locus-tag class description EA674_000010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) EA674_000020 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EA674_000030 ENOG4105DQR SNARE associated Golgi EA674_000035 ENOG4105C5H ABC transporter EA674_000040 ENOG4108821 RND type efflux pump EA674_000045 ENOG4108821 RND type efflux pump EA674_000050 ENOG4108821 RND type efflux pump EA674_000060 ENOG4105D74 hydrolase EA674_000065 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) EA674_000070 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) EA674_000115 ENOG4105C8J )-transporter EA674_000125 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B EA674_000155 ENOG4105C2W permease EA674_000165 ENOG4108IG5 Transcriptional regulator EA674_000170 ENOG4105DJY efflux transporter, rnd family, mfp subunit EA674_000205 ENOG4105F27 Major Facilitator EA674_000210 ENOG4105CV8 reductase EA674_000215 ENOG4105HEI LysR family (Transcriptional regulator EA674_000235 ENOG4105DQ4 alcohol dehydrogenase EA674_000240 ENOG4108R3E Dna-3-methyladenine glycosylase i EA674_000255 ENOG4105CEN a g-specific adenine glycosylase EA674_000275 ENOG4108ZZ3 UPF0260 protein EA674_000285 ENOG4105D1H recombination factor protein RarA EA674_000290 ENOG4105S64 Formate nitrite transporter EA674_000310 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EA674_000315 ENOG4108RWI nicotinamidase EA674_000320 ENOG4105C09 Bile acid EA674_000325 ENOG4107QI1 Mate efflux family protein EA674_000330 ENOG4105EWC Purine nucleoside phosphorylase EA674_000350 ENOG4108RXX maleylacetoacetate isomerase EA674_000360 ENOG4105C85 amino acid EA674_000370 ENOG4105CKI cobalamin synthesis protein EA674_000380 ENOG4105CZE histidine utilization repressor EA674_000385 ENOG41090B9 response to stress EA674_000400 ENOG4105C85 amino acid EA674_000410 ENOG41088SP formiminoglutamate hydrolase EA674_000430 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) EA674_000435 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) EA674_000445 ENOG4108ZAI phosphatidylglycerophosphatase a EA674_000450 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) EA674_000465 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) EA674_000505 ENOG4105KHC sulfurtransferase EA674_000535 ENOG4105BZU Histidine kinase EA674_000540 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EA674_000555 ENOG4107QJQ Mate efflux family protein EA674_000560 ENOG4105CHM Aminotransferase EA674_000565 ENOG4106BRA Membrane EA674_000580 ENOG4105D9M gamma-glutamylcysteine synthetase EA674_000590 ENOG4105CS6 Rhs element vgr protein EA674_000615 ENOG4105IPS esterase EA674_000620 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EA674_000625 ENOG4105EWI Short-chain dehydrogenase reductase Sdr EA674_000630 ENOG4108Z2U ureidoglycolate hydrolase EA674_000640 ENOG41061H0 Monooxygenase EA674_000655 ENOG41084YZ Hydrolase EA674_000685 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) EA674_000690 ENOG4105BZU Histidine kinase EA674_000705 ENOG4105KUZ arsenate reductase EA674_000710 ENOG4105CGK Exodeoxyribonuclease III EA674_000730 ENOG4105D7Z glutathione synthase EA674_000750 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) EA674_000755 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) EA674_000760 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) EA674_000775 ENOG41063SB peptidase EA674_000780 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) EA674_000785 ENOG4107QSN dihydrolipoamide acetyltransferase EA674_000800 ENOG4105E0K tonB-dependent siderophore receptor EA674_000815 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) EA674_000830 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) EA674_000850 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EA674_000855 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase EA674_000865 ENOG4105D64 Mechanosensitive ion channel EA674_000875 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) EA674_000880 ENOG4108W2Y isochorismatase EA674_000890 ENOG4105D5G Transposase EA674_000895 ENOG4105FBW Monooxygenase EA674_000900 ENOG4108UZX fmn reductase EA674_000915 ENOG4105BZU Histidine kinase EA674_000920 ENOG41062QD Membrane EA674_000925 ENOG4107QN1 sodium solute EA674_000935 ENOG4105C94 Transporter EA674_000945 ENOG4105BZU Histidine kinase EA674_000955 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) EA674_000960 ENOG4108WUH Transcriptional regulator, TetR family EA674_000965 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein EA674_000975 ENOG4105RA2 Membrane EA674_000980 ENOG4105DWF phosphomethylpyrimidine kinase EA674_000990 ENOG4107RDB Major Facilitator EA674_000995 ENOG4108UUM single-stranded DNA-binding protein EA674_001005 ENOG4108UMN azlc family EA674_001015 ENOG4105C85 amino acid EA674_001025 ENOG4108JPW Aminotransferase EA674_001030 ENOG4105C26 Dehydrogenase EA674_001040 ENOG4105CHJ isochorismatase hydrolase EA674_001045 ENOG4105EUB pirin domain protein EA674_001070 ENOG4105D94 Major Facilitator Superfamily EA674_001075 ENOG4106NZI LysR family Transcriptional regulator EA674_001095 ENOG4105CPC Aldo Keto reductase EA674_001100 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) EA674_001130 ENOG4105KVH Transcriptional regulator EA674_001140 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein EA674_001205 ENOG4105CUV Homoserine Kinase EA674_001220 ENOG41061CK Antibiotic biosynthesis monooxygenase EA674_001250 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) EA674_001280 ENOG4105CYC Transferase EA674_001290 ENOG4105E0F Histidine kinase EA674_001295 ENOG4105DPZ Two component transcriptional regulator (Winged helix family EA674_001305 ENOG4105CHH sulfate transporter EA674_001310 ENOG4105PDP Short chain dehydrogenase EA674_001320 ENOG4105C5H ABC transporter EA674_001405 ENOG4108IQI permease EA674_001430 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein EA674_001445 ENOG4105CJN penicillin-binding protein EA674_001450 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) EA674_001455 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) EA674_001470 ENOG4105DHI Methyltransferase EA674_001475 ENOG4108JQC penicillin-binding protein 1A EA674_001500 ENOG4105E4G Type IV pilus EA674_001520 ENOG4105CBC glutamate synthase EA674_001525 ENOG4105BZ8 glutamate synthase EA674_001535 ENOG4108V0P LemA family EA674_001540 ENOG4105HA9 of methanol dehydrogenase type EA674_001555 ENOG4108YSG O-Antigen polymerase EA674_001560 ENOG4108UQY Iron-storage protein EA674_001570 ENOG4105KME endoribonuclease L-psp EA674_001575 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) EA674_001590 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) EA674_001640 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) EA674_001655 ENOG4107IFA Lipase (EC 3.1.1.3) EA674_001660 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) EA674_001665 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) EA674_001690 ENOG4108JQ1 Dehydrogenase EA674_001695 ENOG4105CQB FAD linked oxidase domain protein EA674_001705 ENOG4105VRH Antibiotic biosynthesis monooxygenase EA674_001710 ENOG4105NF4 modulator of drug activity EA674_001720 ENOG4107QF7 multi-drug EA674_001725 ENOG4105EM2 membrane EA674_001730 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) EA674_001735 ENOG4105IPI Membrane EA674_001740 ENOG4107SKI cobyrinic Acid a,c-diamide synthase EA674_001770 ENOG4108IQI permease EA674_001775 ENOG4105D82 Glutamate dehydrogenase EA674_001780 ENOG4105C8Y Acetylornithine aminotransferase EA674_001790 ENOG4105C26 Dehydrogenase EA674_001815 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin EA674_001875 ENOG4105W87 Cbs domain EA674_001880 ENOG41067S9 phage shock protein C, PspC EA674_001890 ENOG4105CSU acyl-Coa dehydrogenase EA674_001905 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) EA674_001920 ENOG4105ECY inositol monophosphatase EA674_001925 ENOG4105C1J atp-dependent rna helicase EA674_001935 ENOG4105DHJ ABC, transporter EA674_001940 ENOG4105CY3 ABC transporter, permease EA674_001950 ENOG4105E3I toluene tolerance EA674_001960 ENOG4105D7N magnesium and cobalt transport protein CorA EA674_001965 ENOG4108URH decarboxylase EA674_001975 ENOG4105MJ2 Competence protein EA674_001980 ENOG4105CB5 ATP-dependent DNA helicase recG EA674_002000 ENOG4105C29 acyl-CoA thioesterase EA674_002005 ENOG4105CK2 sodium dicarboxylate symporter EA674_002020 ENOG4105KPV Transcriptional regulator EA674_002030 ENOG4105D7A ATP-binding protein EA674_002035 ENOG4105C28 cystathionine EA674_002040 ENOG41089BK Glutamine amido-transferase EA674_002150 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) EA674_002155 ENOG41067V7 50S ribosomal protein L36 EA674_002165 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) EA674_002190 ENOG4105C1G acyl-Coa dehydrogenase EA674_002225 ENOG4105VKU nucleicacid-binding protein EA674_002230 ENOG4105DGW oligopeptidase A EA674_002235 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) EA674_002280 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase EA674_002285 ENOG4108K2B transcriptional regulator EA674_002295 ENOG4107S2Z UPF0761 membrane protein EA674_002300 ENOG4105CS1 NAD(P)H quinone oxidoreductase EA674_002330 ENOG4105C9A Phoh family EA674_002340 ENOG4105E4C Lytic transglycosylase catalytic EA674_002370 ENOG4105D6S protein involved in catabolism of external DNA EA674_002375 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase EA674_002420 ENOG4105C1G acyl-Coa dehydrogenase EA674_002425 ENOG4108RZE Tetr family transcriptional regulator EA674_002440 ENOG4107QX3 carboxylase EA674_002445 ENOG4105C1G acyl-Coa dehydrogenase EA674_002465 ENOG4105KB2 stringent starvation protein b EA674_002470 ENOG4107MKT Stringent starvation protein a EA674_002475 ENOG4108UJD 30S ribosomal protein S9 EA674_002485 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) EA674_002490 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) EA674_002495 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) EA674_002515 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) EA674_002525 ENOG4107RZC phospholipase d EA674_002535 ENOG4105UYK outer membrane protein a EA674_002540 ENOG4108KHX Diguanylate cyclase EA674_002575 ENOG4107QN2 dihydrolipoyl dehydrogenase EA674_002585 ENOG4107QPB Beta-lactamase domain protein EA674_002590 ENOG4107U2T alpha beta EA674_002600 ENOG4105NAU thioesterase Superfamily protein EA674_002630 ENOG4105K9H YciI-like protein EA674_002640 ENOG4105DB7 PHP domain protein EA674_002645 ENOG4105FFC UPF0187 protein EA674_002655 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase EA674_002660 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) EA674_002665 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) EA674_002670 ENOG4105VIE preprotein translocase, subunit YajC EA674_002720 ENOG4105BZU Histidine kinase EA674_002725 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) EA674_002730 ENOG4105CM2 brancheD-chain amino acid aminotransferase EA674_002745 ENOG4107BJW polysaccharide deacetylase EA674_002755 ENOG4108PQP glycosyl transferase group 1 EA674_002795 ENOG4105UGU tonB-dependent Receptor EA674_002815 ENOG4108VY7 phosphate-starvation-inducible protein PsiE EA674_002820 ENOG4108K3A Glutathione S-transferase EA674_002825 ENOG4108R4R Iron-regulated virulence regulatory protein EA674_002830 ENOG4105CSU acyl-Coa dehydrogenase EA674_002835 ENOG4105CSU acyl-Coa dehydrogenase EA674_002845 ENOG4105EB3 Histidine kinase EA674_002850 ENOG4105E3W Two component transcriptional regulator (Winged helix family EA674_002855 ENOG4105CNG UPF0061 protein EA674_002875 ENOG4108WBT adenosyltransferase EA674_002890 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) EA674_002925 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase EA674_002945 ENOG4105D3R alkyl hydroperoxide reductase EA674_002960 ENOG4105CSH Transporter EA674_002965 ENOG4108UT2 hemolysin iii EA674_002995 ENOG4105CHU acetyl-coa acetyltransferase EA674_003000 ENOG4108R6W Transcriptional regulator, ARAC family EA674_003010 ENOG4105TW1 Carbohydrate-selective porin OprB EA674_003015 ENOG4105DZG Dehydrogenase EA674_003020 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) EA674_003040 ENOG4105CHU acetyl-coa acetyltransferase EA674_003050 ENOG4108WHA ompa motb domain protein EA674_003060 ENOG4105E0Y RtcB Protein EA674_003065 ENOG4108IQI permease EA674_003075 ENOG4105C2W permease EA674_003095 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) EA674_003105 ENOG4108VX5 3-methyladenine DNA glycosylase EA674_003110 ENOG4105CHB tonB-dependent Receptor EA674_003115 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EA674_003130 ENOG4105T95 Thiol disulfide interChange protein EA674_003135 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) EA674_003145 ENOG4105K78 MarR family Transcriptional regulator EA674_003150 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA EA674_003155 ENOG4105KWI UPF0339 protein EA674_003180 ENOG4108UNF response regulator EA674_003185 ENOG4105M3Z response regulator EA674_003190 ENOG4108ZGA chew protein EA674_003195 ENOG4105C8Q Methyl-accepting chemotaxis EA674_003200 ENOG4105CBS Chea signal transduction histidine kinase EA674_003215 ENOG4106HKS Entericidin EcnA/B family EA674_003225 ENOG4105WD1 Membrane EA674_003230 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein EA674_003270 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) EA674_003280 ENOG4105EM2 membrane EA674_003285 ENOG4105C2C drug resistance transporter, Bcr CflA EA674_003305 ENOG4105BZG amino acid carrier protein EA674_003310 ENOG4105D78 K07001 NTE family protein EA674_003315 ENOG4105C7B Threonine dehydratase EA674_003350 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) EA674_003360 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) EA674_003365 ENOG4105DFF Rod shape-determining protein mreb EA674_003370 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) EA674_003375 ENOG4105VQ7 Rod shape-determining protein MreD EA674_003380 ENOG4108Z03 MAF-like protein EA674_003385 ENOG4105C03 ribonuclease EA674_003395 ENOG4105D8T Acyltransferase EA674_003405 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein EA674_003415 ENOG4108X0B nad(p)h dehydrogenase (quinone) EA674_003440 ENOG4105CF7 AraC family transcriptional regulator EA674_003460 ENOG4105C85 amino acid EA674_003465 ENOG4105C7F AcnD-accessory protein PrpF EA674_003470 ENOG4105CTB Polyprenyl synthetase EA674_003475 ENOG4105MSB protein, conserved in bacteria EA674_003490 ENOG4105D78 K07001 NTE family protein EA674_003515 ENOG4105DIJ Phosphoethanolamine transferase EA674_003520 ENOG4105XJC Two component transcriptional regulator (Winged helix family EA674_003525 ENOG4105DHQ Histidine kinase EA674_003545 ENOG4108M0I Transcriptional regulator EA674_003565 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) EA674_003585 ENOG4105K8R UPF0145 protein EA674_003590 ENOG4105K8R UPF0145 protein EA674_003595 ENOG4105ENJ RND efflux system, outer membrane lipoprotein EA674_003600 ENOG4105BZS acriflavin resistance protein EA674_003605 ENOG4105C1P efflux transporter, rnd family, mfp subunit EA674_003610 ENOG410841Q phosphoesterase PA-phosphatase related protein EA674_003640 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) EA674_003655 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) EA674_003660 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) EA674_003665 ENOG4105KVH Transcriptional regulator EA674_003675 ENOG4105CUB amino acid EA674_003690 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) EA674_003695 ENOG41084BA UPF0250 protein EA674_003700 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EA674_003735 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit EA674_003740 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein EA674_003750 ENOG4105E33 succinate dehydrogenase EA674_003765 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 EA674_003770 ENOG4105C7S Dehydrogenase EA674_003775 ENOG4107QN2 dihydrolipoyl dehydrogenase EA674_003785 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha EA674_003795 ENOG4105CKW Inner membrane protein yedI EA674_003800 ENOG4105CGZ zinc metallopeptidase EA674_003805 ENOG4105EEQ Na H antiporter EA674_003850 ENOG4105PNM synthesis protein EA674_003865 ENOG41080TK Universal stress protein EA674_003880 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain EA674_003885 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain EA674_003900 ENOG4105HBR Rna-binding protein EA674_003910 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) EA674_003915 ENOG4105EEI dihydropteroate synthase EA674_003965 ENOG4105CSH Transporter EA674_003970 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) EA674_003975 ENOG4105C6V Glycerol-3-phosphate dehydrogenase EA674_003990 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) EA674_004010 ENOG41080IJ Diacylglycerol kinase EA674_004020 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase EA674_004025 ENOG4105BZS acriflavin resistance protein EA674_004040 ENOG4105E4C Lytic transglycosylase catalytic EA674_004065 ENOG4108RRZ Transcription elongation factor GreB EA674_004080 ENOG4105CEY Amp-dependent synthetase and ligase EA674_004125 ENOG4105BZW Glycerate kinase EA674_004130 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit EA674_004135 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) EA674_004150 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) EA674_004160 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) EA674_004165 ENOG4105C85 amino acid EA674_004175 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) EA674_004185 ENOG4105N14 lysine exporter protein LysE YggA EA674_004190 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EA674_004195 ENOG4105BZJ Electron transfer flavoprotein EA674_004200 ENOG4105C10 Electron transfer flavoprotein EA674_004205 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EA674_004240 ENOG4107KET secretion protein, HlyD family EA674_004270 ENOG4105D60 lipoprotein releasing system transmembrane protein EA674_004275 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) EA674_004280 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 EA674_004290 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) EA674_004295 ENOG4107R6F Alpha Beta Hydrolase Fold protein EA674_004300 ENOG4108V3E phosphoribosylglycinamide formyltransferase EA674_004310 ENOG4105C02 permease EA674_004360 ENOG4105KCK Peptidoglycan-associated lipoprotein EA674_004365 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) EA674_004375 ENOG4105M8F Biopolymer transport protein exbD tolR EA674_004380 ENOG4105E02 MotA TolQ exbB proton channel EA674_004385 ENOG4107YD3 Thioesterase EA674_004390 ENOG4105CH2 amidohydrolase EA674_004410 ENOG4108ETH Formylglycinamide ribotide synthetase EA674_004415 ENOG4105C2C drug resistance transporter, Bcr CflA EA674_004420 ENOG4105EGD dinuclear metal center protein, YbgI family EA674_004425 ENOG4108UKI Enoyl-CoA hydratase EA674_004440 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen EA674_004455 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) EA674_004460 ENOG4107VRB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) EA674_004475 ENOG4107R11 Transcriptional regulator EA674_004480 ENOG4108IJ6 ABC transporter EA674_004490 ENOG4108I5D sulfate abc transporter EA674_004500 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein EA674_004505 ENOG4105YAZ 4-amino-4-deoxychorismate lyase EA674_004510 ENOG4105HHA aminodeoxychorismate lyase EA674_004525 ENOG4108IYU L-aspartate oxidase EA674_004530 ENOG4105C0H protease EA674_004545 ENOG4105C3F Signal peptidase i EA674_004560 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) EA674_004570 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) EA674_004575 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) EA674_004580 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase EA674_004585 ENOG4105EMU Dehydrogenase EA674_004625 ENOG4105BZU Histidine kinase EA674_004635 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) EA674_004645 ENOG4105DTR rard protein EA674_004680 ENOG4107QS8 (LipO)protein EA674_005020 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) EA674_005025 ENOG4105EA8 2-Nitropropane dioxygenase EA674_005055 ENOG4107R8N Glycosyl transferase, family 2 EA674_005070 ENOG4105CVP deoxyribo-dipyrimidine photolyase EA674_005075 ENOG4108YZY peptidylprolyl cis-trans isomerase EA674_005080 ENOG4105CEP NADH dehydrogenase EA674_005095 ENOG4105E9K Isocitrate dehydrogenase EA674_005100 ENOG4108R99 pseudouridine synthase EA674_005125 ENOG4105CBP Major Facilitator EA674_005130 ENOG4105EGI Transcriptional regulator EA674_005135 ENOG4108ETY sodium dicarboxylate symporter EA674_005140 ENOG4105JAB phenazine biosynthesis protein, phzf family EA674_005170 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) EA674_005185 ENOG4105D3G Pseudouridine synthase EA674_005190 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) EA674_005205 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) EA674_005230 ENOG4108JPW Aminotransferase EA674_005235 ENOG4105DY8 decarboxylase EA674_005245 ENOG4105F7P transcriptional regulator AsnC family EA674_005250 ENOG4107RA9 decarboxylase EA674_005255 ENOG4105C85 amino acid EA674_005260 ENOG4105CVA phosphate EA674_005265 ENOG4105C8U phosphate abc transporter EA674_005275 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) EA674_005280 ENOG4105ERU peptidase EA674_005295 ENOG4107QTF adenylosuccinate lyase EA674_005315 ENOG4108Z0R Transferase EA674_005320 ENOG4105DZ1 carboxypeptidase EA674_005340 ENOG4108K5P (LipO)protein EA674_005345 ENOG4105EJC lysr family transcriptional regulator EA674_005350 ENOG4105DAN ATP-dependent protease EA674_005365 ENOG4105DHU Bile acid EA674_005385 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein EA674_005395 ENOG4105D22 carbon starvation protein EA674_005400 ENOG4105VCD cytoplasmic protein EA674_005435 ENOG4108K8K Transcriptional regulator EA674_005450 ENOG4105C26 Dehydrogenase EA674_005455 ENOG4105C85 amino acid EA674_005460 ENOG4105ETT transcriptional Regulator, LysR family EA674_005465 ENOG4105C94 Transporter EA674_005470 ENOG4105C94 Transporter EA674_005480 ENOG4105C26 Dehydrogenase EA674_005485 ENOG4107QZF nitrite reductase NADPH large subunit EA674_005490 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) EA674_005520 ENOG41060M8 Pfam:PhdYeFM EA674_005525 ENOG4107QNK )-transporter EA674_005530 ENOG4107WEA mandelate racemase muconate lactonizing EA674_005540 ENOG4105J7D transcriptional regulator EA674_005560 ENOG4105C2I pirin domain protein EA674_005570 ENOG4105WWK YheO domain protein EA674_005585 ENOG4105CEY Amp-dependent synthetase and ligase EA674_005600 ENOG4108IPW abc transporter atp-binding protein EA674_005625 ENOG4105C0W non-ribosomal peptide synthetase EA674_005630 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase EA674_005635 ENOG4105WQI isochorismatase EA674_005650 ENOG4105BZ1 (ABC) transporter EA674_005670 ENOG4105E4F Isochorismate synthase EA674_005685 ENOG4105NX3 Membrane EA674_005705 ENOG4105EUJ GTP cyclohydrolase i EA674_005715 ENOG4105C7W Xanthine dehydrogenase EA674_005745 ENOG4105CD8 aminopeptidase N EA674_005750 ENOG4105DDQ anthranilate synthase EA674_006070 ENOG4105DFP Integrase EA674_006080 ENOG4105DUX Transporter EA674_006085 ENOG4105C5F glutamine synthetase EA674_006095 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) EA674_006130 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) EA674_006135 ENOG4107QNR UPF0135 protein EA674_006140 ENOG4105C0H protease EA674_006150 ENOG4105C6K Malic enzyme EA674_006155 ENOG4105BZU Histidine kinase EA674_006160 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) EA674_006165 ENOG4105SYT Methylenetetrahydrofolate reductase EA674_006170 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) EA674_006185 ENOG4107QPN acyl-Coa dehydrogenase EA674_006190 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) EA674_006195 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) EA674_006205 ENOG4107RNU major facilitator superfamily MFS_1 EA674_006215 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) EA674_006220 ENOG4105CE9 30S ribosomal protein S2 EA674_006260 ENOG4105CVE Lytic murein transglycosylase EA674_006265 ENOG4105CNI cell division protein FtsW EA674_006280 ENOG4105E3A (ABC) transporter EA674_006285 ENOG4105DA5 (ABC) transporter EA674_006320 ENOG4105ENJ RND efflux system, outer membrane lipoprotein EA674_006330 ENOG4105ENT Efflux transporter rnd family, mfp subunit EA674_006355 ENOG4105DSP amino acid AbC transporter EA674_006360 ENOG4106YG3 ABC transporter EA674_006365 ENOG4108JEH abc transporter atp-binding protein EA674_006375 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding EA674_006380 ENOG4105CFP Peptidase U32 EA674_006385 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EA674_006390 ENOG4105JAB phenazine biosynthesis protein, phzf family EA674_006395 ENOG4105DP0 ferredoxin-NADP reductase EA674_006400 ENOG4108R96 Methyltransferase, YaeB family EA674_006410 ENOG4107QHF type ii secretion system protein e EA674_006420 ENOG4105XJC Two component transcriptional regulator (Winged helix family EA674_006425 ENOG4105DHQ Histidine kinase EA674_006435 ENOG4105M6F mutator MutT protein EA674_006445 ENOG4105BZ4 penicillin-binding protein EA674_006450 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) EA674_006455 ENOG4105VUT cytoplasmic protein EA674_006460 ENOG4107QYG anthranilate phosphoribosyltransferase EA674_006470 ENOG4105CK2 sodium dicarboxylate symporter EA674_006475 ENOG4105C1G acyl-Coa dehydrogenase EA674_006480 ENOG4105NIV Esterase EA674_006485 ENOG4105CQC Prephenate dehydratase EA674_006490 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase EA674_006500 ENOG4105CIN aminoacyl-histidine dipeptidase EA674_006505 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) EA674_006535 ENOG4105M08 Membrane EA674_006540 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EA674_006550 ENOG4105VEQ Cold shock protein EA674_006555 ENOG4105C1J atp-dependent rna helicase EA674_006565 ENOG41069NU Nitroreductase EA674_006600 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase EA674_006615 ENOG4105C5I Dehydrogenase EA674_006620 ENOG4105ERG peptidase m48, ste24p EA674_006625 ENOG4105KTH gatB Yqey EA674_006630 ENOG4105VCC 30S ribosomal protein S21 EA674_006655 ENOG4105D9P serine threonine protein kinase EA674_006680 ENOG4105EVZ LysR family transcriptional regulator EA674_006685 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) EA674_006690 ENOG4105C26 Dehydrogenase EA674_006725 ENOG4105H4F exported protein EA674_006755 ENOG4105D6U Sodium Glutamate Symporter EA674_006765 ENOG4105JXH GntR family transcriptional regulator EA674_006815 ENOG4105CSH Transporter EA674_006840 ENOG4105CEB Aspartate aminotransferase EA674_006855 ENOG4105F1S paraquat-inducible protein a EA674_006860 ENOG4105DY2 Paraquat-inducible protein b EA674_006900 ENOG4105CK2 sodium dicarboxylate symporter EA674_006910 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) EA674_006915 ENOG4108UMI ABC transporter, permease EA674_006920 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) EA674_006930 ENOG4105C12 Phosphoribosylglycinamide synthetase EA674_006935 ENOG4105DC1 bifunctional purine biosynthesis protein purh EA674_006940 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) EA674_006990 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) EA674_006995 ENOG4105CDU Replicative dna helicase EA674_007020 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) EA674_007025 ENOG4105CCU oxidase (Subunit III) EA674_007030 ENOG4105BZ9 Cytochrome C oxidase, subunit I EA674_007035 ENOG4105E2S oxidase) subunit II EA674_007060 ENOG4107BJW polysaccharide deacetylase EA674_007065 ENOG4105CND Glycosyl transferase, family 2 EA674_007070 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD EA674_007080 ENOG4105DEN Luciferase family EA674_007100 ENOG4105CC0 LysR family Transcriptional regulator EA674_007115 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) EA674_007120 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component EA674_007125 ENOG4105GVF (ABC) transporter EA674_007140 ENOG4105C1G acyl-Coa dehydrogenase EA674_007150 ENOG4108MEJ flavin reductase domain protein EA674_007155 ENOG4105D06 uba thif-type nad fad binding protein EA674_007175 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) EA674_007180 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) EA674_007190 ENOG4105C08 Histidine kinase EA674_007195 ENOG4105EEX Two component transcriptional regulator (Winged helix family EA674_007200 ENOG4105CFQ glutamine synthetase EA674_007215 ENOG4107S74 Lysophospholipid transporter LplT EA674_007220 ENOG4105CFU surface antigen EA674_007240 ENOG4107QIJ Aconitate hydratase 2 EA674_007250 ENOG4105EYW Ion transport protein EA674_007255 ENOG4105F27 Major Facilitator EA674_007270 ENOG4105DZ2 Transcriptional regulator EA674_007305 ENOG4105K8N protein family UPF0079, ATPase EA674_007310 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) EA674_007320 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) EA674_007325 ENOG4108TZV Membrane EA674_007330 ENOG4108RCM Nitroreductase EA674_007340 ENOG4105F10 Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity) EA674_007355 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) EA674_007360 ENOG4107FQ9 ethanolamine ammonia-lyase EA674_007365 ENOG4105CPD ethanolamine ammonia-lyase EA674_007370 ENOG4107R55 ethanolamine transporter EA674_007380 ENOG4107RR1 TRANSCRIPTIONal EA674_007390 ENOG4105C0A alcohol dehydrogenase EA674_007395 ENOG4107QUV Domain protein EA674_007405 ENOG4105F4I Transcriptional regulator EA674_007425 ENOG4105CD8 aminopeptidase N EA674_007435 ENOG4105EMU Dehydrogenase EA674_007445 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) EA674_007450 ENOG4105EW9 transcriptional regulator AsnC family EA674_007465 ENOG4105R8C Transcriptional regulator EA674_007475 ENOG4105CUY Mechanosensitive ion channel EA674_007505 ENOG4105CNM Receptor EA674_007525 ENOG4105C5H ABC transporter EA674_007530 ENOG41081QV Universal stress protein EA674_007545 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic EA674_007555 ENOG4105DKK Benzoate EA674_007560 ENOG4105EW9 transcriptional regulator AsnC family EA674_007565 ENOG4108NIW Leucine export protein LeuE EA674_007570 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) EA674_007575 ENOG4105C5Q Transcriptional regulator EA674_007585 ENOG4105CHU acetyl-coa acetyltransferase EA674_007590 ENOG4105CHR reductase EA674_007615 ENOG4107QMP dna polymerase iii subunits gamma and tau EA674_007620 ENOG4105HSS phospholipase C EA674_007630 ENOG4105C0A alcohol dehydrogenase EA674_007660 ENOG4105CBC glutamate synthase EA674_008030 ENOG4105D8G Major Facilitator superfamily EA674_008040 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase EA674_008045 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein EA674_008070 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EA674_008080 ENOG4107QZF nitrite reductase NADPH large subunit EA674_008085 ENOG4108IFG nitrite reductase, (NAD(P)H) EA674_008105 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) EA674_008120 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) EA674_008125 ENOG4105CVM Molybdenum cofactor synthesis domain protein EA674_008135 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EA674_008140 ENOG4105T38 integral membrane protein EA674_008160 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) EA674_008165 ENOG4105CMR udp-glucose 4-epimerase EA674_008225 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EA674_008230 ENOG4105CUX Signal transduction histidine kinase EA674_008255 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) EA674_008260 ENOG4105KNE Phosphatidate cytidylyltransferase EA674_008270 ENOG4105DZP Membrane-associated zinc metalloprotease EA674_008295 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) EA674_008310 ENOG4105Y3E Modulates RecA activity (By similarity) EA674_008320 ENOG4105VEJ Heat shock protein EA674_008325 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 EA674_008350 ENOG4105F7P transcriptional regulator AsnC family EA674_008360 ENOG4105C85 amino acid EA674_008375 ENOG4105CHH sulfate transporter EA674_008410 ENOG4105BZ1 (ABC) transporter EA674_008460 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) EA674_008525 ENOG4105D8V Glucose sorbosone dehydrogenase EA674_008535 ENOG4105BZU Histidine kinase EA674_008555 ENOG4105DM4 PTS System EA674_008560 ENOG4105DE4 1-phosphofructokinase EA674_008565 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) EA674_008590 ENOG4105CWM branched-chain amino acid transport system II carrier protein EA674_008595 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) EA674_008600 ENOG4105CC0 LysR family Transcriptional regulator EA674_008610 ENOG4105M2J Glutaredoxin EA674_008615 ENOG4105C8Y Acetylornithine aminotransferase EA674_008620 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) EA674_008645 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) EA674_008655 ENOG41068P6 UPF0319 protein EA674_008675 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii EA674_008680 ENOG4105C4M (Ubiquinol oxidase) subunit I EA674_008695 ENOG4105PV3 Inner membrane protein yqiJ EA674_008710 ENOG4105E0K tonB-dependent siderophore receptor EA674_008720 ENOG4105HDD phospholipase EA674_008725 ENOG4105CZN Potassium uptake protein EA674_008735 ENOG4105C7B Threonine dehydratase EA674_008765 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) EA674_008770 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EA674_008780 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) EA674_008795 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EA674_008840 ENOG4107VMU Membrane EA674_008845 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) EA674_008855 ENOG4107QP7 CoA-transferase subunit A EA674_008860 ENOG4107QNJ CoA-transferase subunit B EA674_008865 ENOG4105CHU acetyl-coa acetyltransferase EA674_008870 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase EA674_008875 ENOG4105F2Z 3-oxoadipate enol-lactonase EA674_008880 ENOG4105D2S major facilitator superfamily EA674_008885 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase EA674_008890 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta EA674_008895 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha EA674_008900 ENOG4105FF2 Type I DHQase EA674_008905 ENOG4106JPM 3-dehydroshikimate dehydratase EA674_008910 ENOG4105TW1 Carbohydrate-selective porin OprB EA674_008915 ENOG4105DZG Dehydrogenase EA674_008925 ENOG4105MD1 YeeE YedE family protein EA674_008940 ENOG4107HP6 Transcriptional regulator EA674_008945 ENOG4108PTX LysR family Transcriptional regulator EA674_008950 ENOG4105C1G acyl-Coa dehydrogenase EA674_008975 ENOG4105DNH Major Facilitator EA674_008985 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) EA674_009005 ENOG4105FUY alpha subunit EA674_009015 ENOG4105CHR reductase EA674_009035 ENOG4105F11 amine oxidase EA674_009045 ENOG4105C26 Dehydrogenase EA674_009055 ENOG4105F2Z 3-oxoadipate enol-lactonase EA674_009060 ENOG4105CHU acetyl-coa acetyltransferase EA674_009065 ENOG4107QNJ CoA-transferase subunit B EA674_009070 ENOG4107QP7 CoA-transferase subunit A EA674_009080 ENOG4105NN7 muconolactone delta-isomerase EA674_009085 ENOG4105DTQ mandelate racemase muconate lactonizing EA674_009090 ENOG4108KB2 LysR family Transcriptional regulator EA674_009100 ENOG4107EJG GntR family transcriptional regulator EA674_009120 ENOG4105CZJ Aldehyde dehydrogenase EA674_009140 ENOG4105C1G acyl-Coa dehydrogenase EA674_009145 ENOG4105CHR reductase EA674_009150 ENOG4108JU7 Transcriptional regulator EA674_009160 ENOG41062QD Membrane EA674_009175 ENOG4107RGH Aldehyde dehydrogenase EA674_009190 ENOG4105CH6 catalase EA674_009215 ENOG4105K56 Transcriptional regulator EA674_009220 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EA674_009230 ENOG4105NAE bifunctional deaminase-reductase domain protein EA674_009260 ENOG4107Z3H Transcriptional regulator, TetR family EA674_009270 ENOG4105CHJ isochorismatase hydrolase EA674_009280 ENOG4105EJC lysr family transcriptional regulator EA674_009285 ENOG4105D8V Glucose sorbosone dehydrogenase EA674_009290 ENOG4105CKD glutathione-regulated potassium-efflux system protein EA674_009300 ENOG4105CH2 amidohydrolase EA674_009320 ENOG4105D5K Hemolysin activator protein EA674_009325 ENOG4105CKT filamentous hemagglutinin EA674_009355 ENOG4105FDP GntR family transcriptional regulator EA674_009370 ENOG4106KR7 LysR family Transcriptional regulator EA674_009395 ENOG4108JQ1 Dehydrogenase EA674_009400 ENOG4105JSC dimethylmenaquinone methyltransferase EA674_009420 ENOG4105CW7 secretion protein, HlyD family EA674_009435 ENOG4105CZJ Aldehyde dehydrogenase EA674_009440 ENOG4105C01 Dihydroxy-acid dehydratase EA674_009450 ENOG4105DDW LysR family Transcriptional regulator EA674_009455 ENOG4105EXW epimerase dehydratase EA674_009465 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase EA674_009470 ENOG4105CF7 AraC family transcriptional regulator EA674_009485 ENOG4105DQ4 alcohol dehydrogenase EA674_009495 ENOG4105EHG Permease protein EA674_009500 ENOG4105E0A ABC, transporter EA674_009520 ENOG4105C5T Phosphoribosyl pyrophosphate synthase EA674_009600 ENOG4108UAJ Transcriptional regulator EA674_009640 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) EA674_009695 ENOG4108BAS reductase EA674_009710 ENOG4108R6W Transcriptional regulator, ARAC family EA674_009715 ENOG4108821 RND type efflux pump EA674_009725 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EA674_009730 ENOG4105C1P efflux transporter, rnd family, mfp subunit EA674_009735 ENOG4105BZS acriflavin resistance protein EA674_009740 ENOG4105ENJ RND efflux system, outer membrane lipoprotein EA674_009750 ENOG4105CT3 Monooxygenase EA674_009770 ENOG4105CJP fad dependent oxidoreductase EA674_009790 ENOG4105X0I Fimbrial EA674_009845 ENOG4107RZC phospholipase d EA674_009865 ENOG4108IGT Dipeptidase EA674_009900 ENOG4107T31 5'-nucleotidase EA674_009910 ENOG4105WQI isochorismatase EA674_009915 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase EA674_009920 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) EA674_009925 ENOG4105E0C molybdate abc transporter EA674_009930 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein EA674_009935 ENOG4105F4R Transcriptional regulator mode EA674_009940 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit EA674_009945 ENOG4108YS2 small subunit EA674_009950 ENOG4105F57 Anthranilate dioxygenase reductase EA674_009975 ENOG4105CHR reductase EA674_009985 ENOG4105D2S major facilitator superfamily EA674_009990 ENOG4105CF7 AraC family transcriptional regulator EA674_010000 ENOG4105DTD Dehydrogenase EA674_010005 ENOG4105CY2 Citrate transporter EA674_010015 ENOG4108M0I Transcriptional regulator EA674_010025 ENOG4107QNJ CoA-transferase subunit B EA674_010030 ENOG4105CRW Short chain fatty acid transporter EA674_010035 ENOG4105CHU acetyl-coa acetyltransferase EA674_010045 ENOG4107YNJ LysR family Transcriptional regulator EA674_010060 ENOG4108IJ0 Aspartate ammonia-lyase EA674_010070 ENOG4105CSH Transporter EA674_010090 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component EA674_010095 ENOG4106FTQ Taurine ABC transporter, periplasmic EA674_010110 ENOG4105FDP GntR family transcriptional regulator EA674_010120 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) EA674_010125 ENOG4105KVH Transcriptional regulator EA674_010130 ENOG4105UEI Transcriptional Regulator AraC Family EA674_010145 ENOG4108VCT Sulfite exporter TauE/SafE EA674_010155 ENOG4107QPB Beta-lactamase domain protein EA674_010165 ENOG4105FFC UPF0187 protein EA674_010175 ENOG4105CHR reductase EA674_010190 ENOG4105CPP Dehydrogenase, E1 component EA674_010195 ENOG4107R0V Pyruvate dehydrogenase EA674_010200 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) EA674_010215 ENOG4105BZU Histidine kinase EA674_010225 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) EA674_010230 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) EA674_010275 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) EA674_010290 ENOG4105C28 cystathionine EA674_010300 ENOG4105F2W methyltransferase EA674_010330 ENOG4105K59 histidine triad (HIT) protein EA674_010355 ENOG4107QWP ABC-2 type transporter EA674_010360 ENOG4107QWP ABC-2 type transporter EA674_010365 ENOG4105CJ1 ABC, transporter EA674_010380 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) EA674_010385 ENOG4105CNM Receptor EA674_010405 ENOG4107TSN permease EA674_010410 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) EA674_010430 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) EA674_010435 ENOG4108YZT Adenosylcobinamide kinase EA674_010490 ENOG4105DJU Siderophore biosynthesis protein EA674_010495 ENOG4105DUU IucA IucC family protein EA674_010515 ENOG4108Z66 YbaK ebsC protein EA674_010530 ENOG4105C1G acyl-Coa dehydrogenase EA674_010535 ENOG4105C1G acyl-Coa dehydrogenase EA674_010540 ENOG4105EEF Alkane 1-monooxygenase EA674_010545 ENOG4105E7U AraC family transcriptional regulator EA674_010550 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) EA674_010555 ENOG4105K70 DNA-binding protein EA674_010570 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family EA674_010580 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins EA674_010585 ENOG4108Z4V iron-sulfur cluster assembly EA674_010600 ENOG4108ZIT Ferredoxin, 2FE-2S EA674_010605 ENOG4105F8J Adenylate Guanylate cyclase EA674_010615 ENOG4108JA2 transcriptioN-repair coupling factor EA674_010635 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) EA674_010640 ENOG4105K4T epimerase EA674_010655 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase EA674_010675 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component EA674_010685 ENOG4105DGW oligopeptidase A EA674_010725 ENOG4105SG9 biopolymer transport protein, ExbD EA674_010735 ENOG4107QP3 malate synthase g EA674_010740 ENOG4105D6Z AFG1 family ATPase EA674_010750 ENOG4107RN6 Monooxygenase EA674_010770 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) EA674_010775 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) EA674_010790 ENOG4108Z6B deaminase EA674_010810 ENOG4108RTD type II secretion system protein K EA674_010835 ENOG4105F8V Hydrolase, tatD family EA674_010845 ENOG4107QRG dna polymerase iii EA674_010855 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) EA674_010860 ENOG4105BZ1 (ABC) transporter EA674_010875 ENOG4105FA0 parb-like partition protein EA674_010880 ENOG4107QJE Chromosome Partitioning Protein EA674_010890 ENOG4108S0S Nucleotidyl transferase EA674_010895 ENOG4105EHM Aminoglycoside phosphotransferase EA674_010900 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) EA674_010905 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) EA674_010910 ENOG4105D2N Aldolase EA674_010930 ENOG4108UHJ MAF-like protein EA674_010935 ENOG4105EZE Cupin 4 family protein EA674_010945 ENOG41080HT Transcriptional regulator, arsr family EA674_010955 ENOG4105XPP Protein of unknown function (DUF1275) EA674_010960 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme EA674_010965 ENOG4105BZ1 (ABC) transporter EA674_010975 ENOG4108ZX5 transcriptional regulator EA674_010985 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) EA674_010990 ENOG4105CK7 Sodium proline symporter EA674_010995 ENOG4105EW9 transcriptional regulator AsnC family EA674_011000 ENOG4105C26 Dehydrogenase EA674_011005 ENOG4105YGK Pfam:UPF0157 EA674_011020 ENOG4108T58 Mg2 transport protein CorA EA674_011030 ENOG4108YYC ycei family EA674_011040 ENOG4105CV1 Transketolase (EC 2.2.1.1) EA674_011070 ENOG4108HWY Beta-lactamase EA674_011090 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) EA674_011095 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) EA674_011115 ENOG4105X0I Fimbrial EA674_011120 ENOG4105GQR Chaperone EA674_011150 ENOG4108IPJ Membrane EA674_011160 ENOG4105ETS cytosine purines uracil thiamine allantoin EA674_011170 ENOG4105CC0 LysR family Transcriptional regulator EA674_011190 ENOG41067SE Tetr family transcriptional regulator EA674_011205 ENOG4105EW9 transcriptional regulator AsnC family EA674_011215 ENOG4105CDA abc transporter atp-binding protein EA674_011220 ENOG4105DRP amino acid AbC transporter EA674_011225 ENOG4105EAD ABC transporter EA674_011240 ENOG4107T8P acyl-Coa dehydrogenase EA674_011255 ENOG4105D01 (LipO)protein EA674_011260 ENOG4105D01 (LipO)protein EA674_011265 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) EA674_011270 ENOG4108UMI ABC transporter, permease EA674_011275 ENOG4105C3G gtp-binding protein EA674_011300 ENOG4108UMN azlc family EA674_011305 ENOG4105ZED uncharacterized protein ygaH EA674_011335 ENOG4105E7U AraC family transcriptional regulator EA674_011340 ENOG4108V06 Glutathione peroxidase EA674_011350 ENOG4105CHM Aminotransferase EA674_011365 ENOG4105C0B DNA polymerase III (alpha subunit) EA674_011390 ENOG4108JU3 Alkyl hydroperoxide reductase EA674_011405 ENOG4108KB2 LysR family Transcriptional regulator EA674_011410 ENOG4105D6J arsenicaL-resistance protein EA674_011415 ENOG41082YX Transcriptional regulator, arsr family EA674_011430 ENOG4105CPN adenine deaminase EA674_011440 ENOG4105CBN LysR family transcriptional regulator EA674_011450 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease EA674_011460 ENOG4105E2B Taurine dioxygenase EA674_011465 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component EA674_011470 ENOG4108IY8 ABC, transporter EA674_011475 ENOG4106FTQ Taurine ABC transporter, periplasmic EA674_011485 ENOG4105C54 Major Facilitator superfamily EA674_011510 ENOG4105C4M (Ubiquinol oxidase) subunit I EA674_011515 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii EA674_011525 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EA674_011530 ENOG4108K70 Transcriptional regulator EA674_011545 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase EA674_011550 ENOG4105PSI phosphoribosyl-dephospho-CoA transferase EA674_011565 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) EA674_011570 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase EA674_011580 ENOG4105DXI Major Facilitator superfamily EA674_011600 ENOG41067MG lrgb family EA674_011605 ENOG4105VAW lrga family EA674_011610 ENOG4105CMU LysR family (Transcriptional regulator EA674_011615 ENOG4108SHQ Glutathione S-transferase EA674_011620 ENOG4105CYM Glutathione S-transferase EA674_011625 ENOG4105CBN LysR family transcriptional regulator EA674_011630 ENOG4105CHR reductase EA674_011640 ENOG4105D7W serine acetyltransferase EA674_011645 ENOG4105ESN nucleotide-binding protein EA674_011650 ENOG4105C9B Cysteine desulfurase EA674_011665 ENOG4105EXG Transcriptional regulator EA674_011675 ENOG4105CT1 (ABC) transporter EA674_011680 ENOG4107RP9 extracellular solute-binding protein, family 3 EA674_011685 ENOG4105CDA abc transporter atp-binding protein EA674_011690 ENOG4108HW4 amino acid AbC transporter EA674_011695 ENOG4105EAD ABC transporter EA674_011710 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase EA674_011715 ENOG4105BZU Histidine kinase EA674_011725 ENOG4105EW9 transcriptional regulator AsnC family EA674_011735 ENOG4105KT5 UmuD protein EA674_011755 ENOG4105CYX Short-chain dehydrogenase reductase Sdr EA674_011800 ENOG4105HEI LysR family (Transcriptional regulator EA674_011820 ENOG4105CEY Amp-dependent synthetase and ligase EA674_011825 ENOG4105R8C Transcriptional regulator EA674_011830 ENOG4105C1G acyl-Coa dehydrogenase EA674_011835 ENOG4107QX3 carboxylase EA674_011840 ENOG4105E39 Enoyl-CoA hydratase EA674_011855 ENOG4105CC0 LysR family Transcriptional regulator EA674_011870 ENOG4105CSU acyl-Coa dehydrogenase EA674_011880 ENOG4105EQ0 Major Facilitator superfamily EA674_011890 ENOG4107QNJ CoA-transferase subunit B EA674_011895 ENOG4107QP7 CoA-transferase subunit A EA674_011900 ENOG4107RGD Major Facilitator superfamily EA674_011905 ENOG4105C1G acyl-Coa dehydrogenase EA674_011910 ENOG4105E39 Enoyl-CoA hydratase EA674_011915 ENOG4105CHR reductase EA674_011920 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase EA674_011925 ENOG4105CHU acetyl-coa acetyltransferase EA674_011935 ENOG4105EQ0 Major Facilitator superfamily EA674_011940 ENOG4105EA8 2-Nitropropane dioxygenase EA674_011945 ENOG4108UKI Enoyl-CoA hydratase EA674_011960 ENOG4105C1G acyl-Coa dehydrogenase EA674_011965 ENOG4107RGD Major Facilitator superfamily EA674_011970 ENOG4108KAZ Involved in phosphonate degradation (By similarity) EA674_011975 ENOG4107STF Involved in phosphonate degradation (By similarity) EA674_011985 ENOG4107RCV ABC transporter, permease EA674_011990 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) EA674_011995 ENOG4105C4Y ABC transporter EA674_012005 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase EA674_012010 ENOG4107HP6 Transcriptional regulator EA674_012020 ENOG4105HEI LysR family (Transcriptional regulator EA674_012025 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase EA674_012030 ENOG4105C26 Dehydrogenase EA674_012040 ENOG4105ETS cytosine purines uracil thiamine allantoin EA674_012050 ENOG4105C26 Dehydrogenase EA674_012055 ENOG4108M8W Monooxygenase EA674_012060 ENOG4105MXW flavin reductase domain protein, FMN-binding EA674_012065 ENOG4108MXF Alpha Beta Hydrolase EA674_012085 ENOG4105CPW cytochrome b561 EA674_012090 ENOG4107VGR Catalase EA674_012130 ENOG4107YAU phenylacetic acid degradation protein EA674_012140 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein EA674_012145 ENOG4105DZS Phenylacetate-CoA ligase EA674_012150 ENOG4105CHU acetyl-coa acetyltransferase EA674_012155 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase EA674_012160 ENOG4108UKI Enoyl-CoA hydratase EA674_012165 ENOG4105E39 Enoyl-CoA hydratase EA674_012170 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) EA674_012175 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit EA674_012180 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit EA674_012185 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit EA674_012190 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit EA674_012195 ENOG4105DXM phenylacetic acid degradation protein EA674_012200 ENOG4105EJQ L-serine dehydratase EA674_012205 ENOG4107QTZ amino acid EA674_012210 ENOG4105CZJ Aldehyde dehydrogenase EA674_012235 ENOG4105MWK D-amino acid dehydrogenase, small subunit EA674_012255 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EA674_012270 ENOG4108Z4X TRANSCRIPTIONal EA674_012285 ENOG4105WPN DNA integration recombination invertion protein EA674_012300 ENOG4105DJ2 Major Facilitator Superfamily EA674_012305 ENOG4107Y2X deaminase EA674_012315 ENOG4105EMY transcriptional regulator EA674_012345 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EA674_012355 ENOG4105UYK outer membrane protein a EA674_012430 ENOG4108HW3 (ABC) transporter EA674_012440 ENOG4105MRR Transcriptional regulator (By similarity) EA674_012460 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF EA674_012465 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase EA674_012480 ENOG4105E2A Dehydrogenase EA674_012490 ENOG4105R8C Transcriptional regulator EA674_012515 ENOG4107R4J Chloride channel EA674_012520 ENOG4108JIK carboxylase EA674_012540 ENOG4105C5A transporter EA674_012545 ENOG4108WAV Transcriptional regulator EA674_012560 ENOG4105CNA YD repeat protein EA674_012600 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) EA674_012620 ENOG4105D2S major facilitator superfamily EA674_012635 ENOG4105D1S lipid A biosynthesis EA674_012640 ENOG4105BZU Histidine kinase EA674_012645 ENOG4107AQZ Membrane EA674_012665 ENOG4108Z4U Ferredoxin EA674_012705 ENOG4105DFG type I secretion outer membrane protein EA674_012710 ENOG4108IUZ ABC transporter EA674_012715 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA EA674_012725 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase EA674_012730 ENOG4105C2X Arabinose 5-phosphate isomerase EA674_012765 ENOG4107YPT transcriptional regulator EA674_012800 ENOG4105II7 pyrroline-5-carboxylate reductase EA674_012810 ENOG4105VEQ Cold shock protein EA674_012815 ENOG410829K Lysine exporter protein (Lyse ygga) EA674_012845 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) EA674_012900 ENOG4108KB2 LysR family Transcriptional regulator EA674_012905 ENOG4105FUY alpha subunit EA674_012910 ENOG4108UKV benzoate 1,2-dioxygenase EA674_012915 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein EA674_012920 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase EA674_012925 ENOG4105DKK Benzoate EA674_012930 ENOG4105D2S major facilitator superfamily EA674_012945 ENOG4105CQ7 ATP-dependent helicase EA674_012950 ENOG4105D3R alkyl hydroperoxide reductase EA674_012960 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) EA674_012970 ENOG4108JU3 Alkyl hydroperoxide reductase EA674_012980 ENOG4108K3A Glutathione S-transferase EA674_012990 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) EA674_012995 ENOG4108TGY Glutathione S-transferase EA674_013005 ENOG4108ZG0 Ompa motb domain protein EA674_013010 ENOG4105CD3 dihydroorotase EA674_013040 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EA674_013055 ENOG4108UKZ OsmC family EA674_013060 ENOG4107RYR Transcriptional regulator, Crp Fnr family EA674_013065 ENOG4105CPC Aldo Keto reductase EA674_013080 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis EA674_013090 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase EA674_013100 ENOG4105CFH Aspartokinase EA674_013110 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) EA674_013120 ENOG4105CPW cytochrome b561 EA674_013125 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) EA674_013130 ENOG4105C7N Xanthine uracil vitamin C permease EA674_013140 ENOG4105F95 Monooxygenase EA674_013235 ENOG4105D01 (LipO)protein EA674_013240 ENOG4108M3P Membrane EA674_013255 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EA674_013275 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) EA674_013295 ENOG4108JQ5 ABC transporter EA674_013300 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component EA674_013305 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component EA674_013315 ENOG4105E9H Lytic Murein transglycosylase EA674_013315 ENOG4105E9H Lytic Murein transglycosylase EA674_013320 ENOG4107RZZ dna polymerase iii epsilon subunit EA674_013330 ENOG4105E09 nadh pyrophosphatase EA674_013340 ENOG4105W4M Transport-associated protein EA674_013350 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) EA674_013360 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) EA674_013365 ENOG4108ZUB Lysine exporter protein (Lyse ygga) EA674_013385 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family EA674_013390 ENOG4105D0A hydroxylase EA674_013395 ENOG4107RAQ aminopeptidase EA674_013430 ENOG4105DIJ Phosphoethanolamine transferase EA674_013475 ENOG4105DR5 peptidase EA674_013800 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase EA674_013825 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b EA674_013835 ENOG4105D82 Glutamate dehydrogenase EA674_013840 ENOG4108R3D Electron transport complex EA674_013845 ENOG4105CSM endonuclease III EA674_013870 ENOG4105CJN penicillin-binding protein EA674_013875 ENOG4106H78 methyltransferase EA674_013890 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) EA674_013900 ENOG4105CQM Urea amidohydrolase subunit alpha EA674_013930 ENOG4107RET Isocitrate lyase EA674_013940 ENOG4105C37 (CBS) domain EA674_013950 ENOG4105D4T Citrate transporter EA674_013965 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) EA674_013980 ENOG4108MRJ EA674_014000 ENOG4105VCQ rubredoxin EA674_014005 ENOG4107QZF nitrite reductase NADPH large subunit EA674_014015 ENOG4105C5Q Transcriptional regulator EA674_014035 ENOG4107U91 Rhomboid family EA674_014040 ENOG4105CV6 ABC transporter, permease EA674_014045 ENOG4108I0Y (ABC) transporter EA674_014050 ENOG4108UJV acyl-CoA thioesterase i EA674_014070 ENOG4107RNH Outer membrane receptor FepA EA674_014085 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) EA674_014090 ENOG4105E6M Sulphatase-modifying factor protein EA674_014110 ENOG4105CJ3 phosphate transporter EA674_014115 ENOG4105C3R Methionine synthase EA674_014130 ENOG4105CSP Major Facilitator Superfamily EA674_014140 ENOG4108PZW LysR family Transcriptional regulator EA674_014155 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) EA674_014160 ENOG4105EU0 Major facilitator Superfamily EA674_014165 ENOG4108R6W Transcriptional regulator, ARAC family EA674_014170 ENOG4105CSV Glutaminase EA674_014175 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) EA674_014180 ENOG4105CSH Transporter EA674_014190 ENOG4105C7K acetolactate synthase EA674_014205 ENOG4105CHR reductase EA674_014210 ENOG4108MXF Alpha Beta Hydrolase EA674_014220 ENOG4105DJB Major Facilitator Superfamily EA674_014225 ENOG4108DNI pyridine nucleotide-disulfide oxidoreductase EA674_014235 ENOG4105CHR reductase EA674_014255 ENOG41069M3 Transcriptional regulator EA674_014270 ENOG4106YT9 Enoyl-CoA hydratase EA674_014280 ENOG4105CND Glycosyl transferase, family 2 EA674_014285 ENOG4107BJW polysaccharide deacetylase EA674_014295 ENOG4108VWS Yaeq family EA674_014305 ENOG4105CKI cobalamin synthesis protein EA674_014325 ENOG4105C94 Transporter EA674_014330 ENOG4105C94 Transporter EA674_014335 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) EA674_014360 ENOG4107QK5 Homocysteine s-methyltransferase EA674_014365 ENOG4105D5Q Arginine ornithine antiporter EA674_014390 ENOG4108YNN Heme oxygenase EA674_014420 ENOG4108SF5 RNA Polymerase EA674_014430 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EA674_014435 ENOG4105C54 Major Facilitator superfamily EA674_014560 ENOG4105DFP Integrase EA674_014570 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) EA674_014575 ENOG4105C0R drug resistance transporter emrb qaca subfamily EA674_014580 ENOG4105CW7 secretion protein, HlyD family EA674_014585 ENOG4108VUY thioesterase Superfamily protein EA674_014590 ENOG4105D52 delta-aminolevulinic acid dehydratase EA674_014595 ENOG4105MWK D-amino acid dehydrogenase, small subunit EA674_014600 ENOG4105ECP epimerase EA674_014620 ENOG4107RH8 nuclease SbcCD subunit D EA674_014625 ENOG4105EYH Exonuclease EA674_014630 ENOG4105DFA alanine racemase domain protein EA674_014635 ENOG4105CZX twitching motility protein EA674_014640 ENOG4105CZX twitching motility protein EA674_014645 ENOG41090R7 Ferric uptake EA674_014675 ENOG4105E7A Glutamine amidotransferase EA674_014690 ENOG4107QKV phosphomannomutase EA674_014700 ENOG4105C4R Atp-dependent dna helicase EA674_014705 ENOG4108ZG0 Ompa motb domain protein EA674_014710 ENOG4106HNH Acyl-transferase EA674_014725 ENOG4107QMS site-determining protein EA674_014750 ENOG4105CNU cell division protein FtsK EA674_014755 ENOG4105C3M thioredoxin reductase EA674_014760 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) EA674_014770 ENOG4105KEG ribosomal-protein-alanine acetyltransferase EA674_014815 ENOG4108YXA Membrane EA674_014820 ENOG4105EUB pirin domain protein EA674_014830 ENOG4105C4K Nad synthetase EA674_014845 ENOG4105E3J oxidoreductase EA674_014850 ENOG4105C26 Dehydrogenase EA674_014855 ENOG4105DVW rieske (2Fe-2S) EA674_014865 ENOG4105C94 Transporter EA674_014870 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) EA674_014875 ENOG4105EJC lysr family transcriptional regulator EA674_014895 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding EA674_014915 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase EA674_014920 ENOG4105C34 Pseudouridine synthase EA674_014925 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane EA674_014930 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) EA674_014945 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) EA674_014975 ENOG4105C5T Phosphoribosyl pyrophosphate synthase EA674_015005 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) EA674_015015 ENOG4105DWF phosphomethylpyrimidine kinase EA674_015020 ENOG4109066 lysm domain bon superfamily protein EA674_015030 ENOG4105CHR reductase EA674_015035 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase EA674_015045 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein EA674_015050 ENOG4108BPE -transporting atpase EA674_015055 ENOG4107RTD sua5 ycio yrdc ywlc family protein EA674_015060 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) EA674_015065 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) EA674_015070 ENOG4105FE9 pseudouridine synthase EA674_015080 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) EA674_015085 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) EA674_015095 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) EA674_015100 ENOG4108K4C ec 3.1.3.12 EA674_015105 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase EA674_015110 ENOG4106UW1 Major Facilitator superfamily EA674_015130 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) EA674_015140 ENOG4105HF0 Membrane EA674_015155 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY EA674_015165 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) EA674_015225 ENOG4105D1F ATP-binding protein EA674_015235 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) EA674_015265 ENOG4105K6H D-cysteine desulfhydrase EA674_015270 ENOG4105CBX hi0933 family EA674_015295 ENOG4105DP0 ferredoxin-NADP reductase EA674_015300 ENOG4105DUM transcriptional regulator, lysR family EA674_015320 ENOG4105C8S subunit m EA674_015325 ENOG4105D65 subunit l EA674_015335 ENOG4107UFS subunit j EA674_015350 ENOG4108IEH NADH dehydrogenase subunit g EA674_015355 ENOG4107QIZ NADH dehydrogenase EA674_015360 ENOG4105GKE subunit e EA674_015380 ENOG4105BZU Histidine kinase EA674_015390 ENOG4105E0F Histidine kinase EA674_015395 ENOG4107EXC regulatoR EA674_015405 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) EA674_015415 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) EA674_015425 ENOG4105EB3 Histidine kinase EA674_015495 ENOG4105DZG Dehydrogenase EA674_015515 ENOG4105JAB phenazine biosynthesis protein, phzf family EA674_015545 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) EA674_015550 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) EA674_015560 ENOG4105ETT transcriptional Regulator, LysR family EA674_015580 ENOG4105CH2 amidohydrolase EA674_015590 ENOG4106P55 Transcriptional regulator EA674_015610 ENOG4106P55 Transcriptional regulator EA674_015615 ENOG4107EFR Flavocytochrome c EA674_015625 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F EA674_015630 ENOG4107RGD Major Facilitator superfamily EA674_015635 ENOG4105C1G acyl-Coa dehydrogenase EA674_015640 ENOG4105ETT transcriptional Regulator, LysR family EA674_015675 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) EA674_015680 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) EA674_015685 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) EA674_015700 ENOG4105VR0 copper resistance EA674_015705 ENOG4105E3B Multicopper oxidase EA674_015715 ENOG4108HCJ Hydrolase EA674_015720 ENOG4105DJV ribulose-phosphate 3-epimerase EA674_015745 ENOG41072GX Peptidase M22 Glycoprotease EA674_015750 ENOG4108Z0R Transferase EA674_015795 ENOG4105CRQ synthase (Component I) EA674_015805 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) EA674_015810 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) EA674_015815 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) EA674_015885 ENOG4105K56 Transcriptional regulator EA674_015890 ENOG4108ZHJ Organic hydroperoxide resistance protein EA674_015895 ENOG4107QHF type ii secretion system protein e EA674_015915 ENOG4105C2M dna polymerase I EA674_015920 ENOG4108VIA integral membrane protein EA674_015925 ENOG4105II7 pyrroline-5-carboxylate reductase EA674_015930 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) EA674_015940 ENOG4105C9X ppx gppa phosphatase EA674_015950 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) EA674_015970 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) EA674_015995 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) EA674_016010 ENOG4105W39 Membrane EA674_016015 ENOG4105CYM Glutathione S-transferase EA674_016035 ENOG4105CEY Amp-dependent synthetase and ligase EA674_016040 ENOG4105N42 UPF0307 protein EA674_016045 ENOG41080Z8 PHOSPHOCARRIER protein EA674_016065 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase EA674_016070 ENOG4105DJ0 Poly(A) Polymerase EA674_016075 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein EA674_016080 ENOG4105DXN mazG family EA674_016090 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) EA674_016105 ENOG4105C6T cysteine synthase EA674_016110 ENOG4105BZU Histidine kinase EA674_016115 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase EA674_016120 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase EA674_016125 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) EA674_016140 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) EA674_016145 ENOG4105W8H transhydrogenase (subunit alpha EA674_016150 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) EA674_016155 ENOG4106UX7 integral membrane protein EA674_016170 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) EA674_016180 ENOG4107RSM transcriptional regulator EA674_016190 ENOG4105CUZ uba thif-type nad fad binding protein EA674_016200 ENOG4107QM5 aconitate hydratase EA674_016205 ENOG4105F8V Hydrolase, tatD family EA674_016220 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) EA674_016245 ENOG4105BZU Histidine kinase EA674_016255 ENOG4108ZP8 Acetolactate synthase small subunit EA674_016260 ENOG4105C7K acetolactate synthase EA674_016285 ENOG4105DJY efflux transporter, rnd family, mfp subunit EA674_016290 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) EA674_016295 ENOG4105ENJ RND efflux system, outer membrane lipoprotein EA674_016300 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH EA674_016310 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) EA674_016315 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) EA674_016325 ENOG4105VW4 glutaredoxin 3 EA674_016345 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) EA674_016350 ENOG4105C2D reductase EA674_016360 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) EA674_016390 ENOG4105C84 Histidine ammonia-lyase EA674_016405 ENOG4105CEY Amp-dependent synthetase and ligase EA674_016420 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) EA674_016440 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) EA674_016460 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) EA674_016480 ENOG4105WVQ Fe-S assembly protein IscX EA674_016495 ENOG4105CN1 protease EA674_016510 ENOG4106HB6 Alpha beta hydrolase EA674_016520 ENOG4105C26 Dehydrogenase EA674_016525 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family EA674_016530 ENOG4105C6Z Gluconate EA674_016535 ENOG4108UHU Aldolase EA674_016540 ENOG4105C01 Dihydroxy-acid dehydratase EA674_016545 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) EA674_016550 ENOG4108DNC Involved in acetate metabolism (By similarity) EA674_016555 ENOG4107GFK fumarate EA674_016575 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) EA674_016585 ENOG4108ESX Receptor EA674_016595 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) EA674_016605 ENOG4105DWV Homoserine O-trans-acetylase EA674_016705 ENOG4105CIY formyltetrahydrofolate deformylase EA674_016715 ENOG4107RGH Aldehyde dehydrogenase EA674_016720 ENOG4105KDC 50s ribosomal protein l28 EA674_016725 ENOG4105W0E 50S ribosomal protein L33 EA674_016730 ENOG4105CKD glutathione-regulated potassium-efflux system protein EA674_016750 ENOG4105VFU Rna-binding protein EA674_016755 ENOG4105C4R Atp-dependent dna helicase EA674_016770 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) EA674_016780 ENOG4105KVH Transcriptional regulator EA674_016790 ENOG41069P5 Protein slyX homolog EA674_016795 ENOG4105C5H ABC transporter EA674_016800 ENOG4105N14 lysine exporter protein LysE YggA EA674_016805 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase EA674_016815 ENOG4105CK2 sodium dicarboxylate symporter EA674_016870 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) EA674_016895 ENOG4105DUM transcriptional regulator, lysR family EA674_016920 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase EA674_016935 ENOG4108W5M transcriptional regulator EA674_016950 ENOG4105D29 Helix-turn-helix type 11 domain protein EA674_016955 ENOG4107XGZ Hydrolase EA674_016960 ENOG4105EI2 Pseudouridine synthase EA674_016970 ENOG4105C03 ribonuclease EA674_016990 ENOG4105CBN LysR family transcriptional regulator EA674_016995 ENOG4105EMU Dehydrogenase EA674_017000 ENOG4105CSA Coproporphyrinogen iii oxidase EA674_017010 ENOG4107QI1 Mate efflux family protein EA674_017020 ENOG4107T8P acyl-Coa dehydrogenase EA674_017065 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) EA674_017070 ENOG4105C5X domain protein EA674_017085 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) EA674_017095 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase EA674_017100 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) EA674_017105 ENOG4108JU5 Magnesium and cobalt efflux protein EA674_017110 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) EA674_017115 ENOG4108Z7R Chaperone CsaA EA674_017125 ENOG4108VAU general secretion pathway protein G EA674_017130 ENOG4105D7Q type ii secretion system EA674_017135 ENOG4105C25 Primosomal protein n' EA674_017140 ENOG4105CKD glutathione-regulated potassium-efflux system protein EA674_017145 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) EA674_017155 ENOG4105DVC DnaJ domain protein EA674_017160 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) EA674_017165 ENOG4107QUT magnesium and cobalt transport protein CorA EA674_017185 ENOG4107QYX exodeoxyribonuclease v alpha EA674_017190 ENOG4107QKA exodeoxyribonuclease V beta EA674_017195 ENOG4105DSY exodeoxyribonuclease V, gamma EA674_017205 ENOG4105CSR polyphosphate kinase 2 EA674_017215 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) EA674_017230 ENOG41061H0 Monooxygenase EA674_017235 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase EA674_017250 ENOG4105D65 subunit l EA674_017255 ENOG4108ZE9 Monovalent cation H antiporter subunit C EA674_017260 ENOG4107R4Z monovalent cation h antiporter subunit d EA674_017265 ENOG4105SC1 monovalent cation H antiporter subunit E EA674_017270 ENOG4105W4C monovalent cation H antiporter subunit F EA674_017275 ENOG4105KJM monovalent cation h antiporter subunit g EA674_017290 ENOG4105CHV Transcription elongation factor NusA EA674_017315 ENOG4107EJC Preprotein translocase subunit SecG EA674_017325 ENOG4107QHF type ii secretion system protein e EA674_017340 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) EA674_017350 ENOG4105C2N RNA methyltransferase TrmH family group 3 EA674_017365 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) EA674_017375 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) EA674_017405 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) EA674_017410 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase EA674_017480 ENOG4107ZXU DSBA oxidoreductase EA674_017495 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) EA674_017510 ENOG4105D3Y Na H antiporter EA674_017515 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) EA674_017565 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) EA674_017570 ENOG4105PM1 preprotein translocase subunit SecE EA674_017610 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) EA674_017615 ENOG4105TV9 FHA Domain-Containing protein EA674_017620 ENOG4105GVR general secretion pathway protein D EA674_017635 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS EA674_017660 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) EA674_017665 ENOG4108NEV two component transcriptional regulator, LytTR family EA674_017670 ENOG4108HRK Histidine kinase EA674_017685 ENOG4108UTW Plays a role in the regulation of phosphate uptake EA674_017690 ENOG4105DFG type I secretion outer membrane protein EA674_017695 ENOG4108RNG Permease of the drug metabolite transporter EA674_017720 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) EA674_017725 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters EA674_017730 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) EA674_017735 ENOG4105CNI cell division protein FtsW EA674_017750 ENOG4105CE1 Ferrous iron transport protein b EA674_017760 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EA674_017765 ENOG4105T95 Thiol disulfide interChange protein EA674_017770 ENOG4105D6E homoserine dehydrogenase EA674_017780 ENOG41061WM D-Alanyl-D-Alanine EA674_017790 ENOG4107TUY Histidine kinase EA674_017795 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EA674_017800 ENOG4105CN1 protease EA674_017805 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) EA674_017810 ENOG4108K5H permease YjgP YjgQ family protein EA674_017850 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) EA674_017860 ENOG4105BZU Histidine kinase EA674_017875 ENOG4105C0P Mg chelatase subunit ChlI EA674_017885 ENOG4108R0M Aminoglycoside EA674_017930 ENOG4105CHH sulfate transporter EA674_017985 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) EA674_018035 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EA674_018065 ENOG4105CHH sulfate transporter EA674_018100 ENOG4105C0P Mg chelatase subunit ChlI EA674_018105 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EA674_018115 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EA674_018125 ENOG4105EPF Outer membrane porin EA674_018130 ENOG4105F0N pyrophosphate phospho-hydrolase EA674_018145 ENOG4105CEY Amp-dependent synthetase and ligase EA674_018150 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EA674_018155 ENOG41079KZ Major Facilitator Superfamily EA674_018160 ENOG4105EN6 Membrane EA674_018170 ENOG4105EE5 Membrane protein terC EA674_018175 ENOG4108URH decarboxylase EA674_018190 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) EA674_018205 ENOG4105CCT upf0313 protein EA674_018225 ENOG4105CS1 NAD(P)H quinone oxidoreductase EA674_018235 ENOG4105C6T cysteine synthase EA674_018270 ENOG4105Y7M Transcriptional regulator, TetR family EA674_018305 ENOG4105C79 DNA protecting protein DprA EA674_018320 ENOG4108IND Tetr family transcriptional regulator EA674_018325 ENOG4107RTG Major Facilitator superfamily EA674_018335 ENOG4108V06 Glutathione peroxidase EA674_018375 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) EA674_018400 ENOG4105FDK ABC transporter EA674_018405 ENOG4105FAV ABC, transporter EA674_018415 ENOG4105EZR dyp-type peroxidase family protein EA674_018425 ENOG4107R1I NAD-dependent malic enzyme EA674_018450 ENOG4105EUB pirin domain protein EA674_018470 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) EA674_018475 ENOG4106MP8 UPF0754 membrane protein EA674_018480 ENOG4108VBZ doxx family EA674_018485 ENOG4105DQR SNARE associated Golgi EA674_018500 ENOG4107QJE Chromosome Partitioning Protein EA674_018510 ENOG4107PSF BolA-like protein EA674_018530 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) EA674_018555 ENOG4105C1G acyl-Coa dehydrogenase EA674_018580 ENOG4105CSH Transporter EA674_018585 ENOG4105E39 Enoyl-CoA hydratase EA674_018590 ENOG4105E39 Enoyl-CoA hydratase EA674_018595 ENOG4105C1G acyl-Coa dehydrogenase EA674_018605 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase EA674_018610 ENOG4105C26 Dehydrogenase EA674_018620 ENOG4105C85 amino acid EA674_018625 ENOG4105C85 amino acid EA674_018630 ENOG4105M4H endoribonuclease L-psp EA674_018645 ENOG4105EW9 transcriptional regulator AsnC family EA674_018670 ENOG4105D3G Pseudouridine synthase EA674_018685 ENOG4108IG5 Transcriptional regulator EA674_018735 ENOG4108I0Z Aconitate hydratase EA674_018740 ENOG4105BZN citrate synthase EA674_018745 ENOG4105CR4 methylisocitrate lyase EA674_018750 ENOG4105DRR Transcriptional regulator, GntR family EA674_018760 ENOG4105CGF Aromatic amino acid aminotransferase EA674_018765 ENOG4105CXG d-lactate dehydrogenase EA674_018775 ENOG41073TP transcriptional regulator EA674_018780 ENOG4105DAA L-lactate EA674_018785 ENOG4107QKV phosphomannomutase EA674_018790 ENOG4105CMR udp-glucose 4-epimerase EA674_018800 ENOG4105C6Y Udp-glucose 6-dehydrogenase EA674_018805 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase EA674_018815 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase EA674_018820 ENOG4107WZ3 Transferase EA674_018825 ENOG4105D3Q Sugar transferase EA674_018835 ENOG4105C6Y Udp-glucose 6-dehydrogenase EA674_018850 ENOG4105K64 Glycosyl transferase, family 2 EA674_018855 ENOG4108ZPC Polysaccharide pyruvyl transferase EA674_018865 ENOG4107QQG Dehydrogenase EA674_018870 ENOG4105DAY polysaccharide export protein EA674_018880 ENOG4105D75 Capsular exopolysaccharide family EA674_018885 ENOG4108V1T peptidylprolyl cis-trans isomerase EA674_018890 ENOG4108V1T peptidylprolyl cis-trans isomerase EA674_018895 ENOG4105CJR Integral membrane protein (MviN EA674_018900 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase EA674_018905 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase EA674_018915 ENOG4105HSS phospholipase C EA674_018940 ENOG41062JF Transcriptional regulator EA674_018955 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) EA674_018960 ENOG4105UBK short-chain dehydrogenase reductase EA674_018975 ENOG4107QZM n-acetylglutamate synthase EA674_018980 ENOG4105GVF (ABC) transporter EA674_018985 ENOG4105GVF (ABC) transporter EA674_018990 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) EA674_018995 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component EA674_019000 ENOG4108VM9 ABC, transporter EA674_019005 ENOG4108R86 Transcriptional regulator EA674_019010 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) EA674_019020 ENOG4105DTN riboflavin biosynthesis protein ribF EA674_019025 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) EA674_019035 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase EA674_019075 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) EA674_019130 ENOG4105CVE Lytic murein transglycosylase EA674_019135 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit EA674_019140 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) EA674_019155 ENOG4105DFU Cell wall formation (By similarity) EA674_019165 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase EA674_019170 ENOG4105DU1 integral membrane protein, terc EA674_019180 ENOG4106032 Glutathionylspermidine synthase EA674_019190 ENOG4107QUY Guanine deaminase EA674_019195 ENOG4108UGV hypoxanthine phosphoribosyltransferase EA674_019205 ENOG4105T95 Thiol disulfide interChange protein EA674_019210 ENOG4105PGM cation diffusion facilitator family transporter EA674_019225 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins EA674_019240 ENOG4105VG0 50S ribosomal protein l34 EA674_019295 ENOG4105KK6 nuclease EA674_019300 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS EA674_019360 ENOG4105FA0 parb-like partition protein EA674_019380 ENOG4105CDW Resistance protein EA674_019570 ENOG4105K5T PilT protein EA674_019605 ENOG4105T95 Thiol disulfide interChange protein EA674_019685 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)