locus-tag class description ABTW07_0001 ENOG4105D74 hydrolase ABTW07_0003 ENOG4108821 RND type efflux pump ABTW07_0004 ENOG4108821 RND type efflux pump ABTW07_0005 ENOG4108821 RND type efflux pump ABTW07_0006 ENOG4105C5H ABC transporter ABTW07_0007 ENOG4105DQR SNARE associated Golgi ABTW07_0009 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) ABTW07_0011 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) ABTW07_0013 ENOG4105VG0 50S ribosomal protein l34 ABTW07_0016 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins ABTW07_0019 ENOG4105PGM cation diffusion facilitator family transporter ABTW07_0020 ENOG4105T95 Thiol disulfide interChange protein ABTW07_0022 ENOG4108UGV hypoxanthine phosphoribosyltransferase ABTW07_0023 ENOG4107QUY Guanine deaminase ABTW07_0025 ENOG4106032 Glutathionylspermidine synthase ABTW07_0027 ENOG4105DU1 integral membrane protein, terc ABTW07_0028 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase ABTW07_0030 ENOG4105DFU Cell wall formation (By similarity) ABTW07_0032 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) ABTW07_0033 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit ABTW07_0034 ENOG4105CVE Lytic murein transglycosylase ABTW07_0045 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) ABTW07_0048 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase ABTW07_0050 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) ABTW07_0051 ENOG4105DTN riboflavin biosynthesis protein ribF ABTW07_0053 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) ABTW07_0054 ENOG4108R86 Transcriptional regulator ABTW07_0055 ENOG4108VM9 ABC, transporter ABTW07_0056 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component ABTW07_0057 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) ABTW07_0058 ENOG4105GVF (ABC) transporter ABTW07_0059 ENOG4105GVF (ABC) transporter ABTW07_0060 ENOG4107QZM n-acetylglutamate synthase ABTW07_0063 ENOG4105UBK short-chain dehydrogenase reductase ABTW07_0064 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) ABTW07_0067 ENOG41062JF Transcriptional regulator ABTW07_0072 ENOG4105HSS phospholipase C ABTW07_0074 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase ABTW07_0075 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase ABTW07_0076 ENOG4105CJR Integral membrane protein (MviN ABTW07_0077 ENOG4108V1T peptidylprolyl cis-trans isomerase ABTW07_0078 ENOG4108V1T peptidylprolyl cis-trans isomerase ABTW07_0079 ENOG4105D75 Capsular exopolysaccharide family ABTW07_0081 ENOG4105DAY polysaccharide export protein ABTW07_0082 ENOG4107QQG Dehydrogenase ABTW07_0084 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase ABTW07_0085 ENOG4107SE4 UDP-N-acetylglucosamine 2-epimerase ABTW07_0086 ENOG4105D2T synthase ABTW07_0089 ENOG4105F0R Cytidylyltransferase ABTW07_0090 ENOG4108MY6 biosynthesis protein ABTW07_0091 ENOG4105P7J Transfers sialic acid from the substrate CMP-sialic acid donor to the terminal beta-D-galactosyl-1,4-acetyl-beta-D- glucosamine on the lacto-N-neotetraose branch of the lipooligosaccharide ABTW07_0095 ENOG4105D3Q Sugar transferase ABTW07_0096 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase ABTW07_0097 ENOG4105C6Y Udp-glucose 6-dehydrogenase ABTW07_0099 ENOG4105CMR udp-glucose 4-epimerase ABTW07_0100 ENOG4107QKV phosphomannomutase ABTW07_0101 ENOG4105DAA L-lactate ABTW07_0102 ENOG41073TP transcriptional regulator ABTW07_0104 ENOG4105CXG d-lactate dehydrogenase ABTW07_0105 ENOG4105CGF Aromatic amino acid aminotransferase ABTW07_0106 ENOG4105DRR Transcriptional regulator, GntR family ABTW07_0107 ENOG4105CR4 methylisocitrate lyase ABTW07_0108 ENOG4105BZN citrate synthase ABTW07_0109 ENOG4108I0Z Aconitate hydratase ABTW07_0117 ENOG4105D3G Pseudouridine synthase ABTW07_0122 ENOG4105EW9 transcriptional regulator AsnC family ABTW07_0125 ENOG4105M4H endoribonuclease L-psp ABTW07_0126 ENOG4105C85 amino acid ABTW07_0127 ENOG4105C85 amino acid ABTW07_0129 ENOG4105C26 Dehydrogenase ABTW07_0130 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase ABTW07_0132 ENOG4105C1G acyl-Coa dehydrogenase ABTW07_0133 ENOG4105E39 Enoyl-CoA hydratase ABTW07_0134 ENOG4105E39 Enoyl-CoA hydratase ABTW07_0135 ENOG4105CSH Transporter ABTW07_0140 ENOG4105C1G acyl-Coa dehydrogenase ABTW07_0147 ENOG4107PSF BolA-like protein ABTW07_0149 ENOG4107QJE Chromosome Partitioning Protein ABTW07_0152 ENOG4105DQR SNARE associated Golgi ABTW07_0153 ENOG4108VBZ doxx family ABTW07_0154 ENOG4106MP8 UPF0754 membrane protein ABTW07_0155 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) ABTW07_0159 ENOG4105EUB pirin domain protein ABTW07_0164 ENOG4107R1I NAD-dependent malic enzyme ABTW07_0165 ENOG4105EZR dyp-type peroxidase family protein ABTW07_0167 ENOG4105FAV ABC, transporter ABTW07_0168 ENOG4105FDK ABC transporter ABTW07_0173 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) ABTW07_0181 ENOG4108V06 Glutathione peroxidase ABTW07_0183 ENOG4107RTG Major Facilitator superfamily ABTW07_0184 ENOG4108IND Tetr family transcriptional regulator ABTW07_0187 ENOG4105C79 DNA protecting protein DprA ABTW07_0194 ENOG4105Y7M Transcriptional regulator, TetR family ABTW07_0197 ENOG4105C6T cysteine synthase ABTW07_0199 ENOG4105CS1 NAD(P)H quinone oxidoreductase ABTW07_0203 ENOG4105CCT upf0313 protein ABTW07_0206 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) ABTW07_0209 ENOG4108URH decarboxylase ABTW07_0210 ENOG4105EE5 Membrane protein terC ABTW07_0212 ENOG4105EN6 Membrane ABTW07_0213 ENOG41079KZ Major Facilitator Superfamily ABTW07_0214 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) ABTW07_0215 ENOG4105CEY Amp-dependent synthetase and ligase ABTW07_0218 ENOG4105F0N pyrophosphate phospho-hydrolase ABTW07_0219 ENOG4105EPF Outer membrane porin ABTW07_0221 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) ABTW07_0223 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family ABTW07_0224 ENOG4105C0P Mg chelatase subunit ChlI ABTW07_0269 ENOG4108R0M Aminoglycoside ABTW07_0271 ENOG4105C0P Mg chelatase subunit ChlI ABTW07_0274 ENOG4105BZU Histidine kinase ABTW07_0276 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) ABTW07_0284 ENOG4108K5H permease YjgP YjgQ family protein ABTW07_0285 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) ABTW07_0286 ENOG4105CN1 protease ABTW07_0287 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family ABTW07_0288 ENOG4107TUY Histidine kinase ABTW07_0290 ENOG41061WM D-Alanyl-D-Alanine ABTW07_0292 ENOG4105D6E homoserine dehydrogenase ABTW07_0293 ENOG4105T95 Thiol disulfide interChange protein ABTW07_0294 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) ABTW07_0296 ENOG4105CE1 Ferrous iron transport protein b ABTW07_0299 ENOG4105CNI cell division protein FtsW ABTW07_0300 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) ABTW07_0301 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters ABTW07_0302 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) ABTW07_0307 ENOG4108RNG Permease of the drug metabolite transporter ABTW07_0308 ENOG4105DFG type I secretion outer membrane protein ABTW07_0309 ENOG4108UTW Plays a role in the regulation of phosphate uptake ABTW07_0312 ENOG4108HRK Histidine kinase ABTW07_0313 ENOG4108NEV two component transcriptional regulator, LytTR family ABTW07_0314 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) ABTW07_0319 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS ABTW07_0322 ENOG4105GVR general secretion pathway protein D ABTW07_0323 ENOG4105TV9 FHA Domain-Containing protein ABTW07_0324 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) ABTW07_0327 ENOG4105PM1 preprotein translocase subunit SecE ABTW07_0328 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) ABTW07_0338 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) ABTW07_0339 ENOG4105D3Y Na H antiporter ABTW07_0342 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) ABTW07_0345 ENOG4107ZXU DSBA oxidoreductase ABTW07_0358 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase ABTW07_0359 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) ABTW07_0365 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) ABTW07_0367 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) ABTW07_0370 ENOG4105C2N RNA methyltransferase TrmH family group 3 ABTW07_0372 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) ABTW07_0375 ENOG4107QHF type ii secretion system protein e ABTW07_0377 ENOG4107EJC Preprotein translocase subunit SecG ABTW07_0379 ENOG4105CHV Transcription elongation factor NusA ABTW07_0382 ENOG4105KJM monovalent cation h antiporter subunit g ABTW07_0383 ENOG4105W4C monovalent cation H antiporter subunit F ABTW07_0384 ENOG4105SC1 monovalent cation H antiporter subunit E ABTW07_0385 ENOG4107R4Z monovalent cation h antiporter subunit d ABTW07_0386 ENOG4108ZE9 Monovalent cation H antiporter subunit C ABTW07_0387 ENOG4105D65 subunit l ABTW07_0390 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase ABTW07_0391 ENOG41061H0 Monooxygenase ABTW07_0394 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) ABTW07_0396 ENOG4105CSR polyphosphate kinase 2 ABTW07_0398 ENOG4105DSY exodeoxyribonuclease V, gamma ABTW07_0399 ENOG4107QKA exodeoxyribonuclease V beta ABTW07_0400 ENOG4107QYX exodeoxyribonuclease v alpha ABTW07_0404 ENOG4107QUT magnesium and cobalt transport protein CorA ABTW07_0405 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) ABTW07_0406 ENOG4105DVC DnaJ domain protein ABTW07_0408 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) ABTW07_0409 ENOG4105CKD glutathione-regulated potassium-efflux system protein ABTW07_0410 ENOG4105C25 Primosomal protein n' ABTW07_0411 ENOG4105D7Q type ii secretion system ABTW07_0412 ENOG4108VAU general secretion pathway protein G ABTW07_0414 ENOG4108Z7R Chaperone CsaA ABTW07_0415 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) ABTW07_0416 ENOG4108JU5 Magnesium and cobalt efflux protein ABTW07_0417 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) ABTW07_0418 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase ABTW07_0420 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) ABTW07_0423 ENOG4105C5X domain protein ABTW07_0424 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) ABTW07_0432 ENOG4107T8P acyl-Coa dehydrogenase ABTW07_0434 ENOG4107QI1 Mate efflux family protein ABTW07_0436 ENOG4105CSA Coproporphyrinogen iii oxidase ABTW07_0437 ENOG4105EMU Dehydrogenase ABTW07_0438 ENOG4105CBN LysR family transcriptional regulator ABTW07_0440 ENOG4105C03 ribonuclease ABTW07_0441 ENOG4105EI2 Pseudouridine synthase ABTW07_0442 ENOG4107XGZ Hydrolase ABTW07_0443 ENOG4105D29 Helix-turn-helix type 11 domain protein ABTW07_0446 ENOG4108W5M transcriptional regulator ABTW07_0449 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase ABTW07_0454 ENOG4105DUM transcriptional regulator, lysR family ABTW07_0459 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) ABTW07_0470 ENOG4105CK2 sodium dicarboxylate symporter ABTW07_0472 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase ABTW07_0473 ENOG4105N14 lysine exporter protein LysE YggA ABTW07_0474 ENOG4105C5H ABC transporter ABTW07_0475 ENOG41069P5 Protein slyX homolog ABTW07_0477 ENOG4105KVH Transcriptional regulator ABTW07_0479 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) ABTW07_0482 ENOG4105C4R Atp-dependent dna helicase ABTW07_0483 ENOG4105VFU Rna-binding protein ABTW07_0487 ENOG4105CKD glutathione-regulated potassium-efflux system protein ABTW07_0488 ENOG4105W0E 50S ribosomal protein L33 ABTW07_0489 ENOG4105KDC 50s ribosomal protein l28 ABTW07_0490 ENOG4107RGH Aldehyde dehydrogenase ABTW07_0492 ENOG4105CIY formyltetrahydrofolate deformylase ABTW07_0511 ENOG4105DWV Homoserine O-trans-acetylase ABTW07_0513 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) ABTW07_0515 ENOG4108ESX Receptor ABTW07_0517 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) ABTW07_0521 ENOG4107GFK fumarate ABTW07_0522 ENOG4108DNC Involved in acetate metabolism (By similarity) ABTW07_0523 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) ABTW07_0524 ENOG4105C01 Dihydroxy-acid dehydratase ABTW07_0525 ENOG4108UHU Aldolase ABTW07_0526 ENOG4105C6Z Gluconate ABTW07_0527 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family ABTW07_0528 ENOG4105C26 Dehydrogenase ABTW07_0530 ENOG4106HB6 Alpha beta hydrolase ABTW07_0533 ENOG4105CN1 protease ABTW07_0536 ENOG4105WVQ Fe-S assembly protein IscX ABTW07_0540 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) ABTW07_0544 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) ABTW07_0548 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) ABTW07_0551 ENOG4105CEY Amp-dependent synthetase and ligase ABTW07_0554 ENOG4105C84 Histidine ammonia-lyase ABTW07_0560 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) ABTW07_0562 ENOG4105C2D reductase ABTW07_0563 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) ABTW07_0567 ENOG4105VW4 glutaredoxin 3 ABTW07_0569 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) ABTW07_0570 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) ABTW07_0572 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH ABTW07_0573 ENOG4105ENJ RND efflux system, outer membrane lipoprotein ABTW07_0574 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) ABTW07_0575 ENOG4105DJY efflux transporter, rnd family, mfp subunit ABTW07_0580 ENOG4105C7K acetolactate synthase ABTW07_0581 ENOG4108ZP8 Acetolactate synthase small subunit ABTW07_0583 ENOG4105BZU Histidine kinase ABTW07_0587 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) ABTW07_0590 ENOG4105F8V Hydrolase, tatD family ABTW07_0591 ENOG4107QM5 aconitate hydratase ABTW07_0593 ENOG4105CUZ uba thif-type nad fad binding protein ABTW07_0594 ENOG4107RSM transcriptional regulator ABTW07_0596 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) ABTW07_0599 ENOG4106UX7 integral membrane protein ABTW07_0600 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) ABTW07_0601 ENOG4105W8H transhydrogenase (subunit alpha ABTW07_0602 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) ABTW07_0605 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) ABTW07_0606 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase ABTW07_0607 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase ABTW07_0608 ENOG4105BZU Histidine kinase ABTW07_0609 ENOG4105C6T cysteine synthase ABTW07_0612 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) ABTW07_0614 ENOG4105DXN mazG family ABTW07_0615 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein ABTW07_0616 ENOG4105DJ0 Poly(A) Polymerase ABTW07_0617 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase ABTW07_0621 ENOG41080Z8 PHOSPHOCARRIER protein ABTW07_0622 ENOG4105N42 UPF0307 protein ABTW07_0623 ENOG4105CEY Amp-dependent synthetase and ligase ABTW07_0626 ENOG4105CYM Glutathione S-transferase ABTW07_0627 ENOG4105W39 Membrane ABTW07_0630 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) ABTW07_0635 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) ABTW07_0638 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) ABTW07_0640 ENOG4105C9X ppx gppa phosphatase ABTW07_0642 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) ABTW07_0643 ENOG4105II7 pyrroline-5-carboxylate reductase ABTW07_0644 ENOG4108VIA integral membrane protein ABTW07_0645 ENOG4105C2M dna polymerase I ABTW07_0649 ENOG4107QHF type ii secretion system protein e ABTW07_0650 ENOG4108ZHJ Organic hydroperoxide resistance protein ABTW07_0651 ENOG4105K56 Transcriptional regulator ABTW07_0661 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) ABTW07_0662 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) ABTW07_0663 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) ABTW07_0665 ENOG4105CRQ synthase (Component I) ABTW07_0675 ENOG4108Z0R Transferase ABTW07_0676 ENOG41072GX Peptidase M22 Glycoprotease ABTW07_0681 ENOG4105DJV ribulose-phosphate 3-epimerase ABTW07_0682 ENOG4108HCJ Hydrolase ABTW07_0684 ENOG4105E3B Multicopper oxidase ABTW07_0685 ENOG4105VR0 copper resistance ABTW07_0688 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) ABTW07_0689 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) ABTW07_0690 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) ABTW07_0693 ENOG4105ETT transcriptional Regulator, LysR family ABTW07_0694 ENOG4105C1G acyl-Coa dehydrogenase ABTW07_0695 ENOG4107RGD Major Facilitator superfamily ABTW07_0696 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F ABTW07_0698 ENOG4107EFR Flavocytochrome c ABTW07_0699 ENOG4106P55 Transcriptional regulator ABTW07_0702 ENOG4106P55 Transcriptional regulator ABTW07_0704 ENOG4105CH2 amidohydrolase ABTW07_0708 ENOG4105ETT transcriptional Regulator, LysR family ABTW07_0710 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) ABTW07_0711 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) ABTW07_0715 ENOG4105JAB phenazine biosynthesis protein, phzf family ABTW07_0719 ENOG4105DZG Dehydrogenase ABTW07_0732 ENOG4105EB3 Histidine kinase ABTW07_0734 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) ABTW07_0735 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) ABTW07_0736 ENOG4107EXC regulatoR ABTW07_0737 ENOG4105E0F Histidine kinase ABTW07_0739 ENOG4105BZU Histidine kinase ABTW07_0743 ENOG4105GKE subunit e ABTW07_0744 ENOG4107QIZ NADH dehydrogenase ABTW07_0745 ENOG4108IEH NADH dehydrogenase subunit g ABTW07_0748 ENOG4107UFS subunit j ABTW07_0750 ENOG4105D65 subunit l ABTW07_0751 ENOG4105C8S subunit m ABTW07_0755 ENOG4105DUM transcriptional regulator, lysR family ABTW07_0756 ENOG4105DP0 ferredoxin-NADP reductase ABTW07_0761 ENOG4105CBX hi0933 family ABTW07_0762 ENOG4105K6H D-cysteine desulfhydrase ABTW07_0768 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) ABTW07_0770 ENOG4105D1F ATP-binding protein ABTW07_0780 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) ABTW07_0782 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ABTW07_0785 ENOG4105HF0 Membrane ABTW07_0787 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) ABTW07_0791 ENOG4106UW1 Major Facilitator superfamily ABTW07_0792 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase ABTW07_0793 ENOG4108K4C ec 3.1.3.12 ABTW07_0794 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) ABTW07_0796 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) ABTW07_0797 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) ABTW07_0799 ENOG4105FE9 pseudouridine synthase ABTW07_0800 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) ABTW07_0801 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) ABTW07_0802 ENOG4107RTD sua5 ycio yrdc ywlc family protein ABTW07_0803 ENOG4108BPE -transporting atpase ABTW07_0804 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein ABTW07_0806 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase ABTW07_0807 ENOG4105CHR reductase ABTW07_0809 ENOG4109066 lysm domain bon superfamily protein ABTW07_0810 ENOG4105DWF phosphomethylpyrimidine kinase ABTW07_0812 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) ABTW07_0818 ENOG4105C5T Phosphoribosyl pyrophosphate synthase ABTW07_0820 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) ABTW07_0823 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) ABTW07_0824 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane ABTW07_0825 ENOG4105C34 Pseudouridine synthase ABTW07_0826 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase ABTW07_0830 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding ABTW07_0832 ENOG4105EJC lysr family transcriptional regulator ABTW07_0833 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) ABTW07_0834 ENOG4105C94 Transporter ABTW07_0836 ENOG4105DVW rieske (2Fe-2S) ABTW07_0837 ENOG4105C26 Dehydrogenase ABTW07_0838 ENOG4105E3J oxidoreductase ABTW07_0840 ENOG4105C4K Nad synthetase ABTW07_0842 ENOG4105EUB pirin domain protein ABTW07_0843 ENOG4108YXA Membrane ABTW07_0851 ENOG4105KEG ribosomal-protein-alanine acetyltransferase ABTW07_0853 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) ABTW07_0854 ENOG4105C3M thioredoxin reductase ABTW07_0855 ENOG4105CNU cell division protein FtsK ABTW07_0860 ENOG4107QMS site-determining protein ABTW07_0863 ENOG4106HNH Acyl-transferase ABTW07_0864 ENOG4108ZG0 Ompa motb domain protein ABTW07_0865 ENOG4105C4R Atp-dependent dna helicase ABTW07_0867 ENOG4107QKV phosphomannomutase ABTW07_0870 ENOG4105E7A Glutamine amidotransferase ABTW07_0875 ENOG41090R7 Ferric uptake ABTW07_0876 ENOG4105CZX twitching motility protein ABTW07_0877 ENOG4105CZX twitching motility protein ABTW07_0878 ENOG4105DFA alanine racemase domain protein ABTW07_0879 ENOG4105EYH Exonuclease ABTW07_0880 ENOG4107RH8 nuclease SbcCD subunit D ABTW07_0884 ENOG4105ECP epimerase ABTW07_0885 ENOG4105MWK D-amino acid dehydrogenase, small subunit ABTW07_0886 ENOG4105D52 delta-aminolevulinic acid dehydratase ABTW07_0887 ENOG4108VUY thioesterase Superfamily protein ABTW07_0888 ENOG4105CW7 secretion protein, HlyD family ABTW07_0889 ENOG4105C0R drug resistance transporter emrb qaca subfamily ABTW07_0890 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) ABTW07_0963 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) ABTW07_0975 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) ABTW07_0979 ENOG4105DFP Integrase ABTW07_0995 ENOG4105F8V Hydrolase, tatD family ABTW07_0999 ENOG4105C54 Major Facilitator superfamily ABTW07_1000 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) ABTW07_1002 ENOG4108SF5 RNA Polymerase ABTW07_1008 ENOG4108YNN Heme oxygenase ABTW07_1013 ENOG4105D5Q Arginine ornithine antiporter ABTW07_1014 ENOG4107QK5 Homocysteine s-methyltransferase ABTW07_1019 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) ABTW07_1020 ENOG4105C94 Transporter ABTW07_1021 ENOG4105C94 Transporter ABTW07_1025 ENOG4105CKI cobalamin synthesis protein ABTW07_1027 ENOG4108VWS Yaeq family ABTW07_1029 ENOG4107BJW polysaccharide deacetylase ABTW07_1030 ENOG4105CND Glycosyl transferase, family 2 ABTW07_1032 ENOG4106YT9 Enoyl-CoA hydratase ABTW07_1035 ENOG41069M3 Transcriptional regulator ABTW07_1039 ENOG4105CHR reductase ABTW07_1041 ENOG4108DNI pyridine nucleotide-disulfide oxidoreductase ABTW07_1042 ENOG4105DJB Major Facilitator Superfamily ABTW07_1044 ENOG4108MXF Alpha Beta Hydrolase ABTW07_1045 ENOG4105CHR reductase ABTW07_1048 ENOG4105C7K acetolactate synthase ABTW07_1050 ENOG4105CSH Transporter ABTW07_1051 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) ABTW07_1052 ENOG4105CSV Glutaminase ABTW07_1053 ENOG4108R6W Transcriptional regulator, ARAC family ABTW07_1054 ENOG4105EU0 Major facilitator Superfamily ABTW07_1055 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) ABTW07_1057 ENOG4108PZW LysR family Transcriptional regulator ABTW07_1059 ENOG4105CSP Major Facilitator Superfamily ABTW07_1062 ENOG4105C3R Methionine synthase ABTW07_1063 ENOG4105CJ3 phosphate transporter ABTW07_1067 ENOG4105E6M Sulphatase-modifying factor protein ABTW07_1068 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) ABTW07_1071 ENOG4107RNH Outer membrane receptor FepA ABTW07_1075 ENOG4108UJV acyl-CoA thioesterase i ABTW07_1076 ENOG4108I0Y (ABC) transporter ABTW07_1077 ENOG4105CV6 ABC transporter, permease ABTW07_1078 ENOG4107U91 Rhomboid family ABTW07_1082 ENOG4105C5Q Transcriptional regulator ABTW07_1084 ENOG4107QZF nitrite reductase NADPH large subunit ABTW07_1085 ENOG4105VCQ rubredoxin ABTW07_1089 ENOG4108MRJ ABTW07_1091 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) ABTW07_1094 ENOG4105D4T Citrate transporter ABTW07_1096 ENOG4105C37 (CBS) domain ABTW07_1098 ENOG4107RET Isocitrate lyase ABTW07_1104 ENOG4105CQM Urea amidohydrolase subunit alpha ABTW07_1106 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) ABTW07_1109 ENOG4106H78 methyltransferase ABTW07_1110 ENOG4105CJN penicillin-binding protein ABTW07_1114 ENOG4105CSM endonuclease III ABTW07_1115 ENOG4108R3D Electron transport complex ABTW07_1116 ENOG4105D82 Glutamate dehydrogenase ABTW07_1118 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b ABTW07_1126 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase ABTW07_1192 ENOG4105DR5 peptidase ABTW07_1201 ENOG4105DIJ Phosphoethanolamine transferase ABTW07_1214 ENOG41067SE Tetr family transcriptional regulator ABTW07_1218 ENOG4105CC0 LysR family Transcriptional regulator ABTW07_1220 ENOG4105ETS cytosine purines uracil thiamine allantoin ABTW07_1222 ENOG4108IPJ Membrane ABTW07_1227 ENOG4105GQR Chaperone ABTW07_1228 ENOG4105X0I Fimbrial ABTW07_1232 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) ABTW07_1233 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) ABTW07_1237 ENOG4108HWY Beta-lactamase ABTW07_1250 ENOG4107RAQ aminopeptidase ABTW07_1251 ENOG4105D0A hydroxylase ABTW07_1252 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family ABTW07_1256 ENOG4108ZUB Lysine exporter protein (Lyse ygga) ABTW07_1257 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) ABTW07_1259 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) ABTW07_1261 ENOG4105W4M Transport-associated protein ABTW07_1263 ENOG4105E09 nadh pyrophosphatase ABTW07_1265 ENOG4107RZZ dna polymerase iii epsilon subunit ABTW07_1266 ENOG4105E9H Lytic Murein transglycosylase ABTW07_1266 ENOG4105E9H Lytic Murein transglycosylase ABTW07_1268 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component ABTW07_1269 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component ABTW07_1270 ENOG4108JQ5 ABC transporter ABTW07_1273 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) ABTW07_1277 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase ABTW07_1279 ENOG4108M3P Membrane ABTW07_1280 ENOG4105D01 (LipO)protein ABTW07_1284 ENOG4105CNA YD repeat protein ABTW07_1292 ENOG4105C85 amino acid ABTW07_1294 ENOG4105CUB amino acid ABTW07_1298 ENOG4105C26 Dehydrogenase ABTW07_1303 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) ABTW07_1305 ENOG4105CDU Replicative dna helicase ABTW07_1321 ENOG4105C8Y Acetylornithine aminotransferase ABTW07_1323 ENOG4105C85 amino acid ABTW07_1325 ENOG4105F95 Monooxygenase ABTW07_1332 ENOG4105F95 Monooxygenase ABTW07_1334 ENOG4105C7N Xanthine uracil vitamin C permease ABTW07_1335 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) ABTW07_1336 ENOG4105CPW cytochrome b561 ABTW07_1338 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) ABTW07_1340 ENOG4105CFH Aspartokinase ABTW07_1342 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase ABTW07_1344 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis ABTW07_1347 ENOG4105CPC Aldo Keto reductase ABTW07_1348 ENOG4107RYR Transcriptional regulator, Crp Fnr family ABTW07_1349 ENOG4108UKZ OsmC family ABTW07_1352 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit ABTW07_1358 ENOG4105CD3 dihydroorotase ABTW07_1359 ENOG4108ZG0 Ompa motb domain protein ABTW07_1361 ENOG4108TGY Glutathione S-transferase ABTW07_1362 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) ABTW07_1364 ENOG4108K3A Glutathione S-transferase ABTW07_1366 ENOG4108JU3 Alkyl hydroperoxide reductase ABTW07_1368 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) ABTW07_1370 ENOG4105D3R alkyl hydroperoxide reductase ABTW07_1371 ENOG4105CQ7 ATP-dependent helicase ABTW07_1374 ENOG4105D2S major facilitator superfamily ABTW07_1375 ENOG4105DKK Benzoate ABTW07_1376 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase ABTW07_1377 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein ABTW07_1378 ENOG4108UKV benzoate 1,2-dioxygenase ABTW07_1379 ENOG4105FUY alpha subunit ABTW07_1380 ENOG4108KB2 LysR family Transcriptional regulator ABTW07_1390 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) ABTW07_1395 ENOG410829K Lysine exporter protein (Lyse ygga) ABTW07_1396 ENOG4105VEQ Cold shock protein ABTW07_1398 ENOG4105II7 pyrroline-5-carboxylate reductase ABTW07_1403 ENOG4107YPT transcriptional regulator ABTW07_1408 ENOG4105C2X Arabinose 5-phosphate isomerase ABTW07_1409 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase ABTW07_1411 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA ABTW07_1412 ENOG4108IUZ ABC transporter ABTW07_1413 ENOG4105DFG type I secretion outer membrane protein ABTW07_1421 ENOG4108Z4U Ferredoxin ABTW07_1425 ENOG4107AQZ Membrane ABTW07_1426 ENOG4105BZU Histidine kinase ABTW07_1427 ENOG4105D1S lipid A biosynthesis ABTW07_1429 ENOG4105D2S major facilitator superfamily ABTW07_1433 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) ABTW07_1439 ENOG4105CNA YD repeat protein ABTW07_1442 ENOG4108WAV Transcriptional regulator ABTW07_1443 ENOG4105C5A transporter ABTW07_1447 ENOG4108JIK carboxylase ABTW07_1448 ENOG4107R4J Chloride channel ABTW07_1452 ENOG4105R8C Transcriptional regulator ABTW07_1454 ENOG4105E2A Dehydrogenase ABTW07_1457 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase ABTW07_1458 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF ABTW07_1459 ENOG4105KVH Transcriptional regulator ABTW07_1461 ENOG4105MRR Transcriptional regulator (By similarity) ABTW07_1463 ENOG4108HW3 (ABC) transporter ABTW07_1477 ENOG4105UYK outer membrane protein a ABTW07_1479 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit ABTW07_1485 ENOG4105EMY transcriptional regulator ABTW07_1487 ENOG4107Y2X deaminase ABTW07_1488 ENOG4105DJ2 Major Facilitator Superfamily ABTW07_1491 ENOG4105WPN DNA integration recombination invertion protein ABTW07_1492 ENOG4108Z4X TRANSCRIPTIONal ABTW07_1494 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) ABTW07_1498 ENOG4105MWK D-amino acid dehydrogenase, small subunit ABTW07_1503 ENOG4105CZJ Aldehyde dehydrogenase ABTW07_1504 ENOG4107QTZ amino acid ABTW07_1505 ENOG4105EJQ L-serine dehydratase ABTW07_1506 ENOG4105DXM phenylacetic acid degradation protein ABTW07_1507 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit ABTW07_1508 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit ABTW07_1509 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit ABTW07_1510 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit ABTW07_1511 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) ABTW07_1512 ENOG4105E39 Enoyl-CoA hydratase ABTW07_1513 ENOG4108UKI Enoyl-CoA hydratase ABTW07_1514 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase ABTW07_1515 ENOG4105CHU acetyl-coa acetyltransferase ABTW07_1516 ENOG4105DZS Phenylacetate-CoA ligase ABTW07_1517 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein ABTW07_1519 ENOG4107YAU phenylacetic acid degradation protein ABTW07_1525 ENOG4107VGR Catalase ABTW07_1526 ENOG4105CPW cytochrome b561 ABTW07_1530 ENOG4108MXF Alpha Beta Hydrolase ABTW07_1531 ENOG4105MXW flavin reductase domain protein, FMN-binding ABTW07_1532 ENOG4108M8W Monooxygenase ABTW07_1533 ENOG4105C26 Dehydrogenase ABTW07_1534 ENOG4105ETS cytosine purines uracil thiamine allantoin ABTW07_1536 ENOG4105C26 Dehydrogenase ABTW07_1537 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase ABTW07_1538 ENOG4105HEI LysR family (Transcriptional regulator ABTW07_1540 ENOG4107HP6 Transcriptional regulator ABTW07_1541 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase ABTW07_1543 ENOG4105C4Y ABC transporter ABTW07_1544 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) ABTW07_1545 ENOG4107RCV ABC transporter, permease ABTW07_1547 ENOG4107STF Involved in phosphonate degradation (By similarity) ABTW07_1548 ENOG4108KAZ Involved in phosphonate degradation (By similarity) ABTW07_1549 ENOG4107RGD Major Facilitator superfamily ABTW07_1550 ENOG4105C1G acyl-Coa dehydrogenase ABTW07_1553 ENOG4108UKI Enoyl-CoA hydratase ABTW07_1554 ENOG4105EA8 2-Nitropropane dioxygenase ABTW07_1555 ENOG4105EQ0 Major Facilitator superfamily ABTW07_1557 ENOG4105CHU acetyl-coa acetyltransferase ABTW07_1558 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase ABTW07_1559 ENOG4105CHR reductase ABTW07_1560 ENOG4105E39 Enoyl-CoA hydratase ABTW07_1561 ENOG4105C1G acyl-Coa dehydrogenase ABTW07_1562 ENOG4107RGD Major Facilitator superfamily ABTW07_1563 ENOG4107QP7 CoA-transferase subunit A ABTW07_1564 ENOG4107QNJ CoA-transferase subunit B ABTW07_1566 ENOG4105EQ0 Major Facilitator superfamily ABTW07_1568 ENOG4105CSU acyl-Coa dehydrogenase ABTW07_1571 ENOG4105CC0 LysR family Transcriptional regulator ABTW07_1574 ENOG4105E39 Enoyl-CoA hydratase ABTW07_1575 ENOG4107QX3 carboxylase ABTW07_1576 ENOG4105C1G acyl-Coa dehydrogenase ABTW07_1577 ENOG4105R8C Transcriptional regulator ABTW07_1578 ENOG4105CEY Amp-dependent synthetase and ligase ABTW07_1582 ENOG4105HEI LysR family (Transcriptional regulator ABTW07_1591 ENOG4105CYX Short-chain dehydrogenase reductase Sdr ABTW07_1595 ENOG4105KT5 UmuD protein ABTW07_1597 ENOG4105EW9 transcriptional regulator AsnC family ABTW07_1599 ENOG4105BZU Histidine kinase ABTW07_1600 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase ABTW07_1602 ENOG4105EAD ABC transporter ABTW07_1603 ENOG4108HW4 amino acid AbC transporter ABTW07_1604 ENOG4105CDA abc transporter atp-binding protein ABTW07_1605 ENOG4107RP9 extracellular solute-binding protein, family 3 ABTW07_1606 ENOG4105CT1 (ABC) transporter ABTW07_1607 ENOG4105EXG Transcriptional regulator ABTW07_1609 ENOG4105C9B Cysteine desulfurase ABTW07_1610 ENOG4105ESN nucleotide-binding protein ABTW07_1611 ENOG4105D7W serine acetyltransferase ABTW07_1613 ENOG4105CHR reductase ABTW07_1614 ENOG4105CBN LysR family transcriptional regulator ABTW07_1615 ENOG4105CYM Glutathione S-transferase ABTW07_1616 ENOG4108SHQ Glutathione S-transferase ABTW07_1617 ENOG4105CMU LysR family (Transcriptional regulator ABTW07_1618 ENOG4105VAW lrga family ABTW07_1619 ENOG41067MG lrgb family ABTW07_1623 ENOG4105DXI Major Facilitator superfamily ABTW07_1625 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase ABTW07_1628 ENOG4105PSI phosphoribosyl-dephospho-CoA transferase ABTW07_1629 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase ABTW07_1632 ENOG4108K70 Transcriptional regulator ABTW07_1633 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family ABTW07_1634 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii ABTW07_1635 ENOG4105C4M (Ubiquinol oxidase) subunit I ABTW07_1639 ENOG4105C54 Major Facilitator superfamily ABTW07_1642 ENOG4106FTQ Taurine ABC transporter, periplasmic ABTW07_1643 ENOG4108IY8 ABC, transporter ABTW07_1644 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component ABTW07_1645 ENOG4105E2B Taurine dioxygenase ABTW07_1647 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease ABTW07_1649 ENOG4105CBN LysR family transcriptional regulator ABTW07_1651 ENOG4105CPN adenine deaminase ABTW07_1654 ENOG41082YX Transcriptional regulator, arsr family ABTW07_1655 ENOG4105D6J arsenicaL-resistance protein ABTW07_1656 ENOG4108KB2 LysR family Transcriptional regulator ABTW07_1659 ENOG4108JU3 Alkyl hydroperoxide reductase ABTW07_1664 ENOG4105C0B DNA polymerase III (alpha subunit) ABTW07_1667 ENOG4105CHM Aminotransferase ABTW07_1669 ENOG4108V06 Glutathione peroxidase ABTW07_1670 ENOG4105E7U AraC family transcriptional regulator ABTW07_1676 ENOG4105ZED uncharacterized protein ygaH ABTW07_1677 ENOG4108UMN azlc family ABTW07_1682 ENOG4105C3G gtp-binding protein ABTW07_1683 ENOG4108UMI ABC transporter, permease ABTW07_1684 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) ABTW07_1685 ENOG4105D01 (LipO)protein ABTW07_1686 ENOG4105D01 (LipO)protein ABTW07_1689 ENOG4107T8P acyl-Coa dehydrogenase ABTW07_1692 ENOG4105EAD ABC transporter ABTW07_1693 ENOG4105DRP amino acid AbC transporter ABTW07_1694 ENOG4105CDA abc transporter atp-binding protein ABTW07_1696 ENOG4105EW9 transcriptional regulator AsnC family ABTW07_1710 ENOG4105CDU Replicative dna helicase ABTW07_1726 ENOG41067SE Tetr family transcriptional regulator ABTW07_1730 ENOG4105CC0 LysR family Transcriptional regulator ABTW07_1732 ENOG4105ETS cytosine purines uracil thiamine allantoin ABTW07_1734 ENOG4108IPJ Membrane ABTW07_1739 ENOG4105GQR Chaperone ABTW07_1740 ENOG4105X0I Fimbrial ABTW07_1744 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) ABTW07_1745 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) ABTW07_1749 ENOG4108HWY Beta-lactamase ABTW07_1775 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) ABTW07_1783 ENOG4105CV1 Transketolase (EC 2.2.1.1) ABTW07_1785 ENOG4108YYC ycei family ABTW07_1787 ENOG4108T58 Mg2 transport protein CorA ABTW07_1790 ENOG4105YGK Pfam:UPF0157 ABTW07_1791 ENOG4105C26 Dehydrogenase ABTW07_1792 ENOG4105EW9 transcriptional regulator AsnC family ABTW07_1793 ENOG4105CK7 Sodium proline symporter ABTW07_1794 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) ABTW07_1796 ENOG4108ZX5 transcriptional regulator ABTW07_1798 ENOG4105BZ1 (ABC) transporter ABTW07_1799 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme ABTW07_1800 ENOG4105XPP Protein of unknown function (DUF1275) ABTW07_1802 ENOG41080HT Transcriptional regulator, arsr family ABTW07_1804 ENOG4105EZE Cupin 4 family protein ABTW07_1805 ENOG4108UHJ MAF-like protein ABTW07_1809 ENOG4105D2N Aldolase ABTW07_1810 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) ABTW07_1811 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) ABTW07_1812 ENOG4105EHM Aminoglycoside phosphotransferase ABTW07_1813 ENOG4108S0S Nucleotidyl transferase ABTW07_1815 ENOG4107QJE Chromosome Partitioning Protein ABTW07_1816 ENOG4105FA0 parb-like partition protein ABTW07_1819 ENOG4105BZ1 (ABC) transporter ABTW07_1820 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) ABTW07_1822 ENOG4107QRG dna polymerase iii ABTW07_1824 ENOG4105F8V Hydrolase, tatD family ABTW07_1829 ENOG4108RTD type II secretion system protein K ABTW07_1833 ENOG4108Z6B deaminase ABTW07_1836 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) ABTW07_1837 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) ABTW07_1841 ENOG4107RN6 Monooxygenase ABTW07_1843 ENOG4105D6Z AFG1 family ATPase ABTW07_1844 ENOG4107QP3 malate synthase g ABTW07_1846 ENOG4105SG9 biopolymer transport protein, ExbD ABTW07_1853 ENOG4105DGW oligopeptidase A ABTW07_1855 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component ABTW07_1859 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase ABTW07_1862 ENOG4105K4T epimerase ABTW07_1863 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) ABTW07_1867 ENOG4108JA2 transcriptioN-repair coupling factor ABTW07_1869 ENOG4105F8J Adenylate Guanylate cyclase ABTW07_1870 ENOG4108ZIT Ferredoxin, 2FE-2S ABTW07_1873 ENOG4108Z4V iron-sulfur cluster assembly ABTW07_1874 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins ABTW07_1876 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family ABTW07_1879 ENOG4105K70 DNA-binding protein ABTW07_1880 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) ABTW07_1881 ENOG4105E7U AraC family transcriptional regulator ABTW07_1882 ENOG4105EEF Alkane 1-monooxygenase ABTW07_1883 ENOG4105C1G acyl-Coa dehydrogenase ABTW07_1884 ENOG4105C1G acyl-Coa dehydrogenase ABTW07_1887 ENOG4108Z66 YbaK ebsC protein ABTW07_1891 ENOG4105DUU IucA IucC family protein ABTW07_1892 ENOG4105DJU Siderophore biosynthesis protein ABTW07_1901 ENOG4108YZT Adenosylcobinamide kinase ABTW07_1902 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) ABTW07_1906 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) ABTW07_1907 ENOG4107TSN permease ABTW07_1910 ENOG4105CNM Receptor ABTW07_1911 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) ABTW07_1914 ENOG4105CJ1 ABC, transporter ABTW07_1915 ENOG4107QWP ABC-2 type transporter ABTW07_1916 ENOG4107QWP ABC-2 type transporter ABTW07_1921 ENOG4105K59 histidine triad (HIT) protein ABTW07_1927 ENOG4105F2W methyltransferase ABTW07_1929 ENOG4105C28 cystathionine ABTW07_1932 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) ABTW07_1941 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) ABTW07_1942 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) ABTW07_1944 ENOG4105BZU Histidine kinase ABTW07_1947 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) ABTW07_1948 ENOG4107R0V Pyruvate dehydrogenase ABTW07_1949 ENOG4105CPP Dehydrogenase, E1 component ABTW07_1952 ENOG4105CHR reductase ABTW07_1954 ENOG4105FFC UPF0187 protein ABTW07_1956 ENOG4107QPB Beta-lactamase domain protein ABTW07_1958 ENOG4108VCT Sulfite exporter TauE/SafE ABTW07_1961 ENOG4105UEI Transcriptional Regulator AraC Family ABTW07_1962 ENOG4105KVH Transcriptional regulator ABTW07_1963 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) ABTW07_1965 ENOG4105FDP GntR family transcriptional regulator ABTW07_1968 ENOG4106FTQ Taurine ABC transporter, periplasmic ABTW07_1969 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component ABTW07_1973 ENOG4105CSH Transporter ABTW07_1975 ENOG4108IJ0 Aspartate ammonia-lyase ABTW07_1978 ENOG4107YNJ LysR family Transcriptional regulator ABTW07_1980 ENOG4105CHU acetyl-coa acetyltransferase ABTW07_1981 ENOG4105CRW Short chain fatty acid transporter ABTW07_1982 ENOG4107QNJ CoA-transferase subunit B ABTW07_1984 ENOG4108M0I Transcriptional regulator ABTW07_1986 ENOG4105CY2 Citrate transporter ABTW07_1987 ENOG4105DTD Dehydrogenase ABTW07_1988 ENOG4105CF7 AraC family transcriptional regulator ABTW07_1989 ENOG4105D2S major facilitator superfamily ABTW07_1991 ENOG4105CHR reductase ABTW07_1996 ENOG4105F57 Anthranilate dioxygenase reductase ABTW07_1997 ENOG4108YS2 small subunit ABTW07_1998 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit ABTW07_1999 ENOG4105F4R Transcriptional regulator mode ABTW07_1p008 ENOG4105UGU tonB-dependent Receptor ABTW07_2000 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein ABTW07_2001 ENOG4105E0C molybdate abc transporter ABTW07_2002 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) ABTW07_2003 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase ABTW07_2004 ENOG4105WQI isochorismatase ABTW07_2006 ENOG4107T31 5'-nucleotidase ABTW07_2012 ENOG4108IGT Dipeptidase ABTW07_2016 ENOG4107RZC phospholipase d ABTW07_2026 ENOG4105X0I Fimbrial ABTW07_2029 ENOG4105CJP fad dependent oxidoreductase ABTW07_2034 ENOG4105CT3 Monooxygenase ABTW07_2036 ENOG4105ENJ RND efflux system, outer membrane lipoprotein ABTW07_2037 ENOG4105BZS acriflavin resistance protein ABTW07_2038 ENOG4105C1P efflux transporter, rnd family, mfp subunit ABTW07_2039 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ABTW07_2040 ENOG4105E0F Histidine kinase ABTW07_2041 ENOG4108821 RND type efflux pump ABTW07_2042 ENOG4108R6W Transcriptional regulator, ARAC family ABTW07_2045 ENOG4108BAS reductase ABTW07_2055 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) ABTW07_2063 ENOG4108UAJ Transcriptional regulator ABTW07_2078 ENOG4105C5T Phosphoribosyl pyrophosphate synthase ABTW07_2082 ENOG4105E0A ABC, transporter ABTW07_2083 ENOG4105EHG Permease protein ABTW07_2086 ENOG4105DQ4 alcohol dehydrogenase ABTW07_2089 ENOG4105CF7 AraC family transcriptional regulator ABTW07_2090 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase ABTW07_2092 ENOG4105EXW epimerase dehydratase ABTW07_2093 ENOG4105DDW LysR family Transcriptional regulator ABTW07_2095 ENOG4105C01 Dihydroxy-acid dehydratase ABTW07_2096 ENOG4105CZJ Aldehyde dehydrogenase ABTW07_2099 ENOG4105CW7 secretion protein, HlyD family ABTW07_2106 ENOG4105JSC dimethylmenaquinone methyltransferase ABTW07_2107 ENOG4108JQ1 Dehydrogenase ABTW07_2112 ENOG4106KR7 LysR family Transcriptional regulator ABTW07_2115 ENOG4105FDP GntR family transcriptional regulator ABTW07_2123 ENOG4105D5K Hemolysin activator protein ABTW07_2126 ENOG4105CH2 amidohydrolase ABTW07_2128 ENOG4105CKD glutathione-regulated potassium-efflux system protein ABTW07_2129 ENOG4105D8V Glucose sorbosone dehydrogenase ABTW07_2130 ENOG4105EJC lysr family transcriptional regulator ABTW07_2131 ENOG4105CHJ isochorismatase hydrolase ABTW07_2133 ENOG4107Z3H Transcriptional regulator, TetR family ABTW07_2139 ENOG4105NAE bifunctional deaminase-reductase domain protein ABTW07_2141 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase ABTW07_2142 ENOG4105K56 Transcriptional regulator ABTW07_2146 ENOG4105CH6 catalase ABTW07_2149 ENOG4107RGH Aldehyde dehydrogenase ABTW07_2152 ENOG41062QD Membrane ABTW07_2154 ENOG4108JU7 Transcriptional regulator ABTW07_2155 ENOG4105CHR reductase ABTW07_2156 ENOG4105C1G acyl-Coa dehydrogenase ABTW07_2160 ENOG4105CZJ Aldehyde dehydrogenase ABTW07_2164 ENOG4107EJG GntR family transcriptional regulator ABTW07_2166 ENOG4108KB2 LysR family Transcriptional regulator ABTW07_2167 ENOG4105DTQ mandelate racemase muconate lactonizing ABTW07_2168 ENOG4105NN7 muconolactone delta-isomerase ABTW07_2170 ENOG4107QP7 CoA-transferase subunit A ABTW07_2171 ENOG4107QNJ CoA-transferase subunit B ABTW07_2172 ENOG4105CHU acetyl-coa acetyltransferase ABTW07_2173 ENOG4105CHU acetyl-coa acetyltransferase ABTW07_2174 ENOG4105F2Z 3-oxoadipate enol-lactonase ABTW07_2176 ENOG4105C26 Dehydrogenase ABTW07_2178 ENOG4105F11 amine oxidase ABTW07_2182 ENOG4105CHR reductase ABTW07_2184 ENOG4105FUY alpha subunit ABTW07_2188 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) ABTW07_2190 ENOG4105DNH Major Facilitator ABTW07_2195 ENOG4105C1G acyl-Coa dehydrogenase ABTW07_2196 ENOG4108PTX LysR family Transcriptional regulator ABTW07_2197 ENOG4107HP6 Transcriptional regulator ABTW07_2200 ENOG4105MD1 YeeE YedE family protein ABTW07_2202 ENOG4105DZG Dehydrogenase ABTW07_2203 ENOG4105TW1 Carbohydrate-selective porin OprB ABTW07_2204 ENOG4106JPM 3-dehydroshikimate dehydratase ABTW07_2205 ENOG4105FF2 Type I DHQase ABTW07_2206 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha ABTW07_2207 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta ABTW07_2208 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase ABTW07_2209 ENOG4105D2S major facilitator superfamily ABTW07_2210 ENOG4105F2Z 3-oxoadipate enol-lactonase ABTW07_2211 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase ABTW07_2212 ENOG4105CHU acetyl-coa acetyltransferase ABTW07_2215 ENOG4107QP7 CoA-transferase subunit A ABTW07_2217 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) ABTW07_2218 ENOG4107VMU Membrane ABTW07_2227 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase ABTW07_2230 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) ABTW07_2232 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit ABTW07_2233 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) ABTW07_2239 ENOG4105C7B Threonine dehydratase ABTW07_2241 ENOG4105CZN Potassium uptake protein ABTW07_2242 ENOG4105HDD phospholipase ABTW07_2244 ENOG4105E0K tonB-dependent siderophore receptor ABTW07_2247 ENOG4105PV3 Inner membrane protein yqiJ ABTW07_2248 ENOG4105C4M (Ubiquinol oxidase) subunit I ABTW07_2249 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii ABTW07_2252 ENOG41068P6 UPF0319 protein ABTW07_2254 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ABTW07_2260 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) ABTW07_2261 ENOG4105C8Y Acetylornithine aminotransferase ABTW07_2262 ENOG4105M2J Glutaredoxin ABTW07_2264 ENOG4105CC0 LysR family Transcriptional regulator ABTW07_2265 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) ABTW07_2266 ENOG4105CWM branched-chain amino acid transport system II carrier protein ABTW07_2270 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) ABTW07_2271 ENOG4105DE4 1-phosphofructokinase ABTW07_2272 ENOG4105DM4 PTS System ABTW07_2276 ENOG4105BZU Histidine kinase ABTW07_2278 ENOG4105D8V Glucose sorbosone dehydrogenase ABTW07_2279 ENOG4108RAV Conserved protein ABTW07_2280 ENOG4105CHH sulfate transporter ABTW07_2283 ENOG4105C85 amino acid ABTW07_2285 ENOG4105F7P transcriptional regulator AsnC family ABTW07_2289 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 ABTW07_2290 ENOG4105VEJ Heat shock protein ABTW07_2292 ENOG4105Y3E Modulates RecA activity (By similarity) ABTW07_2294 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) ABTW07_2299 ENOG4105DZP Membrane-associated zinc metalloprotease ABTW07_2301 ENOG4105KNE Phosphatidate cytidylyltransferase ABTW07_2302 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) ABTW07_2306 ENOG4105CUX Signal transduction histidine kinase ABTW07_2307 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family ABTW07_2318 ENOG4105CMR udp-glucose 4-epimerase ABTW07_2319 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) ABTW07_2323 ENOG4105T38 integral membrane protein ABTW07_2324 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family ABTW07_2326 ENOG4105CVM Molybdenum cofactor synthesis domain protein ABTW07_2327 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) ABTW07_2330 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) ABTW07_2334 ENOG4108IFG nitrite reductase, (NAD(P)H) ABTW07_2335 ENOG4107QZF nitrite reductase NADPH large subunit ABTW07_2336 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ABTW07_2340 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein ABTW07_2341 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase ABTW07_2343 ENOG4105D8G Major Facilitator superfamily ABTW07_2358 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) ABTW07_2424 ENOG41083X2 DNA polymerase III, epsilon subunit ABTW07_2438 ENOG4105CBC glutamate synthase ABTW07_2444 ENOG4105C0A alcohol dehydrogenase ABTW07_2446 ENOG4105HSS phospholipase C ABTW07_2448 ENOG4107QMP dna polymerase iii subunits gamma and tau ABTW07_2453 ENOG4105CHR reductase ABTW07_2454 ENOG4105CHU acetyl-coa acetyltransferase ABTW07_2456 ENOG4105C5Q Transcriptional regulator ABTW07_2457 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) ABTW07_2458 ENOG4108NIW Leucine export protein LeuE ABTW07_2459 ENOG4105EW9 transcriptional regulator AsnC family ABTW07_2460 ENOG4105DKK Benzoate ABTW07_2462 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic ABTW07_2466 ENOG41081QV Universal stress protein ABTW07_2467 ENOG4105C5H ABC transporter ABTW07_2470 ENOG4105CNM Receptor ABTW07_2476 ENOG4105CUY Mechanosensitive ion channel ABTW07_2478 ENOG4105R8C Transcriptional regulator ABTW07_2480 ENOG4105EW9 transcriptional regulator AsnC family ABTW07_2481 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) ABTW07_2483 ENOG4105EMU Dehydrogenase ABTW07_2485 ENOG4105CD8 aminopeptidase N ABTW07_2489 ENOG4105F4I Transcriptional regulator ABTW07_2491 ENOG4107QUV Domain protein ABTW07_2492 ENOG4105C0A alcohol dehydrogenase ABTW07_2494 ENOG4107RR1 TRANSCRIPTIONal ABTW07_2496 ENOG4107R55 ethanolamine transporter ABTW07_2497 ENOG4105CPD ethanolamine ammonia-lyase ABTW07_2498 ENOG4107FQ9 ethanolamine ammonia-lyase ABTW07_2499 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) ABTW07_2502 ENOG4105F10 Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity) ABTW07_2503 ENOG4108RCM Nitroreductase ABTW07_2504 ENOG4108TZV Membrane ABTW07_2505 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) ABTW07_2507 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) ABTW07_2508 ENOG4105K8N protein family UPF0079, ATPase ABTW07_2515 ENOG4105DZ2 Transcriptional regulator ABTW07_2518 ENOG4105F27 Major Facilitator ABTW07_2519 ENOG4105EYW Ion transport protein ABTW07_2521 ENOG4107QIJ Aconitate hydratase 2 ABTW07_2524 ENOG4105CFU surface antigen ABTW07_2525 ENOG4107S74 Lysophospholipid transporter LplT ABTW07_2528 ENOG4105CFQ glutamine synthetase ABTW07_2529 ENOG4105EEX Two component transcriptional regulator (Winged helix family ABTW07_2530 ENOG4105C08 Histidine kinase ABTW07_2532 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) ABTW07_2533 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) ABTW07_2537 ENOG4105D06 uba thif-type nad fad binding protein ABTW07_2538 ENOG4108MEJ flavin reductase domain protein ABTW07_2540 ENOG4105C1G acyl-Coa dehydrogenase ABTW07_2543 ENOG4105GVF (ABC) transporter ABTW07_2544 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component ABTW07_2545 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) ABTW07_2548 ENOG4105CC0 LysR family Transcriptional regulator ABTW07_2551 ENOG4105DEN Luciferase family ABTW07_2553 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD ABTW07_2554 ENOG4105CND Glycosyl transferase, family 2 ABTW07_2555 ENOG4107BJW polysaccharide deacetylase ABTW07_2560 ENOG4105E2S oxidase) subunit II ABTW07_2561 ENOG4105BZ9 Cytochrome C oxidase, subunit I ABTW07_2562 ENOG4105CCU oxidase (Subunit III) ABTW07_2563 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) ABTW07_2568 ENOG4105CDU Replicative dna helicase ABTW07_2569 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) ABTW07_2579 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) ABTW07_2580 ENOG4105DC1 bifunctional purine biosynthesis protein purh ABTW07_2581 ENOG4105C12 Phosphoribosylglycinamide synthetase ABTW07_2583 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) ABTW07_2584 ENOG4108UMI ABC transporter, permease ABTW07_2585 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) ABTW07_2586 ENOG4105CK2 sodium dicarboxylate symporter ABTW07_2589 ENOG4105E4C Lytic transglycosylase catalytic ABTW07_2595 ENOG4105F6A helicase ABTW07_2597 ENOG4108HWY Beta-lactamase ABTW07_2598 ENOG4105DY2 Paraquat-inducible protein b ABTW07_2599 ENOG4105F1S paraquat-inducible protein a ABTW07_2602 ENOG4105CEB Aspartate aminotransferase ABTW07_2605 ENOG4105CSH Transporter ABTW07_2615 ENOG4105JXH GntR family transcriptional regulator ABTW07_2617 ENOG4105D6U Sodium Glutamate Symporter ABTW07_2623 ENOG4105H4F exported protein ABTW07_2630 ENOG4105C26 Dehydrogenase ABTW07_2631 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) ABTW07_2632 ENOG4105EVZ LysR family transcriptional regulator ABTW07_2633 ENOG4105D9P serine threonine protein kinase ABTW07_2638 ENOG4105VCC 30S ribosomal protein S21 ABTW07_2639 ENOG4105KTH gatB Yqey ABTW07_2640 ENOG4105ERG peptidase m48, ste24p ABTW07_2641 ENOG4105C5I Dehydrogenase ABTW07_2644 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase ABTW07_2651 ENOG41069NU Nitroreductase ABTW07_2653 ENOG4105C1J atp-dependent rna helicase ABTW07_2654 ENOG4105VEQ Cold shock protein ABTW07_2656 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) ABTW07_2657 ENOG4105M08 Membrane ABTW07_2663 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) ABTW07_2664 ENOG4105CIN aminoacyl-histidine dipeptidase ABTW07_2666 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase ABTW07_2667 ENOG4105CQC Prephenate dehydratase ABTW07_2668 ENOG4105NIV Esterase ABTW07_2669 ENOG4105C1G acyl-Coa dehydrogenase ABTW07_2670 ENOG4105CK2 sodium dicarboxylate symporter ABTW07_2671 ENOG4107QYG anthranilate phosphoribosyltransferase ABTW07_2672 ENOG4105VUT cytoplasmic protein ABTW07_2673 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) ABTW07_2674 ENOG4105BZ4 penicillin-binding protein ABTW07_2676 ENOG4105M6F mutator MutT protein ABTW07_2678 ENOG4105DHQ Histidine kinase ABTW07_2679 ENOG4105XJC Two component transcriptional regulator (Winged helix family ABTW07_2681 ENOG4107QHF type ii secretion system protein e ABTW07_2683 ENOG4108R96 Methyltransferase, YaeB family ABTW07_2684 ENOG4105DP0 ferredoxin-NADP reductase ABTW07_2685 ENOG4105JAB phenazine biosynthesis protein, phzf family ABTW07_2686 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family ABTW07_2687 ENOG4105CFP Peptidase U32 ABTW07_2688 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding ABTW07_2690 ENOG4108JEH abc transporter atp-binding protein ABTW07_2691 ENOG4106YG3 ABC transporter ABTW07_2692 ENOG4105DSP amino acid AbC transporter ABTW07_2693 ENOG4105E89 ABC transporter ABTW07_2695 ENOG4105ENT Efflux transporter rnd family, mfp subunit ABTW07_2697 ENOG4105ENJ RND efflux system, outer membrane lipoprotein ABTW07_2703 ENOG4105DA5 (ABC) transporter ABTW07_2704 ENOG4105E3A (ABC) transporter ABTW07_2707 ENOG4105CNI cell division protein FtsW ABTW07_2708 ENOG4105CVE Lytic murein transglycosylase ABTW07_2715 ENOG4105CE9 30S ribosomal protein S2 ABTW07_2716 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) ABTW07_2718 ENOG4107RNU major facilitator superfamily MFS_1 ABTW07_2720 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) ABTW07_2721 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) ABTW07_2722 ENOG4107QPN acyl-Coa dehydrogenase ABTW07_2725 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) ABTW07_2726 ENOG4105SYT Methylenetetrahydrofolate reductase ABTW07_2727 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) ABTW07_2728 ENOG4105BZU Histidine kinase ABTW07_2729 ENOG4105C6K Malic enzyme ABTW07_2731 ENOG4105C0H protease ABTW07_2732 ENOG4107QNR UPF0135 protein ABTW07_2733 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) ABTW07_2737 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) ABTW07_2739 ENOG4105C5F glutamine synthetase ABTW07_2740 ENOG4105DUX Transporter ABTW07_2742 ENOG4105DFP Integrase ABTW07_2803 ENOG4105DDQ anthranilate synthase ABTW07_2804 ENOG4105CD8 aminopeptidase N ABTW07_2810 ENOG4105C7W Xanthine dehydrogenase ABTW07_2812 ENOG4105EUJ GTP cyclohydrolase i ABTW07_2816 ENOG4105NX3 Membrane ABTW07_2819 ENOG4105E4F Isochorismate synthase ABTW07_2823 ENOG4105BZ1 (ABC) transporter ABTW07_2826 ENOG4105WQI isochorismatase ABTW07_2827 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase ABTW07_2828 ENOG4105C0W non-ribosomal peptide synthetase ABTW07_2832 ENOG4108IPW abc transporter atp-binding protein ABTW07_2835 ENOG4105CEY Amp-dependent synthetase and ligase ABTW07_2838 ENOG4105WWK YheO domain protein ABTW07_2841 ENOG4105C2I pirin domain protein ABTW07_2845 ENOG4105J7D transcriptional regulator ABTW07_2847 ENOG4107WEA mandelate racemase muconate lactonizing ABTW07_2848 ENOG4107QNK )-transporter ABTW07_2849 ENOG41060M8 Pfam:PhdYeFM ABTW07_2855 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) ABTW07_2856 ENOG4107QZF nitrite reductase NADPH large subunit ABTW07_2857 ENOG4105C26 Dehydrogenase ABTW07_2859 ENOG4105C94 Transporter ABTW07_2860 ENOG4105C94 Transporter ABTW07_2861 ENOG4105ETT transcriptional Regulator, LysR family ABTW07_2862 ENOG4105C85 amino acid ABTW07_2863 ENOG4105C26 Dehydrogenase ABTW07_2866 ENOG4108K8K Transcriptional regulator ABTW07_2872 ENOG4105VCD cytoplasmic protein ABTW07_2873 ENOG4105D22 carbon starvation protein ABTW07_2875 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein ABTW07_2879 ENOG4105DHU Bile acid ABTW07_2882 ENOG4105DAN ATP-dependent protease ABTW07_2883 ENOG4105EJC lysr family transcriptional regulator ABTW07_2884 ENOG4108K5P (LipO)protein ABTW07_2888 ENOG4105DZ1 carboxypeptidase ABTW07_2889 ENOG4108Z0R Transferase ABTW07_2893 ENOG4107QTF adenylosuccinate lyase ABTW07_2896 ENOG4105ERU peptidase ABTW07_2897 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) ABTW07_2899 ENOG4105C8U phosphate abc transporter ABTW07_2900 ENOG4105CVA phosphate ABTW07_2901 ENOG4105C85 amino acid ABTW07_2902 ENOG4107RA9 decarboxylase ABTW07_2903 ENOG4105F7P transcriptional regulator AsnC family ABTW07_2905 ENOG4105DY8 decarboxylase ABTW07_2906 ENOG4108JPW Aminotransferase ABTW07_2911 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) ABTW07_2914 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) ABTW07_2915 ENOG4105D3G Pseudouridine synthase ABTW07_2918 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) ABTW07_2924 ENOG4105JAB phenazine biosynthesis protein, phzf family ABTW07_2925 ENOG4108ETY sodium dicarboxylate symporter ABTW07_2926 ENOG4105EGI Transcriptional regulator ABTW07_2927 ENOG4105CBP Major Facilitator ABTW07_2930 ENOG4108R99 pseudouridine synthase ABTW07_2931 ENOG4105E9K Isocitrate dehydrogenase ABTW07_2933 ENOG4105DZ1 carboxypeptidase ABTW07_2934 ENOG4105CEP NADH dehydrogenase ABTW07_2935 ENOG4108YZY peptidylprolyl cis-trans isomerase ABTW07_2936 ENOG4105CVP deoxyribo-dipyrimidine photolyase ABTW07_2939 ENOG4107R8N Glycosyl transferase, family 2 ABTW07_2945 ENOG4105EA8 2-Nitropropane dioxygenase ABTW07_2946 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) ABTW07_2947 ENOG4107QS8 (LipO)protein ABTW07_2954 ENOG4105DTR rard protein ABTW07_2956 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) ABTW07_2958 ENOG4105BZU Histidine kinase ABTW07_2964 ENOG4105EMU Dehydrogenase ABTW07_2965 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase ABTW07_2966 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) ABTW07_2967 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) ABTW07_2969 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) ABTW07_2972 ENOG4105C3F Signal peptidase i ABTW07_2975 ENOG4105C0H protease ABTW07_2976 ENOG4108IYU L-aspartate oxidase ABTW07_2979 ENOG4105HHA aminodeoxychorismate lyase ABTW07_2980 ENOG4105YAZ 4-amino-4-deoxychorismate lyase ABTW07_2981 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein ABTW07_2983 ENOG4108I5D sulfate abc transporter ABTW07_2985 ENOG4108IJ6 ABC transporter ABTW07_2986 ENOG4107R11 Transcriptional regulator ABTW07_2989 ENOG4107VRB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) ABTW07_2990 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) ABTW07_2993 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen ABTW07_2996 ENOG4108UKI Enoyl-CoA hydratase ABTW07_2997 ENOG4105EGD dinuclear metal center protein, YbgI family ABTW07_2998 ENOG4105C2C drug resistance transporter, Bcr CflA ABTW07_2999 ENOG4108ETH Formylglycinamide ribotide synthetase ABTW07_2p009 ENOG4105K5T PilT protein ABTW07_2p016 ENOG4105T95 Thiol disulfide interChange protein ABTW07_2p032 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) ABTW07_2p047 ENOG4105KK6 nuclease ABTW07_2p049 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS ABTW07_2p060 ENOG4105FA0 parb-like partition protein ABTW07_2p064 ENOG4105CDW Resistance protein ABTW07_2p085 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) ABTW07_2p094 ENOG4105F9F transposase ABTW07_3003 ENOG4105CH2 amidohydrolase ABTW07_3004 ENOG4107YD3 Thioesterase ABTW07_3005 ENOG4105E02 MotA TolQ exbB proton channel ABTW07_3006 ENOG4105M8F Biopolymer transport protein exbD tolR ABTW07_3008 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) ABTW07_3009 ENOG4105KCK Peptidoglycan-associated lipoprotein ABTW07_3024 ENOG4105K70 DNA-binding protein ABTW07_3042 ENOG4108Z6H mu-like prophage Flumu protein gp27 ABTW07_3043 ENOG4105CF2 Mu-like prophage FluMu protein GP28 ABTW07_3046 ENOG4105QIB mu-like prophage Flumu protein gp29 ABTW07_3047 ENOG4108QUU Morphogenesis Protein ABTW07_3048 ENOG4107XYH virion morphogenesis protein ABTW07_3051 ENOG4105EFV Major head subunit ABTW07_3070 ENOG4105C02 permease ABTW07_3072 ENOG4108V3E phosphoribosylglycinamide formyltransferase ABTW07_3073 ENOG4107R6F Alpha Beta Hydrolase Fold protein ABTW07_3074 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) ABTW07_3076 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 ABTW07_3077 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) ABTW07_3078 ENOG4105D60 lipoprotein releasing system transmembrane protein ABTW07_3084 ENOG4107KET secretion protein, HlyD family ABTW07_3091 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) ABTW07_3092 ENOG4105C10 Electron transfer flavoprotein ABTW07_3093 ENOG4105BZJ Electron transfer flavoprotein ABTW07_3094 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) ABTW07_3095 ENOG4105N14 lysine exporter protein LysE YggA ABTW07_3097 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) ABTW07_3099 ENOG4105C85 amino acid ABTW07_3100 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) ABTW07_3102 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) ABTW07_3105 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) ABTW07_3106 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit ABTW07_3107 ENOG4105BZW Glycerate kinase ABTW07_3115 ENOG4105CEY Amp-dependent synthetase and ligase ABTW07_3117 ENOG4108RRZ Transcription elongation factor GreB ABTW07_3121 ENOG4105E4C Lytic transglycosylase catalytic ABTW07_3124 ENOG4105BZS acriflavin resistance protein ABTW07_3125 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase ABTW07_3127 ENOG41080IJ Diacylglycerol kinase ABTW07_3131 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) ABTW07_3134 ENOG4105C6V Glycerol-3-phosphate dehydrogenase ABTW07_3135 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) ABTW07_3136 ENOG4105CSH Transporter ABTW07_3143 ENOG4105EEI dihydropteroate synthase ABTW07_3144 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) ABTW07_3146 ENOG4105HBR Rna-binding protein ABTW07_3149 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain ABTW07_3150 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain ABTW07_3153 ENOG41080TK Universal stress protein ABTW07_3156 ENOG4105PNM synthesis protein ABTW07_3162 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) ABTW07_3170 ENOG4105EEQ Na H antiporter ABTW07_3171 ENOG4105CGZ zinc metallopeptidase ABTW07_3172 ENOG4105CKW Inner membrane protein yedI ABTW07_3174 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha ABTW07_3176 ENOG4107QN2 dihydrolipoyl dehydrogenase ABTW07_3177 ENOG4105C7S Dehydrogenase ABTW07_3178 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 ABTW07_3179 ENOG4105E33 succinate dehydrogenase ABTW07_3181 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein ABTW07_3182 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit ABTW07_3187 ENOG4105F9F transposase ABTW07_3190 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) ABTW07_3191 ENOG41084BA UPF0250 protein ABTW07_3192 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) ABTW07_3195 ENOG4105CUB amino acid ABTW07_3197 ENOG4105KVH Transcriptional regulator ABTW07_3198 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) ABTW07_3199 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) ABTW07_3202 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) ABTW07_3207 ENOG410841Q phosphoesterase PA-phosphatase related protein ABTW07_3208 ENOG4105C1P efflux transporter, rnd family, mfp subunit ABTW07_3209 ENOG4105BZS acriflavin resistance protein ABTW07_3210 ENOG4105ENJ RND efflux system, outer membrane lipoprotein ABTW07_3211 ENOG4105K8R UPF0145 protein ABTW07_3212 ENOG4105K8R UPF0145 protein ABTW07_3216 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) ABTW07_3220 ENOG4108M0I Transcriptional regulator ABTW07_3223 ENOG4105DHQ Histidine kinase ABTW07_3224 ENOG4105XJC Two component transcriptional regulator (Winged helix family ABTW07_3229 ENOG4105D78 K07001 NTE family protein ABTW07_3232 ENOG4105MSB protein, conserved in bacteria ABTW07_3233 ENOG4105CTB Polyprenyl synthetase ABTW07_3234 ENOG4105C7F AcnD-accessory protein PrpF ABTW07_3235 ENOG4105C85 amino acid ABTW07_3238 ENOG4105CF7 AraC family transcriptional regulator ABTW07_3243 ENOG4108X0B nad(p)h dehydrogenase (quinone) ABTW07_3245 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein ABTW07_3247 ENOG4105D8T Acyltransferase ABTW07_3249 ENOG4105C03 ribonuclease ABTW07_3250 ENOG4108Z03 MAF-like protein ABTW07_3252 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) ABTW07_3253 ENOG4105DFF Rod shape-determining protein mreb ABTW07_3254 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) ABTW07_3256 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) ABTW07_3263 ENOG4105C7B Threonine dehydratase ABTW07_3264 ENOG4105D78 K07001 NTE family protein ABTW07_3265 ENOG4105BZG amino acid carrier protein ABTW07_3269 ENOG4105C2C drug resistance transporter, Bcr CflA ABTW07_3270 ENOG4105EM2 membrane ABTW07_3272 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) ABTW07_3274 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein ABTW07_3275 ENOG4105WD1 Membrane ABTW07_3279 ENOG4105CBS Chea signal transduction histidine kinase ABTW07_3280 ENOG4105C8Q Methyl-accepting chemotaxis ABTW07_3281 ENOG4108ZGA chew protein ABTW07_3282 ENOG4105M3Z response regulator ABTW07_3283 ENOG4108UNF response regulator ABTW07_3288 ENOG4105KWI UPF0339 protein ABTW07_3289 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA ABTW07_3290 ENOG4105K78 MarR family Transcriptional regulator ABTW07_3292 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) ABTW07_3293 ENOG4105T95 Thiol disulfide interChange protein ABTW07_3295 ENOG4108N2Y auxin Efflux ABTW07_3296 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase ABTW07_3297 ENOG4105CHB tonB-dependent Receptor ABTW07_3298 ENOG4108VX5 3-methyladenine DNA glycosylase ABTW07_3300 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) ABTW07_3304 ENOG4105C2W permease ABTW07_3306 ENOG4108IQI permease ABTW07_3307 ENOG4105E0Y RtcB Protein ABTW07_3309 ENOG4108WHA ompa motb domain protein ABTW07_3311 ENOG4105CHU acetyl-coa acetyltransferase ABTW07_3313 ENOG410814C multidrug resistance protein ABTW07_3315 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) ABTW07_3316 ENOG4105DZG Dehydrogenase ABTW07_3317 ENOG4105TW1 Carbohydrate-selective porin OprB ABTW07_3319 ENOG4108R6W Transcriptional regulator, ARAC family ABTW07_3320 ENOG4105CHU acetyl-coa acetyltransferase ABTW07_3327 ENOG4108UT2 hemolysin iii ABTW07_3328 ENOG4105CSH Transporter ABTW07_3331 ENOG4105D3R alkyl hydroperoxide reductase ABTW07_3335 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase ABTW07_3342 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) ABTW07_3345 ENOG4108WBT adenosyltransferase ABTW07_3349 ENOG4105CNG UPF0061 protein ABTW07_3350 ENOG4105E3W Two component transcriptional regulator (Winged helix family ABTW07_3351 ENOG4105EB3 Histidine kinase ABTW07_3353 ENOG4105CSU acyl-Coa dehydrogenase ABTW07_3354 ENOG4105CSU acyl-Coa dehydrogenase ABTW07_3355 ENOG4108R4R Iron-regulated virulence regulatory protein ABTW07_3356 ENOG4108K3A Glutathione S-transferase ABTW07_3357 ENOG4108VY7 phosphate-starvation-inducible protein PsiE ABTW07_3361 ENOG4105UGU tonB-dependent Receptor ABTW07_3369 ENOG4108PQP glycosyl transferase group 1 ABTW07_3371 ENOG4107BJW polysaccharide deacetylase ABTW07_3374 ENOG4105CM2 brancheD-chain amino acid aminotransferase ABTW07_3375 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) ABTW07_3376 ENOG4105BZU Histidine kinase ABTW07_3381 ENOG4105VIE preprotein translocase, subunit YajC ABTW07_3382 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) ABTW07_3383 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) ABTW07_3384 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase ABTW07_3386 ENOG4105FFC UPF0187 protein ABTW07_3387 ENOG4105DB7 PHP domain protein ABTW07_3389 ENOG4105K9H YciI-like protein ABTW07_3395 ENOG4105NAU thioesterase Superfamily protein ABTW07_3397 ENOG4107U2T alpha beta ABTW07_3398 ENOG4107QPB Beta-lactamase domain protein ABTW07_3400 ENOG4107QN2 dihydrolipoyl dehydrogenase ABTW07_3403 ENOG4108KHX Diguanylate cyclase ABTW07_3404 ENOG4105UYK outer membrane protein a ABTW07_3406 ENOG4107RZC phospholipase d ABTW07_3408 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) ABTW07_3412 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) ABTW07_3413 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) ABTW07_3414 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) ABTW07_3416 ENOG4108UJD 30S ribosomal protein S9 ABTW07_3417 ENOG4107MKT Stringent starvation protein a ABTW07_3418 ENOG4105KB2 stringent starvation protein b ABTW07_3422 ENOG4105C1G acyl-Coa dehydrogenase ABTW07_3423 ENOG4107QX3 carboxylase ABTW07_3426 ENOG4108RZE Tetr family transcriptional regulator ABTW07_3427 ENOG4105C1G acyl-Coa dehydrogenase ABTW07_3432 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase ABTW07_3433 ENOG4105D6S protein involved in catabolism of external DNA ABTW07_3439 ENOG4105E4C Lytic transglycosylase catalytic ABTW07_3441 ENOG4105C9A Phoh family ABTW07_3447 ENOG4105CS1 NAD(P)H quinone oxidoreductase ABTW07_3448 ENOG4107S2Z UPF0761 membrane protein ABTW07_3450 ENOG4108K2B transcriptional regulator ABTW07_3451 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase ABTW07_3456 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) ABTW07_3457 ENOG4105DGW oligopeptidase A ABTW07_3458 ENOG4105VKU nucleicacid-binding protein ABTW07_3465 ENOG4105C1G acyl-Coa dehydrogenase ABTW07_3470 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) ABTW07_3472 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) ABTW07_3494 ENOG41089BK Glutamine amido-transferase ABTW07_3495 ENOG4105C28 cystathionine ABTW07_3496 ENOG4105D7A ATP-binding protein ABTW07_3498 ENOG4105KPV Transcriptional regulator ABTW07_3501 ENOG4105CK2 sodium dicarboxylate symporter ABTW07_3502 ENOG4105C29 acyl-CoA thioesterase ABTW07_3506 ENOG4105CB5 ATP-dependent DNA helicase recG ABTW07_3507 ENOG4105MJ2 Competence protein ABTW07_3509 ENOG4108URH decarboxylase ABTW07_3510 ENOG4105D7N magnesium and cobalt transport protein CorA ABTW07_3512 ENOG4105E3I toluene tolerance ABTW07_3514 ENOG4105CY3 ABC transporter, permease ABTW07_3515 ENOG4105DHJ ABC, transporter ABTW07_3517 ENOG4105C1J atp-dependent rna helicase ABTW07_3518 ENOG4105ECY inositol monophosphatase ABTW07_3521 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) ABTW07_3524 ENOG4105CSU acyl-Coa dehydrogenase ABTW07_3526 ENOG41067S9 phage shock protein C, PspC ABTW07_3527 ENOG4105W87 Cbs domain ABTW07_3539 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin ABTW07_3544 ENOG4105C26 Dehydrogenase ABTW07_3546 ENOG4105C8Y Acetylornithine aminotransferase ABTW07_3546 ENOG4105C8Y Acetylornithine aminotransferase ABTW07_3547 ENOG4105D82 Glutamate dehydrogenase ABTW07_3549 ENOG4108IQI permease ABTW07_3555 ENOG4107SKI cobyrinic Acid a,c-diamide synthase ABTW07_3556 ENOG4105IPI Membrane ABTW07_3557 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) ABTW07_3558 ENOG4105EM2 membrane ABTW07_3559 ENOG4107QF7 multi-drug ABTW07_3561 ENOG4105NF4 modulator of drug activity ABTW07_3562 ENOG4105VRH Antibiotic biosynthesis monooxygenase ABTW07_3564 ENOG4105CQB FAD linked oxidase domain protein ABTW07_3565 ENOG4108JQ1 Dehydrogenase ABTW07_3570 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) ABTW07_3571 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) ABTW07_3572 ENOG4107IFA Lipase (EC 3.1.1.3) ABTW07_3575 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) ABTW07_3585 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) ABTW07_3587 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) ABTW07_3588 ENOG4105KME endoribonuclease L-psp ABTW07_3590 ENOG4108UQY Iron-storage protein ABTW07_3591 ENOG4108YSG O-Antigen polymerase ABTW07_3595 ENOG4105HA9 of methanol dehydrogenase type ABTW07_3596 ENOG4108V0P LemA family ABTW07_3598 ENOG4105BZ8 glutamate synthase ABTW07_3599 ENOG4105CBC glutamate synthase ABTW07_3603 ENOG4105E4G Type IV pilus ABTW07_3608 ENOG4108JQC penicillin-binding protein 1A ABTW07_3609 ENOG4105DHI Methyltransferase ABTW07_3612 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) ABTW07_3613 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) ABTW07_3614 ENOG4105CJN penicillin-binding protein ABTW07_3617 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein ABTW07_3620 ENOG4108IQI permease ABTW07_3634 ENOG4105C5H ABC transporter ABTW07_3636 ENOG4105PDP Short chain dehydrogenase ABTW07_3637 ENOG4105CHH sulfate transporter ABTW07_3639 ENOG4105DPZ Two component transcriptional regulator (Winged helix family ABTW07_3640 ENOG4105E0F Histidine kinase ABTW07_3641 ENOG4105CYC Transferase ABTW07_3645 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) ABTW07_3651 ENOG41061CK Antibiotic biosynthesis monooxygenase ABTW07_3654 ENOG4105CUV Homoserine Kinase ABTW07_3666 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein ABTW07_3667 ENOG4105KVH Transcriptional regulator ABTW07_3671 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) ABTW07_3672 ENOG4105CPC Aldo Keto reductase ABTW07_3676 ENOG4107RSM transcriptional regulator ABTW07_3677 ENOG4105D94 Major Facilitator Superfamily ABTW07_3681 ENOG4105EUB pirin domain protein ABTW07_3682 ENOG4105CHJ isochorismatase hydrolase ABTW07_3684 ENOG4105C26 Dehydrogenase ABTW07_3685 ENOG4108JPW Aminotransferase ABTW07_3687 ENOG4105C85 amino acid ABTW07_3689 ENOG4108UMN azlc family ABTW07_3691 ENOG4108UUM single-stranded DNA-binding protein ABTW07_3692 ENOG4107RDB Major Facilitator ABTW07_3694 ENOG4105DWF phosphomethylpyrimidine kinase ABTW07_3695 ENOG4105RA2 Membrane ABTW07_3697 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein ABTW07_3698 ENOG4108WUH Transcriptional regulator, TetR family ABTW07_3699 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) ABTW07_3701 ENOG4105BZU Histidine kinase ABTW07_3703 ENOG4105C94 Transporter ABTW07_3705 ENOG4107QN1 sodium solute ABTW07_3706 ENOG41062QD Membrane ABTW07_3707 ENOG4105BZU Histidine kinase ABTW07_3710 ENOG4108UZX fmn reductase ABTW07_3711 ENOG4105FBW Monooxygenase ABTW07_3713 ENOG4108W2Y isochorismatase ABTW07_3714 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) ABTW07_3716 ENOG4105D64 Mechanosensitive ion channel ABTW07_3718 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase ABTW07_3719 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase ABTW07_3721 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) ABTW07_3723 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) ABTW07_3726 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) ABTW07_3729 ENOG4105E0K tonB-dependent siderophore receptor ABTW07_3732 ENOG4107QSN dihydrolipoamide acetyltransferase ABTW07_3733 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) ABTW07_3734 ENOG41063SB peptidase ABTW07_3737 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) ABTW07_3738 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) ABTW07_3739 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) ABTW07_3743 ENOG4105D7Z glutathione synthase ABTW07_3747 ENOG4105CGK Exodeoxyribonuclease III ABTW07_3748 ENOG4105KUZ arsenate reductase ABTW07_3751 ENOG4105BZU Histidine kinase ABTW07_3752 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) ABTW07_3758 ENOG41084YZ Hydrolase ABTW07_3761 ENOG41061H0 Monooxygenase ABTW07_3763 ENOG4108Z2U ureidoglycolate hydrolase ABTW07_3764 ENOG4105EWI Short-chain dehydrogenase reductase Sdr ABTW07_3765 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) ABTW07_3766 ENOG4105IPS esterase ABTW07_3771 ENOG4105CS6 Rhs element vgr protein ABTW07_3773 ENOG4105D9M gamma-glutamylcysteine synthetase ABTW07_3776 ENOG4106BRA Membrane ABTW07_3777 ENOG4105CHM Aminotransferase ABTW07_3778 ENOG4107QJQ Mate efflux family protein ABTW07_3781 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ABTW07_3782 ENOG4105BZU Histidine kinase ABTW07_3788 ENOG4105KHC sulfurtransferase ABTW07_3793 ENOG4105EAC phosphoserine phosphatase ABTW07_3795 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) ABTW07_3798 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) ABTW07_3799 ENOG4108ZAI phosphatidylglycerophosphatase a ABTW07_3801 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) ABTW07_3802 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) ABTW07_3805 ENOG41088SP formiminoglutamate hydrolase ABTW07_3807 ENOG4105C85 amino acid ABTW07_3810 ENOG41090B9 response to stress ABTW07_3811 ENOG4105CZE histidine utilization repressor ABTW07_3813 ENOG4105CKI cobalamin synthesis protein ABTW07_3815 ENOG4105C85 amino acid ABTW07_3817 ENOG4108RXX maleylacetoacetate isomerase ABTW07_3821 ENOG4105EWC Purine nucleoside phosphorylase ABTW07_3822 ENOG4107QI1 Mate efflux family protein ABTW07_3823 ENOG4105C09 Bile acid ABTW07_3824 ENOG4108RWI nicotinamidase ABTW07_3825 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) ABTW07_3829 ENOG4105S64 Formate nitrite transporter ABTW07_3830 ENOG4105D1H recombination factor protein RarA ABTW07_3832 ENOG4108ZZ3 UPF0260 protein ABTW07_3836 ENOG4105CEN a g-specific adenine glycosylase ABTW07_3839 ENOG4108R3E Dna-3-methyladenine glycosylase i ABTW07_3840 ENOG4105DQ4 alcohol dehydrogenase ABTW07_3843 ENOG4105HEI LysR family (Transcriptional regulator ABTW07_3844 ENOG4105CV8 reductase ABTW07_3845 ENOG4105F27 Major Facilitator ABTW07_3852 ENOG4105DJY efflux transporter, rnd family, mfp subunit ABTW07_3853 ENOG4108IG5 Transcriptional regulator ABTW07_3855 ENOG4105C2W permease ABTW07_3856 ENOG4108W5M transcriptional regulator ABTW07_3861 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B ABTW07_3862 ENOG4105C8J )-transporter ABTW07_3865 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) ABTW07_3866 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) ABTW07_3869 ENOG4105CHH sulfate transporter ABTW07_3870 ENOG4105D13 transposase ABTW07_3871 ENOG4108C33 Resolvase ABTW07_3910 ENOG4105CHH sulfate transporter ABTW07_3915 ENOG4107QNJ CoA-transferase subunit B