locus-tag	class	description
EA743_000010	COG0592	DNA-directed DNA polymerase activity
EA743_000020	COG0187	DNA topoisomerase II activity
EA743_000030	COG0586	Pfam SNARE associated Golgi protein
EA743_000035	COG0488	(ABC) transporter
EA743_000060	COG0596	Alpha beta hydrolase
EA743_000065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EA743_000070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EA743_000115	COG0733	neurotransmitter:sodium symporter activity
EA743_000150	COG0583	DNA-binding transcription factor activity
EA743_000155	COG2233	PERMEase
EA743_000170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA743_000205	COG2814	Major facilitator Superfamily
EA743_000210	COG0656	L-ascorbic acid biosynthetic process
EA743_000215	COG0583	DNA-binding transcription factor activity
EA743_000230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EA743_000235	COG1064	alcohol dehydrogenase
EA743_000240	COG2818	Glycosylase
EA743_000255	COG1194	a g-specific adenine glycosylase
EA743_000275	COG2983	Belongs to the UPF0260 family
EA743_000280	COG2133	pyrroloquinoline quinone binding
EA743_000285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EA743_000290	COG2116	formate transmembrane transporter activity
EA743_000310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EA743_000315	COG1335	isochorismatase
EA743_000320	COG0385	Bile acid
EA743_000330	COG1683	Conserved Protein
EA743_000350	COG0625	glutathione transferase activity
EA743_000360	COG1113	amino acid transport
EA743_000370	COG0523	cobalamin synthesis protein
EA743_000380	COG2188	Transcriptional regulator
EA743_000400	COG1126	abc transporter atp-binding protein
EA743_000415	COG3316	Transposase and inactivated derivatives
EA743_000435	COG3316	Transposase and inactivated derivatives
EA743_000470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EA743_000495	COG2963	transposase activity
EA743_000505	COG4372	Transposase
EA743_000535	COG2963	transposase activity
EA743_000565	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EA743_000600	COG3316	Transposase and inactivated derivatives
EA743_000630	COG0010	Belongs to the arginase family
EA743_000645	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EA743_000650	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EA743_000660	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EA743_000665	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EA743_000755	COG0534	Mate efflux family protein
EA743_000760	COG0436	Aminotransferase
EA743_000765	COG2733	membrane
EA743_000780	COG2918	glutathione biosynthetic process
EA743_000790	COG3501	Rhs element vgr protein
EA743_000795	COG3179	chitinase
EA743_000810	COG3150	esterase
EA743_000820	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
EA743_000830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EA743_000840	COG2233	PERMEase
EA743_000845	COG2351	hydroxyisourate hydrolase activity
EA743_000880	COG3706	GGDEF domain
EA743_000895	COG1393	Belongs to the ArsC family
EA743_000900	COG0708	Exodeoxyribonuclease III
EA743_000925	COG0189	ligase activity
EA743_000945	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EA743_000955	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EA743_000970	COG4942	peptidase
EA743_000980	COG0508	dehydrogenase complex catalyzes the overall conversion of
EA743_000990	COG2119	membrane
EA743_000995	COG4774	siderophore transport
EA743_001000	COG0426	domain, Protein
EA743_001000	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EA743_001025	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EA743_001050	COG1902	pentaerythritol trinitrate reductase activity
EA743_001055	COG1519	Transferase
EA743_001060	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EA743_001065	COG0668	transmembrane transport
EA743_001075	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EA743_001080	COG1335	isochorismatase
EA743_001085	COG1522	sequence-specific DNA binding
EA743_001110	COG2205	protein histidine kinase activity
EA743_001110	COG0784	Response regulator, receiver
EA743_001110	COG2198	Histidine kinase
EA743_001115	COG3162	membrane
EA743_001120	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EA743_001130	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EA743_001140	COG3706	GGDEF domain
EA743_001150	COG1309	transcriptional regulator
EA743_001170	COG0351	phosphomethylpyrimidine kinase
EA743_001170	COG0352	thiamine-phosphate diphosphorylase activity
EA743_001170	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EA743_001180	COG2814	Major facilitator Superfamily
EA743_001195	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EA743_001205	COG1113	amino acid transport
EA743_001215	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EA743_001220	COG1012	belongs to the aldehyde dehydrogenase family
EA743_001230	COG1335	isochorismatase
EA743_001260	COG2814	Major facilitator Superfamily
EA743_001265	COG0583	DNA-binding transcription factor activity
EA743_001285	COG0667	Aldo Keto reductase
EA743_001320	COG1733	regulation of RNA biosynthetic process
EA743_001330	COG2249	NAD(P)H dehydrogenase (quinone) activity
EA743_001390	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EA743_001415	COG1132	(ABC) transporter
EA743_001435	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EA743_001465	COG0427	acetyl-CoA hydrolase
EA743_001480	COG0745	RESPONSE REGULATOR receiver
EA743_001490	COG0659	secondary active sulfate transmembrane transporter activity
EA743_001495	COG4221	oxidoreductase activity
EA743_001505	COG0488	(ABC) transporter
EA743_001570	COG0833	amino acid
EA743_001615	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EA743_001620	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EA743_001635	COG2226	methyltransferase
EA743_001685	COG0067	glutamate synthase
EA743_001685	COG0069	glutamate synthase activity
EA743_001685	COG0070	glutamate synthase
EA743_001690	COG0493	'glutamate synthase
EA743_001700	COG1704	LemA family
EA743_001705	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EA743_001725	COG3307	-O-antigen
EA743_001745	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EA743_001760	COG0194	GDP metabolic process
EA743_001810	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EA743_001830	COG5380	lipid catabolic process
EA743_001835	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EA743_001860	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EA743_001865	COG0277	FAD linked oxidase domain protein
EA743_001880	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EA743_001885	COG2249	NAD(P)H dehydrogenase (quinone) activity
EA743_001900	COG1289	transmembrane transporter activity
EA743_001910	COG0628	permease
EA743_001915	COG1192	Involved in chromosome partitioning
EA743_001945	COG0833	amino acid
EA743_001955	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EA743_001960	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EA743_001970	COG1012	belongs to the aldehyde dehydrogenase family
EA743_002010	COG0583	DNA-binding transcription factor activity
EA743_002060	COG0517	IMP dehydrogenase activity
EA743_002065	COG1983	PspC domain protein
EA743_002075	COG1960	acyl-CoA dehydrogenase activity
EA743_002090	COG0408	coproporphyrinogen oxidase activity
EA743_002110	COG0513	Belongs to the DEAD box helicase family
EA743_002120	COG1127	ABC transporter
EA743_002125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EA743_002135	COG2854	intermembrane phospholipid transfer
EA743_002145	COG0598	Magnesium transport protein CorA
EA743_002155	COG0494	nUDIX hydrolase
EA743_002160	COG1040	competence protein
EA743_002165	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EA743_002185	COG1946	Acyl-CoA thioesterase
EA743_002190	COG1301	dicarboxylic acid transport
EA743_002205	COG1959	2 iron, 2 sulfur cluster binding
EA743_002210	COG1017	nitric oxide dioxygenase activity
EA743_002210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EA743_002220	COG0433	COG0433 Predicted ATPase
EA743_002225	COG0626	cystathionine gamma-synthase activity
EA743_002345	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EA743_002355	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EA743_002380	COG1960	acyl-CoA dehydrogenase activity
EA743_002385	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EA743_002415	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EA743_002420	COG0339	signal peptide processing
EA743_002425	COG0557	exoribonuclease II activity
EA743_002475	COG0179	Fumarylacetoacetate (FAA) hydrolase
EA743_002480	COG2169	Transcriptional regulator
EA743_002485	COG0697	spore germination
EA743_002490	COG1295	ribonuclease BN
EA743_002525	COG1702	phosphate starvation-inducible protein PhoH
EA743_002535	COG0741	lytic transglycosylase activity
EA743_002535	COG1196	nuclear chromosome segregation
EA743_002535	COG0739	heme binding
EA743_002565	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EA743_002570	COG1183	phosphatidylcholine synthase activity
EA743_002615	COG1960	acyl-CoA dehydrogenase activity
EA743_002620	COG1309	transcriptional regulator
EA743_002635	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EA743_002640	COG1960	acyl-CoA dehydrogenase activity
EA743_002660	COG2969	positive regulation of protein catabolic process
EA743_002670	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EA743_002680	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EA743_002685	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EA743_002690	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EA743_002710	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EA743_002720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EA743_002725	COG1408	metallophosphoesterase
EA743_002735	COG2199	diguanylate cyclase activity
EA743_002780	COG3453	Protein conserved in bacteria
EA743_002780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EA743_002795	COG1607	acyl-coa hydrolase
EA743_002825	COG2350	Protein conserved in bacteria
EA743_002835	COG0613	PHP domain protein
EA743_002840	COG3781	membrane
EA743_002850	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EA743_002855	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EA743_002865	COG1862	Preprotein translocase
EA743_002895	COG2205	protein histidine kinase activity
EA743_002900	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EA743_002920	COG0726	polysaccharide deacetylase
EA743_002925	COG0463	Glycosyl transferase, family 2
EA743_002930	COG0438	transferase activity, transferring glycosyl groups
EA743_002995	COG1960	acyl-CoA dehydrogenase activity
EA743_003000	COG1960	acyl-CoA dehydrogenase activity
EA743_003010	COG2205	protein histidine kinase activity
EA743_003015	COG0745	RESPONSE REGULATOR receiver
EA743_003020	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EA743_003040	COG2096	Adenosyltransferase
EA743_003055	COG0133	tryptophan synthase activity
EA743_003090	COG0285	dihydrofolate synthase activity
EA743_003110	COG0450	alkyl hydroperoxide reductase
EA743_003125	COG0477	Major facilitator Superfamily
EA743_003130	COG1272	protein, Hemolysin III
EA743_003160	COG0183	Belongs to the thiolase family
EA743_003165	COG2207	Transcriptional regulator
EA743_003185	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EA743_003205	COG0183	Belongs to the thiolase family
EA743_003215	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EA743_003215	COG2885	chlorophyll binding
EA743_003225	COG1690	Belongs to the RtcB family
EA743_003230	COG0833	amino acid
EA743_003240	COG2233	PERMEase
EA743_003270	COG2094	Belongs to the DNA glycosylase MPG family
EA743_003275	COG4772	TonB-dependent receptor
EA743_003280	COG1902	pentaerythritol trinitrate reductase activity
EA743_003285	COG0679	Auxin Efflux Carrier
EA743_003295	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EA743_003300	COG0354	folic acid binding
EA743_003310	COG3189	MarR family transcriptional regulator
EA743_003315	COG2824	Alkylphosphonate utilization operon protein PhnA
EA743_003320	COG3422	double-strand break repair
EA743_003360	COG0840	transmembrane signaling receptor activity
EA743_003380	COG5510	response to toxic substance
EA743_003390	COG2832	Protein of unknown function (DUF454)
EA743_003395	COG1376	ErfK ybiS ycfS ynhG family protein
EA743_003445	COG1289	transmembrane transporter activity
EA743_003450	COG2814	Major facilitator Superfamily
EA743_003470	COG1115	amino acid carrier protein
EA743_003475	COG1752	Esterase of the alpha-beta hydrolase superfamily
EA743_003480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EA743_003485	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EA743_003510	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EA743_003520	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EA743_003525	COG1077	Cell shape determining protein MreB Mrl
EA743_003530	COG1792	Involved in formation and maintenance of cell shape
EA743_003535	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EA743_003540	COG0424	maF-like protein
EA743_003545	COG1530	ribonuclease E activity
EA743_003555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EA743_003575	COG2249	NAD(P)H dehydrogenase (quinone) activity
EA743_003600	COG2207	Transcriptional regulator
EA743_003650	COG1113	amino acid transport
EA743_003655	COG2828	Protein conserved in bacteria
EA743_003660	COG0142	geranyltranstransferase activity
EA743_003665	COG2315	Protein conserved in bacteria
EA743_003680	COG1752	Esterase of the alpha-beta hydrolase superfamily
EA743_003695	COG2963	transposase activity
EA743_003705	COG4372	Transposase
EA743_003720	COG4372	Transposase
EA743_003730	COG2963	transposase activity
EA743_003740	COG0745	RESPONSE REGULATOR receiver
EA743_003745	COG0642	Histidine kinase
EA743_003755	COG0004	ammonium transporteR
EA743_003765	COG0583	DNA-binding transcription factor activity
EA743_003780	COG2226	methyltransferase
EA743_003785	COG0525	valine-tRNA ligase activity
EA743_003795	COG1028	Short-chain dehydrogenase reductase Sdr
EA743_003805	COG0393	Putative heavy-metal-binding
EA743_003810	COG0393	Putative heavy-metal-binding
EA743_003815	COG1538	Outer membrane efflux protein
EA743_003825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA743_003830	COG0671	phosphoesterase, PA-phosphatase related
EA743_003860	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EA743_003875	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EA743_003875	COG1648	precorrin-2 dehydrogenase activity
EA743_003880	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EA743_003885	COG1733	regulation of RNA biosynthetic process
EA743_003895	COG0531	amino acid
EA743_003910	COG0321	lipoyl(octanoyl) transferase activity
EA743_003915	COG2921	Belongs to the UPF0250 family
EA743_003955	COG2009	succinate dehydrogenase
EA743_003960	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EA743_003965	COG1053	succinate dehydrogenase
EA743_003970	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EA743_003995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EA743_004015	COG2354	Protein conserved in bacteria
EA743_004020	COG2321	neutral zinc metallopeptidase
EA743_004040	COG2843	Capsule synthesis protein
EA743_004055	COG0589	response to stress
EA743_004075	COG0505	Belongs to the CarA family
EA743_004100	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EA743_004105	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EA743_004155	COG0477	Major facilitator Superfamily
EA743_004160	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EA743_004180	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EA743_004205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EA743_004210	COG0584	glycerophosphoryl diester phosphodiesterase
EA743_004230	COG0741	lytic transglycosylase activity
EA743_004255	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EA743_004280	COG3811	Belongs to the UPF0386 family
EA743_004305	COG0778	Nitroreductase
EA743_004320	COG1929	Belongs to the glycerate kinase type-1 family
EA743_004325	COG0243	molybdopterin cofactor binding
EA743_004330	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EA743_004335	COG3339	Conserved Protein
EA743_004345	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EA743_004360	COG1113	amino acid transport
EA743_004370	COG0019	diaminopimelate decarboxylase activity
EA743_004380	COG1280	lysine exporter protein (LysE YggA)
EA743_004385	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EA743_004415	COG0463	Glycosyl transferase, family 2
EA743_004435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA743_004465	COG4591	ABC-type transport system involved in lipoprotein release permease component
EA743_004470	COG1136	(ABC) transporter
EA743_004475	COG0658	competence protein
EA743_004475	COG2333	competence protein COMEC
EA743_004485	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EA743_004485	COG0616	signal peptide processing
EA743_004490	COG0596	Alpha beta hydrolase
EA743_004495	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EA743_004505	COG0628	permease
EA743_004525	COG4372	Transposase
EA743_004535	COG2963	transposase activity
EA743_004545	COG4372	Transposase
EA743_004555	COG2963	transposase activity
EA743_004580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EA743_004600	COG0823	Involved in the tonB-independent uptake of proteins
EA743_004620	COG0824	Thioesterase
EA743_004625	COG1473	amidohydrolase
EA743_004645	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EA743_004645	COG0047	phosphoribosylformylglycinamidine synthase activity
EA743_004650	COG2814	Major facilitator Superfamily
EA743_004655	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EA743_004660	COG1024	Enoyl-CoA hydratase
EA743_004665	COG1051	belongs to the nudix hydrolase family
EA743_004665	COG1056	cytidyltransferase-related domain
EA743_004675	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EA743_004690	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EA743_004705	COG4625	pathogenesis
EA743_004710	COG0583	DNA-binding transcription factor activity
EA743_004715	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EA743_004720	COG4208	sulfate ABC transporter
EA743_004725	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EA743_004735	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EA743_004740	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EA743_004745	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EA743_004765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EA743_004780	COG0681	Belongs to the peptidase S26 family
EA743_004795	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EA743_004805	COG1381	Involved in DNA repair and RecF pathway recombination
EA743_004810	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EA743_004820	COG4221	oxidoreductase activity
EA743_004850	COG0443	Heat shock 70 kDa protein
EA743_004880	COG0556	nucleotide-excision repair
EA743_004935	COG2070	2-Nitropropane dioxygenase
EA743_004965	COG1215	transferase activity, transferring glycosyl groups
EA743_004980	COG0415	Belongs to the DNA photolyase family
EA743_004990	COG1252	NADH dehydrogenase
EA743_004995	COG1686	Belongs to the peptidase S11 family
EA743_005010	COG1187	pseudouridine synthase activity
EA743_005035	COG0477	Major facilitator Superfamily
EA743_005040	COG0583	DNA-binding transcription factor activity
EA743_005055	COG0612	Peptidase, M16
EA743_005080	COG4372	Transposase
EA743_005090	COG2963	transposase activity
EA743_005100	COG0352	thiamine-phosphate diphosphorylase activity
EA743_005135	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EA743_005145	COG2249	NAD(P)H dehydrogenase (quinone) activity
EA743_005160	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EA743_005165	COG0076	glutamate decarboxylase activity
EA743_005175	COG1522	sequence-specific DNA binding
EA743_005180	COG3961	Belongs to the TPP enzyme family
EA743_005185	COG1113	amino acid transport
EA743_005190	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EA743_005195	COG0573	inorganic phosphate transmembrane transporter activity
EA743_005205	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EA743_005210	COG0616	signal peptide processing
EA743_005245	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EA743_005250	COG1686	Belongs to the peptidase S11 family
EA743_005275	COG0583	DNA-binding transcription factor activity
EA743_005280	COG1067	ATP-dependent peptidase activity
EA743_005305	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EA743_005325	COG1966	Carbon starvation protein
EA743_005330	COG2879	small protein
EA743_005375	COG1335	isochorismatase
EA743_005380	COG0583	DNA-binding transcription factor activity
EA743_005395	COG0596	Alpha beta hydrolase
EA743_005405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EA743_005415	COG0583	DNA-binding transcription factor activity
EA743_005420	COG1902	pentaerythritol trinitrate reductase activity
EA743_005425	COG0006	proline dipeptidase activity
EA743_005430	COG0477	Major facilitator Superfamily
EA743_005450	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EA743_005455	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EA743_005455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EA743_005490	COG2814	Major facilitator Superfamily
EA743_005495	COG4948	Mandelate Racemase Muconate Lactonizing
EA743_005505	COG2963	transposase activity
EA743_005515	COG4372	Transposase
EA743_005525	COG1309	transcriptional regulator
EA743_005540	COG1741	Belongs to the pirin family
EA743_005550	COG2964	Protein conserved in bacteria
EA743_005565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EA743_005570	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EA743_005575	COG4605	iron ion homeostasis
EA743_005580	COG4604	ABC transporter, ATP-binding protein
EA743_005585	COG4607	ABC-type enterochelin transport system periplasmic component
EA743_005590	COG4774	siderophore transport
EA743_005600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EA743_005605	COG1021	2,3-dihydroxybenzoate-AMP ligase
EA743_005610	COG3433	isochorismatase activity
EA743_005610	COG1535	isochorismatase
EA743_005625	COG1132	(ABC) transporter
EA743_005635	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EA743_005660	COG3739	integral membrane protein
EA743_005695	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EA743_005725	COG0308	aminopeptidase N
EA743_005730	COG0512	Glutamine amidotransferase of anthranilate synthase
EA743_005885	COG3617	BRO family, N-terminal domain
EA743_006115	COG2194	sulfuric ester hydrolase activity
EA743_006145	COG0006	proline dipeptidase activity
EA743_006150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EA743_006155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EA743_006175	COG1279	arginine transmembrane transporter activity
EA743_006180	COG0583	DNA-binding transcription factor activity
EA743_006220	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EA743_006225	COG1388	LysM domain
EA743_006225	COG0741	lytic transglycosylase activity
EA743_006225	COG0741	lytic transglycosylase activity
EA743_006225	COG1388	LysM domain
EA743_006235	COG4174	ABC transporter (Permease)
EA743_006240	COG4239	(ABC) transporter, permease
EA743_006245	COG4172	Belongs to the ABC transporter superfamily
EA743_006265	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EA743_006275	COG5001	Diguanylate cyclase
EA743_006275	COG3706	GGDEF domain
EA743_006275	COG2203	Gaf domain
EA743_006275	COG4251	negative regulation of phosphorylation
EA743_006285	COG1902	pentaerythritol trinitrate reductase activity
EA743_006285	COG0446	pyridine nucleotide-disulphide oxidoreductase
EA743_006300	COG4269	membrane
EA743_006340	COG1113	amino acid transport
EA743_006350	COG0531	amino acid
EA743_006370	COG1012	belongs to the aldehyde dehydrogenase family
EA743_006390	COG1113	amino acid transport
EA743_006405	COG0697	spore germination
EA743_006410	COG2721	sulfolactate sulfo-lyase activity
EA743_006415	COG2271	Major facilitator Superfamily
EA743_006420	COG4948	Mandelate Racemase Muconate Lactonizing
EA743_006430	COG1012	belongs to the aldehyde dehydrogenase family
EA743_006435	COG2186	Transcriptional regulator
EA743_006460	COG1960	acyl-CoA dehydrogenase activity
EA743_006470	COG1012	belongs to the aldehyde dehydrogenase family
EA743_006475	COG1024	Enoyl-CoA hydratase
EA743_006480	COG2814	Major facilitator Superfamily
EA743_006495	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EA743_006510	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EA743_006555	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EA743_006560	COG2072	flavoprotein involved in K transport
EA743_006565	COG0300	oxidoreductase activity
EA743_006575	COG1309	transcriptional regulator
EA743_006580	COG1741	Belongs to the pirin family
EA743_006595	COG2072	flavoprotein involved in K transport
EA743_006605	COG2252	PERMEase
EA743_006610	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EA743_006615	COG3038	cytochrome b561
EA743_006625	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EA743_006690	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EA743_006695	COG4197	protein conserved in bacteria, prophage-related
EA743_006845	COG0582	viral genome integration into host DNA
EA743_006855	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EA743_006870	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EA743_006885	COG0667	Aldo Keto reductase
EA743_006895	COG1765	OsmC-like protein
EA743_006945	COG2885	chlorophyll binding
EA743_006955	COG0625	glutathione transferase activity
EA743_006960	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EA743_006980	COG3634	alkyl hydroperoxide reductase activity
EA743_006990	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EA743_007000	COG0450	alkyl hydroperoxide reductase
EA743_007005	COG1643	Atp-dependent helicase
EA743_007020	COG2814	Major facilitator Superfamily
EA743_007025	COG3135	benzoate transporter
EA743_007030	COG1028	Short-chain dehydrogenase reductase Sdr
EA743_007035	COG0543	2 iron, 2 sulfur cluster binding
EA743_007035	COG0633	Ferredoxin
EA743_007040	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EA743_007045	COG4638	Rieske (2fe-2S)
EA743_007050	COG0583	DNA-binding transcription factor activity
EA743_007105	COG1570	exodeoxyribonuclease VII activity
EA743_007140	COG1280	lysine exporter protein (LysE YggA)
EA743_007145	COG1278	Cold shock
EA743_007185	COG2814	Major facilitator Superfamily
EA743_007190	COG1733	regulation of RNA biosynthetic process
EA743_007230	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EA743_007240	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EA743_007245	COG1137	ATPase activity
EA743_007250	COG1538	Outer membrane efflux protein
EA743_007260	COG2963	transposase activity
EA743_007270	COG4372	Transposase
EA743_007310	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EA743_007325	COG1522	sequence-specific DNA binding
EA743_007330	COG5006	permease, DMT superfamily
EA743_007340	COG1560	Kdo2-lipid A biosynthetic process
EA743_007355	COG2814	Major facilitator Superfamily
EA743_007375	COG1250	3-hydroxyacyl-CoA dehydrogenase
EA743_007410	COG0583	DNA-binding transcription factor activity
EA743_007415	COG1914	H( )-stimulated, divalent metal cation uptake system
EA743_007435	COG4770	biotin carboxylase activity
EA743_007440	COG0038	chloride channel
EA743_007445	COG2831	hemolysin activation secretion protein
EA743_007450	COG3210	domain, Protein
EA743_007480	COG1063	alcohol dehydrogenase
EA743_007495	COG0439	Biotin carboxylase
EA743_007500	COG2249	NAD(P)H dehydrogenase (quinone) activity
EA743_007505	COG1733	regulation of RNA biosynthetic process
EA743_007520	COG0864	Transcriptional regulator
EA743_007530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EA743_007535	COG1116	anion transmembrane transporter activity
EA743_007605	COG2885	chlorophyll binding
EA743_007605	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EA743_007645	COG0583	DNA-binding transcription factor activity
EA743_007655	COG0590	tRNA wobble adenosine to inosine editing
EA743_007660	COG2807	transmembrane transport
EA743_007675	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EA743_007685	COG0789	Transcriptional regulator
EA743_007700	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EA743_007720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EA743_007745	COG1012	belongs to the aldehyde dehydrogenase family
EA743_007750	COG0531	amino acid
EA743_007755	COG1760	l-serine dehydratase
EA743_007760	COG2030	dehydratase
EA743_007760	COG1012	belongs to the aldehyde dehydrogenase family
EA743_007765	COG3396	Phenylacetate-CoA oxygenase
EA743_007770	COG3460	Phenylacetate-CoA oxygenase
EA743_007775	COG3396	Phenylacetate-CoA oxygenase
EA743_007780	COG2151	metal-sulfur cluster biosynthetic enzyme
EA743_007785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EA743_007790	COG1024	Enoyl-CoA hydratase
EA743_007795	COG1024	Enoyl-CoA hydratase
EA743_007800	COG1250	3-hydroxyacyl-CoA dehydrogenase
EA743_007805	COG0183	Belongs to the thiolase family
EA743_007810	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EA743_007815	COG3327	negative regulation of DNA-templated transcription, initiation
EA743_007825	COG2050	protein possibly involved in aromatic compounds catabolism
EA743_007860	COG0753	catalase activity
EA743_007865	COG3038	cytochrome b561
EA743_007885	COG2267	carboxylic ester hydrolase activity
EA743_007890	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EA743_007895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EA743_007900	COG1012	belongs to the aldehyde dehydrogenase family
EA743_007910	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EA743_007920	COG1012	belongs to the aldehyde dehydrogenase family
EA743_007925	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EA743_007930	COG0583	DNA-binding transcription factor activity
EA743_007940	COG1414	Transcriptional regulator
EA743_007945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EA743_007955	COG1840	ABC-type Fe3 transport system, periplasmic component
EA743_007960	COG3842	ATPase activity
EA743_007975	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EA743_007980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EA743_007985	COG2814	Major facilitator Superfamily
EA743_007990	COG1960	acyl-CoA dehydrogenase activity
EA743_007995	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EA743_008005	COG1024	Enoyl-CoA hydratase
EA743_008015	COG2814	Major facilitator Superfamily
EA743_008025	COG0183	Belongs to the thiolase family
EA743_008030	COG1250	3-hydroxyacyl-CoA dehydrogenase
EA743_008035	COG1028	Short-chain dehydrogenase reductase Sdr
EA743_008040	COG1024	Enoyl-CoA hydratase
EA743_008045	COG1960	acyl-CoA dehydrogenase activity
EA743_008050	COG2814	Major facilitator Superfamily
EA743_008055	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EA743_008060	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EA743_008070	COG2814	Major facilitator Superfamily
EA743_008080	COG1960	acyl-CoA dehydrogenase activity
EA743_008095	COG0583	DNA-binding transcription factor activity
EA743_008110	COG1024	Enoyl-CoA hydratase
EA743_008115	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EA743_008120	COG1960	acyl-CoA dehydrogenase activity
EA743_008125	COG1309	transcriptional regulator
EA743_008130	COG0318	PFAM AMP-dependent synthetase and ligase
EA743_008150	COG0583	DNA-binding transcription factor activity
EA743_008195	COG1028	Short-chain dehydrogenase reductase Sdr
EA743_008215	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EA743_008235	COG0784	Response regulator, receiver
EA743_008235	COG2205	protein histidine kinase activity
EA743_008255	COG0765	amino acid transport
EA743_008260	COG0765	amino acid transport
EA743_008265	COG1126	abc transporter atp-binding protein
EA743_008270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EA743_008275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EA743_008290	COG1280	lysine exporter protein (LysE YggA)
EA743_008295	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EA743_008300	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EA743_008305	COG1045	serine acetyltransferase
EA743_008320	COG0583	DNA-binding transcription factor activity
EA743_008325	COG0625	glutathione transferase activity
EA743_008330	COG0625	glutathione transferase activity
EA743_008335	COG0583	DNA-binding transcription factor activity
EA743_008345	COG1346	cytolysis
EA743_008365	COG2814	Major facilitator Superfamily
EA743_008375	COG0583	DNA-binding transcription factor activity
EA743_008385	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
EA743_008390	COG3052	prosthetic group binding
EA743_008410	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EA743_008430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EA743_008440	COG1294	oxidase, subunit
EA743_008445	COG1271	oxidase subunit
EA743_008470	COG0477	Major facilitator Superfamily
EA743_008490	COG4521	taurine ABC transporter
EA743_008495	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EA743_008500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EA743_008505	COG2175	clavaminate synthase activity
EA743_008515	COG1953	Uracil, thiamine, allantoin
EA743_008525	COG0583	DNA-binding transcription factor activity
EA743_008535	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EA743_008550	COG0640	Transcriptional regulator
EA743_008555	COG0798	PFAM Bile acid sodium symporter
EA743_008560	COG0583	DNA-binding transcription factor activity
EA743_008575	COG3634	alkyl hydroperoxide reductase activity
EA743_008615	COG0436	Aminotransferase
EA743_008625	COG0386	Belongs to the glutathione peroxidase family
EA743_008665	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EA743_008690	COG0012	GTP binding
EA743_008695	COG2011	ABC-type metal ion transport system permease component
EA743_008700	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EA743_008710	COG1464	Belongs to the NlpA lipoprotein family
EA743_008740	COG0765	amino acid transport
EA743_008745	COG0765	amino acid transport
EA743_008750	COG1126	abc transporter atp-binding protein
EA743_008760	COG1522	sequence-specific DNA binding
EA743_008775	COG1309	transcriptional regulator
EA743_008795	COG0583	DNA-binding transcription factor activity
EA743_008805	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EA743_008815	COG0697	spore germination
EA743_008845	COG3121	Chaperone
EA743_008850	COG3539	Fimbrial protein
EA743_008875	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EA743_008875	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EA743_008925	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EA743_008935	COG2353	YceI-like domain
EA743_008945	COG3698	Phosphodiester glycosidase
EA743_008960	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EA743_008965	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EA743_008965	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EA743_008965	COG0506	proline dehydrogenase activity
EA743_008975	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EA743_008980	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EA743_009000	COG1132	(ABC) transporter
EA743_009005	COG3122	Protein conserved in bacteria
EA743_009010	COG3619	membrane
EA743_009020	COG0640	Transcriptional regulator
EA743_009030	COG2850	peptidyl-arginine hydroxylation
EA743_009035	COG0424	maF-like protein
EA743_009055	COG0191	fructose-bisphosphate aldolase activity
EA743_009060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EA743_009075	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EA743_009085	COG1192	Involved in chromosome partitioning
EA743_009090	COG1475	DNA binding
EA743_009095	COG0811	peptide transport
EA743_009105	COG1132	(ABC) transporter
EA743_009110	COG1663	tetraacyldisaccharide 4'-kinase activity
EA743_009130	COG0084	hydrolase, TatD family'
EA743_009145	COG2165	general secretion pathway protein
EA743_009175	COG0590	tRNA wobble adenosine to inosine editing
EA743_009195	COG0776	regulation of translation
EA743_009225	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EA743_009230	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EA743_009280	COG0339	signal peptide processing
EA743_009290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EA743_009325	COG0702	epimerase
EA743_009330	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EA743_009350	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EA743_009380	COG0316	Belongs to the HesB IscA family
EA743_009385	COG0822	iron-sulfur transferase activity
EA743_009410	COG0776	regulation of translation
EA743_009415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EA743_009420	COG2207	Transcriptional regulator
EA743_009425	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EA743_009430	COG1960	acyl-CoA dehydrogenase activity
EA743_009435	COG1960	acyl-CoA dehydrogenase activity
EA743_009450	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EA743_009470	COG4264	IucA IucC family
EA743_009475	COG4264	IucA IucC family
EA743_009485	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EA743_009515	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EA743_009530	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EA743_009550	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EA743_009555	COG0730	response to heat
EA743_009575	COG4773	Receptor
EA743_009580	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EA743_009595	COG1131	(ABC) transporter
EA743_009600	COG0842	Transport permease protein
EA743_009605	COG0842	Transport permease protein
EA743_009625	COG2963	transposase activity
EA743_009635	COG4372	Transposase
EA743_009675	COG2226	methyltransferase
EA743_009700	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EA743_009735	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EA743_009745	COG0133	tryptophan synthase activity
EA743_009760	COG2963	transposase activity
EA743_009770	COG4372	Transposase
EA743_009775	COG3706	GGDEF domain
EA743_009790	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EA743_009795	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EA743_009800	COG0022	dehydrogenase e1 component
EA743_009805	COG0508	dehydrogenase complex catalyzes the overall conversion of
EA743_009810	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EA743_009820	COG1063	alcohol dehydrogenase
EA743_009825	COG3781	membrane
EA743_009835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EA743_009835	COG3453	Protein conserved in bacteria
EA743_009845	COG0730	response to heat
EA743_009860	COG3708	Transcriptional regulator
EA743_009860	COG2207	Transcriptional regulator
EA743_009865	COG1733	regulation of RNA biosynthetic process
EA743_009870	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EA743_009895	COG4521	taurine ABC transporter
EA743_009920	COG0477	Major facilitator Superfamily
EA743_009930	COG1027	Aspartate ammonia-lyase
EA743_009945	COG0583	DNA-binding transcription factor activity
EA743_009955	COG0583	DNA-binding transcription factor activity
EA743_009960	COG0183	Belongs to the thiolase family
EA743_009965	COG2031	fatty acid transporter
EA743_009980	COG0583	DNA-binding transcription factor activity
EA743_010000	COG1309	transcriptional regulator
EA743_010010	COG2610	gluconate transmembrane transporter activity
EA743_010015	COG1028	Short-chain dehydrogenase reductase Sdr
EA743_010020	COG2207	Transcriptional regulator
EA743_010030	COG0412	Dienelactone hydrolase
EA743_010035	COG1028	Short-chain dehydrogenase reductase Sdr
EA743_010045	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EA743_010060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EA743_010060	COG0543	2 iron, 2 sulfur cluster binding
EA743_010065	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EA743_010070	COG4638	Rieske (2fe-2S)
EA743_010080	COG0725	ABC transporter, periplasmic molybdate-binding protein
EA743_010085	COG4149	molybdate abc transporter
EA743_010090	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EA743_010095	COG1028	Short-chain dehydrogenase reductase Sdr
EA743_010100	COG3433	isochorismatase activity
EA743_010100	COG1535	isochorismatase
EA743_010170	COG2963	transposase activity
EA743_010180	COG4372	Transposase
EA743_010200	COG0753	catalase activity
EA743_010210	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EA743_010265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EA743_010270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA743_010275	COG0745	RESPONSE REGULATOR receiver
EA743_010285	COG2963	transposase activity
EA743_010295	COG4372	Transposase
EA743_010310	COG2207	Transcriptional regulator
EA743_010325	COG1028	Short-chain dehydrogenase reductase Sdr
EA743_010330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EA743_010335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EA743_010340	COG2851	Citrate transporter
EA743_010345	COG1414	Transcriptional regulator
EA743_010355	COG0583	DNA-binding transcription factor activity
EA743_010365	COG0477	Major facilitator Superfamily
EA743_010395	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EA743_010435	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EA743_010485	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EA743_010505	COG1120	ATPase activity
EA743_010520	COG1064	alcohol dehydrogenase
EA743_010535	COG2207	Transcriptional regulator
EA743_010540	COG2084	Dehydrogenase
EA743_010550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EA743_010555	COG0583	DNA-binding transcription factor activity
EA743_010565	COG0129	dihydroxy-acid dehydratase activity
EA743_010570	COG1012	belongs to the aldehyde dehydrogenase family
EA743_010585	COG1566	PFAM secretion protein HlyD family protein
EA743_010610	COG0583	DNA-binding transcription factor activity
EA743_010660	COG4191	Histidine kinase
EA743_010680	COG1473	amidohydrolase
EA743_010690	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EA743_010690	COG0475	glutathione-regulated potassium exporter activity
EA743_010700	COG0583	DNA-binding transcription factor activity
EA743_010705	COG1335	isochorismatase
EA743_010715	COG1309	transcriptional regulator
EA743_010755	COG0446	pyridine nucleotide-disulphide oxidoreductase
EA743_010755	COG1902	pentaerythritol trinitrate reductase activity
EA743_010770	COG1012	belongs to the aldehyde dehydrogenase family
EA743_010790	COG2186	Transcriptional regulator
EA743_010800	COG0583	DNA-binding transcription factor activity
EA743_010805	COG4948	Mandelate Racemase Muconate Lactonizing
EA743_010810	COG4829	muconolactone delta-isomerase
EA743_010820	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EA743_010825	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EA743_010830	COG0183	Belongs to the thiolase family
EA743_010835	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EA743_010845	COG1012	belongs to the aldehyde dehydrogenase family
EA743_010855	COG3733	amine oxidase
EA743_010865	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EA743_010875	COG1028	Short-chain dehydrogenase reductase Sdr
EA743_010885	COG4638	Rieske (2fe-2S)
EA743_010905	COG0154	amidase activity
EA743_010915	COG2814	Major facilitator Superfamily
EA743_010940	COG1960	acyl-CoA dehydrogenase activity
EA743_010945	COG0583	DNA-binding transcription factor activity
EA743_010950	COG1414	Transcriptional regulator
EA743_010965	COG2391	methyltransferase activity
EA743_010975	COG4993	Dehydrogenase
EA743_010980	COG3659	wide pore channel activity
EA743_010985	COG3420	alginic acid biosynthetic process
EA743_010990	COG0710	3-dehydroquinate dehydratase activity
EA743_010995	COG3485	protocatechuate 3,4-dioxygenase
EA743_011000	COG3485	protocatechuate 3,4-dioxygenase
EA743_011005	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EA743_011010	COG2271	Major facilitator Superfamily
EA743_011015	COG0596	Alpha beta hydrolase
EA743_011020	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EA743_011025	COG0183	Belongs to the thiolase family
EA743_011030	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EA743_011035	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EA743_011045	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EA743_011050	COG2323	membrane
EA743_011095	COG1902	pentaerythritol trinitrate reductase activity
EA743_011095	COG0446	pyridine nucleotide-disulphide oxidoreductase
EA743_011110	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EA743_011120	COG0542	response to heat
EA743_011125	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EA743_011155	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EA743_011160	COG0569	domain protein
EA743_011165	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EA743_011180	COG4774	siderophore transport
EA743_011185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EA743_011195	COG1585	Membrane protein implicated in regulation of membrane protease activity
EA743_011200	COG2963	transposase activity
EA743_011210	COG4372	Transposase
EA743_011225	COG1294	oxidase, subunit
EA743_011230	COG4890	Cyd operon protein YbgT
EA743_011240	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EA743_011250	COG0552	protein localization to endoplasmic reticulum
EA743_011275	COG0517	IMP dehydrogenase activity
EA743_011275	COG0516	GMP reductase activity
EA743_011280	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EA743_011285	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EA743_011295	COG0583	DNA-binding transcription factor activity
EA743_011300	COG0024	Methionine aminopeptidase
EA743_011330	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EA743_011330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EA743_011335	COG1105	Belongs to the carbohydrate kinase PfkB family
EA743_011340	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EA743_011340	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EA743_011340	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EA743_011355	COG3300	MHYT domain
EA743_011355	COG5001	Diguanylate cyclase
EA743_011365	COG4372	Transposase
EA743_011375	COG2963	transposase activity
EA743_011390	COG2135	peptidase activity
EA743_011395	COG0659	secondary active sulfate transmembrane transporter activity
EA743_011410	COG1113	amino acid transport
EA743_011420	COG1522	sequence-specific DNA binding
EA743_011445	COG1011	Hydrolase
EA743_011450	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EA743_011460	COG2137	regulation of response to DNA damage stimulus
EA743_011475	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EA743_011510	COG0575	Belongs to the CDS family
EA743_011515	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EA743_011540	COG3852	Histidine kinase
EA743_011545	COG2204	response regulator
EA743_011620	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EA743_011625	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EA743_011645	COG0697	spore germination
EA743_011650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EA743_011660	COG0303	'Molybdopterin
EA743_011665	COG0315	cyclic pyranopterin monophosphate synthase activity
EA743_011665	COG0521	Mo-molybdopterin cofactor biosynthetic process
EA743_011680	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EA743_011685	COG0243	molybdopterin cofactor binding
EA743_011695	COG0243	molybdopterin cofactor binding
EA743_011700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EA743_011705	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EA743_011705	COG2146	nitrite reductase [NAD(P)H] activity
EA743_011715	COG0745	RESPONSE REGULATOR receiver
EA743_011720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EA743_011720	COG1116	anion transmembrane transporter activity
EA743_011735	COG0511	ligase activity, forming carbon-carbon bonds
EA743_011750	COG2814	Major facilitator Superfamily
EA743_011840	COG2963	transposase activity
EA743_011850	COG4372	Transposase
EA743_011885	COG0592	DNA-directed DNA polymerase activity
EA743_011930	COG2026	Addiction module toxin, RelE StbE family
EA743_012085	COG2963	transposase activity
EA743_012095	COG4372	Transposase
EA743_012140	COG1484	DNA-dependent DNA replication
EA743_012235	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EA743_012285	COG0069	glutamate synthase activity
EA743_012305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EA743_012315	COG1454	alcohol dehydrogenase
EA743_012320	COG0824	Thioesterase
EA743_012330	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EA743_012360	COG0183	Belongs to the thiolase family
EA743_012370	COG0583	DNA-binding transcription factor activity
EA743_012385	COG4372	Transposase
EA743_012395	COG2963	transposase activity
EA743_012405	COG1522	sequence-specific DNA binding
EA743_012410	COG3135	benzoate transporter
EA743_012420	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EA743_012435	COG0589	response to stress
EA743_012440	COG0488	(ABC) transporter
EA743_012460	COG4773	Receptor
EA743_012490	COG0668	transmembrane transport
EA743_012500	COG1309	transcriptional regulator
EA743_012525	COG1605	Chorismate mutase
EA743_012565	COG0308	aminopeptidase N
EA743_012585	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EA743_012595	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EA743_012600	COG1454	alcohol dehydrogenase
EA743_012620	COG0531	amino acid
EA743_012625	COG4303	Ethanolamine ammonia lyase large subunit
EA743_012630	COG4302	ethanolamine ammonia-lyase activity
EA743_012635	COG0519	Catalyzes the synthesis of GMP from XMP
EA743_012635	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EA743_012640	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EA743_012650	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EA743_012665	COG0697	spore germination
EA743_012670	COG1923	regulation of RNA biosynthetic process
EA743_012680	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EA743_012685	COG0802	atpase or kinase
EA743_012705	COG1187	pseudouridine synthase activity
EA743_012720	COG0583	DNA-binding transcription factor activity
EA743_012735	COG2814	Major facilitator Superfamily
EA743_012740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EA743_012770	COG0729	surface antigen
EA743_012790	COG0174	glutamine synthetase
EA743_012795	COG0745	RESPONSE REGULATOR receiver
EA743_012800	COG2205	protein histidine kinase activity
EA743_012810	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EA743_012815	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EA743_012825	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EA743_012840	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EA743_012845	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EA743_012850	COG1960	acyl-CoA dehydrogenase activity
EA743_012880	COG0583	DNA-binding transcription factor activity
EA743_012900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EA743_012910	COG3658	cytochrome
EA743_012915	COG1215	transferase activity, transferring glycosyl groups
EA743_012920	COG0726	polysaccharide deacetylase
EA743_012920	COG1649	PFAM Uncharacterised BCR, COG1649
EA743_012945	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EA743_012950	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EA743_012960	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EA743_012985	COG0305	Participates in initiation and elongation during chromosome replication
EA743_012990	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EA743_013000	COG1305	Transglutaminase-like
EA743_013010	COG2308	Evidence 4 Homologs of previously reported genes of
EA743_013040	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EA743_013045	COG0138	bifunctional purine biosynthesis protein purh
EA743_013050	COG0151	Belongs to the GarS family
EA743_013055	COG1464	Belongs to the NlpA lipoprotein family
EA743_013060	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EA743_013065	COG2011	ABC-type metal ion transport system permease component
EA743_013070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EA743_013080	COG1301	dicarboxylic acid transport
EA743_013115	COG1794	racemase activity, acting on amino acids and derivatives
EA743_013125	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EA743_013125	COG3008	intermembrane lipid transfer
EA743_013130	COG2995	paraquat-inducible protein a
EA743_013160	COG1051	belongs to the nudix hydrolase family
EA743_013165	COG0477	Major facilitator Superfamily
EA743_013215	COG2186	Transcriptional regulator
EA743_013225	COG0786	glutamate:sodium symporter activity
EA743_013230	COG3243	poly(R)-hydroxyalkanoic acid synthase
EA743_013255	COG3111	PFAM Bacterial OB fold (BOF) protein
EA743_013355	COG2831	hemolysin activation secretion protein
EA743_013380	COG2815	serine threonine protein kinase
EA743_013380	COG0515	serine threonine protein kinase
EA743_013405	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EA743_013410	COG1610	YqeY-like protein
EA743_013415	COG4783	chaperone-mediated protein folding
EA743_013440	COG1286	toxin biosynthetic process
EA743_013470	COG0778	Nitroreductase
EA743_013480	COG0513	Belongs to the DEAD box helicase family
EA743_013500	COG2363	Small membrane protein
EA743_013530	COG1234	tRNA 3'-trailer cleavage
EA743_013535	COG2195	Cleaves the N-terminal amino acid of tripeptides
EA743_013545	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EA743_013555	COG2819	hydrolase of the alpha beta superfamily
EA743_013560	COG1960	acyl-CoA dehydrogenase activity
EA743_013565	COG1301	dicarboxylic acid transport
EA743_013575	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EA743_013580	COG3139	Protein of unknown function (DUF1315)
EA743_013585	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EA743_013590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EA743_013600	COG0494	nUDIX hydrolase
EA743_013610	COG0642	Histidine kinase
EA743_013615	COG0745	RESPONSE REGULATOR receiver
EA743_013635	COG1720	tRNA m6t6A37 methyltransferase activity
EA743_013645	COG0384	phenazine biosynthesis protein PhzF
EA743_013650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EA743_013660	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EA743_013670	COG4598	ABC transporter
EA743_013675	COG4160	amino acid transport
EA743_013680	COG4215	(ABC) transporter
EA743_013695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA743_013705	COG1538	Outer membrane efflux protein
EA743_013740	COG1131	(ABC) transporter
EA743_013745	COG0842	Transport permease protein
EA743_013760	COG0772	Belongs to the SEDS family
EA743_013765	COG2951	lytic endotransglycosylase activity
EA743_013790	COG2207	Transcriptional regulator
EA743_013805	COG0052	Belongs to the universal ribosomal protein uS2 family
EA743_013810	COG0024	Methionine aminopeptidase
EA743_013820	COG2223	nitrite transmembrane transporter activity
EA743_013830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EA743_013835	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EA743_013840	COG1960	acyl-CoA dehydrogenase activity
EA743_013855	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EA743_013860	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EA743_013865	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EA743_013885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EA743_013890	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EA743_013895	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EA743_013930	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EA743_013945	COG3104	oligopeptide transport
EA743_013955	COG0582	viral genome integration into host DNA
EA743_014335	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EA743_014360	COG3384	dioxygenase
EA743_014370	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EA743_014375	COG2878	Part of a membrane complex involved in electron transport
EA743_014380	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EA743_014405	COG0768	penicillin binding
EA743_014410	COG0742	ribosomal rna small subunit methyltransferase
EA743_014425	COG0830	nickel cation binding
EA743_014435	COG0804	urea catabolic process
EA743_014475	COG1253	flavin adenine dinucleotide binding
EA743_014485	COG2851	Citrate transporter
EA743_014535	COG1773	rubredoxin
EA743_014540	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EA743_014550	COG0583	DNA-binding transcription factor activity
EA743_014580	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EA743_014585	COG4181	ATPase activity
EA743_014630	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EA743_014650	COG0306	phosphate transporter
EA743_014660	COG3958	Transketolase
EA743_014665	COG3959	Transketolase, thiamine diphosphate binding domain
EA743_014670	COG2271	Major facilitator Superfamily
EA743_014675	COG1028	Short-chain dehydrogenase reductase Sdr
EA743_014680	COG0583	DNA-binding transcription factor activity
EA743_014700	COG2223	nitrite transmembrane transporter activity
EA743_014705	COG2207	Transcriptional regulator
EA743_014710	COG2066	Belongs to the glutaminase family
EA743_014715	COG0242	peptide deformylase activity
EA743_014720	COG0477	Major facilitator Superfamily
EA743_014730	COG0028	Belongs to the TPP enzyme family
EA743_014745	COG1028	Short-chain dehydrogenase reductase Sdr
EA743_014750	COG2267	carboxylic ester hydrolase activity
EA743_014760	COG2271	Major facilitator Superfamily
EA743_014775	COG1028	Short-chain dehydrogenase reductase Sdr
EA743_014795	COG1414	Transcriptional regulator
EA743_014810	COG1024	Enoyl-CoA hydratase
EA743_014820	COG1215	transferase activity, transferring glycosyl groups
EA743_014825	COG0726	polysaccharide deacetylase
EA743_014825	COG1649	PFAM Uncharacterised BCR, COG1649
EA743_014835	COG4681	YaeQ
EA743_014845	COG0523	cobalamin synthesis protein
EA743_014855	COG1607	acyl-coa hydrolase
EA743_014865	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EA743_014870	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EA743_014875	COG1309	transcriptional regulator
EA743_014900	COG2040	homocysteine
EA743_014905	COG0531	amino acid
EA743_014955	COG0477	Major facilitator Superfamily
EA743_014990	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EA743_015005	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EA743_015010	COG2963	transposase activity
EA743_015020	COG4372	Transposase
EA743_015065	COG0629	single-stranded DNA binding
EA743_015110	COG0582	viral genome integration into host DNA
EA743_015120	COG0405	Gamma-glutamyltransferase
EA743_015125	COG2814	Major facilitator Superfamily
EA743_015135	COG2050	protein possibly involved in aromatic compounds catabolism
EA743_015150	COG1090	epimerase
EA743_015170	COG0420	3'-5' exonuclease activity
EA743_015195	COG0735	belongs to the Fur family
EA743_015200	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EA743_015225	COG0121	glutamine amidotransferase
EA743_015240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EA743_015250	COG0210	DNA helicase
EA743_015255	COG2885	chlorophyll binding
EA743_015260	COG0204	Acyl-transferase
EA743_015275	COG2894	cell division
EA743_015290	COG1280	lysine exporter protein (LysE YggA)
EA743_015295	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EA743_015295	COG1674	ftsk spoiiie
EA743_015300	COG0492	ferredoxin-NADP+ reductase activity
EA743_015305	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EA743_015315	COG0456	acetyltransferase
EA743_015375	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EA743_015375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EA743_015395	COG1012	belongs to the aldehyde dehydrogenase family
EA743_015415	COG0473	3-isopropylmalate dehydrogenase activity
EA743_015420	COG0583	DNA-binding transcription factor activity
EA743_015440	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EA743_015465	COG0564	pseudouridine synthase activity
EA743_015475	COG0358	DNA primase activity
EA743_015490	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EA743_015520	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EA743_015550	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EA743_015560	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EA743_015560	COG0352	thiamine-phosphate diphosphorylase activity
EA743_015560	COG0351	phosphomethylpyrimidine kinase
EA743_015565	COG1652	LysM domain
EA743_015590	COG1399	metal-binding, possibly nucleic acid-binding protein
EA743_015595	COG3101	peptidyl-lysine hydroxylation
EA743_015600	COG0009	L-threonylcarbamoyladenylate synthase
EA743_015605	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EA743_015610	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EA743_015625	COG4106	trans-aconitate 2-methyltransferase activity
EA743_015640	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EA743_015640	COG0596	Alpha beta hydrolase
EA743_015640	COG2226	methyltransferase
EA743_015645	COG1877	trehalose-phosphatase activity
EA743_015650	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
EA743_015655	COG2223	nitrite transmembrane transporter activity
EA743_015675	COG1196	nuclear chromosome segregation
EA743_015685	COG0730	response to heat
EA743_015700	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EA743_015710	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EA743_015770	COG0489	protein tyrosine kinase activity
EA743_015780	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EA743_015780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EA743_015810	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EA743_015815	COG2081	HI0933 family
EA743_015825	COG0668	transmembrane transport
EA743_015845	COG0583	DNA-binding transcription factor activity
EA743_015870	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EA743_015875	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EA743_015905	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EA743_015930	COG3706	GGDEF domain
EA743_015940	COG2205	protein histidine kinase activity
EA743_015945	COG0745	RESPONSE REGULATOR receiver
EA743_015965	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EA743_016020	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EA743_016025	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EA743_016035	COG0583	DNA-binding transcription factor activity
EA743_016045	COG0583	DNA-binding transcription factor activity
EA743_016065	COG0583	DNA-binding transcription factor activity
EA743_016070	COG1053	succinate dehydrogenase
EA743_016085	COG1309	transcriptional regulator
EA743_016090	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EA743_016095	COG2814	Major facilitator Superfamily
EA743_016100	COG1960	acyl-CoA dehydrogenase activity
EA743_016105	COG0583	DNA-binding transcription factor activity
EA743_016110	COG1063	alcohol dehydrogenase
EA743_016140	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EA743_016145	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EA743_016150	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EA743_016170	COG2132	Multicopper oxidase
EA743_016180	COG0561	phosphatase activity
EA743_016185	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EA743_016210	COG1214	PFAM Peptidase M22, glycoprotease
EA743_016240	COG4372	Transposase
EA743_016250	COG2963	transposase activity
EA743_016280	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EA743_016290	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EA743_016295	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EA743_016300	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EA743_016360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EA743_016370	COG1846	Transcriptional regulator
EA743_016375	COG1764	response to oxidative stress
EA743_016415	COG0037	tRNA processing
EA743_016425	COG0248	Ppx GppA phosphatase
EA743_016455	COG0072	phenylalanine-tRNA ligase activity
EA743_016480	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EA743_016495	COG1238	metal cluster binding
EA743_016500	COG0625	glutathione transferase activity
EA743_016520	COG0318	PFAM AMP-dependent synthetase and ligase
EA743_016525	COG3028	Belongs to the UPF0307 family
EA743_016530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EA743_016550	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EA743_016555	COG0617	tRNA 3'-terminal CCA addition
EA743_016560	COG1555	photosystem II stabilization
EA743_016565	COG3956	TIGRFAM MazG family protein
EA743_016575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EA743_016595	COG5002	protein histidine kinase activity
EA743_016595	COG2205	protein histidine kinase activity
EA743_016595	COG0784	Response regulator, receiver
EA743_016600	COG1024	Enoyl-CoA hydratase
EA743_016605	COG2084	Dehydrogenase
EA743_016610	COG3622	Belongs to the hyi family
EA743_016625	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EA743_016630	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EA743_016635	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EA743_016640	COG0697	spore germination
EA743_016650	COG2814	Major facilitator Superfamily
EA743_016655	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EA743_016665	COG0583	DNA-binding transcription factor activity
EA743_016675	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EA743_016685	COG0084	hydrolase, TatD family'
EA743_016700	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EA743_016735	COG0440	acetolactate synthase activity
EA743_016740	COG0028	Belongs to the TPP enzyme family
EA743_016770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA743_016775	COG1136	(ABC) transporter
EA743_016775	COG0577	efflux transmembrane transporter activity
EA743_016780	COG1538	Outer membrane efflux protein
EA743_016795	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EA743_016800	COG1162	GTPase activity
EA743_016810	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EA743_016850	COG1426	Protein conserved in bacteria
EA743_016885	COG0793	Belongs to the peptidase S41A family
EA743_016900	COG2267	carboxylic ester hydrolase activity
EA743_016910	COG1012	belongs to the aldehyde dehydrogenase family
EA743_016915	COG3265	gluconokinase activity
EA743_016935	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EA743_016940	COG0280	phosphate acetyltransferase
EA743_016940	COG0857	belongs to the CobB CobQ family
EA743_016945	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EA743_016945	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EA743_016965	COG0740	serine-type endopeptidase activity
EA743_016975	COG4774	siderophore transport
EA743_016985	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EA743_016995	COG2813	Specifically methylates the guanine in position
EA743_016995	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EA743_017095	COG0788	formyltetrahydrofolate deformylase activity
EA743_017110	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EA743_017115	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EA743_017120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EA743_017120	COG4651	solute:proton antiporter activity
EA743_017140	COG0724	RNA recognition motif
EA743_017145	COG0210	DNA helicase
EA743_017170	COG1733	regulation of RNA biosynthetic process
EA743_017190	COG1280	lysine exporter protein (LysE YggA)
EA743_017195	COG1560	Kdo2-lipid A biosynthetic process
EA743_017205	COG1301	dicarboxylic acid transport
EA743_017260	COG0473	3-isopropylmalate dehydrogenase activity
EA743_017325	COG0583	DNA-binding transcription factor activity
EA743_017335	COG0625	glutathione transferase activity
EA743_017340	COG2378	regulation of single-species biofilm formation
EA743_017345	COG0546	phosphoglycolate phosphatase activity
EA743_017360	COG1530	ribonuclease E activity
EA743_017380	COG0583	DNA-binding transcription factor activity
EA743_017385	COG1028	Short-chain dehydrogenase reductase Sdr
EA743_017390	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EA743_017400	COG0534	Mate efflux family protein
EA743_017415	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EA743_017425	COG4372	Transposase
EA743_017435	COG2963	transposase activity
EA743_017470	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EA743_017475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EA743_017490	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EA743_017500	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EA743_017500	COG0644	oxidoreductase
EA743_017510	COG0425	Belongs to the sulfur carrier protein TusA family
EA743_017515	COG4535	Mg2 and Co2 transporter CorC
EA743_017525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EA743_017545	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EA743_017550	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EA743_017550	COG0475	glutathione-regulated potassium exporter activity
EA743_017565	COG0484	heat shock protein binding
EA743_017570	COG0789	Transcriptional regulator
EA743_017575	COG0598	Magnesium transport protein CorA
EA743_017595	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EA743_017600	COG1074	ATP-dependent DNA helicase activity
EA743_017605	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EA743_017625	COG2226	methyltransferase
EA743_017640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EA743_017645	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EA743_017660	COG2111	Na H antiporter
EA743_017660	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EA743_017665	COG1006	Multisubunit Na H antiporter MnhC subunit
EA743_017670	COG0651	ATP synthesis coupled electron transport
EA743_017680	COG2212	antiporter activity
EA743_017700	COG0195	Participates in both transcription termination and antitermination
EA743_017750	COG0237	dephospho-CoA kinase activity
EA743_017760	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EA743_017775	COG0497	DNA recombination
EA743_017785	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EA743_017815	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EA743_017815	COG2169	Transcriptional regulator
EA743_017820	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EA743_017870	COG0789	Transcriptional regulator
EA743_017880	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EA743_017895	COG0326	Molecular chaperone. Has ATPase activity
EA743_017910	COG2056	Na+-H+ antiporter family
EA743_018010	COG0546	phosphoglycolate phosphatase activity
EA743_018015	COG1716	ATPase activity
EA743_018060	COG0181	hydroxymethylbilane synthase activity
EA743_018070	COG3275	phosphorelay sensor kinase activity
EA743_018090	COG1538	Outer membrane efflux protein
EA743_018095	COG0697	spore germination
EA743_018120	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EA743_018125	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EA743_018130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EA743_018135	COG0772	Belongs to the SEDS family
EA743_018160	COG4974	Belongs to the 'phage' integrase family
EA743_018165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EA743_018175	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EA743_018185	COG2197	response regulator
EA743_018200	COG0793	Belongs to the peptidase S41A family
EA743_018205	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EA743_018210	COG0795	lipopolysaccharide-transporting ATPase activity
EA743_018250	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EA743_018250	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EA743_018260	COG0004	ammonium transporteR
EA743_018265	COG0347	Belongs to the P(II) protein family
EA743_018275	COG0606	chelatase, subunit chli
EA743_018345	COG2132	Multicopper oxidase
EA743_018360	COG2205	protein histidine kinase activity
EA743_018365	COG2217	Heavy metal translocating P-type atpase
EA743_018410	COG0606	chelatase, subunit chli
EA743_018415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EA743_018420	COG0235	Class ii aldolase
EA743_018425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EA743_018440	COG2963	transposase activity
EA743_018450	COG4372	Transposase
EA743_018455	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EA743_018470	COG0318	PFAM AMP-dependent synthetase and ligase
EA743_018480	COG0477	Major facilitator Superfamily
EA743_018485	COG2860	membrane
EA743_018490	COG3012	SEC-C Motif Domain Protein
EA743_018495	COG1253	flavin adenine dinucleotide binding
EA743_018505	COG2814	Major facilitator Superfamily
EA743_018515	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EA743_018550	COG0655	NAD(P)H dehydrogenase (quinone) activity
EA743_018560	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EA743_018595	COG1309	transcriptional regulator
EA743_018630	COG0758	DNA mediated transformation
EA743_018640	COG0697	spore germination
EA743_018645	COG1309	transcriptional regulator
EA743_018660	COG0386	Belongs to the glutathione peroxidase family
EA743_018730	COG1121	(ABC) transporter
EA743_018735	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EA743_018740	COG1280	lysine exporter protein (LysE YggA)
EA743_018745	COG2837	iron assimilation
EA743_018755	COG0281	malic enzyme
EA743_018800	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EA743_018800	COG0519	Catalyzes the synthesis of GMP from XMP
EA743_018805	COG4399	Belongs to the UPF0754 family
EA743_018810	COG2259	Doxx family
EA743_018815	COG0586	Pfam SNARE associated Golgi protein
EA743_018830	COG1192	Involved in chromosome partitioning
EA743_018840	COG0271	Belongs to the BolA IbaG family
EA743_018860	COG4372	Transposase
EA743_018870	COG2963	transposase activity
EA743_018900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EA743_018900	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EA743_018900	COG3321	synthase
EA743_018900	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EA743_018905	COG1960	acyl-CoA dehydrogenase activity
EA743_018915	COG2197	response regulator
EA743_018925	COG3916	Acyl-homoserine-lactone synthase
EA743_018930	COG0477	Major facilitator Superfamily
EA743_018935	COG1024	Enoyl-CoA hydratase
EA743_018940	COG1024	Enoyl-CoA hydratase
EA743_018945	COG1960	acyl-CoA dehydrogenase activity
EA743_018950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EA743_018970	COG1113	amino acid transport
EA743_018975	COG1113	amino acid transport
EA743_018980	COG0251	oxidation-reduction process
EA743_018995	COG1522	sequence-specific DNA binding
EA743_019020	COG0564	pseudouridine synthase activity
EA743_019090	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EA743_019105	COG1802	Transcriptional regulator
EA743_019115	COG1448	Aminotransferase
EA743_019120	COG0277	FAD linked oxidase domain protein
EA743_019130	COG2186	Transcriptional regulator
EA743_019140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EA743_019145	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EA743_019160	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EA743_019165	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EA743_019170	COG1216	Glycosyl transferase, family 2
EA743_019190	COG0438	transferase activity, transferring glycosyl groups
EA743_019220	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EA743_019250	COG0728	peptidoglycan biosynthetic process
EA743_019255	COG3023	N-Acetylmuramoyl-L-alanine amidase
EA743_019310	COG0546	phosphoglycolate phosphatase activity
EA743_019315	COG1028	Short-chain dehydrogenase reductase Sdr
EA743_019335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EA743_019340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EA743_019345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EA743_019350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EA743_019355	COG1116	anion transmembrane transporter activity
EA743_019360	COG1309	transcriptional regulator
EA743_019365	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EA743_019375	COG0196	riboflavin kinase activity
EA743_019380	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EA743_019390	COG1047	Peptidyl-prolyl cis-trans
EA743_019430	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EA743_019485	COG2951	lytic endotransglycosylase activity
EA743_019490	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EA743_019510	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EA743_019520	COG0671	phosphoesterase, PA-phosphatase related
EA743_019525	COG0861	Integral membrane protein TerC family
EA743_019535	COG0754	glutathionylspermidine amidase activity
EA743_019545	COG0402	S-adenosylhomocysteine deaminase activity
EA743_019560	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EA743_019565	COG1230	cation diffusion facilitator family transporter
EA743_019580	COG0706	membrane insertase activity
EA743_019595	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EA743_019730	COG2161	toxin-antitoxin pair type II binding
EA743_019850	COG4974	Belongs to the 'phage' integrase family
EA743_019865	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII