locus-tag	class	description
M3Q_100	COG3150	esterase
M3Q_1000	COG0730	response to heat
M3Q_1002	COG1196	nuclear chromosome segregation
M3Q_1006	COG2223	nitrite transmembrane transporter activity
M3Q_1007	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
M3Q_1008	COG1877	trehalose-phosphatase activity
M3Q_1009	COG0596	Alpha beta hydrolase
M3Q_1009	COG2226	methyltransferase
M3Q_1009	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
M3Q_1012	COG4106	trans-aconitate 2-methyltransferase activity
M3Q_1015	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
M3Q_1016	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
M3Q_1017	COG0009	L-threonylcarbamoyladenylate synthase
M3Q_1018	COG3101	peptidyl-lysine hydroxylation
M3Q_1019	COG1399	metal-binding, possibly nucleic acid-binding protein
M3Q_1023	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M3Q_1024	COG1652	LysM domain
M3Q_1025	COG0351	phosphomethylpyrimidine kinase
M3Q_1025	COG0352	thiamine-phosphate diphosphorylase activity
M3Q_1027	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
M3Q_1033	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
M3Q_1035	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
M3Q_1038	COG0358	DNA primase activity
M3Q_1040	COG0564	pseudouridine synthase activity
M3Q_1045	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
M3Q_1047	COG0583	DNA-binding transcription factor activity
M3Q_1048	COG0473	3-isopropylmalate dehydrogenase activity
M3Q_1052	COG1012	belongs to the aldehyde dehydrogenase family
M3Q_1055	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M3Q_1055	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
M3Q_1067	COG0456	acetyltransferase
M3Q_1069	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
M3Q_1070	COG0492	ferredoxin-NADP+ reductase activity
M3Q_1071	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
M3Q_1071	COG1674	ftsk spoiiie
M3Q_1072	COG1280	lysine exporter protein (LysE YggA)
M3Q_1076	COG2894	cell division
M3Q_1079	COG0204	Acyl-transferase
M3Q_1080	COG2885	chlorophyll binding
M3Q_1081	COG0210	DNA helicase
M3Q_1083	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M3Q_1086	COG0121	glutamine amidotransferase
M3Q_1090	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
M3Q_1091	COG0735	belongs to the Fur family
M3Q_1096	COG0420	3'-5' exonuclease activity
M3Q_11	COG1335	isochorismatase
M3Q_110	COG1388	LysM domain
M3Q_110	COG3409	Peptidoglycan-binding domain 1 protein
M3Q_110	COG5632	N-Acetylmuramoyl-L-alanine amidase
M3Q_1100	COG1090	epimerase
M3Q_1103	COG2050	protein possibly involved in aromatic compounds catabolism
M3Q_1105	COG2814	Major facilitator Superfamily
M3Q_1106	COG0405	Gamma-glutamyltransferase
M3Q_111	COG3501	Rhs element vgr protein
M3Q_1119	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M3Q_1137	COG1484	DNA-dependent DNA replication
M3Q_114	COG2918	glutathione biosynthetic process
M3Q_1146	COG3755	Protein conserved in bacteria
M3Q_117	COG2733	membrane
M3Q_1175	COG2026	Addiction module toxin, RelE StbE family
M3Q_118	COG0436	Aminotransferase
M3Q_1183	COG0592	DNA-directed DNA polymerase activity
M3Q_119	COG0534	Mate efflux family protein
M3Q_1207	COG0477	Major facilitator Superfamily
M3Q_1208	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M3Q_1210	COG1595	DNA-templated transcription, initiation
M3Q_1221	COG0531	amino acid
M3Q_1222	COG2040	homocysteine
M3Q_1227	COG1309	transcriptional regulator
M3Q_1228	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M3Q_1229	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M3Q_1231	COG1607	acyl-coa hydrolase
M3Q_1233	COG0523	cobalamin synthesis protein
M3Q_1235	COG4681	YaeQ
M3Q_1237	COG1649	PFAM Uncharacterised BCR, COG1649
M3Q_1237	COG0726	polysaccharide deacetylase
M3Q_1238	COG1215	transferase activity, transferring glycosyl groups
M3Q_1240	COG1024	Enoyl-CoA hydratase
M3Q_1243	COG1414	Transcriptional regulator
M3Q_1247	COG1028	Short-chain dehydrogenase reductase Sdr
M3Q_1249	COG0446	pyridine nucleotide-disulphide oxidoreductase
M3Q_1250	COG2271	Major facilitator Superfamily
M3Q_1252	COG2267	carboxylic ester hydrolase activity
M3Q_1253	COG1028	Short-chain dehydrogenase reductase Sdr
M3Q_1256	COG0028	Belongs to the TPP enzyme family
M3Q_1258	COG0477	Major facilitator Superfamily
M3Q_1259	COG0242	peptide deformylase activity
M3Q_1260	COG2066	Belongs to the glutaminase family
M3Q_1261	COG2207	Transcriptional regulator
M3Q_1262	COG2223	nitrite transmembrane transporter activity
M3Q_1265	COG0583	DNA-binding transcription factor activity
M3Q_1266	COG1028	Short-chain dehydrogenase reductase Sdr
M3Q_1267	COG2271	Major facilitator Superfamily
M3Q_1268	COG3959	Transketolase, thiamine diphosphate binding domain
M3Q_1269	COG3958	Transketolase
M3Q_1271	COG0306	phosphate transporter
M3Q_1275	COG1262	PFAM Formylglycine-generating sulfatase enzyme
M3Q_1284	COG4181	ATPase activity
M3Q_1285	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
M3Q_1290	COG0583	DNA-binding transcription factor activity
M3Q_1292	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M3Q_1293	COG1773	rubredoxin
M3Q_13	COG1012	belongs to the aldehyde dehydrogenase family
M3Q_1303	COG2851	Citrate transporter
M3Q_1304	COG1253	flavin adenine dinucleotide binding
M3Q_1312	COG0804	urea catabolic process
M3Q_1314	COG0830	nickel cation binding
M3Q_1317	COG0742	ribosomal rna small subunit methyltransferase
M3Q_1318	COG0768	penicillin binding
M3Q_1322	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
M3Q_1323	COG2878	Part of a membrane complex involved in electron transport
M3Q_1324	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M3Q_1326	COG3384	dioxygenase
M3Q_1331	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
M3Q_136	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
M3Q_137	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
M3Q_139	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
M3Q_1390	COG0739	heme binding
M3Q_1399	COG2194	sulfuric ester hydrolase activity
M3Q_14	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M3Q_140	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
M3Q_141	COG0546	phosphoglycolate phosphatase activity
M3Q_1410	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
M3Q_143	COG0010	Belongs to the arginase family
M3Q_1434	COG4695	Portal protein
M3Q_1446	COG1196	nuclear chromosome segregation
M3Q_1446	COG0741	lytic transglycosylase activity
M3Q_1446	COG0739	heme binding
M3Q_1461	COG0006	proline dipeptidase activity
M3Q_1462	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M3Q_1463	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M3Q_1467	COG1279	arginine transmembrane transporter activity
M3Q_1468	COG0583	DNA-binding transcription factor activity
M3Q_1476	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M3Q_1477	COG0741	lytic transglycosylase activity
M3Q_1477	COG1388	LysM domain
M3Q_1477	COG0741	lytic transglycosylase activity
M3Q_1477	COG1388	LysM domain
M3Q_1479	COG4174	ABC transporter (Permease)
M3Q_1480	COG4239	(ABC) transporter, permease
M3Q_1481	COG4172	Belongs to the ABC transporter superfamily
M3Q_1484	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M3Q_1486	COG3706	GGDEF domain
M3Q_1486	COG5001	Diguanylate cyclase
M3Q_1486	COG2203	Gaf domain
M3Q_1486	COG4251	negative regulation of phosphorylation
M3Q_1488	COG0446	pyridine nucleotide-disulphide oxidoreductase
M3Q_1488	COG1902	pentaerythritol trinitrate reductase activity
M3Q_149	COG2188	Transcriptional regulator
M3Q_1490	COG4269	membrane
M3Q_1494	COG3501	Rhs element vgr protein
M3Q_1495	COG3209	COG3209 Rhs family protein
M3Q_1503	COG1113	amino acid transport
M3Q_1505	COG0531	amino acid
M3Q_1509	COG1012	belongs to the aldehyde dehydrogenase family
M3Q_151	COG0523	cobalamin synthesis protein
M3Q_1513	COG1113	amino acid transport
M3Q_1514	COG3316	Transposase and inactivated derivatives
M3Q_1516	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
M3Q_1517	COG3316	Transposase and inactivated derivatives
M3Q_1519	COG1741	Belongs to the pirin family
M3Q_1522	COG2072	flavoprotein involved in K transport
M3Q_1524	COG2252	PERMEase
M3Q_1525	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
M3Q_1526	COG3038	cytochrome b561
M3Q_1528	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
M3Q_153	COG1113	amino acid transport
M3Q_1532	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
M3Q_1534	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
M3Q_1537	COG0667	Aldo Keto reductase
M3Q_1541	COG1765	OsmC-like protein
M3Q_155	COG0625	glutathione transferase activity
M3Q_1551	COG2885	chlorophyll binding
M3Q_1553	COG0625	glutathione transferase activity
M3Q_1554	COG0220	tRNA (guanine-N7-)-methyltransferase activity
M3Q_1558	COG3634	alkyl hydroperoxide reductase activity
M3Q_1560	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
M3Q_1562	COG0450	alkyl hydroperoxide reductase
M3Q_1563	COG1643	Atp-dependent helicase
M3Q_1566	COG2814	Major facilitator Superfamily
M3Q_1567	COG3135	benzoate transporter
M3Q_1568	COG1028	Short-chain dehydrogenase reductase Sdr
M3Q_1569	COG0543	2 iron, 2 sulfur cluster binding
M3Q_1569	COG0633	Ferredoxin
M3Q_1570	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
M3Q_1571	COG4638	Rieske (2fe-2S)
M3Q_1572	COG0583	DNA-binding transcription factor activity
M3Q_1582	COG1570	exodeoxyribonuclease VII activity
M3Q_1588	COG1280	lysine exporter protein (LysE YggA)
M3Q_1589	COG1278	Cold shock
M3Q_159	COG1683	Conserved Protein
M3Q_1596	COG2814	Major facilitator Superfamily
M3Q_1597	COG1733	regulation of RNA biosynthetic process
M3Q_16	COG1113	amino acid transport
M3Q_160	COG0534	Mate efflux family protein
M3Q_1603	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
M3Q_1603	COG0517	IMP dehydrogenase activity
M3Q_1604	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
M3Q_1606	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
M3Q_1607	COG1137	ATPase activity
M3Q_1608	COG1538	Outer membrane efflux protein
M3Q_161	COG0385	Bile acid
M3Q_1616	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
M3Q_1619	COG1522	sequence-specific DNA binding
M3Q_162	COG1335	isochorismatase
M3Q_1620	COG5006	permease, DMT superfamily
M3Q_1622	COG1560	Kdo2-lipid A biosynthetic process
M3Q_1624	COG2814	Major facilitator Superfamily
M3Q_1628	COG1250	3-hydroxyacyl-CoA dehydrogenase
M3Q_163	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M3Q_1633	COG3501	Rhs element vgr protein
M3Q_1634	COG3209	COG3209 Rhs family protein
M3Q_1638	COG1914	H( )-stimulated, divalent metal cation uptake system
M3Q_1642	COG4770	biotin carboxylase activity
M3Q_1643	COG0038	chloride channel
M3Q_1648	COG1309	transcriptional regulator
M3Q_1650	COG1063	alcohol dehydrogenase
M3Q_1653	COG0439	Biotin carboxylase
M3Q_1654	COG2249	NAD(P)H dehydrogenase (quinone) activity
M3Q_1655	COG1733	regulation of RNA biosynthetic process
M3Q_1658	COG0864	Transcriptional regulator
M3Q_1660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M3Q_1661	COG1116	anion transmembrane transporter activity
M3Q_167	COG2116	formate transmembrane transporter activity
M3Q_1674	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
M3Q_1674	COG2885	chlorophyll binding
M3Q_168	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
M3Q_1682	COG0583	DNA-binding transcription factor activity
M3Q_1685	COG2807	transmembrane transport
M3Q_1688	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
M3Q_169	COG2133	pyrroloquinoline quinone binding
M3Q_1693	COG1012	belongs to the aldehyde dehydrogenase family
M3Q_1694	COG0531	amino acid
M3Q_1695	COG1760	l-serine dehydratase
M3Q_1696	COG2030	dehydratase
M3Q_1696	COG1012	belongs to the aldehyde dehydrogenase family
M3Q_1697	COG3396	Phenylacetate-CoA oxygenase
M3Q_1698	COG3460	Phenylacetate-CoA oxygenase
M3Q_1699	COG3396	Phenylacetate-CoA oxygenase
M3Q_170	COG2983	Belongs to the UPF0260 family
M3Q_1700	COG2151	metal-sulfur cluster biosynthetic enzyme
M3Q_1701	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M3Q_1702	COG1024	Enoyl-CoA hydratase
M3Q_1703	COG1024	Enoyl-CoA hydratase
M3Q_1704	COG1250	3-hydroxyacyl-CoA dehydrogenase
M3Q_1705	COG0183	Belongs to the thiolase family
M3Q_1706	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
M3Q_1707	COG3327	negative regulation of DNA-templated transcription, initiation
M3Q_1709	COG2050	protein possibly involved in aromatic compounds catabolism
M3Q_1716	COG0753	catalase activity
M3Q_1717	COG3038	cytochrome b561
M3Q_1721	COG2267	carboxylic ester hydrolase activity
M3Q_1722	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M3Q_1723	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M3Q_1724	COG1012	belongs to the aldehyde dehydrogenase family
M3Q_1725	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
M3Q_1727	COG1012	belongs to the aldehyde dehydrogenase family
M3Q_1728	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M3Q_1729	COG0583	DNA-binding transcription factor activity
M3Q_1731	COG1414	Transcriptional regulator
M3Q_1732	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M3Q_1734	COG1840	ABC-type Fe3 transport system, periplasmic component
M3Q_1735	COG3842	ATPase activity
M3Q_1738	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
M3Q_1739	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M3Q_174	COG1194	a g-specific adenine glycosylase
M3Q_1740	COG2814	Major facilitator Superfamily
M3Q_1741	COG1960	acyl-CoA dehydrogenase activity
M3Q_1744	COG1024	Enoyl-CoA hydratase
M3Q_1746	COG2814	Major facilitator Superfamily
M3Q_1748	COG0183	Belongs to the thiolase family
M3Q_1749	COG1250	3-hydroxyacyl-CoA dehydrogenase
M3Q_1750	COG1028	Short-chain dehydrogenase reductase Sdr
M3Q_1751	COG1024	Enoyl-CoA hydratase
M3Q_1752	COG1960	acyl-CoA dehydrogenase activity
M3Q_1753	COG2814	Major facilitator Superfamily
M3Q_1754	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M3Q_1755	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M3Q_1757	COG2814	Major facilitator Superfamily
M3Q_1759	COG1960	acyl-CoA dehydrogenase activity
M3Q_1762	COG0583	DNA-binding transcription factor activity
M3Q_1765	COG1024	Enoyl-CoA hydratase
M3Q_1766	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
M3Q_1767	COG1960	acyl-CoA dehydrogenase activity
M3Q_1768	COG1309	transcriptional regulator
M3Q_1769	COG0318	PFAM AMP-dependent synthetase and ligase
M3Q_177	COG2818	Glycosylase
M3Q_1773	COG0583	DNA-binding transcription factor activity
M3Q_178	COG1064	alcohol dehydrogenase
M3Q_1784	COG1028	Short-chain dehydrogenase reductase Sdr
M3Q_1787	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
M3Q_179	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M3Q_1791	COG2205	protein histidine kinase activity
M3Q_1791	COG0784	Response regulator, receiver
M3Q_1794	COG0765	amino acid transport
M3Q_1795	COG0765	amino acid transport
M3Q_1796	COG1126	abc transporter atp-binding protein
M3Q_1797	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M3Q_1798	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M3Q_18	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
M3Q_1800	COG1280	lysine exporter protein (LysE YggA)
M3Q_1801	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
M3Q_1802	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M3Q_1803	COG1045	serine acetyltransferase
M3Q_1806	COG0583	DNA-binding transcription factor activity
M3Q_1807	COG0625	glutathione transferase activity
M3Q_1808	COG0625	glutathione transferase activity
M3Q_1809	COG0583	DNA-binding transcription factor activity
M3Q_181	COG0583	DNA-binding transcription factor activity
M3Q_1811	COG1346	cytolysis
M3Q_1815	COG2814	Major facilitator Superfamily
M3Q_1817	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
M3Q_1818	COG3052	prosthetic group binding
M3Q_182	COG0656	L-ascorbic acid biosynthetic process
M3Q_1822	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M3Q_1826	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M3Q_1828	COG1294	oxidase, subunit
M3Q_1829	COG1271	oxidase subunit
M3Q_183	COG2814	Major facilitator Superfamily
M3Q_1833	COG0477	Major facilitator Superfamily
M3Q_1836	COG4521	taurine ABC transporter
M3Q_1837	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
M3Q_1838	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M3Q_1839	COG2175	clavaminate synthase activity
M3Q_1841	COG2814	Major facilitator Superfamily
M3Q_1842	COG0318	PFAM AMP-dependent synthetase and ligase
M3Q_1843	COG1960	acyl-CoA dehydrogenase activity
M3Q_1844	COG3321	synthase
M3Q_1844	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M3Q_1844	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
M3Q_1844	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
M3Q_1846	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M3Q_1849	COG2267	carboxylic ester hydrolase activity
M3Q_1851	COG0271	Belongs to the BolA IbaG family
M3Q_1855	COG0436	Aminotransferase
M3Q_1857	COG0386	Belongs to the glutathione peroxidase family
M3Q_1865	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
M3Q_1870	COG0012	GTP binding
M3Q_1871	COG2011	ABC-type metal ion transport system permease component
M3Q_1872	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M3Q_1876	COG1464	Belongs to the NlpA lipoprotein family
M3Q_1882	COG0765	amino acid transport
M3Q_1883	COG0765	amino acid transport
M3Q_1884	COG1126	abc transporter atp-binding protein
M3Q_1886	COG1522	sequence-specific DNA binding
M3Q_1889	COG1309	transcriptional regulator
M3Q_1893	COG0583	DNA-binding transcription factor activity
M3Q_1895	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
M3Q_1897	COG0697	spore germination
M3Q_190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M3Q_1902	COG3121	Chaperone
M3Q_1903	COG3539	Fimbrial protein
