locus-tag	class	description
EA719_000010	COG0592	DNA-directed DNA polymerase activity
EA719_000020	COG0187	DNA topoisomerase II activity
EA719_000030	COG0586	Pfam SNARE associated Golgi protein
EA719_000035	COG0488	(ABC) transporter
EA719_000060	COG0596	Alpha beta hydrolase
EA719_000065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EA719_000070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EA719_000115	COG0733	neurotransmitter:sodium symporter activity
EA719_000155	COG2233	PERMEase
EA719_000170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA719_000205	COG2814	Major facilitator Superfamily
EA719_000210	COG0656	L-ascorbic acid biosynthetic process
EA719_000215	COG0583	DNA-binding transcription factor activity
EA719_000230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EA719_000235	COG1064	alcohol dehydrogenase
EA719_000240	COG2818	Glycosylase
EA719_000255	COG1194	a g-specific adenine glycosylase
EA719_000275	COG2983	Belongs to the UPF0260 family
EA719_000280	COG2133	pyrroloquinoline quinone binding
EA719_000285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EA719_000290	COG2116	formate transmembrane transporter activity
EA719_000310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EA719_000315	COG1335	isochorismatase
EA719_000320	COG0385	Bile acid
EA719_000325	COG0534	Mate efflux family protein
EA719_000330	COG1683	Conserved Protein
EA719_000350	COG0625	glutathione transferase activity
EA719_000360	COG1113	amino acid transport
EA719_000370	COG0523	cobalamin synthesis protein
EA719_000380	COG2188	Transcriptional regulator
EA719_000410	COG0010	Belongs to the arginase family
EA719_000425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EA719_000430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EA719_000440	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EA719_000445	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EA719_000550	COG0534	Mate efflux family protein
EA719_000555	COG0436	Aminotransferase
EA719_000560	COG2733	membrane
EA719_000575	COG2918	glutathione biosynthetic process
EA719_000585	COG3501	Rhs element vgr protein
EA719_000590	COG1388	LysM domain
EA719_000590	COG0791	NLP P60 protein
EA719_000610	COG3150	esterase
EA719_000620	COG1028	Short-chain dehydrogenase reductase Sdr
EA719_000625	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
EA719_000635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EA719_000645	COG2233	PERMEase
EA719_000650	COG2351	hydroxyisourate hydrolase activity
EA719_000685	COG3706	GGDEF domain
EA719_000700	COG1393	Belongs to the ArsC family
EA719_000705	COG0708	Exodeoxyribonuclease III
EA719_000725	COG0189	ligase activity
EA719_000745	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EA719_000755	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EA719_000770	COG4942	peptidase
EA719_000780	COG0508	dehydrogenase complex catalyzes the overall conversion of
EA719_000790	COG2119	membrane
EA719_000810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EA719_000810	COG0426	domain, Protein
EA719_000835	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EA719_000855	COG1902	pentaerythritol trinitrate reductase activity
EA719_000860	COG1519	Transferase
EA719_000865	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EA719_000870	COG0668	transmembrane transport
EA719_000880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EA719_000885	COG1335	isochorismatase
EA719_000890	COG1522	sequence-specific DNA binding
EA719_000895	COG3328	transposase activity
EA719_000920	COG2205	protein histidine kinase activity
EA719_000920	COG0784	Response regulator, receiver
EA719_000920	COG2198	Histidine kinase
EA719_000925	COG3162	membrane
EA719_000930	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EA719_000940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EA719_000950	COG3706	GGDEF domain
EA719_000960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EA719_000965	COG1309	transcriptional regulator
EA719_000985	COG0352	thiamine-phosphate diphosphorylase activity
EA719_000985	COG0351	phosphomethylpyrimidine kinase
EA719_000985	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EA719_000995	COG2814	Major facilitator Superfamily
EA719_001010	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EA719_001020	COG1113	amino acid transport
EA719_001030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EA719_001035	COG1012	belongs to the aldehyde dehydrogenase family
EA719_001045	COG1335	isochorismatase
EA719_001075	COG2814	Major facilitator Superfamily
EA719_001080	COG0583	DNA-binding transcription factor activity
EA719_001100	COG0667	Aldo Keto reductase
EA719_001135	COG1733	regulation of RNA biosynthetic process
EA719_001145	COG2249	NAD(P)H dehydrogenase (quinone) activity
EA719_001210	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EA719_001225	COG2329	Antibiotic biosynthesis monooxygenase
EA719_001255	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EA719_001285	COG0427	acetyl-CoA hydrolase
EA719_001300	COG0745	RESPONSE REGULATOR receiver
EA719_001310	COG0659	secondary active sulfate transmembrane transporter activity
EA719_001315	COG4221	oxidoreductase activity
EA719_001325	COG0488	(ABC) transporter
EA719_001410	COG0833	amino acid
EA719_001455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EA719_001460	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EA719_001475	COG2226	methyltransferase
EA719_001525	COG0070	glutamate synthase
EA719_001525	COG0069	glutamate synthase activity
EA719_001525	COG0067	glutamate synthase
EA719_001530	COG0493	'glutamate synthase
EA719_001540	COG1704	LemA family
EA719_001545	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EA719_001565	COG3307	-O-antigen
EA719_001585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EA719_001600	COG0194	GDP metabolic process
EA719_001650	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EA719_001670	COG5380	lipid catabolic process
EA719_001675	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EA719_001700	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EA719_001705	COG0277	FAD linked oxidase domain protein
EA719_001715	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EA719_001720	COG2249	NAD(P)H dehydrogenase (quinone) activity
EA719_001735	COG1289	transmembrane transporter activity
EA719_001745	COG0628	permease
EA719_001750	COG1192	Involved in chromosome partitioning
EA719_001780	COG0833	amino acid
EA719_001790	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EA719_001800	COG1012	belongs to the aldehyde dehydrogenase family
EA719_001840	COG0583	DNA-binding transcription factor activity
EA719_001885	COG0517	IMP dehydrogenase activity
EA719_001890	COG1983	PspC domain protein
EA719_001900	COG1960	acyl-CoA dehydrogenase activity
EA719_001915	COG0408	coproporphyrinogen oxidase activity
EA719_001935	COG0513	Belongs to the DEAD box helicase family
EA719_001945	COG1127	ABC transporter
EA719_001950	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EA719_001960	COG2854	intermembrane phospholipid transfer
EA719_001970	COG0598	Magnesium transport protein CorA
EA719_001980	COG0494	nUDIX hydrolase
EA719_001985	COG1040	competence protein
EA719_001990	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EA719_002010	COG1946	Acyl-CoA thioesterase
EA719_002015	COG1301	dicarboxylic acid transport
EA719_002030	COG1959	2 iron, 2 sulfur cluster binding
EA719_002035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EA719_002035	COG1017	nitric oxide dioxygenase activity
EA719_002040	COG0433	COG0433 Predicted ATPase
EA719_002045	COG0626	cystathionine gamma-synthase activity
EA719_002165	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EA719_002175	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EA719_002200	COG1960	acyl-CoA dehydrogenase activity
EA719_002205	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EA719_002235	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EA719_002240	COG0339	signal peptide processing
EA719_002245	COG0557	exoribonuclease II activity
EA719_002290	COG0179	Fumarylacetoacetate (FAA) hydrolase
EA719_002295	COG2169	Transcriptional regulator
EA719_002300	COG0697	spore germination
EA719_002305	COG1295	ribonuclease BN
EA719_002340	COG1702	phosphate starvation-inducible protein PhoH
EA719_002350	COG0739	heme binding
EA719_002350	COG1196	nuclear chromosome segregation
EA719_002350	COG0741	lytic transglycosylase activity
EA719_002380	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EA719_002385	COG1183	phosphatidylcholine synthase activity
EA719_002430	COG1960	acyl-CoA dehydrogenase activity
EA719_002435	COG1309	transcriptional regulator
EA719_002450	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EA719_002455	COG1960	acyl-CoA dehydrogenase activity
EA719_002475	COG2969	positive regulation of protein catabolic process
EA719_002485	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EA719_002500	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EA719_002505	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EA719_002525	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EA719_002535	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EA719_002540	COG1408	metallophosphoesterase
EA719_002550	COG2199	diguanylate cyclase activity
EA719_002595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EA719_002595	COG3453	Protein conserved in bacteria
EA719_002610	COG1607	acyl-coa hydrolase
EA719_002640	COG2350	Protein conserved in bacteria
EA719_002650	COG0613	PHP domain protein
EA719_002655	COG3781	membrane
EA719_002665	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EA719_002670	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EA719_002680	COG1862	Preprotein translocase
EA719_002730	COG2205	protein histidine kinase activity
EA719_002735	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EA719_002755	COG0726	polysaccharide deacetylase
EA719_002760	COG0463	Glycosyl transferase, family 2
EA719_002765	COG0438	transferase activity, transferring glycosyl groups
EA719_002830	COG0625	glutathione transferase activity
EA719_002835	COG0583	DNA-binding transcription factor activity
EA719_002840	COG1960	acyl-CoA dehydrogenase activity
EA719_002845	COG1960	acyl-CoA dehydrogenase activity
EA719_002855	COG2205	protein histidine kinase activity
EA719_002860	COG0745	RESPONSE REGULATOR receiver
EA719_002865	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EA719_002885	COG2096	Adenosyltransferase
EA719_002900	COG0133	tryptophan synthase activity
EA719_002935	COG0285	dihydrofolate synthase activity
EA719_002955	COG0450	alkyl hydroperoxide reductase
EA719_002970	COG0477	Major facilitator Superfamily
EA719_002975	COG1272	protein, Hemolysin III
EA719_003005	COG0183	Belongs to the thiolase family
EA719_003010	COG2207	Transcriptional regulator
EA719_003030	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EA719_003050	COG0183	Belongs to the thiolase family
EA719_003060	COG2885	chlorophyll binding
EA719_003060	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EA719_003070	COG1690	Belongs to the RtcB family
EA719_003075	COG0833	amino acid
EA719_003085	COG2233	PERMEase
EA719_003115	COG2094	Belongs to the DNA glycosylase MPG family
EA719_003120	COG4772	TonB-dependent receptor
EA719_003135	COG1902	pentaerythritol trinitrate reductase activity
EA719_003140	COG0679	Auxin Efflux Carrier
EA719_003150	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EA719_003155	COG0354	folic acid binding
EA719_003165	COG3189	MarR family transcriptional regulator
EA719_003170	COG2824	Alkylphosphonate utilization operon protein PhnA
EA719_003175	COG3422	double-strand break repair
EA719_003215	COG0840	transmembrane signaling receptor activity
EA719_003235	COG5510	response to toxic substance
EA719_003245	COG2832	Protein of unknown function (DUF454)
EA719_003250	COG1376	ErfK ybiS ycfS ynhG family protein
EA719_003300	COG1289	transmembrane transporter activity
EA719_003305	COG2814	Major facilitator Superfamily
EA719_003325	COG1115	amino acid carrier protein
EA719_003330	COG1752	Esterase of the alpha-beta hydrolase superfamily
EA719_003335	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EA719_003340	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EA719_003370	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EA719_003380	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EA719_003385	COG1077	Cell shape determining protein MreB Mrl
EA719_003390	COG1792	Involved in formation and maintenance of cell shape
EA719_003395	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EA719_003400	COG0424	maF-like protein
EA719_003405	COG1530	ribonuclease E activity
EA719_003415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EA719_003435	COG2249	NAD(P)H dehydrogenase (quinone) activity
EA719_003460	COG2207	Transcriptional regulator
EA719_003480	COG1113	amino acid transport
EA719_003485	COG2828	Protein conserved in bacteria
EA719_003490	COG0142	geranyltranstransferase activity
EA719_003495	COG2315	Protein conserved in bacteria
EA719_003510	COG1752	Esterase of the alpha-beta hydrolase superfamily
EA719_003530	COG2194	sulfuric ester hydrolase activity
EA719_003535	COG0745	RESPONSE REGULATOR receiver
EA719_003540	COG0642	Histidine kinase
EA719_003550	COG0004	ammonium transporteR
EA719_003560	COG0583	DNA-binding transcription factor activity
EA719_003580	COG0525	valine-tRNA ligase activity
EA719_003590	COG1028	Short-chain dehydrogenase reductase Sdr
EA719_003600	COG0393	Putative heavy-metal-binding
EA719_003605	COG0393	Putative heavy-metal-binding
EA719_003610	COG1538	Outer membrane efflux protein
EA719_003620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA719_003625	COG0671	phosphoesterase, PA-phosphatase related
EA719_003655	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EA719_003670	COG1648	precorrin-2 dehydrogenase activity
EA719_003670	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EA719_003675	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EA719_003680	COG1733	regulation of RNA biosynthetic process
EA719_003690	COG0531	amino acid
EA719_003705	COG0321	lipoyl(octanoyl) transferase activity
EA719_003710	COG2921	Belongs to the UPF0250 family
EA719_003755	COG2009	succinate dehydrogenase
EA719_003760	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EA719_003765	COG1053	succinate dehydrogenase
EA719_003770	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EA719_003795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EA719_003815	COG2354	Protein conserved in bacteria
EA719_003820	COG2321	neutral zinc metallopeptidase
EA719_003895	COG2843	Capsule synthesis protein
EA719_003910	COG0589	response to stress
EA719_003930	COG0505	Belongs to the CarA family
EA719_003955	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EA719_003960	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EA719_004010	COG0477	Major facilitator Superfamily
EA719_004015	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EA719_004035	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EA719_004060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EA719_004065	COG0584	glycerophosphoryl diester phosphodiesterase
EA719_004085	COG0741	lytic transglycosylase activity
EA719_004110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EA719_004125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EA719_004155	COG0778	Nitroreductase
EA719_004170	COG1929	Belongs to the glycerate kinase type-1 family
EA719_004175	COG0243	molybdopterin cofactor binding
EA719_004180	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EA719_004185	COG3339	Conserved Protein
EA719_004195	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EA719_004210	COG1113	amino acid transport
EA719_004220	COG0019	diaminopimelate decarboxylase activity
EA719_004230	COG1280	lysine exporter protein (LysE YggA)
EA719_004235	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EA719_004265	COG0463	Glycosyl transferase, family 2
EA719_004285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA719_004315	COG4591	ABC-type transport system involved in lipoprotein release permease component
EA719_004320	COG1136	(ABC) transporter
EA719_004325	COG0658	competence protein
EA719_004325	COG2333	competence protein COMEC
EA719_004335	COG0616	signal peptide processing
EA719_004335	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EA719_004340	COG0596	Alpha beta hydrolase
EA719_004345	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EA719_004355	COG0628	permease
EA719_004390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EA719_004410	COG0823	Involved in the tonB-independent uptake of proteins
EA719_004430	COG0824	Thioesterase
EA719_004435	COG1473	amidohydrolase
EA719_004455	COG0047	phosphoribosylformylglycinamidine synthase activity
EA719_004455	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EA719_004460	COG2814	Major facilitator Superfamily
EA719_004465	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EA719_004470	COG1024	Enoyl-CoA hydratase
EA719_004475	COG1056	cytidyltransferase-related domain
EA719_004475	COG1051	belongs to the nudix hydrolase family
EA719_004485	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EA719_004500	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EA719_004515	COG4625	pathogenesis
EA719_004530	COG0583	DNA-binding transcription factor activity
EA719_004535	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EA719_004540	COG4208	sulfate ABC transporter
EA719_004545	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EA719_004555	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EA719_004560	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EA719_004565	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EA719_004585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EA719_004600	COG0681	Belongs to the peptidase S26 family
EA719_004615	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EA719_004625	COG1381	Involved in DNA repair and RecF pathway recombination
EA719_004630	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EA719_004640	COG4221	oxidoreductase activity
EA719_004690	COG0556	nucleotide-excision repair
EA719_004745	COG2070	2-Nitropropane dioxygenase
EA719_004775	COG1215	transferase activity, transferring glycosyl groups
EA719_004790	COG0415	Belongs to the DNA photolyase family
EA719_004800	COG1252	NADH dehydrogenase
EA719_004805	COG1686	Belongs to the peptidase S11 family
EA719_004820	COG1187	pseudouridine synthase activity
EA719_004845	COG0477	Major facilitator Superfamily
EA719_004850	COG0583	DNA-binding transcription factor activity
EA719_004865	COG0612	Peptidase, M16
EA719_004890	COG0352	thiamine-phosphate diphosphorylase activity
EA719_004925	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EA719_004940	COG1309	transcriptional regulator
EA719_004950	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EA719_004955	COG0076	glutamate decarboxylase activity
EA719_004965	COG1522	sequence-specific DNA binding
EA719_004970	COG3961	Belongs to the TPP enzyme family
EA719_004975	COG1113	amino acid transport
EA719_004980	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EA719_004985	COG0573	inorganic phosphate transmembrane transporter activity
EA719_004995	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EA719_005000	COG0616	signal peptide processing
EA719_005035	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EA719_005040	COG1686	Belongs to the peptidase S11 family
EA719_005065	COG0583	DNA-binding transcription factor activity
EA719_005070	COG1067	ATP-dependent peptidase activity
EA719_005115	COG1966	Carbon starvation protein
EA719_005120	COG2879	small protein
EA719_005155	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EA719_005155	COG2508	Transcriptional regulator
EA719_005175	COG1113	amino acid transport
EA719_005180	COG0583	DNA-binding transcription factor activity
EA719_005185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EA719_005190	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EA719_005205	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EA719_005210	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EA719_005210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EA719_005245	COG2814	Major facilitator Superfamily
EA719_005250	COG4948	Mandelate Racemase Muconate Lactonizing
EA719_005260	COG1309	transcriptional regulator
EA719_005280	COG1741	Belongs to the pirin family
EA719_005290	COG2964	Protein conserved in bacteria
EA719_005305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EA719_005310	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EA719_005315	COG4605	iron ion homeostasis
EA719_005320	COG4604	ABC transporter, ATP-binding protein
EA719_005325	COG4607	ABC-type enterochelin transport system periplasmic component
EA719_005330	COG4774	siderophore transport
EA719_005340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EA719_005345	COG1021	2,3-dihydroxybenzoate-AMP ligase
EA719_005350	COG3433	isochorismatase activity
EA719_005350	COG1535	isochorismatase
EA719_005365	COG1132	(ABC) transporter
EA719_005375	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EA719_005385	COG1169	isochorismate synthase
EA719_005400	COG3739	integral membrane protein
EA719_005435	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EA719_005465	COG0308	aminopeptidase N
EA719_005470	COG0512	Glutamine amidotransferase of anthranilate synthase
EA719_005480	COG3104	oligopeptide transport
EA719_005495	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EA719_005530	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EA719_005535	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EA719_005540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EA719_005560	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EA719_005565	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EA719_005570	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EA719_005585	COG1960	acyl-CoA dehydrogenase activity
EA719_005590	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EA719_005595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EA719_005605	COG2223	nitrite transmembrane transporter activity
EA719_005615	COG0024	Methionine aminopeptidase
EA719_005620	COG0052	Belongs to the universal ribosomal protein uS2 family
EA719_005635	COG2207	Transcriptional regulator
EA719_005660	COG2951	lytic endotransglycosylase activity
EA719_005665	COG0772	Belongs to the SEDS family
EA719_005680	COG0842	Transport permease protein
EA719_005685	COG1131	(ABC) transporter
EA719_005720	COG1538	Outer membrane efflux protein
EA719_005730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA719_005745	COG4215	(ABC) transporter
EA719_005750	COG4160	amino acid transport
EA719_005755	COG4598	ABC transporter
EA719_005765	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EA719_005775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EA719_005790	COG1720	tRNA m6t6A37 methyltransferase activity
EA719_005810	COG0745	RESPONSE REGULATOR receiver
EA719_005815	COG0642	Histidine kinase
EA719_005825	COG0494	nUDIX hydrolase
EA719_005835	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EA719_005840	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EA719_005845	COG3139	Protein of unknown function (DUF1315)
EA719_005850	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EA719_005860	COG1301	dicarboxylic acid transport
EA719_005865	COG1960	acyl-CoA dehydrogenase activity
EA719_005870	COG2819	hydrolase of the alpha beta superfamily
EA719_005880	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EA719_005890	COG2195	Cleaves the N-terminal amino acid of tripeptides
EA719_005895	COG1234	tRNA 3'-trailer cleavage
EA719_005925	COG2363	Small membrane protein
EA719_005945	COG0513	Belongs to the DEAD box helicase family
EA719_005955	COG0778	Nitroreductase
EA719_005985	COG1286	toxin biosynthetic process
EA719_006010	COG4783	chaperone-mediated protein folding
EA719_006015	COG1610	YqeY-like protein
EA719_006020	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EA719_006115	COG3111	PFAM Bacterial OB fold (BOF) protein
EA719_006140	COG3243	poly(R)-hydroxyalkanoic acid synthase
EA719_006145	COG0786	glutamate:sodium symporter activity
EA719_006155	COG2186	Transcriptional regulator
EA719_006215	COG3316	Transposase and inactivated derivatives
EA719_006270	COG0482	sulfurtransferase activity
EA719_006290	COG3173	Aminoglycoside phosphotransferase
EA719_006300	COG2433	Pfam Transposase IS66
EA719_006325	COG3316	Transposase and inactivated derivatives
EA719_006345	COG1301	dicarboxylic acid transport
EA719_006355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EA719_006360	COG2011	ABC-type metal ion transport system permease component
EA719_006365	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EA719_006370	COG1464	Belongs to the NlpA lipoprotein family
EA719_006375	COG0151	Belongs to the GarS family
EA719_006380	COG0138	bifunctional purine biosynthesis protein purh
EA719_006385	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EA719_006415	COG2308	Evidence 4 Homologs of previously reported genes of
EA719_006425	COG1305	Transglutaminase-like
EA719_006435	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EA719_006440	COG0305	Participates in initiation and elongation during chromosome replication
EA719_006465	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EA719_006475	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EA719_006480	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EA719_006505	COG0726	polysaccharide deacetylase
EA719_006505	COG1649	PFAM Uncharacterised BCR, COG1649
EA719_006510	COG1215	transferase activity, transferring glycosyl groups
EA719_006515	COG3658	cytochrome
EA719_006525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EA719_006545	COG0583	DNA-binding transcription factor activity
EA719_006565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EA719_006570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EA719_006585	COG1960	acyl-CoA dehydrogenase activity
EA719_006590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EA719_006595	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EA719_006620	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EA719_006625	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EA719_006635	COG2205	protein histidine kinase activity
EA719_006640	COG0745	RESPONSE REGULATOR receiver
EA719_006645	COG0174	glutamine synthetase
EA719_006665	COG0729	surface antigen
EA719_006695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EA719_006700	COG2814	Major facilitator Superfamily
EA719_006715	COG0583	DNA-binding transcription factor activity
EA719_006730	COG1187	pseudouridine synthase activity
EA719_006750	COG0802	atpase or kinase
EA719_006755	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EA719_006765	COG1923	regulation of RNA biosynthetic process
EA719_006770	COG0697	spore germination
EA719_006785	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EA719_006800	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EA719_006800	COG0519	Catalyzes the synthesis of GMP from XMP
EA719_006805	COG4302	ethanolamine ammonia-lyase activity
EA719_006810	COG4303	Ethanolamine ammonia lyase large subunit
EA719_006815	COG0531	amino acid
EA719_006835	COG1454	alcohol dehydrogenase
EA719_006840	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EA719_006850	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EA719_006870	COG0308	aminopeptidase N
EA719_006880	COG4221	oxidoreductase activity
EA719_006890	COG1605	Chorismate mutase
EA719_006910	COG1309	transcriptional regulator
EA719_006920	COG0668	transmembrane transport
EA719_006955	COG4773	Receptor
EA719_006975	COG0488	(ABC) transporter
EA719_006980	COG0589	response to stress
EA719_006995	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EA719_007005	COG3135	benzoate transporter
EA719_007010	COG1522	sequence-specific DNA binding
EA719_007025	COG0583	DNA-binding transcription factor activity
EA719_007035	COG0183	Belongs to the thiolase family
EA719_007065	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EA719_007075	COG0824	Thioesterase
EA719_007080	COG1454	alcohol dehydrogenase
EA719_007090	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EA719_007110	COG0069	glutamate synthase activity
EA719_007260	COG1598	PFAM Uncharacterised protein family UPF0150
EA719_007295	COG0739	heme binding
EA719_007390	COG2814	Major facilitator Superfamily
EA719_007435	COG0589	response to stress
EA719_007440	COG0659	secondary active sulfate transmembrane transporter activity
EA719_007455	COG1061	Type III restriction enzyme res subunit
EA719_007485	COG0511	ligase activity, forming carbon-carbon bonds
EA719_007505	COG1116	anion transmembrane transporter activity
EA719_007505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EA719_007510	COG0745	RESPONSE REGULATOR receiver
EA719_007520	COG2146	nitrite reductase [NAD(P)H] activity
EA719_007520	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EA719_007525	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EA719_007530	COG0243	molybdopterin cofactor binding
EA719_007540	COG0243	molybdopterin cofactor binding
EA719_007545	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EA719_007560	COG0521	Mo-molybdopterin cofactor biosynthetic process
EA719_007560	COG0315	cyclic pyranopterin monophosphate synthase activity
EA719_007565	COG0303	'Molybdopterin
EA719_007575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EA719_007580	COG0697	spore germination
EA719_007600	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EA719_007605	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EA719_007680	COG2204	response regulator
EA719_007685	COG3852	Histidine kinase
EA719_007710	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EA719_007715	COG0575	Belongs to the CDS family
EA719_007750	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EA719_007765	COG2137	regulation of response to DNA damage stimulus
EA719_007775	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EA719_007780	COG1011	Hydrolase
EA719_007805	COG1522	sequence-specific DNA binding
EA719_007815	COG1113	amino acid transport
EA719_007830	COG0659	secondary active sulfate transmembrane transporter activity
EA719_007835	COG2135	peptidase activity
EA719_007850	COG3300	MHYT domain
EA719_007850	COG5001	Diguanylate cyclase
EA719_007870	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EA719_007870	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EA719_007870	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EA719_007875	COG1105	Belongs to the carbohydrate kinase PfkB family
EA719_007880	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EA719_007880	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EA719_007910	COG0024	Methionine aminopeptidase
EA719_007915	COG0583	DNA-binding transcription factor activity
EA719_007925	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EA719_007930	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EA719_007935	COG0517	IMP dehydrogenase activity
EA719_007935	COG0516	GMP reductase activity
EA719_007960	COG0552	protein localization to endoplasmic reticulum
EA719_007970	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EA719_007985	COG4890	Cyd operon protein YbgT
EA719_007990	COG1294	oxidase, subunit
EA719_008005	COG1585	Membrane protein implicated in regulation of membrane protease activity
EA719_008015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EA719_008020	COG4774	siderophore transport
EA719_008035	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EA719_008040	COG0569	domain protein
EA719_008045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EA719_008075	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EA719_008080	COG0542	response to heat
EA719_008090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EA719_008105	COG0446	pyridine nucleotide-disulphide oxidoreductase
EA719_008105	COG1902	pentaerythritol trinitrate reductase activity
EA719_008150	COG2323	membrane
EA719_008155	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EA719_008165	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EA719_008170	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EA719_008175	COG0183	Belongs to the thiolase family
EA719_008180	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EA719_008185	COG0596	Alpha beta hydrolase
EA719_008190	COG2271	Major facilitator Superfamily
EA719_008195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EA719_008200	COG3485	protocatechuate 3,4-dioxygenase
EA719_008205	COG3485	protocatechuate 3,4-dioxygenase
EA719_008210	COG0710	3-dehydroquinate dehydratase activity
EA719_008215	COG3420	alginic acid biosynthetic process
EA719_008220	COG3659	wide pore channel activity
EA719_008225	COG4993	Dehydrogenase
EA719_008235	COG2391	methyltransferase activity
EA719_008250	COG1414	Transcriptional regulator
EA719_008255	COG0583	DNA-binding transcription factor activity
EA719_008260	COG1960	acyl-CoA dehydrogenase activity
EA719_008285	COG2814	Major facilitator Superfamily
EA719_008295	COG0154	amidase activity
EA719_008315	COG4638	Rieske (2fe-2S)
EA719_008325	COG1028	Short-chain dehydrogenase reductase Sdr
EA719_008335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EA719_008345	COG3733	amine oxidase
EA719_008355	COG1012	belongs to the aldehyde dehydrogenase family
EA719_008365	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EA719_008370	COG0183	Belongs to the thiolase family
EA719_008375	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EA719_008380	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EA719_008390	COG4829	muconolactone delta-isomerase
EA719_008395	COG4948	Mandelate Racemase Muconate Lactonizing
EA719_008400	COG0583	DNA-binding transcription factor activity
EA719_008410	COG2186	Transcriptional regulator
EA719_008430	COG1012	belongs to the aldehyde dehydrogenase family
EA719_008450	COG1960	acyl-CoA dehydrogenase activity
EA719_008460	COG3829	transcription factor binding
EA719_008470	COG3162	membrane
EA719_008485	COG1012	belongs to the aldehyde dehydrogenase family
EA719_008500	COG0753	catalase activity
EA719_008525	COG1846	Transcriptional regulator
EA719_008530	COG0446	pyridine nucleotide-disulphide oxidoreductase
EA719_008530	COG1902	pentaerythritol trinitrate reductase activity
EA719_008540	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EA719_008570	COG1309	transcriptional regulator
EA719_008580	COG1335	isochorismatase
EA719_008585	COG0583	DNA-binding transcription factor activity
EA719_008595	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EA719_008595	COG0475	glutathione-regulated potassium exporter activity
EA719_008605	COG1473	amidohydrolase
EA719_008620	COG2831	hemolysin activation secretion protein
EA719_008625	COG3210	domain, Protein
EA719_008680	COG0583	DNA-binding transcription factor activity
EA719_008705	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EA719_008710	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EA719_008730	COG1566	PFAM secretion protein HlyD family protein
EA719_008745	COG1012	belongs to the aldehyde dehydrogenase family
EA719_008750	COG0129	dihydroxy-acid dehydratase activity
EA719_008760	COG0583	DNA-binding transcription factor activity
EA719_008765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EA719_008775	COG2084	Dehydrogenase
EA719_008780	COG2207	Transcriptional regulator
EA719_008795	COG1064	alcohol dehydrogenase
EA719_008810	COG1120	ATPase activity
EA719_008830	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EA719_008950	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EA719_009005	COG1028	Short-chain dehydrogenase reductase Sdr
EA719_009020	COG2207	Transcriptional regulator
EA719_009030	COG2205	protein histidine kinase activity
EA719_009035	COG0745	RESPONSE REGULATOR receiver
EA719_009040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA719_009045	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EA719_009050	COG1538	Outer membrane efflux protein
EA719_009060	COG2072	flavoprotein involved in K transport
EA719_009080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EA719_009100	COG3539	Fimbrial protein
EA719_009130	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EA719_009140	COG0753	catalase activity
EA719_009155	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EA719_009220	COG1535	isochorismatase
EA719_009220	COG3433	isochorismatase activity
EA719_009225	COG1028	Short-chain dehydrogenase reductase Sdr
EA719_009230	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EA719_009235	COG4149	molybdate abc transporter
EA719_009240	COG0725	ABC transporter, periplasmic molybdate-binding protein
EA719_009250	COG4638	Rieske (2fe-2S)
EA719_009255	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EA719_009260	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EA719_009260	COG0543	2 iron, 2 sulfur cluster binding
EA719_009275	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EA719_009285	COG1028	Short-chain dehydrogenase reductase Sdr
EA719_009290	COG0412	Dienelactone hydrolase
EA719_009300	COG2207	Transcriptional regulator
EA719_009310	COG1028	Short-chain dehydrogenase reductase Sdr
EA719_009315	COG2610	gluconate transmembrane transporter activity
EA719_009325	COG0583	DNA-binding transcription factor activity
EA719_009335	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EA719_009340	COG2031	fatty acid transporter
EA719_009345	COG0183	Belongs to the thiolase family
EA719_009350	COG0583	DNA-binding transcription factor activity
EA719_009355	COG0583	DNA-binding transcription factor activity
EA719_009370	COG1027	Aspartate ammonia-lyase
EA719_009380	COG0477	Major facilitator Superfamily
EA719_009400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EA719_009405	COG4521	taurine ABC transporter
EA719_009430	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EA719_009435	COG1733	regulation of RNA biosynthetic process
EA719_009440	COG3708	Transcriptional regulator
EA719_009440	COG2207	Transcriptional regulator
EA719_009455	COG0730	response to heat
EA719_009465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EA719_009465	COG3453	Protein conserved in bacteria
EA719_009475	COG3781	membrane
EA719_009480	COG1063	alcohol dehydrogenase
EA719_009490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EA719_009495	COG0508	dehydrogenase complex catalyzes the overall conversion of
EA719_009500	COG0022	dehydrogenase e1 component
EA719_009505	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EA719_009510	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EA719_009525	COG3706	GGDEF domain
EA719_009540	COG0133	tryptophan synthase activity
EA719_009550	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EA719_009585	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EA719_009610	COG2226	methyltransferase
EA719_009665	COG0842	Transport permease protein
EA719_009670	COG0842	Transport permease protein
EA719_009675	COG1131	(ABC) transporter
EA719_009690	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EA719_009695	COG4773	Receptor
EA719_009715	COG0730	response to heat
EA719_009720	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EA719_009740	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EA719_009800	COG4264	IucA IucC family
EA719_009805	COG4264	IucA IucC family
EA719_009825	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EA719_009840	COG1960	acyl-CoA dehydrogenase activity
EA719_009845	COG1960	acyl-CoA dehydrogenase activity
EA719_009850	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EA719_009855	COG2207	Transcriptional regulator
EA719_009860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EA719_009865	COG0776	regulation of translation
EA719_009890	COG0822	iron-sulfur transferase activity
EA719_009895	COG0316	Belongs to the HesB IscA family
EA719_009925	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EA719_009945	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EA719_009950	COG0702	epimerase
EA719_009985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EA719_009995	COG0339	signal peptide processing
EA719_010045	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EA719_010050	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EA719_010080	COG0776	regulation of translation
EA719_010100	COG0590	tRNA wobble adenosine to inosine editing
EA719_010130	COG2165	general secretion pathway protein
EA719_010145	COG0084	hydrolase, TatD family'
EA719_010165	COG1663	tetraacyldisaccharide 4'-kinase activity
EA719_010170	COG1132	(ABC) transporter
EA719_010180	COG0811	peptide transport
EA719_010185	COG1475	DNA binding
EA719_010190	COG1192	Involved in chromosome partitioning
EA719_010200	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EA719_010215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EA719_010220	COG0191	fructose-bisphosphate aldolase activity
EA719_010240	COG0424	maF-like protein
EA719_010245	COG2850	peptidyl-arginine hydroxylation
EA719_010255	COG0640	Transcriptional regulator
EA719_010265	COG3619	membrane
EA719_010270	COG3122	Protein conserved in bacteria
EA719_010275	COG1132	(ABC) transporter
EA719_010295	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EA719_010300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EA719_010310	COG0506	proline dehydrogenase activity
EA719_010310	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EA719_010310	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EA719_010315	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EA719_010330	COG3698	Phosphodiester glycosidase
EA719_010345	COG1765	OsmC-like protein
EA719_010360	COG2353	YceI-like domain
EA719_010370	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EA719_010415	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EA719_010415	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EA719_010440	COG3539	Fimbrial protein
EA719_010445	COG3121	Chaperone
EA719_010475	COG0697	spore germination
EA719_010485	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EA719_010495	COG0583	DNA-binding transcription factor activity
EA719_010515	COG1309	transcriptional regulator
EA719_010525	COG1126	abc transporter atp-binding protein
EA719_010530	COG0765	amino acid transport
EA719_010535	COG0765	amino acid transport
EA719_010565	COG1464	Belongs to the NlpA lipoprotein family
EA719_010575	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EA719_010580	COG2011	ABC-type metal ion transport system permease component
EA719_010585	COG0012	GTP binding
EA719_010610	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EA719_010650	COG0386	Belongs to the glutathione peroxidase family
EA719_010660	COG0436	Aminotransferase
EA719_010700	COG3634	alkyl hydroperoxide reductase activity
EA719_010715	COG0583	DNA-binding transcription factor activity
EA719_010720	COG0798	PFAM Bile acid sodium symporter
EA719_010725	COG0640	Transcriptional regulator
EA719_010740	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EA719_010750	COG0583	DNA-binding transcription factor activity
EA719_010760	COG1953	Uracil, thiamine, allantoin
EA719_010770	COG2175	clavaminate synthase activity
EA719_010775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EA719_010780	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EA719_010785	COG4521	taurine ABC transporter
EA719_010795	COG0477	Major facilitator Superfamily
EA719_010820	COG1271	oxidase subunit
EA719_010825	COG1294	oxidase, subunit
EA719_010835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EA719_010855	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EA719_010875	COG3052	prosthetic group binding
EA719_010880	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
EA719_010890	COG2814	Major facilitator Superfamily
EA719_010910	COG1346	cytolysis
EA719_010920	COG0583	DNA-binding transcription factor activity
EA719_010925	COG0625	glutathione transferase activity
EA719_010930	COG0625	glutathione transferase activity
EA719_010935	COG0583	DNA-binding transcription factor activity
EA719_010950	COG1045	serine acetyltransferase
EA719_010955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EA719_010960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EA719_010970	COG1280	lysine exporter protein (LysE YggA)
EA719_010985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EA719_010990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EA719_010995	COG1126	abc transporter atp-binding protein
EA719_011000	COG0765	amino acid transport
EA719_011005	COG0765	amino acid transport
EA719_011025	COG0784	Response regulator, receiver
EA719_011025	COG2205	protein histidine kinase activity
EA719_011045	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EA719_011065	COG1028	Short-chain dehydrogenase reductase Sdr
EA719_011110	COG0583	DNA-binding transcription factor activity
EA719_011130	COG0318	PFAM AMP-dependent synthetase and ligase
EA719_011135	COG1309	transcriptional regulator
EA719_011140	COG1960	acyl-CoA dehydrogenase activity
EA719_011145	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EA719_011150	COG1024	Enoyl-CoA hydratase
EA719_011165	COG0583	DNA-binding transcription factor activity
EA719_011180	COG1960	acyl-CoA dehydrogenase activity
EA719_011190	COG2814	Major facilitator Superfamily
EA719_011200	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EA719_011205	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EA719_011210	COG2814	Major facilitator Superfamily
EA719_011215	COG1960	acyl-CoA dehydrogenase activity
EA719_011220	COG1024	Enoyl-CoA hydratase
EA719_011225	COG1028	Short-chain dehydrogenase reductase Sdr
EA719_011230	COG1250	3-hydroxyacyl-CoA dehydrogenase
EA719_011235	COG0183	Belongs to the thiolase family
EA719_011245	COG2814	Major facilitator Superfamily
EA719_011255	COG1024	Enoyl-CoA hydratase
EA719_011270	COG1960	acyl-CoA dehydrogenase activity
EA719_011275	COG2814	Major facilitator Superfamily
EA719_011280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EA719_011285	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EA719_011300	COG3842	ATPase activity
EA719_011305	COG1840	ABC-type Fe3 transport system, periplasmic component
EA719_011315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EA719_011320	COG1414	Transcriptional regulator
EA719_011330	COG0583	DNA-binding transcription factor activity
EA719_011335	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EA719_011340	COG1012	belongs to the aldehyde dehydrogenase family
EA719_011350	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EA719_011360	COG1012	belongs to the aldehyde dehydrogenase family
EA719_011365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EA719_011370	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EA719_011375	COG2267	carboxylic ester hydrolase activity
EA719_011395	COG3038	cytochrome b561
EA719_011400	COG0753	catalase activity
EA719_011440	COG2050	protein possibly involved in aromatic compounds catabolism
EA719_011450	COG3327	negative regulation of DNA-templated transcription, initiation
EA719_011455	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EA719_011460	COG0183	Belongs to the thiolase family
EA719_011465	COG1250	3-hydroxyacyl-CoA dehydrogenase
EA719_011470	COG1024	Enoyl-CoA hydratase
EA719_011475	COG1024	Enoyl-CoA hydratase
EA719_011480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EA719_011485	COG2151	metal-sulfur cluster biosynthetic enzyme
EA719_011490	COG3396	Phenylacetate-CoA oxygenase
EA719_011495	COG3460	Phenylacetate-CoA oxygenase
EA719_011500	COG3396	Phenylacetate-CoA oxygenase
EA719_011505	COG1012	belongs to the aldehyde dehydrogenase family
EA719_011505	COG2030	dehydratase
EA719_011510	COG1760	l-serine dehydratase
EA719_011515	COG0531	amino acid
EA719_011520	COG1012	belongs to the aldehyde dehydrogenase family
EA719_011535	COG0446	pyridine nucleotide-disulphide oxidoreductase
EA719_011545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EA719_011565	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EA719_011580	COG0789	Transcriptional regulator
EA719_011595	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EA719_011610	COG2807	transmembrane transport
EA719_011615	COG0590	tRNA wobble adenosine to inosine editing
EA719_011625	COG0583	DNA-binding transcription factor activity
EA719_011665	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EA719_011665	COG2885	chlorophyll binding
EA719_011695	COG1765	OsmC-like protein
EA719_011760	COG1116	anion transmembrane transporter activity
EA719_011765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EA719_011775	COG0864	Transcriptional regulator
EA719_011795	COG2249	NAD(P)H dehydrogenase (quinone) activity
EA719_011800	COG0439	Biotin carboxylase
EA719_011815	COG1063	alcohol dehydrogenase
EA719_011825	COG1309	transcriptional regulator
EA719_011850	COG0038	chloride channel
EA719_011855	COG4770	biotin carboxylase activity
EA719_011875	COG1914	H( )-stimulated, divalent metal cation uptake system
EA719_011880	COG0583	DNA-binding transcription factor activity
EA719_011895	COG3209	COG3209 Rhs family protein
EA719_011900	COG3501	Rhs element vgr protein
EA719_011935	COG1250	3-hydroxyacyl-CoA dehydrogenase
EA719_011955	COG2814	Major facilitator Superfamily
EA719_011970	COG1560	Kdo2-lipid A biosynthetic process
EA719_011980	COG5006	permease, DMT superfamily
EA719_011985	COG1522	sequence-specific DNA binding
EA719_012000	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EA719_012040	COG1538	Outer membrane efflux protein
EA719_012045	COG1137	ATPase activity
EA719_012050	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EA719_012060	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EA719_012065	COG0517	IMP dehydrogenase activity
EA719_012065	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EA719_012100	COG1733	regulation of RNA biosynthetic process
EA719_012105	COG2814	Major facilitator Superfamily
EA719_012145	COG1278	Cold shock
EA719_012150	COG1280	lysine exporter protein (LysE YggA)
EA719_012185	COG1570	exodeoxyribonuclease VII activity
EA719_012240	COG0583	DNA-binding transcription factor activity
EA719_012245	COG4638	Rieske (2fe-2S)
EA719_012250	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EA719_012255	COG0633	Ferredoxin
EA719_012255	COG0543	2 iron, 2 sulfur cluster binding
EA719_012260	COG1028	Short-chain dehydrogenase reductase Sdr
EA719_012265	COG3135	benzoate transporter
EA719_012270	COG2814	Major facilitator Superfamily
EA719_012285	COG1643	Atp-dependent helicase
EA719_012290	COG0450	alkyl hydroperoxide reductase
EA719_012300	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EA719_012310	COG3634	alkyl hydroperoxide reductase activity
EA719_012330	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EA719_012335	COG0625	glutathione transferase activity
EA719_012345	COG2885	chlorophyll binding
EA719_012400	COG1765	OsmC-like protein
EA719_012415	COG0667	Aldo Keto reductase
EA719_012430	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EA719_012440	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EA719_012460	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EA719_012470	COG3038	cytochrome b561
EA719_012475	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EA719_012480	COG2252	PERMEase
EA719_012490	COG2072	flavoprotein involved in K transport
EA719_012505	COG1741	Belongs to the pirin family
EA719_012510	COG1309	transcriptional regulator
EA719_012520	COG0300	oxidoreductase activity
EA719_012535	COG3316	Transposase and inactivated derivatives
EA719_012540	COG1113	amino acid transport
EA719_012560	COG1012	belongs to the aldehyde dehydrogenase family
EA719_012580	COG0531	amino acid
EA719_012590	COG1113	amino acid transport
EA719_012635	COG3209	COG3209 Rhs family protein
EA719_012640	COG3501	Rhs element vgr protein
EA719_012660	COG4269	membrane
EA719_012675	COG0446	pyridine nucleotide-disulphide oxidoreductase
EA719_012675	COG1902	pentaerythritol trinitrate reductase activity
EA719_012685	COG5001	Diguanylate cyclase
EA719_012685	COG4251	negative regulation of phosphorylation
EA719_012685	COG3706	GGDEF domain
EA719_012685	COG2203	Gaf domain
EA719_012695	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EA719_012715	COG4172	Belongs to the ABC transporter superfamily
EA719_012720	COG4239	(ABC) transporter, permease
EA719_012725	COG4174	ABC transporter (Permease)
EA719_012735	COG1388	LysM domain
EA719_012735	COG1388	LysM domain
EA719_012735	COG0741	lytic transglycosylase activity
EA719_012735	COG0741	lytic transglycosylase activity
EA719_012740	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EA719_012780	COG0583	DNA-binding transcription factor activity
EA719_012785	COG1279	arginine transmembrane transporter activity
EA719_012805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EA719_012810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EA719_012815	COG0006	proline dipeptidase activity
EA719_012850	COG2194	sulfuric ester hydrolase activity
EA719_012895	COG0739	heme binding
EA719_013220	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EA719_013245	COG3384	dioxygenase
EA719_013255	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EA719_013260	COG2878	Part of a membrane complex involved in electron transport
EA719_013265	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EA719_013290	COG0768	penicillin binding
EA719_013295	COG0742	ribosomal rna small subunit methyltransferase
EA719_013310	COG0830	nickel cation binding
EA719_013320	COG0804	urea catabolic process
EA719_013360	COG1253	flavin adenine dinucleotide binding
EA719_013420	COG1773	rubredoxin
EA719_013425	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EA719_013435	COG0583	DNA-binding transcription factor activity
EA719_013460	COG4181	ATPase activity
EA719_013505	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EA719_013525	COG0306	phosphate transporter
EA719_013535	COG3958	Transketolase
EA719_013540	COG3959	Transketolase, thiamine diphosphate binding domain
EA719_013545	COG2271	Major facilitator Superfamily
EA719_013550	COG1028	Short-chain dehydrogenase reductase Sdr
EA719_013555	COG0583	DNA-binding transcription factor activity
EA719_013575	COG2223	nitrite transmembrane transporter activity
EA719_013580	COG2207	Transcriptional regulator
EA719_013585	COG2066	Belongs to the glutaminase family
EA719_013590	COG0242	peptide deformylase activity
EA719_013595	COG0477	Major facilitator Superfamily
EA719_013605	COG0028	Belongs to the TPP enzyme family
EA719_013620	COG1028	Short-chain dehydrogenase reductase Sdr
EA719_013625	COG2267	carboxylic ester hydrolase activity
EA719_013635	COG2271	Major facilitator Superfamily
EA719_013640	COG0446	pyridine nucleotide-disulphide oxidoreductase
EA719_013650	COG1028	Short-chain dehydrogenase reductase Sdr
EA719_013670	COG1414	Transcriptional regulator
EA719_013685	COG1024	Enoyl-CoA hydratase
EA719_013695	COG1215	transferase activity, transferring glycosyl groups
EA719_013700	COG0726	polysaccharide deacetylase
EA719_013700	COG1649	PFAM Uncharacterised BCR, COG1649
EA719_013710	COG4681	YaeQ
EA719_013720	COG0523	cobalamin synthesis protein
EA719_013730	COG1607	acyl-coa hydrolase
EA719_013740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EA719_013745	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EA719_013750	COG1309	transcriptional regulator
EA719_013775	COG2040	homocysteine
EA719_013780	COG0531	amino acid
EA719_013805	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EA719_013810	COG0477	Major facilitator Superfamily
EA719_013930	COG0592	DNA-directed DNA polymerase activity
EA719_013970	COG2026	Addiction module toxin, RelE StbE family
EA719_014115	COG0405	Gamma-glutamyltransferase
EA719_014120	COG2814	Major facilitator Superfamily
EA719_014130	COG2050	protein possibly involved in aromatic compounds catabolism
EA719_014145	COG1090	epimerase
EA719_014165	COG0420	3'-5' exonuclease activity
EA719_014190	COG0735	belongs to the Fur family
EA719_014195	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EA719_014220	COG0121	glutamine amidotransferase
EA719_014235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EA719_014245	COG0210	DNA helicase
EA719_014250	COG2885	chlorophyll binding
EA719_014255	COG0204	Acyl-transferase
EA719_014270	COG2894	cell division
EA719_014290	COG1280	lysine exporter protein (LysE YggA)
EA719_014295	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EA719_014295	COG1674	ftsk spoiiie
EA719_014300	COG0492	ferredoxin-NADP+ reductase activity
EA719_014305	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EA719_014315	COG0456	acetyltransferase
EA719_014375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EA719_014375	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EA719_014395	COG1012	belongs to the aldehyde dehydrogenase family
EA719_014415	COG0473	3-isopropylmalate dehydrogenase activity
EA719_014420	COG0583	DNA-binding transcription factor activity
EA719_014440	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EA719_014465	COG0564	pseudouridine synthase activity
EA719_014475	COG0358	DNA primase activity
EA719_014490	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EA719_014520	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EA719_014550	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EA719_014560	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EA719_014560	COG0352	thiamine-phosphate diphosphorylase activity
EA719_014560	COG0351	phosphomethylpyrimidine kinase
EA719_014565	COG1652	LysM domain
EA719_014590	COG1399	metal-binding, possibly nucleic acid-binding protein
EA719_014595	COG3101	peptidyl-lysine hydroxylation
EA719_014600	COG0009	L-threonylcarbamoyladenylate synthase
EA719_014605	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EA719_014610	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EA719_014625	COG4106	trans-aconitate 2-methyltransferase activity
EA719_014640	COG0596	Alpha beta hydrolase
EA719_014640	COG2226	methyltransferase
EA719_014640	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EA719_014645	COG1877	trehalose-phosphatase activity
EA719_014650	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
EA719_014655	COG2223	nitrite transmembrane transporter activity
EA719_014675	COG1196	nuclear chromosome segregation
EA719_014685	COG0730	response to heat
EA719_014700	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EA719_014710	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EA719_014770	COG0489	protein tyrosine kinase activity
EA719_014780	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EA719_014780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EA719_014810	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EA719_014815	COG2081	HI0933 family
EA719_014825	COG0668	transmembrane transport
EA719_014845	COG0583	DNA-binding transcription factor activity
EA719_014865	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EA719_014870	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EA719_014900	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EA719_014935	COG2205	protein histidine kinase activity
EA719_014940	COG0745	RESPONSE REGULATOR receiver
EA719_014960	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EA719_014970	COG2205	protein histidine kinase activity
EA719_015040	COG4993	Dehydrogenase
EA719_015060	COG0384	phenazine biosynthesis protein PhzF
EA719_015090	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EA719_015095	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EA719_015105	COG0583	DNA-binding transcription factor activity
EA719_015125	COG1473	amidohydrolase
EA719_015135	COG0583	DNA-binding transcription factor activity
EA719_015155	COG0583	DNA-binding transcription factor activity
EA719_015160	COG1053	succinate dehydrogenase
EA719_015170	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EA719_015175	COG2814	Major facilitator Superfamily
EA719_015180	COG1960	acyl-CoA dehydrogenase activity
EA719_015185	COG0583	DNA-binding transcription factor activity
EA719_015190	COG1063	alcohol dehydrogenase
EA719_015220	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EA719_015225	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EA719_015230	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EA719_015245	COG3667	copper resistance
EA719_015250	COG2132	Multicopper oxidase
EA719_015260	COG0561	phosphatase activity
EA719_015265	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EA719_015290	COG1214	PFAM Peptidase M22, glycoprotease
EA719_015350	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EA719_015360	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EA719_015365	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EA719_015370	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EA719_015430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EA719_015440	COG1846	Transcriptional regulator
EA719_015445	COG1764	response to oxidative stress
EA719_015485	COG0037	tRNA processing
EA719_015495	COG0248	Ppx GppA phosphatase
EA719_015525	COG0072	phenylalanine-tRNA ligase activity
EA719_015550	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EA719_015565	COG1238	metal cluster binding
EA719_015570	COG0625	glutathione transferase activity
EA719_015590	COG0318	PFAM AMP-dependent synthetase and ligase
EA719_015595	COG3028	Belongs to the UPF0307 family
EA719_015600	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EA719_015620	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EA719_015625	COG0617	tRNA 3'-terminal CCA addition
EA719_015630	COG1555	photosystem II stabilization
EA719_015635	COG3956	TIGRFAM MazG family protein
EA719_015645	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EA719_015665	COG0784	Response regulator, receiver
EA719_015665	COG5002	protein histidine kinase activity
EA719_015665	COG2205	protein histidine kinase activity
EA719_015670	COG1024	Enoyl-CoA hydratase
EA719_015675	COG2084	Dehydrogenase
EA719_015680	COG3622	Belongs to the hyi family
EA719_015695	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EA719_015700	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EA719_015705	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EA719_015710	COG0697	spore germination
EA719_015720	COG2814	Major facilitator Superfamily
EA719_015725	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EA719_015735	COG0583	DNA-binding transcription factor activity
EA719_015745	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EA719_015760	COG0084	hydrolase, TatD family'
EA719_015775	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EA719_015810	COG0440	acetolactate synthase activity
EA719_015815	COG0028	Belongs to the TPP enzyme family
EA719_015840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA719_015845	COG0577	efflux transmembrane transporter activity
EA719_015845	COG1136	(ABC) transporter
EA719_015850	COG1538	Outer membrane efflux protein
EA719_015865	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EA719_015870	COG1162	GTPase activity
EA719_015880	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EA719_015900	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EA719_015905	COG1028	Short-chain dehydrogenase reductase Sdr
EA719_015945	COG2986	histidine ammonia-lyase
EA719_015960	COG0318	PFAM AMP-dependent synthetase and ligase
EA719_015970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EA719_015975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EA719_016015	COG1426	Protein conserved in bacteria
EA719_016050	COG0793	Belongs to the peptidase S41A family
EA719_016065	COG2267	carboxylic ester hydrolase activity
EA719_016075	COG1012	belongs to the aldehyde dehydrogenase family
EA719_016080	COG3265	gluconokinase activity
EA719_016090	COG0800	Aldolase
EA719_016100	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EA719_016105	COG0857	belongs to the CobB CobQ family
EA719_016105	COG0280	phosphate acetyltransferase
EA719_016110	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EA719_016110	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EA719_016130	COG0740	serine-type endopeptidase activity
EA719_016140	COG4774	siderophore transport
EA719_016150	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EA719_016160	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EA719_016160	COG2813	Specifically methylates the guanine in position
EA719_016260	COG0788	formyltetrahydrofolate deformylase activity
EA719_016275	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EA719_016280	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EA719_016285	COG4651	solute:proton antiporter activity
EA719_016285	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EA719_016305	COG0724	RNA recognition motif
EA719_016310	COG0210	DNA helicase
EA719_016335	COG1733	regulation of RNA biosynthetic process
EA719_016355	COG1280	lysine exporter protein (LysE YggA)
EA719_016360	COG1560	Kdo2-lipid A biosynthetic process
EA719_016370	COG1301	dicarboxylic acid transport
EA719_016425	COG0473	3-isopropylmalate dehydrogenase activity
EA719_016490	COG0583	DNA-binding transcription factor activity
EA719_016500	COG0625	glutathione transferase activity
EA719_016505	COG2378	regulation of single-species biofilm formation
EA719_016510	COG0546	phosphoglycolate phosphatase activity
EA719_016525	COG1530	ribonuclease E activity
EA719_016545	COG0583	DNA-binding transcription factor activity
EA719_016550	COG4221	oxidoreductase activity
EA719_016555	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EA719_016565	COG0534	Mate efflux family protein
EA719_016580	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EA719_016620	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EA719_016625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EA719_016640	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EA719_016650	COG0644	oxidoreductase
EA719_016650	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EA719_016655	COG0425	Belongs to the sulfur carrier protein TusA family
EA719_016660	COG4535	Mg2 and Co2 transporter CorC
EA719_016670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EA719_016690	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EA719_016695	COG0475	glutathione-regulated potassium exporter activity
EA719_016695	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EA719_016700	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EA719_016710	COG0484	heat shock protein binding
EA719_016715	COG0789	Transcriptional regulator
EA719_016720	COG0598	Magnesium transport protein CorA
EA719_016740	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EA719_016745	COG1074	ATP-dependent DNA helicase activity
EA719_016750	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EA719_016770	COG2226	methyltransferase
EA719_016785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EA719_016790	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EA719_016805	COG2111	Na H antiporter
EA719_016805	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EA719_016810	COG1006	Multisubunit Na H antiporter MnhC subunit
EA719_016815	COG0651	ATP synthesis coupled electron transport
EA719_016825	COG2212	antiporter activity
EA719_016845	COG0195	Participates in both transcription termination and antitermination
EA719_016895	COG0237	dephospho-CoA kinase activity
EA719_016905	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EA719_016920	COG0497	DNA recombination
EA719_016930	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EA719_016960	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EA719_016960	COG2169	Transcriptional regulator
EA719_016965	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EA719_017035	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EA719_017050	COG0326	Molecular chaperone. Has ATPase activity
EA719_017065	COG2056	Na+-H+ antiporter family
EA719_017070	COG0596	Alpha beta hydrolase
EA719_017165	COG0546	phosphoglycolate phosphatase activity
EA719_017170	COG1716	ATPase activity
EA719_017215	COG0181	hydroxymethylbilane synthase activity
EA719_017225	COG3275	phosphorelay sensor kinase activity
EA719_017245	COG1538	Outer membrane efflux protein
EA719_017250	COG0697	spore germination
EA719_017275	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EA719_017280	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EA719_017285	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EA719_017290	COG0772	Belongs to the SEDS family
EA719_017315	COG4974	Belongs to the 'phage' integrase family
EA719_017320	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EA719_017330	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EA719_017340	COG2197	response regulator
EA719_017355	COG0793	Belongs to the peptidase S41A family
EA719_017360	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EA719_017365	COG0795	lipopolysaccharide-transporting ATPase activity
EA719_017405	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EA719_017405	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EA719_017415	COG0004	ammonium transporteR
EA719_017420	COG0347	Belongs to the P(II) protein family
EA719_017430	COG0606	chelatase, subunit chli
EA719_017485	COG0659	secondary active sulfate transmembrane transporter activity
EA719_017490	COG0589	response to stress
EA719_017530	COG0606	chelatase, subunit chli
EA719_017535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EA719_017545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EA719_017560	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EA719_017575	COG0318	PFAM AMP-dependent synthetase and ligase
EA719_017585	COG0477	Major facilitator Superfamily
EA719_017590	COG2860	membrane
EA719_017600	COG1253	flavin adenine dinucleotide binding
EA719_017620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EA719_017655	COG0655	NAD(P)H dehydrogenase (quinone) activity
EA719_017665	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EA719_017700	COG1309	transcriptional regulator
EA719_017735	COG0758	DNA mediated transformation
EA719_017745	COG0697	spore germination
EA719_017750	COG1309	transcriptional regulator
EA719_017765	COG0386	Belongs to the glutathione peroxidase family
EA719_017830	COG1121	(ABC) transporter
EA719_017835	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EA719_017840	COG1280	lysine exporter protein (LysE YggA)
EA719_017845	COG2837	iron assimilation
EA719_017855	COG0281	malic enzyme
EA719_017900	COG0519	Catalyzes the synthesis of GMP from XMP
EA719_017900	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EA719_017905	COG4399	Belongs to the UPF0754 family
EA719_017910	COG2259	Doxx family
EA719_017915	COG0586	Pfam SNARE associated Golgi protein
EA719_017930	COG1192	Involved in chromosome partitioning
EA719_017940	COG0271	Belongs to the BolA IbaG family
EA719_017960	COG2267	carboxylic ester hydrolase activity
EA719_017980	COG3321	synthase
EA719_017980	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EA719_017980	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EA719_017980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EA719_017985	COG1960	acyl-CoA dehydrogenase activity
EA719_018005	COG3916	Acyl-homoserine-lactone synthase
EA719_018010	COG0477	Major facilitator Superfamily
EA719_018015	COG1024	Enoyl-CoA hydratase
EA719_018020	COG1024	Enoyl-CoA hydratase
EA719_018025	COG1960	acyl-CoA dehydrogenase activity
EA719_018030	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EA719_018050	COG1113	amino acid transport
EA719_018055	COG1113	amino acid transport
EA719_018060	COG0251	oxidation-reduction process
EA719_018075	COG1522	sequence-specific DNA binding
EA719_018100	COG0564	pseudouridine synthase activity
EA719_018165	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EA719_018180	COG1802	Transcriptional regulator
EA719_018190	COG1448	Aminotransferase
EA719_018195	COG0277	FAD linked oxidase domain protein
EA719_018205	COG2186	Transcriptional regulator
EA719_018215	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EA719_018220	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EA719_018235	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EA719_018240	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EA719_018245	COG1216	Glycosyl transferase, family 2
EA719_018275	COG2089	acid synthase
EA719_018290	COG1083	cytidylyl-transferase
EA719_018295	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EA719_018300	COG1086	Polysaccharide biosynthesis protein
EA719_018305	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EA719_018310	COG1596	polysaccharide export
EA719_018335	COG0728	peptidoglycan biosynthetic process
EA719_018340	COG3023	N-Acetylmuramoyl-L-alanine amidase
EA719_018395	COG0546	phosphoglycolate phosphatase activity
EA719_018400	COG1028	Short-chain dehydrogenase reductase Sdr
EA719_018420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EA719_018425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EA719_018430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EA719_018435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EA719_018440	COG1116	anion transmembrane transporter activity
EA719_018445	COG1309	transcriptional regulator
EA719_018450	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EA719_018460	COG0196	riboflavin kinase activity
EA719_018465	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EA719_018475	COG1047	Peptidyl-prolyl cis-trans
EA719_018515	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EA719_018570	COG2951	lytic endotransglycosylase activity
EA719_018575	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EA719_018595	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EA719_018605	COG0671	phosphoesterase, PA-phosphatase related
EA719_018610	COG0861	Integral membrane protein TerC family
EA719_018620	COG0754	glutathionylspermidine amidase activity
EA719_018630	COG0402	S-adenosylhomocysteine deaminase activity
EA719_018645	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EA719_018650	COG1230	cation diffusion facilitator family transporter
EA719_018665	COG0706	membrane insertase activity
EA719_018680	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EA719_018690	COG0194	GDP metabolic process
EA719_018715	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EA719_018760	COG0587	DNA-directed DNA polymerase activity
EA719_018775	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EA719_018775	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EA719_018830	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EA719_018830	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EA719_018835	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EA719_018870	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EA719_018915	COG2130	NADP-dependent
EA719_018925	COG1309	transcriptional regulator
EA719_018935	COG1902	pentaerythritol trinitrate reductase activity
EA719_018945	COG1979	alcohol dehydrogenase
EA719_018955	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EA719_018980	COG1063	alcohol dehydrogenase
EA719_019050	COG1388	LysM domain
EA719_019065	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EA719_019085	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EA719_019265	COG0358	DNA primase activity
EA719_019330	COG0589	response to stress
EA719_019335	COG0659	secondary active sulfate transmembrane transporter activity
EA719_019350	COG1061	Type III restriction enzyme res subunit