locus-tag	class	description
IMO23_00010	COG0592	DNA-directed DNA polymerase activity
IMO23_00020	COG0187	DNA topoisomerase II activity
IMO23_00030	COG0586	Pfam SNARE associated Golgi protein
IMO23_00035	COG0488	(ABC) transporter
IMO23_00060	COG0596	Alpha beta hydrolase
IMO23_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IMO23_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IMO23_00110	COG1047	Peptidyl-prolyl cis-trans
IMO23_00120	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IMO23_00125	COG0196	riboflavin kinase activity
IMO23_00135	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IMO23_00140	COG1309	transcriptional regulator
IMO23_00145	COG1116	anion transmembrane transporter activity
IMO23_00150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IMO23_00155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMO23_00160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IMO23_00165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IMO23_00185	COG1028	Short-chain dehydrogenase reductase Sdr
IMO23_00190	COG0546	phosphoglycolate phosphatase activity
IMO23_00240	COG3023	N-Acetylmuramoyl-L-alanine amidase
IMO23_00245	COG0728	peptidoglycan biosynthetic process
IMO23_00275	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IMO23_00280	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IMO23_00285	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IMO23_00330	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IMO23_00340	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IMO23_00350	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IMO23_00365	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IMO23_00370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMO23_00380	COG2186	Transcriptional regulator
IMO23_00390	COG0277	FAD linked oxidase domain protein
IMO23_00395	COG1448	Aminotransferase
IMO23_00405	COG1802	Transcriptional regulator
IMO23_00420	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IMO23_00470	COG0564	pseudouridine synthase activity
IMO23_00510	COG0251	oxidation-reduction process
IMO23_00515	COG1113	amino acid transport
IMO23_00520	COG1113	amino acid transport
IMO23_00540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IMO23_00545	COG1960	acyl-CoA dehydrogenase activity
IMO23_00550	COG1024	Enoyl-CoA hydratase
IMO23_00555	COG1024	Enoyl-CoA hydratase
IMO23_00560	COG0477	Major facilitator Superfamily
IMO23_00565	COG3916	Acyl-homoserine-lactone synthase
IMO23_00590	COG0271	Belongs to the BolA IbaG family
IMO23_00600	COG1192	Involved in chromosome partitioning
IMO23_00615	COG0586	Pfam SNARE associated Golgi protein
IMO23_00620	COG2259	Doxx family
IMO23_00630	COG0519	Catalyzes the synthesis of GMP from XMP
IMO23_00630	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IMO23_00675	COG0281	malic enzyme
IMO23_00680	COG2837	iron assimilation
IMO23_00685	COG1280	lysine exporter protein (LysE YggA)
IMO23_00690	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IMO23_00695	COG1121	(ABC) transporter
IMO23_00770	COG0697	spore germination
IMO23_00780	COG0758	DNA mediated transformation
IMO23_00815	COG1309	transcriptional regulator
IMO23_00850	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IMO23_00860	COG0655	NAD(P)H dehydrogenase (quinone) activity
IMO23_00895	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IMO23_00905	COG0477	Major facilitator Superfamily
IMO23_00915	COG1253	flavin adenine dinucleotide binding
IMO23_00920	COG3012	SEC-C Motif Domain Protein
IMO23_00925	COG2860	membrane
IMO23_00930	COG0477	Major facilitator Superfamily
IMO23_00940	COG0318	PFAM AMP-dependent synthetase and ligase
IMO23_00955	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IMO23_00970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IMO23_00990	COG0347	Belongs to the P(II) protein family
IMO23_00995	COG0004	ammonium transporteR
IMO23_01005	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IMO23_01005	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IMO23_01050	COG0795	lipopolysaccharide-transporting ATPase activity
IMO23_01055	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IMO23_01060	COG0793	Belongs to the peptidase S41A family
IMO23_01075	COG2197	response regulator
IMO23_01085	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IMO23_01095	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IMO23_01100	COG4974	Belongs to the 'phage' integrase family
IMO23_01125	COG0772	Belongs to the SEDS family
IMO23_01130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IMO23_01135	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IMO23_01140	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IMO23_01165	COG0697	spore germination
IMO23_01170	COG1538	Outer membrane efflux protein
IMO23_01210	COG0181	hydroxymethylbilane synthase activity
IMO23_01255	COG1716	ATPase activity
IMO23_01260	COG0546	phosphoglycolate phosphatase activity
IMO23_01355	COG0596	Alpha beta hydrolase
IMO23_01360	COG2056	Na+-H+ antiporter family
IMO23_01375	COG0326	Molecular chaperone. Has ATPase activity
IMO23_01390	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IMO23_01450	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IMO23_01455	COG2169	Transcriptional regulator
IMO23_01455	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IMO23_01485	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IMO23_01495	COG0497	DNA recombination
IMO23_01510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMO23_01520	COG0237	dephospho-CoA kinase activity
IMO23_01570	COG0195	Participates in both transcription termination and antitermination
IMO23_01585	COG1320	monovalent cation:proton antiporter activity
IMO23_01590	COG2212	antiporter activity
IMO23_01595	COG1863	multisubunit Na H antiporter MnhE subunit
IMO23_01600	COG0651	ATP synthesis coupled electron transport
IMO23_01605	COG1006	Multisubunit Na H antiporter MnhC subunit
IMO23_01610	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IMO23_01610	COG2111	Na H antiporter
IMO23_01625	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IMO23_01645	COG2226	methyltransferase
IMO23_01665	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IMO23_01670	COG1074	ATP-dependent DNA helicase activity
IMO23_01675	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IMO23_01680	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IMO23_01695	COG0598	Magnesium transport protein CorA
IMO23_01700	COG0789	Transcriptional regulator
IMO23_01705	COG0484	heat shock protein binding
IMO23_01720	COG0475	glutathione-regulated potassium exporter activity
IMO23_01720	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IMO23_01725	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IMO23_01745	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMO23_01755	COG4535	Mg2 and Co2 transporter CorC
IMO23_01760	COG0425	Belongs to the sulfur carrier protein TusA family
IMO23_01765	COG0644	oxidoreductase
IMO23_01765	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IMO23_01775	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IMO23_01790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IMO23_01795	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IMO23_01805	COG0493	'glutamate synthase
IMO23_01805	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IMO23_01835	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IMO23_01850	COG0534	Mate efflux family protein
IMO23_01860	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IMO23_01865	COG4221	oxidoreductase activity
IMO23_01870	COG0583	DNA-binding transcription factor activity
IMO23_01885	COG0318	PFAM AMP-dependent synthetase and ligase
IMO23_01890	COG1530	ribonuclease E activity
IMO23_01900	COG0546	phosphoglycolate phosphatase activity
IMO23_01905	COG2378	regulation of single-species biofilm formation
IMO23_01910	COG0625	glutathione transferase activity
IMO23_01920	COG0583	DNA-binding transcription factor activity
IMO23_01980	COG0473	3-isopropylmalate dehydrogenase activity
IMO23_02035	COG1301	dicarboxylic acid transport
IMO23_02045	COG1560	Kdo2-lipid A biosynthetic process
IMO23_02050	COG1280	lysine exporter protein (LysE YggA)
IMO23_02055	COG0488	(ABC) transporter
IMO23_02060	COG2900	Belongs to the SlyX family
IMO23_02070	COG1733	regulation of RNA biosynthetic process
IMO23_02095	COG0210	DNA helicase
IMO23_02100	COG0724	RNA recognition motif
IMO23_02120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IMO23_02120	COG4651	solute:proton antiporter activity
IMO23_02145	COG0788	formyltetrahydrofolate deformylase activity
IMO23_02235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IMO23_02260	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IMO23_02295	COG0789	Transcriptional regulator
IMO23_02305	COG2132	Multicopper oxidase
IMO23_02320	COG2205	protein histidine kinase activity
IMO23_02420	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IMO23_02420	COG2813	Specifically methylates the guanine in position
IMO23_02430	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IMO23_02440	COG4774	siderophore transport
IMO23_02450	COG0740	serine-type endopeptidase activity
IMO23_02470	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IMO23_02470	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IMO23_02475	COG0280	phosphate acetyltransferase
IMO23_02475	COG0857	belongs to the CobB CobQ family
IMO23_02480	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IMO23_02490	COG0800	Aldolase
IMO23_02500	COG3265	gluconokinase activity
IMO23_02505	COG1012	belongs to the aldehyde dehydrogenase family
IMO23_02515	COG2267	carboxylic ester hydrolase activity
IMO23_02530	COG0793	Belongs to the peptidase S41A family
IMO23_02565	COG1426	Protein conserved in bacteria
IMO23_02605	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IMO23_02615	COG1162	GTPase activity
IMO23_02620	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IMO23_02635	COG1538	Outer membrane efflux protein
IMO23_02640	COG0577	efflux transmembrane transporter activity
IMO23_02640	COG1136	(ABC) transporter
IMO23_02645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IMO23_02670	COG0028	Belongs to the TPP enzyme family
IMO23_02675	COG0440	acetolactate synthase activity
IMO23_02715	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IMO23_02730	COG0084	hydrolase, TatD family'
IMO23_02740	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IMO23_02750	COG0583	DNA-binding transcription factor activity
IMO23_02760	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IMO23_02770	COG3328	transposase activity
IMO23_02830	COG0640	Transcriptional regulator
IMO23_02840	COG0798	PFAM Bile acid sodium symporter
IMO23_02845	COG0431	NADPH-dependent FMN reductase
IMO23_02850	COG0492	ferredoxin-NADP+ reductase activity
IMO23_02855	COG2072	flavoprotein involved in K transport
IMO23_02860	COG3328	transposase activity
IMO23_02885	COG2814	Major facilitator Superfamily
IMO23_02895	COG0697	spore germination
IMO23_02925	COG3622	Belongs to the hyi family
IMO23_02930	COG2084	Dehydrogenase
IMO23_02935	COG1024	Enoyl-CoA hydratase
IMO23_02940	COG0784	Response regulator, receiver
IMO23_02940	COG2205	protein histidine kinase activity
IMO23_02940	COG5002	protein histidine kinase activity
IMO23_02960	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IMO23_02970	COG3956	TIGRFAM MazG family protein
IMO23_02975	COG1555	photosystem II stabilization
IMO23_02980	COG0617	tRNA 3'-terminal CCA addition
IMO23_02985	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IMO23_03005	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMO23_03010	COG3028	Belongs to the UPF0307 family
IMO23_03015	COG0318	PFAM AMP-dependent synthetase and ligase
IMO23_03030	COG0625	glutathione transferase activity
IMO23_03035	COG1238	metal cluster binding
IMO23_03075	COG0072	phenylalanine-tRNA ligase activity
IMO23_03105	COG0248	Ppx GppA phosphatase
IMO23_03115	COG0037	tRNA processing
IMO23_03155	COG1764	response to oxidative stress
IMO23_03160	COG1846	Transcriptional regulator
IMO23_03170	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IMO23_03230	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IMO23_03235	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IMO23_03240	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IMO23_03250	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IMO23_03290	COG1214	PFAM Peptidase M22, glycoprotease
IMO23_03315	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IMO23_03320	COG0561	phosphatase activity
IMO23_03330	COG2132	Multicopper oxidase
IMO23_03350	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IMO23_03355	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IMO23_03360	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IMO23_03390	COG0583	DNA-binding transcription factor activity
IMO23_03395	COG1960	acyl-CoA dehydrogenase activity
IMO23_03400	COG2814	Major facilitator Superfamily
IMO23_03405	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IMO23_03410	COG1309	transcriptional regulator
IMO23_03425	COG1053	succinate dehydrogenase
IMO23_03430	COG0583	DNA-binding transcription factor activity
IMO23_03445	COG0583	DNA-binding transcription factor activity
IMO23_03455	COG0583	DNA-binding transcription factor activity
IMO23_03470	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IMO23_03525	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMO23_03545	COG0745	RESPONSE REGULATOR receiver
IMO23_03595	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IMO23_03625	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IMO23_03630	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IMO23_03650	COG0583	DNA-binding transcription factor activity
IMO23_03670	COG0668	transmembrane transport
IMO23_03680	COG2081	HI0933 family
IMO23_03685	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IMO23_03715	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMO23_03715	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMO23_03725	COG0489	protein tyrosine kinase activity
IMO23_03775	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IMO23_03785	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IMO23_03800	COG0730	response to heat
IMO23_03810	COG1196	nuclear chromosome segregation
IMO23_03830	COG2223	nitrite transmembrane transporter activity
IMO23_03835	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IMO23_03840	COG1877	trehalose-phosphatase activity
IMO23_03845	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IMO23_03845	COG0596	Alpha beta hydrolase
IMO23_03845	COG2226	methyltransferase
IMO23_03860	COG4106	trans-aconitate 2-methyltransferase activity
IMO23_03880	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IMO23_03885	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IMO23_03890	COG0009	L-threonylcarbamoyladenylate synthase
IMO23_03895	COG3101	peptidyl-lysine hydroxylation
IMO23_03900	COG1399	metal-binding, possibly nucleic acid-binding protein
IMO23_03925	COG1652	LysM domain
IMO23_03930	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IMO23_03930	COG0352	thiamine-phosphate diphosphorylase activity
IMO23_03930	COG0351	phosphomethylpyrimidine kinase
IMO23_03940	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IMO23_03970	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IMO23_04000	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IMO23_04015	COG0358	DNA primase activity
IMO23_04025	COG0564	pseudouridine synthase activity
IMO23_04050	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IMO23_04070	COG0583	DNA-binding transcription factor activity
IMO23_04075	COG0473	3-isopropylmalate dehydrogenase activity
IMO23_04085	COG0657	acetylesterase activity
IMO23_04095	COG1012	belongs to the aldehyde dehydrogenase family
IMO23_04115	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IMO23_04115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IMO23_04130	COG1981	membrane
IMO23_04175	COG0456	acetyltransferase
IMO23_04185	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IMO23_04190	COG0492	ferredoxin-NADP+ reductase activity
IMO23_04195	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IMO23_04195	COG1674	ftsk spoiiie
IMO23_04200	COG1280	lysine exporter protein (LysE YggA)
IMO23_04215	COG2894	cell division
IMO23_04230	COG0204	Acyl-transferase
IMO23_04235	COG2885	chlorophyll binding
IMO23_04240	COG0210	DNA helicase
IMO23_04250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMO23_04265	COG0121	glutamine amidotransferase
IMO23_04285	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IMO23_04290	COG0735	belongs to the Fur family
IMO23_04315	COG0420	3'-5' exonuclease activity
IMO23_04335	COG1090	epimerase
IMO23_04350	COG2050	protein possibly involved in aromatic compounds catabolism
IMO23_04360	COG2814	Major facilitator Superfamily
IMO23_04365	COG0405	Gamma-glutamyltransferase
IMO23_04375	COG0582	viral genome integration into host DNA
IMO23_04490	COG0477	Major facilitator Superfamily
IMO23_04495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IMO23_04520	COG0531	amino acid
IMO23_04525	COG2040	homocysteine
IMO23_04550	COG1309	transcriptional regulator
IMO23_04555	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IMO23_04560	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IMO23_04570	COG1607	acyl-coa hydrolase
IMO23_04580	COG0523	cobalamin synthesis protein
IMO23_04590	COG4681	YaeQ
IMO23_04600	COG1649	PFAM Uncharacterised BCR, COG1649
IMO23_04600	COG0726	polysaccharide deacetylase
IMO23_04605	COG1215	transferase activity, transferring glycosyl groups
IMO23_04615	COG1024	Enoyl-CoA hydratase
IMO23_04630	COG1414	Transcriptional regulator
IMO23_04650	COG1028	Short-chain dehydrogenase reductase Sdr
IMO23_04685	COG0028	Belongs to the TPP enzyme family
IMO23_04695	COG0477	Major facilitator Superfamily
IMO23_04700	COG0242	peptide deformylase activity
IMO23_04705	COG2066	Belongs to the glutaminase family
IMO23_04710	COG2207	Transcriptional regulator
IMO23_04715	COG2223	nitrite transmembrane transporter activity
IMO23_04730	COG0583	DNA-binding transcription factor activity
IMO23_04735	COG1028	Short-chain dehydrogenase reductase Sdr
IMO23_04740	COG2271	Major facilitator Superfamily
IMO23_04745	COG3959	Transketolase, thiamine diphosphate binding domain
IMO23_04750	COG3958	Transketolase
IMO23_04760	COG0306	phosphate transporter
IMO23_04770	COG3328	transposase activity
IMO23_04790	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IMO23_04835	COG4181	ATPase activity
IMO23_04840	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IMO23_04870	COG0583	DNA-binding transcription factor activity
IMO23_04880	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IMO23_04885	COG1773	rubredoxin
IMO23_04935	COG2851	Citrate transporter
IMO23_04940	COG1253	flavin adenine dinucleotide binding
IMO23_04980	COG0804	urea catabolic process
IMO23_04990	COG0830	nickel cation binding
IMO23_05005	COG0742	ribosomal rna small subunit methyltransferase
IMO23_05010	COG0768	penicillin binding
IMO23_05035	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IMO23_05040	COG2878	Part of a membrane complex involved in electron transport
IMO23_05045	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IMO23_05055	COG3384	dioxygenase
IMO23_05075	COG3328	transposase activity
IMO23_05085	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IMO23_05125	COG0006	proline dipeptidase activity
IMO23_05130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IMO23_05135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IMO23_05155	COG1279	arginine transmembrane transporter activity
IMO23_05160	COG0583	DNA-binding transcription factor activity
IMO23_05200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IMO23_05205	COG1388	LysM domain
IMO23_05205	COG0741	lytic transglycosylase activity
IMO23_05205	COG0741	lytic transglycosylase activity
IMO23_05205	COG1388	LysM domain
IMO23_05215	COG4174	ABC transporter (Permease)
IMO23_05220	COG4239	(ABC) transporter, permease
IMO23_05225	COG4172	Belongs to the ABC transporter superfamily
IMO23_05245	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IMO23_05255	COG2203	Gaf domain
IMO23_05255	COG5001	Diguanylate cyclase
IMO23_05255	COG3706	GGDEF domain
IMO23_05255	COG4251	negative regulation of phosphorylation
IMO23_05265	COG0446	pyridine nucleotide-disulphide oxidoreductase
IMO23_05265	COG1902	pentaerythritol trinitrate reductase activity
IMO23_05315	COG0582	viral genome integration into host DNA
IMO23_05380	COG1113	amino acid transport
IMO23_05415	COG0697	spore germination
IMO23_05420	COG2721	sulfolactate sulfo-lyase activity
IMO23_05425	COG2271	Major facilitator Superfamily
IMO23_05440	COG1012	belongs to the aldehyde dehydrogenase family
IMO23_05445	COG2186	Transcriptional regulator
IMO23_05470	COG1960	acyl-CoA dehydrogenase activity
IMO23_05480	COG1012	belongs to the aldehyde dehydrogenase family
IMO23_05485	COG1024	Enoyl-CoA hydratase
IMO23_05490	COG2814	Major facilitator Superfamily
IMO23_05505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IMO23_05550	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IMO23_05565	COG0583	DNA-binding transcription factor activity
IMO23_05570	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IMO23_05575	COG2072	flavoprotein involved in K transport
IMO23_05580	COG0300	oxidoreductase activity
IMO23_05590	COG1309	transcriptional regulator
IMO23_05595	COG1741	Belongs to the pirin family
IMO23_05610	COG2072	flavoprotein involved in K transport
IMO23_05620	COG2252	PERMEase
IMO23_05625	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IMO23_05635	COG3038	cytochrome b561
IMO23_05645	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IMO23_05655	COG0527	aspartate kinase activity
IMO23_05810	COG3179	chitinase
IMO23_05855	COG0582	viral genome integration into host DNA
IMO23_05865	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IMO23_05875	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IMO23_05890	COG0667	Aldo Keto reductase
IMO23_05905	COG1765	OsmC-like protein
IMO23_05920	COG0542	response to heat
IMO23_05955	COG2885	chlorophyll binding
IMO23_05965	COG0625	glutathione transferase activity
IMO23_05990	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IMO23_06010	COG3634	alkyl hydroperoxide reductase activity
IMO23_06020	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IMO23_06030	COG0450	alkyl hydroperoxide reductase
IMO23_06035	COG1643	Atp-dependent helicase
IMO23_06050	COG2814	Major facilitator Superfamily
IMO23_06055	COG3135	benzoate transporter
IMO23_06060	COG1028	Short-chain dehydrogenase reductase Sdr
IMO23_06065	COG0633	Ferredoxin
IMO23_06065	COG0543	2 iron, 2 sulfur cluster binding
IMO23_06070	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IMO23_06075	COG4638	Rieske (2fe-2S)
IMO23_06080	COG0583	DNA-binding transcription factor activity
IMO23_06130	COG1570	exodeoxyribonuclease VII activity
IMO23_06160	COG1280	lysine exporter protein (LysE YggA)
IMO23_06165	COG1278	Cold shock
IMO23_06190	COG2801	Transposase and inactivated derivatives
IMO23_06205	COG0517	IMP dehydrogenase activity
IMO23_06205	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IMO23_06210	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IMO23_06220	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IMO23_06225	COG1137	ATPase activity
IMO23_06230	COG1538	Outer membrane efflux protein
IMO23_06260	COG4122	O-methyltransferase activity
IMO23_06270	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IMO23_06285	COG1522	sequence-specific DNA binding
IMO23_06300	COG1560	Kdo2-lipid A biosynthetic process
IMO23_06310	COG2814	Major facilitator Superfamily
IMO23_06320	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IMO23_06325	COG1116	anion transmembrane transporter activity
IMO23_06330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IMO23_06335	COG4521	taurine ABC transporter
IMO23_06355	COG1250	3-hydroxyacyl-CoA dehydrogenase
IMO23_06390	COG0583	DNA-binding transcription factor activity
IMO23_06395	COG1914	H( )-stimulated, divalent metal cation uptake system
IMO23_06415	COG4770	biotin carboxylase activity
IMO23_06420	COG0038	chloride channel
IMO23_06440	COG1063	alcohol dehydrogenase
IMO23_06455	COG0439	Biotin carboxylase
IMO23_06460	COG2249	NAD(P)H dehydrogenase (quinone) activity
IMO23_06465	COG1733	regulation of RNA biosynthetic process
IMO23_06475	COG0864	Transcriptional regulator
IMO23_06485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMO23_06530	COG2807	transmembrane transport
IMO23_06545	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IMO23_06555	COG0789	Transcriptional regulator
IMO23_06585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IMO23_06610	COG1012	belongs to the aldehyde dehydrogenase family
IMO23_06615	COG0531	amino acid
IMO23_06625	COG2030	dehydratase
IMO23_06625	COG1012	belongs to the aldehyde dehydrogenase family
IMO23_06630	COG3396	Phenylacetate-CoA oxygenase
IMO23_06635	COG3460	Phenylacetate-CoA oxygenase
IMO23_06640	COG3396	Phenylacetate-CoA oxygenase
IMO23_06645	COG2151	metal-sulfur cluster biosynthetic enzyme
IMO23_06650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IMO23_06655	COG1024	Enoyl-CoA hydratase
IMO23_06660	COG1024	Enoyl-CoA hydratase
IMO23_06665	COG1250	3-hydroxyacyl-CoA dehydrogenase
IMO23_06670	COG0183	Belongs to the thiolase family
IMO23_06675	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
IMO23_06680	COG3327	negative regulation of DNA-templated transcription, initiation
IMO23_06690	COG2050	protein possibly involved in aromatic compounds catabolism
IMO23_06700	COG0406	alpha-ribazole phosphatase activity
IMO23_06725	COG1309	transcriptional regulator
IMO23_06730	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IMO23_06745	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IMO23_06750	COG0531	amino acid
IMO23_06755	COG0753	catalase activity
IMO23_06760	COG3038	cytochrome b561
IMO23_06780	COG2267	carboxylic ester hydrolase activity
IMO23_06785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IMO23_06790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMO23_06795	COG1012	belongs to the aldehyde dehydrogenase family
IMO23_06805	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IMO23_06815	COG1012	belongs to the aldehyde dehydrogenase family
IMO23_06820	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IMO23_06825	COG0583	DNA-binding transcription factor activity
IMO23_06835	COG1414	Transcriptional regulator
IMO23_06840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IMO23_06850	COG1840	ABC-type Fe3 transport system, periplasmic component
IMO23_06855	COG3842	ATPase activity
IMO23_06870	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IMO23_06875	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IMO23_06880	COG2814	Major facilitator Superfamily
IMO23_06885	COG1960	acyl-CoA dehydrogenase activity
IMO23_06900	COG1024	Enoyl-CoA hydratase
IMO23_06915	COG2814	Major facilitator Superfamily
IMO23_06925	COG0183	Belongs to the thiolase family
IMO23_06930	COG1250	3-hydroxyacyl-CoA dehydrogenase
IMO23_06935	COG1028	Short-chain dehydrogenase reductase Sdr
IMO23_06940	COG1024	Enoyl-CoA hydratase
IMO23_06945	COG1960	acyl-CoA dehydrogenase activity
IMO23_06950	COG2814	Major facilitator Superfamily
IMO23_06955	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IMO23_06960	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IMO23_06970	COG2814	Major facilitator Superfamily
IMO23_06980	COG1960	acyl-CoA dehydrogenase activity
IMO23_06995	COG0583	DNA-binding transcription factor activity
IMO23_07005	COG4770	biotin carboxylase activity
IMO23_07010	COG1024	Enoyl-CoA hydratase
IMO23_07015	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IMO23_07020	COG1960	acyl-CoA dehydrogenase activity
IMO23_07025	COG1309	transcriptional regulator
IMO23_07030	COG0318	PFAM AMP-dependent synthetase and ligase
IMO23_07050	COG0583	DNA-binding transcription factor activity
IMO23_07100	COG1028	Short-chain dehydrogenase reductase Sdr
IMO23_07120	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IMO23_07140	COG0784	Response regulator, receiver
IMO23_07140	COG2205	protein histidine kinase activity
IMO23_07180	COG0765	amino acid transport
IMO23_07190	COG1126	abc transporter atp-binding protein
IMO23_07195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMO23_07200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMO23_07215	COG1280	lysine exporter protein (LysE YggA)
IMO23_07220	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IMO23_07225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IMO23_07230	COG1045	serine acetyltransferase
IMO23_07245	COG0583	DNA-binding transcription factor activity
IMO23_07250	COG0625	glutathione transferase activity
IMO23_07255	COG0625	glutathione transferase activity
IMO23_07260	COG0583	DNA-binding transcription factor activity
IMO23_07270	COG1346	cytolysis
IMO23_07295	COG0300	oxidoreductase activity
IMO23_07300	COG2814	Major facilitator Superfamily
IMO23_07310	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
IMO23_07315	COG3052	prosthetic group binding
IMO23_07335	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IMO23_07355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IMO23_07365	COG1294	oxidase, subunit
IMO23_07370	COG1271	oxidase subunit
IMO23_07395	COG0477	Major facilitator Superfamily
IMO23_07405	COG4521	taurine ABC transporter
IMO23_07410	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IMO23_07415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IMO23_07420	COG2175	clavaminate synthase activity
IMO23_07430	COG1953	Uracil, thiamine, allantoin
IMO23_07440	COG0583	DNA-binding transcription factor activity
IMO23_07450	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IMO23_07465	COG0640	Transcriptional regulator
IMO23_07475	COG0583	DNA-binding transcription factor activity
IMO23_07490	COG3634	alkyl hydroperoxide reductase activity
IMO23_07530	COG0436	Aminotransferase
IMO23_07540	COG0386	Belongs to the glutathione peroxidase family
IMO23_07580	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IMO23_07605	COG0012	GTP binding
IMO23_07610	COG2011	ABC-type metal ion transport system permease component
IMO23_07615	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IMO23_07625	COG1464	Belongs to the NlpA lipoprotein family
IMO23_07660	COG0765	amino acid transport
IMO23_07665	COG0765	amino acid transport
IMO23_07670	COG1126	abc transporter atp-binding protein
IMO23_07680	COG1522	sequence-specific DNA binding
IMO23_07695	COG1309	transcriptional regulator
IMO23_07735	COG3293	Transposase
IMO23_07750	COG3121	Chaperone
IMO23_07755	COG3539	Fimbrial protein
IMO23_07780	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IMO23_07780	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IMO23_07825	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IMO23_07835	COG2353	YceI-like domain
IMO23_07845	COG3698	Phosphodiester glycosidase
IMO23_07860	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IMO23_07865	COG0506	proline dehydrogenase activity
IMO23_07865	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IMO23_07865	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IMO23_07875	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IMO23_07880	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IMO23_07900	COG1132	(ABC) transporter
IMO23_07905	COG3122	Protein conserved in bacteria
IMO23_07910	COG3619	membrane
IMO23_07920	COG0640	Transcriptional regulator
IMO23_07930	COG2850	peptidyl-arginine hydroxylation
IMO23_07935	COG0424	maF-like protein
IMO23_07955	COG0191	fructose-bisphosphate aldolase activity
IMO23_07960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IMO23_07975	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IMO23_07985	COG1192	Involved in chromosome partitioning
IMO23_07990	COG1475	DNA binding
IMO23_07995	COG0811	peptide transport
IMO23_08005	COG1132	(ABC) transporter
IMO23_08010	COG1663	tetraacyldisaccharide 4'-kinase activity
IMO23_08030	COG0084	hydrolase, TatD family'
IMO23_08095	COG0776	regulation of translation
IMO23_08125	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IMO23_08130	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IMO23_08180	COG0339	signal peptide processing
IMO23_08190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMO23_08225	COG0702	epimerase
IMO23_08230	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IMO23_08250	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IMO23_08280	COG0316	Belongs to the HesB IscA family
IMO23_08285	COG0822	iron-sulfur transferase activity
IMO23_08310	COG0776	regulation of translation
IMO23_08315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IMO23_08320	COG2207	Transcriptional regulator
IMO23_08325	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IMO23_08330	COG1960	acyl-CoA dehydrogenase activity
IMO23_08335	COG1960	acyl-CoA dehydrogenase activity
IMO23_08350	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IMO23_08375	COG3293	Transposase
IMO23_08385	COG4264	IucA IucC family
IMO23_08395	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IMO23_08425	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IMO23_08440	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IMO23_08445	COG0406	alpha-ribazole phosphatase activity
IMO23_08460	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IMO23_08465	COG0730	response to heat
IMO23_08485	COG4773	Receptor
IMO23_08490	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IMO23_08505	COG1131	(ABC) transporter
IMO23_08510	COG0842	Transport permease protein
IMO23_08515	COG0842	Transport permease protein
IMO23_08575	COG2226	methyltransferase
IMO23_08605	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IMO23_08640	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IMO23_08650	COG0133	tryptophan synthase activity
IMO23_08665	COG3706	GGDEF domain
IMO23_08680	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IMO23_08685	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IMO23_08690	COG0022	dehydrogenase e1 component
IMO23_08695	COG0508	dehydrogenase complex catalyzes the overall conversion of
IMO23_08700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMO23_08710	COG1063	alcohol dehydrogenase
IMO23_08715	COG3781	membrane
IMO23_08725	COG3453	Protein conserved in bacteria
IMO23_08725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IMO23_08735	COG0730	response to heat
IMO23_08750	COG2207	Transcriptional regulator
IMO23_08750	COG3708	Transcriptional regulator
IMO23_08755	COG1733	regulation of RNA biosynthetic process
IMO23_08760	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IMO23_08785	COG4521	taurine ABC transporter
IMO23_08800	COG0477	Major facilitator Superfamily
IMO23_08810	COG1027	Aspartate ammonia-lyase
IMO23_08825	COG0583	DNA-binding transcription factor activity
IMO23_08830	COG0583	DNA-binding transcription factor activity
IMO23_08835	COG0183	Belongs to the thiolase family
IMO23_08840	COG2031	fatty acid transporter
IMO23_08855	COG0583	DNA-binding transcription factor activity
IMO23_08875	COG1309	transcriptional regulator
IMO23_08885	COG2610	gluconate transmembrane transporter activity
IMO23_08890	COG1028	Short-chain dehydrogenase reductase Sdr
IMO23_08910	COG0543	2 iron, 2 sulfur cluster binding
IMO23_08910	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IMO23_08915	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IMO23_08930	COG0725	ABC transporter, periplasmic molybdate-binding protein
IMO23_08935	COG4149	molybdate abc transporter
IMO23_08940	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IMO23_08945	COG1028	Short-chain dehydrogenase reductase Sdr
IMO23_08950	COG1535	isochorismatase
IMO23_08950	COG3433	isochorismatase activity
IMO23_09020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IMO23_09035	COG0753	catalase activity
IMO23_09045	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IMO23_09070	COG3539	Fimbrial protein
IMO23_09080	COG1484	DNA-dependent DNA replication
IMO23_09085	COG4584	PFAM Integrase catalytic
IMO23_09110	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
IMO23_09115	COG0732	type I restriction modification DNA specificity domain
IMO23_09155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IMO23_09170	COG3706	GGDEF domain
IMO23_09225	COG0542	response to heat
IMO23_09230	COG0071	Belongs to the small heat shock protein (HSP20) family
IMO23_09265	COG2130	NADP-dependent
IMO23_09270	COG1309	transcriptional regulator
IMO23_09280	COG1902	pentaerythritol trinitrate reductase activity
IMO23_09290	COG1979	alcohol dehydrogenase
IMO23_09305	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IMO23_09325	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IMO23_09325	COG0475	glutathione-regulated potassium exporter activity
IMO23_09390	COG1120	ATPase activity
IMO23_09395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMO23_09405	COG1064	alcohol dehydrogenase
IMO23_09415	COG2084	Dehydrogenase
IMO23_09425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMO23_09430	COG0583	DNA-binding transcription factor activity
IMO23_09440	COG0129	dihydroxy-acid dehydratase activity
IMO23_09445	COG1012	belongs to the aldehyde dehydrogenase family
IMO23_09475	COG0583	DNA-binding transcription factor activity
IMO23_09490	COG2188	Transcriptional regulator
IMO23_09550	COG3293	Transposase
IMO23_09570	COG0789	Transcriptional regulator
IMO23_09585	COG1902	pentaerythritol trinitrate reductase activity
IMO23_09585	COG0446	pyridine nucleotide-disulphide oxidoreductase
IMO23_09600	COG1012	belongs to the aldehyde dehydrogenase family
IMO23_09620	COG2186	Transcriptional regulator
IMO23_09630	COG0583	DNA-binding transcription factor activity
IMO23_09635	COG4948	Mandelate Racemase Muconate Lactonizing
IMO23_09640	COG4829	muconolactone delta-isomerase
IMO23_09650	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IMO23_09655	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IMO23_09660	COG0183	Belongs to the thiolase family
IMO23_09665	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IMO23_09675	COG1012	belongs to the aldehyde dehydrogenase family
IMO23_09685	COG3733	amine oxidase
IMO23_09695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IMO23_09705	COG1028	Short-chain dehydrogenase reductase Sdr
IMO23_09715	COG4638	Rieske (2fe-2S)
IMO23_09745	COG2814	Major facilitator Superfamily
IMO23_09770	COG1960	acyl-CoA dehydrogenase activity
IMO23_09775	COG0583	DNA-binding transcription factor activity
IMO23_09780	COG1414	Transcriptional regulator
IMO23_09795	COG2391	methyltransferase activity
IMO23_09805	COG4993	Dehydrogenase
IMO23_09810	COG3659	wide pore channel activity
IMO23_09815	COG3420	alginic acid biosynthetic process
IMO23_09820	COG0710	3-dehydroquinate dehydratase activity
IMO23_09825	COG3485	protocatechuate 3,4-dioxygenase
IMO23_09830	COG3485	protocatechuate 3,4-dioxygenase
IMO23_09835	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IMO23_09840	COG2271	Major facilitator Superfamily
IMO23_09845	COG0596	Alpha beta hydrolase
IMO23_09850	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IMO23_09855	COG0183	Belongs to the thiolase family
IMO23_09860	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IMO23_09865	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IMO23_09875	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IMO23_09880	COG2323	membrane
IMO23_09925	COG1902	pentaerythritol trinitrate reductase activity
IMO23_09925	COG0446	pyridine nucleotide-disulphide oxidoreductase
IMO23_09950	COG0542	response to heat
IMO23_09955	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IMO23_09985	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IMO23_09990	COG0569	domain protein
IMO23_09995	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IMO23_10025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMO23_10035	COG1585	Membrane protein implicated in regulation of membrane protease activity
IMO23_10050	COG1294	oxidase, subunit
IMO23_10055	COG4890	Cyd operon protein YbgT
IMO23_10070	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
IMO23_10080	COG0552	protein localization to endoplasmic reticulum
IMO23_10105	COG0516	GMP reductase activity
IMO23_10105	COG0517	IMP dehydrogenase activity
IMO23_10110	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IMO23_10115	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IMO23_10125	COG0583	DNA-binding transcription factor activity
IMO23_10130	COG0024	Methionine aminopeptidase
IMO23_10160	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMO23_10160	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IMO23_10165	COG1105	Belongs to the carbohydrate kinase PfkB family
IMO23_10170	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IMO23_10170	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IMO23_10170	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IMO23_10195	COG5001	Diguanylate cyclase
IMO23_10195	COG3300	MHYT domain
IMO23_10210	COG2135	peptidase activity
IMO23_10215	COG0659	secondary active sulfate transmembrane transporter activity
IMO23_10230	COG1113	amino acid transport
IMO23_10240	COG1522	sequence-specific DNA binding
IMO23_10270	COG1011	Hydrolase
IMO23_10275	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IMO23_10285	COG2137	regulation of response to DNA damage stimulus
IMO23_10300	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IMO23_10320	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IMO23_10335	COG0575	Belongs to the CDS family
IMO23_10340	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IMO23_10365	COG3852	Histidine kinase
IMO23_10370	COG2204	response regulator
IMO23_10430	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IMO23_10435	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IMO23_10455	COG0697	spore germination
IMO23_10460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IMO23_10470	COG0303	'Molybdopterin
IMO23_10475	COG0315	cyclic pyranopterin monophosphate synthase activity
IMO23_10475	COG0521	Mo-molybdopterin cofactor biosynthetic process
IMO23_10490	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IMO23_10495	COG0243	molybdopterin cofactor binding
IMO23_10505	COG0243	molybdopterin cofactor binding
IMO23_10510	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IMO23_10515	COG2146	nitrite reductase [NAD(P)H] activity
IMO23_10515	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IMO23_10525	COG0745	RESPONSE REGULATOR receiver
IMO23_10530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IMO23_10530	COG1116	anion transmembrane transporter activity
IMO23_10545	COG0511	ligase activity, forming carbon-carbon bonds
IMO23_10550	COG0439	Biotin carboxylase
IMO23_10560	COG2814	Major facilitator Superfamily
IMO23_10770	COG5410	chromosome segregation
IMO23_10955	COG0069	glutamate synthase activity
IMO23_10975	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IMO23_10985	COG1454	alcohol dehydrogenase
IMO23_10990	COG0824	Thioesterase
IMO23_11005	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IMO23_11020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IMO23_11025	COG2030	dehydratase
IMO23_11035	COG0183	Belongs to the thiolase family
IMO23_11045	COG0583	DNA-binding transcription factor activity
IMO23_11050	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IMO23_11060	COG1522	sequence-specific DNA binding
IMO23_11065	COG3135	benzoate transporter
IMO23_11075	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IMO23_11100	COG0589	response to stress
IMO23_11130	COG4773	Receptor
IMO23_11175	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IMO23_11190	COG1605	Chorismate mutase
IMO23_11235	COG0308	aminopeptidase N
IMO23_11255	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IMO23_11265	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IMO23_11270	COG1454	alcohol dehydrogenase
IMO23_11290	COG0531	amino acid
IMO23_11295	COG4303	Ethanolamine ammonia lyase large subunit
IMO23_11300	COG4302	ethanolamine ammonia-lyase activity
IMO23_11305	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IMO23_11305	COG0519	Catalyzes the synthesis of GMP from XMP
IMO23_11310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IMO23_11335	COG0697	spore germination
IMO23_11340	COG1923	regulation of RNA biosynthetic process
IMO23_11350	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IMO23_11355	COG0802	atpase or kinase
IMO23_11375	COG1187	pseudouridine synthase activity
IMO23_11390	COG0583	DNA-binding transcription factor activity
IMO23_11405	COG2814	Major facilitator Superfamily
IMO23_11410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IMO23_11435	COG0729	surface antigen
IMO23_11460	COG3293	Transposase
IMO23_11470	COG3293	Transposase
IMO23_11475	COG0745	RESPONSE REGULATOR receiver
IMO23_11480	COG2205	protein histidine kinase activity
IMO23_11490	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IMO23_11495	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IMO23_11520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IMO23_11525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IMO23_11530	COG1960	acyl-CoA dehydrogenase activity
IMO23_11575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMO23_11585	COG3658	cytochrome
IMO23_11590	COG1215	transferase activity, transferring glycosyl groups
IMO23_11625	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IMO23_11630	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IMO23_11640	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IMO23_11665	COG0305	Participates in initiation and elongation during chromosome replication
IMO23_11670	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IMO23_11680	COG1305	Transglutaminase-like
IMO23_11730	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IMO23_11735	COG0138	bifunctional purine biosynthesis protein purh
IMO23_11740	COG0151	Belongs to the GarS family
IMO23_11745	COG1464	Belongs to the NlpA lipoprotein family
IMO23_11750	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IMO23_11755	COG2011	ABC-type metal ion transport system permease component
IMO23_11760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IMO23_11770	COG1301	dicarboxylic acid transport
IMO23_11800	COG1794	racemase activity, acting on amino acids and derivatives
IMO23_11820	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IMO23_11820	COG3008	intermembrane lipid transfer
IMO23_11825	COG2995	paraquat-inducible protein a
IMO23_11850	COG0477	Major facilitator Superfamily
IMO23_11860	COG2186	Transcriptional regulator
IMO23_11870	COG0786	glutamate:sodium symporter activity
IMO23_11875	COG3243	poly(R)-hydroxyalkanoic acid synthase
IMO23_11895	COG3111	PFAM Bacterial OB fold (BOF) protein
IMO23_11980	COG0515	serine threonine protein kinase
IMO23_12010	COG1610	YqeY-like protein
IMO23_12040	COG1286	toxin biosynthetic process
IMO23_12070	COG0778	Nitroreductase
IMO23_12080	COG0513	Belongs to the DEAD box helicase family
IMO23_12100	COG2363	Small membrane protein
IMO23_12125	COG4650	regulator
IMO23_12130	COG1234	tRNA 3'-trailer cleavage
IMO23_12135	COG1690	Belongs to the RtcB family
IMO23_12155	COG2195	Cleaves the N-terminal amino acid of tripeptides
IMO23_12165	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IMO23_12180	COG1960	acyl-CoA dehydrogenase activity
IMO23_12185	COG1301	dicarboxylic acid transport
IMO23_12190	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IMO23_12195	COG3139	Protein of unknown function (DUF1315)
IMO23_12200	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IMO23_12205	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IMO23_12215	COG0494	nUDIX hydrolase
IMO23_12225	COG0642	Histidine kinase
IMO23_12240	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IMO23_12250	COG1720	tRNA m6t6A37 methyltransferase activity
IMO23_12265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IMO23_12270	COG0826	peptidase U32
IMO23_12275	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IMO23_12285	COG4598	ABC transporter
IMO23_12290	COG4160	amino acid transport
IMO23_12295	COG4215	(ABC) transporter
IMO23_12310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IMO23_12355	COG1131	(ABC) transporter
IMO23_12360	COG0842	Transport permease protein
IMO23_12375	COG0772	Belongs to the SEDS family
IMO23_12380	COG2951	lytic endotransglycosylase activity
IMO23_12405	COG2207	Transcriptional regulator
IMO23_12420	COG0052	Belongs to the universal ribosomal protein uS2 family
IMO23_12425	COG0024	Methionine aminopeptidase
IMO23_12435	COG2223	nitrite transmembrane transporter activity
IMO23_12445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMO23_12450	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IMO23_12455	COG1960	acyl-CoA dehydrogenase activity
IMO23_12470	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IMO23_12475	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IMO23_12480	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IMO23_12500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IMO23_12505	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IMO23_12510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IMO23_12545	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IMO23_12555	COG0174	glutamine synthetase
IMO23_12570	COG0512	Glutamine amidotransferase of anthranilate synthase
IMO23_12575	COG0308	aminopeptidase N
IMO23_12605	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IMO23_12615	COG0302	gtp cyclohydrolase
IMO23_12635	COG3739	integral membrane protein
IMO23_12650	COG1169	isochorismate synthase
IMO23_12660	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
IMO23_12665	COG1132	(ABC) transporter
IMO23_12670	COG1132	(ABC) transporter
IMO23_12685	COG3433	isochorismatase activity
IMO23_12685	COG1535	isochorismatase
IMO23_12690	COG1021	2,3-dihydroxybenzoate-AMP ligase
IMO23_12695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IMO23_12695	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
IMO23_12705	COG4774	siderophore transport
IMO23_12710	COG4607	ABC-type enterochelin transport system periplasmic component
IMO23_12715	COG4604	ABC transporter, ATP-binding protein
IMO23_12720	COG4605	iron ion homeostasis
IMO23_12725	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMO23_12730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IMO23_12745	COG2964	Protein conserved in bacteria
IMO23_12785	COG2879	small protein
IMO23_12790	COG1966	Carbon starvation protein
IMO23_12810	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IMO23_12835	COG1067	ATP-dependent peptidase activity
IMO23_12840	COG0583	DNA-binding transcription factor activity
IMO23_12865	COG1686	Belongs to the peptidase S11 family
IMO23_12870	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IMO23_12910	COG0616	signal peptide processing
IMO23_12915	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IMO23_12925	COG0573	inorganic phosphate transmembrane transporter activity
IMO23_12930	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IMO23_12935	COG1113	amino acid transport
IMO23_12940	COG3961	Belongs to the TPP enzyme family
IMO23_12945	COG1522	sequence-specific DNA binding
IMO23_12955	COG0076	glutamate decarboxylase activity
IMO23_12960	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IMO23_12970	COG0583	DNA-binding transcription factor activity
IMO23_12975	COG2249	NAD(P)H dehydrogenase (quinone) activity
IMO23_12985	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IMO23_13020	COG0352	thiamine-phosphate diphosphorylase activity
IMO23_13045	COG0612	Peptidase, M16
IMO23_13055	COG1823	symporter activity
IMO23_13060	COG0583	DNA-binding transcription factor activity
IMO23_13065	COG0477	Major facilitator Superfamily
IMO23_13090	COG1187	pseudouridine synthase activity
IMO23_13105	COG1686	Belongs to the peptidase S11 family
IMO23_13110	COG1252	NADH dehydrogenase
IMO23_13120	COG0415	Belongs to the DNA photolyase family
IMO23_13135	COG1215	transferase activity, transferring glycosyl groups
IMO23_13165	COG2070	2-Nitropropane dioxygenase
IMO23_13220	COG0556	nucleotide-excision repair
IMO23_13240	COG0436	Aminotransferase
IMO23_13270	COG4221	oxidoreductase activity
IMO23_13280	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IMO23_13285	COG1381	Involved in DNA repair and RecF pathway recombination
IMO23_13295	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IMO23_13310	COG0681	Belongs to the peptidase S26 family
IMO23_13320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IMO23_13330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IMO23_13350	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IMO23_13355	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IMO23_13360	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IMO23_13370	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IMO23_13375	COG4208	sulfate ABC transporter
IMO23_13380	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IMO23_13385	COG0583	DNA-binding transcription factor activity
IMO23_13390	COG4625	pathogenesis
IMO23_13405	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IMO23_13420	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IMO23_13430	COG1056	cytidyltransferase-related domain
IMO23_13430	COG1051	belongs to the nudix hydrolase family
IMO23_13435	COG1024	Enoyl-CoA hydratase
IMO23_13440	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IMO23_13445	COG2814	Major facilitator Superfamily
IMO23_13450	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IMO23_13450	COG0047	phosphoribosylformylglycinamidine synthase activity
IMO23_13470	COG1473	amidohydrolase
IMO23_13475	COG0824	Thioesterase
IMO23_13495	COG0823	Involved in the tonB-independent uptake of proteins
IMO23_13515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMO23_13570	COG0628	permease
IMO23_13580	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IMO23_13585	COG0596	Alpha beta hydrolase
IMO23_13590	COG0616	signal peptide processing
IMO23_13590	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IMO23_13605	COG1136	(ABC) transporter
IMO23_13610	COG4591	ABC-type transport system involved in lipoprotein release permease component
IMO23_13640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IMO23_13660	COG0463	Glycosyl transferase, family 2
IMO23_13690	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IMO23_13695	COG1280	lysine exporter protein (LysE YggA)
IMO23_13705	COG0019	diaminopimelate decarboxylase activity
IMO23_13715	COG1113	amino acid transport
IMO23_13740	COG3339	Conserved Protein
IMO23_13745	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IMO23_13750	COG0243	molybdopterin cofactor binding
IMO23_13755	COG1929	Belongs to the glycerate kinase type-1 family
IMO23_13765	COG0300	oxidoreductase activity
IMO23_13770	COG0778	Nitroreductase
IMO23_13790	COG3811	Belongs to the UPF0386 family
IMO23_13815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IMO23_13830	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IMO23_13850	COG0741	lytic transglycosylase activity
IMO23_13870	COG0584	glycerophosphoryl diester phosphodiesterase
IMO23_13875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IMO23_13895	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IMO23_13900	COG1597	lipid kinase activity
IMO23_13915	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IMO23_13920	COG0477	Major facilitator Superfamily
IMO23_13970	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IMO23_13975	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IMO23_14000	COG0505	Belongs to the CarA family
IMO23_14015	COG1309	transcriptional regulator
IMO23_14020	COG0251	oxidation-reduction process
IMO23_14030	COG0589	response to stress
IMO23_14045	COG2843	Capsule synthesis protein
IMO23_14065	COG2321	neutral zinc metallopeptidase
IMO23_14070	COG2354	Protein conserved in bacteria
IMO23_14090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMO23_14115	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IMO23_14120	COG1053	succinate dehydrogenase
IMO23_14125	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IMO23_14130	COG2009	succinate dehydrogenase
IMO23_14165	COG2921	Belongs to the UPF0250 family
IMO23_14170	COG0321	lipoyl(octanoyl) transferase activity
IMO23_14185	COG0531	amino acid
IMO23_14195	COG1733	regulation of RNA biosynthetic process
IMO23_14200	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IMO23_14205	COG1648	precorrin-2 dehydrogenase activity
IMO23_14205	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IMO23_14220	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IMO23_14250	COG0671	phosphoesterase, PA-phosphatase related
IMO23_14255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IMO23_14265	COG1538	Outer membrane efflux protein
IMO23_14270	COG0393	Putative heavy-metal-binding
IMO23_14275	COG0393	Putative heavy-metal-binding
IMO23_14285	COG1028	Short-chain dehydrogenase reductase Sdr
IMO23_14295	COG0525	valine-tRNA ligase activity
IMO23_14300	COG2226	methyltransferase
IMO23_14315	COG0583	DNA-binding transcription factor activity
IMO23_14320	COG0004	ammonium transporteR
IMO23_14330	COG0642	Histidine kinase
IMO23_14335	COG0745	RESPONSE REGULATOR receiver
IMO23_14340	COG2194	sulfuric ester hydrolase activity
IMO23_14360	COG1752	Esterase of the alpha-beta hydrolase superfamily
IMO23_14375	COG2315	Protein conserved in bacteria
IMO23_14380	COG0142	geranyltranstransferase activity
IMO23_14385	COG2828	Protein conserved in bacteria
IMO23_14390	COG1113	amino acid transport
IMO23_14400	COG0582	viral genome integration into host DNA
IMO23_14435	COG0305	Participates in initiation and elongation during chromosome replication
IMO23_14485	COG0464	growth
IMO23_14505	COG2207	Transcriptional regulator
IMO23_14530	COG2249	NAD(P)H dehydrogenase (quinone) activity
IMO23_14540	COG0560	Phosphoserine phosphatase
IMO23_14550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IMO23_14560	COG1530	ribonuclease E activity
IMO23_14565	COG0424	maF-like protein
IMO23_14570	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IMO23_14575	COG1792	Involved in formation and maintenance of cell shape
IMO23_14580	COG1077	Cell shape determining protein MreB Mrl
IMO23_14585	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IMO23_14595	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IMO23_14620	COG3590	peptidase
IMO23_14640	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IMO23_14645	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IMO23_14650	COG1752	Esterase of the alpha-beta hydrolase superfamily
IMO23_14655	COG1115	amino acid carrier protein
IMO23_14675	COG2814	Major facilitator Superfamily
IMO23_14680	COG1289	transmembrane transporter activity
IMO23_14690	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IMO23_14730	COG1376	ErfK ybiS ycfS ynhG family protein
IMO23_14735	COG2832	Protein of unknown function (DUF454)
IMO23_14745	COG5510	response to toxic substance
IMO23_14760	COG0840	transmembrane signaling receptor activity
IMO23_14800	COG3422	double-strand break repair
IMO23_14805	COG2824	Alkylphosphonate utilization operon protein PhnA
IMO23_14810	COG3189	MarR family transcriptional regulator
IMO23_14815	COG0596	Alpha beta hydrolase
IMO23_14820	COG0778	Nitroreductase
IMO23_14825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMO23_14830	COG1335	isochorismatase
IMO23_14835	COG0251	oxidation-reduction process
IMO23_14840	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IMO23_14845	COG2233	PERMEase
IMO23_14870	COG0354	folic acid binding
IMO23_14875	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IMO23_14885	COG0679	Auxin Efflux Carrier
IMO23_14890	COG1902	pentaerythritol trinitrate reductase activity
IMO23_14895	COG4772	TonB-dependent receptor
IMO23_14900	COG2094	Belongs to the DNA glycosylase MPG family
IMO23_14925	COG1217	gtp-binding protein TYPA
IMO23_14930	COG2233	PERMEase
IMO23_14940	COG0833	amino acid
IMO23_14945	COG1690	Belongs to the RtcB family
IMO23_14955	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IMO23_14955	COG2885	chlorophyll binding
IMO23_14965	COG0183	Belongs to the thiolase family
IMO23_14985	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IMO23_15005	COG2207	Transcriptional regulator
IMO23_15010	COG0183	Belongs to the thiolase family
IMO23_15040	COG1272	protein, Hemolysin III
IMO23_15045	COG0477	Major facilitator Superfamily
IMO23_15060	COG0450	alkyl hydroperoxide reductase
IMO23_15080	COG0285	dihydrofolate synthase activity
IMO23_15130	COG2096	Adenosyltransferase
IMO23_15150	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IMO23_15155	COG0745	RESPONSE REGULATOR receiver
IMO23_15160	COG2205	protein histidine kinase activity
IMO23_15170	COG1960	acyl-CoA dehydrogenase activity
IMO23_15175	COG1960	acyl-CoA dehydrogenase activity
IMO23_15225	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IMO23_15240	COG0438	transferase activity, transferring glycosyl groups
IMO23_15245	COG0463	Glycosyl transferase, family 2
IMO23_15250	COG0726	polysaccharide deacetylase
IMO23_15270	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IMO23_15275	COG2205	protein histidine kinase activity
IMO23_15280	COG2026	Addiction module toxin, RelE StbE family
IMO23_15310	COG0582	viral genome integration into host DNA
IMO23_15345	COG1862	Preprotein translocase
IMO23_15355	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IMO23_15365	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IMO23_15390	COG3781	membrane
IMO23_15395	COG0613	PHP domain protein
IMO23_15405	COG2350	Protein conserved in bacteria
IMO23_15435	COG1607	acyl-coa hydrolase
IMO23_15495	COG2199	diguanylate cyclase activity
IMO23_15505	COG1408	metallophosphoesterase
IMO23_15510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IMO23_15520	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IMO23_15540	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IMO23_15545	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IMO23_15560	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IMO23_15570	COG2969	positive regulation of protein catabolic process
IMO23_15590	COG1960	acyl-CoA dehydrogenase activity
IMO23_15595	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IMO23_15610	COG1309	transcriptional regulator
IMO23_15615	COG3328	transposase activity
IMO23_15620	COG3293	Transposase
IMO23_15625	COG1960	acyl-CoA dehydrogenase activity
IMO23_15670	COG1183	phosphatidylcholine synthase activity
IMO23_15675	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IMO23_15705	COG0739	heme binding
IMO23_15705	COG0741	lytic transglycosylase activity
IMO23_15705	COG1196	nuclear chromosome segregation
IMO23_15715	COG1702	phosphate starvation-inducible protein PhoH
IMO23_15750	COG1295	ribonuclease BN
IMO23_15755	COG0697	spore germination
IMO23_15760	COG2169	Transcriptional regulator
IMO23_15765	COG0179	Fumarylacetoacetate (FAA) hydrolase
IMO23_15785	COG3293	Transposase
IMO23_15815	COG0557	exoribonuclease II activity
IMO23_15820	COG0339	signal peptide processing
IMO23_15825	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IMO23_15865	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IMO23_15870	COG1960	acyl-CoA dehydrogenase activity
IMO23_16025	COG0626	cystathionine gamma-synthase activity
IMO23_16030	COG0433	COG0433 Predicted ATPase
IMO23_16040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IMO23_16040	COG1017	nitric oxide dioxygenase activity
IMO23_16045	COG1959	2 iron, 2 sulfur cluster binding
IMO23_16060	COG1301	dicarboxylic acid transport
IMO23_16065	COG1946	Acyl-CoA thioesterase
IMO23_16085	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IMO23_16090	COG1040	competence protein
IMO23_16095	COG0494	nUDIX hydrolase
IMO23_16105	COG0598	Magnesium transport protein CorA
IMO23_16115	COG2854	intermembrane phospholipid transfer
IMO23_16125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IMO23_16130	COG1127	ABC transporter
IMO23_16140	COG0513	Belongs to the DEAD box helicase family
IMO23_16160	COG0408	coproporphyrinogen oxidase activity
IMO23_16175	COG1960	acyl-CoA dehydrogenase activity
IMO23_16190	COG1983	PspC domain protein
IMO23_16195	COG0517	IMP dehydrogenase activity
IMO23_16240	COG0583	DNA-binding transcription factor activity
IMO23_16280	COG1012	belongs to the aldehyde dehydrogenase family
IMO23_16290	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IMO23_16295	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IMO23_16300	COG0833	amino acid
IMO23_16330	COG1192	Involved in chromosome partitioning
IMO23_16335	COG0628	permease
IMO23_16345	COG1289	transmembrane transporter activity
IMO23_16360	COG2249	NAD(P)H dehydrogenase (quinone) activity
IMO23_16365	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IMO23_16375	COG0277	FAD linked oxidase domain protein
IMO23_16380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IMO23_16405	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IMO23_16410	COG5380	lipid catabolic process
IMO23_16430	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IMO23_16480	COG0194	GDP metabolic process
IMO23_16495	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IMO23_16515	COG3307	-O-antigen
IMO23_16530	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IMO23_16535	COG1704	LemA family
IMO23_16555	COG0493	'glutamate synthase
IMO23_16560	COG0070	glutamate synthase
IMO23_16560	COG0069	glutamate synthase activity
IMO23_16560	COG0067	glutamate synthase
IMO23_16610	COG2226	methyltransferase
IMO23_16625	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IMO23_16630	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IMO23_16675	COG0833	amino acid
IMO23_16760	COG0488	(ABC) transporter
IMO23_16765	COG2873	o-acetylhomoserine
IMO23_16770	COG4221	oxidoreductase activity
IMO23_16775	COG0659	secondary active sulfate transmembrane transporter activity
IMO23_16800	COG0427	acetyl-CoA hydrolase
IMO23_16830	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IMO23_16870	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IMO23_16940	COG2249	NAD(P)H dehydrogenase (quinone) activity
IMO23_16955	COG0667	Aldo Keto reductase
IMO23_16975	COG3293	Transposase
IMO23_16985	COG0583	DNA-binding transcription factor activity
IMO23_16990	COG2814	Major facilitator Superfamily
IMO23_17020	COG1335	isochorismatase
IMO23_17030	COG1012	belongs to the aldehyde dehydrogenase family
IMO23_17035	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IMO23_17045	COG1113	amino acid transport
IMO23_17055	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IMO23_17070	COG2814	Major facilitator Superfamily
IMO23_17080	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IMO23_17080	COG0352	thiamine-phosphate diphosphorylase activity
IMO23_17080	COG0351	phosphomethylpyrimidine kinase
IMO23_17100	COG1309	transcriptional regulator
IMO23_17120	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IMO23_17130	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IMO23_17135	COG3162	membrane
IMO23_17140	COG2198	Histidine kinase
IMO23_17140	COG2205	protein histidine kinase activity
IMO23_17140	COG0784	Response regulator, receiver
IMO23_17165	COG1522	sequence-specific DNA binding
IMO23_17170	COG1335	isochorismatase
IMO23_17175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IMO23_17185	COG0668	transmembrane transport
IMO23_17190	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IMO23_17195	COG1519	Transferase
IMO23_17200	COG1902	pentaerythritol trinitrate reductase activity
IMO23_17220	COG3328	transposase activity
IMO23_17225	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IMO23_17250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IMO23_17250	COG0426	domain, Protein
IMO23_17255	COG4774	siderophore transport
IMO23_17260	COG2119	membrane
IMO23_17270	COG0508	dehydrogenase complex catalyzes the overall conversion of
IMO23_17280	COG4942	peptidase
IMO23_17295	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IMO23_17305	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IMO23_17325	COG0189	ligase activity
IMO23_17345	COG0708	Exodeoxyribonuclease III
IMO23_17350	COG1393	Belongs to the ArsC family
IMO23_17365	COG3706	GGDEF domain
IMO23_17400	COG2351	hydroxyisourate hydrolase activity
IMO23_17405	COG2233	PERMEase
IMO23_17415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IMO23_17425	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
IMO23_17435	COG3150	esterase
IMO23_17465	COG2918	glutathione biosynthetic process
IMO23_17480	COG2733	membrane
IMO23_17485	COG0436	Aminotransferase
IMO23_17490	COG0534	Mate efflux family protein
IMO23_17575	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IMO23_17580	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IMO23_17590	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IMO23_17625	COG1280	lysine exporter protein (LysE YggA)
IMO23_17630	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IMO23_17645	COG0010	Belongs to the arginase family
IMO23_17675	COG2188	Transcriptional regulator
IMO23_17685	COG0523	cobalamin synthesis protein
IMO23_17695	COG1113	amino acid transport
IMO23_17705	COG0625	glutathione transferase activity
IMO23_17725	COG1683	Conserved Protein
IMO23_17730	COG0534	Mate efflux family protein
IMO23_17735	COG0385	Bile acid
IMO23_17740	COG1335	isochorismatase
IMO23_17745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IMO23_17770	COG2116	formate transmembrane transporter activity
IMO23_17775	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IMO23_17780	COG2133	pyrroloquinoline quinone binding
IMO23_17785	COG2983	Belongs to the UPF0260 family
IMO23_17805	COG1194	a g-specific adenine glycosylase
IMO23_17820	COG2818	Glycosylase
IMO23_17825	COG1064	alcohol dehydrogenase
IMO23_17830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IMO23_17845	COG0583	DNA-binding transcription factor activity
IMO23_17850	COG0656	L-ascorbic acid biosynthetic process
IMO23_17855	COG2814	Major facilitator Superfamily
IMO23_17890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IMO23_17905	COG2233	PERMEase
IMO23_17910	COG0583	DNA-binding transcription factor activity
IMO23_17945	COG0733	neurotransmitter:sodium symporter activity
IMO23_17985	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IMO23_17990	COG0657	acetylesterase activity
IMO23_18045	COG2951	lytic endotransglycosylase activity
IMO23_18050	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IMO23_18065	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IMO23_18075	COG3328	transposase activity
IMO23_18080	COG0671	phosphoesterase, PA-phosphatase related
IMO23_18085	COG0861	Integral membrane protein TerC family
IMO23_18095	COG0754	glutathionylspermidine amidase activity
IMO23_18105	COG0402	S-adenosylhomocysteine deaminase activity
IMO23_18120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IMO23_18125	COG1230	cation diffusion facilitator family transporter
IMO23_18140	COG0706	membrane insertase activity
IMO23_18160	COG4716	Myosin-crossreactive antigen
IMO23_18300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IMO23_18320	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IMO23_18495	COG0358	DNA primase activity
IMO23_18555	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IMO23_18610	COG0587	DNA-directed DNA polymerase activity
IMO23_18625	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IMO23_18625	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IMO23_18680	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMO23_18680	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IMO23_18685	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMO23_18745	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IMO23_18805	COG1525	nuclease
IMO23_18870	COG1475	DNA binding
IMO23_19025	COG0741	lytic transglycosylase activity
IMO23_19060	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IMO23_19140	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IMO23_19245	COG2832	Protein of unknown function (DUF454)