M3Q_1908	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
M3Q_1908	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
M3Q_1917	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
M3Q_1919	COG2353	YceI-like domain
M3Q_1921	COG3698	Phosphodiester glycosidase
M3Q_1924	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
M3Q_1925	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
M3Q_1925	COG0506	proline dehydrogenase activity
M3Q_1925	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
M3Q_1927	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M3Q_1928	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
M3Q_193	COG2233	PERMEase
M3Q_1932	COG1132	(ABC) transporter
M3Q_1934	COG3122	Protein conserved in bacteria
M3Q_1935	COG3619	membrane
M3Q_1937	COG0640	Transcriptional regulator
M3Q_1939	COG2850	peptidyl-arginine hydroxylation
M3Q_194	COG0583	DNA-binding transcription factor activity
M3Q_1940	COG0424	maF-like protein
M3Q_1944	COG0191	fructose-bisphosphate aldolase activity
M3Q_1945	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M3Q_1948	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
M3Q_1950	COG1192	Involved in chromosome partitioning
M3Q_1951	COG1475	DNA binding
M3Q_1952	COG0811	peptide transport
M3Q_1954	COG1132	(ABC) transporter
M3Q_1955	COG1663	tetraacyldisaccharide 4'-kinase activity
M3Q_1959	COG0084	hydrolase, TatD family'
M3Q_1962	COG2165	general secretion pathway protein
M3Q_1968	COG0590	tRNA wobble adenosine to inosine editing
M3Q_1972	COG0776	regulation of translation
M3Q_1978	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
M3Q_1979	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
M3Q_198	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
M3Q_1989	COG0339	signal peptide processing
M3Q_1991	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M3Q_1998	COG0702	epimerase
M3Q_1999	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
M3Q_2003	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
M3Q_2009	COG0316	Belongs to the HesB IscA family
M3Q_2010	COG0822	iron-sulfur transferase activity
M3Q_2015	COG0776	regulation of translation
M3Q_2016	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M3Q_2017	COG2207	Transcriptional regulator
M3Q_2018	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M3Q_2019	COG1960	acyl-CoA dehydrogenase activity
M3Q_2020	COG1960	acyl-CoA dehydrogenase activity
M3Q_2023	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
M3Q_2027	COG4264	IucA IucC family
M3Q_2028	COG4264	IucA IucC family
M3Q_203	COG0583	DNA-binding transcription factor activity
M3Q_2039	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
M3Q_2043	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
M3Q_2044	COG0730	response to heat
M3Q_2048	COG4773	Receptor
M3Q_2049	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
M3Q_2052	COG1131	(ABC) transporter
M3Q_2053	COG0842	Transport permease protein
M3Q_2054	COG0842	Transport permease protein
M3Q_2065	COG2226	methyltransferase
M3Q_2070	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
M3Q_2077	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M3Q_2079	COG0133	tryptophan synthase activity
M3Q_2082	COG3706	GGDEF domain
M3Q_2085	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
M3Q_2086	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M3Q_2087	COG0022	dehydrogenase e1 component
M3Q_2088	COG0508	dehydrogenase complex catalyzes the overall conversion of
M3Q_2089	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M3Q_209	COG2951	lytic endotransglycosylase activity
M3Q_2091	COG1063	alcohol dehydrogenase
M3Q_2092	COG3781	membrane
M3Q_2094	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M3Q_2094	COG3453	Protein conserved in bacteria
M3Q_2096	COG0730	response to heat
M3Q_2099	COG3708	Transcriptional regulator
M3Q_2099	COG2207	Transcriptional regulator
M3Q_21	COG2814	Major facilitator Superfamily
M3Q_210	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
M3Q_2100	COG1733	regulation of RNA biosynthetic process
M3Q_2101	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
M3Q_2106	COG4521	taurine ABC transporter
M3Q_2107	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M3Q_2111	COG0477	Major facilitator Superfamily
M3Q_2113	COG1027	Aspartate ammonia-lyase
M3Q_2116	COG0583	DNA-binding transcription factor activity
M3Q_2117	COG0583	DNA-binding transcription factor activity
M3Q_2118	COG0183	Belongs to the thiolase family
M3Q_2119	COG2031	fatty acid transporter
M3Q_2120	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M3Q_2122	COG0583	DNA-binding transcription factor activity
M3Q_2124	COG2610	gluconate transmembrane transporter activity
M3Q_2125	COG1028	Short-chain dehydrogenase reductase Sdr
M3Q_2128	COG2207	Transcriptional regulator
M3Q_213	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
M3Q_2130	COG0412	Dienelactone hydrolase
M3Q_2131	COG1028	Short-chain dehydrogenase reductase Sdr
M3Q_2133	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M3Q_2136	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M3Q_2136	COG0543	2 iron, 2 sulfur cluster binding
M3Q_2137	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
M3Q_2138	COG4638	Rieske (2fe-2S)
M3Q_2140	COG0725	ABC transporter, periplasmic molybdate-binding protein
M3Q_2141	COG4149	molybdate abc transporter
M3Q_2142	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
M3Q_2143	COG1028	Short-chain dehydrogenase reductase Sdr
M3Q_2144	COG3433	isochorismatase activity
M3Q_2144	COG1535	isochorismatase
M3Q_215	COG0671	phosphoesterase, PA-phosphatase related
M3Q_2156	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M3Q_2159	COG0753	catalase activity
M3Q_216	COG0861	Integral membrane protein TerC family
M3Q_2161	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
M3Q_2168	COG3539	Fimbrial protein
M3Q_2172	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M3Q_2176	COG2072	flavoprotein involved in K transport
M3Q_2178	COG1538	Outer membrane efflux protein
M3Q_2179	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M3Q_218	COG0754	glutathionylspermidine amidase activity
M3Q_2180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M3Q_2181	COG0745	RESPONSE REGULATOR receiver
M3Q_2182	COG2205	protein histidine kinase activity
M3Q_2184	COG2207	Transcriptional regulator
M3Q_2187	COG1028	Short-chain dehydrogenase reductase Sdr
M3Q_2198	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
M3Q_220	COG0592	DNA-directed DNA polymerase activity
M3Q_222	COG0230	Belongs to the bacterial ribosomal protein bL34 family
M3Q_2221	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
M3Q_2225	COG1120	ATPase activity
M3Q_2228	COG1064	alcohol dehydrogenase
M3Q_2231	COG2207	Transcriptional regulator
M3Q_2232	COG2084	Dehydrogenase
M3Q_2234	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M3Q_2235	COG0583	DNA-binding transcription factor activity
M3Q_2237	COG0129	dihydroxy-acid dehydratase activity
M3Q_2238	COG1012	belongs to the aldehyde dehydrogenase family
M3Q_2241	COG1566	PFAM secretion protein HlyD family protein
M3Q_2245	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
M3Q_2246	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M3Q_225	COG0706	membrane insertase activity
M3Q_2251	COG0583	DNA-binding transcription factor activity
M3Q_2260	COG3210	domain, Protein
M3Q_2261	COG2831	hemolysin activation secretion protein
M3Q_2263	COG1473	amidohydrolase
M3Q_2265	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M3Q_2265	COG0475	glutathione-regulated potassium exporter activity
M3Q_2267	COG0583	DNA-binding transcription factor activity
M3Q_2268	COG1335	isochorismatase
M3Q_2270	COG1309	transcriptional regulator
M3Q_2276	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M3Q_2278	COG1902	pentaerythritol trinitrate reductase activity
M3Q_2278	COG0446	pyridine nucleotide-disulphide oxidoreductase
M3Q_2279	COG1846	Transcriptional regulator
M3Q_228	COG1230	cation diffusion facilitator family transporter
M3Q_2283	COG0753	catalase activity
M3Q_2286	COG1012	belongs to the aldehyde dehydrogenase family
M3Q_2289	COG3162	membrane
M3Q_229	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M3Q_2291	COG3829	transcription factor binding
M3Q_2292	COG1028	Short-chain dehydrogenase reductase Sdr
M3Q_2293	COG1960	acyl-CoA dehydrogenase activity
M3Q_2297	COG1012	belongs to the aldehyde dehydrogenase family
M3Q_23	COG0351	phosphomethylpyrimidine kinase
M3Q_23	COG0352	thiamine-phosphate diphosphorylase activity
M3Q_23	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
M3Q_2301	COG2186	Transcriptional regulator
M3Q_2303	COG0583	DNA-binding transcription factor activity
M3Q_2304	COG4948	Mandelate Racemase Muconate Lactonizing
M3Q_2305	COG4829	muconolactone delta-isomerase
