antigen
KSA16_001560	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KSA16_001575	COG0194	GDP metabolic process
KSA16_001625	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KSA16_001645	COG5380	lipid catabolic process
KSA16_001650	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KSA16_001675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KSA16_001680	COG0277	FAD linked oxidase domain protein
KSA16_001690	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KSA16_001695	COG2249	NAD(P)H dehydrogenase (quinone) activity
KSA16_001710	COG1289	transmembrane transporter activity
KSA16_001720	COG0628	permease
KSA16_001725	COG1192	Involved in chromosome partitioning
KSA16_001755	COG0833	amino acid
KSA16_001760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KSA16_001765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KSA16_001775	COG1012	belongs to the aldehyde dehydrogenase family
KSA16_001815	COG0583	DNA-binding transcription factor activity
KSA16_001860	COG0517	IMP dehydrogenase activity
KSA16_001865	COG1983	PspC domain protein
KSA16_001875	COG1960	acyl-CoA dehydrogenase activity
KSA16_001890	COG0408	coproporphyrinogen oxidase activity
KSA16_001910	COG0513	Belongs to the DEAD box helicase family
KSA16_001920	COG1127	ABC transporter
KSA16_001925	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KSA16_001935	COG2854	intermembrane phospholipid transfer
KSA16_001945	COG0598	Magnesium transport protein CorA
KSA16_001955	COG0494	nUDIX hydrolase
KSA16_001960	COG1040	competence protein
KSA16_001965	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KSA16_001985	COG1946	Acyl-CoA thioesterase
KSA16_001990	COG1301	dicarboxylic acid transport
KSA16_002005	COG1959	2 iron, 2 sulfur cluster binding
KSA16_002010	COG1017	nitric oxide dioxygenase activity
KSA16_002010	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KSA16_002015	COG0433	COG0433 Predicted ATPase
KSA16_002020	COG0626	cystathionine gamma-synthase activity
KSA16_002175	COG1960	acyl-CoA dehydrogenase activity
KSA16_002180	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KSA16_002210	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KSA16_002215	COG0339	signal peptide processing
KSA16_002220	COG0557	exoribonuclease II activity
KSA16_002265	COG0179	Fumarylacetoacetate (FAA) hydrolase
KSA16_002270	COG2169	Transcriptional regulator
KSA16_002275	COG0697	spore germination
KSA16_002280	COG1295	ribonuclease BN
KSA16_002315	COG1702	phosphate starvation-inducible protein PhoH
KSA16_002325	COG1196	nuclear chromosome segregation
KSA16_002325	COG0739	heme binding
KSA16_002325	COG0741	lytic transglycosylase activity
KSA16_002355	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KSA16_002360	COG1183	phosphatidylcholine synthase activity
KSA16_002405	COG1960	acyl-CoA dehydrogenase activity
KSA16_002410	COG1309	transcriptional regulator
KSA16_002425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KSA16_002430	COG1960	acyl-CoA dehydrogenase activity
KSA16_002450	COG2969	positive regulation of protein catabolic process
KSA16_002460	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KSA16_002475	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KSA16_002480	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KSA16_002500	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KSA16_002510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KSA16_002515	COG1408	metallophosphoesterase
KSA16_002525	COG2199	diguanylate cyclase activity
KSA16_002585	COG1607	acyl-coa hydrolase
KSA16_002615	COG2350	Protein conserved in bacteria
KSA16_002625	COG0613	PHP domain protein
KSA16_002630	COG3781	membrane
KSA16_002640	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KSA16_002645	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KSA16_002655	COG1862	Preprotein translocase
KSA16_002705	COG2205	protein histidine kinase activity
KSA16_002710	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KSA16_002730	COG0726	polysaccharide deacetylase
KSA16_002735	COG0463	Glycosyl transferase, family 2
KSA16_002740	COG0438	transferase activity, transferring glycosyl groups
KSA16_002805	COG0625	glutathione transferase activity
KSA16_002810	COG0583	DNA-binding transcription factor activity
KSA16_002815	COG1960	acyl-CoA dehydrogenase activity
KSA16_002820	COG1960	acyl-CoA dehydrogenase activity
KSA16_002830	COG2205	protein histidine kinase activity
KSA16_002835	COG0745	RESPONSE REGULATOR receiver
KSA16_002840	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KSA16_002860	COG2096	Adenosyltransferase
KSA16_002910	COG0285	dihydrofolate synthase activity
KSA16_002930	COG0450	alkyl hydroperoxide reductase
KSA16_002945	COG0477	Major facilitator Superfamily
KSA16_002950	COG1272	protein, Hemolysin III
KSA16_002980	COG0183	Belongs to the thiolase family
KSA16_002985	COG2207	Transcriptional regulator
KSA16_003005	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KSA16_003025	COG0183	Belongs to the thiolase family
KSA16_003035	COG2885	chlorophyll binding
KSA16_003035	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KSA16_003045	COG1690	Belongs to the RtcB family
KSA16_003050	COG0833	amino acid
KSA16_003060	COG2233	PERMEase
KSA16_003065	COG1217	gtp-binding protein TYPA
KSA16_003090	COG2094	Belongs to the DNA glycosylase MPG family
KSA16_003110	COG1902	pentaerythritol trinitrate reductase activity
KSA16_003125	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KSA16_003130	COG0354	folic acid binding
KSA16_003140	COG3189	MarR family transcriptional regulator
KSA16_003145	COG2824	Alkylphosphonate utilization operon protein PhnA
KSA16_003150	COG3422	double-strand break repair
KSA16_003190	COG0840	transmembrane signaling receptor activity
KSA16_003210	COG5510	response to toxic substance
KSA16_003220	COG2832	Protein of unknown function (DUF454)
KSA16_003225	COG1376	ErfK ybiS ycfS ynhG family protein
KSA16_003265	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KSA16_003275	COG1289	transmembrane transporter activity
KSA16_003280	COG2814	Major facilitator Superfamily
KSA16_003300	COG1115	amino acid carrier protein
KSA16_003305	COG1752	Esterase of the alpha-beta hydrolase superfamily
KSA16_003310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KSA16_003315	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
KSA16_003345	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KSA16_003355	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KSA16_003360	COG1077	Cell shape determining protein MreB Mrl
KSA16_003365	COG1792	Involved in formation and maintenance of cell shape
KSA16_003370	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KSA16_003375	COG0424	maF-like protein
KSA16_003380	COG1530	ribonuclease E activity
KSA16_003390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KSA16_003400	COG0560	Phosphoserine phosphatase
KSA16_003410	COG2249	NAD(P)H dehydrogenase (quinone) activity
KSA16_003435	COG2207	Transcriptional regulator
KSA16_003455	COG1113	amino acid transport
KSA16_003460	COG2828	Protein conserved in bacteria
KSA16_003465	COG0142	geranyltranstransferase activity
KSA16_003470	COG2315	Protein conserved in bacteria
KSA16_003485	COG1752	Esterase of the alpha-beta hydrolase superfamily
KSA16_003505	COG2194	sulfuric ester hydrolase activity
KSA16_003510	COG0745	RESPONSE REGULATOR receiver
KSA16_003515	COG0642	Histidine kinase
KSA16_003525	COG0004	ammonium transporteR
KSA16_003530	COG0583	DNA-binding transcription factor activity
KSA16_003550	COG0525	valine-tRNA ligase activity
KSA16_003560	COG1028	Short-chain dehydrogenase reductase Sdr
KSA16_003570	COG0393	Putative heavy-metal-binding
KSA16_003575	COG0393	Putative heavy-metal-binding
KSA16_003580	COG1538	Outer membrane efflux protein
KSA16_003590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KSA16_003595	COG0671	phosphoesterase, PA-phosphatase related
KSA16_003625	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KSA16_003640	COG1648	precorrin-2 dehydrogenase activity
KSA16_003640	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KSA16_003645	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KSA16_003650	COG1733	regulation of RNA biosynthetic process
KSA16_003660	COG0531	amino acid
KSA16_003675	COG0321	lipoyl(octanoyl) transferase activity
KSA16_003680	COG2921	Belongs to the UPF0250 family
KSA16_003720	COG2009	succinate dehydrogenase
KSA16_003725	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KSA16_003730	COG1053	succinate dehydrogenase
KSA16_003735	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KSA16_003760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KSA16_003780	COG2354	Protein conserved in bacteria
KSA16_003785	COG2321	neutral zinc metallopeptidase
KSA16_003810	COG2843	Capsule synthesis protein
KSA16_003825	COG0589	response to stress
KSA16_003845	COG0505	Belongs to the CarA family
KSA16_003870	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KSA16_003875	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KSA16_003925	COG0477	Major facilitator Superfamily
KSA16_003930	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KSA16_003945	COG1597	lipid kinase activity
KSA16_003950	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KSA16_003975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KSA16_003980	COG0584	glycerophosphoryl diester phosphodiesterase
KSA16_004000	COG0741	lytic transglycosylase activity
KSA16_004020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KSA16_004035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KSA16_004065	COG0778	Nitroreductase
KSA16_004080	COG1929	Belongs to the glycerate kinase type-1 family
KSA16_004085	COG0243	molybdopterin cofactor binding
KSA16_004090	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KSA16_004095	COG3339	Conserved Protein
KSA16_004105	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KSA16_004120	COG1113	amino acid transport
KSA16_004130	COG0019	diaminopimelate decarboxylase activity
KSA16_004140	COG1280	lysine exporter protein (LysE YggA)
KSA16_004145	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KSA16_004175	COG0463	Glycosyl transferase, family 2
KSA16_004195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KSA16_004230	COG4591	ABC-type transport system involved in lipoprotein release permease component
KSA16_004235	COG1136	(ABC) transporter
KSA16_004240	COG2333	competence protein COMEC
KSA16_004240	COG0658	competence protein
KSA16_004250	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KSA16_004250	COG0616	signal peptide processing
KSA16_004255	COG0596	Alpha beta hydrolase
KSA16_004260	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KSA16_004270	COG0628	permease
KSA16_004305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KSA16_004325	COG0823	Involved in the tonB-independent uptake of proteins
KSA16_004345	COG0824	Thioesterase
KSA16_004350	COG1473	amidohydrolase
KSA16_004370	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KSA16_004370	COG0047	phosphoribosylformylglycinamidine synthase activity
KSA16_004375	COG2814	Major facilitator Superfamily
KSA16_004385	COG1024	Enoyl-CoA hydratase
KSA16_004390	COG1051	belongs to the nudix hydrolase family
KSA16_004390	COG1056	cytidyltransferase-related domain
KSA16_004400	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KSA16_004415	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KSA16_004430	COG4625	pathogenesis
KSA16_004435	COG0583	DNA-binding transcription factor activity
KSA16_004440	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KSA16_004445	COG4208	sulfate ABC transporter
KSA16_004450	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KSA16_004460	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KSA16_004465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KSA16_004470	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KSA16_004490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KSA16_004505	COG0681	Belongs to the peptidase S26 family
KSA16_004520	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KSA16_004530	COG1381	Involved in DNA repair and RecF pathway recombination
KSA16_004535	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KSA16_004545	COG4221	oxidoreductase activity
KSA16_004575	COG0436	Aminotransferase
KSA16_004595	COG0556	nucleotide-excision repair
KSA16_004655	COG2070	2-Nitropropane dioxygenase
KSA16_004685	COG1215	transferase activity, transferring glycosyl groups
KSA16_004700	COG0415	Belongs to the DNA photolyase family
KSA16_004710	COG1252	NADH dehydrogenase
KSA16_004715	COG1686	Belongs to the peptidase S11 family
KSA16_004730	COG1187	pseudouridine synthase activity
KSA16_004755	COG0477	Major facilitator Superfamily
KSA16_004760	COG0583	DNA-binding transcription factor activity
KSA16_004765	COG1823	symporter activity
KSA16_004775	COG0612	Peptidase, M16
KSA16_004800	COG0352	thiamine-phosphate diphosphorylase activity
KSA16_004835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KSA16_004850	COG1309	transcriptional regulator
KSA16_004860	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KSA16_004865	COG0076	glutamate decarboxylase activity
KSA16_004875	COG1522	sequence-specific DNA binding
KSA16_004880	COG3961	Belongs to the TPP enzyme family
KSA16_004885	COG1113	amino acid transport
KSA16_004890	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KSA16_004895	COG0573	inorganic phosphate transmembrane transporter activity
KSA16_004905	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KSA16_004910	COG0616	signal peptide processing
KSA16_004945	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KSA16_004950	COG1686	Belongs to the peptidase S11 family
KSA16_004975	COG0583	DNA-binding transcription factor activity
KSA16_004980	COG1067	ATP-dependent peptidase activity
KSA16_005025	COG1966	Carbon starvation protein
KSA16_005030	COG2879	small protein
KSA16_005065	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KSA16_005065	COG2508	Transcriptional regulator
KSA16_005085	COG1113	amino acid transport
KSA16_005090	COG0583	DNA-binding transcription factor activity
KSA16_005095	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KSA16_005100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KSA16_005110	COG1012	belongs to the aldehyde dehydrogenase family
KSA16_005120	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KSA16_005125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KSA16_005125	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KSA16_005160	COG2814	Major facilitator Superfamily
KSA16_005165	COG4948	Mandelate Racemase Muconate Lactonizing
KSA16_005175	COG1309	transcriptional regulator
KSA16_005195	COG1741	Belongs to the pirin family
KSA16_005205	COG2964	Protein conserved in bacteria
KSA16_005220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KSA16_005225	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KSA16_005230	COG4605	iron ion homeostasis
KSA16_005235	COG4604	ABC transporter, ATP-binding protein
KSA16_005240	COG4607	ABC-type enterochelin transport system periplasmic component
KSA16_005245	COG4774	siderophore transport
KSA16_005255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KSA16_005260	COG1021	2,3-dihydroxybenzoate-AMP ligase
KSA16_005265	COG3433	isochorismatase activity
KSA16_005265	COG1535	isochorismatase
KSA16_005280	COG1132	(ABC) transporter
KSA16_005285	COG1132	(ABC) transporter
KSA16_005290	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KSA16_005300	COG1169	isochorismate synthase
KSA16_005315	COG3739	integral membrane protein
KSA16_005340	COG0302	gtp cyclohydrolase
KSA16_005350	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KSA16_005380	COG0308	aminopeptidase N
KSA16_005385	COG0512	Glutamine amidotransferase of anthranilate synthase
KSA16_005400	COG0174	glutamine synthetase
KSA16_005410	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KSA16_005450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KSA16_005455	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KSA16_005460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KSA16_005480	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KSA16_005485	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KSA16_005490	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KSA16_005505	COG1960	acyl-CoA dehydrogenase activity
KSA16_005510	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KSA16_005515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KSA16_005525	COG2223	nitrite transmembrane transporter activity
KSA16_005535	COG0024	Methionine aminopeptidase
KSA16_005540	COG0052	Belongs to the universal ribosomal protein uS2 family
KSA16_005555	COG2207	Transcriptional regulator
KSA16_005580	COG2951	lytic endotransglycosylase activity
KSA16_005585	COG0772	Belongs to the SEDS family
KSA16_005600	COG0842	Transport permease protein
KSA16_005605	COG1131	(ABC) transporter
KSA16_005650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KSA16_005665	COG4215	(ABC) transporter
KSA16_005670	COG4160	amino acid transport
KSA16_005675	COG4598	ABC transporter
KSA16_005685	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KSA16_005690	COG0826	peptidase U32
KSA16_005695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KSA16_005710	COG1720	tRNA m6t6A37 methyltransferase activity
KSA16_005720	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KSA16_005735	COG0642	Histidine kinase
KSA16_005745	COG0494	nUDIX hydrolase
KSA16_005755	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KSA16_005760	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KSA16_005765	COG3139	Protein of unknown function (DUF1315)
KSA16_005770	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KSA16_005775	COG1301	dicarboxylic acid transport
KSA16_005780	COG1960	acyl-CoA dehydrogenase activity
KSA16_005785	COG2819	hydrolase of the alpha beta superfamily
KSA16_005795	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KSA16_005805	COG2195	Cleaves the N-terminal amino acid of tripeptides
KSA16_005810	COG1234	tRNA 3'-trailer cleavage
KSA16_005840	COG2363	Small membrane protein
KSA16_005865	COG0513	Belongs to the DEAD box helicase family
KSA16_005875	COG0778	Nitroreductase
KSA16_005905	COG1286	toxin biosynthetic process
KSA16_005930	COG4783	chaperone-mediated protein folding
KSA16_005935	COG1610	YqeY-like protein
KSA16_006035	COG3111	PFAM Bacterial OB fold (BOF) protein
KSA16_006060	COG3243	poly(R)-hydroxyalkanoic acid synthase
KSA16_006065	COG0786	glutamate:sodium symporter activity
KSA16_006075	COG2186	Transcriptional regulator
KSA16_006125	COG0477	Major facilitator Superfamily
KSA16_006205	COG0488	(ABC) transporter
KSA16_006210	COG3173	Aminoglycoside phosphotransferase
KSA16_006220	COG2433	Pfam Transposase IS66
KSA16_006260	COG1301	dicarboxylic acid transport
KSA16_006270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KSA16_006275	COG2011	ABC-type metal ion transport system permease component
KSA16_006280	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KSA16_006285	COG1464	Belongs to the NlpA lipoprotein family
KSA16_006290	COG0151	Belongs to the GarS family
KSA16_006295	COG0138	bifunctional purine biosynthesis protein purh
KSA16_006300	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KSA16_006330	COG2308	Evidence 4 Homologs of previously reported genes of
KSA16_006340	COG1305	Transglutaminase-like
KSA16_006350	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KSA16_006355	COG0305	Participates in initiation and elongation during chromosome replication
KSA16_006380	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KSA16_006390	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KSA16_006395	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KSA16_006420	COG1649	PFAM Uncharacterised BCR, COG1649
KSA16_006420	COG0726	polysaccharide deacetylase
KSA16_006425	COG1215	transferase activity, transferring glycosyl groups
KSA16_006430	COG3658	cytochrome
KSA16_006440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KSA16_006455	COG0583	DNA-binding transcription factor activity
KSA16_006475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KSA16_006480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KSA16_006495	COG1960	acyl-CoA dehydrogenase activity
KSA16_006500	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KSA16_006505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KSA16_006530	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KSA16_006535	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KSA16_006545	COG2205	protein histidine kinase activity
KSA16_006550	COG0745	RESPONSE REGULATOR receiver
KSA16_006555	COG0174	glutamine synthetase
KSA16_006575	COG0729	surface antigen
KSA16_006600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KSA16_006605	COG2814	Major facilitator Superfamily
KSA16_006620	COG0583	DNA-binding transcription factor activity
KSA16_006635	COG1187	pseudouridine synthase activity
KSA16_006655	COG0802	atpase or kinase
KSA16_006660	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KSA16_006670	COG1923	regulation of RNA biosynthetic process
KSA16_006675	COG0697	spore germination
KSA16_006690	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KSA16_006700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KSA16_006705	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KSA16_006705	COG0519	Catalyzes the synthesis of GMP from XMP
KSA16_006710	COG4302	ethanolamine ammonia-lyase activity
KSA16_006715	COG4303	Ethanolamine ammonia lyase large subunit
KSA16_006720	COG0531	amino acid
KSA16_006740	COG1454	alcohol dehydrogenase
KSA16_006745	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KSA16_006755	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
KSA16_006775	COG0308	aminopeptidase N
KSA16_006785	COG4221	oxidoreductase activity
KSA16_006795	COG1605	Chorismate mutase
KSA16_006815	COG1309	transcriptional regulator
KSA16_006825	COG0668	transmembrane transport
KSA16_006860	COG4773	Receptor
KSA16_006880	COG0488	(ABC) transporter
KSA16_006885	COG0589	response to stress
KSA16_006910	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KSA16_006920	COG3135	benzoate transporter
KSA16_006925	COG1522	sequence-specific DNA binding
KSA16_006935	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KSA16_006940	COG0583	DNA-binding transcription factor activity
KSA16_006950	COG0183	Belongs to the thiolase family
KSA16_006960	COG2030	dehydratase
KSA16_006965	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KSA16_006980	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KSA16_006990	COG0824	Thioesterase
KSA16_006995	COG1454	alcohol dehydrogenase
KSA16_007005	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KSA16_007025	COG0069	glutamate synthase activity
KSA16_007200	COG5410	chromosome segregation
KSA16_007320	COG0739	heme binding
KSA16_007415	COG2814	Major facilitator Superfamily
KSA16_007430	COG0511	ligase activity, forming carbon-carbon bonds
KSA16_007450	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KSA16_007450	COG1116	anion transmembrane transporter activity
KSA16_007455	COG0745	RESPONSE REGULATOR receiver
KSA16_007465	COG2146	nitrite reductase [NAD(P)H] activity
KSA16_007465	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KSA16_007470	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KSA16_007475	COG0243	molybdopterin cofactor binding
KSA16_007485	COG0243	molybdopterin cofactor binding
KSA16_007490	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KSA16_007505	COG0521	Mo-molybdopterin cofactor biosynthetic process
KSA16_007505	COG0315	cyclic pyranopterin monophosphate synthase activity
KSA16_007510	COG0303	'Molybdopterin
KSA16_007520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KSA16_007525	COG0697	spore germination
KSA16_007545	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KSA16_007550	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KSA16_007605	COG2204	response regulator
KSA16_007610	COG3852	Histidine kinase
KSA16_007630	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KSA16_007635	COG0575	Belongs to the CDS family
KSA16_007670	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KSA16_007685	COG2137	regulation of response to DNA damage stimulus
KSA16_007695	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KSA16_007700	COG1011	Hydrolase
KSA16_007725	COG1522	sequence-specific DNA binding
KSA16_007735	COG1113	amino acid transport
KSA16_007755	COG0659	secondary active sulfate transmembrane transporter activity
KSA16_007760	COG2135	peptidase activity
KSA16_007775	COG3300	MHYT domain
KSA16_007775	COG5001	Diguanylate cyclase
KSA16_007795	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KSA16_007795	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KSA16_007795	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KSA16_007800	COG1105	Belongs to the carbohydrate kinase PfkB family
KSA16_007805	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KSA16_007805	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KSA16_007835	COG0024	Methionine aminopeptidase
KSA16_007840	COG0583	DNA-binding transcription factor activity
KSA16_007850	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KSA16_007855	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KSA16_007860	COG0517	IMP dehydrogenase activity
KSA16_007860	COG0516	GMP reductase activity
KSA16_007885	COG0552	protein localization to endoplasmic reticulum
KSA16_007895	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
KSA16_007910	COG4890	Cyd operon protein YbgT
KSA16_007915	COG1294	oxidase, subunit
KSA16_007935	COG1585	Membrane protein implicated in regulation of membrane protease activity
KSA16_007945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KSA16_007950	COG4774	siderophore transport
KSA16_007965	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KSA16_007970	COG0569	domain protein
KSA16_007975	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KSA16_008005	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KSA16_008010	COG0542	response to heat
KSA16_008035	COG1902	pentaerythritol trinitrate reductase activity
KSA16_008035	COG0446	pyridine nucleotide-disulphide oxidoreductase
KSA16_008080	COG2323	membrane
KSA16_008085	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KSA16_008095	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KSA16_008100	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KSA16_008105	COG0183	Belongs to the thiolase family
KSA16_008110	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KSA16_008115	COG0596	Alpha beta hydrolase
KSA16_008120	COG2271	Major facilitator Superfamily
KSA16_008125	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KSA16_008130	COG3485	protocatechuate 3,4-dioxygenase
KSA16_008135	COG3485	protocatechuate 3,4-dioxygenase
KSA16_008140	COG0710	3-dehydroquinate dehydratase activity
KSA16_008145	COG3420	alginic acid biosynthetic process
KSA16_008150	COG3659	wide pore channel activity
KSA16_008155	COG4993	Dehydrogenase
KSA16_008165	COG2391	methyltransferase activity
KSA16_008180	COG1414	Transcriptional regulator
KSA16_008185	COG0583	DNA-binding transcription factor activity
KSA16_008190	COG1960	acyl-CoA dehydrogenase activity
KSA16_008215	COG2814	Major facilitator Superfamily
KSA16_008225	COG0154	amidase activity
KSA16_008245	COG4638	Rieske (2fe-2S)
KSA16_008255	COG1028	Short-chain dehydrogenase reductase Sdr
KSA16_008265	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KSA16_008275	COG3733	amine oxidase
KSA16_008285	COG1012	belongs to the aldehyde dehydrogenase family
KSA16_008295	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KSA16_008300	COG0183	Belongs to the thiolase family
KSA16_008305	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KSA16_008310	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KSA16_008320	COG4829	muconolactone delta-isomerase
KSA16_008325	COG4948	Mandelate Racemase Muconate Lactonizing
KSA16_008330	COG0583	DNA-binding transcription factor activity
KSA16_008340	COG2186	Transcriptional regulator
KSA16_008360	COG1012	belongs to the aldehyde dehydrogenase family
KSA16_008380	COG1960	acyl-CoA dehydrogenase activity
KSA16_008385	COG1028	Short-chain dehydrogenase reductase Sdr
KSA16_008390	COG3829	transcription factor binding
KSA16_008400	COG3162	membrane
KSA16_008415	COG1012	belongs to the aldehyde dehydrogenase family
KSA16_008430	COG0753	catalase activity
KSA16_008450	COG1846	Transcriptional regulator
KSA16_008455	COG1902	pentaerythritol trinitrate reductase activity
KSA16_008455	COG0446	pyridine nucleotide-disulphide oxidoreductase
KSA16_008465	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KSA16_008495	COG1309	transcriptional regulator
KSA16_008505	COG1335	isochorismatase
KSA16_008510	COG0583	DNA-binding transcription factor activity
KSA16_008520	COG0475	glutathione-regulated potassium exporter activity
KSA16_008520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KSA16_008530	COG1473	amidohydrolase
KSA16_008540	COG2831	hemolysin activation secretion protein
KSA16_008545	COG3210	domain, Protein
KSA16_008575	COG2188	Transcriptional regulator
KSA16_008590	COG0583	DNA-binding transcription factor activity
KSA16_008620	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KSA16_008650	COG1566	PFAM secretion protein HlyD family protein
KSA16_008665	COG1012	belongs to the aldehyde dehydrogenase family
KSA16_008670	COG0129	dihydroxy-acid dehydratase activity
KSA16_008680	COG0583	DNA-binding transcription factor activity
KSA16_008685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KSA16_008695	COG2084	Dehydrogenase
KSA16_008700	COG2207	Transcriptional regulator
KSA16_008715	COG1064	alcohol dehydrogenase
KSA16_008725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KSA16_008730	COG1120	ATPase activity
KSA16_008750	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KSA16_008870	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KSA16_008920	COG1028	Short-chain dehydrogenase reductase Sdr
KSA16_008935	COG2207	Transcriptional regulator
KSA16_008945	COG2205	protein histidine kinase activity
KSA16_008950	COG0745	RESPONSE REGULATOR receiver
KSA16_008955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KSA16_008960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KSA16_008965	COG1538	Outer membrane efflux protein
KSA16_009005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KSA16_009025	COG3539	Fimbrial protein
KSA16_009055	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KSA16_009065	COG0753	catalase activity
KSA16_009080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KSA16_009145	COG1535	isochorismatase
KSA16_009145	COG3433	isochorismatase activity
KSA16_009150	COG1028	Short-chain dehydrogenase reductase Sdr
KSA16_009155	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KSA16_009160	COG4149	molybdate abc transporter
KSA16_009165	COG0725	ABC transporter, periplasmic molybdate-binding protein
KSA16_009175	COG4638	Rieske (2fe-2S)
KSA16_009180	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KSA16_009185	COG0543	2 iron, 2 sulfur cluster binding
KSA16_009185	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KSA16_009210	COG1028	Short-chain dehydrogenase reductase Sdr
KSA16_009225	COG2207	Transcriptional regulator
KSA16_009235	COG1028	Short-chain dehydrogenase reductase Sdr
KSA16_009240	COG2610	gluconate transmembrane transporter activity
KSA16_009250	COG0583	DNA-binding transcription factor activity
KSA16_009260	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KSA16_009265	COG2031	fatty acid transporter
KSA16_009270	COG0183	Belongs to the thiolase family
KSA16_009275	COG0583	DNA-binding transcription factor activity
KSA16_009280	COG0583	DNA-binding transcription factor activity
KSA16_009295	COG1027	Aspartate ammonia-lyase
KSA16_009305	COG0477	Major facilitator Superfamily
KSA16_009325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KSA16_009330	COG4521	taurine ABC transporter
KSA16_009345	COG2188	Transcriptional regulator
KSA16_009355	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KSA16_009360	COG1733	regulation of RNA biosynthetic process
KSA16_009365	COG2207	Transcriptional regulator
KSA16_009365	COG3708	Transcriptional regulator
KSA16_009380	COG0730	response to heat
KSA16_009395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KSA16_009395	COG3453	Protein conserved in bacteria
KSA16_009405	COG3781	membrane
KSA16_009410	COG1063	alcohol dehydrogenase
KSA16_009420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KSA16_009425	COG0508	dehydrogenase complex catalyzes the overall conversion of
KSA16_009430	COG0022	dehydrogenase e1 component
KSA16_009435	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KSA16_009440	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KSA16_009455	COG3706	GGDEF domain
KSA16_009470	COG0133	tryptophan synthase activity
KSA16_009480	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KSA16_009515	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KSA16_009540	COG2226	methyltransferase
KSA16_009595	COG0842	Transport permease protein
KSA16_009600	COG0842	Transport permease protein
KSA16_009605	COG1131	(ABC) transporter
KSA16_009620	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KSA16_009625	COG4773	Receptor
KSA16_009640	COG3328	transposase activity
KSA16_009650	COG0730	response to heat
KSA16_009655	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KSA16_009675	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KSA16_009690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KSA16_009730	COG4264	IucA IucC family
KSA16_009735	COG4264	IucA IucC family
KSA16_009755	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KSA16_009770	COG1960	acyl-CoA dehydrogenase activity
KSA16_009775	COG1960	acyl-CoA dehydrogenase activity
KSA16_009780	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KSA16_009785	COG2207	Transcriptional regulator
KSA16_009790	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KSA16_009795	COG0776	regulation of translation
KSA16_009820	COG0822	iron-sulfur transferase activity
KSA16_009825	COG0316	Belongs to the HesB IscA family
KSA16_009855	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KSA16_009875	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KSA16_009880	COG0702	epimerase
KSA16_009915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KSA16_009925	COG0339	signal peptide processing
KSA16_009975	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KSA16_009980	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KSA16_010010	COG0776	regulation of translation
KSA16_010075	COG0084	hydrolase, TatD family'
KSA16_010095	COG1663	tetraacyldisaccharide 4'-kinase activity
KSA16_010100	COG1132	(ABC) transporter
KSA16_010110	COG0811	peptide transport
KSA16_010115	COG1475	DNA binding
KSA16_010120	COG1192	Involved in chromosome partitioning
KSA16_010130	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KSA16_010145	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KSA16_010150	COG0191	fructose-bisphosphate aldolase activity
KSA16_010170	COG0424	maF-like protein
KSA16_010175	COG2850	peptidyl-arginine hydroxylation
KSA16_010185	COG0640	Transcriptional regulator
KSA16_010195	COG3619	membrane
KSA16_010200	COG3122	Protein conserved in bacteria
KSA16_010205	COG1132	(ABC) transporter
KSA16_010225	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KSA16_010230	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KSA16_010240	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KSA16_010240	COG0506	proline dehydrogenase activity
KSA16_010240	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KSA16_010245	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KSA16_010260	COG3698	Phosphodiester glycosidase
KSA16_010270	COG2353	YceI-like domain
KSA16_010280	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KSA16_010325	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KSA16_010325	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KSA16_010350	COG3539	Fimbrial protein
KSA16_010355	COG3121	Chaperone
KSA16_010380	COG0697	spore germination
KSA16_010390	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KSA16_010400	COG0583	DNA-binding transcription factor activity
KSA16_010420	COG1309	transcriptional regulator
KSA16_010435	COG1522	sequence-specific DNA binding
KSA16_010445	COG1126	abc transporter atp-binding protein
KSA16_010450	COG0765	amino acid transport
KSA16_010455	COG0765	amino acid transport
KSA16_010485	COG1464	Belongs to the NlpA lipoprotein family
KSA16_010495	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KSA16_010500	COG2011	ABC-type metal ion transport system permease component
KSA16_010505	COG0012	GTP binding
KSA16_010530	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KSA16_010570	COG0386	Belongs to the glutathione peroxidase family
KSA16_010580	COG0436	Aminotransferase
KSA16_010620	COG3634	alkyl hydroperoxide reductase activity
KSA16_010635	COG0583	DNA-binding transcription factor activity
KSA16_010640	COG0798	PFAM Bile acid sodium symporter
KSA16_010645	COG0640	Transcriptional regulator
KSA16_010660	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KSA16_010670	COG0583	DNA-binding transcription factor activity
KSA16_010680	COG1953	Uracil, thiamine, allantoin
KSA16_010690	COG2175	clavaminate synthase activity
KSA16_010695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KSA16_010700	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KSA16_010705	COG4521	taurine ABC transporter
KSA16_010715	COG0477	Major facilitator Superfamily
KSA16_010735	COG1271	oxidase subunit
KSA16_010740	COG1294	oxidase, subunit
KSA16_010750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KSA16_010770	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KSA16_010790	COG3052	prosthetic group binding
KSA16_010795	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
KSA16_010805	COG2814	Major facilitator Superfamily
KSA16_010825	COG1346	cytolysis
KSA16_010835	COG0583	DNA-binding transcription factor activity
KSA16_010840	COG0625	glutathione transferase activity
KSA16_010845	COG0625	glutathione transferase activity
KSA16_010850	COG0583	DNA-binding transcription factor activity
KSA16_010865	COG1045	serine acetyltransferase
KSA16_010870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KSA16_010875	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KSA16_010885	COG1280	lysine exporter protein (LysE YggA)
KSA16_010900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KSA16_010905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KSA16_010910	COG1126	abc transporter atp-binding protein
KSA16_010915	COG0765	amino acid transport
KSA16_010920	COG0765	amino acid transport
KSA16_010940	COG0784	Response regulator, receiver
KSA16_010940	COG2205	protein histidine kinase activity
KSA16_010960	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KSA16_010980	COG1028	Short-chain dehydrogenase reductase Sdr
KSA16_011030	COG0583	DNA-binding transcription factor activity
KSA16_011060	COG0318	PFAM AMP-dependent synthetase and ligase
KSA16_011065	COG1309	transcriptional regulator
KSA16_011070	COG1960	acyl-CoA dehydrogenase activity
KSA16_011075	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KSA16_011080	COG1024	Enoyl-CoA hydratase
KSA16_011085	COG4770	biotin carboxylase activity
KSA16_011095	COG0583	DNA-binding transcription factor activity
KSA16_011110	COG1960	acyl-CoA dehydrogenase activity
KSA16_011120	COG2814	Major facilitator Superfamily
KSA16_011130	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KSA16_011135	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KSA16_011140	COG2814	Major facilitator Superfamily
KSA16_011145	COG1960	acyl-CoA dehydrogenase activity
KSA16_011150	COG1024	Enoyl-CoA hydratase
KSA16_011155	COG1028	Short-chain dehydrogenase reductase Sdr
KSA16_011160	COG1250	3-hydroxyacyl-CoA dehydrogenase
KSA16_011165	COG0183	Belongs to the thiolase family
KSA16_011175	COG2814	Major facilitator Superfamily
KSA16_011185	COG1024	Enoyl-CoA hydratase
KSA16_011205	COG1960	acyl-CoA dehydrogenase activity
KSA16_011210	COG2814	Major facilitator Superfamily
KSA16_011215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KSA16_011220	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KSA16_011235	COG3842	ATPase activity
KSA16_011240	COG1840	ABC-type Fe3 transport system, periplasmic component
KSA16_011250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KSA16_011255	COG1414	Transcriptional regulator
KSA16_011265	COG0583	DNA-binding transcription factor activity
KSA16_011270	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KSA16_011275	COG1012	belongs to the aldehyde dehydrogenase family
KSA16_011285	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KSA16_011295	COG1012	belongs to the aldehyde dehydrogenase family
KSA16_011300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KSA16_011305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KSA16_011310	COG2267	carboxylic ester hydrolase activity
KSA16_011330	COG3038	cytochrome b561
KSA16_011335	COG0753	catalase activity
KSA16_011370	COG2050	protein possibly involved in aromatic compounds catabolism
KSA16_011380	COG3327	negative regulation of DNA-templated transcription, initiation
KSA16_011385	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
KSA16_011390	COG0183	Belongs to the thiolase family
KSA16_011395	COG1250	3-hydroxyacyl-CoA dehydrogenase
KSA16_011400	COG1024	Enoyl-CoA hydratase
KSA16_011405	COG1024	Enoyl-CoA hydratase
KSA16_011410	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KSA16_011415	COG2151	metal-sulfur cluster biosynthetic enzyme
KSA16_011420	COG3396	Phenylacetate-CoA oxygenase
KSA16_011425	COG3460	Phenylacetate-CoA oxygenase
KSA16_011430	COG3396	Phenylacetate-CoA oxygenase
KSA16_011435	COG2030	dehydratase
KSA16_011435	COG1012	belongs to the aldehyde dehydrogenase family
KSA16_011440	COG1760	l-serine dehydratase
KSA16_011445	COG0531	amino acid
KSA16_011450	COG1012	belongs to the aldehyde dehydrogenase family
KSA16_011465	COG0446	pyridine nucleotide-disulphide oxidoreductase
KSA16_011475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KSA16_011495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KSA16_011505	COG0789	Transcriptional regulator
KSA16_011520	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KSA16_011535	COG2807	transmembrane transport
KSA16_011540	COG0590	tRNA wobble adenosine to inosine editing
KSA16_011660	COG1116	anion transmembrane transporter activity
KSA16_011665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KSA16_011675	COG0864	Transcriptional regulator
KSA16_011695	COG2249	NAD(P)H dehydrogenase (quinone) activity
KSA16_011700	COG0439	Biotin carboxylase
KSA16_011715	COG1063	alcohol dehydrogenase
KSA16_011725	COG1309	transcriptional regulator
KSA16_011745	COG0038	chloride channel
KSA16_011750	COG4770	biotin carboxylase activity
KSA16_011770	COG1914	H( )-stimulated, divalent metal cation uptake system
KSA16_011775	COG0583	DNA-binding transcription factor activity
KSA16_011825	COG1250	3-hydroxyacyl-CoA dehydrogenase
KSA16_011845	COG2814	Major facilitator Superfamily
KSA16_011860	COG1560	Kdo2-lipid A biosynthetic process
KSA16_011870	COG5006	permease, DMT superfamily
KSA16_011875	COG1522	sequence-specific DNA binding
KSA16_011890	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KSA16_011900	COG4122	O-methyltransferase activity
KSA16_011930	COG1538	Outer membrane efflux protein
KSA16_011935	COG1137	ATPase activity
KSA16_011940	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KSA16_011950	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KSA16_011955	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KSA16_011955	COG0517	IMP dehydrogenase activity
KSA16_011990	COG2814	Major facilitator Superfamily
KSA16_012025	COG1278	Cold shock
KSA16_012030	COG1280	lysine exporter protein (LysE YggA)
KSA16_012060	COG1570	exodeoxyribonuclease VII activity
KSA16_012110	COG0583	DNA-binding transcription factor activity
KSA16_012120	COG4638	Rieske (2fe-2S)
KSA16_012125	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KSA16_012130	COG0543	2 iron, 2 sulfur cluster binding
KSA16_012130	COG0633	Ferredoxin
KSA16_012135	COG1028	Short-chain dehydrogenase reductase Sdr
KSA16_012140	COG3135	benzoate transporter
KSA16_012145	COG2814	Major facilitator Superfamily
KSA16_012160	COG1643	Atp-dependent helicase
KSA16_012165	COG0450	alkyl hydroperoxide reductase
KSA16_012175	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KSA16_012185	COG3634	alkyl hydroperoxide reductase activity
KSA16_012205	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KSA16_012210	COG0625	glutathione transferase activity
KSA16_012220	COG2885	chlorophyll binding
KSA16_012255	COG0542	response to heat
KSA16_012270	COG1765	OsmC-like protein
KSA16_012290	COG0667	Aldo Keto reductase
KSA16_012305	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KSA16_012315	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KSA16_012325	COG0527	aspartate kinase activity
KSA16_012340	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KSA16_012450	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KSA16_012500	COG1012	belongs to the aldehyde dehydrogenase family
KSA16_012520	COG0531	amino acid
KSA16_012530	COG1113	amino acid transport
KSA16_012570	COG3209	COG3209 Rhs family protein
KSA16_012600	COG4269	membrane
KSA16_012615	COG0446	pyridine nucleotide-disulphide oxidoreductase
KSA16_012615	COG1902	pentaerythritol trinitrate reductase activity
KSA16_012625	COG3706	GGDEF domain
KSA16_012625	COG4251	negative regulation of phosphorylation
KSA16_012625	COG5001	Diguanylate cyclase
KSA16_012625	COG2203	Gaf domain
KSA16_012635	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KSA16_012655	COG4172	Belongs to the ABC transporter superfamily
KSA16_012660	COG4239	(ABC) transporter, permease
KSA16_012665	COG4174	ABC transporter (Permease)
KSA16_012675	COG1388	LysM domain
KSA16_012675	COG0741	lytic transglycosylase activity
KSA16_012675	COG0741	lytic transglycosylase activity
KSA16_012675	COG1388	LysM domain
KSA16_012680	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KSA16_012720	COG0583	DNA-binding transcription factor activity
KSA16_012725	COG1279	arginine transmembrane transporter activity
KSA16_012745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KSA16_012750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KSA16_012755	COG0006	proline dipeptidase activity
KSA16_012795	COG2194	sulfuric ester hydrolase activity
KSA16_012840	COG0739	heme binding
KSA16_013165	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KSA16_013190	COG3384	dioxygenase
KSA16_013200	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KSA16_013205	COG2878	Part of a membrane complex involved in electron transport
KSA16_013210	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KSA16_013235	COG0768	penicillin binding
KSA16_013240	COG0742	ribosomal rna small subunit methyltransferase
KSA16_013255	COG0830	nickel cation binding
KSA16_013265	COG0804	urea catabolic process
KSA16_013305	COG1253	flavin adenine dinucleotide binding
KSA16_013310	COG2851	Citrate transporter
KSA16_013360	COG1773	rubredoxin
KSA16_013365	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KSA16_013375	COG0583	DNA-binding transcription factor activity
KSA16_013400	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KSA16_013405	COG4181	ATPase activity
KSA16_013450	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KSA16_013470	COG0306	phosphate transporter
KSA16_013480	COG3958	Transketolase
KSA16_013485	COG3959	Transketolase, thiamine diphosphate binding domain
KSA16_013490	COG2271	Major facilitator Superfamily
KSA16_013495	COG1028	Short-chain dehydrogenase reductase Sdr
KSA16_013500	COG0583	DNA-binding transcription factor activity
KSA16_013515	COG2223	nitrite transmembrane transporter activity
KSA16_013520	COG2207	Transcriptional regulator
KSA16_013525	COG2066	Belongs to the glutaminase family
KSA16_013530	COG0242	peptide deformylase activity
KSA16_013535	COG0477	Major facilitator Superfamily
KSA16_013545	COG0028	Belongs to the TPP enzyme family
KSA16_013560	COG1028	Short-chain dehydrogenase reductase Sdr
KSA16_013565	COG2267	carboxylic ester hydrolase activity
KSA16_013575	COG2271	Major facilitator Superfamily
KSA16_013580	COG0446	pyridine nucleotide-disulphide oxidoreductase
KSA16_013590	COG1028	Short-chain dehydrogenase reductase Sdr
KSA16_013610	COG1414	Transcriptional regulator
KSA16_013625	COG1024	Enoyl-CoA hydratase
KSA16_013635	COG1215	transferase activity, transferring glycosyl groups
KSA16_013640	COG0726	polysaccharide deacetylase
KSA16_013640	COG1649	PFAM Uncharacterised BCR, COG1649
KSA16_013650	COG4681	YaeQ
KSA16_013660	COG0523	cobalamin synthesis protein
KSA16_013675	COG1607	acyl-coa hydrolase
KSA16_013685	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KSA16_013690	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KSA16_013695	COG1309	transcriptional regulator
KSA16_013720	COG2040	homocysteine
KSA16_013725	COG0531	amino acid
KSA16_013750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KSA16_013755	COG0477	Major facilitator Superfamily
KSA16_013815	COG1061	Type III restriction enzyme res subunit
KSA16_013825	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KSA16_013830	COG1192	Involved in chromosome partitioning
KSA16_013840	COG1061	Type III restriction enzyme res subunit
KSA16_013930	COG0592	DNA-directed DNA polymerase activity
KSA16_013970	COG2026	Addiction module toxin, RelE StbE family
KSA16_014120	COG3755	Protein conserved in bacteria
KSA16_014165	COG1484	DNA-dependent DNA replication
KSA16_014255	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KSA16_014325	COG0405	Gamma-glutamyltransferase
KSA16_014330	COG2814	Major facilitator Superfamily
KSA16_014340	COG2050	protein possibly involved in aromatic compounds catabolism
KSA16_014355	COG1090	epimerase
KSA16_014375	COG0420	3'-5' exonuclease activity
KSA16_014400	COG0735	belongs to the Fur family
KSA16_014405	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KSA16_014425	COG0121	glutamine amidotransferase
KSA16_014440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KSA16_014450	COG0210	DNA helicase
KSA16_014455	COG2885	chlorophyll binding
KSA16_014460	COG0204	Acyl-transferase
KSA16_014475	COG2894	cell division
KSA16_014495	COG1280	lysine exporter protein (LysE YggA)
KSA16_014500	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KSA16_014500	COG1674	ftsk spoiiie
KSA16_014505	COG0492	ferredoxin-NADP+ reductase activity
KSA16_014510	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KSA16_014520	COG0456	acetyltransferase
KSA16_014565	COG1981	membrane
KSA16_014580	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KSA16_014580	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KSA16_014600	COG1012	belongs to the aldehyde dehydrogenase family
KSA16_014610	COG0657	acetylesterase activity
KSA16_014620	COG0473	3-isopropylmalate dehydrogenase activity
KSA16_014625	COG0583	DNA-binding transcription factor activity
KSA16_014645	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KSA16_014670	COG0564	pseudouridine synthase activity
KSA16_014680	COG0358	DNA primase activity
KSA16_014695	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KSA16_014725	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KSA16_014755	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KSA16_014765	COG0351	phosphomethylpyrimidine kinase
KSA16_014765	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KSA16_014765	COG0352	thiamine-phosphate diphosphorylase activity
KSA16_014770	COG1652	LysM domain
KSA16_014795	COG1399	metal-binding, possibly nucleic acid-binding protein
KSA16_014800	COG3101	peptidyl-lysine hydroxylation
KSA16_014805	COG0009	L-threonylcarbamoyladenylate synthase
KSA16_014810	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KSA16_014815	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KSA16_014830	COG4106	trans-aconitate 2-methyltransferase activity
KSA16_014845	COG0596	Alpha beta hydrolase
KSA16_014845	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KSA16_014845	COG2226	methyltransferase
KSA16_014850	COG1877	trehalose-phosphatase activity
KSA16_014855	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
KSA16_014860	COG2223	nitrite transmembrane transporter activity
KSA16_014880	COG1196	nuclear chromosome segregation
KSA16_014890	COG0730	response to heat
KSA16_014905	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KSA16_014915	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KSA16_014975	COG0489	protein tyrosine kinase activity
KSA16_014985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KSA16_014985	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KSA16_015015	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KSA16_015020	COG2081	HI0933 family
KSA16_015030	COG0668	transmembrane transport
KSA16_015050	COG0583	DNA-binding transcription factor activity
KSA16_015070	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KSA16_015075	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KSA16_015105	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KSA16_015145	COG0745	RESPONSE REGULATOR receiver
KSA16_015165	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KSA16_015175	COG2205	protein histidine kinase activity
KSA16_015245	COG4993	Dehydrogenase
KSA16_015270	COG0384	phenazine biosynthesis protein PhzF
KSA16_015295	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KSA16_015310	COG0583	DNA-binding transcription factor activity
KSA16_015340	COG0583	DNA-binding transcription factor activity
KSA16_015355	COG0583	DNA-binding transcription factor activity
KSA16_015360	COG1053	succinate dehydrogenase
KSA16_015370	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KSA16_015375	COG2814	Major facilitator Superfamily
KSA16_015380	COG1960	acyl-CoA dehydrogenase activity
KSA16_015385	COG0583	DNA-binding transcription factor activity
KSA16_015390	COG1063	alcohol dehydrogenase
KSA16_015420	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KSA16_015425	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KSA16_015430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KSA16_015445	COG3667	copper resistance
KSA16_015450	COG2132	Multicopper oxidase
KSA16_015460	COG0561	phosphatase activity
KSA16_015465	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KSA16_015490	COG1214	PFAM Peptidase M22, glycoprotease
KSA16_015540	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KSA16_015550	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KSA16_015555	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KSA16_015560	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KSA16_015620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KSA16_015630	COG1846	Transcriptional regulator
KSA16_015635	COG1764	response to oxidative stress
KSA16_015675	COG0037	tRNA processing
KSA16_015685	COG0248	Ppx GppA phosphatase
KSA16_015715	COG0072	phenylalanine-tRNA ligase activity
KSA16_015760	COG1238	metal cluster binding
KSA16_015765	COG0625	glutathione transferase activity
KSA16_015780	COG0318	PFAM AMP-dependent synthetase and ligase
KSA16_015785	COG3028	Belongs to the UPF0307 family
KSA16_015790	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KSA16_015810	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KSA16_015815	COG0617	tRNA 3'-terminal CCA addition
KSA16_015820	COG1555	photosystem II stabilization
KSA16_015825	COG3956	TIGRFAM MazG family protein
KSA16_015835	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KSA16_015855	COG5002	protein histidine kinase activity
KSA16_015855	COG2205	protein histidine kinase activity
KSA16_015855	COG0784	Response regulator, receiver
KSA16_015860	COG1024	Enoyl-CoA hydratase
KSA16_015865	COG2084	Dehydrogenase
KSA16_015870	COG3622	Belongs to the hyi family
KSA16_015900	COG0697	spore germination
KSA16_015910	COG2814	Major facilitator Superfamily
KSA16_015915	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KSA16_015925	COG0583	DNA-binding transcription factor activity
KSA16_015935	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KSA16_015950	COG0084	hydrolase, TatD family'
KSA16_015965	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KSA16_015995	COG0440	acetolactate synthase activity
KSA16_016000	COG0028	Belongs to the TPP enzyme family
KSA16_016025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KSA16_016030	COG1136	(ABC) transporter
KSA16_016030	COG0577	efflux transmembrane transporter activity
KSA16_016035	COG1538	Outer membrane efflux protein
KSA16_016050	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KSA16_016055	COG1162	GTPase activity
KSA16_016065	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KSA16_016085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KSA16_016090	COG1028	Short-chain dehydrogenase reductase Sdr
KSA16_016130	COG2986	histidine ammonia-lyase
KSA16_016145	COG0318	PFAM AMP-dependent synthetase and ligase
KSA16_016155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KSA16_016200	COG1426	Protein conserved in bacteria
KSA16_016235	COG0793	Belongs to the peptidase S41A family
KSA16_016250	COG2267	carboxylic ester hydrolase activity
KSA16_016260	COG1012	belongs to the aldehyde dehydrogenase family
KSA16_016265	COG3265	gluconokinase activity
KSA16_016275	COG0800	Aldolase
KSA16_016285	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KSA16_016290	COG0280	phosphate acetyltransferase
KSA16_016290	COG0857	belongs to the CobB CobQ family
KSA16_016295	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KSA16_016295	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KSA16_016315	COG0740	serine-type endopeptidase activity
KSA16_016325	COG4774	siderophore transport
KSA16_016335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KSA16_016345	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KSA16_016345	COG2813	Specifically methylates the guanine in position
KSA16_016445	COG0788	formyltetrahydrofolate deformylase activity
KSA16_016470	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KSA16_016470	COG4651	solute:proton antiporter activity
KSA16_016490	COG0724	RNA recognition motif
KSA16_016495	COG0210	DNA helicase
KSA16_016520	COG1733	regulation of RNA biosynthetic process
KSA16_016530	COG2900	Belongs to the SlyX family
KSA16_016535	COG0488	(ABC) transporter
KSA16_016540	COG1280	lysine exporter protein (LysE YggA)
KSA16_016545	COG1560	Kdo2-lipid A biosynthetic process
KSA16_016555	COG1301	dicarboxylic acid transport
KSA16_016610	COG0473	3-isopropylmalate dehydrogenase activity
KSA16_016675	COG0583	DNA-binding transcription factor activity
KSA16_016685	COG0625	glutathione transferase activity
KSA16_016690	COG2378	regulation of single-species biofilm formation
KSA16_016695	COG0546	phosphoglycolate phosphatase activity
KSA16_016705	COG1530	ribonuclease E activity
KSA16_016710	COG0318	PFAM AMP-dependent synthetase and ligase
KSA16_016725	COG0583	DNA-binding transcription factor activity
KSA16_016730	COG4221	oxidoreductase activity
KSA16_016735	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KSA16_016745	COG0534	Mate efflux family protein
KSA16_016760	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KSA16_016800	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KSA16_016805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KSA16_016820	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KSA16_016830	COG0644	oxidoreductase
KSA16_016830	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
KSA16_016835	COG0425	Belongs to the sulfur carrier protein TusA family
KSA16_016840	COG4535	Mg2 and Co2 transporter CorC
KSA16_016850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KSA16_016870	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KSA16_016875	COG0475	glutathione-regulated potassium exporter activity
KSA16_016875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KSA16_016880	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KSA16_016890	COG0484	heat shock protein binding
KSA16_016895	COG0789	Transcriptional regulator
KSA16_016900	COG0598	Magnesium transport protein CorA
KSA16_016915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KSA16_016920	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KSA16_016925	COG1074	ATP-dependent DNA helicase activity
KSA16_016930	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KSA16_016950	COG2226	methyltransferase
KSA16_016965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KSA16_016970	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KSA16_016985	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KSA16_016985	COG2111	Na H antiporter
KSA16_016990	COG1006	Multisubunit Na H antiporter MnhC subunit
KSA16_016995	COG0651	ATP synthesis coupled electron transport
KSA16_017000	COG1863	multisubunit Na H antiporter MnhE subunit
KSA16_017005	COG2212	antiporter activity
KSA16_017010	COG1320	monovalent cation:proton antiporter activity
KSA16_017025	COG0195	Participates in both transcription termination and antitermination
KSA16_017075	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KSA16_017080	COG0237	dephospho-CoA kinase activity
KSA16_017090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KSA16_017105	COG0497	DNA recombination
KSA16_017115	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KSA16_017145	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KSA16_017145	COG2169	Transcriptional regulator
KSA16_017150	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KSA16_017215	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KSA16_017230	COG0326	Molecular chaperone. Has ATPase activity
KSA16_017245	COG2056	Na+-H+ antiporter family
KSA16_017250	COG0596	Alpha beta hydrolase
KSA16_017345	COG0546	phosphoglycolate phosphatase activity
KSA16_017350	COG1716	ATPase activity
KSA16_017395	COG0181	hydroxymethylbilane synthase activity
KSA16_017405	COG3275	phosphorelay sensor kinase activity
KSA16_017425	COG1538	Outer membrane efflux protein
KSA16_017430	COG0697	spore germination
KSA16_017455	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KSA16_017460	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KSA16_017465	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KSA16_017470	COG0772	Belongs to the SEDS family
KSA16_017495	COG4974	Belongs to the 'phage' integrase family
KSA16_017500	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KSA16_017510	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KSA16_017520	COG2197	response regulator
KSA16_017535	COG0793	Belongs to the peptidase S41A family
KSA16_017540	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KSA16_017545	COG0795	lipopolysaccharide-transporting ATPase activity
KSA16_017585	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KSA16_017585	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KSA16_017595	COG0004	ammonium transporteR
KSA16_017600	COG0347	Belongs to the P(II) protein family
KSA16_017610	COG0606	chelatase, subunit chli
KSA16_017620	COG0235	Class ii aldolase
KSA16_017625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KSA16_017645	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KSA16_017660	COG0318	PFAM AMP-dependent synthetase and ligase
KSA16_017670	COG0477	Major facilitator Superfamily
KSA16_017675	COG2860	membrane
KSA16_017680	COG3012	SEC-C Motif Domain Protein
KSA16_017685	COG1253	flavin adenine dinucleotide binding
KSA16_017695	COG2814	Major facilitator Superfamily
KSA16_017705	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KSA16_017745	COG0655	NAD(P)H dehydrogenase (quinone) activity
KSA16_017755	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KSA16_017825	COG0758	DNA mediated transformation
KSA16_017835	COG0697	spore germination
KSA16_017840	COG1309	transcriptional regulator
KSA16_017855	COG0386	Belongs to the glutathione peroxidase family
KSA16_017925	COG1121	(ABC) transporter
KSA16_017930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KSA16_017935	COG1280	lysine exporter protein (LysE YggA)
KSA16_017940	COG2837	iron assimilation
KSA16_017950	COG0281	malic enzyme
KSA16_017995	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KSA16_017995	COG0519	Catalyzes the synthesis of GMP from XMP
KSA16_018000	COG4399	Belongs to the UPF0754 family
KSA16_018010	COG0586	Pfam SNARE associated Golgi protein
KSA16_018025	COG1192	Involved in chromosome partitioning
KSA16_018035	COG0271	Belongs to the BolA IbaG family
KSA16_018055	COG1024	Enoyl-CoA hydratase
KSA16_018060	COG1024	Enoyl-CoA hydratase
KSA16_018065	COG1960	acyl-CoA dehydrogenase activity
KSA16_018070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KSA16_018090	COG1113	amino acid transport
KSA16_018095	COG1113	amino acid transport
KSA16_018100	COG0251	oxidation-reduction process
KSA16_018140	COG0564	pseudouridine synthase activity
KSA16_018205	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KSA16_018220	COG1802	Transcriptional regulator
KSA16_018230	COG1448	Aminotransferase
KSA16_018235	COG0277	FAD linked oxidase domain protein
KSA16_018245	COG2186	Transcriptional regulator
KSA16_018255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KSA16_018270	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KSA16_018285	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KSA16_018290	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KSA16_018295	COG1216	Glycosyl transferase, family 2
KSA16_018305	COG3562	capsule polysaccharide
KSA16_018315	COG2089	acid synthase
KSA16_018330	COG1083	cytidylyl-transferase
KSA16_018335	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KSA16_018340	COG1086	Polysaccharide biosynthesis protein
KSA16_018345	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KSA16_018375	COG0728	peptidoglycan biosynthetic process
KSA16_018380	COG3023	N-Acetylmuramoyl-L-alanine amidase
KSA16_018435	COG0546	phosphoglycolate phosphatase activity
KSA16_018440	COG1028	Short-chain dehydrogenase reductase Sdr
KSA16_018460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KSA16_018465	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KSA16_018470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KSA16_018475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KSA16_018480	COG1116	anion transmembrane transporter activity
KSA16_018485	COG1309	transcriptional regulator
KSA16_018490	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KSA16_018500	COG0196	riboflavin kinase activity
KSA16_018505	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KSA16_018515	COG1047	Peptidyl-prolyl cis-trans
KSA16_018555	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KSA16_018560	COG0657	acetylesterase activity
KSA16_018580	COG0583	DNA-binding transcription factor activity
KSA16_018610	COG2951	lytic endotransglycosylase activity
KSA16_018615	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KSA16_018630	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KSA16_018640	COG0671	phosphoesterase, PA-phosphatase related
KSA16_018645	COG0861	Integral membrane protein TerC family
KSA16_018655	COG0754	glutathionylspermidine amidase activity
KSA16_018665	COG0402	S-adenosylhomocysteine deaminase activity
KSA16_018680	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KSA16_018685	COG1230	cation diffusion facilitator family transporter
KSA16_018700	COG0706	membrane insertase activity
KSA16_018725	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KSA16_018725	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KSA16_018740	COG0587	DNA-directed DNA polymerase activity
KSA16_018785	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KSA16_018840	COG0358	DNA primase activity
KSA16_019020	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KSA16_019040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KSA16_019120	COG1063	alcohol dehydrogenase
KSA16_019145	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
KSA16_019160	COG1979	alcohol dehydrogenase
KSA16_019170	COG1902	pentaerythritol trinitrate reductase activity
KSA16_019180	COG1309	transcriptional regulator
KSA16_019225	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KSA16_019265	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KSA16_019270	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KSA16_019270	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes