locus-tag class description EA714_000010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) EA714_000020 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EA714_000030 ENOG4105DQR SNARE associated Golgi EA714_000035 ENOG4105C5H ABC transporter EA714_000040 ENOG4108821 RND type efflux pump EA714_000045 ENOG4108821 RND type efflux pump EA714_000050 ENOG4108821 RND type efflux pump EA714_000060 ENOG4105D74 hydrolase EA714_000065 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) EA714_000070 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) EA714_000115 ENOG4105C8J )-transporter EA714_000125 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B EA714_000155 ENOG4105C2W permease EA714_000165 ENOG4108IG5 Transcriptional regulator EA714_000170 ENOG4105DJY efflux transporter, rnd family, mfp subunit EA714_000205 ENOG4105F27 Major Facilitator EA714_000210 ENOG4105CV8 reductase EA714_000215 ENOG4105HEI LysR family (Transcriptional regulator EA714_000235 ENOG4105DQ4 alcohol dehydrogenase EA714_000240 ENOG4108R3E Dna-3-methyladenine glycosylase i EA714_000255 ENOG4105CEN a g-specific adenine glycosylase EA714_000275 ENOG4108ZZ3 UPF0260 protein EA714_000285 ENOG4105D1H recombination factor protein RarA EA714_000290 ENOG4105S64 Formate nitrite transporter EA714_000310 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EA714_000315 ENOG4108RWI nicotinamidase EA714_000320 ENOG4105C09 Bile acid EA714_000325 ENOG4107QI1 Mate efflux family protein EA714_000330 ENOG4105EWC Purine nucleoside phosphorylase EA714_000350 ENOG4108RXX maleylacetoacetate isomerase EA714_000360 ENOG4105C85 amino acid EA714_000370 ENOG4105CKI cobalamin synthesis protein EA714_000380 ENOG4105CZE histidine utilization repressor EA714_000385 ENOG41090B9 response to stress EA714_000400 ENOG4105C85 amino acid EA714_000410 ENOG41088SP formiminoglutamate hydrolase EA714_000430 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) EA714_000435 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) EA714_000445 ENOG4108ZAI phosphatidylglycerophosphatase a EA714_000450 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) EA714_000465 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) EA714_000505 ENOG4105KHC sulfurtransferase EA714_000535 ENOG4105BZU Histidine kinase EA714_000540 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EA714_000555 ENOG4107QJQ Mate efflux family protein EA714_000560 ENOG4105CHM Aminotransferase EA714_000565 ENOG4106BRA Membrane EA714_000580 ENOG4105D9M gamma-glutamylcysteine synthetase EA714_000590 ENOG4105CS6 Rhs element vgr protein EA714_000615 ENOG4105IPS esterase EA714_000620 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EA714_000625 ENOG4105EWI Short-chain dehydrogenase reductase Sdr EA714_000630 ENOG4108Z2U ureidoglycolate hydrolase EA714_000640 ENOG41061H0 Monooxygenase EA714_000655 ENOG41084YZ Hydrolase EA714_000685 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) EA714_000690 ENOG4105BZU Histidine kinase EA714_000705 ENOG4105KUZ arsenate reductase EA714_000710 ENOG4105CGK Exodeoxyribonuclease III EA714_000730 ENOG4105D7Z glutathione synthase EA714_000750 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) EA714_000755 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) EA714_000760 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) EA714_000775 ENOG41063SB peptidase EA714_000780 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) EA714_000785 ENOG4107QSN dihydrolipoamide acetyltransferase EA714_000800 ENOG4105E0K tonB-dependent siderophore receptor EA714_000815 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) EA714_000830 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) EA714_000850 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EA714_000855 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase EA714_000865 ENOG4105D64 Mechanosensitive ion channel EA714_000875 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) EA714_000880 ENOG4108W2Y isochorismatase EA714_000890 ENOG4105D5G Transposase EA714_000895 ENOG4105FBW Monooxygenase EA714_000900 ENOG4108UZX fmn reductase EA714_000915 ENOG4105BZU Histidine kinase EA714_000920 ENOG41062QD Membrane EA714_000925 ENOG4107QN1 sodium solute EA714_000935 ENOG4105C94 Transporter EA714_000945 ENOG4105BZU Histidine kinase EA714_000955 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) EA714_000960 ENOG4108WUH Transcriptional regulator, TetR family EA714_000965 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein EA714_000975 ENOG4105RA2 Membrane EA714_000980 ENOG4105DWF phosphomethylpyrimidine kinase EA714_000990 ENOG4107RDB Major Facilitator EA714_000995 ENOG4108UUM single-stranded DNA-binding protein EA714_001005 ENOG4108UMN azlc family EA714_001015 ENOG4105C85 amino acid EA714_001025 ENOG4108JPW Aminotransferase EA714_001030 ENOG4105C26 Dehydrogenase EA714_001040 ENOG4105CHJ isochorismatase hydrolase EA714_001045 ENOG4105EUB pirin domain protein EA714_001070 ENOG4105D94 Major Facilitator Superfamily EA714_001075 ENOG4106NZI LysR family Transcriptional regulator EA714_001095 ENOG4105CPC Aldo Keto reductase EA714_001100 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) EA714_001130 ENOG4105KVH Transcriptional regulator EA714_001140 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein EA714_001205 ENOG4105CUV Homoserine Kinase EA714_001220 ENOG41061CK Antibiotic biosynthesis monooxygenase EA714_001250 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) EA714_001280 ENOG4105CYC Transferase EA714_001290 ENOG4105E0F Histidine kinase EA714_001295 ENOG4105DPZ Two component transcriptional regulator (Winged helix family EA714_001305 ENOG4105CHH sulfate transporter EA714_001310 ENOG4105PDP Short chain dehydrogenase EA714_001320 ENOG4105C5H ABC transporter EA714_001405 ENOG4108IQI permease EA714_001430 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein EA714_001445 ENOG4105CJN penicillin-binding protein EA714_001450 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) EA714_001455 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) EA714_001470 ENOG4105DHI Methyltransferase EA714_001475 ENOG4108JQC penicillin-binding protein 1A EA714_001500 ENOG4105E4G Type IV pilus EA714_001520 ENOG4105CBC glutamate synthase EA714_001525 ENOG4105BZ8 glutamate synthase EA714_001535 ENOG4108V0P LemA family EA714_001540 ENOG4105HA9 of methanol dehydrogenase type EA714_001555 ENOG4108YSG O-Antigen polymerase EA714_001560 ENOG4108UQY Iron-storage protein EA714_001570 ENOG4105KME endoribonuclease L-psp EA714_001575 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) EA714_001590 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) EA714_001640 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) EA714_001655 ENOG4107IFA Lipase (EC 3.1.1.3) EA714_001660 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) EA714_001665 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) EA714_001690 ENOG4108JQ1 Dehydrogenase EA714_001695 ENOG4105CQB FAD linked oxidase domain protein EA714_001705 ENOG4105VRH Antibiotic biosynthesis monooxygenase EA714_001710 ENOG4105NF4 modulator of drug activity EA714_001720 ENOG4107QF7 multi-drug EA714_001725 ENOG4105EM2 membrane EA714_001730 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) EA714_001735 ENOG4105IPI Membrane EA714_001740 ENOG4107SKI cobyrinic Acid a,c-diamide synthase EA714_001770 ENOG4108IQI permease EA714_001775 ENOG4105D82 Glutamate dehydrogenase EA714_001780 ENOG4105C8Y Acetylornithine aminotransferase EA714_001790 ENOG4105C26 Dehydrogenase EA714_001815 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin EA714_001875 ENOG4105W87 Cbs domain EA714_001880 ENOG41067S9 phage shock protein C, PspC EA714_001890 ENOG4105CSU acyl-Coa dehydrogenase EA714_001905 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) EA714_001920 ENOG4105ECY inositol monophosphatase EA714_001925 ENOG4105C1J atp-dependent rna helicase EA714_001935 ENOG4105DHJ ABC, transporter EA714_001940 ENOG4105CY3 ABC transporter, permease EA714_001950 ENOG4105E3I toluene tolerance EA714_001960 ENOG4105D7N magnesium and cobalt transport protein CorA EA714_001965 ENOG4108URH decarboxylase EA714_001975 ENOG4105MJ2 Competence protein EA714_001980 ENOG4105CB5 ATP-dependent DNA helicase recG EA714_002000 ENOG4105C29 acyl-CoA thioesterase EA714_002005 ENOG4105CK2 sodium dicarboxylate symporter EA714_002020 ENOG4105KPV Transcriptional regulator EA714_002030 ENOG4105D7A ATP-binding protein EA714_002035 ENOG4105C28 cystathionine EA714_002040 ENOG41089BK Glutamine amido-transferase EA714_002150 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) EA714_002155 ENOG41067V7 50S ribosomal protein L36 EA714_002165 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) EA714_002190 ENOG4105C1G acyl-Coa dehydrogenase EA714_002225 ENOG4105VKU nucleicacid-binding protein EA714_002230 ENOG4105DGW oligopeptidase A EA714_002235 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) EA714_002280 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase EA714_002285 ENOG4108K2B transcriptional regulator EA714_002295 ENOG4107S2Z UPF0761 membrane protein EA714_002300 ENOG4105CS1 NAD(P)H quinone oxidoreductase EA714_002330 ENOG4105C9A Phoh family EA714_002340 ENOG4105E4C Lytic transglycosylase catalytic EA714_002370 ENOG4105D6S protein involved in catabolism of external DNA EA714_002375 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase EA714_002420 ENOG4105C1G acyl-Coa dehydrogenase EA714_002425 ENOG4108RZE Tetr family transcriptional regulator EA714_002440 ENOG4107QX3 carboxylase EA714_002445 ENOG4105C1G acyl-Coa dehydrogenase EA714_002465 ENOG4105KB2 stringent starvation protein b EA714_002470 ENOG4107MKT Stringent starvation protein a EA714_002475 ENOG4108UJD 30S ribosomal protein S9 EA714_002485 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) EA714_002490 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) EA714_002495 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) EA714_002515 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) EA714_002525 ENOG4107RZC phospholipase d EA714_002535 ENOG4105UYK outer membrane protein a EA714_002540 ENOG4108KHX Diguanylate cyclase EA714_002575 ENOG4107QN2 dihydrolipoyl dehydrogenase EA714_002585 ENOG4107QPB Beta-lactamase domain protein EA714_002590 ENOG4107U2T alpha beta EA714_002600 ENOG4105NAU thioesterase Superfamily protein EA714_002630 ENOG4105K9H YciI-like protein EA714_002640 ENOG4105DB7 PHP domain protein EA714_002645 ENOG4105FFC UPF0187 protein EA714_002655 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase EA714_002660 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) EA714_002665 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) EA714_002670 ENOG4105VIE preprotein translocase, subunit YajC EA714_002720 ENOG4105BZU Histidine kinase EA714_002725 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) EA714_002730 ENOG4105CM2 brancheD-chain amino acid aminotransferase EA714_002745 ENOG4107BJW polysaccharide deacetylase EA714_002755 ENOG4108PQP glycosyl transferase group 1 EA714_002795 ENOG4105UGU tonB-dependent Receptor EA714_002815 ENOG4108VY7 phosphate-starvation-inducible protein PsiE EA714_002820 ENOG4108K3A Glutathione S-transferase EA714_002825 ENOG4108R4R Iron-regulated virulence regulatory protein EA714_002830 ENOG4105CSU acyl-Coa dehydrogenase EA714_002835 ENOG4105CSU acyl-Coa dehydrogenase EA714_002845 ENOG4105EB3 Histidine kinase EA714_002850 ENOG4105E3W Two component transcriptional regulator (Winged helix family EA714_002855 ENOG4105CNG UPF0061 protein EA714_002875 ENOG4108WBT adenosyltransferase EA714_002890 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) EA714_002925 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase EA714_002945 ENOG4105D3R alkyl hydroperoxide reductase EA714_002960 ENOG4105CSH Transporter EA714_002965 ENOG4108UT2 hemolysin iii EA714_002995 ENOG4105CHU acetyl-coa acetyltransferase EA714_003000 ENOG4108R6W Transcriptional regulator, ARAC family EA714_003010 ENOG4105TW1 Carbohydrate-selective porin OprB EA714_003015 ENOG4105DZG Dehydrogenase EA714_003020 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) EA714_003040 ENOG4105CHU acetyl-coa acetyltransferase EA714_003050 ENOG4108WHA ompa motb domain protein EA714_003060 ENOG4105E0Y RtcB Protein EA714_003065 ENOG4108IQI permease EA714_003075 ENOG4105C2W permease EA714_003095 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) EA714_003105 ENOG4108VX5 3-methyladenine DNA glycosylase EA714_003110 ENOG4105CHB tonB-dependent Receptor EA714_003115 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EA714_003130 ENOG4105T95 Thiol disulfide interChange protein EA714_003135 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) EA714_003145 ENOG4105K78 MarR family Transcriptional regulator EA714_003150 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA EA714_003155 ENOG4105KWI UPF0339 protein EA714_003180 ENOG4108UNF response regulator EA714_003185 ENOG4105M3Z response regulator EA714_003190 ENOG4108ZGA chew protein EA714_003195 ENOG4105C8Q Methyl-accepting chemotaxis EA714_003200 ENOG4105CBS Chea signal transduction histidine kinase EA714_003215 ENOG4106HKS Entericidin EcnA/B family EA714_003225 ENOG4105WD1 Membrane EA714_003230 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein EA714_003270 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) EA714_003280 ENOG4105EM2 membrane EA714_003285 ENOG4105C2C drug resistance transporter, Bcr CflA EA714_003305 ENOG4105BZG amino acid carrier protein EA714_003310 ENOG4105D78 K07001 NTE family protein EA714_003315 ENOG4105C7B Threonine dehydratase EA714_003350 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) EA714_003360 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) EA714_003365 ENOG4105DFF Rod shape-determining protein mreb EA714_003370 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) EA714_003375 ENOG4105VQ7 Rod shape-determining protein MreD EA714_003380 ENOG4108Z03 MAF-like protein EA714_003385 ENOG4105C03 ribonuclease EA714_003395 ENOG4105D8T Acyltransferase EA714_003405 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein EA714_003415 ENOG4108X0B nad(p)h dehydrogenase (quinone) EA714_003440 ENOG4105CF7 AraC family transcriptional regulator EA714_003460 ENOG4105C85 amino acid EA714_003465 ENOG4105C7F AcnD-accessory protein PrpF EA714_003470 ENOG4105CTB Polyprenyl synthetase EA714_003475 ENOG4105MSB protein, conserved in bacteria EA714_003490 ENOG4105D78 K07001 NTE family protein EA714_003515 ENOG4105DIJ Phosphoethanolamine transferase EA714_003520 ENOG4105XJC Two component transcriptional regulator (Winged helix family EA714_003525 ENOG4105DHQ Histidine kinase EA714_003545 ENOG4108M0I Transcriptional regulator EA714_003565 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) EA714_003585 ENOG4105K8R UPF0145 protein EA714_003590 ENOG4105K8R UPF0145 protein EA714_003595 ENOG4105ENJ RND efflux system, outer membrane lipoprotein EA714_003600 ENOG4105BZS acriflavin resistance protein EA714_003605 ENOG4105C1P efflux transporter, rnd family, mfp subunit EA714_003610 ENOG410841Q phosphoesterase PA-phosphatase related protein EA714_003640 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) EA714_003655 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) EA714_003660 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) EA714_003665 ENOG4105KVH Transcriptional regulator EA714_003675 ENOG4105CUB amino acid EA714_003690 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) EA714_003695 ENOG41084BA UPF0250 protein EA714_003700 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EA714_003735 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit EA714_003740 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein EA714_003750 ENOG4105E33 succinate dehydrogenase EA714_003765 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 EA714_003770 ENOG4105C7S Dehydrogenase EA714_003775 ENOG4107QN2 dihydrolipoyl dehydrogenase EA714_003785 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha EA714_003795 ENOG4105CKW Inner membrane protein yedI EA714_003800 ENOG4105CGZ zinc metallopeptidase EA714_003805 ENOG4105EEQ Na H antiporter EA714_003840 ENOG4105PNM synthesis protein EA714_003855 ENOG41080TK Universal stress protein EA714_003870 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain EA714_003875 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain EA714_003890 ENOG4105HBR Rna-binding protein EA714_003900 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) EA714_003905 ENOG4105EEI dihydropteroate synthase EA714_003955 ENOG4105CSH Transporter EA714_003960 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) EA714_003965 ENOG4105C6V Glycerol-3-phosphate dehydrogenase EA714_003980 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) EA714_004000 ENOG41080IJ Diacylglycerol kinase EA714_004010 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase EA714_004015 ENOG4105BZS acriflavin resistance protein EA714_004030 ENOG4105E4C Lytic transglycosylase catalytic EA714_004055 ENOG4108RRZ Transcription elongation factor GreB EA714_004070 ENOG4105CEY Amp-dependent synthetase and ligase EA714_004115 ENOG4105BZW Glycerate kinase EA714_004120 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit EA714_004125 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) EA714_004140 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) EA714_004150 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) EA714_004155 ENOG4105C85 amino acid EA714_004165 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) EA714_004175 ENOG4105N14 lysine exporter protein LysE YggA EA714_004180 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EA714_004185 ENOG4105BZJ Electron transfer flavoprotein EA714_004190 ENOG4105C10 Electron transfer flavoprotein EA714_004195 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EA714_004230 ENOG4107KET secretion protein, HlyD family EA714_004260 ENOG4105D60 lipoprotein releasing system transmembrane protein EA714_004265 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) EA714_004270 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 EA714_004280 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) EA714_004285 ENOG4107R6F Alpha Beta Hydrolase Fold protein EA714_004290 ENOG4108V3E phosphoribosylglycinamide formyltransferase EA714_004300 ENOG4105C02 permease EA714_004350 ENOG4105KCK Peptidoglycan-associated lipoprotein EA714_004355 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) EA714_004365 ENOG4105M8F Biopolymer transport protein exbD tolR EA714_004370 ENOG4105E02 MotA TolQ exbB proton channel EA714_004375 ENOG4107YD3 Thioesterase EA714_004380 ENOG4105CH2 amidohydrolase EA714_004400 ENOG4108ETH Formylglycinamide ribotide synthetase EA714_004405 ENOG4105C2C drug resistance transporter, Bcr CflA EA714_004410 ENOG4105EGD dinuclear metal center protein, YbgI family EA714_004415 ENOG4108UKI Enoyl-CoA hydratase EA714_004430 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen EA714_004445 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) EA714_004450 ENOG4107VRB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) EA714_004475 ENOG4107R11 Transcriptional regulator EA714_004480 ENOG4108IJ6 ABC transporter EA714_004490 ENOG4108I5D sulfate abc transporter EA714_004500 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein EA714_004505 ENOG4105YAZ 4-amino-4-deoxychorismate lyase EA714_004510 ENOG4105HHA aminodeoxychorismate lyase EA714_004525 ENOG4108IYU L-aspartate oxidase EA714_004530 ENOG4105C0H protease EA714_004545 ENOG4105C3F Signal peptidase i EA714_004560 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) EA714_004570 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) EA714_004575 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) EA714_004580 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase EA714_004585 ENOG4105EMU Dehydrogenase EA714_004625 ENOG4105BZU Histidine kinase EA714_004635 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) EA714_004645 ENOG4105DTR rard protein EA714_004680 ENOG4107QS8 (LipO)protein EA714_005015 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) EA714_005020 ENOG4105EA8 2-Nitropropane dioxygenase EA714_005050 ENOG4107R8N Glycosyl transferase, family 2 EA714_005065 ENOG4105CVP deoxyribo-dipyrimidine photolyase EA714_005070 ENOG4108YZY peptidylprolyl cis-trans isomerase EA714_005075 ENOG4105CEP NADH dehydrogenase EA714_005090 ENOG4105E9K Isocitrate dehydrogenase EA714_005095 ENOG4108R99 pseudouridine synthase EA714_005120 ENOG4105CBP Major Facilitator EA714_005125 ENOG4105EGI Transcriptional regulator EA714_005130 ENOG4108ETY sodium dicarboxylate symporter EA714_005135 ENOG4105JAB phenazine biosynthesis protein, phzf family EA714_005165 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) EA714_005180 ENOG4105D3G Pseudouridine synthase EA714_005185 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) EA714_005200 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) EA714_005225 ENOG4108JPW Aminotransferase EA714_005230 ENOG4105DY8 decarboxylase EA714_005240 ENOG4105F7P transcriptional regulator AsnC family EA714_005245 ENOG4107RA9 decarboxylase EA714_005250 ENOG4105C85 amino acid EA714_005255 ENOG4105CVA phosphate EA714_005260 ENOG4105C8U phosphate abc transporter EA714_005270 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) EA714_005275 ENOG4105ERU peptidase EA714_005290 ENOG4107QTF adenylosuccinate lyase EA714_005310 ENOG4108Z0R Transferase EA714_005315 ENOG4105DZ1 carboxypeptidase EA714_005335 ENOG4108K5P (LipO)protein EA714_005340 ENOG4105EJC lysr family transcriptional regulator EA714_005345 ENOG4105DAN ATP-dependent protease EA714_005360 ENOG4105DHU Bile acid EA714_005380 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein EA714_005390 ENOG4105D22 carbon starvation protein EA714_005395 ENOG4105VCD cytoplasmic protein EA714_005430 ENOG4108K8K Transcriptional regulator EA714_005445 ENOG4105C26 Dehydrogenase EA714_005450 ENOG4105C85 amino acid EA714_005455 ENOG4105ETT transcriptional Regulator, LysR family EA714_005460 ENOG4105C94 Transporter EA714_005465 ENOG4105C94 Transporter EA714_005475 ENOG4105C26 Dehydrogenase EA714_005480 ENOG4107QZF nitrite reductase NADPH large subunit EA714_005485 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) EA714_005515 ENOG41060M8 Pfam:PhdYeFM EA714_005520 ENOG4107QNK )-transporter EA714_005525 ENOG4107WEA mandelate racemase muconate lactonizing EA714_005535 ENOG4105J7D transcriptional regulator EA714_005555 ENOG4105C2I pirin domain protein EA714_005565 ENOG4105WWK YheO domain protein EA714_005580 ENOG4105CEY Amp-dependent synthetase and ligase EA714_005595 ENOG4108IPW abc transporter atp-binding protein EA714_005615 ENOG4105C0W non-ribosomal peptide synthetase EA714_005620 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase EA714_005625 ENOG4105WQI isochorismatase EA714_005640 ENOG4105BZ1 (ABC) transporter EA714_005660 ENOG4105E4F Isochorismate synthase EA714_005675 ENOG4105NX3 Membrane EA714_005695 ENOG4105EUJ GTP cyclohydrolase i EA714_005705 ENOG4105C7W Xanthine dehydrogenase EA714_005735 ENOG4105CD8 aminopeptidase N EA714_005740 ENOG4105DDQ anthranilate synthase EA714_005750 ENOG4105DUX Transporter EA714_005755 ENOG4105C5F glutamine synthetase EA714_005765 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) EA714_005800 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) EA714_005805 ENOG4107QNR UPF0135 protein EA714_005810 ENOG4105C0H protease EA714_005820 ENOG4105C6K Malic enzyme EA714_005825 ENOG4105BZU Histidine kinase EA714_005830 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) EA714_005835 ENOG4105SYT Methylenetetrahydrofolate reductase EA714_005840 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) EA714_005855 ENOG4107QPN acyl-Coa dehydrogenase EA714_005860 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) EA714_005865 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) EA714_005875 ENOG4107RNU major facilitator superfamily MFS_1 EA714_005885 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) EA714_005890 ENOG4105CE9 30S ribosomal protein S2 EA714_005930 ENOG4105CVE Lytic murein transglycosylase EA714_005935 ENOG4105CNI cell division protein FtsW EA714_005950 ENOG4105E3A (ABC) transporter EA714_005955 ENOG4105DA5 (ABC) transporter EA714_005990 ENOG4105ENJ RND efflux system, outer membrane lipoprotein EA714_006000 ENOG4105ENT Efflux transporter rnd family, mfp subunit EA714_006025 ENOG4105DSP amino acid AbC transporter EA714_006030 ENOG4106YG3 ABC transporter EA714_006035 ENOG4108JEH abc transporter atp-binding protein EA714_006045 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding EA714_006050 ENOG4105CFP Peptidase U32 EA714_006055 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EA714_006060 ENOG4105JAB phenazine biosynthesis protein, phzf family EA714_006065 ENOG4105DP0 ferredoxin-NADP reductase EA714_006070 ENOG4108R96 Methyltransferase, YaeB family EA714_006080 ENOG4107QHF type ii secretion system protein e EA714_006090 ENOG4105XJC Two component transcriptional regulator (Winged helix family EA714_006095 ENOG4105DHQ Histidine kinase EA714_006105 ENOG4105M6F mutator MutT protein EA714_006115 ENOG4105BZ4 penicillin-binding protein EA714_006120 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) EA714_006125 ENOG4105VUT cytoplasmic protein EA714_006130 ENOG4107QYG anthranilate phosphoribosyltransferase EA714_006140 ENOG4105CK2 sodium dicarboxylate symporter EA714_006145 ENOG4105C1G acyl-Coa dehydrogenase EA714_006150 ENOG4105NIV Esterase EA714_006155 ENOG4105CQC Prephenate dehydratase EA714_006160 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase EA714_006170 ENOG4105CIN aminoacyl-histidine dipeptidase EA714_006175 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) EA714_006205 ENOG4105M08 Membrane EA714_006210 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EA714_006220 ENOG4105VEQ Cold shock protein EA714_006225 ENOG4105C1J atp-dependent rna helicase EA714_006235 ENOG41069NU Nitroreductase EA714_006270 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase EA714_006285 ENOG4105C5I Dehydrogenase EA714_006290 ENOG4105ERG peptidase m48, ste24p EA714_006295 ENOG4105KTH gatB Yqey EA714_006300 ENOG4105VCC 30S ribosomal protein S21 EA714_006325 ENOG4105D9P serine threonine protein kinase EA714_006350 ENOG4105EVZ LysR family transcriptional regulator EA714_006355 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) EA714_006360 ENOG4105C26 Dehydrogenase EA714_006395 ENOG4105H4F exported protein EA714_006425 ENOG4105D6U Sodium Glutamate Symporter EA714_006435 ENOG4105JXH GntR family transcriptional regulator EA714_006485 ENOG4105CSH Transporter EA714_006510 ENOG4105CEB Aspartate aminotransferase EA714_006525 ENOG4105F1S paraquat-inducible protein a EA714_006530 ENOG4105DY2 Paraquat-inducible protein b EA714_006570 ENOG4105CK2 sodium dicarboxylate symporter EA714_006580 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) EA714_006585 ENOG4108UMI ABC transporter, permease EA714_006590 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) EA714_006600 ENOG4105C12 Phosphoribosylglycinamide synthetase EA714_006605 ENOG4105DC1 bifunctional purine biosynthesis protein purh EA714_006610 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) EA714_006660 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) EA714_006665 ENOG4105CDU Replicative dna helicase EA714_006690 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) EA714_006695 ENOG4105CCU oxidase (Subunit III) EA714_006700 ENOG4105BZ9 Cytochrome C oxidase, subunit I EA714_006705 ENOG4105E2S oxidase) subunit II EA714_006730 ENOG4107BJW polysaccharide deacetylase EA714_006735 ENOG4105CND Glycosyl transferase, family 2 EA714_006740 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD EA714_006750 ENOG4105DEN Luciferase family EA714_006770 ENOG4105CC0 LysR family Transcriptional regulator EA714_006785 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) EA714_006790 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component EA714_006795 ENOG4105GVF (ABC) transporter EA714_006810 ENOG4105C1G acyl-Coa dehydrogenase EA714_006820 ENOG4108MEJ flavin reductase domain protein EA714_006825 ENOG4105D06 uba thif-type nad fad binding protein EA714_006845 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) EA714_006850 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) EA714_006860 ENOG4105C08 Histidine kinase EA714_006865 ENOG4105EEX Two component transcriptional regulator (Winged helix family EA714_006870 ENOG4105CFQ glutamine synthetase EA714_006885 ENOG4107S74 Lysophospholipid transporter LplT EA714_006890 ENOG4105CFU surface antigen EA714_006910 ENOG4107QIJ Aconitate hydratase 2 EA714_006920 ENOG4105EYW Ion transport protein EA714_006925 ENOG4105F27 Major Facilitator EA714_006940 ENOG4105DZ2 Transcriptional regulator EA714_006975 ENOG4105K8N protein family UPF0079, ATPase EA714_006980 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) EA714_006990 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) EA714_006995 ENOG4108TZV Membrane EA714_007000 ENOG4108RCM Nitroreductase EA714_007010 ENOG4105F10 Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity) EA714_007025 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) EA714_007030 ENOG4107FQ9 ethanolamine ammonia-lyase EA714_007035 ENOG4105CPD ethanolamine ammonia-lyase EA714_007040 ENOG4107R55 ethanolamine transporter EA714_007050 ENOG4107RR1 TRANSCRIPTIONal EA714_007060 ENOG4105C0A alcohol dehydrogenase EA714_007065 ENOG4107QUV Domain protein EA714_007075 ENOG4105F4I Transcriptional regulator EA714_007095 ENOG4105CD8 aminopeptidase N EA714_007105 ENOG4105EMU Dehydrogenase EA714_007115 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) EA714_007120 ENOG4105EW9 transcriptional regulator AsnC family EA714_007135 ENOG4105R8C Transcriptional regulator EA714_007145 ENOG4105CUY Mechanosensitive ion channel EA714_007175 ENOG4105CNM Receptor EA714_007195 ENOG4105C5H ABC transporter EA714_007200 ENOG41081QV Universal stress protein EA714_007215 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic EA714_007225 ENOG4105DKK Benzoate EA714_007230 ENOG4105EW9 transcriptional regulator AsnC family EA714_007235 ENOG4108NIW Leucine export protein LeuE EA714_007240 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) EA714_007245 ENOG4105C5Q Transcriptional regulator EA714_007255 ENOG4105CHU acetyl-coa acetyltransferase EA714_007260 ENOG4105CHR reductase EA714_007285 ENOG4107QMP dna polymerase iii subunits gamma and tau EA714_007290 ENOG4105HSS phospholipase C EA714_007300 ENOG4105C0A alcohol dehydrogenase EA714_007330 ENOG4105CBC glutamate synthase EA714_007710 ENOG4105D8G Major Facilitator superfamily EA714_007720 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase EA714_007725 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein EA714_007750 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EA714_007760 ENOG4107QZF nitrite reductase NADPH large subunit EA714_007765 ENOG4108IFG nitrite reductase, (NAD(P)H) EA714_007785 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) EA714_007800 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) EA714_007805 ENOG4105CVM Molybdenum cofactor synthesis domain protein EA714_007815 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EA714_007820 ENOG4105T38 integral membrane protein EA714_007840 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) EA714_007845 ENOG4105CMR udp-glucose 4-epimerase EA714_007905 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EA714_007910 ENOG4105CUX Signal transduction histidine kinase EA714_007935 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) EA714_007940 ENOG4105KNE Phosphatidate cytidylyltransferase EA714_007950 ENOG4105DZP Membrane-associated zinc metalloprotease EA714_007975 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) EA714_007990 ENOG4105Y3E Modulates RecA activity (By similarity) EA714_008000 ENOG4105VEJ Heat shock protein EA714_008005 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 EA714_008030 ENOG4105F7P transcriptional regulator AsnC family EA714_008040 ENOG4105C85 amino acid EA714_008055 ENOG4105CHH sulfate transporter EA714_008085 ENOG4105BZ1 (ABC) transporter EA714_008135 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) EA714_008200 ENOG4105D8V Glucose sorbosone dehydrogenase EA714_008210 ENOG4105BZU Histidine kinase EA714_008230 ENOG4105DM4 PTS System EA714_008235 ENOG4105DE4 1-phosphofructokinase EA714_008240 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) EA714_008265 ENOG4105CWM branched-chain amino acid transport system II carrier protein EA714_008270 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) EA714_008275 ENOG4105CC0 LysR family Transcriptional regulator EA714_008285 ENOG4105M2J Glutaredoxin EA714_008290 ENOG4105C8Y Acetylornithine aminotransferase EA714_008295 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) EA714_008320 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) EA714_008330 ENOG41068P6 UPF0319 protein EA714_008350 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii EA714_008355 ENOG4105C4M (Ubiquinol oxidase) subunit I EA714_008365 ENOG4105PV3 Inner membrane protein yqiJ EA714_008380 ENOG4105E0K tonB-dependent siderophore receptor EA714_008390 ENOG4105HDD phospholipase EA714_008395 ENOG4105CZN Potassium uptake protein EA714_008405 ENOG4105C7B Threonine dehydratase EA714_008435 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) EA714_008440 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EA714_008450 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) EA714_008465 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EA714_008510 ENOG4107VMU Membrane EA714_008515 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) EA714_008525 ENOG4107QP7 CoA-transferase subunit A EA714_008530 ENOG4107QNJ CoA-transferase subunit B EA714_008535 ENOG4105CHU acetyl-coa acetyltransferase EA714_008540 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase EA714_008545 ENOG4105F2Z 3-oxoadipate enol-lactonase EA714_008550 ENOG4105D2S major facilitator superfamily EA714_008555 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase EA714_008560 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta EA714_008565 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha EA714_008570 ENOG4105FF2 Type I DHQase EA714_008575 ENOG4106JPM 3-dehydroshikimate dehydratase EA714_008580 ENOG4105TW1 Carbohydrate-selective porin OprB EA714_008585 ENOG4105DZG Dehydrogenase EA714_008595 ENOG4105MD1 YeeE YedE family protein EA714_008610 ENOG4107HP6 Transcriptional regulator EA714_008615 ENOG4108PTX LysR family Transcriptional regulator EA714_008620 ENOG4105C1G acyl-Coa dehydrogenase EA714_008645 ENOG4105DNH Major Facilitator EA714_008655 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) EA714_008675 ENOG4105FUY alpha subunit EA714_008685 ENOG4105CHR reductase EA714_008705 ENOG4105F11 amine oxidase EA714_008715 ENOG4105C26 Dehydrogenase EA714_008725 ENOG4105F2Z 3-oxoadipate enol-lactonase EA714_008730 ENOG4105CHU acetyl-coa acetyltransferase EA714_008735 ENOG4107QNJ CoA-transferase subunit B EA714_008740 ENOG4107QP7 CoA-transferase subunit A EA714_008750 ENOG4105NN7 muconolactone delta-isomerase EA714_008755 ENOG4105DTQ mandelate racemase muconate lactonizing EA714_008760 ENOG4108KB2 LysR family Transcriptional regulator EA714_008770 ENOG4107EJG GntR family transcriptional regulator EA714_008790 ENOG4105CZJ Aldehyde dehydrogenase EA714_008810 ENOG4105C1G acyl-Coa dehydrogenase EA714_008815 ENOG4105CHR reductase EA714_008820 ENOG4108JU7 Transcriptional regulator EA714_008830 ENOG41062QD Membrane EA714_008845 ENOG4107RGH Aldehyde dehydrogenase EA714_008860 ENOG4105CH6 catalase EA714_008885 ENOG4105K56 Transcriptional regulator EA714_008890 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EA714_008900 ENOG4105NAE bifunctional deaminase-reductase domain protein EA714_008930 ENOG4107Z3H Transcriptional regulator, TetR family EA714_008940 ENOG4105CHJ isochorismatase hydrolase EA714_008950 ENOG4105EJC lysr family transcriptional regulator EA714_008955 ENOG4105D8V Glucose sorbosone dehydrogenase EA714_008960 ENOG4105CKD glutathione-regulated potassium-efflux system protein EA714_008970 ENOG4105CH2 amidohydrolase EA714_008985 ENOG4105D5K Hemolysin activator protein EA714_008990 ENOG4105CKT filamentous hemagglutinin EA714_009020 ENOG4105FDP GntR family transcriptional regulator EA714_009035 ENOG4106KR7 LysR family Transcriptional regulator EA714_009060 ENOG4108JQ1 Dehydrogenase EA714_009065 ENOG4105JSC dimethylmenaquinone methyltransferase EA714_009085 ENOG4105CW7 secretion protein, HlyD family EA714_009100 ENOG4105CZJ Aldehyde dehydrogenase EA714_009105 ENOG4105C01 Dihydroxy-acid dehydratase EA714_009115 ENOG4105DDW LysR family Transcriptional regulator EA714_009120 ENOG4105EXW epimerase dehydratase EA714_009130 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase EA714_009135 ENOG4105CF7 AraC family transcriptional regulator EA714_009150 ENOG4105DQ4 alcohol dehydrogenase EA714_009160 ENOG4105EHG Permease protein EA714_009165 ENOG4105E0A ABC, transporter EA714_009185 ENOG4105C5T Phosphoribosyl pyrophosphate synthase EA714_009265 ENOG4108UAJ Transcriptional regulator EA714_009305 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) EA714_009360 ENOG4108BAS reductase EA714_009375 ENOG4108R6W Transcriptional regulator, ARAC family EA714_009380 ENOG4108821 RND type efflux pump EA714_009385 ENOG4105E0F Histidine kinase EA714_009390 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EA714_009395 ENOG4105C1P efflux transporter, rnd family, mfp subunit EA714_009400 ENOG4105BZS acriflavin resistance protein EA714_009405 ENOG4105ENJ RND efflux system, outer membrane lipoprotein EA714_009415 ENOG4105CT3 Monooxygenase EA714_009435 ENOG4105CJP fad dependent oxidoreductase EA714_009455 ENOG4105X0I Fimbrial EA714_009510 ENOG4107RZC phospholipase d EA714_009530 ENOG4108IGT Dipeptidase EA714_009565 ENOG4107T31 5'-nucleotidase EA714_009575 ENOG4105WQI isochorismatase EA714_009580 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase EA714_009585 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) EA714_009590 ENOG4105E0C molybdate abc transporter EA714_009595 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein EA714_009600 ENOG4105F4R Transcriptional regulator mode EA714_009605 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit EA714_009610 ENOG4108YS2 small subunit EA714_009615 ENOG4105F57 Anthranilate dioxygenase reductase EA714_009640 ENOG4105CHR reductase EA714_009650 ENOG4105D2S major facilitator superfamily EA714_009655 ENOG4105CF7 AraC family transcriptional regulator EA714_009665 ENOG4105DTD Dehydrogenase EA714_009670 ENOG4105CY2 Citrate transporter EA714_009680 ENOG4108M0I Transcriptional regulator EA714_009690 ENOG4107QNJ CoA-transferase subunit B EA714_009695 ENOG4105CRW Short chain fatty acid transporter EA714_009700 ENOG4105CHU acetyl-coa acetyltransferase EA714_009710 ENOG4107YNJ LysR family Transcriptional regulator EA714_009725 ENOG4108IJ0 Aspartate ammonia-lyase EA714_009735 ENOG4105CSH Transporter EA714_009755 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component EA714_009760 ENOG4106FTQ Taurine ABC transporter, periplasmic EA714_009775 ENOG4105FDP GntR family transcriptional regulator EA714_009785 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) EA714_009790 ENOG4105KVH Transcriptional regulator EA714_009795 ENOG4105UEI Transcriptional Regulator AraC Family EA714_009810 ENOG4108VCT Sulfite exporter TauE/SafE EA714_009820 ENOG4107QPB Beta-lactamase domain protein EA714_009830 ENOG4105FFC UPF0187 protein EA714_009840 ENOG4105CHR reductase EA714_009855 ENOG4105CPP Dehydrogenase, E1 component EA714_009860 ENOG4107R0V Pyruvate dehydrogenase EA714_009865 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) EA714_009880 ENOG4105BZU Histidine kinase EA714_009890 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) EA714_009895 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) EA714_009940 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) EA714_009955 ENOG4105C28 cystathionine EA714_009965 ENOG4105F2W methyltransferase EA714_009995 ENOG4105K59 histidine triad (HIT) protein EA714_010020 ENOG4107QWP ABC-2 type transporter EA714_010025 ENOG4107QWP ABC-2 type transporter EA714_010030 ENOG4105CJ1 ABC, transporter EA714_010045 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) EA714_010050 ENOG4105CNM Receptor EA714_010070 ENOG4107TSN permease EA714_010075 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) EA714_010095 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) EA714_010100 ENOG4108YZT Adenosylcobinamide kinase EA714_010155 ENOG4105DJU Siderophore biosynthesis protein EA714_010160 ENOG4105DUU IucA IucC family protein EA714_010180 ENOG4108Z66 YbaK ebsC protein EA714_010195 ENOG4105C1G acyl-Coa dehydrogenase EA714_010200 ENOG4105C1G acyl-Coa dehydrogenase EA714_010205 ENOG4105EEF Alkane 1-monooxygenase EA714_010210 ENOG4105E7U AraC family transcriptional regulator EA714_010215 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) EA714_010220 ENOG4105K70 DNA-binding protein EA714_010235 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family EA714_010245 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins EA714_010250 ENOG4108Z4V iron-sulfur cluster assembly EA714_010265 ENOG4108ZIT Ferredoxin, 2FE-2S EA714_010270 ENOG4105F8J Adenylate Guanylate cyclase EA714_010280 ENOG4108JA2 transcriptioN-repair coupling factor EA714_010300 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) EA714_010305 ENOG4105K4T epimerase EA714_010320 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase EA714_010340 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component EA714_010350 ENOG4105DGW oligopeptidase A EA714_010390 ENOG4105SG9 biopolymer transport protein, ExbD EA714_010400 ENOG4107QP3 malate synthase g EA714_010405 ENOG4105D6Z AFG1 family ATPase EA714_010415 ENOG4107RN6 Monooxygenase EA714_010435 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) EA714_010440 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) EA714_010455 ENOG4108Z6B deaminase EA714_010475 ENOG4108RTD type II secretion system protein K EA714_010500 ENOG4105F8V Hydrolase, tatD family EA714_010510 ENOG4107QRG dna polymerase iii EA714_010520 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) EA714_010525 ENOG4105BZ1 (ABC) transporter EA714_010540 ENOG4105FA0 parb-like partition protein EA714_010545 ENOG4107QJE Chromosome Partitioning Protein EA714_010555 ENOG4108S0S Nucleotidyl transferase EA714_010560 ENOG4105EHM Aminoglycoside phosphotransferase EA714_010565 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) EA714_010570 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) EA714_010575 ENOG4105D2N Aldolase EA714_010595 ENOG4108UHJ MAF-like protein EA714_010600 ENOG4105EZE Cupin 4 family protein EA714_010610 ENOG41080HT Transcriptional regulator, arsr family EA714_010620 ENOG4105XPP Protein of unknown function (DUF1275) EA714_010625 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme EA714_010630 ENOG4105BZ1 (ABC) transporter EA714_010640 ENOG4108ZX5 transcriptional regulator EA714_010650 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) EA714_010655 ENOG4105CK7 Sodium proline symporter EA714_010660 ENOG4105EW9 transcriptional regulator AsnC family EA714_010665 ENOG4105C26 Dehydrogenase EA714_010670 ENOG4105YGK Pfam:UPF0157 EA714_010685 ENOG4108T58 Mg2 transport protein CorA EA714_010695 ENOG4108YYC ycei family EA714_010705 ENOG4105CV1 Transketolase (EC 2.2.1.1) EA714_010735 ENOG4108HWY Beta-lactamase EA714_010755 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) EA714_010760 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) EA714_010780 ENOG4105X0I Fimbrial EA714_010785 ENOG4105GQR Chaperone EA714_010815 ENOG4108IPJ Membrane EA714_010825 ENOG4105ETS cytosine purines uracil thiamine allantoin EA714_010835 ENOG4105CC0 LysR family Transcriptional regulator EA714_010855 ENOG41067SE Tetr family transcriptional regulator EA714_010870 ENOG4105EW9 transcriptional regulator AsnC family EA714_010880 ENOG4105CDA abc transporter atp-binding protein EA714_010885 ENOG4105DRP amino acid AbC transporter EA714_010890 ENOG4105EAD ABC transporter EA714_010905 ENOG4107T8P acyl-Coa dehydrogenase EA714_010920 ENOG4105D01 (LipO)protein EA714_010925 ENOG4105D01 (LipO)protein EA714_010930 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) EA714_010935 ENOG4108UMI ABC transporter, permease EA714_010940 ENOG4105C3G gtp-binding protein EA714_010965 ENOG4108UMN azlc family EA714_010970 ENOG4105ZED uncharacterized protein ygaH EA714_011000 ENOG4105E7U AraC family transcriptional regulator EA714_011005 ENOG4108V06 Glutathione peroxidase EA714_011015 ENOG4105CHM Aminotransferase EA714_011030 ENOG4105C0B DNA polymerase III (alpha subunit) EA714_011055 ENOG4108JU3 Alkyl hydroperoxide reductase EA714_011070 ENOG4108KB2 LysR family Transcriptional regulator EA714_011075 ENOG4105D6J arsenicaL-resistance protein EA714_011080 ENOG41082YX Transcriptional regulator, arsr family EA714_011095 ENOG4105CPN adenine deaminase EA714_011105 ENOG4105CBN LysR family transcriptional regulator EA714_011115 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease EA714_011125 ENOG4105E2B Taurine dioxygenase EA714_011130 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component EA714_011135 ENOG4108IY8 ABC, transporter EA714_011140 ENOG4106FTQ Taurine ABC transporter, periplasmic EA714_011160 ENOG4105C54 Major Facilitator superfamily EA714_011185 ENOG4105C4M (Ubiquinol oxidase) subunit I EA714_011190 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii EA714_011200 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EA714_011205 ENOG4108K70 Transcriptional regulator EA714_011220 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase EA714_011225 ENOG4105PSI phosphoribosyl-dephospho-CoA transferase EA714_011240 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) EA714_011245 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase EA714_011255 ENOG4105DXI Major Facilitator superfamily EA714_011275 ENOG41067MG lrgb family EA714_011280 ENOG4105VAW lrga family EA714_011285 ENOG4105CMU LysR family (Transcriptional regulator EA714_011290 ENOG4108SHQ Glutathione S-transferase EA714_011295 ENOG4105CYM Glutathione S-transferase EA714_011300 ENOG4105CBN LysR family transcriptional regulator EA714_011305 ENOG4105CHR reductase EA714_011315 ENOG4105D7W serine acetyltransferase EA714_011320 ENOG4105ESN nucleotide-binding protein EA714_011325 ENOG4105C9B Cysteine desulfurase EA714_011340 ENOG4105EXG Transcriptional regulator EA714_011350 ENOG4105CT1 (ABC) transporter EA714_011355 ENOG4107RP9 extracellular solute-binding protein, family 3 EA714_011360 ENOG4105CDA abc transporter atp-binding protein EA714_011365 ENOG4108HW4 amino acid AbC transporter EA714_011370 ENOG4105EAD ABC transporter EA714_011385 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase EA714_011390 ENOG4105BZU Histidine kinase EA714_011400 ENOG4105EW9 transcriptional regulator AsnC family EA714_011410 ENOG4105KT5 UmuD protein EA714_011430 ENOG4105CYX Short-chain dehydrogenase reductase Sdr EA714_011475 ENOG4105HEI LysR family (Transcriptional regulator EA714_011495 ENOG4105CEY Amp-dependent synthetase and ligase EA714_011500 ENOG4105R8C Transcriptional regulator EA714_011505 ENOG4105C1G acyl-Coa dehydrogenase EA714_011510 ENOG4107QX3 carboxylase EA714_011515 ENOG4105E39 Enoyl-CoA hydratase EA714_011530 ENOG4105CC0 LysR family Transcriptional regulator EA714_011545 ENOG4105CSU acyl-Coa dehydrogenase EA714_011555 ENOG4105EQ0 Major Facilitator superfamily EA714_011565 ENOG4107QNJ CoA-transferase subunit B EA714_011570 ENOG4107QP7 CoA-transferase subunit A EA714_011575 ENOG4107RGD Major Facilitator superfamily EA714_011580 ENOG4105C1G acyl-Coa dehydrogenase EA714_011585 ENOG4105E39 Enoyl-CoA hydratase EA714_011590 ENOG4105CHR reductase EA714_011595 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase EA714_011600 ENOG4105CHU acetyl-coa acetyltransferase EA714_011610 ENOG4105EQ0 Major Facilitator superfamily EA714_011615 ENOG4105EA8 2-Nitropropane dioxygenase EA714_011620 ENOG4108UKI Enoyl-CoA hydratase EA714_011635 ENOG4105C1G acyl-Coa dehydrogenase EA714_011640 ENOG4107RGD Major Facilitator superfamily EA714_011645 ENOG4108KAZ Involved in phosphonate degradation (By similarity) EA714_011650 ENOG4107STF Involved in phosphonate degradation (By similarity) EA714_011660 ENOG4107RCV ABC transporter, permease EA714_011665 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) EA714_011670 ENOG4105C4Y ABC transporter EA714_011680 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase EA714_011685 ENOG4107HP6 Transcriptional regulator EA714_011695 ENOG4105HEI LysR family (Transcriptional regulator EA714_011700 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase EA714_011705 ENOG4105C26 Dehydrogenase EA714_011715 ENOG4105ETS cytosine purines uracil thiamine allantoin EA714_011725 ENOG4105C26 Dehydrogenase EA714_011730 ENOG4108M8W Monooxygenase EA714_011735 ENOG4105MXW flavin reductase domain protein, FMN-binding EA714_011740 ENOG4108MXF Alpha Beta Hydrolase EA714_011760 ENOG4105CPW cytochrome b561 EA714_011765 ENOG4107VGR Catalase EA714_011805 ENOG4107YAU phenylacetic acid degradation protein EA714_011815 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein EA714_011820 ENOG4105DZS Phenylacetate-CoA ligase EA714_011825 ENOG4105CHU acetyl-coa acetyltransferase EA714_011830 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase EA714_011835 ENOG4108UKI Enoyl-CoA hydratase EA714_011840 ENOG4105E39 Enoyl-CoA hydratase EA714_011845 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) EA714_011850 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit EA714_011855 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit EA714_011860 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit EA714_011865 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit EA714_011870 ENOG4105DXM phenylacetic acid degradation protein EA714_011875 ENOG4105EJQ L-serine dehydratase EA714_011880 ENOG4107QTZ amino acid EA714_011885 ENOG4105CZJ Aldehyde dehydrogenase EA714_011910 ENOG4105MWK D-amino acid dehydrogenase, small subunit EA714_011930 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EA714_011945 ENOG4108Z4X TRANSCRIPTIONal EA714_011960 ENOG4105WPN DNA integration recombination invertion protein EA714_011975 ENOG4105DJ2 Major Facilitator Superfamily EA714_011980 ENOG4107Y2X deaminase EA714_011990 ENOG4105EMY transcriptional regulator EA714_012020 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EA714_012030 ENOG4105UYK outer membrane protein a EA714_012105 ENOG4108HW3 (ABC) transporter EA714_012115 ENOG4105MRR Transcriptional regulator (By similarity) EA714_012135 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF EA714_012140 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase EA714_012155 ENOG4105E2A Dehydrogenase EA714_012165 ENOG4105R8C Transcriptional regulator EA714_012190 ENOG4107R4J Chloride channel EA714_012195 ENOG4108JIK carboxylase EA714_012215 ENOG4105C5A transporter EA714_012220 ENOG4108WAV Transcriptional regulator EA714_012235 ENOG4105CNA YD repeat protein EA714_012275 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) EA714_012295 ENOG4105D2S major facilitator superfamily EA714_012310 ENOG4105D1S lipid A biosynthesis EA714_012315 ENOG4105BZU Histidine kinase EA714_012320 ENOG4107AQZ Membrane EA714_012340 ENOG4108Z4U Ferredoxin EA714_012380 ENOG4105DFG type I secretion outer membrane protein EA714_012385 ENOG4108IUZ ABC transporter EA714_012390 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA EA714_012400 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase EA714_012405 ENOG4105C2X Arabinose 5-phosphate isomerase EA714_012440 ENOG4107YPT transcriptional regulator EA714_012475 ENOG4105II7 pyrroline-5-carboxylate reductase EA714_012485 ENOG4105VEQ Cold shock protein EA714_012490 ENOG410829K Lysine exporter protein (Lyse ygga) EA714_012525 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) EA714_012580 ENOG4108KB2 LysR family Transcriptional regulator EA714_012585 ENOG4105FUY alpha subunit EA714_012590 ENOG4108UKV benzoate 1,2-dioxygenase EA714_012595 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein EA714_012600 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase EA714_012605 ENOG4105DKK Benzoate EA714_012610 ENOG4105D2S major facilitator superfamily EA714_012625 ENOG4105CQ7 ATP-dependent helicase EA714_012630 ENOG4105D3R alkyl hydroperoxide reductase EA714_012640 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) EA714_012650 ENOG4108JU3 Alkyl hydroperoxide reductase EA714_012660 ENOG4108K3A Glutathione S-transferase EA714_012670 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) EA714_012675 ENOG4108TGY Glutathione S-transferase EA714_012685 ENOG4108ZG0 Ompa motb domain protein EA714_012690 ENOG4105CD3 dihydroorotase EA714_012720 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EA714_012735 ENOG4108UKZ OsmC family EA714_012740 ENOG4107RYR Transcriptional regulator, Crp Fnr family EA714_012745 ENOG4105CPC Aldo Keto reductase EA714_012760 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis EA714_012770 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase EA714_012780 ENOG4105CFH Aspartokinase EA714_012790 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) EA714_012800 ENOG4105CPW cytochrome b561 EA714_012805 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) EA714_012840 ENOG4105D01 (LipO)protein EA714_012845 ENOG4108M3P Membrane EA714_012860 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EA714_012880 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) EA714_012900 ENOG4108JQ5 ABC transporter EA714_012905 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component EA714_012910 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component EA714_012920 ENOG4105E9H Lytic Murein transglycosylase EA714_012920 ENOG4105E9H Lytic Murein transglycosylase EA714_012925 ENOG4107RZZ dna polymerase iii epsilon subunit EA714_012935 ENOG4105E09 nadh pyrophosphatase EA714_012945 ENOG4105W4M Transport-associated protein EA714_012955 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) EA714_012965 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) EA714_012970 ENOG4108ZUB Lysine exporter protein (Lyse ygga) EA714_012990 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family EA714_012995 ENOG4105D0A hydroxylase EA714_013000 ENOG4107RAQ aminopeptidase EA714_013035 ENOG4105DIJ Phosphoethanolamine transferase EA714_013080 ENOG4105DR5 peptidase EA714_013405 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase EA714_013430 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b EA714_013440 ENOG4105D82 Glutamate dehydrogenase EA714_013445 ENOG4108R3D Electron transport complex EA714_013450 ENOG4105CSM endonuclease III EA714_013475 ENOG4105CJN penicillin-binding protein EA714_013480 ENOG4106H78 methyltransferase EA714_013495 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) EA714_013505 ENOG4105CQM Urea amidohydrolase subunit alpha EA714_013535 ENOG4107RET Isocitrate lyase EA714_013545 ENOG4105C37 (CBS) domain EA714_013555 ENOG4105D4T Citrate transporter EA714_013570 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) EA714_013585 ENOG4108MRJ EA714_013605 ENOG4105VCQ rubredoxin EA714_013610 ENOG4107QZF nitrite reductase NADPH large subunit EA714_013620 ENOG4105C5Q Transcriptional regulator EA714_013640 ENOG4107U91 Rhomboid family EA714_013645 ENOG4105CV6 ABC transporter, permease EA714_013650 ENOG4108I0Y (ABC) transporter EA714_013655 ENOG4108UJV acyl-CoA thioesterase i EA714_013675 ENOG4107RNH Outer membrane receptor FepA EA714_013690 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) EA714_013695 ENOG4105E6M Sulphatase-modifying factor protein EA714_013715 ENOG4105CJ3 phosphate transporter EA714_013720 ENOG4105C3R Methionine synthase EA714_013735 ENOG4105CSP Major Facilitator Superfamily EA714_013745 ENOG4108PZW LysR family Transcriptional regulator EA714_013760 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) EA714_013765 ENOG4105EU0 Major facilitator Superfamily EA714_013770 ENOG4108R6W Transcriptional regulator, ARAC family EA714_013775 ENOG4105CSV Glutaminase EA714_013780 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) EA714_013785 ENOG4105CSH Transporter EA714_013795 ENOG4105C7K acetolactate synthase EA714_013810 ENOG4105CHR reductase EA714_013815 ENOG4108MXF Alpha Beta Hydrolase EA714_013825 ENOG4105DJB Major Facilitator Superfamily EA714_013830 ENOG4108DNI pyridine nucleotide-disulfide oxidoreductase EA714_013840 ENOG4105CHR reductase EA714_013860 ENOG41069M3 Transcriptional regulator EA714_013875 ENOG4106YT9 Enoyl-CoA hydratase EA714_013885 ENOG4105CND Glycosyl transferase, family 2 EA714_013890 ENOG4107BJW polysaccharide deacetylase EA714_013900 ENOG4108VWS Yaeq family EA714_013910 ENOG4105CKI cobalamin synthesis protein EA714_013930 ENOG4105C94 Transporter EA714_013935 ENOG4105C94 Transporter EA714_013940 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) EA714_013965 ENOG4107QK5 Homocysteine s-methyltransferase EA714_013970 ENOG4105D5Q Arginine ornithine antiporter EA714_013995 ENOG4108YNN Heme oxygenase EA714_014025 ENOG4108SF5 RNA Polymerase EA714_014035 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EA714_014040 ENOG4105C54 Major Facilitator superfamily EA714_014165 ENOG4105DFP Integrase EA714_014175 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) EA714_014180 ENOG4105C0R drug resistance transporter emrb qaca subfamily EA714_014185 ENOG4105CW7 secretion protein, HlyD family EA714_014190 ENOG4108VUY thioesterase Superfamily protein EA714_014195 ENOG4105D52 delta-aminolevulinic acid dehydratase EA714_014200 ENOG4105MWK D-amino acid dehydrogenase, small subunit EA714_014205 ENOG4105ECP epimerase EA714_014225 ENOG4107RH8 nuclease SbcCD subunit D EA714_014230 ENOG4105EYH Exonuclease EA714_014235 ENOG4105DFA alanine racemase domain protein EA714_014240 ENOG4105CZX twitching motility protein EA714_014245 ENOG4105CZX twitching motility protein EA714_014250 ENOG41090R7 Ferric uptake EA714_014280 ENOG4105E7A Glutamine amidotransferase EA714_014295 ENOG4107QKV phosphomannomutase EA714_014305 ENOG4105C4R Atp-dependent dna helicase EA714_014310 ENOG4108ZG0 Ompa motb domain protein EA714_014315 ENOG4106HNH Acyl-transferase EA714_014330 ENOG4107QMS site-determining protein EA714_014355 ENOG4105CNU cell division protein FtsK EA714_014360 ENOG4105C3M thioredoxin reductase EA714_014365 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) EA714_014375 ENOG4105KEG ribosomal-protein-alanine acetyltransferase EA714_014420 ENOG4108YXA Membrane EA714_014425 ENOG4105EUB pirin domain protein EA714_014435 ENOG4105C4K Nad synthetase EA714_014450 ENOG4105E3J oxidoreductase EA714_014455 ENOG4105C26 Dehydrogenase EA714_014460 ENOG4105DVW rieske (2Fe-2S) EA714_014470 ENOG4105C94 Transporter EA714_014475 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) EA714_014480 ENOG4105EJC lysr family transcriptional regulator EA714_014500 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding EA714_014520 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase EA714_014525 ENOG4105C34 Pseudouridine synthase EA714_014530 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane EA714_014535 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) EA714_014550 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) EA714_014580 ENOG4105C5T Phosphoribosyl pyrophosphate synthase EA714_014610 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) EA714_014620 ENOG4105DWF phosphomethylpyrimidine kinase EA714_014625 ENOG4109066 lysm domain bon superfamily protein EA714_014635 ENOG4105CHR reductase EA714_014640 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase EA714_014650 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein EA714_014655 ENOG4108BPE -transporting atpase EA714_014660 ENOG4107RTD sua5 ycio yrdc ywlc family protein EA714_014665 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) EA714_014670 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) EA714_014675 ENOG4105FE9 pseudouridine synthase EA714_014685 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) EA714_014690 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) EA714_014700 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) EA714_014705 ENOG4108K4C ec 3.1.3.12 EA714_014710 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase EA714_014715 ENOG4106UW1 Major Facilitator superfamily EA714_014735 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) EA714_014745 ENOG4105HF0 Membrane EA714_014760 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY EA714_014770 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) EA714_014830 ENOG4105D1F ATP-binding protein EA714_014840 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) EA714_014870 ENOG4105K6H D-cysteine desulfhydrase EA714_014875 ENOG4105CBX hi0933 family EA714_014900 ENOG4105DP0 ferredoxin-NADP reductase EA714_014905 ENOG4105DUM transcriptional regulator, lysR family EA714_014925 ENOG4105C8S subunit m EA714_014930 ENOG4105D65 subunit l EA714_014940 ENOG4107UFS subunit j EA714_014955 ENOG4108IEH NADH dehydrogenase subunit g EA714_014960 ENOG4107QIZ NADH dehydrogenase EA714_014965 ENOG4105GKE subunit e EA714_014985 ENOG4105BZU Histidine kinase EA714_014995 ENOG4105E0F Histidine kinase EA714_015000 ENOG4107EXC regulatoR EA714_015010 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) EA714_015020 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) EA714_015030 ENOG4105EB3 Histidine kinase EA714_015100 ENOG4105DZG Dehydrogenase EA714_015120 ENOG4105JAB phenazine biosynthesis protein, phzf family EA714_015150 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) EA714_015155 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) EA714_015165 ENOG4105ETT transcriptional Regulator, LysR family EA714_015185 ENOG4105CH2 amidohydrolase EA714_015195 ENOG4106P55 Transcriptional regulator EA714_015215 ENOG4106P55 Transcriptional regulator EA714_015220 ENOG4107EFR Flavocytochrome c EA714_015230 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F EA714_015235 ENOG4107RGD Major Facilitator superfamily EA714_015240 ENOG4105C1G acyl-Coa dehydrogenase EA714_015245 ENOG4105ETT transcriptional Regulator, LysR family EA714_015280 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) EA714_015285 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) EA714_015290 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) EA714_015305 ENOG4105VR0 copper resistance EA714_015310 ENOG4105E3B Multicopper oxidase EA714_015320 ENOG4108HCJ Hydrolase EA714_015325 ENOG4105DJV ribulose-phosphate 3-epimerase EA714_015350 ENOG41072GX Peptidase M22 Glycoprotease EA714_015355 ENOG4108Z0R Transferase EA714_015400 ENOG4105CRQ synthase (Component I) EA714_015410 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) EA714_015415 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) EA714_015420 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) EA714_015490 ENOG4105K56 Transcriptional regulator EA714_015495 ENOG4108ZHJ Organic hydroperoxide resistance protein EA714_015500 ENOG4107QHF type ii secretion system protein e EA714_015520 ENOG4105C2M dna polymerase I EA714_015525 ENOG4108VIA integral membrane protein EA714_015530 ENOG4105II7 pyrroline-5-carboxylate reductase EA714_015535 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) EA714_015545 ENOG4105C9X ppx gppa phosphatase EA714_015555 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) EA714_015575 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) EA714_015600 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) EA714_015615 ENOG4105W39 Membrane EA714_015620 ENOG4105CYM Glutathione S-transferase EA714_015640 ENOG4105CEY Amp-dependent synthetase and ligase EA714_015645 ENOG4105N42 UPF0307 protein EA714_015650 ENOG41080Z8 PHOSPHOCARRIER protein EA714_015670 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase EA714_015675 ENOG4105DJ0 Poly(A) Polymerase EA714_015680 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein EA714_015685 ENOG4105DXN mazG family EA714_015695 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) EA714_015710 ENOG4105C6T cysteine synthase EA714_015715 ENOG4105BZU Histidine kinase EA714_015720 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase EA714_015725 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase EA714_015730 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) EA714_015745 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) EA714_015750 ENOG4105W8H transhydrogenase (subunit alpha EA714_015755 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) EA714_015760 ENOG4106UX7 integral membrane protein EA714_015775 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) EA714_015785 ENOG4107RSM transcriptional regulator EA714_015795 ENOG4105CUZ uba thif-type nad fad binding protein EA714_015805 ENOG4107QM5 aconitate hydratase EA714_015810 ENOG4105F8V Hydrolase, tatD family EA714_015825 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) EA714_015850 ENOG4105BZU Histidine kinase EA714_015860 ENOG4108ZP8 Acetolactate synthase small subunit EA714_015865 ENOG4105C7K acetolactate synthase EA714_015890 ENOG4105DJY efflux transporter, rnd family, mfp subunit EA714_015895 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) EA714_015900 ENOG4105ENJ RND efflux system, outer membrane lipoprotein EA714_015905 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH EA714_015915 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) EA714_015920 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) EA714_015930 ENOG4105VW4 glutaredoxin 3 EA714_015950 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) EA714_015955 ENOG4105C2D reductase EA714_015965 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) EA714_015995 ENOG4105C84 Histidine ammonia-lyase EA714_016010 ENOG4105CEY Amp-dependent synthetase and ligase EA714_016025 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) EA714_016045 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) EA714_016065 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) EA714_016085 ENOG4105WVQ Fe-S assembly protein IscX EA714_016100 ENOG4105CN1 protease EA714_016115 ENOG4106HB6 Alpha beta hydrolase EA714_016125 ENOG4105C26 Dehydrogenase EA714_016130 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family EA714_016135 ENOG4105C6Z Gluconate EA714_016140 ENOG4108UHU Aldolase EA714_016145 ENOG4105C01 Dihydroxy-acid dehydratase EA714_016150 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) EA714_016155 ENOG4108DNC Involved in acetate metabolism (By similarity) EA714_016160 ENOG4107GFK fumarate EA714_016180 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) EA714_016190 ENOG4108ESX Receptor EA714_016200 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) EA714_016210 ENOG4105DWV Homoserine O-trans-acetylase EA714_016310 ENOG4105CIY formyltetrahydrofolate deformylase EA714_016320 ENOG4107RGH Aldehyde dehydrogenase EA714_016325 ENOG4105KDC 50s ribosomal protein l28 EA714_016330 ENOG4105W0E 50S ribosomal protein L33 EA714_016335 ENOG4105CKD glutathione-regulated potassium-efflux system protein EA714_016355 ENOG4105VFU Rna-binding protein EA714_016360 ENOG4105C4R Atp-dependent dna helicase EA714_016375 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) EA714_016385 ENOG4105KVH Transcriptional regulator EA714_016395 ENOG41069P5 Protein slyX homolog EA714_016400 ENOG4105C5H ABC transporter EA714_016405 ENOG4105N14 lysine exporter protein LysE YggA EA714_016410 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase EA714_016420 ENOG4105CK2 sodium dicarboxylate symporter EA714_016475 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) EA714_016500 ENOG4105DUM transcriptional regulator, lysR family EA714_016525 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase EA714_016540 ENOG4108W5M transcriptional regulator EA714_016555 ENOG4105D29 Helix-turn-helix type 11 domain protein EA714_016560 ENOG4107XGZ Hydrolase EA714_016565 ENOG4105EI2 Pseudouridine synthase EA714_016575 ENOG4105C03 ribonuclease EA714_016595 ENOG4105CBN LysR family transcriptional regulator EA714_016600 ENOG4105EMU Dehydrogenase EA714_016605 ENOG4105CSA Coproporphyrinogen iii oxidase EA714_016615 ENOG4107QI1 Mate efflux family protein EA714_016625 ENOG4107T8P acyl-Coa dehydrogenase EA714_016670 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) EA714_016675 ENOG4105C5X domain protein EA714_016690 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) EA714_016700 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase EA714_016705 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) EA714_016710 ENOG4108JU5 Magnesium and cobalt efflux protein EA714_016715 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) EA714_016720 ENOG4108Z7R Chaperone CsaA EA714_016730 ENOG4108VAU general secretion pathway protein G EA714_016735 ENOG4105D7Q type ii secretion system EA714_016740 ENOG4105C25 Primosomal protein n' EA714_016745 ENOG4105CKD glutathione-regulated potassium-efflux system protein EA714_016750 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) EA714_016760 ENOG4105DVC DnaJ domain protein EA714_016765 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) EA714_016770 ENOG4107QUT magnesium and cobalt transport protein CorA EA714_016790 ENOG4107QYX exodeoxyribonuclease v alpha EA714_016795 ENOG4107QKA exodeoxyribonuclease V beta EA714_016800 ENOG4105DSY exodeoxyribonuclease V, gamma EA714_016810 ENOG4105CSR polyphosphate kinase 2 EA714_016820 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) EA714_016835 ENOG41061H0 Monooxygenase EA714_016840 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase EA714_016855 ENOG4105D65 subunit l EA714_016860 ENOG4108ZE9 Monovalent cation H antiporter subunit C EA714_016865 ENOG4107R4Z monovalent cation h antiporter subunit d EA714_016870 ENOG4105SC1 monovalent cation H antiporter subunit E EA714_016875 ENOG4105W4C monovalent cation H antiporter subunit F EA714_016880 ENOG4105KJM monovalent cation h antiporter subunit g EA714_016895 ENOG4105CHV Transcription elongation factor NusA EA714_016920 ENOG4107EJC Preprotein translocase subunit SecG EA714_016930 ENOG4107QHF type ii secretion system protein e EA714_016945 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) EA714_016955 ENOG4105C2N RNA methyltransferase TrmH family group 3 EA714_016970 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) EA714_016980 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) EA714_017010 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) EA714_017015 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase EA714_017085 ENOG4107ZXU DSBA oxidoreductase EA714_017100 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) EA714_017115 ENOG4105D3Y Na H antiporter EA714_017120 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) EA714_017170 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) EA714_017175 ENOG4105PM1 preprotein translocase subunit SecE EA714_017215 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) EA714_017220 ENOG4105TV9 FHA Domain-Containing protein EA714_017225 ENOG4105GVR general secretion pathway protein D EA714_017240 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS EA714_017265 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) EA714_017270 ENOG4108NEV two component transcriptional regulator, LytTR family EA714_017275 ENOG4108HRK Histidine kinase EA714_017290 ENOG4108UTW Plays a role in the regulation of phosphate uptake EA714_017295 ENOG4105DFG type I secretion outer membrane protein EA714_017300 ENOG4108RNG Permease of the drug metabolite transporter EA714_017325 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) EA714_017330 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters EA714_017335 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) EA714_017340 ENOG4105CNI cell division protein FtsW EA714_017355 ENOG4105CE1 Ferrous iron transport protein b EA714_017365 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EA714_017370 ENOG4105T95 Thiol disulfide interChange protein EA714_017375 ENOG4105D6E homoserine dehydrogenase EA714_017385 ENOG41061WM D-Alanyl-D-Alanine EA714_017395 ENOG4107TUY Histidine kinase EA714_017400 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EA714_017405 ENOG4105CN1 protease EA714_017410 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) EA714_017415 ENOG4108K5H permease YjgP YjgQ family protein EA714_017455 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) EA714_017465 ENOG4105BZU Histidine kinase EA714_017480 ENOG4105C0P Mg chelatase subunit ChlI EA714_017490 ENOG4108R0M Aminoglycoside EA714_017535 ENOG4105CHH sulfate transporter EA714_017590 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) EA714_017640 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EA714_017670 ENOG4105CHH sulfate transporter EA714_017705 ENOG4105C0P Mg chelatase subunit ChlI EA714_017710 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EA714_017720 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EA714_017730 ENOG4105EPF Outer membrane porin EA714_017735 ENOG4105F0N pyrophosphate phospho-hydrolase EA714_017750 ENOG4105CEY Amp-dependent synthetase and ligase EA714_017755 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EA714_017760 ENOG41079KZ Major Facilitator Superfamily EA714_017765 ENOG4105EN6 Membrane EA714_017775 ENOG4105EE5 Membrane protein terC EA714_017780 ENOG4108URH decarboxylase EA714_017795 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) EA714_017810 ENOG4105CCT upf0313 protein EA714_017830 ENOG4105CS1 NAD(P)H quinone oxidoreductase EA714_017840 ENOG4105C6T cysteine synthase EA714_017875 ENOG4105Y7M Transcriptional regulator, TetR family EA714_017910 ENOG4105C79 DNA protecting protein DprA EA714_017925 ENOG4108IND Tetr family transcriptional regulator EA714_017930 ENOG4107RTG Major Facilitator superfamily EA714_017940 ENOG4108V06 Glutathione peroxidase EA714_017980 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) EA714_018005 ENOG4105FDK ABC transporter EA714_018010 ENOG4105FAV ABC, transporter EA714_018020 ENOG4105EZR dyp-type peroxidase family protein EA714_018030 ENOG4107R1I NAD-dependent malic enzyme EA714_018055 ENOG4105EUB pirin domain protein EA714_018075 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) EA714_018080 ENOG4106MP8 UPF0754 membrane protein EA714_018085 ENOG4108VBZ doxx family EA714_018090 ENOG4105DQR SNARE associated Golgi EA714_018105 ENOG4107QJE Chromosome Partitioning Protein EA714_018115 ENOG4107PSF BolA-like protein EA714_018135 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) EA714_018160 ENOG4105C1G acyl-Coa dehydrogenase EA714_018185 ENOG4105CSH Transporter EA714_018190 ENOG4105E39 Enoyl-CoA hydratase EA714_018195 ENOG4105E39 Enoyl-CoA hydratase EA714_018200 ENOG4105C1G acyl-Coa dehydrogenase EA714_018210 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase EA714_018215 ENOG4105C26 Dehydrogenase EA714_018225 ENOG4105C85 amino acid EA714_018230 ENOG4105C85 amino acid EA714_018235 ENOG4105M4H endoribonuclease L-psp EA714_018250 ENOG4105EW9 transcriptional regulator AsnC family EA714_018275 ENOG4105D3G Pseudouridine synthase EA714_018290 ENOG4108IG5 Transcriptional regulator EA714_018340 ENOG4108I0Z Aconitate hydratase EA714_018345 ENOG4105BZN citrate synthase EA714_018350 ENOG4105CR4 methylisocitrate lyase EA714_018355 ENOG4105DRR Transcriptional regulator, GntR family EA714_018365 ENOG4105CGF Aromatic amino acid aminotransferase EA714_018370 ENOG4105CXG d-lactate dehydrogenase EA714_018380 ENOG41073TP transcriptional regulator EA714_018385 ENOG4105DAA L-lactate EA714_018390 ENOG4107QKV phosphomannomutase EA714_018395 ENOG4105CMR udp-glucose 4-epimerase EA714_018405 ENOG4105C6Y Udp-glucose 6-dehydrogenase EA714_018410 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase EA714_018420 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase EA714_018425 ENOG4107WZ3 Transferase EA714_018430 ENOG4105D3Q Sugar transferase EA714_018440 ENOG4105C6Y Udp-glucose 6-dehydrogenase EA714_018455 ENOG4105K64 Glycosyl transferase, family 2 EA714_018460 ENOG4108ZPC Polysaccharide pyruvyl transferase EA714_018470 ENOG4107QQG Dehydrogenase EA714_018475 ENOG4105DAY polysaccharide export protein EA714_018485 ENOG4105D75 Capsular exopolysaccharide family EA714_018490 ENOG4108V1T peptidylprolyl cis-trans isomerase EA714_018495 ENOG4108V1T peptidylprolyl cis-trans isomerase EA714_018500 ENOG4105CJR Integral membrane protein (MviN EA714_018505 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase EA714_018510 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase EA714_018520 ENOG4105HSS phospholipase C EA714_018545 ENOG41062JF Transcriptional regulator EA714_018560 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) EA714_018565 ENOG4105UBK short-chain dehydrogenase reductase EA714_018580 ENOG4107QZM n-acetylglutamate synthase EA714_018585 ENOG4105GVF (ABC) transporter EA714_018590 ENOG4105GVF (ABC) transporter EA714_018595 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) EA714_018600 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component EA714_018605 ENOG4108VM9 ABC, transporter EA714_018610 ENOG4108R86 Transcriptional regulator EA714_018615 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) EA714_018625 ENOG4105DTN riboflavin biosynthesis protein ribF EA714_018630 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) EA714_018640 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase EA714_018680 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) EA714_018735 ENOG4105CVE Lytic murein transglycosylase EA714_018740 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit EA714_018745 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) EA714_018760 ENOG4105DFU Cell wall formation (By similarity) EA714_018770 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase EA714_018775 ENOG4105DU1 integral membrane protein, terc EA714_018785 ENOG4106032 Glutathionylspermidine synthase EA714_018795 ENOG4107QUY Guanine deaminase EA714_018800 ENOG4108UGV hypoxanthine phosphoribosyltransferase EA714_018810 ENOG4105T95 Thiol disulfide interChange protein EA714_018815 ENOG4105PGM cation diffusion facilitator family transporter EA714_018830 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins EA714_018845 ENOG4105VG0 50S ribosomal protein l34