M3Q_2307	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M3Q_2308	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M3Q_2309	COG0183	Belongs to the thiolase family
M3Q_2310	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
M3Q_2312	COG1012	belongs to the aldehyde dehydrogenase family
M3Q_2314	COG3733	amine oxidase
M3Q_2316	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M3Q_2318	COG1028	Short-chain dehydrogenase reductase Sdr
M3Q_2320	COG4638	Rieske (2fe-2S)
M3Q_2324	COG0154	amidase activity
M3Q_2326	COG2814	Major facilitator Superfamily
M3Q_233	COG0402	S-adenosylhomocysteine deaminase activity
M3Q_2331	COG1960	acyl-CoA dehydrogenase activity
M3Q_2332	COG0583	DNA-binding transcription factor activity
M3Q_2333	COG1414	Transcriptional regulator
M3Q_2336	COG2391	methyltransferase activity
M3Q_2338	COG4993	Dehydrogenase
M3Q_2339	COG3659	wide pore channel activity
M3Q_2340	COG3420	alginic acid biosynthetic process
M3Q_2341	COG0710	3-dehydroquinate dehydratase activity
M3Q_2342	COG3485	protocatechuate 3,4-dioxygenase
M3Q_2343	COG3485	protocatechuate 3,4-dioxygenase
M3Q_2344	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M3Q_2345	COG2271	Major facilitator Superfamily
M3Q_2346	COG0596	Alpha beta hydrolase
M3Q_2347	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
M3Q_2348	COG0183	Belongs to the thiolase family
M3Q_2349	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M3Q_2350	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M3Q_2352	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
M3Q_2353	COG2323	membrane
M3Q_2362	COG0446	pyridine nucleotide-disulphide oxidoreductase
M3Q_2362	COG1902	pentaerythritol trinitrate reductase activity
M3Q_2365	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
M3Q_2367	COG0542	response to heat
M3Q_2368	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
M3Q_237	COG0187	DNA topoisomerase II activity
M3Q_2374	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
M3Q_2375	COG0569	domain protein
M3Q_2376	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M3Q_2379	COG4774	siderophore transport
M3Q_2380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M3Q_2382	COG1585	Membrane protein implicated in regulation of membrane protease activity
M3Q_2385	COG1294	oxidase, subunit
M3Q_2386	COG4890	Cyd operon protein YbgT
M3Q_2389	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
M3Q_239	COG0586	Pfam SNARE associated Golgi protein
M3Q_2391	COG0552	protein localization to endoplasmic reticulum
M3Q_2396	COG0516	GMP reductase activity
M3Q_2396	COG0517	IMP dehydrogenase activity
M3Q_2397	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M3Q_2398	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
M3Q_240	COG0488	(ABC) transporter
M3Q_2400	COG0583	DNA-binding transcription factor activity
M3Q_2401	COG0024	Methionine aminopeptidase
M3Q_2407	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
M3Q_2407	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
M3Q_2408	COG1105	Belongs to the carbohydrate kinase PfkB family
M3Q_2409	COG1105	Belongs to the carbohydrate kinase PfkB family
M3Q_2410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M3Q_2410	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
M3Q_2410	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M3Q_2415	COG5001	Diguanylate cyclase
M3Q_2415	COG3300	MHYT domain
M3Q_2418	COG2135	peptidase activity
M3Q_2419	COG0659	secondary active sulfate transmembrane transporter activity
M3Q_2422	COG1113	amino acid transport
M3Q_2424	COG1522	sequence-specific DNA binding
M3Q_2429	COG1011	Hydrolase
M3Q_2430	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
M3Q_2432	COG2137	regulation of response to DNA damage stimulus
M3Q_2434	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
M3Q_2441	COG0575	Belongs to the CDS family
M3Q_2442	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
M3Q_2446	COG3852	Histidine kinase
M3Q_2447	COG2204	response regulator
M3Q_245	COG0596	Alpha beta hydrolase
M3Q_2458	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M3Q_2459	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
M3Q_246	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
M3Q_2463	COG0697	spore germination
M3Q_2464	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M3Q_2466	COG0303	'Molybdopterin
M3Q_2467	COG0315	cyclic pyranopterin monophosphate synthase activity
M3Q_2467	COG0521	Mo-molybdopterin cofactor biosynthetic process
M3Q_247	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
M3Q_2470	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
M3Q_2471	COG0243	molybdopterin cofactor binding
M3Q_2473	COG0243	molybdopterin cofactor binding
M3Q_2474	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M3Q_2475	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M3Q_2475	COG2146	nitrite reductase [NAD(P)H] activity
M3Q_2476	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M3Q_2478	COG0745	RESPONSE REGULATOR receiver
M3Q_2479	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M3Q_2479	COG1116	anion transmembrane transporter activity
M3Q_2482	COG0511	ligase activity, forming carbon-carbon bonds
M3Q_2485	COG2814	Major facilitator Superfamily
M3Q_2489	COG0069	glutamate synthase activity
M3Q_2493	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
M3Q_2495	COG1454	alcohol dehydrogenase
M3Q_2496	COG0824	Thioesterase
M3Q_2499	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
M3Q_250	COG1047	Peptidyl-prolyl cis-trans
M3Q_2505	COG0183	Belongs to the thiolase family
M3Q_2507	COG0583	DNA-binding transcription factor activity
M3Q_2510	COG1522	sequence-specific DNA binding
M3Q_2511	COG3135	benzoate transporter
M3Q_2513	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
M3Q_2518	COG0589	response to stress
M3Q_2519	COG0488	(ABC) transporter
M3Q_252	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
M3Q_2523	COG4773	Receptor
M3Q_253	COG0196	riboflavin kinase activity
M3Q_2531	COG0668	transmembrane transport
M3Q_2533	COG1309	transcriptional regulator
M3Q_2536	COG1605	Chorismate mutase
M3Q_2538	COG4221	oxidoreductase activity
M3Q_2540	COG0308	aminopeptidase N
M3Q_2544	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
M3Q_2546	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M3Q_2547	COG1454	alcohol dehydrogenase
M3Q_255	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
M3Q_2551	COG0531	amino acid
M3Q_2552	COG4303	Ethanolamine ammonia lyase large subunit
M3Q_2553	COG4302	ethanolamine ammonia-lyase activity
M3Q_2554	COG0519	Catalyzes the synthesis of GMP from XMP
M3Q_2554	COG0518	GMP synthase (glutamine-hydrolyzing) activity
M3Q_256	COG1309	transcriptional regulator
M3Q_2560	COG0697	spore germination
M3Q_2561	COG1923	regulation of RNA biosynthetic process
M3Q_2563	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
M3Q_2564	COG0802	atpase or kinase
M3Q_2568	COG1187	pseudouridine synthase activity
M3Q_257	COG1116	anion transmembrane transporter activity
M3Q_2571	COG0583	DNA-binding transcription factor activity
M3Q_2574	COG2814	Major facilitator Superfamily
M3Q_2575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M3Q_258	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M3Q_2580	COG0729	surface antigen
M3Q_2584	COG0174	glutamine synthetase
M3Q_2585	COG0745	RESPONSE REGULATOR receiver
M3Q_2586	COG2205	protein histidine kinase activity
M3Q_2588	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
M3Q_2589	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
M3Q_259	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M3Q_2594	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M3Q_2595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M3Q_2596	COG1960	acyl-CoA dehydrogenase activity
M3Q_2599	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M3Q_260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M3Q_2600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M3Q_2604	COG0583	DNA-binding transcription factor activity
M3Q_2607	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M3Q_2609	COG3658	cytochrome
M3Q_261	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M3Q_2610	COG1215	transferase activity, transferring glycosyl groups
M3Q_2611	COG1649	PFAM Uncharacterised BCR, COG1649
M3Q_2611	COG0726	polysaccharide deacetylase
M3Q_2616	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
M3Q_2617	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
M3Q_2619	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
M3Q_2624	COG0305	Participates in initiation and elongation during chromosome replication
M3Q_2625	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M3Q_2627	COG1305	Transglutaminase-like
M3Q_2629	COG2308	Evidence 4 Homologs of previously reported genes of
M3Q_2635	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
M3Q_2636	COG0138	bifunctional purine biosynthesis protein purh
M3Q_2637	COG0151	Belongs to the GarS family
M3Q_2638	COG1464	Belongs to the NlpA lipoprotein family
M3Q_2639	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M3Q_2640	COG2011	ABC-type metal ion transport system permease component
M3Q_2641	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M3Q_2643	COG1301	dicarboxylic acid transport
M3Q_2646	COG3316	Transposase and inactivated derivatives
M3Q_265	COG1028	Short-chain dehydrogenase reductase Sdr
M3Q_2651	COG2433	Pfam Transposase IS66
M3Q_2653	COG3173	Aminoglycoside phosphotransferase
M3Q_266	COG0546	phosphoglycolate phosphatase activity
M3Q_2666	COG3316	Transposase and inactivated derivatives
M3Q_2671	COG1794	racemase activity, acting on amino acids and derivatives
M3Q_2673	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
M3Q_2673	COG3008	intermembrane lipid transfer
M3Q_2674	COG2995	paraquat-inducible protein a
M3Q_2676	COG2985	domain, Protein
M3Q_2680	COG0477	Major facilitator Superfamily
M3Q_2690	COG2186	Transcriptional regulator
M3Q_2692	COG0786	glutamate:sodium symporter activity
M3Q_2693	COG3243	poly(R)-hydroxyalkanoic acid synthase
M3Q_2698	COG3111	PFAM Bacterial OB fold (BOF) protein
M3Q_27	COG1309	transcriptional regulator
M3Q_2713	COG0828	Belongs to the bacterial ribosomal protein bS21 family
M3Q_2714	COG1610	YqeY-like protein
M3Q_2715	COG4783	chaperone-mediated protein folding
M3Q_2720	COG1286	toxin biosynthetic process
M3Q_2726	COG0778	Nitroreductase
M3Q_2728	COG0513	Belongs to the DEAD box helicase family
M3Q_2732	COG2363	Small membrane protein
M3Q_2738	COG1234	tRNA 3'-trailer cleavage
M3Q_2739	COG2195	Cleaves the N-terminal amino acid of tripeptides
M3Q_2741	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
M3Q_2743	COG2819	hydrolase of the alpha beta superfamily
M3Q_2744	COG1960	acyl-CoA dehydrogenase activity
M3Q_2745	COG1301	dicarboxylic acid transport
M3Q_2746	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
M3Q_2747	COG3139	Protein of unknown function (DUF1315)
M3Q_2748	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
M3Q_2749	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M3Q_2751	COG0494	nUDIX hydrolase
M3Q_2753	COG0642	Histidine kinase
M3Q_2754	COG0745	RESPONSE REGULATOR receiver
M3Q_2758	COG1720	tRNA m6t6A37 methyltransferase activity
M3Q_2761	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M3Q_2763	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
M3Q_2765	COG4598	ABC transporter
M3Q_2766	COG4160	amino acid transport
M3Q_2767	COG4215	(ABC) transporter
M3Q_277	COG3023	N-Acetylmuramoyl-L-alanine amidase
M3Q_2770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M3Q_2772	COG1538	Outer membrane efflux protein
M3Q_2778	COG1131	(ABC) transporter
M3Q_2779	COG0842	Transport permease protein
M3Q_278	COG0728	peptidoglycan biosynthetic process
M3Q_2782	COG0772	Belongs to the SEDS family
M3Q_2783	COG2951	lytic endotransglycosylase activity
M3Q_2788	COG2207	Transcriptional regulator
M3Q_2791	COG0052	Belongs to the universal ribosomal protein uS2 family
M3Q_2792	COG0024	Methionine aminopeptidase
M3Q_2794	COG2223	nitrite transmembrane transporter activity
M3Q_2797	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M3Q_2798	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
M3Q_2799	COG1960	acyl-CoA dehydrogenase activity
M3Q_28	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M3Q_2802	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
M3Q_2803	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
M3Q_2804	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M3Q_2808	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M3Q_2809	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
M3Q_2810	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M3Q_2814	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
M3Q_2817	COG3104	oligopeptide transport
M3Q_2819	COG0512	Glutamine amidotransferase of anthranilate synthase
M3Q_2820	COG0308	aminopeptidase N
M3Q_2826	COG1529	Aldehyde oxidase and xanthine dehydrogenase
M3Q_283	COG1596	polysaccharide export
M3Q_2834	COG3739	integral membrane protein
M3Q_2837	COG1169	isochorismate synthase
M3Q_2839	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
M3Q_284	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
M3Q_2841	COG1132	(ABC) transporter
M3Q_2844	COG3433	isochorismatase activity
M3Q_2844	COG1535	isochorismatase
M3Q_2845	COG1021	2,3-dihydroxybenzoate-AMP ligase
M3Q_2846	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M3Q_2848	COG4774	siderophore transport
M3Q_2849	COG4607	ABC-type enterochelin transport system periplasmic component
M3Q_2850	COG4604	ABC transporter, ATP-binding protein
M3Q_2851	COG4605	iron ion homeostasis
M3Q_2852	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M3Q_2855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M3Q_2858	COG2964	Protein conserved in bacteria
M3Q_286	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
M3Q_2861	COG1741	Belongs to the pirin family
M3Q_2864	COG1309	transcriptional regulator
M3Q_2866	COG4948	Mandelate Racemase Muconate Lactonizing
M3Q_2867	COG2814	Major facilitator Superfamily
M3Q_2874	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
M3Q_2874	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M3Q_2875	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M3Q_2878	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M3Q_2879	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M3Q_2880	COG0583	DNA-binding transcription factor activity
M3Q_2881	COG1113	amino acid transport
M3Q_2885	COG2508	Transcriptional regulator
M3Q_2885	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
M3Q_289	COG2030	dehydratase
M3Q_2891	COG2879	small protein
M3Q_2892	COG1966	Carbon starvation protein
M3Q_2910	COG4695	Portal protein
M3Q_2911	COG4626	Terminase
M3Q_2911	COG1802	Transcriptional regulator
M3Q_292	COG1216	Glycosyl transferase, family 2
M3Q_293	COG0438	transferase activity, transferring glycosyl groups
M3Q_2931	COG2879	small protein
M3Q_2932	COG1966	Carbon starvation protein
M3Q_2941	COG1067	ATP-dependent peptidase activity
M3Q_2942	COG0583	DNA-binding transcription factor activity
M3Q_2947	COG1686	Belongs to the peptidase S11 family
M3Q_2948	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
M3Q_2955	COG0616	signal peptide processing
M3Q_2956	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
M3Q_2958	COG0573	inorganic phosphate transmembrane transporter activity
M3Q_2959	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M3Q_296	COG1216	Glycosyl transferase, family 2
M3Q_2960	COG1113	amino acid transport
M3Q_2961	COG3961	Belongs to the TPP enzyme family
M3Q_2962	COG1522	sequence-specific DNA binding
M3Q_2964	COG0076	glutamate decarboxylase activity
M3Q_2965	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M3Q_2967	COG1309	transcriptional regulator
M3Q_297	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
M3Q_2970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M3Q_2977	COG0352	thiamine-phosphate diphosphorylase activity
M3Q_298	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M3Q_2982	COG0612	Peptidase, M16
M3Q_2985	COG0583	DNA-binding transcription factor activity
M3Q_2986	COG0477	Major facilitator Superfamily
M3Q_2990	COG1187	pseudouridine synthase activity
M3Q_2993	COG1686	Belongs to the peptidase S11 family
M3Q_2994	COG1252	NADH dehydrogenase
M3Q_2996	COG0415	Belongs to the DNA photolyase family
M3Q_2999	COG1215	transferase activity, transferring glycosyl groups
M3Q_30	COG3706	GGDEF domain
M3Q_3005	COG2070	2-Nitropropane dioxygenase
M3Q_301	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M3Q_3016	COG0556	nucleotide-excision repair
M3Q_3024	COG4221	oxidoreductase activity
M3Q_3026	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
M3Q_3027	COG1381	Involved in DNA repair and RecF pathway recombination
M3Q_3029	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
M3Q_303	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M3Q_3032	COG0681	Belongs to the peptidase S26 family
M3Q_3035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M3Q_3039	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
M3Q_3040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M3Q_3041	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
M3Q_3043	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
M3Q_3044	COG4208	sulfate ABC transporter
M3Q_3045	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
M3Q_3046	COG0583	DNA-binding transcription factor activity
M3Q_3047	COG4625	pathogenesis
M3Q_305	COG2186	Transcriptional regulator
M3Q_3050	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
M3Q_3053	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
M3Q_3055	COG1051	belongs to the nudix hydrolase family
M3Q_3055	COG1056	cytidyltransferase-related domain
M3Q_3056	COG1024	Enoyl-CoA hydratase
M3Q_3057	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
M3Q_3059	COG2814	Major facilitator Superfamily
M3Q_3060	COG0047	phosphoribosylformylglycinamidine synthase activity
M3Q_3060	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
M3Q_3064	COG1473	amidohydrolase
M3Q_3065	COG0824	Thioesterase
M3Q_3069	COG0823	Involved in the tonB-independent uptake of proteins
M3Q_307	COG0277	FAD linked oxidase domain protein
M3Q_3073	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M3Q_308	COG1448	Aminotransferase
M3Q_3080	COG0628	permease
M3Q_3082	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
M3Q_3083	COG0596	Alpha beta hydrolase
M3Q_3084	COG0616	signal peptide processing
M3Q_3084	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
M3Q_3086	COG0658	competence protein
M3Q_3086	COG2333	competence protein COMEC
M3Q_3087	COG1136	(ABC) transporter
M3Q_3088	COG4591	ABC-type transport system involved in lipoprotein release permease component
M3Q_309	COG1802	Transcriptional regulator
M3Q_3095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M3Q_3099	COG0463	Glycosyl transferase, family 2
M3Q_3105	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
M3Q_3106	COG1280	lysine exporter protein (LysE YggA)
M3Q_3108	COG0019	diaminopimelate decarboxylase activity
M3Q_3110	COG1113	amino acid transport
M3Q_3113	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
M3Q_3115	COG3339	Conserved Protein
M3Q_3116	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
M3Q_3117	COG0243	molybdopterin cofactor binding
M3Q_3118	COG1929	Belongs to the glycerate kinase type-1 family
M3Q_312	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
M3Q_3121	COG0778	Nitroreductase
M3Q_3126	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M3Q_3128	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
M3Q_3132	COG0741	lytic transglycosylase activity
M3Q_3136	COG0584	glycerophosphoryl diester phosphodiesterase
M3Q_3142	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
M3Q_3146	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
M3Q_3147	COG0477	Major facilitator Superfamily
M3Q_3154	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
M3Q_3155	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M3Q_3160	COG0505	Belongs to the CarA family
M3Q_3164	COG0589	response to stress
M3Q_3167	COG2843	Capsule synthesis protein
M3Q_3173	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
M3Q_3181	COG2321	neutral zinc metallopeptidase
M3Q_3182	COG2354	Protein conserved in bacteria
M3Q_3186	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M3Q_3189	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
M3Q_3190	COG1053	succinate dehydrogenase
M3Q_3191	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
M3Q_3192	COG2009	succinate dehydrogenase
M3Q_32	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M3Q_3200	COG2921	Belongs to the UPF0250 family
M3Q_3201	COG0321	lipoyl(octanoyl) transferase activity
M3Q_3204	COG0531	amino acid
M3Q_3206	COG1733	regulation of RNA biosynthetic process
M3Q_3207	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
M3Q_3208	COG1648	precorrin-2 dehydrogenase activity
M3Q_3208	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
M3Q_3211	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
M3Q_3216	COG0671	phosphoesterase, PA-phosphatase related
M3Q_3217	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M3Q_3219	COG1538	Outer membrane efflux protein
M3Q_3220	COG0393	Putative heavy-metal-binding
M3Q_3221	COG0393	Putative heavy-metal-binding
M3Q_3223	COG1028	Short-chain dehydrogenase reductase Sdr
M3Q_3225	COG0525	valine-tRNA ligase activity
M3Q_3229	COG0583	DNA-binding transcription factor activity
M3Q_323	COG0564	pseudouridine synthase activity
M3Q_3230	COG0004	ammonium transporteR
M3Q_3232	COG0642	Histidine kinase
M3Q_3233	COG0745	RESPONSE REGULATOR receiver
M3Q_3234	COG2194	sulfuric ester hydrolase activity
M3Q_3238	COG1752	Esterase of the alpha-beta hydrolase superfamily
M3Q_3241	COG2315	Protein conserved in bacteria
M3Q_3242	COG0142	geranyltranstransferase activity
M3Q_3243	COG2828	Protein conserved in bacteria
M3Q_3244	COG1113	amino acid transport
M3Q_3247	COG2207	Transcriptional regulator
M3Q_3252	COG2249	NAD(P)H dehydrogenase (quinone) activity
M3Q_3256	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M3Q_3258	COG1530	ribonuclease E activity
M3Q_3259	COG0424	maF-like protein
M3Q_3260	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
M3Q_3261	COG1792	Involved in formation and maintenance of cell shape
M3Q_3262	COG1077	Cell shape determining protein MreB Mrl
M3Q_3263	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
M3Q_3265	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
M3Q_3271	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
M3Q_3272	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
M3Q_3273	COG1752	Esterase of the alpha-beta hydrolase superfamily
M3Q_3274	COG1115	amino acid carrier protein
M3Q_3277	COG2814	Major facilitator Superfamily
M3Q_3278	COG1289	transmembrane transporter activity
M3Q_328	COG1522	sequence-specific DNA binding
M3Q_3282	COG1376	ErfK ybiS ycfS ynhG family protein
M3Q_3283	COG2832	Protein of unknown function (DUF454)
M3Q_3285	COG5510	response to toxic substance
M3Q_3289	COG0840	transmembrane signaling receptor activity
M3Q_3297	COG3422	double-strand break repair
M3Q_3298	COG2824	Alkylphosphonate utilization operon protein PhnA
M3Q_3299	COG3189	MarR family transcriptional regulator
M3Q_3301	COG0354	folic acid binding
M3Q_3302	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M3Q_3305	COG1902	pentaerythritol trinitrate reductase activity
M3Q_3306	COG4772	TonB-dependent receptor
M3Q_3308	COG2321	neutral zinc metallopeptidase
M3Q_3309	COG2354	Protein conserved in bacteria
M3Q_331	COG0251	oxidation-reduction process
M3Q_3313	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M3Q_3316	COG2094	Belongs to the DNA glycosylase MPG family
M3Q_332	COG1113	amino acid transport
M3Q_3322	COG2233	PERMEase
M3Q_3324	COG0833	amino acid
M3Q_3325	COG1690	Belongs to the RtcB family
M3Q_3327	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
M3Q_3327	COG2885	chlorophyll binding
M3Q_3329	COG0183	Belongs to the thiolase family
M3Q_333	COG1113	amino acid transport
M3Q_3333	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M3Q_3337	COG2207	Transcriptional regulator
M3Q_3338	COG0183	Belongs to the thiolase family
M3Q_3345	COG1272	protein, Hemolysin III
M3Q_3346	COG0477	Major facilitator Superfamily
M3Q_3349	COG0450	alkyl hydroperoxide reductase
M3Q_3353	COG0285	dihydrofolate synthase activity
M3Q_3360	COG0133	tryptophan synthase activity
M3Q_3363	COG2096	Adenosyltransferase
M3Q_3367	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
M3Q_3368	COG0745	RESPONSE REGULATOR receiver
M3Q_3369	COG2205	protein histidine kinase activity
M3Q_337	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M3Q_3371	COG1960	acyl-CoA dehydrogenase activity
M3Q_3372	COG1960	acyl-CoA dehydrogenase activity
M3Q_3373	COG0583	DNA-binding transcription factor activity
M3Q_3374	COG0625	glutathione transferase activity
M3Q_338	COG1960	acyl-CoA dehydrogenase activity
M3Q_3387	COG0438	transferase activity, transferring glycosyl groups
M3Q_3388	COG0463	Glycosyl transferase, family 2
M3Q_3389	COG0726	polysaccharide deacetylase
M3Q_339	COG1024	Enoyl-CoA hydratase
M3Q_3393	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
M3Q_3394	COG2205	protein histidine kinase activity
M3Q_3399	COG1862	Preprotein translocase
M3Q_34	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M3Q_340	COG1024	Enoyl-CoA hydratase
M3Q_3401	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M3Q_3402	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M3Q_3404	COG3781	membrane
M3Q_3405	COG0613	PHP domain protein
M3Q_3407	COG2350	Protein conserved in bacteria
M3Q_341	COG0477	Major facilitator Superfamily
M3Q_3413	COG1607	acyl-coa hydrolase
M3Q_3416	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M3Q_3416	COG3453	Protein conserved in bacteria
M3Q_342	COG3916	Acyl-homoserine-lactone synthase
M3Q_3420	COG2199	diguanylate cyclase activity
M3Q_3422	COG1408	metallophosphoesterase
M3Q_3423	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M3Q_3425	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
M3Q_3429	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
M3Q_3430	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
M3Q_3433	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
M3Q_3435	COG2969	positive regulation of protein catabolic process
M3Q_3439	COG1960	acyl-CoA dehydrogenase activity
M3Q_344	COG2197	response regulator
M3Q_3440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
M3Q_3443	COG1309	transcriptional regulator
M3Q_3444	COG1960	acyl-CoA dehydrogenase activity
M3Q_3448	COG1183	phosphatidylcholine synthase activity
M3Q_3449	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
M3Q_3455	COG0741	lytic transglycosylase activity
M3Q_3455	COG0739	heme binding
M3Q_3455	COG1196	nuclear chromosome segregation
M3Q_3457	COG1702	phosphate starvation-inducible protein PhoH
M3Q_346	COG1960	acyl-CoA dehydrogenase activity
M3Q_3464	COG1295	ribonuclease BN
M3Q_3465	COG0697	spore germination
M3Q_3466	COG2169	Transcriptional regulator
M3Q_3467	COG0179	Fumarylacetoacetate (FAA) hydrolase
M3Q_347	COG3321	synthase
M3Q_347	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M3Q_347	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
M3Q_347	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
M3Q_3472	COG0557	exoribonuclease II activity
M3Q_3473	COG0339	signal peptide processing
M3Q_3474	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
M3Q_3481	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
M3Q_3482	COG1960	acyl-CoA dehydrogenase activity
M3Q_3487	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
M3Q_3489	COG0257	Belongs to the bacterial ribosomal protein bL36 family
M3Q_349	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M3Q_35	COG3162	membrane
M3Q_3509	COG0088	Forms part of the polypeptide exit tunnel
M3Q_3513	COG0626	cystathionine gamma-synthase activity
M3Q_3514	COG0433	COG0433 Predicted ATPase
M3Q_3515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M3Q_3515	COG1017	nitric oxide dioxygenase activity
M3Q_3516	COG1959	2 iron, 2 sulfur cluster binding
M3Q_3519	COG1301	dicarboxylic acid transport
M3Q_352	COG2267	carboxylic ester hydrolase activity
M3Q_3520	COG1946	Acyl-CoA thioesterase
M3Q_3524	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
M3Q_3525	COG1040	competence protein
M3Q_3528	COG0598	Magnesium transport protein CorA
M3Q_3530	COG2854	intermembrane phospholipid transfer
M3Q_3532	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
M3Q_3533	COG1127	ABC transporter
M3Q_3534	COG0513	Belongs to the DEAD box helicase family
M3Q_3538	COG0408	coproporphyrinogen oxidase activity
M3Q_354	COG0271	Belongs to the BolA IbaG family
M3Q_3541	COG1960	acyl-CoA dehydrogenase activity
M3Q_3543	COG1983	PspC domain protein
M3Q_3544	COG0517	IMP dehydrogenase activity
M3Q_3553	COG0583	DNA-binding transcription factor activity
M3Q_3561	COG1012	belongs to the aldehyde dehydrogenase family
M3Q_3563	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M3Q_3564	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M3Q_3565	COG0833	amino acid
M3Q_357	COG4399	Belongs to the UPF0754 family
M3Q_357	COG4399	Belongs to the UPF0754 family
M3Q_3572	COG0628	permease
M3Q_3574	COG1289	transmembrane transporter activity
M3Q_3577	COG2249	NAD(P)H dehydrogenase (quinone) activity
M3Q_3578	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
M3Q_358	COG2259	Doxx family
M3Q_3580	COG0277	FAD linked oxidase domain protein
M3Q_3581	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M3Q_3586	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
M3Q_3587	COG5380	lipid catabolic process
M3Q_359	COG0586	Pfam SNARE associated Golgi protein
M3Q_3591	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
M3Q_36	COG2205	protein histidine kinase activity
M3Q_36	COG0784	Response regulator, receiver
M3Q_36	COG2198	Histidine kinase
M3Q_3601	COG0194	GDP metabolic process
M3Q_3603	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M3Q_3607	COG3307	-O-antigen
M3Q_3611	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
M3Q_3612	COG1704	LemA family
M3Q_3614	COG0493	'glutamate synthase
M3Q_3615	COG0070	glutamate synthase
M3Q_3615	COG0067	glutamate synthase
M3Q_3615	COG0069	glutamate synthase activity
M3Q_362	COG1192	Involved in chromosome partitioning
M3Q_3625	COG2226	methyltransferase
M3Q_3628	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
M3Q_3629	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
M3Q_3636	COG0833	amino acid
M3Q_364	COG0271	Belongs to the BolA IbaG family
M3Q_3650	COG0488	(ABC) transporter
M3Q_3652	COG4221	oxidoreductase activity
M3Q_3653	COG0659	secondary active sulfate transmembrane transporter activity
M3Q_3654	COG2183	response to ionizing radiation
M3Q_3657	COG0488	(ABC) transporter
M3Q_3659	COG4221	oxidoreductase activity
M3Q_366	COG2267	carboxylic ester hydrolase activity
M3Q_3660	COG0659	secondary active sulfate transmembrane transporter activity
M3Q_3662	COG0745	RESPONSE REGULATOR receiver
M3Q_3664	COG0427	acetyl-CoA hydrolase
M3Q_3668	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
M3Q_3674	COG2329	Antibiotic biosynthesis monooxygenase
M3Q_3677	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M3Q_3689	COG2249	NAD(P)H dehydrogenase (quinone) activity
M3Q_369	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M3Q_3690	COG1733	regulation of RNA biosynthetic process
M3Q_3696	COG0667	Aldo Keto reductase
M3Q_371	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M3Q_372	COG1121	(ABC) transporter
M3Q_385	COG0386	Belongs to the glutathione peroxidase family
M3Q_388	COG1309	transcriptional regulator
M3Q_389	COG0697	spore germination
M3Q_391	COG0758	DNA mediated transformation
M3Q_398	COG1309	transcriptional regulator
M3Q_4	COG0583	DNA-binding transcription factor activity
M3Q_400	COG0656	L-ascorbic acid biosynthetic process
M3Q_401	COG0583	DNA-binding transcription factor activity
M3Q_403	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M3Q_404	COG1064	alcohol dehydrogenase
M3Q_405	COG2818	Glycosylase
M3Q_408	COG1194	a g-specific adenine glycosylase
M3Q_41	COG3328	transposase activity
M3Q_412	COG2983	Belongs to the UPF0260 family
M3Q_413	COG2133	pyrroloquinoline quinone binding
M3Q_414	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
M3Q_415	COG2116	formate transmembrane transporter activity
M3Q_419	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M3Q_42	COG1522	sequence-specific DNA binding
M3Q_420	COG1335	isochorismatase
M3Q_421	COG0385	Bile acid
M3Q_422	COG0534	Mate efflux family protein
M3Q_423	COG1683	Conserved Protein
M3Q_427	COG0625	glutathione transferase activity
M3Q_43	COG1335	isochorismatase
M3Q_431	COG0318	PFAM AMP-dependent synthetase and ligase
M3Q_434	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
M3Q_438	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M3Q_44	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M3Q_440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M3Q_441	COG0606	chelatase, subunit chli
M3Q_447	COG0589	response to stress
M3Q_448	COG0659	secondary active sulfate transmembrane transporter activity
M3Q_454	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
M3Q_46	COG0668	transmembrane transport
M3Q_465	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M3Q_47	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M3Q_473	COG0589	response to stress
M3Q_474	COG0659	secondary active sulfate transmembrane transporter activity
M3Q_48	COG1519	Transferase
M3Q_484	COG0606	chelatase, subunit chli
M3Q_486	COG0347	Belongs to the P(II) protein family
M3Q_487	COG0004	ammonium transporteR
M3Q_489	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M3Q_489	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M3Q_49	COG1902	pentaerythritol trinitrate reductase activity
M3Q_497	COG0795	lipopolysaccharide-transporting ATPase activity
M3Q_498	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
M3Q_499	COG0793	Belongs to the peptidase S41A family
M3Q_5	COG2814	Major facilitator Superfamily
M3Q_502	COG2197	response regulator
M3Q_504	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
M3Q_506	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M3Q_507	COG4974	Belongs to the 'phage' integrase family
M3Q_512	COG0772	Belongs to the SEDS family
M3Q_513	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
M3Q_514	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
M3Q_515	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
M3Q_520	COG0697	spore germination
M3Q_521	COG1538	Outer membrane efflux protein
M3Q_525	COG3275	phosphorelay sensor kinase activity
M3Q_527	COG0181	hydroxymethylbilane synthase activity
M3Q_536	COG1716	ATPase activity
M3Q_537	COG0546	phosphoglycolate phosphatase activity
M3Q_54	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
M3Q_552	COG0596	Alpha beta hydrolase
M3Q_553	COG2056	Na+-H+ antiporter family
M3Q_556	COG0326	Molecular chaperone. Has ATPase activity
M3Q_559	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
M3Q_572	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
M3Q_573	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M3Q_573	COG2169	Transcriptional regulator
M3Q_579	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
M3Q_581	COG0497	DNA recombination
M3Q_584	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M3Q_586	COG0237	dephospho-CoA kinase activity
M3Q_59	COG0426	domain, Protein
M3Q_59	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M3Q_593	COG0195	Participates in both transcription termination and antitermination
M3Q_597	COG2212	antiporter activity
M3Q_599	COG0651	ATP synthesis coupled electron transport
M3Q_60	COG4774	siderophore transport
M3Q_600	COG1006	Multisubunit Na H antiporter MnhC subunit
M3Q_601	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M3Q_601	COG2111	Na H antiporter
M3Q_604	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
M3Q_605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M3Q_608	COG2226	methyltransferase
M3Q_61	COG2119	membrane
M3Q_612	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
M3Q_613	COG1074	ATP-dependent DNA helicase activity
M3Q_614	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M3Q_618	COG0598	Magnesium transport protein CorA
M3Q_619	COG0789	Transcriptional regulator
M3Q_620	COG0484	heat shock protein binding
M3Q_622	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
M3Q_623	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M3Q_623	COG0475	glutathione-regulated potassium exporter activity
M3Q_624	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
M3Q_628	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M3Q_63	COG0508	dehydrogenase complex catalyzes the overall conversion of
M3Q_630	COG4535	Mg2 and Co2 transporter CorC
M3Q_631	COG0425	Belongs to the sulfur carrier protein TusA family
M3Q_632	COG0644	oxidoreductase
M3Q_632	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
M3Q_634	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
M3Q_637	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M3Q_638	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
M3Q_645	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
M3Q_648	COG0534	Mate efflux family protein
M3Q_65	COG4942	peptidase
M3Q_650	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M3Q_651	COG4221	oxidoreductase activity
M3Q_652	COG0583	DNA-binding transcription factor activity
M3Q_654	COG1530	ribonuclease E activity
M3Q_656	COG0546	phosphoglycolate phosphatase activity
M3Q_657	COG2378	regulation of single-species biofilm formation
M3Q_658	COG0625	glutathione transferase activity
M3Q_660	COG0583	DNA-binding transcription factor activity
M3Q_673	COG0473	3-isopropylmalate dehydrogenase activity
M3Q_68	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
M3Q_684	COG1301	dicarboxylic acid transport
M3Q_686	COG1560	Kdo2-lipid A biosynthetic process
M3Q_687	COG1280	lysine exporter protein (LysE YggA)
M3Q_691	COG1733	regulation of RNA biosynthetic process
M3Q_696	COG0210	DNA helicase
M3Q_697	COG0724	RNA recognition motif
M3Q_70	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
M3Q_701	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M3Q_701	COG4651	solute:proton antiporter activity
M3Q_702	COG0267	Belongs to the bacterial ribosomal protein bL33 family
M3Q_703	COG0227	Belongs to the bacterial ribosomal protein bL28 family
M3Q_706	COG0788	formyltetrahydrofolate deformylase activity
M3Q_726	COG2813	Specifically methylates the guanine in position
M3Q_726	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
M3Q_728	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
M3Q_730	COG4774	siderophore transport
M3Q_732	COG0740	serine-type endopeptidase activity
M3Q_736	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
M3Q_736	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
M3Q_737	COG0280	phosphate acetyltransferase
M3Q_737	COG0857	belongs to the CobB CobQ family
M3Q_738	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
M3Q_74	COG0189	ligase activity
M3Q_740	COG0800	Aldolase
M3Q_742	COG3265	gluconokinase activity
M3Q_743	COG1012	belongs to the aldehyde dehydrogenase family
M3Q_745	COG2267	carboxylic ester hydrolase activity
M3Q_748	COG0793	Belongs to the peptidase S41A family
M3Q_755	COG1426	Protein conserved in bacteria
M3Q_763	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M3Q_764	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M3Q_766	COG0318	PFAM AMP-dependent synthetase and ligase
M3Q_769	COG2986	histidine ammonia-lyase
M3Q_777	COG1028	Short-chain dehydrogenase reductase Sdr
M3Q_778	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M3Q_782	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
M3Q_784	COG1162	GTPase activity
M3Q_785	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
M3Q_788	COG1538	Outer membrane efflux protein
M3Q_789	COG1136	(ABC) transporter
M3Q_789	COG0577	efflux transmembrane transporter activity
M3Q_790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M3Q_795	COG0028	Belongs to the TPP enzyme family
M3Q_796	COG0440	acetolactate synthase activity
M3Q_802	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
M3Q_805	COG0084	hydrolase, TatD family'
M3Q_808	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
M3Q_809	COG0583	DNA-binding transcription factor activity
M3Q_81	COG0708	Exodeoxyribonuclease III
M3Q_811	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M3Q_812	COG2814	Major facilitator Superfamily
M3Q_814	COG0697	spore germination
M3Q_815	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
M3Q_816	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
M3Q_817	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
M3Q_82	COG1393	Belongs to the ArsC family
M3Q_820	COG3622	Belongs to the hyi family
M3Q_821	COG2084	Dehydrogenase
M3Q_822	COG1024	Enoyl-CoA hydratase
M3Q_823	COG0784	Response regulator, receiver
M3Q_823	COG2205	protein histidine kinase activity
M3Q_823	COG5002	protein histidine kinase activity
M3Q_827	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M3Q_829	COG3956	TIGRFAM MazG family protein
M3Q_830	COG1555	photosystem II stabilization
M3Q_831	COG0617	tRNA 3'-terminal CCA addition
M3Q_832	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
M3Q_836	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M3Q_837	COG3028	Belongs to the UPF0307 family
M3Q_838	COG0318	PFAM AMP-dependent synthetase and ligase
M3Q_841	COG0625	glutathione transferase activity
M3Q_842	COG1238	metal cluster binding
M3Q_845	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
M3Q_85	COG3706	GGDEF domain
M3Q_850	COG0072	phenylalanine-tRNA ligase activity
M3Q_855	COG0248	Ppx GppA phosphatase
M3Q_857	COG0037	tRNA processing
M3Q_865	COG1764	response to oxidative stress
M3Q_866	COG1846	Transcriptional regulator
M3Q_868	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M3Q_875	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
M3Q_876	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
M3Q_877	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
M3Q_879	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
M3Q_889	COG1214	PFAM Peptidase M22, glycoprotease
M3Q_894	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
M3Q_895	COG0561	phosphatase activity
M3Q_897	COG2132	Multicopper oxidase
M3Q_898	COG3667	copper resistance
M3Q_901	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M3Q_902	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
M3Q_903	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
M3Q_905	COG1063	alcohol dehydrogenase
M3Q_906	COG0583	DNA-binding transcription factor activity
M3Q_907	COG1960	acyl-CoA dehydrogenase activity
M3Q_908	COG2814	Major facilitator Superfamily
M3Q_909	COG1804	L-carnitine dehydratase bile acid-inducible protein F
M3Q_911	COG1053	succinate dehydrogenase
M3Q_915	COG0583	DNA-binding transcription factor activity
M3Q_917	COG1473	amidohydrolase
M3Q_92	COG2351	hydroxyisourate hydrolase activity
M3Q_921	COG0583	DNA-binding transcription factor activity
M3Q_923	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
M3Q_924	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M3Q_929	COG0384	phenazine biosynthesis protein PhzF
M3Q_93	COG2233	PERMEase
M3Q_933	COG4993	Dehydrogenase
M3Q_947	COG2205	protein histidine kinase activity
M3Q_948	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M3Q_95	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M3Q_951	COG0745	RESPONSE REGULATOR receiver
M3Q_952	COG2205	protein histidine kinase activity
M3Q_959	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
M3Q_965	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M3Q_966	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M3Q_97	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
M3Q_970	COG0583	DNA-binding transcription factor activity
M3Q_974	COG0668	transmembrane transport
M3Q_976	COG2081	HI0933 family
M3Q_977	COG2515	1-aminocyclopropane-1-carboxylate deaminase
M3Q_98	COG1028	Short-chain dehydrogenase reductase Sdr
M3Q_983	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M3Q_983	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M3Q_985	COG0489	protein tyrosine kinase activity
M3Q_995	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M3Q_997	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY