locus-tag	class	description
KQ253_00170	COG2026	Addiction module toxin, RelE StbE family
KQ253_00210	COG0592	DNA-directed DNA polymerase activity
KQ253_00315	COG0582	viral genome integration into host DNA
KQ253_00365	COG2826	transposase and inactivated derivatives, IS30 family
KQ253_00375	COG0629	single-stranded DNA binding
KQ253_00390	COG2826	transposase and inactivated derivatives, IS30 family
KQ253_00415	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KQ253_00445	COG0477	Major facilitator Superfamily
KQ253_00450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KQ253_00460	COG1595	DNA-templated transcription, initiation
KQ253_00515	COG0531	amino acid
KQ253_00545	COG1309	transcriptional regulator
KQ253_00565	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KQ253_00575	COG1607	acyl-coa hydrolase
KQ253_00585	COG0523	cobalamin synthesis protein
KQ253_00595	COG4681	YaeQ
KQ253_00605	COG1649	PFAM Uncharacterised BCR, COG1649
KQ253_00605	COG0726	polysaccharide deacetylase
KQ253_00610	COG1215	transferase activity, transferring glycosyl groups
KQ253_00620	COG1024	Enoyl-CoA hydratase
KQ253_00635	COG1414	Transcriptional regulator
KQ253_00655	COG1028	Short-chain dehydrogenase reductase Sdr
KQ253_00670	COG2271	Major facilitator Superfamily
KQ253_00680	COG2267	carboxylic ester hydrolase activity
KQ253_00685	COG1028	Short-chain dehydrogenase reductase Sdr
KQ253_00700	COG0028	Belongs to the TPP enzyme family
KQ253_00710	COG0477	Major facilitator Superfamily
KQ253_00715	COG0242	peptide deformylase activity
KQ253_00720	COG2066	Belongs to the glutaminase family
KQ253_00725	COG2207	Transcriptional regulator
KQ253_00730	COG2223	nitrite transmembrane transporter activity
KQ253_00745	COG0583	DNA-binding transcription factor activity
KQ253_00750	COG1028	Short-chain dehydrogenase reductase Sdr
KQ253_00755	COG2271	Major facilitator Superfamily
KQ253_00760	COG3959	Transketolase, thiamine diphosphate binding domain
KQ253_00765	COG3958	Transketolase
KQ253_00775	COG0306	phosphate transporter
KQ253_00795	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KQ253_00850	COG4181	ATPase activity
KQ253_00885	COG0583	DNA-binding transcription factor activity
KQ253_00895	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KQ253_00900	COG1773	rubredoxin
KQ253_00950	COG2851	Citrate transporter
KQ253_00955	COG1253	flavin adenine dinucleotide binding
KQ253_01000	COG0804	urea catabolic process
KQ253_01010	COG0830	nickel cation binding
KQ253_01025	COG0742	ribosomal rna small subunit methyltransferase
KQ253_01030	COG0768	penicillin binding
KQ253_01055	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KQ253_01060	COG2878	Part of a membrane complex involved in electron transport
KQ253_01065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KQ253_01075	COG3384	dioxygenase
KQ253_01100	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KQ253_01155	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KQ253_01170	COG0305	Participates in initiation and elongation during chromosome replication
KQ253_01385	COG0006	proline dipeptidase activity
KQ253_01390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KQ253_01395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KQ253_01415	COG1279	arginine transmembrane transporter activity
KQ253_01420	COG0583	DNA-binding transcription factor activity
KQ253_01460	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KQ253_01465	COG0741	lytic transglycosylase activity
KQ253_01465	COG1388	LysM domain
KQ253_01465	COG0741	lytic transglycosylase activity
KQ253_01465	COG1388	LysM domain
KQ253_01475	COG4174	ABC transporter (Permease)
KQ253_01480	COG4239	(ABC) transporter, permease
KQ253_01485	COG4172	Belongs to the ABC transporter superfamily
KQ253_01505	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KQ253_01515	COG5001	Diguanylate cyclase
KQ253_01515	COG2203	Gaf domain
KQ253_01515	COG4251	negative regulation of phosphorylation
KQ253_01515	COG3706	GGDEF domain
KQ253_01525	COG0446	pyridine nucleotide-disulphide oxidoreductase
KQ253_01525	COG1902	pentaerythritol trinitrate reductase activity
KQ253_01620	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KQ253_01625	COG2072	flavoprotein involved in K transport
KQ253_01630	COG0300	oxidoreductase activity
KQ253_01640	COG1309	transcriptional regulator
KQ253_01645	COG1741	Belongs to the pirin family
KQ253_01660	COG2072	flavoprotein involved in K transport
KQ253_01670	COG2252	PERMEase
KQ253_01675	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KQ253_01680	COG3038	cytochrome b561
KQ253_01690	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KQ253_01700	COG0527	aspartate kinase activity
KQ253_01710	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KQ253_01720	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KQ253_01735	COG0667	Aldo Keto reductase
KQ253_01750	COG1765	OsmC-like protein
KQ253_01765	COG0542	response to heat
KQ253_01800	COG2885	chlorophyll binding
KQ253_01810	COG0625	glutathione transferase activity
KQ253_01815	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KQ253_01840	COG3634	alkyl hydroperoxide reductase activity
KQ253_01850	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KQ253_01860	COG0450	alkyl hydroperoxide reductase
KQ253_01865	COG1643	Atp-dependent helicase
KQ253_01880	COG2814	Major facilitator Superfamily
KQ253_01885	COG3135	benzoate transporter
KQ253_01890	COG1028	Short-chain dehydrogenase reductase Sdr
KQ253_01895	COG0543	2 iron, 2 sulfur cluster binding
KQ253_01895	COG0633	Ferredoxin
KQ253_01900	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KQ253_01905	COG4638	Rieske (2fe-2S)
KQ253_01910	COG0583	DNA-binding transcription factor activity
KQ253_01920	COG2871	sodium ion transport
KQ253_02000	COG1570	exodeoxyribonuclease VII activity
KQ253_02035	COG1280	lysine exporter protein (LysE YggA)
KQ253_02040	COG1278	Cold shock
KQ253_02075	COG2814	Major facilitator Superfamily
KQ253_02120	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KQ253_02130	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KQ253_02135	COG1137	ATPase activity
KQ253_02140	COG1538	Outer membrane efflux protein
KQ253_02170	COG4122	O-methyltransferase activity
KQ253_02180	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KQ253_02195	COG1522	sequence-specific DNA binding
KQ253_02200	COG5006	permease, DMT superfamily
KQ253_02210	COG1560	Kdo2-lipid A biosynthetic process
KQ253_02245	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KQ253_02270	COG1250	3-hydroxyacyl-CoA dehydrogenase
KQ253_02330	COG0583	DNA-binding transcription factor activity
KQ253_02335	COG1914	H( )-stimulated, divalent metal cation uptake system
KQ253_02355	COG4770	biotin carboxylase activity
KQ253_02360	COG0038	chloride channel
KQ253_02385	COG1063	alcohol dehydrogenase
KQ253_02400	COG0439	Biotin carboxylase
KQ253_02405	COG2249	NAD(P)H dehydrogenase (quinone) activity
KQ253_02410	COG1733	regulation of RNA biosynthetic process
KQ253_02420	COG0864	Transcriptional regulator
KQ253_02430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KQ253_02435	COG1116	anion transmembrane transporter activity
KQ253_02550	COG0590	tRNA wobble adenosine to inosine editing
KQ253_02555	COG2807	transmembrane transport
KQ253_02570	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KQ253_02580	COG0789	Transcriptional regulator
KQ253_02590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KQ253_02610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KQ253_02640	COG0531	amino acid
KQ253_02645	COG1760	l-serine dehydratase
KQ253_02650	COG1012	belongs to the aldehyde dehydrogenase family
KQ253_02650	COG2030	dehydratase
KQ253_02655	COG3396	Phenylacetate-CoA oxygenase
KQ253_02660	COG3460	Phenylacetate-CoA oxygenase
KQ253_02665	COG3396	Phenylacetate-CoA oxygenase
KQ253_02670	COG2151	metal-sulfur cluster biosynthetic enzyme
KQ253_02675	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KQ253_02680	COG1024	Enoyl-CoA hydratase
KQ253_02685	COG1024	Enoyl-CoA hydratase
KQ253_02690	COG1250	3-hydroxyacyl-CoA dehydrogenase
KQ253_02695	COG0183	Belongs to the thiolase family
KQ253_02700	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
KQ253_02705	COG3327	negative regulation of DNA-templated transcription, initiation
KQ253_02715	COG2050	protein possibly involved in aromatic compounds catabolism
KQ253_02740	COG0753	catalase activity
KQ253_02745	COG3038	cytochrome b561
KQ253_02765	COG2267	carboxylic ester hydrolase activity
KQ253_02770	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KQ253_02775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KQ253_02780	COG1012	belongs to the aldehyde dehydrogenase family
KQ253_02790	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KQ253_02800	COG1012	belongs to the aldehyde dehydrogenase family
KQ253_02805	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KQ253_02810	COG0583	DNA-binding transcription factor activity
KQ253_02820	COG1414	Transcriptional regulator
KQ253_02825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KQ253_02835	COG1840	ABC-type Fe3 transport system, periplasmic component
KQ253_02840	COG3842	ATPase activity
KQ253_02855	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KQ253_02860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KQ253_02865	COG2814	Major facilitator Superfamily
KQ253_02870	COG1960	acyl-CoA dehydrogenase activity
KQ253_02885	COG1024	Enoyl-CoA hydratase
KQ253_02900	COG2192	nodulation
KQ253_02910	COG1280	lysine exporter protein (LysE YggA)
KQ253_02925	COG0183	Belongs to the thiolase family
KQ253_02930	COG1250	3-hydroxyacyl-CoA dehydrogenase
KQ253_02935	COG1028	Short-chain dehydrogenase reductase Sdr
KQ253_02940	COG1024	Enoyl-CoA hydratase
KQ253_02945	COG1960	acyl-CoA dehydrogenase activity
KQ253_02950	COG2814	Major facilitator Superfamily
KQ253_02955	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KQ253_02960	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KQ253_02970	COG2814	Major facilitator Superfamily
KQ253_02980	COG1960	acyl-CoA dehydrogenase activity
KQ253_02995	COG0583	DNA-binding transcription factor activity
KQ253_03005	COG4770	biotin carboxylase activity
KQ253_03010	COG1024	Enoyl-CoA hydratase
KQ253_03015	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KQ253_03020	COG1960	acyl-CoA dehydrogenase activity
KQ253_03025	COG1309	transcriptional regulator
KQ253_03030	COG0318	PFAM AMP-dependent synthetase and ligase
KQ253_03050	COG0583	DNA-binding transcription factor activity
KQ253_03100	COG1028	Short-chain dehydrogenase reductase Sdr
KQ253_03120	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KQ253_03140	COG0784	Response regulator, receiver
KQ253_03140	COG2205	protein histidine kinase activity
KQ253_03160	COG0765	amino acid transport
KQ253_03165	COG0765	amino acid transport
KQ253_03170	COG1126	abc transporter atp-binding protein
KQ253_03175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KQ253_03180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KQ253_03195	COG1280	lysine exporter protein (LysE YggA)
KQ253_03205	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KQ253_03210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KQ253_03215	COG1045	serine acetyltransferase
KQ253_03230	COG0583	DNA-binding transcription factor activity
KQ253_03235	COG0625	glutathione transferase activity
KQ253_03245	COG0583	DNA-binding transcription factor activity
KQ253_03255	COG1346	cytolysis
KQ253_03275	COG2814	Major facilitator Superfamily
KQ253_03285	COG0583	DNA-binding transcription factor activity
KQ253_03295	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
KQ253_03300	COG3052	prosthetic group binding
KQ253_03320	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KQ253_03340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KQ253_03350	COG1294	oxidase, subunit
KQ253_03355	COG1271	oxidase subunit
KQ253_03375	COG0477	Major facilitator Superfamily
KQ253_03390	COG4521	taurine ABC transporter
KQ253_03400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KQ253_03405	COG2175	clavaminate synthase activity
KQ253_03415	COG1953	Uracil, thiamine, allantoin
KQ253_03425	COG0583	DNA-binding transcription factor activity
KQ253_03435	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KQ253_03450	COG0640	Transcriptional regulator
KQ253_03455	COG0798	PFAM Bile acid sodium symporter
KQ253_03460	COG0583	DNA-binding transcription factor activity
KQ253_03475	COG3634	alkyl hydroperoxide reductase activity
KQ253_03510	COG1301	dicarboxylic acid transport
KQ253_03515	COG0436	Aminotransferase
KQ253_03525	COG0386	Belongs to the glutathione peroxidase family
KQ253_03540	COG0436	Aminotransferase
KQ253_03565	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KQ253_03590	COG0012	GTP binding
KQ253_03595	COG2011	ABC-type metal ion transport system permease component
KQ253_03600	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KQ253_03610	COG1464	Belongs to the NlpA lipoprotein family
KQ253_03640	COG0765	amino acid transport
KQ253_03645	COG0765	amino acid transport
KQ253_03650	COG1126	abc transporter atp-binding protein
KQ253_03660	COG1522	sequence-specific DNA binding
KQ253_03675	COG1309	transcriptional regulator
KQ253_03695	COG0583	DNA-binding transcription factor activity
KQ253_03705	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KQ253_03715	COG0697	spore germination
KQ253_03740	COG3121	Chaperone
KQ253_03745	COG3539	Fimbrial protein
KQ253_03770	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KQ253_03770	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KQ253_03815	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KQ253_03825	COG2353	YceI-like domain
KQ253_03835	COG3698	Phosphodiester glycosidase
KQ253_03850	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KQ253_03855	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KQ253_03855	COG0506	proline dehydrogenase activity
KQ253_03855	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KQ253_03865	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KQ253_03870	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KQ253_03890	COG1132	(ABC) transporter
KQ253_03895	COG3122	Protein conserved in bacteria
KQ253_03900	COG3619	membrane
KQ253_03910	COG0640	Transcriptional regulator
KQ253_03920	COG2850	peptidyl-arginine hydroxylation
KQ253_03925	COG0424	maF-like protein
KQ253_03945	COG0191	fructose-bisphosphate aldolase activity
KQ253_03950	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KQ253_03965	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KQ253_03975	COG1192	Involved in chromosome partitioning
KQ253_03980	COG1475	DNA binding
KQ253_03985	COG0811	peptide transport
KQ253_03995	COG1132	(ABC) transporter
KQ253_04000	COG1663	tetraacyldisaccharide 4'-kinase activity
KQ253_04020	COG0084	hydrolase, TatD family'
KQ253_04085	COG0776	regulation of translation
KQ253_04110	COG2826	transposase and inactivated derivatives, IS30 family
KQ253_04120	COG2826	transposase and inactivated derivatives, IS30 family
KQ253_04135	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KQ253_04190	COG0305	Participates in initiation and elongation during chromosome replication
KQ253_04310	COG3646	Phage regulatory protein
KQ253_04340	COG0741	lytic transglycosylase activity
KQ253_04340	COG1196	nuclear chromosome segregation
KQ253_04340	COG0739	heme binding
KQ253_04400	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KQ253_04470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KQ253_04505	COG0702	epimerase
KQ253_04510	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KQ253_04530	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KQ253_04560	COG0316	Belongs to the HesB IscA family
KQ253_04565	COG0822	iron-sulfur transferase activity
KQ253_04590	COG0776	regulation of translation
KQ253_04595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KQ253_04600	COG2207	Transcriptional regulator
KQ253_04605	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KQ253_04610	COG1960	acyl-CoA dehydrogenase activity
KQ253_04615	COG1960	acyl-CoA dehydrogenase activity
KQ253_04630	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KQ253_04645	COG2814	Major facilitator Superfamily
KQ253_04650	COG4264	IucA IucC family
KQ253_04655	COG4264	IucA IucC family
KQ253_04665	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KQ253_04695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KQ253_04710	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KQ253_04715	COG0406	alpha-ribazole phosphatase activity
KQ253_04730	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KQ253_04735	COG0730	response to heat
KQ253_04755	COG4773	Receptor
KQ253_04760	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KQ253_04775	COG1131	(ABC) transporter
KQ253_04790	COG0842	Transport permease protein
KQ253_04880	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KQ253_04915	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KQ253_04925	COG0133	tryptophan synthase activity
KQ253_04940	COG3706	GGDEF domain
KQ253_04955	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KQ253_04960	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KQ253_04965	COG0022	dehydrogenase e1 component
KQ253_04970	COG0508	dehydrogenase complex catalyzes the overall conversion of
KQ253_04975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KQ253_04985	COG1063	alcohol dehydrogenase
KQ253_04990	COG3781	membrane
KQ253_05000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KQ253_05000	COG3453	Protein conserved in bacteria
KQ253_05010	COG0730	response to heat
KQ253_05025	COG2207	Transcriptional regulator
KQ253_05025	COG3708	Transcriptional regulator
KQ253_05030	COG1733	regulation of RNA biosynthetic process
KQ253_05035	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KQ253_05045	COG2188	Transcriptional regulator
KQ253_05060	COG4521	taurine ABC transporter
KQ253_05065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KQ253_05085	COG0477	Major facilitator Superfamily
KQ253_05095	COG1027	Aspartate ammonia-lyase
KQ253_05110	COG0583	DNA-binding transcription factor activity
KQ253_05115	COG0583	DNA-binding transcription factor activity
KQ253_05120	COG0183	Belongs to the thiolase family
KQ253_05125	COG2031	fatty acid transporter
KQ253_05140	COG0583	DNA-binding transcription factor activity
KQ253_05160	COG1309	transcriptional regulator
KQ253_05170	COG2610	gluconate transmembrane transporter activity
KQ253_05175	COG1028	Short-chain dehydrogenase reductase Sdr
KQ253_05180	COG2207	Transcriptional regulator
KQ253_05195	COG1028	Short-chain dehydrogenase reductase Sdr
KQ253_05205	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KQ253_05220	COG0543	2 iron, 2 sulfur cluster binding
KQ253_05220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KQ253_05225	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KQ253_05230	COG4638	Rieske (2fe-2S)
KQ253_05240	COG0725	ABC transporter, periplasmic molybdate-binding protein
KQ253_05245	COG4149	molybdate abc transporter
KQ253_05250	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KQ253_05255	COG1028	Short-chain dehydrogenase reductase Sdr
KQ253_05260	COG1535	isochorismatase
KQ253_05260	COG3433	isochorismatase activity
KQ253_05325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KQ253_05350	COG0753	catalase activity
KQ253_05360	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KQ253_05385	COG3539	Fimbrial protein
KQ253_05580	COG0656	L-ascorbic acid biosynthetic process
KQ253_05585	COG0494	nUDIX hydrolase
KQ253_05600	COG3328	transposase activity
KQ253_05615	COG1609	Transcriptional regulator
KQ253_05625	COG0028	Belongs to the TPP enzyme family
KQ253_05635	COG4580	involved in the transport of maltose and maltodextrins
KQ253_05650	COG0483	inositol monophosphate 1-phosphatase activity
KQ253_05675	COG0028	Belongs to the TPP enzyme family
KQ253_05680	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KQ253_05685	COG1346	cytolysis
KQ253_05690	COG1609	Transcriptional regulator
KQ253_05700	COG0697	spore germination
KQ253_05710	COG2223	nitrite transmembrane transporter activity
KQ253_05725	COG4580	involved in the transport of maltose and maltodextrins
KQ253_05730	COG1028	Short-chain dehydrogenase reductase Sdr
KQ253_05735	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
KQ253_05740	COG2267	carboxylic ester hydrolase activity
KQ253_05755	COG3938	Belongs to the proline racemase family
KQ253_05760	COG1012	belongs to the aldehyde dehydrogenase family
KQ253_05775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KQ253_05795	COG2072	flavoprotein involved in K transport
KQ253_05810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KQ253_05815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KQ253_05820	COG0745	RESPONSE REGULATOR receiver
KQ253_05825	COG2205	protein histidine kinase activity
KQ253_05835	COG2207	Transcriptional regulator
KQ253_05845	COG1028	Short-chain dehydrogenase reductase Sdr
KQ253_05855	COG1073	alpha beta
KQ253_05915	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KQ253_05960	COG2826	transposase and inactivated derivatives, IS30 family
KQ253_05980	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KQ253_06000	COG1120	ATPase activity
KQ253_06005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KQ253_06015	COG1064	alcohol dehydrogenase
KQ253_06025	COG2207	Transcriptional regulator
KQ253_06030	COG2084	Dehydrogenase
KQ253_06040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KQ253_06045	COG0583	DNA-binding transcription factor activity
KQ253_06055	COG0129	dihydroxy-acid dehydratase activity
KQ253_06060	COG1012	belongs to the aldehyde dehydrogenase family
KQ253_06065	COG1846	Transcriptional regulator
KQ253_06070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KQ253_06075	COG1960	acyl-CoA dehydrogenase activity
KQ253_06080	COG0477	Major facilitator Superfamily
KQ253_06090	COG2826	transposase and inactivated derivatives, IS30 family
KQ253_06105	COG3971	2-oxopent-4-enoate hydratase activity
KQ253_06115	COG3384	dioxygenase
KQ253_06120	COG1012	belongs to the aldehyde dehydrogenase family
KQ253_06130	COG0179	Fumarylacetoacetate (FAA) hydrolase
KQ253_06140	COG2814	Major facilitator Superfamily
KQ253_06145	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KQ253_06160	COG1012	belongs to the aldehyde dehydrogenase family
KQ253_06185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KQ253_06205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KQ253_06225	COG1566	PFAM secretion protein HlyD family protein
KQ253_06245	COG3210	domain, Protein
KQ253_06250	COG2831	hemolysin activation secretion protein
KQ253_06270	COG0583	DNA-binding transcription factor activity
KQ253_06290	COG2188	Transcriptional regulator
KQ253_06345	COG1473	amidohydrolase
KQ253_06355	COG0475	glutathione-regulated potassium exporter activity
KQ253_06355	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KQ253_06365	COG0583	DNA-binding transcription factor activity
KQ253_06370	COG1335	isochorismatase
KQ253_06380	COG1309	transcriptional regulator
KQ253_06410	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KQ253_06420	COG1902	pentaerythritol trinitrate reductase activity
KQ253_06420	COG0446	pyridine nucleotide-disulphide oxidoreductase
KQ253_06425	COG1846	Transcriptional regulator
KQ253_06445	COG0753	catalase activity
KQ253_06460	COG1012	belongs to the aldehyde dehydrogenase family
KQ253_06475	COG3162	membrane
KQ253_06485	COG3829	transcription factor binding
KQ253_06490	COG1028	Short-chain dehydrogenase reductase Sdr
KQ253_06495	COG1960	acyl-CoA dehydrogenase activity
KQ253_06510	COG3231	kanamycin kinase activity
KQ253_06515	COG1012	belongs to the aldehyde dehydrogenase family
KQ253_06535	COG2186	Transcriptional regulator
KQ253_06545	COG0583	DNA-binding transcription factor activity
KQ253_06550	COG4948	Mandelate Racemase Muconate Lactonizing
KQ253_06555	COG4829	muconolactone delta-isomerase
KQ253_06565	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KQ253_06570	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KQ253_06575	COG0183	Belongs to the thiolase family
KQ253_06580	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KQ253_06585	COG1012	belongs to the aldehyde dehydrogenase family
KQ253_06595	COG3733	amine oxidase
KQ253_06605	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KQ253_06615	COG1028	Short-chain dehydrogenase reductase Sdr
KQ253_06625	COG4638	Rieske (2fe-2S)
KQ253_06645	COG0154	amidase activity
KQ253_06655	COG2814	Major facilitator Superfamily
KQ253_06680	COG1960	acyl-CoA dehydrogenase activity
KQ253_06685	COG0583	DNA-binding transcription factor activity
KQ253_06690	COG1414	Transcriptional regulator
KQ253_06705	COG2391	methyltransferase activity
KQ253_06715	COG4993	Dehydrogenase
KQ253_06720	COG3659	wide pore channel activity
KQ253_06725	COG3420	alginic acid biosynthetic process
KQ253_06730	COG0710	3-dehydroquinate dehydratase activity
KQ253_06735	COG3485	protocatechuate 3,4-dioxygenase
KQ253_06740	COG3485	protocatechuate 3,4-dioxygenase
KQ253_06745	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KQ253_06750	COG2271	Major facilitator Superfamily
KQ253_06755	COG0596	Alpha beta hydrolase
KQ253_06760	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KQ253_06765	COG0183	Belongs to the thiolase family
KQ253_06770	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KQ253_06775	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KQ253_06785	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KQ253_06790	COG2323	membrane
KQ253_06835	COG1902	pentaerythritol trinitrate reductase activity
KQ253_06835	COG0446	pyridine nucleotide-disulphide oxidoreductase
KQ253_06860	COG0542	response to heat
KQ253_06865	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KQ253_06895	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KQ253_06900	COG0569	domain protein
KQ253_06905	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KQ253_06925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KQ253_06935	COG1585	Membrane protein implicated in regulation of membrane protease activity
KQ253_06950	COG1294	oxidase, subunit
KQ253_06955	COG4890	Cyd operon protein YbgT
KQ253_06970	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
KQ253_06980	COG0552	protein localization to endoplasmic reticulum
KQ253_07005	COG0517	IMP dehydrogenase activity
KQ253_07005	COG0516	GMP reductase activity
KQ253_07010	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KQ253_07015	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KQ253_07025	COG0583	DNA-binding transcription factor activity
KQ253_07030	COG0024	Methionine aminopeptidase
KQ253_07060	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KQ253_07060	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KQ253_07065	COG1105	Belongs to the carbohydrate kinase PfkB family
KQ253_07070	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KQ253_07070	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KQ253_07070	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KQ253_07090	COG3300	MHYT domain
KQ253_07090	COG5001	Diguanylate cyclase
KQ253_07105	COG2135	peptidase activity
KQ253_07110	COG0659	secondary active sulfate transmembrane transporter activity
KQ253_07130	COG1113	amino acid transport
KQ253_07140	COG1522	sequence-specific DNA binding
KQ253_07165	COG1011	Hydrolase
KQ253_07170	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KQ253_07180	COG2137	regulation of response to DNA damage stimulus
KQ253_07195	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KQ253_07230	COG0575	Belongs to the CDS family
KQ253_07235	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KQ253_07260	COG3852	Histidine kinase
KQ253_07265	COG2204	response regulator
KQ253_07320	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KQ253_07325	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KQ253_07345	COG0697	spore germination
KQ253_07350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KQ253_07360	COG0303	'Molybdopterin
KQ253_07365	COG0521	Mo-molybdopterin cofactor biosynthetic process
KQ253_07365	COG0315	cyclic pyranopterin monophosphate synthase activity
KQ253_07380	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KQ253_07385	COG0243	molybdopterin cofactor binding
KQ253_07395	COG0243	molybdopterin cofactor binding
KQ253_07400	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KQ253_07405	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KQ253_07405	COG2146	nitrite reductase [NAD(P)H] activity
KQ253_07415	COG0745	RESPONSE REGULATOR receiver
KQ253_07420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KQ253_07420	COG1116	anion transmembrane transporter activity
KQ253_07435	COG0511	ligase activity, forming carbon-carbon bonds
KQ253_07480	COG2026	Addiction module toxin, RelE StbE family
KQ253_07650	COG2826	transposase and inactivated derivatives, IS30 family
KQ253_07680	COG1484	DNA-dependent DNA replication
KQ253_07775	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KQ253_07835	COG0069	glutamate synthase activity
KQ253_07855	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KQ253_07865	COG1454	alcohol dehydrogenase
KQ253_07870	COG0824	Thioesterase
KQ253_07880	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KQ253_07895	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KQ253_07900	COG2030	dehydratase
KQ253_07910	COG0183	Belongs to the thiolase family
KQ253_07920	COG0583	DNA-binding transcription factor activity
KQ253_07925	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KQ253_07935	COG1522	sequence-specific DNA binding
KQ253_07940	COG3135	benzoate transporter
KQ253_07950	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KQ253_07970	COG0589	response to stress
KQ253_07975	COG0488	(ABC) transporter
KQ253_07995	COG4773	Receptor
KQ253_08025	COG0668	transmembrane transport
KQ253_08035	COG1309	transcriptional regulator
KQ253_08045	COG2826	transposase and inactivated derivatives, IS30 family
KQ253_08055	COG1605	Chorismate mutase
KQ253_08075	COG0308	aminopeptidase N
KQ253_08100	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KQ253_08105	COG1454	alcohol dehydrogenase
KQ253_08125	COG0531	amino acid
KQ253_08130	COG4303	Ethanolamine ammonia lyase large subunit
KQ253_08135	COG4302	ethanolamine ammonia-lyase activity
KQ253_08140	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KQ253_08140	COG0519	Catalyzes the synthesis of GMP from XMP
KQ253_08145	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KQ253_08170	COG0697	spore germination
KQ253_08175	COG1923	regulation of RNA biosynthetic process
KQ253_08185	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KQ253_08190	COG0802	atpase or kinase
KQ253_08210	COG1187	pseudouridine synthase activity
KQ253_08225	COG0583	DNA-binding transcription factor activity
KQ253_08265	COG0776	regulation of translation
KQ253_08295	COG3409	Peptidoglycan-binding domain 1 protein
KQ253_08295	COG3267	Type II secretory pathway component ExeA
KQ253_08320	COG0681	Belongs to the peptidase S26 family
KQ253_08355	COG4373	Mu-like prophage FluMu protein gp28
KQ253_08370	COG4383	Mu-like prophage protein gp29
KQ253_08375	COG2369	cell adhesion
KQ253_08380	COG5005	Phage virion morphogenesis
KQ253_08395	COG4397	Mu-like prophage major head subunit gpT
KQ253_08490	COG2814	Major facilitator Superfamily
KQ253_08495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KQ253_08520	COG0729	surface antigen
KQ253_08540	COG0174	glutamine synthetase
KQ253_08545	COG0745	RESPONSE REGULATOR receiver
KQ253_08550	COG2205	protein histidine kinase activity
KQ253_08560	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KQ253_08565	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KQ253_08590	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KQ253_08595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KQ253_08600	COG1960	acyl-CoA dehydrogenase activity
KQ253_08630	COG0583	DNA-binding transcription factor activity
KQ253_08645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KQ253_08655	COG3658	cytochrome
KQ253_08660	COG1215	transferase activity, transferring glycosyl groups
KQ253_08665	COG1649	PFAM Uncharacterised BCR, COG1649
KQ253_08665	COG0726	polysaccharide deacetylase
KQ253_08690	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KQ253_08695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KQ253_08705	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KQ253_08730	COG0305	Participates in initiation and elongation during chromosome replication
KQ253_08735	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KQ253_08755	COG2308	Evidence 4 Homologs of previously reported genes of
KQ253_08785	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KQ253_08790	COG0138	bifunctional purine biosynthesis protein purh
KQ253_08795	COG0151	Belongs to the GarS family
KQ253_08800	COG1464	Belongs to the NlpA lipoprotein family
KQ253_08805	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KQ253_08810	COG2011	ABC-type metal ion transport system permease component
KQ253_08815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KQ253_08825	COG1301	dicarboxylic acid transport
KQ253_08855	COG1794	racemase activity, acting on amino acids and derivatives
KQ253_08865	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KQ253_08865	COG3008	intermembrane lipid transfer
KQ253_08870	COG2995	paraquat-inducible protein a
KQ253_08880	COG2985	domain, Protein
KQ253_08905	COG0477	Major facilitator Superfamily
KQ253_08950	COG2186	Transcriptional regulator
KQ253_08960	COG0786	glutamate:sodium symporter activity
KQ253_08965	COG3243	poly(R)-hydroxyalkanoic acid synthase
KQ253_08990	COG3111	PFAM Bacterial OB fold (BOF) protein
KQ253_09075	COG2831	hemolysin activation secretion protein
KQ253_09130	COG1610	YqeY-like protein
KQ253_09160	COG1286	toxin biosynthetic process
KQ253_09190	COG0778	Nitroreductase
KQ253_09200	COG0513	Belongs to the DEAD box helicase family
KQ253_09220	COG2363	Small membrane protein
KQ253_09250	COG1234	tRNA 3'-trailer cleavage
KQ253_09255	COG2195	Cleaves the N-terminal amino acid of tripeptides
KQ253_09265	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KQ253_09275	COG2819	hydrolase of the alpha beta superfamily
KQ253_09280	COG1960	acyl-CoA dehydrogenase activity
KQ253_09285	COG1301	dicarboxylic acid transport
KQ253_09290	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KQ253_09295	COG3139	Protein of unknown function (DUF1315)
KQ253_09300	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KQ253_09305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KQ253_09315	COG0494	nUDIX hydrolase
KQ253_09325	COG0642	Histidine kinase
KQ253_09340	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KQ253_09350	COG1720	tRNA m6t6A37 methyltransferase activity
KQ253_09365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KQ253_09370	COG0826	peptidase U32
KQ253_09375	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KQ253_09390	COG4598	ABC transporter
KQ253_09395	COG4160	amino acid transport
KQ253_09400	COG4215	(ABC) transporter
KQ253_09415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KQ253_09495	COG0739	heme binding
KQ253_09505	COG3561	AntA/AntB antirepressor
KQ253_09615	COG3728	DNA packaging
KQ253_09790	COG0582	viral genome integration into host DNA
KQ253_09795	COG1131	(ABC) transporter
KQ253_09800	COG0842	Transport permease protein
KQ253_09815	COG0772	Belongs to the SEDS family
KQ253_09820	COG2951	lytic endotransglycosylase activity
KQ253_09845	COG2207	Transcriptional regulator
KQ253_09860	COG0052	Belongs to the universal ribosomal protein uS2 family
KQ253_09865	COG0024	Methionine aminopeptidase
KQ253_09875	COG2223	nitrite transmembrane transporter activity
KQ253_09885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KQ253_09890	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KQ253_09895	COG1960	acyl-CoA dehydrogenase activity
KQ253_09910	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KQ253_09915	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KQ253_09920	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KQ253_09940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KQ253_09945	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KQ253_09950	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KQ253_09985	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KQ253_09995	COG0174	glutamine synthetase
KQ253_10010	COG0512	Glutamine amidotransferase of anthranilate synthase
KQ253_10045	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KQ253_10055	COG0302	gtp cyclohydrolase
KQ253_10070	COG0659	secondary active sulfate transmembrane transporter activity
KQ253_10075	COG0589	response to stress
KQ253_10090	COG3328	transposase activity
KQ253_10140	COG3739	integral membrane protein
KQ253_10155	COG1169	isochorismate synthase
KQ253_10165	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KQ253_10170	COG1132	(ABC) transporter
KQ253_10175	COG1132	(ABC) transporter
KQ253_10185	COG1535	isochorismatase
KQ253_10185	COG3433	isochorismatase activity
KQ253_10190	COG1021	2,3-dihydroxybenzoate-AMP ligase
KQ253_10195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KQ253_10205	COG4774	siderophore transport
KQ253_10210	COG4607	ABC-type enterochelin transport system periplasmic component
KQ253_10215	COG4604	ABC transporter, ATP-binding protein
KQ253_10220	COG4605	iron ion homeostasis
KQ253_10225	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KQ253_10230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KQ253_10245	COG2964	Protein conserved in bacteria
KQ253_10255	COG1741	Belongs to the pirin family
KQ253_10280	COG2879	small protein
KQ253_10285	COG1966	Carbon starvation protein
KQ253_10335	COG2211	Major facilitator Superfamily
KQ253_10340	COG1067	ATP-dependent peptidase activity
KQ253_10345	COG0583	DNA-binding transcription factor activity
KQ253_10370	COG1686	Belongs to the peptidase S11 family
KQ253_10375	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KQ253_10410	COG0616	signal peptide processing
KQ253_10415	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KQ253_10425	COG0573	inorganic phosphate transmembrane transporter activity
KQ253_10430	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KQ253_10435	COG1113	amino acid transport
KQ253_10440	COG3961	Belongs to the TPP enzyme family
KQ253_10445	COG1522	sequence-specific DNA binding
KQ253_10455	COG0076	glutamate decarboxylase activity
KQ253_10460	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KQ253_10470	COG1309	transcriptional regulator
KQ253_10485	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KQ253_10520	COG0352	thiamine-phosphate diphosphorylase activity
KQ253_10545	COG0612	Peptidase, M16
KQ253_10555	COG1823	symporter activity
KQ253_10560	COG0583	DNA-binding transcription factor activity
KQ253_10565	COG0477	Major facilitator Superfamily
KQ253_10590	COG1187	pseudouridine synthase activity
KQ253_10605	COG1686	Belongs to the peptidase S11 family
KQ253_10610	COG1252	NADH dehydrogenase
KQ253_10620	COG0415	Belongs to the DNA photolyase family
KQ253_10635	COG1215	transferase activity, transferring glycosyl groups
KQ253_10665	COG2070	2-Nitropropane dioxygenase
KQ253_10720	COG0556	nucleotide-excision repair
KQ253_10740	COG0436	Aminotransferase
KQ253_10770	COG4221	oxidoreductase activity
KQ253_10780	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KQ253_10785	COG1381	Involved in DNA repair and RecF pathway recombination
KQ253_10795	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KQ253_10810	COG0681	Belongs to the peptidase S26 family
KQ253_10825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KQ253_10845	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KQ253_10850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KQ253_10855	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KQ253_10865	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KQ253_10870	COG4208	sulfate ABC transporter
KQ253_10875	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KQ253_10880	COG0583	DNA-binding transcription factor activity
KQ253_10885	COG4625	pathogenesis
KQ253_10900	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KQ253_10915	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KQ253_10925	COG1051	belongs to the nudix hydrolase family
KQ253_10925	COG1056	cytidyltransferase-related domain
KQ253_10930	COG1024	Enoyl-CoA hydratase
KQ253_10945	COG2814	Major facilitator Superfamily
KQ253_10950	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KQ253_10950	COG0047	phosphoribosylformylglycinamidine synthase activity
KQ253_10970	COG1473	amidohydrolase
KQ253_10975	COG0824	Thioesterase
KQ253_10995	COG0823	Involved in the tonB-independent uptake of proteins
KQ253_11015	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KQ253_11050	COG0628	permease
KQ253_11060	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KQ253_11065	COG0596	Alpha beta hydrolase
KQ253_11070	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KQ253_11070	COG0616	signal peptide processing
KQ253_11080	COG0658	competence protein
KQ253_11080	COG2333	competence protein COMEC
KQ253_11085	COG1136	(ABC) transporter
KQ253_11090	COG4591	ABC-type transport system involved in lipoprotein release permease component
KQ253_11125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KQ253_11145	COG0463	Glycosyl transferase, family 2
KQ253_11175	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KQ253_11180	COG1280	lysine exporter protein (LysE YggA)
KQ253_11190	COG0019	diaminopimelate decarboxylase activity
KQ253_11200	COG1113	amino acid transport
KQ253_11215	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KQ253_11225	COG3339	Conserved Protein
KQ253_11230	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KQ253_11235	COG0243	molybdopterin cofactor binding
KQ253_11240	COG1929	Belongs to the glycerate kinase type-1 family
KQ253_11255	COG0778	Nitroreductase
KQ253_11320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KQ253_11335	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KQ253_11355	COG0741	lytic transglycosylase activity
KQ253_11375	COG0584	glycerophosphoryl diester phosphodiesterase
KQ253_11415	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KQ253_11420	COG1597	lipid kinase activity
KQ253_11435	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KQ253_11440	COG0477	Major facilitator Superfamily
KQ253_11490	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KQ253_11495	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KQ253_11520	COG0505	Belongs to the CarA family
KQ253_11540	COG0589	response to stress
KQ253_11555	COG2843	Capsule synthesis protein
KQ253_11570	COG2826	transposase and inactivated derivatives, IS30 family
KQ253_11580	COG2321	neutral zinc metallopeptidase
KQ253_11585	COG2354	Protein conserved in bacteria
KQ253_11605	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KQ253_11630	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KQ253_11635	COG1053	succinate dehydrogenase
KQ253_11640	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KQ253_11680	COG2921	Belongs to the UPF0250 family
KQ253_11685	COG0321	lipoyl(octanoyl) transferase activity
KQ253_11700	COG0531	amino acid
KQ253_11710	COG1733	regulation of RNA biosynthetic process
KQ253_11715	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KQ253_11720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KQ253_11720	COG1648	precorrin-2 dehydrogenase activity
KQ253_11735	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KQ253_11760	COG0215	cysteine-tRNA ligase activity
KQ253_11765	COG0671	phosphoesterase, PA-phosphatase related
KQ253_11770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KQ253_11780	COG1538	Outer membrane efflux protein
KQ253_11785	COG0393	Putative heavy-metal-binding
KQ253_11790	COG0393	Putative heavy-metal-binding
KQ253_11800	COG1028	Short-chain dehydrogenase reductase Sdr
KQ253_11810	COG0525	valine-tRNA ligase activity
KQ253_11830	COG2826	transposase and inactivated derivatives, IS30 family
KQ253_11840	COG0583	DNA-binding transcription factor activity
KQ253_11845	COG0004	ammonium transporteR
KQ253_11855	COG0642	Histidine kinase
KQ253_11860	COG0745	RESPONSE REGULATOR receiver
KQ253_11865	COG2194	sulfuric ester hydrolase activity
KQ253_11885	COG1752	Esterase of the alpha-beta hydrolase superfamily
KQ253_11900	COG2315	Protein conserved in bacteria
KQ253_11905	COG0142	geranyltranstransferase activity
KQ253_11910	COG2828	Protein conserved in bacteria
KQ253_11915	COG1113	amino acid transport
KQ253_11940	COG2207	Transcriptional regulator
KQ253_11965	COG2249	NAD(P)H dehydrogenase (quinone) activity
KQ253_11975	COG0560	Phosphoserine phosphatase
KQ253_11985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KQ253_11995	COG1530	ribonuclease E activity
KQ253_12000	COG0424	maF-like protein
KQ253_12005	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KQ253_12010	COG1792	Involved in formation and maintenance of cell shape
KQ253_12015	COG1077	Cell shape determining protein MreB Mrl
KQ253_12020	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KQ253_12030	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KQ253_12055	COG3590	peptidase
KQ253_12060	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
KQ253_12065	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KQ253_12070	COG1752	Esterase of the alpha-beta hydrolase superfamily
KQ253_12075	COG1115	amino acid carrier protein
KQ253_12095	COG2814	Major facilitator Superfamily
KQ253_12100	COG1289	transmembrane transporter activity
KQ253_12110	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KQ253_12150	COG1376	ErfK ybiS ycfS ynhG family protein
KQ253_12155	COG2832	Protein of unknown function (DUF454)
KQ253_12165	COG5510	response to toxic substance
KQ253_12185	COG0840	transmembrane signaling receptor activity
KQ253_12225	COG3422	double-strand break repair
KQ253_12230	COG2824	Alkylphosphonate utilization operon protein PhnA
KQ253_12235	COG3189	MarR family transcriptional regulator
KQ253_12245	COG0354	folic acid binding
KQ253_12250	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KQ253_12260	COG0679	Auxin Efflux Carrier
KQ253_12265	COG1902	pentaerythritol trinitrate reductase activity
KQ253_12270	COG4772	TonB-dependent receptor
KQ253_12275	COG2094	Belongs to the DNA glycosylase MPG family
KQ253_12300	COG1217	gtp-binding protein TYPA
KQ253_12305	COG2233	PERMEase
KQ253_12315	COG0833	amino acid
KQ253_12320	COG1690	Belongs to the RtcB family
KQ253_12330	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KQ253_12330	COG2885	chlorophyll binding
KQ253_12340	COG0183	Belongs to the thiolase family
KQ253_12360	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KQ253_12380	COG2207	Transcriptional regulator
KQ253_12385	COG0183	Belongs to the thiolase family
KQ253_12415	COG1272	protein, Hemolysin III
KQ253_12420	COG0477	Major facilitator Superfamily
KQ253_12435	COG0450	alkyl hydroperoxide reductase
KQ253_12455	COG0285	dihydrofolate synthase activity
KQ253_12500	COG4206	TonB-dependent receptor
KQ253_12505	COG2096	Adenosyltransferase
KQ253_12510	COG0584	glycerophosphoryl diester phosphodiesterase
KQ253_12525	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KQ253_12530	COG0745	RESPONSE REGULATOR receiver
KQ253_12535	COG2205	protein histidine kinase activity
KQ253_12545	COG1960	acyl-CoA dehydrogenase activity
KQ253_12550	COG1960	acyl-CoA dehydrogenase activity
KQ253_12625	COG0438	transferase activity, transferring glycosyl groups
KQ253_12630	COG0463	Glycosyl transferase, family 2
KQ253_12635	COG0726	polysaccharide deacetylase
KQ253_12655	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KQ253_12710	COG1862	Preprotein translocase
KQ253_12720	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KQ253_12725	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KQ253_12735	COG3781	membrane
KQ253_12740	COG0613	PHP domain protein
KQ253_12750	COG2350	Protein conserved in bacteria
KQ253_12780	COG1607	acyl-coa hydrolase
KQ253_12845	COG2199	diguanylate cyclase activity
KQ253_12855	COG1408	metallophosphoesterase
KQ253_12860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KQ253_12870	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KQ253_12890	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KQ253_12895	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KQ253_12910	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KQ253_12920	COG2969	positive regulation of protein catabolic process
KQ253_12940	COG1960	acyl-CoA dehydrogenase activity
KQ253_12945	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KQ253_12960	COG1309	transcriptional regulator
KQ253_12965	COG1960	acyl-CoA dehydrogenase activity
KQ253_13010	COG1183	phosphatidylcholine synthase activity
KQ253_13015	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KQ253_13045	COG0741	lytic transglycosylase activity
KQ253_13045	COG1196	nuclear chromosome segregation
KQ253_13045	COG0739	heme binding
KQ253_13055	COG1702	phosphate starvation-inducible protein PhoH
KQ253_13090	COG1295	ribonuclease BN
KQ253_13095	COG0697	spore germination
KQ253_13105	COG0179	Fumarylacetoacetate (FAA) hydrolase
KQ253_13150	COG0557	exoribonuclease II activity
KQ253_13155	COG0339	signal peptide processing
KQ253_13160	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KQ253_13190	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KQ253_13195	COG1960	acyl-CoA dehydrogenase activity
KQ253_13350	COG0626	cystathionine gamma-synthase activity
KQ253_13355	COG0433	COG0433 Predicted ATPase
KQ253_13360	COG1017	nitric oxide dioxygenase activity
KQ253_13360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KQ253_13365	COG1959	2 iron, 2 sulfur cluster binding
KQ253_13380	COG1301	dicarboxylic acid transport
KQ253_13385	COG1946	Acyl-CoA thioesterase
KQ253_13405	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KQ253_13410	COG1040	competence protein
KQ253_13415	COG0494	nUDIX hydrolase
KQ253_13425	COG0598	Magnesium transport protein CorA
KQ253_13435	COG2854	intermembrane phospholipid transfer
KQ253_13445	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KQ253_13450	COG1127	ABC transporter
KQ253_13460	COG0513	Belongs to the DEAD box helicase family
KQ253_13480	COG0408	coproporphyrinogen oxidase activity
KQ253_13495	COG1960	acyl-CoA dehydrogenase activity
KQ253_13505	COG1983	PspC domain protein
KQ253_13510	COG0517	IMP dehydrogenase activity
KQ253_13545	COG1106	Psort location Cytoplasmic, score
KQ253_13565	COG0583	DNA-binding transcription factor activity
KQ253_13605	COG1012	belongs to the aldehyde dehydrogenase family
KQ253_13615	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KQ253_13620	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KQ253_13625	COG0833	amino acid
KQ253_13655	COG1192	Involved in chromosome partitioning
KQ253_13660	COG0628	permease
KQ253_13670	COG1289	transmembrane transporter activity
KQ253_13685	COG2249	NAD(P)H dehydrogenase (quinone) activity
KQ253_13690	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KQ253_13705	COG0277	FAD linked oxidase domain protein
KQ253_13710	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KQ253_13735	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KQ253_13740	COG5380	lipid catabolic process
KQ253_13760	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KQ253_13810	COG0194	GDP metabolic process
KQ253_13825	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KQ253_13845	COG3307	-O-antigen
KQ253_13865	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KQ253_13870	COG1704	LemA family
KQ253_13880	COG0493	'glutamate synthase
KQ253_13885	COG0069	glutamate synthase activity
KQ253_13885	COG0070	glutamate synthase
KQ253_13885	COG0067	glutamate synthase
KQ253_13935	COG2226	methyltransferase
KQ253_13950	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KQ253_13955	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KQ253_14015	COG0833	amino acid
KQ253_14100	COG0488	(ABC) transporter
KQ253_14110	COG4221	oxidoreductase activity
KQ253_14115	COG0659	secondary active sulfate transmembrane transporter activity
KQ253_14140	COG0427	acetyl-CoA hydrolase
KQ253_14170	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KQ253_14200	COG2329	Antibiotic biosynthesis monooxygenase
KQ253_14215	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KQ253_14285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KQ253_14345	COG2249	NAD(P)H dehydrogenase (quinone) activity
KQ253_14350	COG1733	regulation of RNA biosynthetic process
KQ253_14365	COG2826	transposase and inactivated derivatives, IS30 family
KQ253_14395	COG0667	Aldo Keto reductase
KQ253_14415	COG0583	DNA-binding transcription factor activity
KQ253_14420	COG2814	Major facilitator Superfamily
KQ253_14430	COG1113	amino acid transport
KQ253_14485	COG1335	isochorismatase
KQ253_14495	COG1012	belongs to the aldehyde dehydrogenase family
KQ253_14520	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KQ253_14535	COG2814	Major facilitator Superfamily
KQ253_14545	COG0351	phosphomethylpyrimidine kinase
KQ253_14545	COG0352	thiamine-phosphate diphosphorylase activity
KQ253_14545	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KQ253_14565	COG1309	transcriptional regulator
KQ253_14570	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KQ253_14595	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KQ253_14605	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KQ253_14610	COG3162	membrane
KQ253_14615	COG0784	Response regulator, receiver
KQ253_14615	COG2198	Histidine kinase
KQ253_14615	COG2205	protein histidine kinase activity
KQ253_14640	COG1522	sequence-specific DNA binding
KQ253_14645	COG1335	isochorismatase
KQ253_14650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KQ253_14660	COG0668	transmembrane transport
KQ253_14665	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KQ253_14670	COG1519	Transferase
KQ253_14675	COG1902	pentaerythritol trinitrate reductase activity
KQ253_14695	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KQ253_14725	COG0426	domain, Protein
KQ253_14725	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KQ253_14730	COG4774	siderophore transport
KQ253_14735	COG2119	membrane
KQ253_14745	COG0508	dehydrogenase complex catalyzes the overall conversion of
KQ253_14755	COG4942	peptidase
KQ253_14770	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KQ253_14780	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KQ253_14800	COG0189	ligase activity
KQ253_14820	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KQ253_14835	COG0708	Exodeoxyribonuclease III
KQ253_14840	COG1393	Belongs to the ArsC family
KQ253_14855	COG3706	GGDEF domain
KQ253_14890	COG2351	hydroxyisourate hydrolase activity
KQ253_14895	COG2233	PERMEase
KQ253_14905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KQ253_14915	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
KQ253_14925	COG3150	esterase
KQ253_14980	COG2918	glutathione biosynthetic process
KQ253_14995	COG2733	membrane
KQ253_15000	COG0436	Aminotransferase
KQ253_15005	COG0534	Mate efflux family protein
KQ253_15090	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KQ253_15095	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KQ253_15105	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KQ253_15205	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KQ253_15220	COG0010	Belongs to the arginase family
KQ253_15250	COG2188	Transcriptional regulator
KQ253_15260	COG0523	cobalamin synthesis protein
KQ253_15270	COG1113	amino acid transport
KQ253_15280	COG0625	glutathione transferase activity
KQ253_15300	COG1683	Conserved Protein
KQ253_15305	COG0534	Mate efflux family protein
KQ253_15310	COG0385	Bile acid
KQ253_15315	COG1335	isochorismatase
KQ253_15320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KQ253_15340	COG2116	formate transmembrane transporter activity
KQ253_15345	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KQ253_15350	COG2133	pyrroloquinoline quinone binding
KQ253_15355	COG2983	Belongs to the UPF0260 family
KQ253_15375	COG1194	a g-specific adenine glycosylase
KQ253_15390	COG2818	Glycosylase
KQ253_15395	COG1064	alcohol dehydrogenase
KQ253_15400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KQ253_15415	COG0583	DNA-binding transcription factor activity
KQ253_15420	COG0656	L-ascorbic acid biosynthetic process
KQ253_15425	COG2814	Major facilitator Superfamily
KQ253_15460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KQ253_15475	COG2233	PERMEase
KQ253_15480	COG0583	DNA-binding transcription factor activity
KQ253_15515	COG0733	neurotransmitter:sodium symporter activity
KQ253_15555	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KQ253_15560	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KQ253_15565	COG0596	Alpha beta hydrolase
KQ253_15590	COG0488	(ABC) transporter
KQ253_15595	COG0586	Pfam SNARE associated Golgi protein
KQ253_15605	COG0187	DNA topoisomerase II activity
KQ253_15615	COG0592	DNA-directed DNA polymerase activity
KQ253_15645	COG0706	membrane insertase activity
KQ253_15660	COG1230	cation diffusion facilitator family transporter
KQ253_15665	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KQ253_15680	COG0402	S-adenosylhomocysteine deaminase activity
KQ253_15690	COG0754	glutathionylspermidine amidase activity
KQ253_15700	COG0861	Integral membrane protein TerC family
KQ253_15705	COG0671	phosphoesterase, PA-phosphatase related
KQ253_15740	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KQ253_15755	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KQ253_15760	COG2951	lytic endotransglycosylase activity
KQ253_15810	COG0657	acetylesterase activity
KQ253_15815	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KQ253_15855	COG1047	Peptidyl-prolyl cis-trans
KQ253_15865	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KQ253_15870	COG0196	riboflavin kinase activity
KQ253_15880	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KQ253_15885	COG1309	transcriptional regulator
KQ253_15890	COG1116	anion transmembrane transporter activity
KQ253_15895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KQ253_15900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KQ253_15905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KQ253_15910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KQ253_15930	COG1028	Short-chain dehydrogenase reductase Sdr
KQ253_15935	COG0546	phosphoglycolate phosphatase activity
KQ253_15995	COG3023	N-Acetylmuramoyl-L-alanine amidase
KQ253_16000	COG0728	peptidoglycan biosynthetic process
KQ253_16025	COG1596	polysaccharide export
KQ253_16030	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KQ253_16085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KQ253_16090	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KQ253_16095	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KQ253_16110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KQ253_16115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KQ253_16125	COG2186	Transcriptional regulator
KQ253_16135	COG0277	FAD linked oxidase domain protein
KQ253_16140	COG1448	Aminotransferase
KQ253_16150	COG1802	Transcriptional regulator
KQ253_16165	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KQ253_16185	COG1051	belongs to the nudix hydrolase family
KQ253_16220	COG0564	pseudouridine synthase activity
KQ253_16260	COG0251	oxidation-reduction process
KQ253_16265	COG1113	amino acid transport
KQ253_16270	COG1113	amino acid transport
KQ253_16290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KQ253_16295	COG1960	acyl-CoA dehydrogenase activity
KQ253_16300	COG1024	Enoyl-CoA hydratase
KQ253_16305	COG1024	Enoyl-CoA hydratase
KQ253_16325	COG0271	Belongs to the BolA IbaG family
KQ253_16335	COG1192	Involved in chromosome partitioning
KQ253_16350	COG0586	Pfam SNARE associated Golgi protein
KQ253_16355	COG2259	Doxx family
KQ253_16360	COG4399	Belongs to the UPF0754 family
KQ253_16365	COG0519	Catalyzes the synthesis of GMP from XMP
KQ253_16365	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KQ253_16410	COG0281	malic enzyme
KQ253_16425	COG2837	iron assimilation
KQ253_16430	COG1280	lysine exporter protein (LysE YggA)
KQ253_16435	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KQ253_16440	COG1121	(ABC) transporter
KQ253_16505	COG0386	Belongs to the glutathione peroxidase family
KQ253_16520	COG1309	transcriptional regulator
KQ253_16525	COG0697	spore germination
KQ253_16535	COG0758	DNA mediated transformation
KQ253_16570	COG1309	transcriptional regulator
KQ253_16605	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KQ253_16615	COG0655	NAD(P)H dehydrogenase (quinone) activity
KQ253_16660	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KQ253_16670	COG2814	Major facilitator Superfamily
KQ253_16680	COG1253	flavin adenine dinucleotide binding
KQ253_16690	COG2860	membrane
KQ253_16695	COG0477	Major facilitator Superfamily
KQ253_16705	COG0318	PFAM AMP-dependent synthetase and ligase
KQ253_16725	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KQ253_16740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KQ253_16750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KQ253_16755	COG0606	chelatase, subunit chli
KQ253_16785	COG3328	transposase activity
KQ253_16800	COG0589	response to stress
KQ253_16805	COG0659	secondary active sulfate transmembrane transporter activity
KQ253_16815	COG0606	chelatase, subunit chli
KQ253_16825	COG0347	Belongs to the P(II) protein family
KQ253_16830	COG0004	ammonium transporteR
KQ253_16840	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KQ253_16840	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KQ253_16880	COG0795	lipopolysaccharide-transporting ATPase activity
KQ253_16885	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KQ253_16890	COG0793	Belongs to the peptidase S41A family
KQ253_16905	COG2197	response regulator
KQ253_16915	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KQ253_16925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KQ253_16930	COG4974	Belongs to the 'phage' integrase family
KQ253_16955	COG0772	Belongs to the SEDS family
KQ253_16960	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KQ253_16965	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KQ253_16970	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KQ253_16995	COG0697	spore germination
KQ253_17000	COG1538	Outer membrane efflux protein
KQ253_17020	COG3275	phosphorelay sensor kinase activity
KQ253_17030	COG0181	hydroxymethylbilane synthase activity
KQ253_17085	COG1716	ATPase activity
KQ253_17090	COG0546	phosphoglycolate phosphatase activity
KQ253_17185	COG0596	Alpha beta hydrolase
KQ253_17190	COG2056	Na+-H+ antiporter family
KQ253_17205	COG0326	Molecular chaperone. Has ATPase activity
KQ253_17220	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KQ253_17285	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KQ253_17290	COG2169	Transcriptional regulator
KQ253_17290	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KQ253_17320	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KQ253_17330	COG0497	DNA recombination
KQ253_17345	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KQ253_17355	COG0237	dephospho-CoA kinase activity
KQ253_17405	COG0195	Participates in both transcription termination and antitermination
KQ253_17420	COG1320	monovalent cation:proton antiporter activity
KQ253_17425	COG2212	antiporter activity
KQ253_17430	COG1863	multisubunit Na H antiporter MnhE subunit
KQ253_17435	COG0651	ATP synthesis coupled electron transport
KQ253_17440	COG1006	Multisubunit Na H antiporter MnhC subunit
KQ253_17445	COG2111	Na H antiporter
KQ253_17445	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KQ253_17460	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KQ253_17470	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KQ253_17480	COG2226	methyltransferase
KQ253_17500	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KQ253_17505	COG1074	ATP-dependent DNA helicase activity
KQ253_17510	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KQ253_17515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KQ253_17530	COG0598	Magnesium transport protein CorA
KQ253_17535	COG0789	Transcriptional regulator
KQ253_17540	COG0484	heat shock protein binding
KQ253_17555	COG0475	glutathione-regulated potassium exporter activity
KQ253_17555	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KQ253_17560	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KQ253_17580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KQ253_17590	COG4535	Mg2 and Co2 transporter CorC
KQ253_17595	COG0425	Belongs to the sulfur carrier protein TusA family
KQ253_17600	COG0644	oxidoreductase
KQ253_17600	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
KQ253_17610	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KQ253_17625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KQ253_17630	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KQ253_17640	COG0493	'glutamate synthase
KQ253_17640	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
KQ253_17670	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KQ253_17685	COG0534	Mate efflux family protein
KQ253_17700	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KQ253_17705	COG1028	Short-chain dehydrogenase reductase Sdr
KQ253_17710	COG0583	DNA-binding transcription factor activity
KQ253_17725	COG0318	PFAM AMP-dependent synthetase and ligase
KQ253_17730	COG1530	ribonuclease E activity
KQ253_17740	COG0546	phosphoglycolate phosphatase activity
KQ253_17745	COG2378	regulation of single-species biofilm formation
KQ253_17750	COG0625	glutathione transferase activity
KQ253_17760	COG0583	DNA-binding transcription factor activity
KQ253_17825	COG0473	3-isopropylmalate dehydrogenase activity
KQ253_17885	COG2826	transposase and inactivated derivatives, IS30 family
KQ253_17900	COG1560	Kdo2-lipid A biosynthetic process
KQ253_17905	COG1280	lysine exporter protein (LysE YggA)
KQ253_17910	COG0488	(ABC) transporter
KQ253_17915	COG2900	Belongs to the SlyX family
KQ253_17925	COG1733	regulation of RNA biosynthetic process
KQ253_17950	COG0210	DNA helicase
KQ253_17955	COG0724	RNA recognition motif
KQ253_17975	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KQ253_17975	COG4651	solute:proton antiporter activity
KQ253_18000	COG0788	formyltetrahydrofolate deformylase activity
KQ253_18100	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KQ253_18100	COG2813	Specifically methylates the guanine in position
KQ253_18110	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KQ253_18120	COG4774	siderophore transport
KQ253_18130	COG0740	serine-type endopeptidase activity
KQ253_18150	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KQ253_18150	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KQ253_18155	COG0280	phosphate acetyltransferase
KQ253_18155	COG0857	belongs to the CobB CobQ family
KQ253_18160	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KQ253_18170	COG0800	Aldolase
KQ253_18180	COG3265	gluconokinase activity
KQ253_18185	COG1012	belongs to the aldehyde dehydrogenase family
KQ253_18195	COG2267	carboxylic ester hydrolase activity
KQ253_18210	COG0793	Belongs to the peptidase S41A family
KQ253_18245	COG1426	Protein conserved in bacteria
KQ253_18285	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KQ253_18295	COG1162	GTPase activity
KQ253_18300	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KQ253_18315	COG1538	Outer membrane efflux protein
KQ253_18320	COG0577	efflux transmembrane transporter activity
KQ253_18320	COG1136	(ABC) transporter
KQ253_18325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KQ253_18350	COG0028	Belongs to the TPP enzyme family
KQ253_18355	COG0440	acetolactate synthase activity
KQ253_18390	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KQ253_18405	COG0084	hydrolase, TatD family'
KQ253_18420	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KQ253_18430	COG0583	DNA-binding transcription factor activity
KQ253_18440	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KQ253_18445	COG2814	Major facilitator Superfamily
KQ253_18455	COG0697	spore germination
KQ253_18485	COG3622	Belongs to the hyi family
KQ253_18490	COG2084	Dehydrogenase
KQ253_18495	COG1024	Enoyl-CoA hydratase
KQ253_18500	COG0784	Response regulator, receiver
KQ253_18500	COG2205	protein histidine kinase activity
KQ253_18500	COG5002	protein histidine kinase activity
KQ253_18520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KQ253_18530	COG3956	TIGRFAM MazG family protein
KQ253_18535	COG1555	photosystem II stabilization
KQ253_18540	COG0617	tRNA 3'-terminal CCA addition
KQ253_18545	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KQ253_18565	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KQ253_18570	COG3028	Belongs to the UPF0307 family
KQ253_18575	COG0318	PFAM AMP-dependent synthetase and ligase
KQ253_18590	COG0625	glutathione transferase activity
KQ253_18595	COG1238	metal cluster binding
KQ253_18630	COG0072	phenylalanine-tRNA ligase activity
KQ253_18660	COG0248	Ppx GppA phosphatase
KQ253_18670	COG0037	tRNA processing
KQ253_18710	COG1764	response to oxidative stress
KQ253_18715	COG1846	Transcriptional regulator
KQ253_18725	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KQ253_18785	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KQ253_18790	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KQ253_18795	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KQ253_18855	COG1214	PFAM Peptidase M22, glycoprotease
KQ253_18870	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
KQ253_18880	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KQ253_18885	COG0561	phosphatase activity
KQ253_18895	COG2132	Multicopper oxidase
KQ253_18915	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KQ253_18920	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KQ253_18925	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KQ253_18955	COG1063	alcohol dehydrogenase
KQ253_18960	COG0583	DNA-binding transcription factor activity
KQ253_18965	COG1960	acyl-CoA dehydrogenase activity
KQ253_18970	COG2814	Major facilitator Superfamily
KQ253_18975	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KQ253_18990	COG0583	DNA-binding transcription factor activity
KQ253_19005	COG0583	DNA-binding transcription factor activity
KQ253_19035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KQ253_19090	COG0384	phenazine biosynthesis protein PhzF
KQ253_19100	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KQ253_19120	COG0745	RESPONSE REGULATOR receiver
KQ253_19160	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KQ253_19190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KQ253_19195	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KQ253_19215	COG0583	DNA-binding transcription factor activity
KQ253_19235	COG0668	transmembrane transport
KQ253_19245	COG2081	HI0933 family
KQ253_19250	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KQ253_19280	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KQ253_19280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KQ253_19290	COG0489	protein tyrosine kinase activity
KQ253_19340	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KQ253_19350	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KQ253_19365	COG0730	response to heat
KQ253_19375	COG1196	nuclear chromosome segregation
KQ253_19395	COG2223	nitrite transmembrane transporter activity
KQ253_19400	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
KQ253_19405	COG1877	trehalose-phosphatase activity
KQ253_19410	COG2826	transposase and inactivated derivatives, IS30 family
KQ253_19415	COG2226	methyltransferase
KQ253_19415	COG0596	Alpha beta hydrolase
KQ253_19415	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KQ253_19430	COG4106	trans-aconitate 2-methyltransferase activity
KQ253_19445	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KQ253_19450	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KQ253_19455	COG0009	L-threonylcarbamoyladenylate synthase
KQ253_19460	COG3101	peptidyl-lysine hydroxylation
KQ253_19465	COG1399	metal-binding, possibly nucleic acid-binding protein
KQ253_19490	COG1652	LysM domain
KQ253_19495	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KQ253_19495	COG0352	thiamine-phosphate diphosphorylase activity
KQ253_19495	COG0351	phosphomethylpyrimidine kinase
KQ253_19505	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KQ253_19535	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KQ253_19565	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KQ253_19580	COG0358	DNA primase activity
KQ253_19590	COG0564	pseudouridine synthase activity
KQ253_19940	COG0739	heme binding
KQ253_19985	COG0582	viral genome integration into host DNA
KQ253_19995	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KQ253_20015	COG0583	DNA-binding transcription factor activity
KQ253_20020	COG0473	3-isopropylmalate dehydrogenase activity
KQ253_20030	COG0657	acetylesterase activity
KQ253_20040	COG1012	belongs to the aldehyde dehydrogenase family
KQ253_20060	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KQ253_20060	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KQ253_20075	COG1981	membrane
KQ253_20120	COG0456	acetyltransferase
KQ253_20130	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KQ253_20135	COG0492	ferredoxin-NADP+ reductase activity
KQ253_20140	COG1674	ftsk spoiiie
KQ253_20145	COG1280	lysine exporter protein (LysE YggA)
KQ253_20160	COG2894	cell division
KQ253_20175	COG0204	Acyl-transferase
KQ253_20180	COG2885	chlorophyll binding
KQ253_20185	COG0210	DNA helicase
KQ253_20195	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KQ253_20210	COG0121	glutamine amidotransferase
KQ253_20230	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KQ253_20235	COG0735	belongs to the Fur family
KQ253_20260	COG0420	3'-5' exonuclease activity
KQ253_20280	COG1090	epimerase
KQ253_20295	COG2050	protein possibly involved in aromatic compounds catabolism
KQ253_20305	COG2814	Major facilitator Superfamily
KQ253_20310	COG0405	Gamma-glutamyltransferase
KQ253_20380	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KQ253_20475	COG1484	DNA-dependent DNA replication