locus-tag	class	description
EA714_000010	COG0592	DNA-directed DNA polymerase activity
EA714_000020	COG0187	DNA topoisomerase II activity
EA714_000030	COG0586	Pfam SNARE associated Golgi protein
EA714_000035	COG0488	(ABC) transporter
EA714_000060	COG0596	Alpha beta hydrolase
EA714_000065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EA714_000070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EA714_000115	COG0733	neurotransmitter:sodium symporter activity
EA714_000155	COG2233	PERMEase
EA714_000170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA714_000205	COG2814	Major facilitator Superfamily
EA714_000210	COG0656	L-ascorbic acid biosynthetic process
EA714_000215	COG0583	DNA-binding transcription factor activity
EA714_000230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EA714_000235	COG1064	alcohol dehydrogenase
EA714_000240	COG2818	Glycosylase
EA714_000255	COG1194	a g-specific adenine glycosylase
EA714_000275	COG2983	Belongs to the UPF0260 family
EA714_000280	COG2133	pyrroloquinoline quinone binding
EA714_000285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EA714_000290	COG2116	formate transmembrane transporter activity
EA714_000310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EA714_000315	COG1335	isochorismatase
EA714_000320	COG0385	Bile acid
EA714_000325	COG0534	Mate efflux family protein
EA714_000330	COG1683	Conserved Protein
EA714_000350	COG0625	glutathione transferase activity
EA714_000360	COG1113	amino acid transport
EA714_000370	COG0523	cobalamin synthesis protein
EA714_000380	COG2188	Transcriptional regulator
EA714_000410	COG0010	Belongs to the arginase family
EA714_000430	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EA714_000435	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EA714_000445	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EA714_000450	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EA714_000555	COG0534	Mate efflux family protein
EA714_000560	COG0436	Aminotransferase
EA714_000565	COG2733	membrane
EA714_000580	COG2918	glutathione biosynthetic process
EA714_000590	COG3501	Rhs element vgr protein
EA714_000595	COG1388	LysM domain
EA714_000595	COG0791	NLP P60 protein
EA714_000615	COG3150	esterase
EA714_000625	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_000630	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
EA714_000640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EA714_000650	COG2233	PERMEase
EA714_000655	COG2351	hydroxyisourate hydrolase activity
EA714_000690	COG3706	GGDEF domain
EA714_000705	COG1393	Belongs to the ArsC family
EA714_000710	COG0708	Exodeoxyribonuclease III
EA714_000730	COG0189	ligase activity
EA714_000750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EA714_000760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EA714_000775	COG4942	peptidase
EA714_000785	COG0508	dehydrogenase complex catalyzes the overall conversion of
EA714_000795	COG2119	membrane
EA714_000800	COG4774	siderophore transport
EA714_000805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EA714_000805	COG0426	domain, Protein
EA714_000830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EA714_000850	COG1902	pentaerythritol trinitrate reductase activity
EA714_000855	COG1519	Transferase
EA714_000860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EA714_000865	COG0668	transmembrane transport
EA714_000875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EA714_000880	COG1335	isochorismatase
EA714_000885	COG1522	sequence-specific DNA binding
EA714_000890	COG3328	transposase activity
EA714_000915	COG0784	Response regulator, receiver
EA714_000915	COG2198	Histidine kinase
EA714_000915	COG2205	protein histidine kinase activity
EA714_000920	COG3162	membrane
EA714_000925	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EA714_000935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EA714_000945	COG3706	GGDEF domain
EA714_000955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EA714_000960	COG1309	transcriptional regulator
EA714_000980	COG0352	thiamine-phosphate diphosphorylase activity
EA714_000980	COG0351	phosphomethylpyrimidine kinase
EA714_000980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EA714_000990	COG2814	Major facilitator Superfamily
EA714_001005	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EA714_001015	COG1113	amino acid transport
EA714_001025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EA714_001030	COG1012	belongs to the aldehyde dehydrogenase family
EA714_001040	COG1335	isochorismatase
EA714_001070	COG2814	Major facilitator Superfamily
EA714_001075	COG0583	DNA-binding transcription factor activity
EA714_001095	COG0667	Aldo Keto reductase
EA714_001130	COG1733	regulation of RNA biosynthetic process
EA714_001140	COG2249	NAD(P)H dehydrogenase (quinone) activity
EA714_001205	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EA714_001220	COG2329	Antibiotic biosynthesis monooxygenase
EA714_001250	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EA714_001280	COG0427	acetyl-CoA hydrolase
EA714_001295	COG0745	RESPONSE REGULATOR receiver
EA714_001305	COG0659	secondary active sulfate transmembrane transporter activity
EA714_001310	COG4221	oxidoreductase activity
EA714_001320	COG0488	(ABC) transporter
EA714_001405	COG0833	amino acid
EA714_001450	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EA714_001455	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EA714_001470	COG2226	methyltransferase
EA714_001520	COG0070	glutamate synthase
EA714_001520	COG0069	glutamate synthase activity
EA714_001520	COG0067	glutamate synthase
EA714_001525	COG0493	'glutamate synthase
EA714_001535	COG1704	LemA family
EA714_001540	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EA714_001555	COG3307	-O-antigen
EA714_001575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EA714_001590	COG0194	GDP metabolic process
EA714_001640	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EA714_001660	COG5380	lipid catabolic process
EA714_001665	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EA714_001690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EA714_001695	COG0277	FAD linked oxidase domain protein
EA714_001705	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EA714_001710	COG2249	NAD(P)H dehydrogenase (quinone) activity
EA714_001725	COG1289	transmembrane transporter activity
EA714_001735	COG0628	permease
EA714_001740	COG1192	Involved in chromosome partitioning
EA714_001770	COG0833	amino acid
EA714_001775	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EA714_001780	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EA714_001790	COG1012	belongs to the aldehyde dehydrogenase family
EA714_001830	COG0583	DNA-binding transcription factor activity
EA714_001875	COG0517	IMP dehydrogenase activity
EA714_001880	COG1983	PspC domain protein
EA714_001890	COG1960	acyl-CoA dehydrogenase activity
EA714_001905	COG0408	coproporphyrinogen oxidase activity
EA714_001925	COG0513	Belongs to the DEAD box helicase family
EA714_001935	COG1127	ABC transporter
EA714_001940	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EA714_001950	COG2854	intermembrane phospholipid transfer
EA714_001960	COG0598	Magnesium transport protein CorA
EA714_001970	COG0494	nUDIX hydrolase
EA714_001975	COG1040	competence protein
EA714_001980	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EA714_002000	COG1946	Acyl-CoA thioesterase
EA714_002005	COG1301	dicarboxylic acid transport
EA714_002020	COG1959	2 iron, 2 sulfur cluster binding
EA714_002025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EA714_002025	COG1017	nitric oxide dioxygenase activity
EA714_002030	COG0433	COG0433 Predicted ATPase
EA714_002035	COG0626	cystathionine gamma-synthase activity
EA714_002155	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EA714_002165	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EA714_002190	COG1960	acyl-CoA dehydrogenase activity
EA714_002195	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EA714_002225	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EA714_002230	COG0339	signal peptide processing
EA714_002235	COG0557	exoribonuclease II activity
EA714_002280	COG0179	Fumarylacetoacetate (FAA) hydrolase
EA714_002285	COG2169	Transcriptional regulator
EA714_002290	COG0697	spore germination
EA714_002295	COG1295	ribonuclease BN
EA714_002330	COG1702	phosphate starvation-inducible protein PhoH
EA714_002340	COG1196	nuclear chromosome segregation
EA714_002340	COG0739	heme binding
EA714_002340	COG0741	lytic transglycosylase activity
EA714_002370	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EA714_002375	COG1183	phosphatidylcholine synthase activity
EA714_002420	COG1960	acyl-CoA dehydrogenase activity
EA714_002425	COG1309	transcriptional regulator
EA714_002440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EA714_002445	COG1960	acyl-CoA dehydrogenase activity
EA714_002465	COG2969	positive regulation of protein catabolic process
EA714_002475	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EA714_002490	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EA714_002495	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EA714_002515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EA714_002525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EA714_002530	COG1408	metallophosphoesterase
EA714_002540	COG2199	diguanylate cyclase activity
EA714_002585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EA714_002585	COG3453	Protein conserved in bacteria
EA714_002600	COG1607	acyl-coa hydrolase
EA714_002630	COG2350	Protein conserved in bacteria
EA714_002640	COG0613	PHP domain protein
EA714_002645	COG3781	membrane
EA714_002655	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EA714_002660	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EA714_002670	COG1862	Preprotein translocase
EA714_002720	COG2205	protein histidine kinase activity
EA714_002725	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EA714_002745	COG0726	polysaccharide deacetylase
EA714_002750	COG0463	Glycosyl transferase, family 2
EA714_002755	COG0438	transferase activity, transferring glycosyl groups
EA714_002820	COG0625	glutathione transferase activity
EA714_002825	COG0583	DNA-binding transcription factor activity
EA714_002830	COG1960	acyl-CoA dehydrogenase activity
EA714_002835	COG1960	acyl-CoA dehydrogenase activity
EA714_002845	COG2205	protein histidine kinase activity
EA714_002850	COG0745	RESPONSE REGULATOR receiver
EA714_002855	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EA714_002875	COG2096	Adenosyltransferase
EA714_002890	COG0133	tryptophan synthase activity
EA714_002925	COG0285	dihydrofolate synthase activity
EA714_002945	COG0450	alkyl hydroperoxide reductase
EA714_002960	COG0477	Major facilitator Superfamily
EA714_002965	COG1272	protein, Hemolysin III
EA714_002995	COG0183	Belongs to the thiolase family
EA714_003000	COG2207	Transcriptional regulator
EA714_003020	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EA714_003040	COG0183	Belongs to the thiolase family
EA714_003050	COG2885	chlorophyll binding
EA714_003050	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EA714_003060	COG1690	Belongs to the RtcB family
EA714_003065	COG0833	amino acid
EA714_003075	COG2233	PERMEase
EA714_003105	COG2094	Belongs to the DNA glycosylase MPG family
EA714_003110	COG4772	TonB-dependent receptor
EA714_003115	COG1902	pentaerythritol trinitrate reductase activity
EA714_003130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EA714_003135	COG0354	folic acid binding
EA714_003145	COG3189	MarR family transcriptional regulator
EA714_003150	COG2824	Alkylphosphonate utilization operon protein PhnA
EA714_003155	COG3422	double-strand break repair
EA714_003195	COG0840	transmembrane signaling receptor activity
EA714_003215	COG5510	response to toxic substance
EA714_003225	COG2832	Protein of unknown function (DUF454)
EA714_003230	COG1376	ErfK ybiS ycfS ynhG family protein
EA714_003280	COG1289	transmembrane transporter activity
EA714_003285	COG2814	Major facilitator Superfamily
EA714_003305	COG1115	amino acid carrier protein
EA714_003310	COG1752	Esterase of the alpha-beta hydrolase superfamily
EA714_003315	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EA714_003320	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EA714_003350	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EA714_003360	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EA714_003365	COG1077	Cell shape determining protein MreB Mrl
EA714_003370	COG1792	Involved in formation and maintenance of cell shape
EA714_003375	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EA714_003380	COG0424	maF-like protein
EA714_003385	COG1530	ribonuclease E activity
EA714_003395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EA714_003415	COG2249	NAD(P)H dehydrogenase (quinone) activity
EA714_003440	COG2207	Transcriptional regulator
EA714_003460	COG1113	amino acid transport
EA714_003465	COG2828	Protein conserved in bacteria
EA714_003470	COG0142	geranyltranstransferase activity
EA714_003475	COG2315	Protein conserved in bacteria
EA714_003490	COG1752	Esterase of the alpha-beta hydrolase superfamily
EA714_003515	COG2194	sulfuric ester hydrolase activity
EA714_003520	COG0745	RESPONSE REGULATOR receiver
EA714_003525	COG0642	Histidine kinase
EA714_003535	COG0004	ammonium transporteR
EA714_003545	COG0583	DNA-binding transcription factor activity
EA714_003565	COG0525	valine-tRNA ligase activity
EA714_003575	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_003585	COG0393	Putative heavy-metal-binding
EA714_003590	COG0393	Putative heavy-metal-binding
EA714_003595	COG1538	Outer membrane efflux protein
EA714_003605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA714_003610	COG0671	phosphoesterase, PA-phosphatase related
EA714_003640	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EA714_003655	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EA714_003655	COG1648	precorrin-2 dehydrogenase activity
EA714_003660	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EA714_003665	COG1733	regulation of RNA biosynthetic process
EA714_003675	COG0531	amino acid
EA714_003690	COG0321	lipoyl(octanoyl) transferase activity
EA714_003695	COG2921	Belongs to the UPF0250 family
EA714_003735	COG2009	succinate dehydrogenase
EA714_003740	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EA714_003745	COG1053	succinate dehydrogenase
EA714_003750	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EA714_003775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EA714_003795	COG2354	Protein conserved in bacteria
EA714_003800	COG2321	neutral zinc metallopeptidase
EA714_003840	COG2843	Capsule synthesis protein
EA714_003855	COG0589	response to stress
EA714_003875	COG0505	Belongs to the CarA family
EA714_003900	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EA714_003905	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EA714_003955	COG0477	Major facilitator Superfamily
EA714_003960	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EA714_003980	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EA714_004005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EA714_004010	COG0584	glycerophosphoryl diester phosphodiesterase
EA714_004030	COG0741	lytic transglycosylase activity
EA714_004055	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EA714_004070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EA714_004100	COG0778	Nitroreductase
EA714_004115	COG1929	Belongs to the glycerate kinase type-1 family
EA714_004120	COG0243	molybdopterin cofactor binding
EA714_004125	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EA714_004130	COG3339	Conserved Protein
EA714_004140	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EA714_004155	COG1113	amino acid transport
EA714_004165	COG0019	diaminopimelate decarboxylase activity
EA714_004175	COG1280	lysine exporter protein (LysE YggA)
EA714_004180	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EA714_004210	COG0463	Glycosyl transferase, family 2
EA714_004230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA714_004260	COG4591	ABC-type transport system involved in lipoprotein release permease component
EA714_004265	COG1136	(ABC) transporter
EA714_004270	COG2333	competence protein COMEC
EA714_004270	COG0658	competence protein
EA714_004280	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EA714_004280	COG0616	signal peptide processing
EA714_004285	COG0596	Alpha beta hydrolase
EA714_004290	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EA714_004300	COG0628	permease
EA714_004335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EA714_004355	COG0823	Involved in the tonB-independent uptake of proteins
EA714_004375	COG0824	Thioesterase
EA714_004380	COG1473	amidohydrolase
EA714_004400	COG0047	phosphoribosylformylglycinamidine synthase activity
EA714_004400	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EA714_004405	COG2814	Major facilitator Superfamily
EA714_004410	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EA714_004415	COG1024	Enoyl-CoA hydratase
EA714_004420	COG1056	cytidyltransferase-related domain
EA714_004420	COG1051	belongs to the nudix hydrolase family
EA714_004430	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EA714_004445	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EA714_004475	COG0583	DNA-binding transcription factor activity
EA714_004480	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EA714_004485	COG4208	sulfate ABC transporter
EA714_004490	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EA714_004500	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EA714_004505	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EA714_004510	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EA714_004530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EA714_004545	COG0681	Belongs to the peptidase S26 family
EA714_004560	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EA714_004570	COG1381	Involved in DNA repair and RecF pathway recombination
EA714_004575	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EA714_004585	COG4221	oxidoreductase activity
EA714_004635	COG0556	nucleotide-excision repair
EA714_004830	COG5410	chromosome segregation
EA714_005020	COG2070	2-Nitropropane dioxygenase
EA714_005050	COG1215	transferase activity, transferring glycosyl groups
EA714_005065	COG0415	Belongs to the DNA photolyase family
EA714_005075	COG1252	NADH dehydrogenase
EA714_005095	COG1187	pseudouridine synthase activity
EA714_005120	COG0477	Major facilitator Superfamily
EA714_005125	COG0583	DNA-binding transcription factor activity
EA714_005140	COG0612	Peptidase, M16
EA714_005165	COG0352	thiamine-phosphate diphosphorylase activity
EA714_005200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EA714_005215	COG1309	transcriptional regulator
EA714_005225	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EA714_005230	COG0076	glutamate decarboxylase activity
EA714_005240	COG1522	sequence-specific DNA binding
EA714_005245	COG3961	Belongs to the TPP enzyme family
EA714_005250	COG1113	amino acid transport
EA714_005255	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EA714_005260	COG0573	inorganic phosphate transmembrane transporter activity
EA714_005270	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EA714_005275	COG0616	signal peptide processing
EA714_005310	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EA714_005315	COG1686	Belongs to the peptidase S11 family
EA714_005340	COG0583	DNA-binding transcription factor activity
EA714_005345	COG1067	ATP-dependent peptidase activity
EA714_005390	COG1966	Carbon starvation protein
EA714_005395	COG2879	small protein
EA714_005430	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EA714_005430	COG2508	Transcriptional regulator
EA714_005450	COG1113	amino acid transport
EA714_005455	COG0583	DNA-binding transcription factor activity
EA714_005460	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EA714_005465	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EA714_005480	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EA714_005485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EA714_005485	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EA714_005520	COG2814	Major facilitator Superfamily
EA714_005525	COG4948	Mandelate Racemase Muconate Lactonizing
EA714_005535	COG1309	transcriptional regulator
EA714_005555	COG1741	Belongs to the pirin family
EA714_005565	COG2964	Protein conserved in bacteria
EA714_005580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EA714_005585	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EA714_005590	COG4605	iron ion homeostasis
EA714_005595	COG4604	ABC transporter, ATP-binding protein
EA714_005600	COG4607	ABC-type enterochelin transport system periplasmic component
EA714_005605	COG4774	siderophore transport
EA714_005615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EA714_005620	COG1021	2,3-dihydroxybenzoate-AMP ligase
EA714_005625	COG1535	isochorismatase
EA714_005625	COG3433	isochorismatase activity
EA714_005640	COG1132	(ABC) transporter
EA714_005650	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EA714_005660	COG1169	isochorismate synthase
EA714_005675	COG3739	integral membrane protein
EA714_005705	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EA714_005735	COG0308	aminopeptidase N
EA714_005740	COG0512	Glutamine amidotransferase of anthranilate synthase
EA714_005750	COG3104	oligopeptide transport
EA714_005765	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EA714_005800	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EA714_005805	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EA714_005810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EA714_005830	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EA714_005835	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EA714_005840	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EA714_005855	COG1960	acyl-CoA dehydrogenase activity
EA714_005860	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EA714_005865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EA714_005875	COG2223	nitrite transmembrane transporter activity
EA714_005885	COG0024	Methionine aminopeptidase
EA714_005890	COG0052	Belongs to the universal ribosomal protein uS2 family
EA714_005905	COG2207	Transcriptional regulator
EA714_005930	COG2951	lytic endotransglycosylase activity
EA714_005935	COG0772	Belongs to the SEDS family
EA714_005950	COG0842	Transport permease protein
EA714_005955	COG1131	(ABC) transporter
EA714_005990	COG1538	Outer membrane efflux protein
EA714_006000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA714_006025	COG4215	(ABC) transporter
EA714_006030	COG4160	amino acid transport
EA714_006035	COG4598	ABC transporter
EA714_006045	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EA714_006055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EA714_006070	COG1720	tRNA m6t6A37 methyltransferase activity
EA714_006090	COG0745	RESPONSE REGULATOR receiver
EA714_006095	COG0642	Histidine kinase
EA714_006105	COG0494	nUDIX hydrolase
EA714_006115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EA714_006120	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EA714_006125	COG3139	Protein of unknown function (DUF1315)
EA714_006130	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EA714_006140	COG1301	dicarboxylic acid transport
EA714_006145	COG1960	acyl-CoA dehydrogenase activity
EA714_006150	COG2819	hydrolase of the alpha beta superfamily
EA714_006160	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EA714_006170	COG2195	Cleaves the N-terminal amino acid of tripeptides
EA714_006175	COG1234	tRNA 3'-trailer cleavage
EA714_006205	COG2363	Small membrane protein
EA714_006225	COG0513	Belongs to the DEAD box helicase family
EA714_006235	COG0778	Nitroreductase
EA714_006265	COG1286	toxin biosynthetic process
EA714_006290	COG4783	chaperone-mediated protein folding
EA714_006295	COG1610	YqeY-like protein
EA714_006300	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EA714_006395	COG3111	PFAM Bacterial OB fold (BOF) protein
EA714_006420	COG3243	poly(R)-hydroxyalkanoic acid synthase
EA714_006425	COG0786	glutamate:sodium symporter activity
EA714_006435	COG2186	Transcriptional regulator
EA714_006485	COG0477	Major facilitator Superfamily
EA714_006515	COG2985	domain, Protein
EA714_006525	COG2995	paraquat-inducible protein a
EA714_006530	COG3008	intermembrane lipid transfer
EA714_006530	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EA714_006540	COG1794	racemase activity, acting on amino acids and derivatives
EA714_006570	COG1301	dicarboxylic acid transport
EA714_006580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EA714_006585	COG2011	ABC-type metal ion transport system permease component
EA714_006590	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EA714_006595	COG1464	Belongs to the NlpA lipoprotein family
EA714_006600	COG0151	Belongs to the GarS family
EA714_006605	COG0138	bifunctional purine biosynthesis protein purh
EA714_006610	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EA714_006640	COG2308	Evidence 4 Homologs of previously reported genes of
EA714_006650	COG1305	Transglutaminase-like
EA714_006660	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EA714_006665	COG0305	Participates in initiation and elongation during chromosome replication
EA714_006690	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EA714_006700	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EA714_006705	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EA714_006730	COG0726	polysaccharide deacetylase
EA714_006730	COG1649	PFAM Uncharacterised BCR, COG1649
EA714_006735	COG1215	transferase activity, transferring glycosyl groups
EA714_006740	COG3658	cytochrome
EA714_006750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EA714_006770	COG0583	DNA-binding transcription factor activity
EA714_006790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EA714_006795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EA714_006810	COG1960	acyl-CoA dehydrogenase activity
EA714_006815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EA714_006820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EA714_006845	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EA714_006850	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EA714_006860	COG2205	protein histidine kinase activity
EA714_006865	COG0745	RESPONSE REGULATOR receiver
EA714_006870	COG0174	glutamine synthetase
EA714_006890	COG0729	surface antigen
EA714_006920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EA714_006925	COG2814	Major facilitator Superfamily
EA714_006940	COG0583	DNA-binding transcription factor activity
EA714_006955	COG1187	pseudouridine synthase activity
EA714_006975	COG0802	atpase or kinase
EA714_006980	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EA714_006990	COG1923	regulation of RNA biosynthetic process
EA714_006995	COG0697	spore germination
EA714_007010	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EA714_007025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EA714_007025	COG0519	Catalyzes the synthesis of GMP from XMP
EA714_007030	COG4302	ethanolamine ammonia-lyase activity
EA714_007035	COG4303	Ethanolamine ammonia lyase large subunit
EA714_007040	COG0531	amino acid
EA714_007060	COG1454	alcohol dehydrogenase
EA714_007065	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EA714_007075	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EA714_007095	COG0308	aminopeptidase N
EA714_007105	COG4221	oxidoreductase activity
EA714_007115	COG1605	Chorismate mutase
EA714_007135	COG1309	transcriptional regulator
EA714_007145	COG0668	transmembrane transport
EA714_007175	COG4773	Receptor
EA714_007195	COG0488	(ABC) transporter
EA714_007200	COG0589	response to stress
EA714_007215	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EA714_007225	COG3135	benzoate transporter
EA714_007230	COG1522	sequence-specific DNA binding
EA714_007245	COG0583	DNA-binding transcription factor activity
EA714_007255	COG0183	Belongs to the thiolase family
EA714_007285	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EA714_007295	COG0824	Thioesterase
EA714_007300	COG1454	alcohol dehydrogenase
EA714_007310	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EA714_007330	COG0069	glutamate synthase activity
EA714_007500	COG5410	chromosome segregation
EA714_007710	COG2814	Major facilitator Superfamily
EA714_007725	COG0511	ligase activity, forming carbon-carbon bonds
EA714_007745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EA714_007745	COG1116	anion transmembrane transporter activity
EA714_007750	COG0745	RESPONSE REGULATOR receiver
EA714_007760	COG2146	nitrite reductase [NAD(P)H] activity
EA714_007760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EA714_007765	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EA714_007770	COG0243	molybdopterin cofactor binding
EA714_007780	COG0243	molybdopterin cofactor binding
EA714_007785	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EA714_007800	COG0315	cyclic pyranopterin monophosphate synthase activity
EA714_007800	COG0521	Mo-molybdopterin cofactor biosynthetic process
EA714_007805	COG0303	'Molybdopterin
EA714_007815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EA714_007820	COG0697	spore germination
EA714_007840	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EA714_007845	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EA714_007905	COG2204	response regulator
EA714_007910	COG3852	Histidine kinase
EA714_007935	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EA714_007940	COG0575	Belongs to the CDS family
EA714_007975	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EA714_007990	COG2137	regulation of response to DNA damage stimulus
EA714_008000	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EA714_008005	COG1011	Hydrolase
EA714_008030	COG1522	sequence-specific DNA binding
EA714_008040	COG1113	amino acid transport
EA714_008055	COG0659	secondary active sulfate transmembrane transporter activity
EA714_008070	COG3316	Transposase and inactivated derivatives
EA714_008085	COG1132	(ABC) transporter
EA714_008135	COG0482	sulfurtransferase activity
EA714_008155	COG3173	Aminoglycoside phosphotransferase
EA714_008165	COG2433	Pfam Transposase IS66
EA714_008190	COG3316	Transposase and inactivated derivatives
EA714_008210	COG3300	MHYT domain
EA714_008210	COG5001	Diguanylate cyclase
EA714_008230	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EA714_008230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EA714_008230	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EA714_008235	COG1105	Belongs to the carbohydrate kinase PfkB family
EA714_008240	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EA714_008240	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EA714_008270	COG0024	Methionine aminopeptidase
EA714_008275	COG0583	DNA-binding transcription factor activity
EA714_008285	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EA714_008290	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EA714_008295	COG0516	GMP reductase activity
EA714_008295	COG0517	IMP dehydrogenase activity
EA714_008320	COG0552	protein localization to endoplasmic reticulum
EA714_008330	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EA714_008345	COG4890	Cyd operon protein YbgT
EA714_008350	COG1294	oxidase, subunit
EA714_008365	COG1585	Membrane protein implicated in regulation of membrane protease activity
EA714_008375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EA714_008380	COG4774	siderophore transport
EA714_008395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EA714_008400	COG0569	domain protein
EA714_008405	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EA714_008435	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EA714_008440	COG0542	response to heat
EA714_008450	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EA714_008465	COG0446	pyridine nucleotide-disulphide oxidoreductase
EA714_008465	COG1902	pentaerythritol trinitrate reductase activity
EA714_008510	COG2323	membrane
EA714_008515	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EA714_008525	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EA714_008530	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EA714_008535	COG0183	Belongs to the thiolase family
EA714_008540	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EA714_008545	COG0596	Alpha beta hydrolase
EA714_008550	COG2271	Major facilitator Superfamily
EA714_008555	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EA714_008560	COG3485	protocatechuate 3,4-dioxygenase
EA714_008565	COG3485	protocatechuate 3,4-dioxygenase
EA714_008570	COG0710	3-dehydroquinate dehydratase activity
EA714_008575	COG3420	alginic acid biosynthetic process
EA714_008580	COG3659	wide pore channel activity
EA714_008585	COG4993	Dehydrogenase
EA714_008595	COG2391	methyltransferase activity
EA714_008610	COG1414	Transcriptional regulator
EA714_008615	COG0583	DNA-binding transcription factor activity
EA714_008620	COG1960	acyl-CoA dehydrogenase activity
EA714_008645	COG2814	Major facilitator Superfamily
EA714_008655	COG0154	amidase activity
EA714_008675	COG4638	Rieske (2fe-2S)
EA714_008685	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_008695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EA714_008705	COG3733	amine oxidase
EA714_008715	COG1012	belongs to the aldehyde dehydrogenase family
EA714_008725	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EA714_008730	COG0183	Belongs to the thiolase family
EA714_008735	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EA714_008740	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EA714_008750	COG4829	muconolactone delta-isomerase
EA714_008755	COG4948	Mandelate Racemase Muconate Lactonizing
EA714_008760	COG0583	DNA-binding transcription factor activity
EA714_008770	COG2186	Transcriptional regulator
EA714_008790	COG1012	belongs to the aldehyde dehydrogenase family
EA714_008810	COG1960	acyl-CoA dehydrogenase activity
EA714_008815	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_008820	COG3829	transcription factor binding
EA714_008830	COG3162	membrane
EA714_008845	COG1012	belongs to the aldehyde dehydrogenase family
EA714_008860	COG0753	catalase activity
EA714_008885	COG1846	Transcriptional regulator
EA714_008890	COG1902	pentaerythritol trinitrate reductase activity
EA714_008890	COG0446	pyridine nucleotide-disulphide oxidoreductase
EA714_008900	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EA714_008930	COG1309	transcriptional regulator
EA714_008940	COG1335	isochorismatase
EA714_008950	COG0583	DNA-binding transcription factor activity
EA714_008960	COG0475	glutathione-regulated potassium exporter activity
EA714_008960	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EA714_008970	COG1473	amidohydrolase
EA714_008985	COG2831	hemolysin activation secretion protein
EA714_008990	COG3210	domain, Protein
EA714_009035	COG0583	DNA-binding transcription factor activity
EA714_009060	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EA714_009065	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EA714_009085	COG1566	PFAM secretion protein HlyD family protein
EA714_009100	COG1012	belongs to the aldehyde dehydrogenase family
EA714_009105	COG0129	dihydroxy-acid dehydratase activity
EA714_009115	COG0583	DNA-binding transcription factor activity
EA714_009120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EA714_009130	COG2084	Dehydrogenase
EA714_009135	COG2207	Transcriptional regulator
EA714_009150	COG1064	alcohol dehydrogenase
EA714_009165	COG1120	ATPase activity
EA714_009185	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EA714_009305	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EA714_009360	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_009375	COG2207	Transcriptional regulator
EA714_009385	COG2205	protein histidine kinase activity
EA714_009390	COG0745	RESPONSE REGULATOR receiver
EA714_009395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA714_009400	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EA714_009405	COG1538	Outer membrane efflux protein
EA714_009415	COG2072	flavoprotein involved in K transport
EA714_009435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EA714_009455	COG3539	Fimbrial protein
EA714_009485	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EA714_009495	COG0753	catalase activity
EA714_009510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EA714_009575	COG1535	isochorismatase
EA714_009575	COG3433	isochorismatase activity
EA714_009580	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_009585	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EA714_009590	COG4149	molybdate abc transporter
EA714_009595	COG0725	ABC transporter, periplasmic molybdate-binding protein
EA714_009605	COG4638	Rieske (2fe-2S)
EA714_009610	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EA714_009615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EA714_009615	COG0543	2 iron, 2 sulfur cluster binding
EA714_009630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EA714_009640	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_009645	COG0412	Dienelactone hydrolase
EA714_009655	COG2207	Transcriptional regulator
EA714_009665	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_009670	COG2610	gluconate transmembrane transporter activity
EA714_009680	COG0583	DNA-binding transcription factor activity
EA714_009690	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EA714_009695	COG2031	fatty acid transporter
EA714_009700	COG0183	Belongs to the thiolase family
EA714_009705	COG0583	DNA-binding transcription factor activity
EA714_009710	COG0583	DNA-binding transcription factor activity
EA714_009725	COG1027	Aspartate ammonia-lyase
EA714_009735	COG0477	Major facilitator Superfamily
EA714_009755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EA714_009760	COG4521	taurine ABC transporter
EA714_009785	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EA714_009790	COG1733	regulation of RNA biosynthetic process
EA714_009795	COG3708	Transcriptional regulator
EA714_009795	COG2207	Transcriptional regulator
EA714_009810	COG0730	response to heat
EA714_009820	COG3453	Protein conserved in bacteria
EA714_009820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EA714_009830	COG3781	membrane
EA714_009835	COG1063	alcohol dehydrogenase
EA714_009845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EA714_009850	COG0508	dehydrogenase complex catalyzes the overall conversion of
EA714_009855	COG0022	dehydrogenase e1 component
EA714_009860	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EA714_009865	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EA714_009880	COG3706	GGDEF domain
EA714_009895	COG0133	tryptophan synthase activity
EA714_009905	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EA714_009940	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EA714_009965	COG2226	methyltransferase
EA714_010020	COG0842	Transport permease protein
EA714_010025	COG0842	Transport permease protein
EA714_010030	COG1131	(ABC) transporter
EA714_010045	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EA714_010050	COG4773	Receptor
EA714_010070	COG0730	response to heat
EA714_010075	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EA714_010095	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EA714_010155	COG4264	IucA IucC family
EA714_010160	COG4264	IucA IucC family
EA714_010180	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EA714_010195	COG1960	acyl-CoA dehydrogenase activity
EA714_010200	COG1960	acyl-CoA dehydrogenase activity
EA714_010205	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EA714_010210	COG2207	Transcriptional regulator
EA714_010215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EA714_010220	COG0776	regulation of translation
EA714_010245	COG0822	iron-sulfur transferase activity
EA714_010250	COG0316	Belongs to the HesB IscA family
EA714_010280	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EA714_010300	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EA714_010305	COG0702	epimerase
EA714_010340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EA714_010350	COG0339	signal peptide processing
EA714_010400	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EA714_010405	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EA714_010435	COG0776	regulation of translation
EA714_010455	COG0590	tRNA wobble adenosine to inosine editing
EA714_010485	COG2165	general secretion pathway protein
EA714_010500	COG0084	hydrolase, TatD family'
EA714_010520	COG1663	tetraacyldisaccharide 4'-kinase activity
EA714_010525	COG1132	(ABC) transporter
EA714_010535	COG0811	peptide transport
EA714_010540	COG1475	DNA binding
EA714_010545	COG1192	Involved in chromosome partitioning
EA714_010555	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EA714_010570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EA714_010575	COG0191	fructose-bisphosphate aldolase activity
EA714_010595	COG0424	maF-like protein
EA714_010600	COG2850	peptidyl-arginine hydroxylation
EA714_010610	COG0640	Transcriptional regulator
EA714_010620	COG3619	membrane
EA714_010625	COG3122	Protein conserved in bacteria
EA714_010630	COG1132	(ABC) transporter
EA714_010650	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EA714_010655	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EA714_010665	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EA714_010665	COG0506	proline dehydrogenase activity
EA714_010665	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EA714_010670	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EA714_010685	COG3698	Phosphodiester glycosidase
EA714_010695	COG2353	YceI-like domain
EA714_010705	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EA714_010755	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EA714_010755	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EA714_010780	COG3539	Fimbrial protein
EA714_010785	COG3121	Chaperone
EA714_010815	COG0697	spore germination
EA714_010825	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EA714_010835	COG0583	DNA-binding transcription factor activity
EA714_010855	COG1309	transcriptional regulator
EA714_010870	COG1522	sequence-specific DNA binding
EA714_010880	COG1126	abc transporter atp-binding protein
EA714_010885	COG0765	amino acid transport
EA714_010890	COG0765	amino acid transport
EA714_010920	COG1464	Belongs to the NlpA lipoprotein family
EA714_010930	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EA714_010935	COG2011	ABC-type metal ion transport system permease component
EA714_010940	COG0012	GTP binding
EA714_010965	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EA714_011005	COG0386	Belongs to the glutathione peroxidase family
EA714_011015	COG0436	Aminotransferase
EA714_011055	COG3634	alkyl hydroperoxide reductase activity
EA714_011070	COG0583	DNA-binding transcription factor activity
EA714_011075	COG0798	PFAM Bile acid sodium symporter
EA714_011080	COG0640	Transcriptional regulator
EA714_011095	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EA714_011105	COG0583	DNA-binding transcription factor activity
EA714_011115	COG1953	Uracil, thiamine, allantoin
EA714_011125	COG2175	clavaminate synthase activity
EA714_011130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EA714_011135	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EA714_011140	COG4521	taurine ABC transporter
EA714_011160	COG0477	Major facilitator Superfamily
EA714_011185	COG1271	oxidase subunit
EA714_011190	COG1294	oxidase, subunit
EA714_011200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EA714_011220	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EA714_011240	COG3052	prosthetic group binding
EA714_011245	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
EA714_011255	COG2814	Major facilitator Superfamily
EA714_011275	COG1346	cytolysis
EA714_011285	COG0583	DNA-binding transcription factor activity
EA714_011290	COG0625	glutathione transferase activity
EA714_011295	COG0625	glutathione transferase activity
EA714_011300	COG0583	DNA-binding transcription factor activity
EA714_011315	COG1045	serine acetyltransferase
EA714_011320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EA714_011325	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EA714_011335	COG1280	lysine exporter protein (LysE YggA)
EA714_011350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EA714_011355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EA714_011360	COG1126	abc transporter atp-binding protein
EA714_011365	COG0765	amino acid transport
EA714_011370	COG0765	amino acid transport
EA714_011390	COG0784	Response regulator, receiver
EA714_011390	COG2205	protein histidine kinase activity
EA714_011410	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EA714_011430	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_011475	COG0583	DNA-binding transcription factor activity
EA714_011495	COG0318	PFAM AMP-dependent synthetase and ligase
EA714_011500	COG1309	transcriptional regulator
EA714_011505	COG1960	acyl-CoA dehydrogenase activity
EA714_011510	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EA714_011515	COG1024	Enoyl-CoA hydratase
EA714_011530	COG0583	DNA-binding transcription factor activity
EA714_011545	COG1960	acyl-CoA dehydrogenase activity
EA714_011555	COG2814	Major facilitator Superfamily
EA714_011565	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EA714_011570	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EA714_011575	COG2814	Major facilitator Superfamily
EA714_011580	COG1960	acyl-CoA dehydrogenase activity
EA714_011585	COG1024	Enoyl-CoA hydratase
EA714_011590	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_011595	COG1250	3-hydroxyacyl-CoA dehydrogenase
EA714_011600	COG0183	Belongs to the thiolase family
EA714_011610	COG2814	Major facilitator Superfamily
EA714_011620	COG1024	Enoyl-CoA hydratase
EA714_011635	COG1960	acyl-CoA dehydrogenase activity
EA714_011640	COG2814	Major facilitator Superfamily
EA714_011645	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EA714_011650	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EA714_011665	COG3842	ATPase activity
EA714_011670	COG1840	ABC-type Fe3 transport system, periplasmic component
EA714_011680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EA714_011685	COG1414	Transcriptional regulator
EA714_011695	COG0583	DNA-binding transcription factor activity
EA714_011700	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EA714_011705	COG1012	belongs to the aldehyde dehydrogenase family
EA714_011715	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EA714_011725	COG1012	belongs to the aldehyde dehydrogenase family
EA714_011730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EA714_011735	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EA714_011740	COG2267	carboxylic ester hydrolase activity
EA714_011760	COG3038	cytochrome b561
EA714_011765	COG0753	catalase activity
EA714_011805	COG2050	protein possibly involved in aromatic compounds catabolism
EA714_011815	COG3327	negative regulation of DNA-templated transcription, initiation
EA714_011820	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EA714_011825	COG0183	Belongs to the thiolase family
EA714_011830	COG1250	3-hydroxyacyl-CoA dehydrogenase
EA714_011835	COG1024	Enoyl-CoA hydratase
EA714_011840	COG1024	Enoyl-CoA hydratase
EA714_011845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EA714_011850	COG2151	metal-sulfur cluster biosynthetic enzyme
EA714_011855	COG3396	Phenylacetate-CoA oxygenase
EA714_011860	COG3460	Phenylacetate-CoA oxygenase
EA714_011865	COG3396	Phenylacetate-CoA oxygenase
EA714_011870	COG2030	dehydratase
EA714_011870	COG1012	belongs to the aldehyde dehydrogenase family
EA714_011875	COG1760	l-serine dehydratase
EA714_011880	COG0531	amino acid
EA714_011885	COG1012	belongs to the aldehyde dehydrogenase family
EA714_011900	COG0446	pyridine nucleotide-disulphide oxidoreductase
EA714_011910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EA714_011930	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EA714_011945	COG0789	Transcriptional regulator
EA714_011960	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EA714_011975	COG2807	transmembrane transport
EA714_011980	COG0590	tRNA wobble adenosine to inosine editing
EA714_011990	COG0583	DNA-binding transcription factor activity
EA714_012030	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EA714_012030	COG2885	chlorophyll binding
EA714_012100	COG1116	anion transmembrane transporter activity
EA714_012105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EA714_012115	COG0864	Transcriptional regulator
EA714_012135	COG2249	NAD(P)H dehydrogenase (quinone) activity
EA714_012140	COG0439	Biotin carboxylase
EA714_012155	COG1063	alcohol dehydrogenase
EA714_012165	COG1309	transcriptional regulator
EA714_012190	COG0038	chloride channel
EA714_012195	COG4770	biotin carboxylase activity
EA714_012215	COG1914	H( )-stimulated, divalent metal cation uptake system
EA714_012220	COG0583	DNA-binding transcription factor activity
EA714_012235	COG3209	COG3209 Rhs family protein
EA714_012240	COG3501	Rhs element vgr protein
EA714_012275	COG1250	3-hydroxyacyl-CoA dehydrogenase
EA714_012295	COG2814	Major facilitator Superfamily
EA714_012310	COG1560	Kdo2-lipid A biosynthetic process
EA714_012320	COG5006	permease, DMT superfamily
EA714_012325	COG1522	sequence-specific DNA binding
EA714_012340	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EA714_012380	COG1538	Outer membrane efflux protein
EA714_012385	COG1137	ATPase activity
EA714_012390	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EA714_012400	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EA714_012405	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EA714_012405	COG0517	IMP dehydrogenase activity
EA714_012440	COG1733	regulation of RNA biosynthetic process
EA714_012445	COG2814	Major facilitator Superfamily
EA714_012485	COG1278	Cold shock
EA714_012490	COG1280	lysine exporter protein (LysE YggA)
EA714_012525	COG1570	exodeoxyribonuclease VII activity
EA714_012580	COG0583	DNA-binding transcription factor activity
EA714_012585	COG4638	Rieske (2fe-2S)
EA714_012590	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EA714_012595	COG0543	2 iron, 2 sulfur cluster binding
EA714_012595	COG0633	Ferredoxin
EA714_012600	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_012605	COG3135	benzoate transporter
EA714_012610	COG2814	Major facilitator Superfamily
EA714_012625	COG1643	Atp-dependent helicase
EA714_012630	COG0450	alkyl hydroperoxide reductase
EA714_012640	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EA714_012650	COG3634	alkyl hydroperoxide reductase activity
EA714_012670	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EA714_012675	COG0625	glutathione transferase activity
EA714_012685	COG2885	chlorophyll binding
EA714_012735	COG1765	OsmC-like protein
EA714_012745	COG0667	Aldo Keto reductase
EA714_012760	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EA714_012770	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EA714_012790	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EA714_012800	COG3038	cytochrome b561
EA714_012805	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EA714_012815	COG3316	Transposase and inactivated derivatives
EA714_012825	COG3501	Rhs element vgr protein
EA714_012845	COG4269	membrane
EA714_012860	COG0446	pyridine nucleotide-disulphide oxidoreductase
EA714_012860	COG1902	pentaerythritol trinitrate reductase activity
EA714_012870	COG5001	Diguanylate cyclase
EA714_012870	COG4251	negative regulation of phosphorylation
EA714_012870	COG3706	GGDEF domain
EA714_012870	COG2203	Gaf domain
EA714_012880	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EA714_012900	COG4172	Belongs to the ABC transporter superfamily
EA714_012905	COG4239	(ABC) transporter, permease
EA714_012910	COG4174	ABC transporter (Permease)
EA714_012920	COG0741	lytic transglycosylase activity
EA714_012920	COG1388	LysM domain
EA714_012920	COG0741	lytic transglycosylase activity
EA714_012920	COG1388	LysM domain
EA714_012925	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EA714_012965	COG0583	DNA-binding transcription factor activity
EA714_012970	COG1279	arginine transmembrane transporter activity
EA714_012990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EA714_012995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EA714_013000	COG0006	proline dipeptidase activity
EA714_013035	COG2194	sulfuric ester hydrolase activity
EA714_013080	COG0739	heme binding
EA714_013405	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EA714_013430	COG3384	dioxygenase
EA714_013440	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EA714_013445	COG2878	Part of a membrane complex involved in electron transport
EA714_013450	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EA714_013475	COG0768	penicillin binding
EA714_013480	COG0742	ribosomal rna small subunit methyltransferase
EA714_013495	COG0830	nickel cation binding
EA714_013505	COG0804	urea catabolic process
EA714_013545	COG1253	flavin adenine dinucleotide binding
EA714_013555	COG2851	Citrate transporter
EA714_013605	COG1773	rubredoxin
EA714_013610	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EA714_013620	COG0583	DNA-binding transcription factor activity
EA714_013645	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EA714_013650	COG4181	ATPase activity
EA714_013695	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EA714_013715	COG0306	phosphate transporter
EA714_013725	COG3958	Transketolase
EA714_013730	COG3959	Transketolase, thiamine diphosphate binding domain
EA714_013735	COG2271	Major facilitator Superfamily
EA714_013740	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_013745	COG0583	DNA-binding transcription factor activity
EA714_013765	COG2223	nitrite transmembrane transporter activity
EA714_013770	COG2207	Transcriptional regulator
EA714_013775	COG2066	Belongs to the glutaminase family
EA714_013780	COG0242	peptide deformylase activity
EA714_013785	COG0477	Major facilitator Superfamily
EA714_013795	COG0028	Belongs to the TPP enzyme family
EA714_013810	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_013815	COG2267	carboxylic ester hydrolase activity
EA714_013825	COG2271	Major facilitator Superfamily
EA714_013830	COG0446	pyridine nucleotide-disulphide oxidoreductase
EA714_013840	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_013860	COG1414	Transcriptional regulator
EA714_013875	COG1024	Enoyl-CoA hydratase
EA714_013885	COG1215	transferase activity, transferring glycosyl groups
EA714_013890	COG0726	polysaccharide deacetylase
EA714_013890	COG1649	PFAM Uncharacterised BCR, COG1649
EA714_013900	COG4681	YaeQ
EA714_013910	COG0523	cobalamin synthesis protein
EA714_013920	COG1607	acyl-coa hydrolase
EA714_013930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EA714_013935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EA714_013940	COG1309	transcriptional regulator
EA714_013965	COG2040	homocysteine
EA714_013970	COG0531	amino acid
EA714_014025	COG1595	DNA-templated transcription, initiation
EA714_014035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EA714_014040	COG0477	Major facilitator Superfamily
EA714_014165	COG0582	viral genome integration into host DNA
EA714_014175	COG0405	Gamma-glutamyltransferase
EA714_014180	COG2814	Major facilitator Superfamily
EA714_014190	COG2050	protein possibly involved in aromatic compounds catabolism
EA714_014205	COG1090	epimerase
EA714_014225	COG0420	3'-5' exonuclease activity
EA714_014250	COG0735	belongs to the Fur family
EA714_014255	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EA714_014280	COG0121	glutamine amidotransferase
EA714_014295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EA714_014305	COG0210	DNA helicase
EA714_014310	COG2885	chlorophyll binding
EA714_014315	COG0204	Acyl-transferase
EA714_014330	COG2894	cell division
EA714_014350	COG1280	lysine exporter protein (LysE YggA)
EA714_014355	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EA714_014355	COG1674	ftsk spoiiie
EA714_014360	COG0492	ferredoxin-NADP+ reductase activity
EA714_014365	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EA714_014375	COG0456	acetyltransferase
EA714_014435	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EA714_014435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EA714_014455	COG1012	belongs to the aldehyde dehydrogenase family
EA714_014475	COG0473	3-isopropylmalate dehydrogenase activity
EA714_014480	COG0583	DNA-binding transcription factor activity
EA714_014500	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EA714_014525	COG0564	pseudouridine synthase activity
EA714_014535	COG0358	DNA primase activity
EA714_014550	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EA714_014580	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EA714_014610	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EA714_014620	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EA714_014620	COG0352	thiamine-phosphate diphosphorylase activity
EA714_014620	COG0351	phosphomethylpyrimidine kinase
EA714_014625	COG1652	LysM domain
EA714_014650	COG1399	metal-binding, possibly nucleic acid-binding protein
EA714_014655	COG3101	peptidyl-lysine hydroxylation
EA714_014660	COG0009	L-threonylcarbamoyladenylate synthase
EA714_014665	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EA714_014670	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EA714_014685	COG4106	trans-aconitate 2-methyltransferase activity
EA714_014700	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EA714_014700	COG0596	Alpha beta hydrolase
EA714_014700	COG2226	methyltransferase
EA714_014705	COG1877	trehalose-phosphatase activity
EA714_014710	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
EA714_014715	COG2223	nitrite transmembrane transporter activity
EA714_014735	COG1196	nuclear chromosome segregation
EA714_014745	COG0730	response to heat
EA714_014760	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EA714_014770	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EA714_014830	COG0489	protein tyrosine kinase activity
EA714_014840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EA714_014840	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EA714_014870	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EA714_014875	COG2081	HI0933 family
EA714_014885	COG0668	transmembrane transport
EA714_014905	COG0583	DNA-binding transcription factor activity
EA714_014925	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EA714_014930	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EA714_014960	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EA714_014995	COG2205	protein histidine kinase activity
EA714_015000	COG0745	RESPONSE REGULATOR receiver
EA714_015020	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EA714_015030	COG2205	protein histidine kinase activity
EA714_015100	COG4993	Dehydrogenase
EA714_015120	COG0384	phenazine biosynthesis protein PhzF
EA714_015150	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EA714_015155	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EA714_015165	COG0583	DNA-binding transcription factor activity
EA714_015185	COG1473	amidohydrolase
EA714_015195	COG0583	DNA-binding transcription factor activity
EA714_015215	COG0583	DNA-binding transcription factor activity
EA714_015220	COG1053	succinate dehydrogenase
EA714_015230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EA714_015235	COG2814	Major facilitator Superfamily
EA714_015240	COG1960	acyl-CoA dehydrogenase activity
EA714_015245	COG0583	DNA-binding transcription factor activity
EA714_015250	COG1063	alcohol dehydrogenase
EA714_015280	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EA714_015285	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EA714_015290	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EA714_015305	COG3667	copper resistance
EA714_015310	COG2132	Multicopper oxidase
EA714_015320	COG0561	phosphatase activity
EA714_015325	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EA714_015350	COG1214	PFAM Peptidase M22, glycoprotease
EA714_015400	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EA714_015410	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EA714_015415	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EA714_015420	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EA714_015480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EA714_015490	COG1846	Transcriptional regulator
EA714_015495	COG1764	response to oxidative stress
EA714_015535	COG0037	tRNA processing
EA714_015545	COG0248	Ppx GppA phosphatase
EA714_015575	COG0072	phenylalanine-tRNA ligase activity
EA714_015600	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EA714_015615	COG1238	metal cluster binding
EA714_015620	COG0625	glutathione transferase activity
EA714_015640	COG0318	PFAM AMP-dependent synthetase and ligase
EA714_015645	COG3028	Belongs to the UPF0307 family
EA714_015650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EA714_015670	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EA714_015675	COG0617	tRNA 3'-terminal CCA addition
EA714_015680	COG1555	photosystem II stabilization
EA714_015685	COG3956	TIGRFAM MazG family protein
EA714_015695	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EA714_015715	COG2205	protein histidine kinase activity
EA714_015715	COG0784	Response regulator, receiver
EA714_015715	COG5002	protein histidine kinase activity
EA714_015720	COG1024	Enoyl-CoA hydratase
EA714_015725	COG2084	Dehydrogenase
EA714_015730	COG3622	Belongs to the hyi family
EA714_015745	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EA714_015750	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EA714_015755	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EA714_015760	COG0697	spore germination
EA714_015770	COG2814	Major facilitator Superfamily
EA714_015775	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EA714_015785	COG0583	DNA-binding transcription factor activity
EA714_015795	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EA714_015810	COG0084	hydrolase, TatD family'
EA714_015825	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EA714_015860	COG0440	acetolactate synthase activity
EA714_015865	COG0028	Belongs to the TPP enzyme family
EA714_015890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA714_015895	COG0577	efflux transmembrane transporter activity
EA714_015895	COG1136	(ABC) transporter
EA714_015900	COG1538	Outer membrane efflux protein
EA714_015915	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EA714_015920	COG1162	GTPase activity
EA714_015930	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EA714_015950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EA714_015955	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_015995	COG2986	histidine ammonia-lyase
EA714_016010	COG0318	PFAM AMP-dependent synthetase and ligase
EA714_016020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EA714_016025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EA714_016065	COG1426	Protein conserved in bacteria
EA714_016100	COG0793	Belongs to the peptidase S41A family
EA714_016115	COG2267	carboxylic ester hydrolase activity
EA714_016125	COG1012	belongs to the aldehyde dehydrogenase family
EA714_016130	COG3265	gluconokinase activity
EA714_016140	COG0800	Aldolase
EA714_016150	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EA714_016155	COG0857	belongs to the CobB CobQ family
EA714_016155	COG0280	phosphate acetyltransferase
EA714_016160	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EA714_016160	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EA714_016180	COG0740	serine-type endopeptidase activity
EA714_016190	COG4774	siderophore transport
EA714_016200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EA714_016210	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EA714_016210	COG2813	Specifically methylates the guanine in position
EA714_016310	COG0788	formyltetrahydrofolate deformylase activity
EA714_016325	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EA714_016330	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EA714_016335	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EA714_016335	COG4651	solute:proton antiporter activity
EA714_016355	COG0724	RNA recognition motif
EA714_016360	COG0210	DNA helicase
EA714_016385	COG1733	regulation of RNA biosynthetic process
EA714_016405	COG1280	lysine exporter protein (LysE YggA)
EA714_016410	COG1560	Kdo2-lipid A biosynthetic process
EA714_016420	COG1301	dicarboxylic acid transport
EA714_016475	COG0473	3-isopropylmalate dehydrogenase activity
EA714_016540	COG0583	DNA-binding transcription factor activity
EA714_016550	COG0625	glutathione transferase activity
EA714_016555	COG2378	regulation of single-species biofilm formation
EA714_016560	COG0546	phosphoglycolate phosphatase activity
EA714_016575	COG1530	ribonuclease E activity
EA714_016595	COG0583	DNA-binding transcription factor activity
EA714_016600	COG4221	oxidoreductase activity
EA714_016605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EA714_016615	COG0534	Mate efflux family protein
EA714_016630	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EA714_016670	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EA714_016675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EA714_016690	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EA714_016700	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EA714_016700	COG0644	oxidoreductase
EA714_016705	COG0425	Belongs to the sulfur carrier protein TusA family
EA714_016710	COG4535	Mg2 and Co2 transporter CorC
EA714_016720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EA714_016740	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EA714_016745	COG0475	glutathione-regulated potassium exporter activity
EA714_016745	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EA714_016750	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EA714_016760	COG0484	heat shock protein binding
EA714_016765	COG0789	Transcriptional regulator
EA714_016770	COG0598	Magnesium transport protein CorA
EA714_016790	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EA714_016795	COG1074	ATP-dependent DNA helicase activity
EA714_016800	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EA714_016820	COG2226	methyltransferase
EA714_016835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EA714_016840	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EA714_016855	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EA714_016855	COG2111	Na H antiporter
EA714_016860	COG1006	Multisubunit Na H antiporter MnhC subunit
EA714_016865	COG0651	ATP synthesis coupled electron transport
EA714_016875	COG2212	antiporter activity
EA714_016895	COG0195	Participates in both transcription termination and antitermination
EA714_016945	COG0237	dephospho-CoA kinase activity
EA714_016955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EA714_016970	COG0497	DNA recombination
EA714_016980	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EA714_017010	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EA714_017010	COG2169	Transcriptional regulator
EA714_017015	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EA714_017085	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EA714_017100	COG0326	Molecular chaperone. Has ATPase activity
EA714_017115	COG2056	Na+-H+ antiporter family
EA714_017120	COG0596	Alpha beta hydrolase
EA714_017215	COG0546	phosphoglycolate phosphatase activity
EA714_017220	COG1716	ATPase activity
EA714_017265	COG0181	hydroxymethylbilane synthase activity
EA714_017275	COG3275	phosphorelay sensor kinase activity
EA714_017295	COG1538	Outer membrane efflux protein
EA714_017300	COG0697	spore germination
EA714_017325	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EA714_017330	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EA714_017335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EA714_017340	COG0772	Belongs to the SEDS family
EA714_017365	COG4974	Belongs to the 'phage' integrase family
EA714_017370	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EA714_017380	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EA714_017390	COG2197	response regulator
EA714_017405	COG0793	Belongs to the peptidase S41A family
EA714_017410	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EA714_017415	COG0795	lipopolysaccharide-transporting ATPase activity
EA714_017455	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EA714_017455	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EA714_017465	COG0004	ammonium transporteR
EA714_017470	COG0347	Belongs to the P(II) protein family
EA714_017480	COG0606	chelatase, subunit chli
EA714_017535	COG0659	secondary active sulfate transmembrane transporter activity
EA714_017540	COG0589	response to stress
EA714_017590	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EA714_017640	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EA714_017670	COG0659	secondary active sulfate transmembrane transporter activity
EA714_017675	COG0589	response to stress
EA714_017705	COG0606	chelatase, subunit chli
EA714_017710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EA714_017720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EA714_017735	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EA714_017750	COG0318	PFAM AMP-dependent synthetase and ligase
EA714_017760	COG0477	Major facilitator Superfamily
EA714_017765	COG2860	membrane
EA714_017775	COG1253	flavin adenine dinucleotide binding
EA714_017795	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EA714_017830	COG0655	NAD(P)H dehydrogenase (quinone) activity
EA714_017840	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EA714_017875	COG1309	transcriptional regulator
EA714_017910	COG0758	DNA mediated transformation
EA714_017920	COG0697	spore germination
EA714_017925	COG1309	transcriptional regulator
EA714_017940	COG0386	Belongs to the glutathione peroxidase family
EA714_018005	COG1121	(ABC) transporter
EA714_018010	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EA714_018015	COG1280	lysine exporter protein (LysE YggA)
EA714_018020	COG2837	iron assimilation
EA714_018030	COG0281	malic enzyme
EA714_018075	COG0519	Catalyzes the synthesis of GMP from XMP
EA714_018075	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EA714_018080	COG4399	Belongs to the UPF0754 family
EA714_018085	COG2259	Doxx family
EA714_018090	COG0586	Pfam SNARE associated Golgi protein
EA714_018105	COG1192	Involved in chromosome partitioning
EA714_018115	COG0271	Belongs to the BolA IbaG family
EA714_018135	COG2267	carboxylic ester hydrolase activity
EA714_018155	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EA714_018155	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EA714_018155	COG3321	synthase
EA714_018155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EA714_018160	COG1960	acyl-CoA dehydrogenase activity
EA714_018170	COG2197	response regulator
EA714_018180	COG3916	Acyl-homoserine-lactone synthase
EA714_018185	COG0477	Major facilitator Superfamily
EA714_018190	COG1024	Enoyl-CoA hydratase
EA714_018195	COG1024	Enoyl-CoA hydratase
EA714_018200	COG1960	acyl-CoA dehydrogenase activity
EA714_018205	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EA714_018225	COG1113	amino acid transport
EA714_018230	COG1113	amino acid transport
EA714_018235	COG0251	oxidation-reduction process
EA714_018250	COG1522	sequence-specific DNA binding
EA714_018275	COG0564	pseudouridine synthase activity
EA714_018340	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EA714_018355	COG1802	Transcriptional regulator
EA714_018365	COG1448	Aminotransferase
EA714_018370	COG0277	FAD linked oxidase domain protein
EA714_018380	COG2186	Transcriptional regulator
EA714_018390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EA714_018395	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EA714_018410	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EA714_018420	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EA714_018430	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EA714_018435	COG0438	transferase activity, transferring glycosyl groups
EA714_018455	COG1216	Glycosyl transferase, family 2
EA714_018460	COG5039	Polysaccharide pyruvyl transferase
EA714_018470	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EA714_018475	COG1596	polysaccharide export
EA714_018500	COG0728	peptidoglycan biosynthetic process
EA714_018505	COG3023	N-Acetylmuramoyl-L-alanine amidase
EA714_018560	COG0546	phosphoglycolate phosphatase activity
EA714_018565	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_018585	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EA714_018590	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EA714_018595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EA714_018600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EA714_018605	COG1116	anion transmembrane transporter activity
EA714_018610	COG1309	transcriptional regulator
EA714_018615	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EA714_018625	COG0196	riboflavin kinase activity
EA714_018630	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EA714_018640	COG1047	Peptidyl-prolyl cis-trans
EA714_018680	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EA714_018735	COG2951	lytic endotransglycosylase activity
EA714_018740	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EA714_018760	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EA714_018770	COG0671	phosphoesterase, PA-phosphatase related
EA714_018775	COG0861	Integral membrane protein TerC family
EA714_018785	COG0754	glutathionylspermidine amidase activity
EA714_018795	COG0402	S-adenosylhomocysteine deaminase activity
EA714_018810	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EA714_018815	COG1230	cation diffusion facilitator family transporter
EA714_018830	COG0706	membrane insertase activity
EA714_018845	COG0230	Belongs to the bacterial ribosomal protein bL34 family