locus-tag	class	description
KQ254_00020	COG0440	acetolactate synthase activity
KQ254_00025	COG0028	Belongs to the TPP enzyme family
KQ254_00050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KQ254_00055	COG0577	efflux transmembrane transporter activity
KQ254_00055	COG1136	(ABC) transporter
KQ254_00060	COG1538	Outer membrane efflux protein
KQ254_00075	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KQ254_00080	COG1162	GTPase activity
KQ254_00090	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KQ254_00130	COG1426	Protein conserved in bacteria
KQ254_00165	COG0793	Belongs to the peptidase S41A family
KQ254_00180	COG2267	carboxylic ester hydrolase activity
KQ254_00190	COG1012	belongs to the aldehyde dehydrogenase family
KQ254_00195	COG3265	gluconokinase activity
KQ254_00205	COG0800	Aldolase
KQ254_00215	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KQ254_00220	COG0280	phosphate acetyltransferase
KQ254_00220	COG0857	belongs to the CobB CobQ family
KQ254_00225	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KQ254_00225	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KQ254_00245	COG0740	serine-type endopeptidase activity
KQ254_00255	COG4774	siderophore transport
KQ254_00265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KQ254_00275	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KQ254_00275	COG2813	Specifically methylates the guanine in position
KQ254_00375	COG0788	formyltetrahydrofolate deformylase activity
KQ254_00400	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KQ254_00400	COG4651	solute:proton antiporter activity
KQ254_00420	COG0724	RNA recognition motif
KQ254_00425	COG0210	DNA helicase
KQ254_00450	COG1733	regulation of RNA biosynthetic process
KQ254_00460	COG2900	Belongs to the SlyX family
KQ254_00465	COG0488	(ABC) transporter
KQ254_00470	COG1280	lysine exporter protein (LysE YggA)
KQ254_00475	COG1560	Kdo2-lipid A biosynthetic process
KQ254_00485	COG1301	dicarboxylic acid transport
KQ254_00540	COG0473	3-isopropylmalate dehydrogenase activity
KQ254_00595	COG0583	DNA-binding transcription factor activity
KQ254_00605	COG0625	glutathione transferase activity
KQ254_00610	COG2378	regulation of single-species biofilm formation
KQ254_00615	COG0546	phosphoglycolate phosphatase activity
KQ254_00625	COG1530	ribonuclease E activity
KQ254_00630	COG0318	PFAM AMP-dependent synthetase and ligase
KQ254_00645	COG0583	DNA-binding transcription factor activity
KQ254_00650	COG4221	oxidoreductase activity
KQ254_00655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KQ254_00665	COG0534	Mate efflux family protein
KQ254_00680	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KQ254_00710	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
KQ254_00710	COG0493	'glutamate synthase
KQ254_00720	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KQ254_00725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KQ254_00740	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KQ254_00750	COG0644	oxidoreductase
KQ254_00750	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
KQ254_00755	COG0425	Belongs to the sulfur carrier protein TusA family
KQ254_00760	COG4535	Mg2 and Co2 transporter CorC
KQ254_00770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KQ254_00790	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KQ254_00795	COG0475	glutathione-regulated potassium exporter activity
KQ254_00795	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KQ254_00810	COG0484	heat shock protein binding
KQ254_00815	COG0789	Transcriptional regulator
KQ254_00820	COG0598	Magnesium transport protein CorA
KQ254_00835	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KQ254_00840	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KQ254_00845	COG1074	ATP-dependent DNA helicase activity
KQ254_00850	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KQ254_00870	COG2226	methyltransferase
KQ254_00885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KQ254_00890	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KQ254_00905	COG2111	Na H antiporter
KQ254_00905	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KQ254_00910	COG1006	Multisubunit Na H antiporter MnhC subunit
KQ254_00915	COG0651	ATP synthesis coupled electron transport
KQ254_00920	COG1863	multisubunit Na H antiporter MnhE subunit
KQ254_00925	COG2212	antiporter activity
KQ254_00930	COG1320	monovalent cation:proton antiporter activity
KQ254_00945	COG0195	Participates in both transcription termination and antitermination
KQ254_00995	COG0237	dephospho-CoA kinase activity
KQ254_01005	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KQ254_01020	COG0497	DNA recombination
KQ254_01030	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KQ254_01060	COG2169	Transcriptional regulator
KQ254_01060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KQ254_01065	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KQ254_01120	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KQ254_01135	COG0326	Molecular chaperone. Has ATPase activity
KQ254_01150	COG2056	Na+-H+ antiporter family
KQ254_01250	COG0546	phosphoglycolate phosphatase activity
KQ254_01255	COG1716	ATPase activity
KQ254_01300	COG0181	hydroxymethylbilane synthase activity
KQ254_01310	COG3275	phosphorelay sensor kinase activity
KQ254_01330	COG1538	Outer membrane efflux protein
KQ254_01335	COG0697	spore germination
KQ254_01360	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KQ254_01365	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KQ254_01370	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KQ254_01375	COG0772	Belongs to the SEDS family
KQ254_01400	COG4974	Belongs to the 'phage' integrase family
KQ254_01405	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KQ254_01415	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KQ254_01425	COG2197	response regulator
KQ254_01440	COG0793	Belongs to the peptidase S41A family
KQ254_01445	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KQ254_01450	COG0795	lipopolysaccharide-transporting ATPase activity
KQ254_01490	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KQ254_01490	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KQ254_01500	COG0004	ammonium transporteR
KQ254_01505	COG0347	Belongs to the P(II) protein family
KQ254_01515	COG0606	chelatase, subunit chli
KQ254_01575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KQ254_01580	COG0235	Class ii aldolase
KQ254_01585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KQ254_01600	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KQ254_01615	COG0318	PFAM AMP-dependent synthetase and ligase
KQ254_01625	COG0477	Major facilitator Superfamily
KQ254_01630	COG2860	membrane
KQ254_01640	COG1253	flavin adenine dinucleotide binding
KQ254_01650	COG2814	Major facilitator Superfamily
KQ254_01660	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KQ254_01695	COG0655	NAD(P)H dehydrogenase (quinone) activity
KQ254_01705	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KQ254_01740	COG1309	transcriptional regulator
KQ254_01775	COG0758	DNA mediated transformation
KQ254_01785	COG0697	spore germination
KQ254_01790	COG1309	transcriptional regulator
KQ254_01805	COG0386	Belongs to the glutathione peroxidase family
KQ254_01875	COG1121	(ABC) transporter
KQ254_01880	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KQ254_01885	COG1280	lysine exporter protein (LysE YggA)
KQ254_01890	COG2837	iron assimilation
KQ254_01900	COG0281	malic enzyme
KQ254_01945	COG0519	Catalyzes the synthesis of GMP from XMP
KQ254_01945	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KQ254_01950	COG4399	Belongs to the UPF0754 family
KQ254_01955	COG2259	Doxx family
KQ254_01960	COG0586	Pfam SNARE associated Golgi protein
KQ254_01975	COG1192	Involved in chromosome partitioning
KQ254_01985	COG0271	Belongs to the BolA IbaG family
KQ254_02025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KQ254_02025	COG3321	synthase
KQ254_02025	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KQ254_02025	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KQ254_02030	COG1960	acyl-CoA dehydrogenase activity
KQ254_02040	COG2197	response regulator
KQ254_02050	COG3916	Acyl-homoserine-lactone synthase
KQ254_02055	COG0477	Major facilitator Superfamily
KQ254_02060	COG1024	Enoyl-CoA hydratase
KQ254_02065	COG1024	Enoyl-CoA hydratase
KQ254_02070	COG1960	acyl-CoA dehydrogenase activity
KQ254_02075	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KQ254_02095	COG1113	amino acid transport
KQ254_02100	COG1113	amino acid transport
KQ254_02105	COG0251	oxidation-reduction process
KQ254_02145	COG0564	pseudouridine synthase activity
KQ254_02190	COG1051	belongs to the nudix hydrolase family
KQ254_02210	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KQ254_02225	COG1802	Transcriptional regulator
KQ254_02235	COG1448	Aminotransferase
KQ254_02240	COG0277	FAD linked oxidase domain protein
KQ254_02250	COG2186	Transcriptional regulator
KQ254_02260	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KQ254_02265	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KQ254_02280	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KQ254_02285	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KQ254_02290	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KQ254_02345	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KQ254_02350	COG1596	polysaccharide export
KQ254_02375	COG0728	peptidoglycan biosynthetic process
KQ254_02380	COG3023	N-Acetylmuramoyl-L-alanine amidase
KQ254_02435	COG0546	phosphoglycolate phosphatase activity
KQ254_02440	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_02460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KQ254_02465	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KQ254_02470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KQ254_02475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KQ254_02480	COG1116	anion transmembrane transporter activity
KQ254_02485	COG1309	transcriptional regulator
KQ254_02490	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KQ254_02500	COG0196	riboflavin kinase activity
KQ254_02505	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KQ254_02515	COG1047	Peptidyl-prolyl cis-trans
KQ254_02555	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KQ254_02560	COG0657	acetylesterase activity
KQ254_02610	COG2951	lytic endotransglycosylase activity
KQ254_02615	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KQ254_02630	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KQ254_02640	COG3328	transposase activity
KQ254_02650	COG0671	phosphoesterase, PA-phosphatase related
KQ254_02655	COG0861	Integral membrane protein TerC family
KQ254_02665	COG0754	glutathionylspermidine amidase activity
KQ254_02675	COG0402	S-adenosylhomocysteine deaminase activity
KQ254_02690	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KQ254_02695	COG1230	cation diffusion facilitator family transporter
KQ254_02710	COG0706	membrane insertase activity
KQ254_02735	COG0592	DNA-directed DNA polymerase activity
KQ254_02745	COG0187	DNA topoisomerase II activity
KQ254_02765	COG0586	Pfam SNARE associated Golgi protein
KQ254_02770	COG0488	(ABC) transporter
KQ254_02795	COG0596	Alpha beta hydrolase
KQ254_02800	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KQ254_02805	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KQ254_02845	COG0733	neurotransmitter:sodium symporter activity
KQ254_02880	COG0583	DNA-binding transcription factor activity
KQ254_02885	COG2233	PERMEase
KQ254_02900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KQ254_02935	COG2814	Major facilitator Superfamily
KQ254_02940	COG0656	L-ascorbic acid biosynthetic process
KQ254_02945	COG0583	DNA-binding transcription factor activity
KQ254_02960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KQ254_02965	COG1064	alcohol dehydrogenase
KQ254_02970	COG2818	Glycosylase
KQ254_02985	COG1194	a g-specific adenine glycosylase
KQ254_03005	COG2983	Belongs to the UPF0260 family
KQ254_03010	COG2133	pyrroloquinoline quinone binding
KQ254_03015	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KQ254_03020	COG2116	formate transmembrane transporter activity
KQ254_03040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KQ254_03045	COG1335	isochorismatase
KQ254_03050	COG0385	Bile acid
KQ254_03055	COG0534	Mate efflux family protein
KQ254_03060	COG1683	Conserved Protein
KQ254_03080	COG0625	glutathione transferase activity
KQ254_03090	COG1113	amino acid transport
KQ254_03100	COG0523	cobalamin synthesis protein
KQ254_03110	COG2188	Transcriptional regulator
KQ254_03140	COG0010	Belongs to the arginase family
KQ254_03155	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KQ254_03245	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KQ254_03255	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KQ254_03260	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KQ254_03345	COG0534	Mate efflux family protein
KQ254_03350	COG0436	Aminotransferase
KQ254_03355	COG2733	membrane
KQ254_03370	COG2918	glutathione biosynthetic process
KQ254_03405	COG3150	esterase
KQ254_03415	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_03420	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
KQ254_03430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KQ254_03440	COG2233	PERMEase
KQ254_03445	COG2351	hydroxyisourate hydrolase activity
KQ254_03480	COG3706	GGDEF domain
KQ254_03495	COG1393	Belongs to the ArsC family
KQ254_03500	COG0708	Exodeoxyribonuclease III
KQ254_03520	COG0189	ligase activity
KQ254_03540	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KQ254_03550	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KQ254_03565	COG4942	peptidase
KQ254_03575	COG0508	dehydrogenase complex catalyzes the overall conversion of
KQ254_03585	COG2119	membrane
KQ254_03590	COG4774	siderophore transport
KQ254_03595	COG0426	domain, Protein
KQ254_03595	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KQ254_03620	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KQ254_03640	COG1902	pentaerythritol trinitrate reductase activity
KQ254_03645	COG1519	Transferase
KQ254_03650	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KQ254_03655	COG0668	transmembrane transport
KQ254_03665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KQ254_03670	COG1335	isochorismatase
KQ254_03675	COG1522	sequence-specific DNA binding
KQ254_03700	COG0784	Response regulator, receiver
KQ254_03700	COG2198	Histidine kinase
KQ254_03700	COG2205	protein histidine kinase activity
KQ254_03705	COG3162	membrane
KQ254_03710	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KQ254_03720	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KQ254_03740	COG1309	transcriptional regulator
KQ254_03760	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KQ254_03760	COG0352	thiamine-phosphate diphosphorylase activity
KQ254_03760	COG0351	phosphomethylpyrimidine kinase
KQ254_03770	COG2814	Major facilitator Superfamily
KQ254_03785	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KQ254_03795	COG1113	amino acid transport
KQ254_03805	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KQ254_03810	COG1012	belongs to the aldehyde dehydrogenase family
KQ254_03820	COG1335	isochorismatase
KQ254_03850	COG2814	Major facilitator Superfamily
KQ254_03855	COG0583	DNA-binding transcription factor activity
KQ254_03875	COG0667	Aldo Keto reductase
KQ254_03915	COG1733	regulation of RNA biosynthetic process
KQ254_03920	COG2249	NAD(P)H dehydrogenase (quinone) activity
KQ254_03990	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KQ254_04005	COG2329	Antibiotic biosynthesis monooxygenase
KQ254_04040	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KQ254_04070	COG0427	acetyl-CoA hydrolase
KQ254_04095	COG0659	secondary active sulfate transmembrane transporter activity
KQ254_04100	COG4221	oxidoreductase activity
KQ254_04105	COG2873	o-acetylhomoserine
KQ254_04110	COG0488	(ABC) transporter
KQ254_04175	COG0833	amino acid
KQ254_04220	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KQ254_04225	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KQ254_04240	COG2226	methyltransferase
KQ254_04290	COG0070	glutamate synthase
KQ254_04290	COG0069	glutamate synthase activity
KQ254_04290	COG0067	glutamate synthase
KQ254_04295	COG0493	'glutamate synthase
KQ254_04305	COG1704	LemA family
KQ254_04310	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KQ254_04330	COG3307	-O-antigen
KQ254_04350	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KQ254_04365	COG0194	GDP metabolic process
KQ254_04380	COG4969	Belongs to the N-Me-Phe pilin family
KQ254_04420	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KQ254_04440	COG5380	lipid catabolic process
KQ254_04445	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KQ254_04470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KQ254_04475	COG0277	FAD linked oxidase domain protein
KQ254_04485	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KQ254_04490	COG2249	NAD(P)H dehydrogenase (quinone) activity
KQ254_04505	COG1289	transmembrane transporter activity
KQ254_04515	COG0628	permease
KQ254_04550	COG2826	transposase and inactivated derivatives, IS30 family
KQ254_04575	COG3621	Patatin-like phospholipase
KQ254_04620	COG2226	methyltransferase
KQ254_04630	COG0833	amino acid
KQ254_04635	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KQ254_04640	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KQ254_04650	COG1012	belongs to the aldehyde dehydrogenase family
KQ254_04690	COG0583	DNA-binding transcription factor activity
KQ254_04740	COG0517	IMP dehydrogenase activity
KQ254_04745	COG1983	PspC domain protein
KQ254_04755	COG1960	acyl-CoA dehydrogenase activity
KQ254_04770	COG0408	coproporphyrinogen oxidase activity
KQ254_04790	COG0513	Belongs to the DEAD box helicase family
KQ254_04800	COG1127	ABC transporter
KQ254_04805	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KQ254_04815	COG2854	intermembrane phospholipid transfer
KQ254_04825	COG0598	Magnesium transport protein CorA
KQ254_04835	COG0494	nUDIX hydrolase
KQ254_04840	COG1040	competence protein
KQ254_04845	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KQ254_04865	COG1946	Acyl-CoA thioesterase
KQ254_04870	COG1301	dicarboxylic acid transport
KQ254_04885	COG1959	2 iron, 2 sulfur cluster binding
KQ254_04890	COG1017	nitric oxide dioxygenase activity
KQ254_04890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KQ254_04900	COG0433	COG0433 Predicted ATPase
KQ254_04905	COG0626	cystathionine gamma-synthase activity
KQ254_05060	COG1960	acyl-CoA dehydrogenase activity
KQ254_05065	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KQ254_05095	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KQ254_05115	COG0557	exoribonuclease II activity
KQ254_05160	COG0179	Fumarylacetoacetate (FAA) hydrolase
KQ254_05165	COG2169	Transcriptional regulator
KQ254_05175	COG1295	ribonuclease BN
KQ254_05210	COG1702	phosphate starvation-inducible protein PhoH
KQ254_05220	COG0739	heme binding
KQ254_05220	COG0741	lytic transglycosylase activity
KQ254_05220	COG1196	nuclear chromosome segregation
KQ254_05250	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KQ254_05255	COG1183	phosphatidylcholine synthase activity
KQ254_05300	COG1960	acyl-CoA dehydrogenase activity
KQ254_05305	COG1309	transcriptional regulator
KQ254_05320	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KQ254_05325	COG1960	acyl-CoA dehydrogenase activity
KQ254_05345	COG2969	positive regulation of protein catabolic process
KQ254_05355	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KQ254_05370	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KQ254_05375	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KQ254_05395	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KQ254_05405	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KQ254_05410	COG1408	metallophosphoesterase
KQ254_05420	COG2199	diguanylate cyclase activity
KQ254_05480	COG1607	acyl-coa hydrolase
KQ254_05510	COG2350	Protein conserved in bacteria
KQ254_05520	COG0613	PHP domain protein
KQ254_05525	COG3781	membrane
KQ254_05535	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KQ254_05540	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KQ254_05550	COG1862	Preprotein translocase
KQ254_05580	COG0582	viral genome integration into host DNA
KQ254_05600	COG2826	transposase and inactivated derivatives, IS30 family
KQ254_05610	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KQ254_05630	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KQ254_05640	COG2205	protein histidine kinase activity
KQ254_05645	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KQ254_05665	COG0726	polysaccharide deacetylase
KQ254_05670	COG0463	Glycosyl transferase, family 2
KQ254_05675	COG0438	transferase activity, transferring glycosyl groups
KQ254_05740	COG1960	acyl-CoA dehydrogenase activity
KQ254_05745	COG1960	acyl-CoA dehydrogenase activity
KQ254_05755	COG2205	protein histidine kinase activity
KQ254_05760	COG0745	RESPONSE REGULATOR receiver
KQ254_05765	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KQ254_05780	COG0584	glycerophosphoryl diester phosphodiesterase
KQ254_05785	COG2096	Adenosyltransferase
KQ254_05790	COG4206	TonB-dependent receptor
KQ254_05835	COG0285	dihydrofolate synthase activity
KQ254_05855	COG0450	alkyl hydroperoxide reductase
KQ254_05875	COG0477	Major facilitator Superfamily
KQ254_05880	COG1272	protein, Hemolysin III
KQ254_05915	COG0183	Belongs to the thiolase family
KQ254_05920	COG2207	Transcriptional regulator
KQ254_05940	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KQ254_05960	COG0183	Belongs to the thiolase family
KQ254_05970	COG2885	chlorophyll binding
KQ254_05970	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KQ254_06075	COG0833	amino acid
KQ254_06085	COG2233	PERMEase
KQ254_06090	COG1217	gtp-binding protein TYPA
KQ254_06115	COG2094	Belongs to the DNA glycosylase MPG family
KQ254_06120	COG4772	TonB-dependent receptor
KQ254_06125	COG1902	pentaerythritol trinitrate reductase activity
KQ254_06140	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KQ254_06145	COG0354	folic acid binding
KQ254_06160	COG3189	MarR family transcriptional regulator
KQ254_06165	COG2824	Alkylphosphonate utilization operon protein PhnA
KQ254_06170	COG3422	double-strand break repair
KQ254_06210	COG0840	transmembrane signaling receptor activity
KQ254_06230	COG5510	response to toxic substance
KQ254_06240	COG2832	Protein of unknown function (DUF454)
KQ254_06245	COG1376	ErfK ybiS ycfS ynhG family protein
KQ254_06285	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KQ254_06295	COG1289	transmembrane transporter activity
KQ254_06300	COG2814	Major facilitator Superfamily
KQ254_06320	COG1115	amino acid carrier protein
KQ254_06325	COG1752	Esterase of the alpha-beta hydrolase superfamily
KQ254_06330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KQ254_06335	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
KQ254_06340	COG3590	peptidase
KQ254_06365	COG2826	transposase and inactivated derivatives, IS30 family
KQ254_06380	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KQ254_06390	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KQ254_06395	COG1077	Cell shape determining protein MreB Mrl
KQ254_06400	COG1792	Involved in formation and maintenance of cell shape
KQ254_06405	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KQ254_06410	COG0424	maF-like protein
KQ254_06415	COG1530	ribonuclease E activity
KQ254_06425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KQ254_06435	COG0560	Phosphoserine phosphatase
KQ254_06445	COG2249	NAD(P)H dehydrogenase (quinone) activity
KQ254_06470	COG2207	Transcriptional regulator
KQ254_06520	COG1113	amino acid transport
KQ254_06525	COG2828	Protein conserved in bacteria
KQ254_06530	COG0142	geranyltranstransferase activity
KQ254_06535	COG2315	Protein conserved in bacteria
KQ254_06550	COG1752	Esterase of the alpha-beta hydrolase superfamily
KQ254_06570	COG2194	sulfuric ester hydrolase activity
KQ254_06575	COG0745	RESPONSE REGULATOR receiver
KQ254_06580	COG0642	Histidine kinase
KQ254_06590	COG0004	ammonium transporteR
KQ254_06595	COG0583	DNA-binding transcription factor activity
KQ254_06615	COG0525	valine-tRNA ligase activity
KQ254_06625	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_06635	COG0393	Putative heavy-metal-binding
KQ254_06640	COG0393	Putative heavy-metal-binding
KQ254_06645	COG1538	Outer membrane efflux protein
KQ254_06655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KQ254_06660	COG0671	phosphoesterase, PA-phosphatase related
KQ254_06690	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KQ254_06705	COG1648	precorrin-2 dehydrogenase activity
KQ254_06705	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KQ254_06710	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KQ254_06715	COG1733	regulation of RNA biosynthetic process
KQ254_06725	COG0531	amino acid
KQ254_06740	COG0321	lipoyl(octanoyl) transferase activity
KQ254_06745	COG2921	Belongs to the UPF0250 family
KQ254_06780	COG2009	succinate dehydrogenase
KQ254_06785	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KQ254_06790	COG1053	succinate dehydrogenase
KQ254_06795	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KQ254_06820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KQ254_06840	COG2354	Protein conserved in bacteria
KQ254_06845	COG2321	neutral zinc metallopeptidase
KQ254_06865	COG2843	Capsule synthesis protein
KQ254_06880	COG0589	response to stress
KQ254_06890	COG0251	oxidation-reduction process
KQ254_06895	COG1309	transcriptional regulator
KQ254_06910	COG0505	Belongs to the CarA family
KQ254_06935	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KQ254_06940	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KQ254_06990	COG0477	Major facilitator Superfamily
KQ254_06995	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KQ254_07010	COG1597	lipid kinase activity
KQ254_07015	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KQ254_07035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KQ254_07040	COG0584	glycerophosphoryl diester phosphodiesterase
KQ254_07060	COG0741	lytic transglycosylase activity
KQ254_07080	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KQ254_07095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KQ254_07120	COG3811	Belongs to the UPF0386 family
KQ254_07140	COG0778	Nitroreductase
KQ254_07155	COG1929	Belongs to the glycerate kinase type-1 family
KQ254_07160	COG0243	molybdopterin cofactor binding
KQ254_07165	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KQ254_07170	COG3339	Conserved Protein
KQ254_07180	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KQ254_07195	COG1113	amino acid transport
KQ254_07205	COG0019	diaminopimelate decarboxylase activity
KQ254_07215	COG1280	lysine exporter protein (LysE YggA)
KQ254_07220	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KQ254_07250	COG0463	Glycosyl transferase, family 2
KQ254_07270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KQ254_07300	COG4591	ABC-type transport system involved in lipoprotein release permease component
KQ254_07305	COG1136	(ABC) transporter
KQ254_07310	COG0658	competence protein
KQ254_07310	COG2333	competence protein COMEC
KQ254_07320	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KQ254_07320	COG0616	signal peptide processing
KQ254_07325	COG0596	Alpha beta hydrolase
KQ254_07330	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KQ254_07340	COG0628	permease
KQ254_07360	COG2826	transposase and inactivated derivatives, IS30 family
KQ254_07385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KQ254_07405	COG0823	Involved in the tonB-independent uptake of proteins
KQ254_07425	COG0824	Thioesterase
KQ254_07430	COG1473	amidohydrolase
KQ254_07450	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KQ254_07450	COG0047	phosphoribosylformylglycinamidine synthase activity
KQ254_07455	COG2814	Major facilitator Superfamily
KQ254_07465	COG1024	Enoyl-CoA hydratase
KQ254_07470	COG1051	belongs to the nudix hydrolase family
KQ254_07470	COG1056	cytidyltransferase-related domain
KQ254_07480	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KQ254_07495	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KQ254_07510	COG4625	pathogenesis
KQ254_07515	COG0583	DNA-binding transcription factor activity
KQ254_07520	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KQ254_07525	COG4208	sulfate ABC transporter
KQ254_07530	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KQ254_07540	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KQ254_07545	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KQ254_07550	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KQ254_07570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KQ254_07585	COG0681	Belongs to the peptidase S26 family
KQ254_07600	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KQ254_07610	COG1381	Involved in DNA repair and RecF pathway recombination
KQ254_07615	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KQ254_07625	COG4221	oxidoreductase activity
KQ254_07655	COG0436	Aminotransferase
KQ254_07675	COG0556	nucleotide-excision repair
KQ254_07730	COG2070	2-Nitropropane dioxygenase
KQ254_07760	COG1215	transferase activity, transferring glycosyl groups
KQ254_07775	COG0415	Belongs to the DNA photolyase family
KQ254_07785	COG1252	NADH dehydrogenase
KQ254_07805	COG1187	pseudouridine synthase activity
KQ254_07830	COG0477	Major facilitator Superfamily
KQ254_07835	COG0583	DNA-binding transcription factor activity
KQ254_07840	COG1823	symporter activity
KQ254_07850	COG0612	Peptidase, M16
KQ254_07875	COG0352	thiamine-phosphate diphosphorylase activity
KQ254_07910	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KQ254_07920	COG2249	NAD(P)H dehydrogenase (quinone) activity
KQ254_07935	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KQ254_07940	COG0076	glutamate decarboxylase activity
KQ254_07950	COG1522	sequence-specific DNA binding
KQ254_07955	COG3961	Belongs to the TPP enzyme family
KQ254_07960	COG1113	amino acid transport
KQ254_07965	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KQ254_07970	COG0573	inorganic phosphate transmembrane transporter activity
KQ254_07980	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KQ254_07985	COG0616	signal peptide processing
KQ254_08020	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KQ254_08025	COG1686	Belongs to the peptidase S11 family
KQ254_08050	COG0583	DNA-binding transcription factor activity
KQ254_08055	COG1067	ATP-dependent peptidase activity
KQ254_08080	COG4943	cyclic-guanylate-specific phosphodiesterase activity
KQ254_08100	COG1966	Carbon starvation protein
KQ254_08105	COG2879	small protein
KQ254_08115	COG0582	viral genome integration into host DNA
KQ254_08200	COG1741	Belongs to the pirin family
KQ254_08210	COG2964	Protein conserved in bacteria
KQ254_08225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KQ254_08230	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KQ254_08235	COG4605	iron ion homeostasis
KQ254_08240	COG4604	ABC transporter, ATP-binding protein
KQ254_08245	COG4607	ABC-type enterochelin transport system periplasmic component
KQ254_08250	COG4774	siderophore transport
KQ254_08260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KQ254_08265	COG1021	2,3-dihydroxybenzoate-AMP ligase
KQ254_08270	COG1535	isochorismatase
KQ254_08270	COG3433	isochorismatase activity
KQ254_08285	COG1132	(ABC) transporter
KQ254_08290	COG1132	(ABC) transporter
KQ254_08295	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KQ254_08300	COG2977	Belongs to the P-Pant transferase superfamily
KQ254_08320	COG3739	integral membrane protein
KQ254_08355	COG0302	gtp cyclohydrolase
KQ254_08365	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KQ254_08395	COG0308	aminopeptidase N
KQ254_08400	COG0512	Glutamine amidotransferase of anthranilate synthase
KQ254_08415	COG1876	peptidase activity
KQ254_08435	COG0174	glutamine synthetase
KQ254_08445	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KQ254_08480	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KQ254_08485	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KQ254_08490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KQ254_08510	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KQ254_08515	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KQ254_08520	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KQ254_08535	COG1960	acyl-CoA dehydrogenase activity
KQ254_08540	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KQ254_08545	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KQ254_08555	COG2223	nitrite transmembrane transporter activity
KQ254_08565	COG0024	Methionine aminopeptidase
KQ254_08570	COG0052	Belongs to the universal ribosomal protein uS2 family
KQ254_08585	COG2207	Transcriptional regulator
KQ254_08610	COG2951	lytic endotransglycosylase activity
KQ254_08615	COG0772	Belongs to the SEDS family
KQ254_08630	COG0842	Transport permease protein
KQ254_08635	COG1131	(ABC) transporter
KQ254_08640	COG0582	viral genome integration into host DNA
KQ254_08955	COG3561	AntA/AntB antirepressor
KQ254_09045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KQ254_09060	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KQ254_09065	COG0826	peptidase U32
KQ254_09070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KQ254_09085	COG1720	tRNA m6t6A37 methyltransferase activity
KQ254_09095	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KQ254_09110	COG0642	Histidine kinase
KQ254_09120	COG0494	nUDIX hydrolase
KQ254_09130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KQ254_09135	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KQ254_09140	COG3139	Protein of unknown function (DUF1315)
KQ254_09150	COG1301	dicarboxylic acid transport
KQ254_09155	COG1960	acyl-CoA dehydrogenase activity
KQ254_09170	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KQ254_09180	COG2195	Cleaves the N-terminal amino acid of tripeptides
KQ254_09185	COG1234	tRNA 3'-trailer cleavage
KQ254_09215	COG2363	Small membrane protein
KQ254_09235	COG0513	Belongs to the DEAD box helicase family
KQ254_09245	COG0778	Nitroreductase
KQ254_09275	COG1286	toxin biosynthetic process
KQ254_09300	COG4783	chaperone-mediated protein folding
KQ254_09305	COG1610	YqeY-like protein
KQ254_09335	COG0515	serine threonine protein kinase
KQ254_09335	COG2815	serine threonine protein kinase
KQ254_09405	COG3111	PFAM Bacterial OB fold (BOF) protein
KQ254_09430	COG3243	poly(R)-hydroxyalkanoic acid synthase
KQ254_09435	COG0786	glutamate:sodium symporter activity
KQ254_09445	COG2186	Transcriptional regulator
KQ254_09460	COG2826	transposase and inactivated derivatives, IS30 family
KQ254_09505	COG0477	Major facilitator Superfamily
KQ254_09530	COG2995	paraquat-inducible protein a
KQ254_09535	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KQ254_09535	COG3008	intermembrane lipid transfer
KQ254_09550	COG3118	belongs to the thioredoxin family
KQ254_09550	COG0492	ferredoxin-NADP+ reductase activity
KQ254_09555	COG1794	racemase activity, acting on amino acids and derivatives
KQ254_09585	COG3739	integral membrane protein
KQ254_09630	COG1301	dicarboxylic acid transport
KQ254_09640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KQ254_09645	COG2011	ABC-type metal ion transport system permease component
KQ254_09650	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KQ254_09655	COG1464	Belongs to the NlpA lipoprotein family
KQ254_09660	COG0151	Belongs to the GarS family
KQ254_09665	COG0138	bifunctional purine biosynthesis protein purh
KQ254_09670	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KQ254_09700	COG2308	Evidence 4 Homologs of previously reported genes of
KQ254_09710	COG1305	Transglutaminase-like
KQ254_09720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KQ254_09725	COG0305	Participates in initiation and elongation during chromosome replication
KQ254_09750	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KQ254_09760	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KQ254_09765	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KQ254_09790	COG1649	PFAM Uncharacterised BCR, COG1649
KQ254_09790	COG0726	polysaccharide deacetylase
KQ254_09795	COG1215	transferase activity, transferring glycosyl groups
KQ254_09800	COG3658	cytochrome
KQ254_09810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KQ254_09830	COG0583	DNA-binding transcription factor activity
KQ254_09850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KQ254_09855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KQ254_09870	COG1960	acyl-CoA dehydrogenase activity
KQ254_09875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KQ254_09880	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KQ254_09905	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KQ254_09910	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KQ254_09920	COG2205	protein histidine kinase activity
KQ254_09925	COG0745	RESPONSE REGULATOR receiver
KQ254_09930	COG0174	glutamine synthetase
KQ254_09950	COG0729	surface antigen
KQ254_09980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KQ254_09985	COG2814	Major facilitator Superfamily
KQ254_10000	COG0583	DNA-binding transcription factor activity
KQ254_10015	COG1187	pseudouridine synthase activity
KQ254_10035	COG0802	atpase or kinase
KQ254_10040	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KQ254_10050	COG1923	regulation of RNA biosynthetic process
KQ254_10055	COG0697	spore germination
KQ254_10080	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KQ254_10090	COG0519	Catalyzes the synthesis of GMP from XMP
KQ254_10090	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KQ254_10095	COG4302	ethanolamine ammonia-lyase activity
KQ254_10100	COG4303	Ethanolamine ammonia lyase large subunit
KQ254_10105	COG0531	amino acid
KQ254_10125	COG1454	alcohol dehydrogenase
KQ254_10130	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KQ254_10140	COG3708	Transcriptional regulator
KQ254_10140	COG2207	Transcriptional regulator
KQ254_10160	COG0308	aminopeptidase N
KQ254_10205	COG1605	Chorismate mutase
KQ254_10220	COG1309	transcriptional regulator
KQ254_10230	COG0668	transmembrane transport
KQ254_10260	COG4773	Receptor
KQ254_10280	COG0488	(ABC) transporter
KQ254_10285	COG0589	response to stress
KQ254_10310	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KQ254_10320	COG3135	benzoate transporter
KQ254_10325	COG1522	sequence-specific DNA binding
KQ254_10335	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KQ254_10340	COG0583	DNA-binding transcription factor activity
KQ254_10350	COG0183	Belongs to the thiolase family
KQ254_10360	COG2030	dehydratase
KQ254_10365	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KQ254_10380	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KQ254_10390	COG0824	Thioesterase
KQ254_10395	COG1454	alcohol dehydrogenase
KQ254_10405	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KQ254_10425	COG0069	glutamate synthase activity
KQ254_10445	COG2814	Major facilitator Superfamily
KQ254_10460	COG0511	ligase activity, forming carbon-carbon bonds
KQ254_10480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KQ254_10480	COG1116	anion transmembrane transporter activity
KQ254_10485	COG0745	RESPONSE REGULATOR receiver
KQ254_10495	COG2146	nitrite reductase [NAD(P)H] activity
KQ254_10495	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KQ254_10500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KQ254_10505	COG0243	molybdopterin cofactor binding
KQ254_10515	COG0243	molybdopterin cofactor binding
KQ254_10520	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KQ254_10535	COG0315	cyclic pyranopterin monophosphate synthase activity
KQ254_10535	COG0521	Mo-molybdopterin cofactor biosynthetic process
KQ254_10540	COG0303	'Molybdopterin
KQ254_10550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KQ254_10555	COG0697	spore germination
KQ254_10575	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KQ254_10580	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KQ254_10635	COG2826	transposase and inactivated derivatives, IS30 family
KQ254_10645	COG2204	response regulator
KQ254_10650	COG3852	Histidine kinase
KQ254_10670	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KQ254_10675	COG0575	Belongs to the CDS family
KQ254_10690	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KQ254_10710	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KQ254_10725	COG2137	regulation of response to DNA damage stimulus
KQ254_10735	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KQ254_10740	COG1011	Hydrolase
KQ254_10765	COG1522	sequence-specific DNA binding
KQ254_10775	COG1113	amino acid transport
KQ254_10795	COG0659	secondary active sulfate transmembrane transporter activity
KQ254_10800	COG2135	peptidase activity
KQ254_10815	COG3300	MHYT domain
KQ254_10815	COG5001	Diguanylate cyclase
KQ254_10835	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KQ254_10835	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KQ254_10835	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KQ254_10840	COG1105	Belongs to the carbohydrate kinase PfkB family
KQ254_10845	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KQ254_10845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KQ254_10875	COG0024	Methionine aminopeptidase
KQ254_10880	COG0583	DNA-binding transcription factor activity
KQ254_10890	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KQ254_10895	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KQ254_10900	COG0516	GMP reductase activity
KQ254_10900	COG0517	IMP dehydrogenase activity
KQ254_10925	COG0552	protein localization to endoplasmic reticulum
KQ254_10935	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
KQ254_10950	COG4890	Cyd operon protein YbgT
KQ254_10955	COG1294	oxidase, subunit
KQ254_10975	COG1585	Membrane protein implicated in regulation of membrane protease activity
KQ254_10985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KQ254_10990	COG4774	siderophore transport
KQ254_11005	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KQ254_11010	COG0569	domain protein
KQ254_11015	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KQ254_11045	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KQ254_11050	COG0542	response to heat
KQ254_11075	COG0446	pyridine nucleotide-disulphide oxidoreductase
KQ254_11075	COG1902	pentaerythritol trinitrate reductase activity
KQ254_11120	COG2323	membrane
KQ254_11125	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KQ254_11135	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KQ254_11140	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KQ254_11145	COG0183	Belongs to the thiolase family
KQ254_11150	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KQ254_11155	COG0596	Alpha beta hydrolase
KQ254_11160	COG2271	Major facilitator Superfamily
KQ254_11165	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KQ254_11170	COG3485	protocatechuate 3,4-dioxygenase
KQ254_11175	COG3485	protocatechuate 3,4-dioxygenase
KQ254_11180	COG0710	3-dehydroquinate dehydratase activity
KQ254_11185	COG3420	alginic acid biosynthetic process
KQ254_11195	COG4993	Dehydrogenase
KQ254_11205	COG2391	methyltransferase activity
KQ254_11220	COG1414	Transcriptional regulator
KQ254_11225	COG0583	DNA-binding transcription factor activity
KQ254_11230	COG1960	acyl-CoA dehydrogenase activity
KQ254_11255	COG2814	Major facilitator Superfamily
KQ254_11265	COG0154	amidase activity
KQ254_11285	COG4638	Rieske (2fe-2S)
KQ254_11295	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_11305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KQ254_11315	COG3733	amine oxidase
KQ254_11325	COG1012	belongs to the aldehyde dehydrogenase family
KQ254_11330	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KQ254_11335	COG0183	Belongs to the thiolase family
KQ254_11340	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KQ254_11345	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KQ254_11355	COG4829	muconolactone delta-isomerase
KQ254_11360	COG4948	Mandelate Racemase Muconate Lactonizing
KQ254_11365	COG0583	DNA-binding transcription factor activity
KQ254_11375	COG2186	Transcriptional regulator
KQ254_11395	COG1012	belongs to the aldehyde dehydrogenase family
KQ254_11410	COG0446	pyridine nucleotide-disulphide oxidoreductase
KQ254_11410	COG1902	pentaerythritol trinitrate reductase activity
KQ254_11425	COG0789	Transcriptional regulator
KQ254_11450	COG1309	transcriptional regulator
KQ254_11455	COG0583	DNA-binding transcription factor activity
KQ254_11460	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_11465	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_11470	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_11480	COG1960	acyl-CoA dehydrogenase activity
KQ254_11490	COG0318	PFAM AMP-dependent synthetase and ligase
KQ254_11565	COG2188	Transcriptional regulator
KQ254_11580	COG0583	DNA-binding transcription factor activity
KQ254_11620	COG1012	belongs to the aldehyde dehydrogenase family
KQ254_11625	COG0129	dihydroxy-acid dehydratase activity
KQ254_11635	COG0583	DNA-binding transcription factor activity
KQ254_11640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KQ254_11650	COG2084	Dehydrogenase
KQ254_11655	COG2207	Transcriptional regulator
KQ254_11670	COG1064	alcohol dehydrogenase
KQ254_11680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KQ254_11685	COG1120	ATPase activity
KQ254_11705	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KQ254_11755	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KQ254_11825	COG2826	transposase and inactivated derivatives, IS30 family
KQ254_11845	COG1073	alpha beta
KQ254_11855	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_11865	COG2207	Transcriptional regulator
KQ254_11875	COG2205	protein histidine kinase activity
KQ254_11880	COG0745	RESPONSE REGULATOR receiver
KQ254_11885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KQ254_11890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KQ254_11905	COG3539	Fimbrial protein
KQ254_11930	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KQ254_11940	COG0753	catalase activity
KQ254_11955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KQ254_12015	COG3433	isochorismatase activity
KQ254_12015	COG1535	isochorismatase
KQ254_12020	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_12025	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KQ254_12030	COG4149	molybdate abc transporter
KQ254_12035	COG0725	ABC transporter, periplasmic molybdate-binding protein
KQ254_12045	COG4638	Rieske (2fe-2S)
KQ254_12050	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KQ254_12055	COG0543	2 iron, 2 sulfur cluster binding
KQ254_12055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KQ254_12070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KQ254_12080	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_12095	COG2207	Transcriptional regulator
KQ254_12100	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_12105	COG2610	gluconate transmembrane transporter activity
KQ254_12115	COG0583	DNA-binding transcription factor activity
KQ254_12130	COG2031	fatty acid transporter
KQ254_12135	COG0183	Belongs to the thiolase family
KQ254_12140	COG0583	DNA-binding transcription factor activity
KQ254_12145	COG0583	DNA-binding transcription factor activity
KQ254_12160	COG1027	Aspartate ammonia-lyase
KQ254_12170	COG0477	Major facilitator Superfamily
KQ254_12190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KQ254_12195	COG4521	taurine ABC transporter
KQ254_12205	COG2081	HI0933 family
KQ254_12210	COG2188	Transcriptional regulator
KQ254_12220	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KQ254_12225	COG1733	regulation of RNA biosynthetic process
KQ254_12230	COG2207	Transcriptional regulator
KQ254_12230	COG3708	Transcriptional regulator
KQ254_12245	COG0730	response to heat
KQ254_12255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KQ254_12255	COG3453	Protein conserved in bacteria
KQ254_12265	COG3781	membrane
KQ254_12270	COG1063	alcohol dehydrogenase
KQ254_12280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KQ254_12285	COG0508	dehydrogenase complex catalyzes the overall conversion of
KQ254_12290	COG0022	dehydrogenase e1 component
KQ254_12295	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KQ254_12300	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KQ254_12315	COG2826	transposase and inactivated derivatives, IS30 family
KQ254_12325	COG3706	GGDEF domain
KQ254_12340	COG0133	tryptophan synthase activity
KQ254_12350	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KQ254_12385	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KQ254_12410	COG2226	methyltransferase
KQ254_12465	COG0842	Transport permease protein
KQ254_12470	COG0842	Transport permease protein
KQ254_12475	COG1131	(ABC) transporter
KQ254_12490	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KQ254_12495	COG4773	Receptor
KQ254_12515	COG0730	response to heat
KQ254_12520	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KQ254_12555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KQ254_12585	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KQ254_12595	COG4264	IucA IucC family
KQ254_12600	COG4264	IucA IucC family
KQ254_12620	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KQ254_12635	COG1960	acyl-CoA dehydrogenase activity
KQ254_12640	COG1960	acyl-CoA dehydrogenase activity
KQ254_12645	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KQ254_12650	COG2207	Transcriptional regulator
KQ254_12655	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KQ254_12660	COG0776	regulation of translation
KQ254_12685	COG0822	iron-sulfur transferase activity
KQ254_12690	COG0316	Belongs to the HesB IscA family
KQ254_12720	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KQ254_12740	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KQ254_12745	COG0702	epimerase
KQ254_12780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KQ254_12790	COG0339	signal peptide processing
KQ254_12810	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KQ254_12835	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KQ254_12840	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KQ254_12870	COG0776	regulation of translation
KQ254_12935	COG0084	hydrolase, TatD family'
KQ254_12955	COG1663	tetraacyldisaccharide 4'-kinase activity
KQ254_12960	COG1132	(ABC) transporter
KQ254_12970	COG0811	peptide transport
KQ254_12975	COG1475	DNA binding
KQ254_12980	COG1192	Involved in chromosome partitioning
KQ254_12990	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KQ254_13005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KQ254_13010	COG0191	fructose-bisphosphate aldolase activity
KQ254_13030	COG0424	maF-like protein
KQ254_13035	COG2850	peptidyl-arginine hydroxylation
KQ254_13055	COG0640	Transcriptional regulator
KQ254_13065	COG3619	membrane
KQ254_13070	COG3122	Protein conserved in bacteria
KQ254_13075	COG1132	(ABC) transporter
KQ254_13095	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KQ254_13100	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KQ254_13110	COG0506	proline dehydrogenase activity
KQ254_13110	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KQ254_13110	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KQ254_13115	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KQ254_13130	COG3698	Phosphodiester glycosidase
KQ254_13140	COG2353	YceI-like domain
KQ254_13150	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KQ254_13195	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KQ254_13195	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KQ254_13220	COG3539	Fimbrial protein
KQ254_13225	COG3121	Chaperone
KQ254_13250	COG0697	spore germination
KQ254_13260	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KQ254_13270	COG0583	DNA-binding transcription factor activity
KQ254_13315	COG1522	sequence-specific DNA binding
KQ254_13325	COG1126	abc transporter atp-binding protein
KQ254_13330	COG0765	amino acid transport
KQ254_13335	COG0765	amino acid transport
KQ254_13365	COG1464	Belongs to the NlpA lipoprotein family
KQ254_13375	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KQ254_13380	COG2011	ABC-type metal ion transport system permease component
KQ254_13385	COG0012	GTP binding
KQ254_13410	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KQ254_13450	COG0386	Belongs to the glutathione peroxidase family
KQ254_13460	COG0436	Aminotransferase
KQ254_13500	COG3634	alkyl hydroperoxide reductase activity
KQ254_13515	COG0583	DNA-binding transcription factor activity
KQ254_13520	COG0798	PFAM Bile acid sodium symporter
KQ254_13525	COG0640	Transcriptional regulator
KQ254_13540	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KQ254_13550	COG0583	DNA-binding transcription factor activity
KQ254_13560	COG1953	Uracil, thiamine, allantoin
KQ254_13570	COG2175	clavaminate synthase activity
KQ254_13575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KQ254_13580	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KQ254_13585	COG4521	taurine ABC transporter
KQ254_13595	COG0477	Major facilitator Superfamily
KQ254_13620	COG1271	oxidase subunit
KQ254_13625	COG1294	oxidase, subunit
KQ254_13635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KQ254_13655	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KQ254_13675	COG3052	prosthetic group binding
KQ254_13680	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
KQ254_13690	COG0583	DNA-binding transcription factor activity
KQ254_13700	COG2814	Major facilitator Superfamily
KQ254_13720	COG1346	cytolysis
KQ254_13730	COG0583	DNA-binding transcription factor activity
KQ254_13735	COG0625	glutathione transferase activity
KQ254_13740	COG0625	glutathione transferase activity
KQ254_13745	COG0583	DNA-binding transcription factor activity
KQ254_13750	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_13760	COG1045	serine acetyltransferase
KQ254_13765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KQ254_13770	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KQ254_13775	COG1280	lysine exporter protein (LysE YggA)
KQ254_13790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KQ254_13795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KQ254_13805	COG0765	amino acid transport
KQ254_13810	COG0765	amino acid transport
KQ254_13830	COG0784	Response regulator, receiver
KQ254_13830	COG2205	protein histidine kinase activity
KQ254_13850	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KQ254_13875	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_13925	COG0583	DNA-binding transcription factor activity
KQ254_13945	COG0318	PFAM AMP-dependent synthetase and ligase
KQ254_13950	COG1309	transcriptional regulator
KQ254_13955	COG1960	acyl-CoA dehydrogenase activity
KQ254_13960	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KQ254_13965	COG1024	Enoyl-CoA hydratase
KQ254_13970	COG4770	biotin carboxylase activity
KQ254_13980	COG0583	DNA-binding transcription factor activity
KQ254_13995	COG1960	acyl-CoA dehydrogenase activity
KQ254_14005	COG2814	Major facilitator Superfamily
KQ254_14015	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KQ254_14020	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KQ254_14025	COG2814	Major facilitator Superfamily
KQ254_14030	COG1960	acyl-CoA dehydrogenase activity
KQ254_14035	COG1024	Enoyl-CoA hydratase
KQ254_14040	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_14045	COG1250	3-hydroxyacyl-CoA dehydrogenase
KQ254_14050	COG0183	Belongs to the thiolase family
KQ254_14060	COG2814	Major facilitator Superfamily
KQ254_14070	COG1024	Enoyl-CoA hydratase
KQ254_14085	COG1960	acyl-CoA dehydrogenase activity
KQ254_14090	COG2814	Major facilitator Superfamily
KQ254_14095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KQ254_14100	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KQ254_14115	COG3842	ATPase activity
KQ254_14120	COG1840	ABC-type Fe3 transport system, periplasmic component
KQ254_14130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KQ254_14135	COG1414	Transcriptional regulator
KQ254_14145	COG0583	DNA-binding transcription factor activity
KQ254_14150	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KQ254_14155	COG1012	belongs to the aldehyde dehydrogenase family
KQ254_14165	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KQ254_14175	COG1012	belongs to the aldehyde dehydrogenase family
KQ254_14180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KQ254_14185	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KQ254_14190	COG2267	carboxylic ester hydrolase activity
KQ254_14210	COG3038	cytochrome b561
KQ254_14215	COG0753	catalase activity
KQ254_14250	COG2050	protein possibly involved in aromatic compounds catabolism
KQ254_14260	COG3327	negative regulation of DNA-templated transcription, initiation
KQ254_14265	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
KQ254_14270	COG0183	Belongs to the thiolase family
KQ254_14275	COG1250	3-hydroxyacyl-CoA dehydrogenase
KQ254_14280	COG1024	Enoyl-CoA hydratase
KQ254_14285	COG1024	Enoyl-CoA hydratase
KQ254_14290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KQ254_14295	COG2151	metal-sulfur cluster biosynthetic enzyme
KQ254_14300	COG3396	Phenylacetate-CoA oxygenase
KQ254_14305	COG3460	Phenylacetate-CoA oxygenase
KQ254_14310	COG3396	Phenylacetate-CoA oxygenase
KQ254_14315	COG2030	dehydratase
KQ254_14315	COG1012	belongs to the aldehyde dehydrogenase family
KQ254_14320	COG1760	l-serine dehydratase
KQ254_14325	COG0531	amino acid
KQ254_14330	COG1012	belongs to the aldehyde dehydrogenase family
KQ254_14355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KQ254_14375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KQ254_14385	COG0789	Transcriptional regulator
KQ254_14395	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KQ254_14410	COG2807	transmembrane transport
KQ254_14415	COG0590	tRNA wobble adenosine to inosine editing
KQ254_14540	COG1116	anion transmembrane transporter activity
KQ254_14555	COG0864	Transcriptional regulator
KQ254_14565	COG1733	regulation of RNA biosynthetic process
KQ254_14570	COG2249	NAD(P)H dehydrogenase (quinone) activity
KQ254_14575	COG0439	Biotin carboxylase
KQ254_14590	COG1063	alcohol dehydrogenase
KQ254_14600	COG1309	transcriptional regulator
KQ254_14615	COG2826	transposase and inactivated derivatives, IS30 family
KQ254_14625	COG4770	biotin carboxylase activity
KQ254_14645	COG1914	H( )-stimulated, divalent metal cation uptake system
KQ254_14650	COG0583	DNA-binding transcription factor activity
KQ254_14690	COG1250	3-hydroxyacyl-CoA dehydrogenase
KQ254_14710	COG2814	Major facilitator Superfamily
KQ254_14720	COG1560	Kdo2-lipid A biosynthetic process
KQ254_14730	COG5006	permease, DMT superfamily
KQ254_14735	COG1522	sequence-specific DNA binding
KQ254_14750	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KQ254_14760	COG4122	O-methyltransferase activity
KQ254_14790	COG1538	Outer membrane efflux protein
KQ254_14795	COG1137	ATPase activity
KQ254_14800	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KQ254_14810	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KQ254_14815	COG0517	IMP dehydrogenase activity
KQ254_14815	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KQ254_14855	COG2814	Major facilitator Superfamily
KQ254_14890	COG1278	Cold shock
KQ254_14895	COG1280	lysine exporter protein (LysE YggA)
KQ254_14925	COG1570	exodeoxyribonuclease VII activity
KQ254_14975	COG0583	DNA-binding transcription factor activity
KQ254_14980	COG4638	Rieske (2fe-2S)
KQ254_14985	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KQ254_14990	COG0543	2 iron, 2 sulfur cluster binding
KQ254_14990	COG0633	Ferredoxin
KQ254_14995	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_15000	COG3135	benzoate transporter
KQ254_15005	COG2814	Major facilitator Superfamily
KQ254_15020	COG1643	Atp-dependent helicase
KQ254_15025	COG0450	alkyl hydroperoxide reductase
KQ254_15035	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KQ254_15045	COG3634	alkyl hydroperoxide reductase activity
KQ254_15065	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KQ254_15070	COG0625	glutathione transferase activity
KQ254_15085	COG2885	chlorophyll binding
KQ254_15120	COG0542	response to heat
KQ254_15135	COG1765	OsmC-like protein
KQ254_15150	COG0667	Aldo Keto reductase
KQ254_15165	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KQ254_15180	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KQ254_15190	COG0527	aspartate kinase activity
KQ254_15200	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KQ254_15210	COG3038	cytochrome b561
KQ254_15215	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KQ254_15220	COG2252	PERMEase
KQ254_15230	COG2072	flavoprotein involved in K transport
KQ254_15245	COG1741	Belongs to the pirin family
KQ254_15250	COG1309	transcriptional regulator
KQ254_15260	COG0300	oxidoreductase activity
KQ254_15265	COG2072	flavoprotein involved in K transport
KQ254_15270	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KQ254_15315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KQ254_15330	COG2814	Major facilitator Superfamily
KQ254_15335	COG1024	Enoyl-CoA hydratase
KQ254_15340	COG1012	belongs to the aldehyde dehydrogenase family
KQ254_15350	COG1960	acyl-CoA dehydrogenase activity
KQ254_15370	COG1113	amino acid transport
KQ254_15420	COG0446	pyridine nucleotide-disulphide oxidoreductase
KQ254_15420	COG1902	pentaerythritol trinitrate reductase activity
KQ254_15430	COG2203	Gaf domain
KQ254_15430	COG4251	negative regulation of phosphorylation
KQ254_15430	COG5001	Diguanylate cyclase
KQ254_15430	COG3706	GGDEF domain
KQ254_15440	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KQ254_15460	COG4172	Belongs to the ABC transporter superfamily
KQ254_15465	COG4239	(ABC) transporter, permease
KQ254_15470	COG4174	ABC transporter (Permease)
KQ254_15480	COG1388	LysM domain
KQ254_15480	COG0741	lytic transglycosylase activity
KQ254_15480	COG1388	LysM domain
KQ254_15480	COG0741	lytic transglycosylase activity
KQ254_15485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KQ254_15530	COG1279	arginine transmembrane transporter activity
KQ254_15550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KQ254_15555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KQ254_15560	COG0006	proline dipeptidase activity
KQ254_15640	COG0741	lytic transglycosylase activity
KQ254_15640	COG0739	heme binding
KQ254_15640	COG1196	nuclear chromosome segregation
KQ254_15710	COG0305	Participates in initiation and elongation during chromosome replication
KQ254_15725	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KQ254_15775	COG2194	sulfuric ester hydrolase activity
KQ254_15835	COG2826	transposase and inactivated derivatives, IS30 family
KQ254_16115	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KQ254_16145	COG3384	dioxygenase
KQ254_16155	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KQ254_16160	COG2878	Part of a membrane complex involved in electron transport
KQ254_16165	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KQ254_16190	COG0768	penicillin binding
KQ254_16195	COG0742	ribosomal rna small subunit methyltransferase
KQ254_16210	COG0830	nickel cation binding
KQ254_16255	COG1253	flavin adenine dinucleotide binding
KQ254_16260	COG2851	Citrate transporter
KQ254_16310	COG1773	rubredoxin
KQ254_16315	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KQ254_16325	COG0583	DNA-binding transcription factor activity
KQ254_16355	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KQ254_16360	COG4181	ATPase activity
KQ254_16405	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KQ254_16425	COG0306	phosphate transporter
KQ254_16435	COG3958	Transketolase
KQ254_16440	COG3959	Transketolase, thiamine diphosphate binding domain
KQ254_16445	COG2271	Major facilitator Superfamily
KQ254_16450	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_16455	COG0583	DNA-binding transcription factor activity
KQ254_16475	COG2223	nitrite transmembrane transporter activity
KQ254_16480	COG2207	Transcriptional regulator
KQ254_16485	COG2066	Belongs to the glutaminase family
KQ254_16490	COG0242	peptide deformylase activity
KQ254_16495	COG0477	Major facilitator Superfamily
KQ254_16505	COG0028	Belongs to the TPP enzyme family
KQ254_16520	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_16525	COG2267	carboxylic ester hydrolase activity
KQ254_16535	COG2271	Major facilitator Superfamily
KQ254_16540	COG0446	pyridine nucleotide-disulphide oxidoreductase
KQ254_16550	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_16570	COG1414	Transcriptional regulator
KQ254_16585	COG1024	Enoyl-CoA hydratase
KQ254_16595	COG1215	transferase activity, transferring glycosyl groups
KQ254_16600	COG0726	polysaccharide deacetylase
KQ254_16600	COG1649	PFAM Uncharacterised BCR, COG1649
KQ254_16610	COG4681	YaeQ
KQ254_16620	COG0523	cobalamin synthesis protein
KQ254_16630	COG1607	acyl-coa hydrolase
KQ254_16640	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KQ254_16645	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KQ254_16650	COG1309	transcriptional regulator
KQ254_16675	COG2040	homocysteine
KQ254_16680	COG0531	amino acid
KQ254_16735	COG1595	DNA-templated transcription, initiation
KQ254_16745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KQ254_16750	COG0477	Major facilitator Superfamily
KQ254_16775	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KQ254_16785	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KQ254_16805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KQ254_16890	COG0592	DNA-directed DNA polymerase activity
KQ254_16930	COG2026	Addiction module toxin, RelE StbE family
KQ254_17125	COG1484	DNA-dependent DNA replication
KQ254_17220	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KQ254_17290	COG0405	Gamma-glutamyltransferase
KQ254_17295	COG2814	Major facilitator Superfamily
KQ254_17305	COG2050	protein possibly involved in aromatic compounds catabolism
KQ254_17320	COG1090	epimerase
KQ254_17340	COG0420	3'-5' exonuclease activity
KQ254_17365	COG2826	transposase and inactivated derivatives, IS30 family
KQ254_17375	COG0735	belongs to the Fur family
KQ254_17380	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KQ254_17400	COG0121	glutamine amidotransferase
KQ254_17415	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KQ254_17425	COG0210	DNA helicase
KQ254_17430	COG2885	chlorophyll binding
KQ254_17435	COG0204	Acyl-transferase
KQ254_17450	COG2894	cell division
KQ254_17465	COG1280	lysine exporter protein (LysE YggA)
KQ254_17470	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KQ254_17470	COG1674	ftsk spoiiie
KQ254_17475	COG0492	ferredoxin-NADP+ reductase activity
KQ254_17480	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KQ254_17490	COG0456	acetyltransferase
KQ254_17535	COG1981	membrane
KQ254_17550	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KQ254_17550	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KQ254_17570	COG1012	belongs to the aldehyde dehydrogenase family
KQ254_17580	COG0657	acetylesterase activity
KQ254_17590	COG0473	3-isopropylmalate dehydrogenase activity
KQ254_17595	COG0583	DNA-binding transcription factor activity
KQ254_17615	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KQ254_17625	COG0582	viral genome integration into host DNA
KQ254_17940	COG0564	pseudouridine synthase activity
KQ254_17950	COG0358	DNA primase activity
KQ254_17970	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KQ254_18000	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KQ254_18030	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KQ254_18040	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KQ254_18040	COG0352	thiamine-phosphate diphosphorylase activity
KQ254_18040	COG0351	phosphomethylpyrimidine kinase
KQ254_18045	COG1652	LysM domain
KQ254_18070	COG1399	metal-binding, possibly nucleic acid-binding protein
KQ254_18075	COG3101	peptidyl-lysine hydroxylation
KQ254_18080	COG0009	L-threonylcarbamoyladenylate synthase
KQ254_18085	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KQ254_18090	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KQ254_18105	COG4106	trans-aconitate 2-methyltransferase activity
KQ254_18120	COG0596	Alpha beta hydrolase
KQ254_18120	COG2226	methyltransferase
KQ254_18120	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KQ254_18125	COG1877	trehalose-phosphatase activity
KQ254_18130	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
KQ254_18135	COG2223	nitrite transmembrane transporter activity
KQ254_18155	COG1196	nuclear chromosome segregation
KQ254_18165	COG0730	response to heat
KQ254_18180	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KQ254_18190	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KQ254_18240	COG0489	protein tyrosine kinase activity
KQ254_18250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KQ254_18250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KQ254_18280	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KQ254_18285	COG2081	HI0933 family
KQ254_18295	COG0668	transmembrane transport
KQ254_18315	COG0583	DNA-binding transcription factor activity
KQ254_18335	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KQ254_18340	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KQ254_18370	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KQ254_18395	COG3706	GGDEF domain
KQ254_18410	COG0745	RESPONSE REGULATOR receiver
KQ254_18430	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KQ254_18445	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KQ254_18460	COG0583	DNA-binding transcription factor activity
KQ254_18470	COG0583	DNA-binding transcription factor activity
KQ254_18485	COG0583	DNA-binding transcription factor activity
KQ254_18490	COG1053	succinate dehydrogenase
KQ254_18505	COG1309	transcriptional regulator
KQ254_18510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KQ254_18515	COG2814	Major facilitator Superfamily
KQ254_18520	COG1960	acyl-CoA dehydrogenase activity
KQ254_18525	COG0583	DNA-binding transcription factor activity
KQ254_18560	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KQ254_18565	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KQ254_18570	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KQ254_18585	COG3667	copper resistance
KQ254_18590	COG2132	Multicopper oxidase
KQ254_18600	COG0561	phosphatase activity
KQ254_18605	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KQ254_18615	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
KQ254_18630	COG1214	PFAM Peptidase M22, glycoprotease
KQ254_18650	COG3328	transposase activity
KQ254_18665	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KQ254_18675	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KQ254_18680	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KQ254_18685	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KQ254_18745	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KQ254_18755	COG1846	Transcriptional regulator
KQ254_18760	COG1764	response to oxidative stress
KQ254_18800	COG0037	tRNA processing
KQ254_18810	COG0248	Ppx GppA phosphatase
KQ254_18840	COG0072	phenylalanine-tRNA ligase activity
KQ254_18880	COG1238	metal cluster binding
KQ254_18885	COG0625	glutathione transferase activity
KQ254_18900	COG0318	PFAM AMP-dependent synthetase and ligase
KQ254_18905	COG3028	Belongs to the UPF0307 family
KQ254_18910	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KQ254_18930	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KQ254_18935	COG0617	tRNA 3'-terminal CCA addition
KQ254_18940	COG1555	photosystem II stabilization
KQ254_18945	COG3956	TIGRFAM MazG family protein
KQ254_18955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KQ254_18975	COG2205	protein histidine kinase activity
KQ254_18975	COG5002	protein histidine kinase activity
KQ254_18975	COG0784	Response regulator, receiver
KQ254_18980	COG1024	Enoyl-CoA hydratase
KQ254_18985	COG2084	Dehydrogenase
KQ254_18990	COG3622	Belongs to the hyi family
KQ254_19020	COG0697	spore germination
KQ254_19030	COG2814	Major facilitator Superfamily
KQ254_19035	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KQ254_19045	COG0583	DNA-binding transcription factor activity
KQ254_19055	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KQ254_19065	COG0084	hydrolase, TatD family'
KQ254_19080	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KQ254_19100	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KQ254_19105	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KQ254_19135	COG2184	nucleotidyltransferase activity
KQ254_19155	COG1785	Belongs to the alkaline phosphatase family
KQ254_19215	COG2948	multi-organism process
KQ254_19230	COG0582	viral genome integration into host DNA
KQ254_19260	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KQ254_19320	COG2826	transposase and inactivated derivatives, IS30 family
KQ254_19330	COG2826	transposase and inactivated derivatives, IS30 family
KQ254_19400	COG0582	viral genome integration into host DNA
KQ254_19570	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system