locus-tag class description M3Q_10 ENOG4105EUB pirin domain protein M3Q_100 ENOG4105IPS esterase M3Q_1000 ENOG4105HF0 Membrane M3Q_1002 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) M3Q_1006 ENOG4106UW1 Major Facilitator superfamily M3Q_1007 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase M3Q_1008 ENOG4108K4C ec 3.1.3.12 M3Q_1009 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) M3Q_1011 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) M3Q_1012 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) M3Q_1014 ENOG4105FE9 pseudouridine synthase M3Q_1015 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) M3Q_1016 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) M3Q_1017 ENOG4107RTD sua5 ycio yrdc ywlc family protein M3Q_1018 ENOG4108BPE -transporting atpase M3Q_1019 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein M3Q_1021 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase M3Q_1022 ENOG4105CHR reductase M3Q_1023 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) M3Q_1024 ENOG4109066 lysm domain bon superfamily protein M3Q_1025 ENOG4105DWF phosphomethylpyrimidine kinase M3Q_1027 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) M3Q_1033 ENOG4105C5T Phosphoribosyl pyrophosphate synthase M3Q_1035 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) M3Q_1038 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) M3Q_1039 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane M3Q_1040 ENOG4105C34 Pseudouridine synthase M3Q_1041 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase M3Q_1045 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding M3Q_1047 ENOG4105EJC lysr family transcriptional regulator M3Q_1048 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) M3Q_1049 ENOG4105C94 Transporter M3Q_1051 ENOG4105DVW rieske (2Fe-2S) M3Q_1052 ENOG4105C26 Dehydrogenase M3Q_1053 ENOG4105E3J oxidoreductase M3Q_1055 ENOG4105C4K Nad synthetase M3Q_1057 ENOG4105EUB pirin domain protein M3Q_1058 ENOG4108YXA Membrane M3Q_1067 ENOG4105KEG ribosomal-protein-alanine acetyltransferase M3Q_1069 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) M3Q_1070 ENOG4105C3M thioredoxin reductase M3Q_1071 ENOG4105CNU cell division protein FtsK M3Q_1076 ENOG4107QMS site-determining protein M3Q_1079 ENOG4106HNH Acyl-transferase M3Q_1080 ENOG4108ZG0 Ompa motb domain protein M3Q_1081 ENOG4105C4R Atp-dependent dna helicase M3Q_1083 ENOG4107QKV phosphomannomutase M3Q_1086 ENOG4105E7A Glutamine amidotransferase M3Q_1091 ENOG41090R7 Ferric uptake M3Q_1092 ENOG4105CZX twitching motility protein M3Q_1093 ENOG4105CZX twitching motility protein M3Q_1094 ENOG4105DFA alanine racemase domain protein M3Q_1095 ENOG4105EYH Exonuclease M3Q_1096 ENOG4107RH8 nuclease SbcCD subunit D M3Q_11 ENOG4105CHJ isochorismatase hydrolase M3Q_110 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase M3Q_1100 ENOG4105ECP epimerase M3Q_1101 ENOG4105MWK D-amino acid dehydrogenase, small subunit M3Q_1102 ENOG4105D52 delta-aminolevulinic acid dehydratase M3Q_1103 ENOG4108VUY thioesterase Superfamily protein M3Q_1104 ENOG4105CW7 secretion protein, HlyD family M3Q_1105 ENOG4105C0R drug resistance transporter emrb qaca subfamily M3Q_1106 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) M3Q_111 ENOG4105CS6 Rhs element vgr protein M3Q_1119 ENOG41083X2 DNA polymerase III, epsilon subunit M3Q_114 ENOG4105D9M gamma-glutamylcysteine synthetase M3Q_1146 ENOG4105VTN Protein of unknown function (DUF1311) M3Q_117 ENOG4106BRA Membrane M3Q_1175 ENOG4105K4U addiction module toxin, RelE StbE family M3Q_118 ENOG4105CHM Aminotransferase M3Q_1183 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) M3Q_119 ENOG4107QJQ Mate efflux family protein M3Q_1207 ENOG4105C54 Major Facilitator superfamily M3Q_1208 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) M3Q_1210 ENOG4108SF5 RNA Polymerase M3Q_1216 ENOG4108YNN Heme oxygenase M3Q_122 ENOG4105CK6 Two component transcriptional regulator (Winged helix family M3Q_1221 ENOG4105D5Q Arginine ornithine antiporter M3Q_1222 ENOG4107QK5 Homocysteine s-methyltransferase M3Q_1227 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) M3Q_1228 ENOG4105C94 Transporter M3Q_1229 ENOG4105C94 Transporter M3Q_123 ENOG4105BZU Histidine kinase M3Q_1233 ENOG4105CKI cobalamin synthesis protein M3Q_1235 ENOG4108VWS Yaeq family M3Q_1237 ENOG4107BJW polysaccharide deacetylase M3Q_1238 ENOG4105CND Glycosyl transferase, family 2 M3Q_1240 ENOG4106YT9 Enoyl-CoA hydratase M3Q_1243 ENOG41069M3 Transcriptional regulator M3Q_1247 ENOG4105CHR reductase M3Q_1249 ENOG4108DNI pyridine nucleotide-disulfide oxidoreductase M3Q_1250 ENOG4105DJB Major Facilitator Superfamily M3Q_1252 ENOG4108MXF Alpha Beta Hydrolase M3Q_1253 ENOG4105CHR reductase M3Q_1256 ENOG4105C7K acetolactate synthase M3Q_1258 ENOG4105CSH Transporter M3Q_1259 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) M3Q_126 ENOG4105KHC sulfurtransferase M3Q_1260 ENOG4105CSV Glutaminase M3Q_1261 ENOG4108R6W Transcriptional regulator, ARAC family M3Q_1262 ENOG4105EU0 Major facilitator Superfamily M3Q_1263 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) M3Q_1265 ENOG4108PZW LysR family Transcriptional regulator M3Q_1267 ENOG4105CSP Major Facilitator Superfamily M3Q_1270 ENOG4105C3R Methionine synthase M3Q_1271 ENOG4105CJ3 phosphate transporter M3Q_1275 ENOG4105E6M Sulphatase-modifying factor protein M3Q_1276 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) M3Q_1279 ENOG4107RNH Outer membrane receptor FepA M3Q_1283 ENOG4108UJV acyl-CoA thioesterase i M3Q_1284 ENOG4108I0Y (ABC) transporter M3Q_1285 ENOG4105CV6 ABC transporter, permease M3Q_1286 ENOG4107U91 Rhomboid family M3Q_1290 ENOG4105C5Q Transcriptional regulator M3Q_1292 ENOG4107QZF nitrite reductase NADPH large subunit M3Q_1293 ENOG4105VCQ rubredoxin M3Q_1297 ENOG4108MRJ M3Q_13 ENOG4105C26 Dehydrogenase M3Q_1300 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) M3Q_1303 ENOG4105D4T Citrate transporter M3Q_1304 ENOG4105C37 (CBS) domain M3Q_1306 ENOG4107RET Isocitrate lyase M3Q_1312 ENOG4105CQM Urea amidohydrolase subunit alpha M3Q_1314 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) M3Q_1317 ENOG4106H78 methyltransferase M3Q_1318 ENOG4105CJN penicillin-binding protein M3Q_1322 ENOG4105CSM endonuclease III M3Q_1323 ENOG4108R3D Electron transport complex M3Q_1324 ENOG4105D82 Glutamate dehydrogenase M3Q_1326 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b M3Q_133 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) M3Q_1331 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase M3Q_136 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) M3Q_137 ENOG4108ZAI phosphatidylglycerophosphatase a M3Q_139 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) M3Q_1390 ENOG4105DR5 peptidase M3Q_1399 ENOG4105DIJ Phosphoethanolamine transferase M3Q_14 ENOG4108JPW Aminotransferase M3Q_140 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) M3Q_141 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 M3Q_1410 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) M3Q_1415 ENOG4105CDU Replicative dna helicase M3Q_143 ENOG41088SP formiminoglutamate hydrolase M3Q_1434 ENOG4105EFC phage portal protein HK97 family M3Q_1446 ENOG4105E4C Lytic transglycosylase catalytic M3Q_145 ENOG4105C85 amino acid M3Q_1461 ENOG4107RAQ aminopeptidase M3Q_1462 ENOG4105D0A hydroxylase M3Q_1463 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family M3Q_1467 ENOG4108ZUB Lysine exporter protein (Lyse ygga) M3Q_1468 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) M3Q_1470 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) M3Q_1472 ENOG4105W4M Transport-associated protein M3Q_1474 ENOG4105E09 nadh pyrophosphatase M3Q_1476 ENOG4107RZZ dna polymerase iii epsilon subunit M3Q_1477 ENOG4105E9H Lytic Murein transglycosylase M3Q_1477 ENOG4105E9H Lytic Murein transglycosylase M3Q_1479 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component M3Q_148 ENOG41090B9 response to stress M3Q_1480 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component M3Q_1481 ENOG4108JQ5 ABC transporter M3Q_1484 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) M3Q_1488 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase M3Q_149 ENOG4105CZE histidine utilization repressor M3Q_1490 ENOG4108M3P Membrane M3Q_1491 ENOG4105D01 (LipO)protein M3Q_1495 ENOG4105CNA YD repeat protein M3Q_1503 ENOG4105C85 amino acid M3Q_1505 ENOG4105CUB amino acid M3Q_1509 ENOG4105C26 Dehydrogenase M3Q_151 ENOG4105CKI cobalamin synthesis protein M3Q_1513 ENOG4105C85 amino acid M3Q_1515 ENOG4105D13 transposase M3Q_1516 ENOG4108C33 Resolvase M3Q_1522 ENOG4105F95 Monooxygenase M3Q_1524 ENOG4105C7N Xanthine uracil vitamin C permease M3Q_1525 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) M3Q_1526 ENOG4105CPW cytochrome b561 M3Q_1528 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) M3Q_153 ENOG4105C85 amino acid M3Q_1530 ENOG4105CFH Aspartokinase M3Q_1532 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase M3Q_1534 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis M3Q_1537 ENOG4105CPC Aldo Keto reductase M3Q_1540 ENOG4107RYR Transcriptional regulator, Crp Fnr family M3Q_1541 ENOG4108UKZ OsmC family M3Q_1544 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit M3Q_155 ENOG4108RXX maleylacetoacetate isomerase M3Q_1550 ENOG4105CD3 dihydroorotase M3Q_1551 ENOG4108ZG0 Ompa motb domain protein M3Q_1553 ENOG4108TGY Glutathione S-transferase M3Q_1554 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) M3Q_1556 ENOG4108K3A Glutathione S-transferase M3Q_1558 ENOG4108JU3 Alkyl hydroperoxide reductase M3Q_1560 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) M3Q_1562 ENOG4105D3R alkyl hydroperoxide reductase M3Q_1563 ENOG4105CQ7 ATP-dependent helicase M3Q_1566 ENOG4105D2S major facilitator superfamily M3Q_1567 ENOG4105DKK Benzoate M3Q_1568 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase M3Q_1569 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein M3Q_1570 ENOG4108UKV benzoate 1,2-dioxygenase M3Q_1571 ENOG4105FUY alpha subunit M3Q_1572 ENOG4108KB2 LysR family Transcriptional regulator M3Q_1582 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) M3Q_1588 ENOG410829K Lysine exporter protein (Lyse ygga) M3Q_1589 ENOG4105VEQ Cold shock protein M3Q_159 ENOG4105EWC Purine nucleoside phosphorylase M3Q_1591 ENOG4105II7 pyrroline-5-carboxylate reductase M3Q_1597 ENOG4107YPT transcriptional regulator M3Q_16 ENOG4105C85 amino acid M3Q_160 ENOG4107QI1 Mate efflux family protein M3Q_1603 ENOG4105C2X Arabinose 5-phosphate isomerase M3Q_1604 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase M3Q_1606 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA M3Q_1607 ENOG4108IUZ ABC transporter M3Q_1608 ENOG4105DFG type I secretion outer membrane protein M3Q_161 ENOG4105C09 Bile acid M3Q_1616 ENOG4108Z4U Ferredoxin M3Q_162 ENOG4108RWI nicotinamidase M3Q_1620 ENOG4107AQZ Membrane M3Q_1621 ENOG4105BZU Histidine kinase M3Q_1622 ENOG4105D1S lipid A biosynthesis M3Q_1624 ENOG4105D2S major facilitator superfamily M3Q_1628 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) M3Q_163 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) M3Q_1634 ENOG4105CNA YD repeat protein M3Q_1638 ENOG4105C5A transporter M3Q_1642 ENOG4108JIK carboxylase M3Q_1643 ENOG4107R4J Chloride channel M3Q_1648 ENOG4105R8C Transcriptional regulator M3Q_1650 ENOG4105E2A Dehydrogenase M3Q_1653 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase M3Q_1654 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF M3Q_1655 ENOG4105KVH Transcriptional regulator M3Q_1658 ENOG4105MRR Transcriptional regulator (By similarity) M3Q_1660 ENOG4108HW3 (ABC) transporter M3Q_167 ENOG4105S64 Formate nitrite transporter M3Q_1674 ENOG4105UYK outer membrane protein a M3Q_1676 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit M3Q_168 ENOG4105D1H recombination factor protein RarA M3Q_1682 ENOG4105EMY transcriptional regulator M3Q_1685 ENOG4105DJ2 Major Facilitator Superfamily M3Q_1688 ENOG4105WPN DNA integration recombination invertion protein M3Q_1693 ENOG4105CZJ Aldehyde dehydrogenase M3Q_1694 ENOG4107QTZ amino acid M3Q_1695 ENOG4105EJQ L-serine dehydratase M3Q_1696 ENOG4105DXM phenylacetic acid degradation protein M3Q_1697 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit M3Q_1698 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit M3Q_1699 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit M3Q_170 ENOG4108ZZ3 UPF0260 protein M3Q_1700 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit M3Q_1701 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) M3Q_1702 ENOG4105E39 Enoyl-CoA hydratase M3Q_1703 ENOG4108UKI Enoyl-CoA hydratase M3Q_1704 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase M3Q_1705 ENOG4105CHU acetyl-coa acetyltransferase M3Q_1706 ENOG4105DZS Phenylacetate-CoA ligase M3Q_1707 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein M3Q_1709 ENOG4108ZJI phenylacetic acid degradation protein M3Q_1716 ENOG4107VGR Catalase M3Q_1717 ENOG4105CPW cytochrome b561 M3Q_1721 ENOG4108MXF Alpha Beta Hydrolase M3Q_1722 ENOG4105MXW flavin reductase domain protein, FMN-binding M3Q_1723 ENOG4108M8W Monooxygenase M3Q_1724 ENOG4105C26 Dehydrogenase M3Q_1725 ENOG4105ETS cytosine purines uracil thiamine allantoin M3Q_1727 ENOG4105C26 Dehydrogenase M3Q_1728 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase M3Q_1729 ENOG4105HEI LysR family (Transcriptional regulator M3Q_1731 ENOG4107HP6 Transcriptional regulator M3Q_1732 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase M3Q_1734 ENOG4105C4Y ABC transporter M3Q_1735 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) M3Q_1736 ENOG4107RCV ABC transporter, permease M3Q_1738 ENOG4107STF Involved in phosphonate degradation (By similarity) M3Q_1739 ENOG4108KAZ Involved in phosphonate degradation (By similarity) M3Q_174 ENOG4105CEN a g-specific adenine glycosylase M3Q_1740 ENOG4107RGD Major Facilitator superfamily M3Q_1741 ENOG4105C1G acyl-Coa dehydrogenase M3Q_1744 ENOG4108UKI Enoyl-CoA hydratase M3Q_1745 ENOG4105EA8 2-Nitropropane dioxygenase M3Q_1746 ENOG4105EQ0 Major Facilitator superfamily M3Q_1748 ENOG4105CHU acetyl-coa acetyltransferase M3Q_1749 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase M3Q_1750 ENOG4105CHR reductase M3Q_1751 ENOG4105E39 Enoyl-CoA hydratase M3Q_1752 ENOG4105C1G acyl-Coa dehydrogenase M3Q_1753 ENOG4107RGD Major Facilitator superfamily M3Q_1754 ENOG4107QP7 CoA-transferase subunit A M3Q_1755 ENOG4107QNJ CoA-transferase subunit B M3Q_1757 ENOG4105EQ0 Major Facilitator superfamily M3Q_1759 ENOG4105CSU acyl-Coa dehydrogenase M3Q_1762 ENOG4105CC0 LysR family Transcriptional regulator M3Q_1765 ENOG4105E39 Enoyl-CoA hydratase M3Q_1766 ENOG4107QX3 carboxylase M3Q_1767 ENOG4105C1G acyl-Coa dehydrogenase M3Q_1768 ENOG4105R8C Transcriptional regulator M3Q_1769 ENOG4105CEY Amp-dependent synthetase and ligase M3Q_177 ENOG4108R3E Dna-3-methyladenine glycosylase i M3Q_1773 ENOG4105HEI LysR family (Transcriptional regulator M3Q_178 ENOG4105DQ4 alcohol dehydrogenase M3Q_1784 ENOG4105CYX Short-chain dehydrogenase reductase Sdr M3Q_1787 ENOG4105KT5 UmuD protein M3Q_1789 ENOG4105EW9 transcriptional regulator AsnC family M3Q_1791 ENOG4105BZU Histidine kinase M3Q_1792 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase M3Q_1794 ENOG4105EAD ABC transporter M3Q_1795 ENOG4108HW4 amino acid AbC transporter M3Q_1796 ENOG4105CDA abc transporter atp-binding protein M3Q_1797 ENOG4107RP9 extracellular solute-binding protein, family 3 M3Q_1798 ENOG4105CT1 (ABC) transporter M3Q_1799 ENOG4105EXG Transcriptional regulator M3Q_18 ENOG4108UMN azlc family M3Q_1801 ENOG4105C9B Cysteine desulfurase M3Q_1802 ENOG4105ESN nucleotide-binding protein M3Q_1803 ENOG4105D7W serine acetyltransferase M3Q_1805 ENOG4105CHR reductase M3Q_1806 ENOG4105CBN LysR family transcriptional regulator M3Q_1807 ENOG4105CYM Glutathione S-transferase M3Q_1808 ENOG4108SHQ Glutathione S-transferase M3Q_1809 ENOG4105CMU LysR family (Transcriptional regulator M3Q_181 ENOG4105HEI LysR family (Transcriptional regulator M3Q_1810 ENOG4105VAW lrga family M3Q_1811 ENOG41067MG lrgb family M3Q_1815 ENOG4105DXI Major Facilitator superfamily M3Q_1817 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase M3Q_1818 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) M3Q_182 ENOG4105CV8 reductase M3Q_1821 ENOG4105PSI phosphoribosyl-dephospho-CoA transferase M3Q_1822 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase M3Q_1825 ENOG4108K70 Transcriptional regulator M3Q_1826 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family M3Q_1828 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii M3Q_1829 ENOG4105C4M (Ubiquinol oxidase) subunit I M3Q_183 ENOG4105F27 Major Facilitator M3Q_1833 ENOG4105C54 Major Facilitator superfamily M3Q_1836 ENOG4106FTQ Taurine ABC transporter, periplasmic M3Q_1837 ENOG4108IY8 ABC, transporter M3Q_1838 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component M3Q_1839 ENOG4105E2B Taurine dioxygenase M3Q_1841 ENOG4105D2S major facilitator superfamily M3Q_1842 ENOG4107RCI amp-dependent synthetase and ligase M3Q_1843 ENOG4105C1G acyl-Coa dehydrogenase M3Q_1846 ENOG4105CEY Amp-dependent synthetase and ligase M3Q_1849 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) M3Q_1851 ENOG4107PSF BolA-like protein M3Q_1852 ENOG4105C0B DNA polymerase III (alpha subunit) M3Q_1855 ENOG4105CHM Aminotransferase M3Q_1857 ENOG4108V06 Glutathione peroxidase M3Q_1858 ENOG4105E7U AraC family transcriptional regulator M3Q_1864 ENOG4105ZED uncharacterized protein ygaH M3Q_1865 ENOG4108UMN azlc family M3Q_1870 ENOG4105C3G gtp-binding protein M3Q_1871 ENOG4108UMI ABC transporter, permease M3Q_1872 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) M3Q_1873 ENOG4105D01 (LipO)protein M3Q_1876 ENOG4105D01 (LipO)protein M3Q_1879 ENOG4107T8P acyl-Coa dehydrogenase M3Q_1882 ENOG4105EAD ABC transporter M3Q_1883 ENOG4105DRP amino acid AbC transporter M3Q_1884 ENOG4105CDA abc transporter atp-binding protein M3Q_1886 ENOG4105EW9 transcriptional regulator AsnC family M3Q_1889 ENOG41067SE Tetr family transcriptional regulator M3Q_1893 ENOG4105CC0 LysR family Transcriptional regulator M3Q_1895 ENOG4105ETS cytosine purines uracil thiamine allantoin M3Q_1897 ENOG4108IPJ Membrane M3Q_190 ENOG4105DJY efflux transporter, rnd family, mfp subunit M3Q_1902 ENOG4105GQR Chaperone M3Q_1903 ENOG4105X0I Fimbrial M3Q_1907 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) M3Q_1908 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) M3Q_1912 ENOG4108HWY Beta-lactamase M3Q_1917 ENOG4105CV1 Transketolase (EC 2.2.1.1) M3Q_1919 ENOG4108YYC ycei family M3Q_1921 ENOG4108T58 Mg2 transport protein CorA M3Q_1924 ENOG4105YGK Pfam:UPF0157 M3Q_1925 ENOG4105C26 Dehydrogenase M3Q_1926 ENOG4105EW9 transcriptional regulator AsnC family M3Q_1927 ENOG4105CK7 Sodium proline symporter M3Q_1928 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) M3Q_193 ENOG4105C2W permease M3Q_1930 ENOG4108ZX5 transcriptional regulator M3Q_1932 ENOG4105BZ1 (ABC) transporter M3Q_1934 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme M3Q_1935 ENOG4105XPP Protein of unknown function (DUF1275) M3Q_1937 ENOG41080HT Transcriptional regulator, arsr family M3Q_1939 ENOG4105EZE Cupin 4 family protein M3Q_194 ENOG4108W5M transcriptional regulator M3Q_1940 ENOG4108UHJ MAF-like protein M3Q_1944 ENOG4105D2N Aldolase M3Q_1945 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) M3Q_1946 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) M3Q_1947 ENOG4105EHM Aminoglycoside phosphotransferase M3Q_1948 ENOG4108S0S Nucleotidyl transferase M3Q_1950 ENOG4107QJE Chromosome Partitioning Protein M3Q_1951 ENOG4105FA0 parb-like partition protein M3Q_1954 ENOG4105BZ1 (ABC) transporter M3Q_1955 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) M3Q_1957 ENOG4107QRG dna polymerase iii M3Q_1959 ENOG4105F8V Hydrolase, tatD family M3Q_1964 ENOG4108RTD type II secretion system protein K M3Q_1968 ENOG4108Z6B deaminase M3Q_1971 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) M3Q_1972 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) M3Q_1976 ENOG4107RN6 Monooxygenase M3Q_1978 ENOG4105D6Z AFG1 family ATPase M3Q_1979 ENOG4107QP3 malate synthase g M3Q_198 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) M3Q_1981 ENOG4105SG9 biopolymer transport protein, ExbD M3Q_1989 ENOG4105DGW oligopeptidase A M3Q_1991 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component M3Q_1995 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase M3Q_1998 ENOG4105K4T epimerase M3Q_1999 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) M3Q_20 ENOG4108UUM single-stranded DNA-binding protein M3Q_2003 ENOG4108JA2 transcriptioN-repair coupling factor M3Q_2005 ENOG4105F8J Adenylate Guanylate cyclase M3Q_2006 ENOG4108ZIT Ferredoxin, 2FE-2S M3Q_2009 ENOG4108Z4V iron-sulfur cluster assembly M3Q_2010 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins M3Q_2012 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family M3Q_2015 ENOG4105K70 DNA-binding protein M3Q_2016 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) M3Q_2017 ENOG4105E7U AraC family transcriptional regulator M3Q_2018 ENOG4105EEF Alkane 1-monooxygenase M3Q_2019 ENOG4105C1G acyl-Coa dehydrogenase M3Q_2020 ENOG4105C1G acyl-Coa dehydrogenase M3Q_2023 ENOG4108Z66 YbaK ebsC protein M3Q_2027 ENOG4105DUU IucA IucC family protein M3Q_2028 ENOG4105DJU Siderophore biosynthesis protein M3Q_2038 ENOG4108YZT Adenosylcobinamide kinase M3Q_2039 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) M3Q_2043 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) M3Q_2044 ENOG4107TSN permease M3Q_2048 ENOG4105CNM Receptor M3Q_2049 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) M3Q_2052 ENOG4105CJ1 ABC, transporter M3Q_2053 ENOG4107QWP ABC-2 type transporter M3Q_2054 ENOG4107QWP ABC-2 type transporter M3Q_2059 ENOG4105K59 histidine triad (HIT) protein M3Q_2065 ENOG4105F2W methyltransferase M3Q_2067 ENOG4105C28 cystathionine M3Q_2070 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) M3Q_2079 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) M3Q_2080 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) M3Q_2082 ENOG4105BZU Histidine kinase M3Q_2085 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) M3Q_2086 ENOG4107R0V Pyruvate dehydrogenase M3Q_2087 ENOG4105CPP Dehydrogenase, E1 component M3Q_209 ENOG4105CVE Lytic murein transglycosylase M3Q_2090 ENOG4105CHR reductase M3Q_2092 ENOG4105FFC UPF0187 protein M3Q_2094 ENOG4107QPB Beta-lactamase domain protein M3Q_2096 ENOG4108VCT Sulfite exporter TauE/SafE M3Q_2099 ENOG4105UEI Transcriptional Regulator AraC Family M3Q_21 ENOG4107RDB Major Facilitator M3Q_210 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit M3Q_2100 ENOG4105KVH Transcriptional regulator M3Q_2101 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) M3Q_2106 ENOG4106FTQ Taurine ABC transporter, periplasmic M3Q_2107 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component M3Q_211 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) M3Q_2111 ENOG4105CSH Transporter M3Q_2113 ENOG4108IJ0 Aspartate ammonia-lyase M3Q_2116 ENOG4107YNJ LysR family Transcriptional regulator M3Q_2118 ENOG4105CHU acetyl-coa acetyltransferase M3Q_2119 ENOG4105CRW Short chain fatty acid transporter M3Q_2120 ENOG4107QNJ CoA-transferase subunit B M3Q_2122 ENOG4108M0I Transcriptional regulator M3Q_2124 ENOG4105CY2 Citrate transporter M3Q_2125 ENOG4105DTD Dehydrogenase M3Q_2128 ENOG4105CF7 AraC family transcriptional regulator M3Q_2129 ENOG4105D2S major facilitator superfamily M3Q_213 ENOG4105DFU Cell wall formation (By similarity) M3Q_2131 ENOG4105CHR reductase M3Q_2136 ENOG4105F57 Anthranilate dioxygenase reductase M3Q_2137 ENOG4108YS2 small subunit M3Q_2138 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit M3Q_2139 ENOG4105F4R Transcriptional regulator mode M3Q_2140 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein M3Q_2141 ENOG4105E0C molybdate abc transporter M3Q_2142 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) M3Q_2143 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase M3Q_2144 ENOG4105WQI isochorismatase M3Q_2146 ENOG4107T31 5'-nucleotidase M3Q_215 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase M3Q_2152 ENOG4108IGT Dipeptidase M3Q_2156 ENOG4107RZC phospholipase d M3Q_216 ENOG4105DU1 integral membrane protein, terc M3Q_2168 ENOG4105X0I Fimbrial M3Q_2172 ENOG4105CJP fad dependent oxidoreductase M3Q_2176 ENOG4105CT3 Monooxygenase M3Q_2178 ENOG4105ENJ RND efflux system, outer membrane lipoprotein M3Q_2179 ENOG4105BZS acriflavin resistance protein M3Q_218 ENOG4106032 Glutathionylspermidine synthase M3Q_2180 ENOG4105C1P efflux transporter, rnd family, mfp subunit M3Q_2181 ENOG4105CK6 Two component transcriptional regulator (Winged helix family M3Q_2182 ENOG4105E0F Histidine kinase M3Q_2183 ENOG4108821 RND type efflux pump M3Q_2184 ENOG4108R6W Transcriptional regulator, ARAC family M3Q_2187 ENOG4108BAS reductase M3Q_219 ENOG4105BZN citrate synthase M3Q_2198 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) M3Q_220 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) M3Q_2206 ENOG4108UAJ Transcriptional regulator M3Q_222 ENOG4105VG0 50S ribosomal protein l34 M3Q_2221 ENOG4105C5T Phosphoribosyl pyrophosphate synthase M3Q_2225 ENOG4105E0A ABC, transporter M3Q_2226 ENOG4105EHG Permease protein M3Q_2228 ENOG4105DQ4 alcohol dehydrogenase M3Q_2231 ENOG4105CF7 AraC family transcriptional regulator M3Q_2232 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase M3Q_2234 ENOG4105EXW epimerase dehydratase M3Q_2235 ENOG4105DDW LysR family Transcriptional regulator M3Q_2237 ENOG4105C01 Dihydroxy-acid dehydratase M3Q_2238 ENOG4105CZJ Aldehyde dehydrogenase M3Q_2241 ENOG4105CW7 secretion protein, HlyD family M3Q_2245 ENOG4105JSC dimethylmenaquinone methyltransferase M3Q_2246 ENOG4108JQ1 Dehydrogenase M3Q_225 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins M3Q_2251 ENOG4106P55 Transcriptional regulator M3Q_2254 ENOG4105FDP GntR family transcriptional regulator M3Q_2260 ENOG4105CKT filamentous hemagglutinin M3Q_2261 ENOG4105D5K Hemolysin activator protein M3Q_2263 ENOG4105CH2 amidohydrolase M3Q_2265 ENOG4105CKD glutathione-regulated potassium-efflux system protein M3Q_2266 ENOG4105D8V Glucose sorbosone dehydrogenase M3Q_2267 ENOG4105EJC lysr family transcriptional regulator M3Q_2268 ENOG4105CHJ isochorismatase hydrolase M3Q_2270 ENOG4107Z3H Transcriptional regulator, TetR family M3Q_2276 ENOG4105NAE bifunctional deaminase-reductase domain protein M3Q_2278 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase M3Q_2279 ENOG4105K56 Transcriptional regulator M3Q_228 ENOG4105PGM cation diffusion facilitator family transporter M3Q_2283 ENOG4105CH6 catalase M3Q_2286 ENOG4107RGH Aldehyde dehydrogenase M3Q_2289 ENOG41062QD Membrane M3Q_229 ENOG4105T95 Thiol disulfide interChange protein M3Q_2291 ENOG4108JU7 Transcriptional regulator M3Q_2292 ENOG4105CHR reductase M3Q_2293 ENOG4105C1G acyl-Coa dehydrogenase M3Q_2297 ENOG4105CZJ Aldehyde dehydrogenase M3Q_23 ENOG4105DWF phosphomethylpyrimidine kinase M3Q_2301 ENOG4107EJG GntR family transcriptional regulator M3Q_2303 ENOG4108KB2 LysR family Transcriptional regulator M3Q_2304 ENOG4105DTQ mandelate racemase muconate lactonizing M3Q_2305 ENOG4105NN7 muconolactone delta-isomerase M3Q_2307 ENOG4107QP7 CoA-transferase subunit A M3Q_2308 ENOG4107QNJ CoA-transferase subunit B M3Q_2309 ENOG4105CHU acetyl-coa acetyltransferase M3Q_231 ENOG4108UGV hypoxanthine phosphoribosyltransferase M3Q_2310 ENOG4105F2Z 3-oxoadipate enol-lactonase M3Q_2312 ENOG4105C26 Dehydrogenase M3Q_2314 ENOG4105F11 amine oxidase M3Q_2318 ENOG4105CHR reductase M3Q_2320 ENOG4105FUY alpha subunit M3Q_2324 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) M3Q_2326 ENOG4105DNH Major Facilitator M3Q_233 ENOG4107QUY Guanine deaminase M3Q_2331 ENOG4105C1G acyl-Coa dehydrogenase M3Q_2332 ENOG4108PTX LysR family Transcriptional regulator M3Q_2333 ENOG4107HP6 Transcriptional regulator M3Q_2336 ENOG4105MD1 YeeE YedE family protein M3Q_2338 ENOG4105DZG Dehydrogenase M3Q_2339 ENOG4105TW1 Carbohydrate-selective porin OprB M3Q_2340 ENOG4106JPM 3-dehydroshikimate dehydratase M3Q_2341 ENOG4105FF2 Type I DHQase M3Q_2342 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha M3Q_2343 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta M3Q_2344 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase M3Q_2345 ENOG4105D2S major facilitator superfamily M3Q_2346 ENOG4105F2Z 3-oxoadipate enol-lactonase M3Q_2347 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase M3Q_2348 ENOG4105CHU acetyl-coa acetyltransferase M3Q_2349 ENOG4107QNJ CoA-transferase subunit B M3Q_2350 ENOG4107QP7 CoA-transferase subunit A M3Q_2352 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) M3Q_2353 ENOG4107VMU Membrane M3Q_2362 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase M3Q_2365 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) M3Q_2367 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit M3Q_2368 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) M3Q_237 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) M3Q_2374 ENOG4105C7B Threonine dehydratase M3Q_2376 ENOG4105CZN Potassium uptake protein M3Q_2377 ENOG4105HDD phospholipase M3Q_2379 ENOG4105E0K tonB-dependent siderophore receptor M3Q_2382 ENOG4105PV3 Inner membrane protein yqiJ M3Q_2384 ENOG4105C4M (Ubiquinol oxidase) subunit I M3Q_2385 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii M3Q_2389 ENOG41068P6 UPF0319 protein M3Q_239 ENOG4105DQR SNARE associated Golgi M3Q_2391 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) M3Q_2396 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) M3Q_2397 ENOG4105C8Y Acetylornithine aminotransferase M3Q_2398 ENOG4105M2J Glutaredoxin M3Q_24 ENOG4105RA2 Membrane M3Q_240 ENOG4105C5H ABC transporter M3Q_2400 ENOG4105CC0 LysR family Transcriptional regulator M3Q_2401 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) M3Q_2402 ENOG4105CWM branched-chain amino acid transport system II carrier protein M3Q_2407 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) M3Q_2408 ENOG4105DE4 1-phosphofructokinase M3Q_2409 ENOG4105DE4 1-phosphofructokinase M3Q_241 ENOG4108821 RND type efflux pump M3Q_2410 ENOG4105DM4 PTS System M3Q_2415 ENOG4105BZU Histidine kinase M3Q_2417 ENOG4105D8V Glucose sorbosone dehydrogenase M3Q_2418 ENOG4108RAV Conserved protein M3Q_2419 ENOG4105CHH sulfate transporter M3Q_242 ENOG4108821 RND type efflux pump M3Q_2422 ENOG4105C85 amino acid M3Q_2424 ENOG4105F7P transcriptional regulator AsnC family M3Q_2429 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 M3Q_243 ENOG4108821 RND type efflux pump M3Q_2430 ENOG4105VEJ Heat shock protein M3Q_2432 ENOG4105Y3E Modulates RecA activity (By similarity) M3Q_2434 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) M3Q_2439 ENOG4105DZP Membrane-associated zinc metalloprotease M3Q_2441 ENOG4105KNE Phosphatidate cytidylyltransferase M3Q_2442 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) M3Q_2446 ENOG4105CUX Signal transduction histidine kinase M3Q_2447 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family M3Q_245 ENOG4105D74 hydrolase M3Q_2458 ENOG4105CMR udp-glucose 4-epimerase M3Q_2459 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) M3Q_246 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) M3Q_2463 ENOG4105T38 integral membrane protein M3Q_2464 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family M3Q_2466 ENOG4105CVM Molybdenum cofactor synthesis domain protein M3Q_2467 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) M3Q_247 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) M3Q_2470 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) M3Q_2474 ENOG4108IFG nitrite reductase, (NAD(P)H) M3Q_2475 ENOG4107QZF nitrite reductase NADPH large subunit M3Q_2476 ENOG4107QZF nitrite reductase NADPH large subunit M3Q_2478 ENOG4105CK6 Two component transcriptional regulator (Winged helix family M3Q_2482 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein M3Q_2483 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase M3Q_2485 ENOG4105D8G Major Facilitator superfamily M3Q_2489 ENOG4105CBC glutamate synthase M3Q_2495 ENOG4105C0A alcohol dehydrogenase M3Q_2497 ENOG4105HSS phospholipase C M3Q_2499 ENOG4107QMP dna polymerase iii subunits gamma and tau M3Q_250 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase M3Q_2504 ENOG4105CHR reductase M3Q_2505 ENOG4105CHU acetyl-coa acetyltransferase M3Q_2507 ENOG4105C5Q Transcriptional regulator M3Q_2508 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) M3Q_2509 ENOG4108NIW Leucine export protein LeuE M3Q_2510 ENOG4105EW9 transcriptional regulator AsnC family M3Q_2511 ENOG4105DKK Benzoate M3Q_2513 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic M3Q_2518 ENOG41081QV Universal stress protein M3Q_2519 ENOG4105C5H ABC transporter M3Q_252 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) M3Q_2523 ENOG4105CNM Receptor M3Q_253 ENOG4105DTN riboflavin biosynthesis protein ribF M3Q_2531 ENOG4105CUY Mechanosensitive ion channel M3Q_2533 ENOG4105R8C Transcriptional regulator M3Q_2535 ENOG4105EW9 transcriptional regulator AsnC family M3Q_2536 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) M3Q_2538 ENOG4105EMU Dehydrogenase M3Q_2540 ENOG4105CD8 aminopeptidase N M3Q_2544 ENOG4105F4I Transcriptional regulator M3Q_2546 ENOG4107QUV Domain protein M3Q_2547 ENOG4105C0A alcohol dehydrogenase M3Q_2549 ENOG4107RR1 TRANSCRIPTIONal M3Q_255 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) M3Q_2551 ENOG4107R55 ethanolamine transporter M3Q_2552 ENOG4105CPD ethanolamine ammonia-lyase M3Q_2553 ENOG4107FQ9 ethanolamine ammonia-lyase M3Q_2554 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) M3Q_2559 ENOG4108RCM Nitroreductase M3Q_256 ENOG4108R86 Transcriptional regulator M3Q_2560 ENOG4108TZV Membrane M3Q_2561 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) M3Q_2563 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) M3Q_2564 ENOG4105K8N protein family UPF0079, ATPase M3Q_257 ENOG4108VM9 ABC, transporter M3Q_2571 ENOG4105DZ2 Transcriptional regulator M3Q_2574 ENOG4105F27 Major Facilitator M3Q_2575 ENOG4105EYW Ion transport protein M3Q_2577 ENOG4107QIJ Aconitate hydratase 2 M3Q_258 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component M3Q_2580 ENOG4105CFU surface antigen M3Q_2581 ENOG4107S74 Lysophospholipid transporter LplT M3Q_2584 ENOG4105CFQ glutamine synthetase M3Q_2585 ENOG4105EEX Two component transcriptional regulator (Winged helix family M3Q_2586 ENOG4105C08 Histidine kinase M3Q_2588 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) M3Q_2589 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) M3Q_259 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) M3Q_2593 ENOG4105D06 uba thif-type nad fad binding protein M3Q_2594 ENOG4108MEJ flavin reductase domain protein M3Q_2596 ENOG4105C1G acyl-Coa dehydrogenase M3Q_2599 ENOG4105GVF (ABC) transporter M3Q_26 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein M3Q_260 ENOG4105GVF (ABC) transporter M3Q_2600 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component M3Q_2601 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) M3Q_2604 ENOG4105CC0 LysR family Transcriptional regulator M3Q_2607 ENOG4105DEN Luciferase family M3Q_2609 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD M3Q_261 ENOG4105GVF (ABC) transporter M3Q_2610 ENOG4105CND Glycosyl transferase, family 2 M3Q_2611 ENOG4107BJW polysaccharide deacetylase M3Q_2616 ENOG4105E2S oxidase) subunit II M3Q_2617 ENOG4105BZ9 Cytochrome C oxidase, subunit I M3Q_2618 ENOG4105CCU oxidase (Subunit III) M3Q_2619 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) M3Q_262 ENOG4107QZM n-acetylglutamate synthase M3Q_2624 ENOG4105CDU Replicative dna helicase M3Q_2625 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) M3Q_2635 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) M3Q_2636 ENOG4105DC1 bifunctional purine biosynthesis protein purh M3Q_2637 ENOG4105C12 Phosphoribosylglycinamide synthetase M3Q_2639 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) M3Q_2640 ENOG4108UMI ABC transporter, permease M3Q_2641 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) M3Q_2643 ENOG4105CK2 sodium dicarboxylate symporter M3Q_265 ENOG4105UBK short-chain dehydrogenase reductase M3Q_266 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) M3Q_2673 ENOG4105DY2 Paraquat-inducible protein b M3Q_2674 ENOG4105F1S paraquat-inducible protein a M3Q_2677 ENOG4105CEB Aspartate aminotransferase M3Q_2680 ENOG4105CSH Transporter M3Q_269 ENOG41062JF Transcriptional regulator M3Q_2690 ENOG4105JXH GntR family transcriptional regulator M3Q_2692 ENOG4105D6U Sodium Glutamate Symporter M3Q_2698 ENOG4105H4F exported protein M3Q_27 ENOG4108WUH Transcriptional regulator, TetR family M3Q_2705 ENOG4105C26 Dehydrogenase M3Q_2706 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) M3Q_2707 ENOG4105EVZ LysR family transcriptional regulator M3Q_2708 ENOG4105D9P serine threonine protein kinase M3Q_2713 ENOG4105VCC 30S ribosomal protein S21 M3Q_2714 ENOG4105KTH gatB Yqey M3Q_2715 ENOG4105ERG peptidase m48, ste24p M3Q_2716 ENOG4105C5I Dehydrogenase M3Q_2719 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase M3Q_2726 ENOG41069NU Nitroreductase M3Q_2728 ENOG4105C1J atp-dependent rna helicase M3Q_2729 ENOG4105VEQ Cold shock protein M3Q_2731 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) M3Q_2732 ENOG4105M08 Membrane M3Q_2738 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) M3Q_2739 ENOG4105CIN aminoacyl-histidine dipeptidase M3Q_274 ENOG4105HSS phospholipase C M3Q_2741 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase M3Q_2742 ENOG4105CQC Prephenate dehydratase M3Q_2743 ENOG4105NIV Esterase M3Q_2744 ENOG4105C1G acyl-Coa dehydrogenase M3Q_2745 ENOG4105CK2 sodium dicarboxylate symporter M3Q_2746 ENOG4107QYG anthranilate phosphoribosyltransferase M3Q_2747 ENOG4105VUT cytoplasmic protein M3Q_2748 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) M3Q_2749 ENOG4105BZ4 penicillin-binding protein M3Q_2751 ENOG4105M6F mutator MutT protein M3Q_2753 ENOG4105DHQ Histidine kinase M3Q_2754 ENOG4105XJC Two component transcriptional regulator (Winged helix family M3Q_2756 ENOG4107QHF type ii secretion system protein e M3Q_2758 ENOG4108R96 Methyltransferase, YaeB family M3Q_2759 ENOG4105DP0 ferredoxin-NADP reductase M3Q_276 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase M3Q_2760 ENOG4105JAB phenazine biosynthesis protein, phzf family M3Q_2761 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family M3Q_2762 ENOG4105CFP Peptidase U32 M3Q_2763 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding M3Q_2765 ENOG4108JEH abc transporter atp-binding protein M3Q_2766 ENOG4106YG3 ABC transporter M3Q_2767 ENOG4105DSP amino acid AbC transporter M3Q_2768 ENOG4105E89 ABC transporter M3Q_277 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase M3Q_2770 ENOG4105ENT Efflux transporter rnd family, mfp subunit M3Q_2772 ENOG4105ENJ RND efflux system, outer membrane lipoprotein M3Q_2778 ENOG4105DA5 (ABC) transporter M3Q_2779 ENOG4105E3A (ABC) transporter M3Q_278 ENOG4105CJR Integral membrane protein (MviN M3Q_2782 ENOG4105CNI cell division protein FtsW M3Q_2783 ENOG4105CVE Lytic murein transglycosylase M3Q_279 ENOG4108V1T peptidylprolyl cis-trans isomerase M3Q_2791 ENOG4105CE9 30S ribosomal protein S2 M3Q_2792 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) M3Q_2794 ENOG4107RNU major facilitator superfamily MFS_1 M3Q_2797 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) M3Q_2798 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) M3Q_2799 ENOG4107QPN acyl-Coa dehydrogenase M3Q_28 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) M3Q_280 ENOG4108V1T peptidylprolyl cis-trans isomerase M3Q_2802 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) M3Q_2803 ENOG4105SYT Methylenetetrahydrofolate reductase M3Q_2804 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) M3Q_2805 ENOG4105BZU Histidine kinase M3Q_2806 ENOG4105C6K Malic enzyme M3Q_2808 ENOG4105C0H protease M3Q_2809 ENOG4107QNR UPF0135 protein M3Q_281 ENOG4105D75 Capsular exopolysaccharide family M3Q_2810 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) M3Q_2814 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) M3Q_2816 ENOG4105C5F glutamine synthetase M3Q_2817 ENOG4105DUX Transporter M3Q_2819 ENOG4105DDQ anthranilate synthase M3Q_2820 ENOG4105CD8 aminopeptidase N M3Q_2826 ENOG4105C7W Xanthine dehydrogenase M3Q_2828 ENOG4105EUJ GTP cyclohydrolase i M3Q_283 ENOG4105DAY polysaccharide export protein M3Q_2834 ENOG4105NX3 Membrane M3Q_2837 ENOG4105E4F Isochorismate synthase M3Q_284 ENOG4107QQG Dehydrogenase M3Q_2841 ENOG4105BZ1 (ABC) transporter M3Q_2844 ENOG4105WQI isochorismatase M3Q_2845 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase M3Q_2846 ENOG4105C0W non-ribosomal peptide synthetase M3Q_2850 ENOG4108IPW abc transporter atp-binding protein M3Q_2855 ENOG4105CEY Amp-dependent synthetase and ligase M3Q_2858 ENOG4105WWK YheO domain protein M3Q_286 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) M3Q_2861 ENOG4105C2I pirin domain protein M3Q_2864 ENOG4105J7D transcriptional regulator M3Q_2866 ENOG4107WEA mandelate racemase muconate lactonizing M3Q_2867 ENOG4107QNK )-transporter M3Q_2868 ENOG41060M8 Pfam:PhdYeFM M3Q_2874 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) M3Q_2875 ENOG4107QZF nitrite reductase NADPH large subunit M3Q_2876 ENOG4105C26 Dehydrogenase M3Q_2878 ENOG4105C94 Transporter M3Q_2879 ENOG4105C94 Transporter M3Q_2880 ENOG4105ETT transcriptional Regulator, LysR family M3Q_2881 ENOG4105C85 amino acid M3Q_2882 ENOG4105C26 Dehydrogenase M3Q_2885 ENOG4108K8K Transcriptional regulator M3Q_289 ENOG4108F01 MaoC domain protein M3Q_2891 ENOG4105VCD cytoplasmic protein M3Q_2892 ENOG4105D22 carbon starvation protein M3Q_2894 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein M3Q_2910 ENOG4105EFC phage portal protein HK97 family M3Q_2911 ENOG4105CAR Terminase, large subunit M3Q_292 ENOG4105K64 Glycosyl transferase, family 2 M3Q_293 ENOG4107STW synthase M3Q_2931 ENOG4105VCD cytoplasmic protein M3Q_2932 ENOG4105D22 carbon starvation protein M3Q_2934 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein M3Q_2938 ENOG4105DHU Bile acid M3Q_2941 ENOG4105DAN ATP-dependent protease M3Q_2942 ENOG4105EJC lysr family transcriptional regulator M3Q_2943 ENOG4108K5P (LipO)protein M3Q_2947 ENOG4105DZ1 carboxypeptidase M3Q_2948 ENOG4108Z0R Transferase M3Q_295 ENOG4105CG5 Glycosyl transferase (Group 1 M3Q_2952 ENOG4107QTF adenylosuccinate lyase M3Q_2955 ENOG4105ERU peptidase M3Q_2956 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) M3Q_2958 ENOG4105C8U phosphate abc transporter M3Q_2959 ENOG4105CVA phosphate M3Q_296 ENOG4108RYC glycosyltransferase M3Q_2960 ENOG4105C85 amino acid M3Q_2961 ENOG4107RA9 decarboxylase M3Q_2962 ENOG4105F7P transcriptional regulator AsnC family M3Q_2964 ENOG4105DY8 decarboxylase M3Q_2965 ENOG4108JPW Aminotransferase M3Q_297 ENOG4105D3Q Sugar transferase M3Q_2970 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) M3Q_2974 ENOG4105D3G Pseudouridine synthase M3Q_2977 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) M3Q_298 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase M3Q_2983 ENOG4105JAB phenazine biosynthesis protein, phzf family M3Q_2984 ENOG4108ETY sodium dicarboxylate symporter M3Q_2985 ENOG4105EGI Transcriptional regulator M3Q_2986 ENOG4105CBP Major Facilitator M3Q_299 ENOG4105C6Y Udp-glucose 6-dehydrogenase M3Q_2990 ENOG4108R99 pseudouridine synthase M3Q_2991 ENOG4105E9K Isocitrate dehydrogenase M3Q_2993 ENOG4105DZ1 carboxypeptidase M3Q_2994 ENOG4105CEP NADH dehydrogenase M3Q_2995 ENOG4108YZY peptidylprolyl cis-trans isomerase M3Q_2996 ENOG4105CVP deoxyribo-dipyrimidine photolyase M3Q_2999 ENOG4107R8N Glycosyl transferase, family 2 M3Q_30 ENOG4105BZU Histidine kinase M3Q_3005 ENOG4105EA8 2-Nitropropane dioxygenase M3Q_3006 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) M3Q_3007 ENOG4107QS8 (LipO)protein M3Q_301 ENOG4105CMR udp-glucose 4-epimerase M3Q_3014 ENOG4105DTR rard protein M3Q_3016 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) M3Q_3018 ENOG4105BZU Histidine kinase M3Q_3020 ENOG4105CHM Aminotransferase M3Q_3024 ENOG4105EMU Dehydrogenase M3Q_3025 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase M3Q_3026 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) M3Q_3027 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) M3Q_3029 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) M3Q_303 ENOG4107QKV phosphomannomutase M3Q_3032 ENOG4105C3F Signal peptidase i M3Q_3035 ENOG4105C0H protease M3Q_3036 ENOG4108IYU L-aspartate oxidase M3Q_3039 ENOG4105HHA aminodeoxychorismate lyase M3Q_304 ENOG4105DAA L-lactate M3Q_3040 ENOG4105YAZ 4-amino-4-deoxychorismate lyase M3Q_3041 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein M3Q_3043 ENOG4108I5D sulfate abc transporter M3Q_3045 ENOG4108IJ6 ABC transporter M3Q_3046 ENOG4107R11 Transcriptional regulator M3Q_3049 ENOG4107VRB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) M3Q_305 ENOG41073TP transcriptional regulator M3Q_3050 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) M3Q_3053 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen M3Q_3056 ENOG4108UKI Enoyl-CoA hydratase M3Q_3057 ENOG4105EGD dinuclear metal center protein, YbgI family M3Q_3059 ENOG4105C2C drug resistance transporter, Bcr CflA M3Q_3060 ENOG4108ETH Formylglycinamide ribotide synthetase M3Q_3064 ENOG4105CH2 amidohydrolase M3Q_3065 ENOG4107YD3 Thioesterase M3Q_3066 ENOG4105E02 MotA TolQ exbB proton channel M3Q_3067 ENOG4105M8F Biopolymer transport protein exbD tolR M3Q_3069 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) M3Q_307 ENOG4105CXG d-lactate dehydrogenase M3Q_3070 ENOG4105KCK Peptidoglycan-associated lipoprotein M3Q_308 ENOG4105CGF Aromatic amino acid aminotransferase M3Q_3080 ENOG4105C02 permease M3Q_3082 ENOG4108V3E phosphoribosylglycinamide formyltransferase M3Q_3083 ENOG4107R6F Alpha Beta Hydrolase Fold protein M3Q_3084 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) M3Q_3086 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 M3Q_3087 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) M3Q_3088 ENOG4105D60 lipoprotein releasing system transmembrane protein M3Q_309 ENOG4105DRR Transcriptional regulator, GntR family M3Q_3095 ENOG4107KET secretion protein, HlyD family M3Q_310 ENOG4105CR4 methylisocitrate lyase M3Q_3102 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) M3Q_3103 ENOG4105C10 Electron transfer flavoprotein M3Q_3104 ENOG4105BZJ Electron transfer flavoprotein M3Q_3105 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) M3Q_3106 ENOG4105N14 lysine exporter protein LysE YggA M3Q_3108 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) M3Q_311 ENOG4105BZN citrate synthase M3Q_3110 ENOG4105C85 amino acid M3Q_3111 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) M3Q_3113 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) M3Q_3116 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) M3Q_3117 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit M3Q_3118 ENOG4105BZW Glycerate kinase M3Q_312 ENOG4108I0Z Aconitate hydratase M3Q_3126 ENOG4105CEY Amp-dependent synthetase and ligase M3Q_3128 ENOG4108RRZ Transcription elongation factor GreB M3Q_3132 ENOG4105E4C Lytic transglycosylase catalytic M3Q_3135 ENOG4105BZS acriflavin resistance protein M3Q_3136 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase M3Q_3138 ENOG41080IJ Diacylglycerol kinase M3Q_3142 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) M3Q_3145 ENOG4105C6V Glycerol-3-phosphate dehydrogenase M3Q_3146 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) M3Q_3147 ENOG4105CSH Transporter M3Q_3154 ENOG4105EEI dihydropteroate synthase M3Q_3155 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) M3Q_3157 ENOG4105HBR Rna-binding protein M3Q_3160 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain M3Q_3161 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain M3Q_3164 ENOG41080TK Universal stress protein M3Q_3167 ENOG4105PNM synthesis protein M3Q_3173 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) M3Q_3180 ENOG4105EEQ Na H antiporter M3Q_3181 ENOG4105CGZ zinc metallopeptidase M3Q_3182 ENOG4105CKW Inner membrane protein yedI M3Q_3184 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha M3Q_3186 ENOG4107QN2 dihydrolipoyl dehydrogenase M3Q_3187 ENOG4105C7S Dehydrogenase M3Q_3188 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 M3Q_3189 ENOG4105E33 succinate dehydrogenase M3Q_3191 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein M3Q_3192 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit M3Q_3199 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) M3Q_32 ENOG4105C94 Transporter M3Q_320 ENOG4108IG5 Transcriptional regulator M3Q_3200 ENOG41084BA UPF0250 protein M3Q_3201 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) M3Q_3204 ENOG4105CUB amino acid M3Q_3206 ENOG4105KVH Transcriptional regulator M3Q_3207 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) M3Q_3208 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) M3Q_3211 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) M3Q_3216 ENOG410841Q phosphoesterase PA-phosphatase related protein M3Q_3217 ENOG4105C1P efflux transporter, rnd family, mfp subunit M3Q_3218 ENOG4105BZS acriflavin resistance protein M3Q_3219 ENOG4105ENJ RND efflux system, outer membrane lipoprotein M3Q_3220 ENOG4105K8R UPF0145 protein M3Q_3221 ENOG4105K8R UPF0145 protein M3Q_3225 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) M3Q_3229 ENOG4108M0I Transcriptional regulator M3Q_323 ENOG4105D3G Pseudouridine synthase M3Q_3232 ENOG4105DHQ Histidine kinase M3Q_3233 ENOG4105XJC Two component transcriptional regulator (Winged helix family M3Q_3234 ENOG4105DIJ Phosphoethanolamine transferase M3Q_3238 ENOG4105D78 K07001 NTE family protein M3Q_3241 ENOG4105MSB protein, conserved in bacteria M3Q_3242 ENOG4105CTB Polyprenyl synthetase M3Q_3243 ENOG4105C7F AcnD-accessory protein PrpF M3Q_3244 ENOG4105C85 amino acid M3Q_3247 ENOG4105CF7 AraC family transcriptional regulator M3Q_3252 ENOG4108X0B nad(p)h dehydrogenase (quinone) M3Q_3254 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein M3Q_3256 ENOG4105D8T Acyltransferase M3Q_3258 ENOG4105C03 ribonuclease M3Q_3259 ENOG4108Z03 MAF-like protein M3Q_3260 ENOG4105VQ7 Rod shape-determining protein MreD M3Q_3261 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) M3Q_3262 ENOG4105DFF Rod shape-determining protein mreb M3Q_3263 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) M3Q_3265 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) M3Q_3272 ENOG4105C7B Threonine dehydratase M3Q_3273 ENOG4105D78 K07001 NTE family protein M3Q_3274 ENOG4105BZG amino acid carrier protein M3Q_3277 ENOG4105C2C drug resistance transporter, Bcr CflA M3Q_3278 ENOG4105EM2 membrane M3Q_328 ENOG4105EW9 transcriptional regulator AsnC family M3Q_3280 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) M3Q_3282 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein M3Q_3283 ENOG4105WD1 Membrane M3Q_3285 ENOG4106HKS Entericidin EcnA/B family M3Q_3288 ENOG4105CBS Chea signal transduction histidine kinase M3Q_3289 ENOG4105C8Q Methyl-accepting chemotaxis M3Q_3290 ENOG4108ZGA chew protein M3Q_3291 ENOG4105M3Z response regulator M3Q_3292 ENOG4108UNF response regulator M3Q_3297 ENOG4105KWI UPF0339 protein M3Q_3298 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA M3Q_3299 ENOG4105K78 MarR family Transcriptional regulator M3Q_3301 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) M3Q_3302 ENOG4105T95 Thiol disulfide interChange protein M3Q_3305 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase M3Q_3306 ENOG4105CHB tonB-dependent Receptor M3Q_3308 ENOG4105CGZ zinc metallopeptidase M3Q_3309 ENOG4105CKW Inner membrane protein yedI M3Q_331 ENOG4105M4H endoribonuclease L-psp M3Q_3311 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha M3Q_3313 ENOG4107QN2 dihydrolipoyl dehydrogenase M3Q_3314 ENOG4105C7S Dehydrogenase M3Q_3316 ENOG4108VX5 3-methyladenine DNA glycosylase M3Q_3318 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) M3Q_332 ENOG4105C85 amino acid M3Q_3322 ENOG4105C2W permease M3Q_3324 ENOG4108IQI permease M3Q_3325 ENOG4105E0Y RtcB Protein M3Q_3327 ENOG4108WHA ompa motb domain protein M3Q_3329 ENOG4105CHU acetyl-coa acetyltransferase M3Q_333 ENOG4105C85 amino acid M3Q_3331 ENOG410814C multidrug resistance protein M3Q_3333 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) M3Q_3334 ENOG4105DZG Dehydrogenase M3Q_3335 ENOG4105TW1 Carbohydrate-selective porin OprB M3Q_3337 ENOG4108R6W Transcriptional regulator, ARAC family M3Q_3338 ENOG4105CHU acetyl-coa acetyltransferase M3Q_3345 ENOG4108UT2 hemolysin iii M3Q_3346 ENOG4105CSH Transporter M3Q_3349 ENOG4105D3R alkyl hydroperoxide reductase M3Q_335 ENOG4105C26 Dehydrogenase M3Q_3353 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase M3Q_336 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase M3Q_3360 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) M3Q_3363 ENOG4108WBT adenosyltransferase M3Q_3367 ENOG4105CNG UPF0061 protein M3Q_3368 ENOG4105E3W Two component transcriptional regulator (Winged helix family M3Q_3369 ENOG4105EB3 Histidine kinase M3Q_3371 ENOG4105CSU acyl-Coa dehydrogenase M3Q_3372 ENOG4105CSU acyl-Coa dehydrogenase M3Q_3373 ENOG4108R4R Iron-regulated virulence regulatory protein M3Q_3374 ENOG4108K3A Glutathione S-transferase M3Q_3375 ENOG4108VY7 phosphate-starvation-inducible protein PsiE M3Q_3379 ENOG4105UGU tonB-dependent Receptor M3Q_338 ENOG4105C1G acyl-Coa dehydrogenase M3Q_3387 ENOG4108PQP glycosyl transferase group 1 M3Q_3389 ENOG4107BJW polysaccharide deacetylase M3Q_339 ENOG4105E39 Enoyl-CoA hydratase M3Q_3392 ENOG4105CM2 brancheD-chain amino acid aminotransferase M3Q_3393 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) M3Q_3394 ENOG4105BZU Histidine kinase M3Q_3399 ENOG4105VIE preprotein translocase, subunit YajC M3Q_34 ENOG4107QN1 sodium solute M3Q_340 ENOG4105E39 Enoyl-CoA hydratase M3Q_3400 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) M3Q_3401 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) M3Q_3402 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase M3Q_3404 ENOG4105FFC UPF0187 protein M3Q_3405 ENOG4105DB7 PHP domain protein M3Q_3407 ENOG4105K9H YciI-like protein M3Q_341 ENOG4105CSH Transporter M3Q_3413 ENOG4105NAU thioesterase Superfamily protein M3Q_3415 ENOG4107U2T alpha beta M3Q_3416 ENOG4107QPB Beta-lactamase domain protein M3Q_3418 ENOG4107QN2 dihydrolipoyl dehydrogenase M3Q_3420 ENOG4108KHX Diguanylate cyclase M3Q_3421 ENOG4105UYK outer membrane protein a M3Q_3423 ENOG4107RZC phospholipase d M3Q_3425 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) M3Q_3429 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) M3Q_3430 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) M3Q_3433 ENOG4108UJD 30S ribosomal protein S9 M3Q_3434 ENOG4107MKT Stringent starvation protein a M3Q_3435 ENOG4105KB2 stringent starvation protein b M3Q_3439 ENOG4105C1G acyl-Coa dehydrogenase M3Q_3440 ENOG4107QX3 carboxylase M3Q_3443 ENOG4108RZE Tetr family transcriptional regulator M3Q_3444 ENOG4105C1G acyl-Coa dehydrogenase M3Q_3448 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase M3Q_3449 ENOG4105D6S protein involved in catabolism of external DNA M3Q_3455 ENOG4105E4C Lytic transglycosylase catalytic M3Q_3457 ENOG4105C9A Phoh family M3Q_346 ENOG4105C1G acyl-Coa dehydrogenase M3Q_3463 ENOG4105CS1 NAD(P)H quinone oxidoreductase M3Q_3464 ENOG4107S2Z UPF0761 membrane protein M3Q_3466 ENOG4108K2B transcriptional regulator M3Q_3467 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase M3Q_3472 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) M3Q_3473 ENOG4105DGW oligopeptidase A M3Q_3474 ENOG4105VKU nucleicacid-binding protein M3Q_3482 ENOG4105C1G acyl-Coa dehydrogenase M3Q_3487 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) M3Q_3489 ENOG41067V7 50S ribosomal protein L36 M3Q_349 ENOG4105CEY Amp-dependent synthetase and ligase M3Q_3490 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) M3Q_35 ENOG41062QD Membrane M3Q_3509 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) M3Q_3512 ENOG41089BK Glutamine amido-transferase M3Q_3513 ENOG4105C28 cystathionine M3Q_3514 ENOG4105D7A ATP-binding protein M3Q_3516 ENOG4105KPV Transcriptional regulator M3Q_3519 ENOG4105CK2 sodium dicarboxylate symporter M3Q_352 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) M3Q_3520 ENOG4105C29 acyl-CoA thioesterase M3Q_3524 ENOG4105CB5 ATP-dependent DNA helicase recG M3Q_3525 ENOG4105MJ2 Competence protein M3Q_3527 ENOG4108URH decarboxylase M3Q_3528 ENOG4105D7N magnesium and cobalt transport protein CorA M3Q_3530 ENOG4105E3I toluene tolerance M3Q_3532 ENOG4105CY3 ABC transporter, permease M3Q_3533 ENOG4105DHJ ABC, transporter M3Q_3534 ENOG4105C1J atp-dependent rna helicase M3Q_3535 ENOG4105ECY inositol monophosphatase M3Q_3538 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) M3Q_354 ENOG4107PSF BolA-like protein M3Q_3541 ENOG4105CSU acyl-Coa dehydrogenase M3Q_3543 ENOG41067S9 phage shock protein C, PspC M3Q_3544 ENOG4105W87 Cbs domain M3Q_3556 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin M3Q_3561 ENOG4105C26 Dehydrogenase M3Q_3563 ENOG4105C8Y Acetylornithine aminotransferase M3Q_3564 ENOG4105D82 Glutamate dehydrogenase M3Q_3565 ENOG4108IQI permease M3Q_357 ENOG4106MP8 UPF0754 membrane protein M3Q_357 ENOG4106MP8 UPF0754 membrane protein M3Q_3572 ENOG4105IPI Membrane M3Q_3573 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) M3Q_3574 ENOG4105EM2 membrane M3Q_3575 ENOG4107QF7 multi-drug M3Q_3577 ENOG4105NF4 modulator of drug activity M3Q_3578 ENOG4105VRH Antibiotic biosynthesis monooxygenase M3Q_358 ENOG4108VBZ doxx family M3Q_3580 ENOG4105CQB FAD linked oxidase domain protein M3Q_3581 ENOG4108JQ1 Dehydrogenase M3Q_3586 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) M3Q_3587 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) M3Q_3588 ENOG4107IFA Lipase (EC 3.1.1.3) M3Q_359 ENOG4105DQR SNARE associated Golgi M3Q_3591 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) M3Q_36 ENOG4105BZU Histidine kinase M3Q_3601 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) M3Q_3603 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) M3Q_3604 ENOG4105KME endoribonuclease L-psp M3Q_3606 ENOG4108UQY Iron-storage protein M3Q_3607 ENOG4108YSG O-Antigen polymerase M3Q_3611 ENOG4105HA9 of methanol dehydrogenase type M3Q_3612 ENOG4108V0P LemA family M3Q_3614 ENOG4105BZ8 glutamate synthase M3Q_3615 ENOG4105CBC glutamate synthase M3Q_3619 ENOG4105E4G Type IV pilus M3Q_362 ENOG4107QJE Chromosome Partitioning Protein M3Q_3624 ENOG4108JQC penicillin-binding protein 1A M3Q_3625 ENOG4105DHI Methyltransferase M3Q_3628 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) M3Q_3629 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) M3Q_3630 ENOG4105CJN penicillin-binding protein M3Q_3633 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein M3Q_3636 ENOG4108IQI permease M3Q_364 ENOG4107PSF BolA-like protein M3Q_3650 ENOG4105C5H ABC transporter M3Q_3652 ENOG4105PDP Short chain dehydrogenase M3Q_3653 ENOG4105CHH sulfate transporter M3Q_3654 ENOG4105BZM domain protein M3Q_3657 ENOG4105C5H ABC transporter M3Q_3659 ENOG4105PDP Short chain dehydrogenase M3Q_366 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) M3Q_3660 ENOG4105CHH sulfate transporter M3Q_3662 ENOG4105DPZ Two component transcriptional regulator (Winged helix family M3Q_3663 ENOG4105E0F Histidine kinase M3Q_3664 ENOG4105CYC Transferase M3Q_3668 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) M3Q_3674 ENOG41061CK Antibiotic biosynthesis monooxygenase M3Q_3677 ENOG4105CUV Homoserine Kinase M3Q_3689 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein M3Q_369 ENOG4105CEY Amp-dependent synthetase and ligase M3Q_3690 ENOG4105KVH Transcriptional regulator M3Q_3695 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) M3Q_3696 ENOG4105CPC Aldo Keto reductase M3Q_371 ENOG4105FAV ABC, transporter M3Q_372 ENOG4105FDK ABC transporter M3Q_377 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) M3Q_385 ENOG4108V06 Glutathione peroxidase M3Q_387 ENOG4107RTG Major Facilitator superfamily M3Q_388 ENOG4108IND Tetr family transcriptional regulator M3Q_39 ENOG4108UZX fmn reductase M3Q_391 ENOG4105C79 DNA protecting protein DprA M3Q_398 ENOG4105Y7M Transcriptional regulator, TetR family M3Q_4 ENOG4106NZI LysR family Transcriptional regulator M3Q_40 ENOG4105FBW Monooxygenase M3Q_400 ENOG4105CV8 reductase M3Q_401 ENOG4105HEI LysR family (Transcriptional regulator M3Q_404 ENOG4105DQ4 alcohol dehydrogenase M3Q_405 ENOG4108R3E Dna-3-methyladenine glycosylase i M3Q_408 ENOG4105CEN a g-specific adenine glycosylase M3Q_41 ENOG4105D5G Transposase M3Q_412 ENOG4108ZZ3 UPF0260 protein M3Q_414 ENOG4105D1H recombination factor protein RarA M3Q_415 ENOG4105S64 Formate nitrite transporter M3Q_419 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) M3Q_420 ENOG4108RWI nicotinamidase M3Q_421 ENOG4105C09 Bile acid M3Q_422 ENOG4107QI1 Mate efflux family protein M3Q_423 ENOG4105EWC Purine nucleoside phosphorylase M3Q_427 ENOG4108RXX maleylacetoacetate isomerase M3Q_43 ENOG4108W2Y isochorismatase M3Q_430 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) M3Q_431 ENOG4105CEY Amp-dependent synthetase and ligase M3Q_434 ENOG4105F0N pyrophosphate phospho-hydrolase M3Q_435 ENOG4105EPF Outer membrane porin M3Q_438 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) M3Q_44 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) M3Q_440 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family M3Q_441 ENOG4105C0P Mg chelatase subunit ChlI M3Q_448 ENOG4105CHH sulfate transporter M3Q_454 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) M3Q_46 ENOG4105D64 Mechanosensitive ion channel M3Q_465 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) M3Q_474 ENOG4105CHH sulfate transporter M3Q_48 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase M3Q_482 ENOG4108R0M Aminoglycoside M3Q_484 ENOG4105C0P Mg chelatase subunit ChlI M3Q_487 ENOG4105BZU Histidine kinase M3Q_489 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) M3Q_49 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase M3Q_497 ENOG4108K5H permease YjgP YjgQ family protein M3Q_498 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) M3Q_499 ENOG4105CN1 protease M3Q_5 ENOG4105D94 Major Facilitator Superfamily M3Q_500 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family M3Q_501 ENOG4107TUY Histidine kinase M3Q_503 ENOG41061WM D-Alanyl-D-Alanine M3Q_505 ENOG4105D6E homoserine dehydrogenase M3Q_506 ENOG4105T95 Thiol disulfide interChange protein M3Q_507 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) M3Q_509 ENOG4105CE1 Ferrous iron transport protein b M3Q_512 ENOG4105CNI cell division protein FtsW M3Q_513 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) M3Q_514 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters M3Q_515 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) M3Q_52 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) M3Q_520 ENOG4108RNG Permease of the drug metabolite transporter M3Q_521 ENOG4105DFG type I secretion outer membrane protein M3Q_522 ENOG4108UTW Plays a role in the regulation of phosphate uptake M3Q_525 ENOG4108HRK Histidine kinase M3Q_526 ENOG4108NEV two component transcriptional regulator, LytTR family M3Q_527 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) M3Q_532 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS M3Q_535 ENOG4105GVR general secretion pathway protein D M3Q_536 ENOG4105TV9 FHA Domain-Containing protein M3Q_537 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) M3Q_54 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) M3Q_541 ENOG4105PM1 preprotein translocase subunit SecE M3Q_542 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) M3Q_552 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) M3Q_553 ENOG4105D3Y Na H antiporter M3Q_556 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) M3Q_559 ENOG4107ZXU DSBA oxidoreductase M3Q_57 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) M3Q_572 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase M3Q_573 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) M3Q_579 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) M3Q_581 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) M3Q_584 ENOG4105C2N RNA methyltransferase TrmH family group 3 M3Q_586 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) M3Q_589 ENOG4107QHF type ii secretion system protein e M3Q_591 ENOG4107EJC Preprotein translocase subunit SecG M3Q_593 ENOG4105CHV Transcription elongation factor NusA M3Q_596 ENOG4105KJM monovalent cation h antiporter subunit g M3Q_597 ENOG4105W4C monovalent cation H antiporter subunit F M3Q_598 ENOG4105SC1 monovalent cation H antiporter subunit E M3Q_599 ENOG4107R4Z monovalent cation h antiporter subunit d M3Q_60 ENOG4105E0K tonB-dependent siderophore receptor M3Q_600 ENOG4108ZE9 Monovalent cation H antiporter subunit C M3Q_601 ENOG4105D65 subunit l M3Q_604 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase M3Q_605 ENOG41061H0 Monooxygenase M3Q_608 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) M3Q_610 ENOG4105CSR polyphosphate kinase 2 M3Q_612 ENOG4105DSY exodeoxyribonuclease V, gamma M3Q_613 ENOG4107QKA exodeoxyribonuclease V beta M3Q_614 ENOG4107QYX exodeoxyribonuclease v alpha M3Q_618 ENOG4107QUT magnesium and cobalt transport protein CorA M3Q_619 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) M3Q_620 ENOG4105DVC DnaJ domain protein M3Q_622 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) M3Q_623 ENOG4105CKD glutathione-regulated potassium-efflux system protein M3Q_624 ENOG4105C25 Primosomal protein n' M3Q_625 ENOG4105D7Q type ii secretion system M3Q_626 ENOG4108VAU general secretion pathway protein G M3Q_628 ENOG4108Z7R Chaperone CsaA M3Q_629 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) M3Q_63 ENOG4107QSN dihydrolipoamide acetyltransferase M3Q_630 ENOG4108JU5 Magnesium and cobalt efflux protein M3Q_631 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) M3Q_632 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase M3Q_634 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) M3Q_637 ENOG4105C5X domain protein M3Q_638 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) M3Q_64 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) M3Q_646 ENOG4107T8P acyl-Coa dehydrogenase M3Q_648 ENOG4107QI1 Mate efflux family protein M3Q_65 ENOG41063SB peptidase M3Q_650 ENOG4105CSA Coproporphyrinogen iii oxidase M3Q_651 ENOG4105EMU Dehydrogenase M3Q_652 ENOG4105CBN LysR family transcriptional regulator M3Q_654 ENOG4105C03 ribonuclease M3Q_655 ENOG4105EI2 Pseudouridine synthase M3Q_656 ENOG4107XGZ Hydrolase M3Q_657 ENOG4105D29 Helix-turn-helix type 11 domain protein M3Q_660 ENOG4108W5M transcriptional regulator M3Q_663 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase M3Q_668 ENOG4105DUM transcriptional regulator, lysR family M3Q_673 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) M3Q_68 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) M3Q_684 ENOG4105CK2 sodium dicarboxylate symporter M3Q_686 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase M3Q_687 ENOG4105N14 lysine exporter protein LysE YggA M3Q_688 ENOG4105C5H ABC transporter M3Q_689 ENOG41069P5 Protein slyX homolog M3Q_69 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) M3Q_691 ENOG4105KVH Transcriptional regulator M3Q_693 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) M3Q_696 ENOG4105C4R Atp-dependent dna helicase M3Q_697 ENOG4105VFU Rna-binding protein M3Q_70 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) M3Q_701 ENOG4105CKD glutathione-regulated potassium-efflux system protein M3Q_702 ENOG4105W0E 50S ribosomal protein L33 M3Q_703 ENOG4105KDC 50s ribosomal protein l28 M3Q_704 ENOG4107RGH Aldehyde dehydrogenase M3Q_706 ENOG4105CIY formyltetrahydrofolate deformylase M3Q_726 ENOG4105DWV Homoserine O-trans-acetylase M3Q_728 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) M3Q_730 ENOG4108ESX Receptor M3Q_732 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) M3Q_736 ENOG4107GFK fumarate M3Q_737 ENOG4108DNC Involved in acetate metabolism (By similarity) M3Q_738 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) M3Q_739 ENOG4105C01 Dihydroxy-acid dehydratase M3Q_74 ENOG4105D7Z glutathione synthase M3Q_740 ENOG4108UHU Aldolase M3Q_741 ENOG4105C6Z Gluconate M3Q_742 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family M3Q_743 ENOG4105C26 Dehydrogenase M3Q_745 ENOG4106HB6 Alpha beta hydrolase M3Q_748 ENOG4105CN1 protease M3Q_751 ENOG4105WVQ Fe-S assembly protein IscX M3Q_755 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) M3Q_759 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) M3Q_763 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) M3Q_766 ENOG4105CEY Amp-dependent synthetase and ligase M3Q_769 ENOG4105C84 Histidine ammonia-lyase M3Q_775 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) M3Q_777 ENOG4105C2D reductase M3Q_778 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) M3Q_782 ENOG4105VW4 glutaredoxin 3 M3Q_784 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) M3Q_785 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) M3Q_787 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH M3Q_788 ENOG4105ENJ RND efflux system, outer membrane lipoprotein M3Q_789 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) M3Q_790 ENOG4105DJY efflux transporter, rnd family, mfp subunit M3Q_795 ENOG4105C7K acetolactate synthase M3Q_796 ENOG4108ZP8 Acetolactate synthase small subunit M3Q_798 ENOG4105BZU Histidine kinase M3Q_802 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) M3Q_805 ENOG4105F8V Hydrolase, tatD family M3Q_806 ENOG4107QM5 aconitate hydratase M3Q_808 ENOG4105CUZ uba thif-type nad fad binding protein M3Q_809 ENOG4107RSM transcriptional regulator M3Q_81 ENOG4105CGK Exodeoxyribonuclease III M3Q_811 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) M3Q_814 ENOG4106UX7 integral membrane protein M3Q_815 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) M3Q_816 ENOG4105W8H transhydrogenase (subunit alpha M3Q_817 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) M3Q_82 ENOG4105KUZ arsenate reductase M3Q_820 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) M3Q_821 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase M3Q_822 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase M3Q_823 ENOG4105BZU Histidine kinase M3Q_824 ENOG4105C6T cysteine synthase M3Q_827 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) M3Q_829 ENOG4105DXN mazG family M3Q_830 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein M3Q_831 ENOG4105DJ0 Poly(A) Polymerase M3Q_832 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase M3Q_836 ENOG41080Z8 PHOSPHOCARRIER protein M3Q_837 ENOG4105N42 UPF0307 protein M3Q_838 ENOG4105CEY Amp-dependent synthetase and ligase M3Q_841 ENOG4105CYM Glutathione S-transferase M3Q_842 ENOG4105W39 Membrane M3Q_845 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) M3Q_85 ENOG4105BZU Histidine kinase M3Q_850 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) M3Q_853 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) M3Q_855 ENOG4105C9X ppx gppa phosphatase M3Q_857 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) M3Q_858 ENOG4105II7 pyrroline-5-carboxylate reductase M3Q_859 ENOG4108VIA integral membrane protein M3Q_86 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) M3Q_860 ENOG4105C2M dna polymerase I M3Q_864 ENOG4107QHF type ii secretion system protein e M3Q_865 ENOG4108ZHJ Organic hydroperoxide resistance protein M3Q_866 ENOG4105K56 Transcriptional regulator M3Q_875 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) M3Q_876 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) M3Q_877 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) M3Q_879 ENOG4105CRQ synthase (Component I) M3Q_888 ENOG4108Z0R Transferase M3Q_889 ENOG41072GX Peptidase M22 Glycoprotease M3Q_894 ENOG4105DJV ribulose-phosphate 3-epimerase M3Q_895 ENOG4108HCJ Hydrolase M3Q_897 ENOG4105E3B Multicopper oxidase M3Q_898 ENOG4105VR0 copper resistance M3Q_901 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) M3Q_902 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) M3Q_903 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) M3Q_906 ENOG4105ETT transcriptional Regulator, LysR family M3Q_907 ENOG4105C1G acyl-Coa dehydrogenase M3Q_908 ENOG4107RGD Major Facilitator superfamily M3Q_909 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F M3Q_911 ENOG4107EFR Flavocytochrome c M3Q_915 ENOG4106P55 Transcriptional regulator M3Q_917 ENOG4105CH2 amidohydrolase M3Q_92 ENOG41084YZ Hydrolase M3Q_921 ENOG4105ETT transcriptional Regulator, LysR family M3Q_923 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) M3Q_924 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) M3Q_929 ENOG4105JAB phenazine biosynthesis protein, phzf family M3Q_933 ENOG4105DZG Dehydrogenase M3Q_947 ENOG4105EB3 Histidine kinase M3Q_948 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) M3Q_95 ENOG41061H0 Monooxygenase M3Q_950 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) M3Q_951 ENOG4107EXC regulatoR M3Q_952 ENOG4105E0F Histidine kinase M3Q_954 ENOG4105BZU Histidine kinase M3Q_958 ENOG4105GKE subunit e M3Q_959 ENOG4107QIZ NADH dehydrogenase M3Q_960 ENOG4108IEH NADH dehydrogenase subunit g M3Q_963 ENOG4107UFS subunit j M3Q_965 ENOG4105D65 subunit l M3Q_966 ENOG4105C8S subunit m M3Q_97 ENOG4108Z2U ureidoglycolate hydrolase M3Q_970 ENOG4105DUM transcriptional regulator, lysR family M3Q_971 ENOG4105DP0 ferredoxin-NADP reductase M3Q_976 ENOG4105CBX hi0933 family M3Q_977 ENOG4105K6H D-cysteine desulfhydrase M3Q_98 ENOG4105EWI Short-chain dehydrogenase reductase Sdr M3Q_983 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) M3Q_985 ENOG4105D1F ATP-binding protein M3Q_99 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) M3Q_995 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) M3Q_997 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY