locus-tag	class	description
HBM82_00010	COG0592	DNA-directed DNA polymerase activity
HBM82_00020	COG0187	DNA topoisomerase II activity
HBM82_00030	COG0586	Pfam SNARE associated Golgi protein
HBM82_00035	COG0488	(ABC) transporter
HBM82_00060	COG0596	Alpha beta hydrolase
HBM82_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HBM82_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HBM82_00110	COG0733	neurotransmitter:sodium symporter activity
HBM82_00150	COG2233	PERMEase
HBM82_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBM82_00200	COG2814	Major facilitator Superfamily
HBM82_00205	COG0656	L-ascorbic acid biosynthetic process
HBM82_00210	COG0583	DNA-binding transcription factor activity
HBM82_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBM82_00230	COG1064	alcohol dehydrogenase
HBM82_00235	COG2818	Glycosylase
HBM82_00250	COG1194	a g-specific adenine glycosylase
HBM82_00270	COG2983	Belongs to the UPF0260 family
HBM82_00275	COG2133	pyrroloquinoline quinone binding
HBM82_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HBM82_00285	COG2116	formate transmembrane transporter activity
HBM82_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBM82_00310	COG1335	isochorismatase
HBM82_00315	COG0385	Bile acid
HBM82_00320	COG0534	Mate efflux family protein
HBM82_00325	COG1683	Conserved Protein
HBM82_00345	COG0625	glutathione transferase activity
HBM82_00355	COG1113	amino acid transport
HBM82_00365	COG0523	cobalamin synthesis protein
HBM82_00375	COG2188	Transcriptional regulator
HBM82_00405	COG0010	Belongs to the arginase family
HBM82_00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HBM82_00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HBM82_00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HBM82_00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HBM82_00540	COG0534	Mate efflux family protein
HBM82_00545	COG0436	Aminotransferase
HBM82_00550	COG2733	membrane
HBM82_00565	COG2918	glutathione biosynthetic process
HBM82_00575	COG3501	Rhs element vgr protein
HBM82_00580	COG1388	LysM domain
HBM82_00580	COG0791	NLP P60 protein
HBM82_00595	COG3150	esterase
HBM82_00605	COG1028	Short-chain dehydrogenase reductase Sdr
HBM82_00610	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
HBM82_00620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HBM82_00630	COG2233	PERMEase
HBM82_00635	COG2351	hydroxyisourate hydrolase activity
HBM82_00670	COG3706	GGDEF domain
HBM82_00685	COG1393	Belongs to the ArsC family
HBM82_00690	COG0708	Exodeoxyribonuclease III
HBM82_00710	COG0189	ligase activity
HBM82_00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HBM82_00740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HBM82_00755	COG4942	peptidase
HBM82_00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
HBM82_00775	COG2119	membrane
HBM82_00780	COG4774	siderophore transport
HBM82_00785	COG0426	domain, Protein
HBM82_00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBM82_00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HBM82_00830	COG1902	pentaerythritol trinitrate reductase activity
HBM82_00835	COG1519	Transferase
HBM82_00840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HBM82_00845	COG0668	transmembrane transport
HBM82_00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HBM82_00860	COG1335	isochorismatase
HBM82_00865	COG1522	sequence-specific DNA binding
HBM82_00870	COG3328	transposase activity
HBM82_00895	COG0784	Response regulator, receiver
HBM82_00895	COG2205	protein histidine kinase activity
HBM82_00895	COG2198	Histidine kinase
HBM82_00900	COG3162	membrane
HBM82_00905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBM82_00915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBM82_00925	COG3706	GGDEF domain
HBM82_00935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HBM82_00940	COG1309	transcriptional regulator
HBM82_00960	COG0352	thiamine-phosphate diphosphorylase activity
HBM82_00960	COG0351	phosphomethylpyrimidine kinase
HBM82_00960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HBM82_00970	COG2814	Major facilitator Superfamily
HBM82_00985	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HBM82_00995	COG1113	amino acid transport
HBM82_01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HBM82_01010	COG1012	belongs to the aldehyde dehydrogenase family
HBM82_01020	COG1335	isochorismatase
HBM82_01050	COG2814	Major facilitator Superfamily
HBM82_01055	COG0583	DNA-binding transcription factor activity
HBM82_01075	COG0667	Aldo Keto reductase
HBM82_01105	COG1733	regulation of RNA biosynthetic process
HBM82_01110	COG2249	NAD(P)H dehydrogenase (quinone) activity
HBM82_01175	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HBM82_01190	COG2329	Antibiotic biosynthesis monooxygenase
HBM82_01220	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HBM82_01250	COG0427	acetyl-CoA hydrolase
HBM82_01265	COG0745	RESPONSE REGULATOR receiver
HBM82_01275	COG0659	secondary active sulfate transmembrane transporter activity
HBM82_01280	COG4221	oxidoreductase activity
HBM82_01285	COG2873	o-acetylhomoserine
HBM82_01290	COG0488	(ABC) transporter
HBM82_01375	COG0833	amino acid
HBM82_01420	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HBM82_01425	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HBM82_01440	COG2226	methyltransferase
HBM82_01490	COG0067	glutamate synthase
HBM82_01490	COG0069	glutamate synthase activity
HBM82_01490	COG0070	glutamate synthase
HBM82_01495	COG0493	'glutamate synthase
HBM82_01505	COG1704	LemA family
HBM82_01510	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HBM82_01530	COG1061	Type III restriction enzyme res subunit
HBM82_01560	COG3307	-O-antigen
HBM82_01580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HBM82_01595	COG0194	GDP metabolic process
HBM82_01645	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HBM82_01665	COG5380	lipid catabolic process
HBM82_01670	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HBM82_01695	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HBM82_01700	COG0277	FAD linked oxidase domain protein
HBM82_01710	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HBM82_01715	COG2249	NAD(P)H dehydrogenase (quinone) activity
HBM82_01730	COG1289	transmembrane transporter activity
HBM82_01740	COG0628	permease
HBM82_01745	COG1192	Involved in chromosome partitioning
HBM82_01775	COG0833	amino acid
HBM82_01780	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HBM82_01785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HBM82_01795	COG1012	belongs to the aldehyde dehydrogenase family
HBM82_01835	COG0583	DNA-binding transcription factor activity
HBM82_01880	COG0517	IMP dehydrogenase activity
HBM82_01885	COG1983	PspC domain protein
HBM82_01895	COG1960	acyl-CoA dehydrogenase activity
HBM82_01910	COG0408	coproporphyrinogen oxidase activity
HBM82_01930	COG0513	Belongs to the DEAD box helicase family
HBM82_01940	COG1127	ABC transporter
HBM82_01945	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HBM82_01955	COG2854	intermembrane phospholipid transfer
HBM82_01965	COG0598	Magnesium transport protein CorA
HBM82_01975	COG0494	nUDIX hydrolase
HBM82_01980	COG1040	competence protein
HBM82_01985	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HBM82_02005	COG1946	Acyl-CoA thioesterase
HBM82_02010	COG1301	dicarboxylic acid transport
HBM82_02025	COG1959	2 iron, 2 sulfur cluster binding
HBM82_02030	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HBM82_02030	COG1017	nitric oxide dioxygenase activity
HBM82_02035	COG0433	COG0433 Predicted ATPase
HBM82_02040	COG0626	cystathionine gamma-synthase activity
HBM82_02195	COG1960	acyl-CoA dehydrogenase activity
HBM82_02200	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HBM82_02230	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HBM82_02235	COG0339	signal peptide processing
HBM82_02240	COG0557	exoribonuclease II activity
HBM82_02285	COG0179	Fumarylacetoacetate (FAA) hydrolase
HBM82_02290	COG2169	Transcriptional regulator
HBM82_02295	COG0697	spore germination
HBM82_02300	COG1295	ribonuclease BN
HBM82_02335	COG1702	phosphate starvation-inducible protein PhoH
HBM82_02345	COG0741	lytic transglycosylase activity
HBM82_02345	COG0739	heme binding
HBM82_02345	COG1196	nuclear chromosome segregation
HBM82_02375	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HBM82_02380	COG1183	phosphatidylcholine synthase activity
HBM82_02425	COG1960	acyl-CoA dehydrogenase activity
HBM82_02430	COG1309	transcriptional regulator
HBM82_02445	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HBM82_02450	COG1960	acyl-CoA dehydrogenase activity
HBM82_02470	COG2969	positive regulation of protein catabolic process
HBM82_02480	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HBM82_02495	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HBM82_02500	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HBM82_02520	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HBM82_02530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBM82_02535	COG1408	metallophosphoesterase
HBM82_02545	COG2199	diguanylate cyclase activity
HBM82_02605	COG1607	acyl-coa hydrolase
HBM82_02635	COG2350	Protein conserved in bacteria
HBM82_02645	COG0613	PHP domain protein
HBM82_02650	COG3781	membrane
HBM82_02660	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HBM82_02665	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HBM82_02675	COG1862	Preprotein translocase
HBM82_02705	COG2205	protein histidine kinase activity
HBM82_02710	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HBM82_02730	COG0726	polysaccharide deacetylase
HBM82_02735	COG0463	Glycosyl transferase, family 2
HBM82_02740	COG0438	transferase activity, transferring glycosyl groups
HBM82_02805	COG0625	glutathione transferase activity
HBM82_02810	COG0583	DNA-binding transcription factor activity
HBM82_02815	COG1960	acyl-CoA dehydrogenase activity
HBM82_02820	COG1960	acyl-CoA dehydrogenase activity
HBM82_02830	COG2205	protein histidine kinase activity
HBM82_02835	COG0745	RESPONSE REGULATOR receiver
HBM82_02840	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HBM82_02860	COG2096	Adenosyltransferase
HBM82_02910	COG0285	dihydrofolate synthase activity
HBM82_02930	COG0450	alkyl hydroperoxide reductase
HBM82_02945	COG0477	Major facilitator Superfamily
HBM82_02950	COG1272	protein, Hemolysin III
HBM82_02985	COG0183	Belongs to the thiolase family
HBM82_02990	COG2207	Transcriptional regulator
HBM82_03010	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBM82_03030	COG0183	Belongs to the thiolase family
HBM82_03040	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HBM82_03040	COG2885	chlorophyll binding
HBM82_03050	COG1690	Belongs to the RtcB family
HBM82_03055	COG0833	amino acid
HBM82_03065	COG2233	PERMEase
HBM82_03095	COG2094	Belongs to the DNA glycosylase MPG family
HBM82_03100	COG4772	TonB-dependent receptor
HBM82_03115	COG1902	pentaerythritol trinitrate reductase activity
HBM82_03120	COG0679	Auxin Efflux Carrier
HBM82_03130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HBM82_03135	COG0354	folic acid binding
HBM82_03145	COG3189	MarR family transcriptional regulator
HBM82_03150	COG2824	Alkylphosphonate utilization operon protein PhnA
HBM82_03155	COG3422	double-strand break repair
HBM82_03195	COG0840	transmembrane signaling receptor activity
HBM82_03215	COG5510	response to toxic substance
HBM82_03225	COG2832	Protein of unknown function (DUF454)
HBM82_03230	COG1376	ErfK ybiS ycfS ynhG family protein
HBM82_03270	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HBM82_03280	COG1289	transmembrane transporter activity
HBM82_03285	COG2814	Major facilitator Superfamily
HBM82_03305	COG1115	amino acid carrier protein
HBM82_03310	COG1752	Esterase of the alpha-beta hydrolase superfamily
HBM82_03315	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HBM82_03320	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HBM82_03360	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HBM82_03370	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HBM82_03375	COG1077	Cell shape determining protein MreB Mrl
HBM82_03380	COG1792	Involved in formation and maintenance of cell shape
HBM82_03385	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HBM82_03390	COG0424	maF-like protein
HBM82_03395	COG1530	ribonuclease E activity
HBM82_03405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBM82_03415	COG0560	Phosphoserine phosphatase
HBM82_03425	COG2249	NAD(P)H dehydrogenase (quinone) activity
HBM82_03450	COG2207	Transcriptional regulator
HBM82_03470	COG1113	amino acid transport
HBM82_03475	COG2828	Protein conserved in bacteria
HBM82_03480	COG0142	geranyltranstransferase activity
HBM82_03485	COG2315	Protein conserved in bacteria
HBM82_03500	COG1752	Esterase of the alpha-beta hydrolase superfamily
HBM82_03520	COG2194	sulfuric ester hydrolase activity
HBM82_03525	COG0745	RESPONSE REGULATOR receiver
HBM82_03530	COG0642	Histidine kinase
HBM82_03540	COG0004	ammonium transporteR
HBM82_03545	COG0583	DNA-binding transcription factor activity
HBM82_03565	COG0525	valine-tRNA ligase activity
HBM82_03575	COG1028	Short-chain dehydrogenase reductase Sdr
HBM82_03585	COG0393	Putative heavy-metal-binding
HBM82_03590	COG0393	Putative heavy-metal-binding
HBM82_03595	COG1538	Outer membrane efflux protein
HBM82_03605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBM82_03610	COG0671	phosphoesterase, PA-phosphatase related
HBM82_03640	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HBM82_03655	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HBM82_03655	COG1648	precorrin-2 dehydrogenase activity
HBM82_03660	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HBM82_03665	COG1733	regulation of RNA biosynthetic process
HBM82_03675	COG0531	amino acid
HBM82_03690	COG0321	lipoyl(octanoyl) transferase activity
HBM82_03695	COG2921	Belongs to the UPF0250 family
HBM82_03735	COG2009	succinate dehydrogenase
HBM82_03740	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HBM82_03745	COG1053	succinate dehydrogenase
HBM82_03750	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HBM82_03775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HBM82_03795	COG2354	Protein conserved in bacteria
HBM82_03800	COG2321	neutral zinc metallopeptidase
HBM82_03850	COG2843	Capsule synthesis protein
HBM82_03865	COG0589	response to stress
HBM82_03885	COG0505	Belongs to the CarA family
HBM82_03910	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HBM82_03915	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HBM82_03965	COG0477	Major facilitator Superfamily
HBM82_03970	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HBM82_03985	COG1597	lipid kinase activity
HBM82_03990	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HBM82_04020	COG0584	glycerophosphoryl diester phosphodiesterase
HBM82_04040	COG0741	lytic transglycosylase activity
HBM82_04060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HBM82_04075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBM82_04100	COG0778	Nitroreductase
HBM82_04115	COG1929	Belongs to the glycerate kinase type-1 family
HBM82_04120	COG0243	molybdopterin cofactor binding
HBM82_04125	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HBM82_04130	COG3339	Conserved Protein
HBM82_04140	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
HBM82_04155	COG1113	amino acid transport
HBM82_04165	COG0019	diaminopimelate decarboxylase activity
HBM82_04175	COG1280	lysine exporter protein (LysE YggA)
HBM82_04180	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HBM82_04210	COG0463	Glycosyl transferase, family 2
HBM82_04230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBM82_04265	COG4591	ABC-type transport system involved in lipoprotein release permease component
HBM82_04270	COG1136	(ABC) transporter
HBM82_04275	COG0658	competence protein
HBM82_04275	COG2333	competence protein COMEC
HBM82_04285	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HBM82_04285	COG0616	signal peptide processing
HBM82_04290	COG0596	Alpha beta hydrolase
HBM82_04295	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HBM82_04305	COG0628	permease
HBM82_04340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HBM82_04360	COG0823	Involved in the tonB-independent uptake of proteins
HBM82_04380	COG0824	Thioesterase
HBM82_04385	COG1473	amidohydrolase
HBM82_04405	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HBM82_04405	COG0047	phosphoribosylformylglycinamidine synthase activity
HBM82_04410	COG2814	Major facilitator Superfamily
HBM82_04420	COG1024	Enoyl-CoA hydratase
HBM82_04425	COG1051	belongs to the nudix hydrolase family
HBM82_04425	COG1056	cytidyltransferase-related domain
HBM82_04435	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HBM82_04450	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HBM82_04465	COG4625	pathogenesis
HBM82_04470	COG0583	DNA-binding transcription factor activity
HBM82_04475	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HBM82_04480	COG4208	sulfate ABC transporter
HBM82_04485	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HBM82_04495	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HBM82_04500	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HBM82_04505	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HBM82_04525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HBM82_04540	COG0681	Belongs to the peptidase S26 family
HBM82_04555	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HBM82_04565	COG1381	Involved in DNA repair and RecF pathway recombination
HBM82_04570	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HBM82_04580	COG4221	oxidoreductase activity
HBM82_04610	COG0436	Aminotransferase
HBM82_04630	COG0556	nucleotide-excision repair
HBM82_04830	COG5410	chromosome segregation
HBM82_04920	COG1598	PFAM Uncharacterised protein family UPF0150
HBM82_04990	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HBM82_05010	COG2070	2-Nitropropane dioxygenase
HBM82_05040	COG1215	transferase activity, transferring glycosyl groups
HBM82_05055	COG0415	Belongs to the DNA photolyase family
HBM82_05065	COG1252	NADH dehydrogenase
HBM82_05070	COG1686	Belongs to the peptidase S11 family
HBM82_05085	COG1187	pseudouridine synthase activity
HBM82_05275	COG5410	chromosome segregation
HBM82_05390	COG3561	AntA/AntB antirepressor
HBM82_05420	COG0739	heme binding
HBM82_05490	COG0582	viral genome integration into host DNA
HBM82_05515	COG0477	Major facilitator Superfamily
HBM82_05520	COG0583	DNA-binding transcription factor activity
HBM82_05535	COG0612	Peptidase, M16
HBM82_05560	COG0352	thiamine-phosphate diphosphorylase activity
HBM82_05595	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HBM82_05610	COG1309	transcriptional regulator
HBM82_05620	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HBM82_05625	COG0076	glutamate decarboxylase activity
HBM82_05635	COG1522	sequence-specific DNA binding
HBM82_05640	COG3961	Belongs to the TPP enzyme family
HBM82_05645	COG1113	amino acid transport
HBM82_05650	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HBM82_05655	COG0573	inorganic phosphate transmembrane transporter activity
HBM82_05665	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HBM82_05670	COG0616	signal peptide processing
HBM82_05680	COG3328	transposase activity
HBM82_05710	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HBM82_05715	COG1686	Belongs to the peptidase S11 family
HBM82_05740	COG0583	DNA-binding transcription factor activity
HBM82_05745	COG1067	ATP-dependent peptidase activity
HBM82_05790	COG1966	Carbon starvation protein
HBM82_05795	COG2879	small protein
HBM82_05830	COG2508	Transcriptional regulator
HBM82_05830	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HBM82_05850	COG1113	amino acid transport
HBM82_05855	COG0583	DNA-binding transcription factor activity
HBM82_05860	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBM82_05865	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBM82_05875	COG1012	belongs to the aldehyde dehydrogenase family
HBM82_05880	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBM82_05885	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HBM82_05885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HBM82_05920	COG2814	Major facilitator Superfamily
HBM82_05925	COG4948	Mandelate Racemase Muconate Lactonizing
HBM82_05935	COG1309	transcriptional regulator
HBM82_05955	COG1741	Belongs to the pirin family
HBM82_05965	COG2964	Protein conserved in bacteria
HBM82_05980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBM82_05985	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBM82_05990	COG4605	iron ion homeostasis
HBM82_05995	COG4604	ABC transporter, ATP-binding protein
HBM82_06000	COG4607	ABC-type enterochelin transport system periplasmic component
HBM82_06005	COG4774	siderophore transport
HBM82_06015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBM82_06020	COG1021	2,3-dihydroxybenzoate-AMP ligase
HBM82_06025	COG3433	isochorismatase activity
HBM82_06025	COG1535	isochorismatase
HBM82_06040	COG1132	(ABC) transporter
HBM82_06050	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HBM82_06060	COG1169	isochorismate synthase
HBM82_06075	COG3739	integral membrane protein
HBM82_06110	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HBM82_06140	COG0308	aminopeptidase N
HBM82_06145	COG0512	Glutamine amidotransferase of anthranilate synthase
HBM82_06155	COG3104	oligopeptide transport
HBM82_06160	COG0174	glutamine synthetase
HBM82_06170	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HBM82_06205	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HBM82_06210	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HBM82_06215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HBM82_06235	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HBM82_06240	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HBM82_06245	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HBM82_06260	COG1960	acyl-CoA dehydrogenase activity
HBM82_06265	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HBM82_06270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HBM82_06280	COG2223	nitrite transmembrane transporter activity
HBM82_06290	COG0024	Methionine aminopeptidase
HBM82_06295	COG0052	Belongs to the universal ribosomal protein uS2 family
HBM82_06310	COG2207	Transcriptional regulator
HBM82_06335	COG2951	lytic endotransglycosylase activity
HBM82_06340	COG0772	Belongs to the SEDS family
HBM82_06355	COG0842	Transport permease protein
HBM82_06360	COG1131	(ABC) transporter
HBM82_06405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBM82_06420	COG4215	(ABC) transporter
HBM82_06425	COG4160	amino acid transport
HBM82_06430	COG4598	ABC transporter
HBM82_06440	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HBM82_06450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBM82_06465	COG1720	tRNA m6t6A37 methyltransferase activity
HBM82_06485	COG0745	RESPONSE REGULATOR receiver
HBM82_06490	COG0642	Histidine kinase
HBM82_06500	COG0494	nUDIX hydrolase
HBM82_06510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HBM82_06515	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HBM82_06520	COG3139	Protein of unknown function (DUF1315)
HBM82_06525	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HBM82_06530	COG1301	dicarboxylic acid transport
HBM82_06535	COG1960	acyl-CoA dehydrogenase activity
HBM82_06540	COG2819	hydrolase of the alpha beta superfamily
HBM82_06550	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HBM82_06560	COG2195	Cleaves the N-terminal amino acid of tripeptides
HBM82_06565	COG1234	tRNA 3'-trailer cleavage
HBM82_06595	COG2363	Small membrane protein
HBM82_06615	COG0513	Belongs to the DEAD box helicase family
HBM82_06625	COG0778	Nitroreductase
HBM82_06655	COG1286	toxin biosynthetic process
HBM82_06680	COG4783	chaperone-mediated protein folding
HBM82_06685	COG1610	YqeY-like protein
HBM82_06785	COG3111	PFAM Bacterial OB fold (BOF) protein
HBM82_06810	COG3243	poly(R)-hydroxyalkanoic acid synthase
HBM82_06815	COG0786	glutamate:sodium symporter activity
HBM82_06825	COG2186	Transcriptional regulator
HBM82_06875	COG0477	Major facilitator Superfamily
HBM82_06900	COG2985	domain, Protein
HBM82_06910	COG2995	paraquat-inducible protein a
HBM82_06915	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HBM82_06915	COG3008	intermembrane lipid transfer
HBM82_06935	COG0482	sulfurtransferase activity
HBM82_06955	COG3173	Aminoglycoside phosphotransferase
HBM82_06965	COG2433	Pfam Transposase IS66
HBM82_07010	COG1301	dicarboxylic acid transport
HBM82_07020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBM82_07025	COG2011	ABC-type metal ion transport system permease component
HBM82_07030	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HBM82_07035	COG1464	Belongs to the NlpA lipoprotein family
HBM82_07040	COG0151	Belongs to the GarS family
HBM82_07045	COG0138	bifunctional purine biosynthesis protein purh
HBM82_07050	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HBM82_07080	COG2308	Evidence 4 Homologs of previously reported genes of
HBM82_07090	COG1305	Transglutaminase-like
HBM82_07100	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HBM82_07105	COG0305	Participates in initiation and elongation during chromosome replication
HBM82_07130	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HBM82_07140	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HBM82_07145	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HBM82_07170	COG1649	PFAM Uncharacterised BCR, COG1649
HBM82_07170	COG0726	polysaccharide deacetylase
HBM82_07175	COG1215	transferase activity, transferring glycosyl groups
HBM82_07180	COG3658	cytochrome
HBM82_07190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBM82_07205	COG0583	DNA-binding transcription factor activity
HBM82_07225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBM82_07230	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBM82_07245	COG1960	acyl-CoA dehydrogenase activity
HBM82_07250	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HBM82_07255	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBM82_07280	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HBM82_07285	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HBM82_07295	COG2205	protein histidine kinase activity
HBM82_07300	COG0745	RESPONSE REGULATOR receiver
HBM82_07305	COG0174	glutamine synthetase
HBM82_07325	COG0729	surface antigen
HBM82_07350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HBM82_07355	COG2814	Major facilitator Superfamily
HBM82_07370	COG0583	DNA-binding transcription factor activity
HBM82_07385	COG1187	pseudouridine synthase activity
HBM82_07405	COG0802	atpase or kinase
HBM82_07410	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HBM82_07420	COG1923	regulation of RNA biosynthetic process
HBM82_07425	COG0697	spore germination
HBM82_07440	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HBM82_07450	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HBM82_07455	COG0519	Catalyzes the synthesis of GMP from XMP
HBM82_07455	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HBM82_07460	COG4302	ethanolamine ammonia-lyase activity
HBM82_07465	COG4303	Ethanolamine ammonia lyase large subunit
HBM82_07470	COG0531	amino acid
HBM82_07490	COG1454	alcohol dehydrogenase
HBM82_07495	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HBM82_07505	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HBM82_07525	COG0308	aminopeptidase N
HBM82_07555	COG1605	Chorismate mutase
HBM82_07570	COG1309	transcriptional regulator
HBM82_07580	COG0668	transmembrane transport
HBM82_07620	COG4773	Receptor
HBM82_07640	COG0488	(ABC) transporter
HBM82_07645	COG0589	response to stress
HBM82_07670	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HBM82_07680	COG3135	benzoate transporter
HBM82_07685	COG1522	sequence-specific DNA binding
HBM82_07695	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HBM82_07700	COG0583	DNA-binding transcription factor activity
HBM82_07710	COG0183	Belongs to the thiolase family
HBM82_07720	COG2030	dehydratase
HBM82_07740	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HBM82_07750	COG0824	Thioesterase
HBM82_07755	COG1454	alcohol dehydrogenase
HBM82_07765	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HBM82_07785	COG0069	glutamate synthase activity
HBM82_07805	COG2814	Major facilitator Superfamily
HBM82_07820	COG0511	ligase activity, forming carbon-carbon bonds
HBM82_07840	COG1116	anion transmembrane transporter activity
HBM82_07840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBM82_07845	COG0745	RESPONSE REGULATOR receiver
HBM82_07855	COG2146	nitrite reductase [NAD(P)H] activity
HBM82_07855	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBM82_07860	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBM82_07865	COG0243	molybdopterin cofactor binding
HBM82_07875	COG0243	molybdopterin cofactor binding
HBM82_07880	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HBM82_07895	COG0521	Mo-molybdopterin cofactor biosynthetic process
HBM82_07895	COG0315	cyclic pyranopterin monophosphate synthase activity
HBM82_07900	COG0303	'Molybdopterin
HBM82_07910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBM82_07915	COG0697	spore germination
HBM82_07935	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HBM82_07940	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HBM82_07995	COG2204	response regulator
HBM82_08000	COG3852	Histidine kinase
HBM82_08020	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HBM82_08025	COG0575	Belongs to the CDS family
HBM82_08060	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HBM82_08075	COG2137	regulation of response to DNA damage stimulus
HBM82_08085	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HBM82_08090	COG1011	Hydrolase
HBM82_08115	COG1522	sequence-specific DNA binding
HBM82_08125	COG1113	amino acid transport
HBM82_08140	COG0659	secondary active sulfate transmembrane transporter activity
HBM82_08145	COG2135	peptidase activity
HBM82_08160	COG5001	Diguanylate cyclase
HBM82_08160	COG3300	MHYT domain
HBM82_08180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HBM82_08180	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HBM82_08180	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HBM82_08185	COG1105	Belongs to the carbohydrate kinase PfkB family
HBM82_08190	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBM82_08190	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HBM82_08220	COG0024	Methionine aminopeptidase
HBM82_08225	COG0583	DNA-binding transcription factor activity
HBM82_08235	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HBM82_08240	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HBM82_08245	COG0516	GMP reductase activity
HBM82_08245	COG0517	IMP dehydrogenase activity
HBM82_08270	COG0552	protein localization to endoplasmic reticulum
HBM82_08280	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HBM82_08295	COG4890	Cyd operon protein YbgT
HBM82_08300	COG1294	oxidase, subunit
HBM82_08315	COG1585	Membrane protein implicated in regulation of membrane protease activity
HBM82_08325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HBM82_08330	COG4774	siderophore transport
HBM82_08345	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HBM82_08350	COG0569	domain protein
HBM82_08355	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HBM82_08385	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HBM82_08390	COG0542	response to heat
HBM82_08415	COG0446	pyridine nucleotide-disulphide oxidoreductase
HBM82_08415	COG1902	pentaerythritol trinitrate reductase activity
HBM82_08460	COG2323	membrane
HBM82_08465	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HBM82_08475	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HBM82_08480	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HBM82_08485	COG0183	Belongs to the thiolase family
HBM82_08490	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HBM82_08495	COG0596	Alpha beta hydrolase
HBM82_08500	COG2271	Major facilitator Superfamily
HBM82_08505	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HBM82_08510	COG3485	protocatechuate 3,4-dioxygenase
HBM82_08515	COG3485	protocatechuate 3,4-dioxygenase
HBM82_08520	COG0710	3-dehydroquinate dehydratase activity
HBM82_08525	COG3420	alginic acid biosynthetic process
HBM82_08530	COG3659	wide pore channel activity
HBM82_08535	COG4993	Dehydrogenase
HBM82_08545	COG2391	methyltransferase activity
HBM82_08560	COG1414	Transcriptional regulator
HBM82_08565	COG0583	DNA-binding transcription factor activity
HBM82_08570	COG1960	acyl-CoA dehydrogenase activity
HBM82_08595	COG2814	Major facilitator Superfamily
HBM82_08605	COG0154	amidase activity
HBM82_08625	COG4638	Rieske (2fe-2S)
HBM82_08635	COG1028	Short-chain dehydrogenase reductase Sdr
HBM82_08645	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBM82_08655	COG3733	amine oxidase
HBM82_08665	COG1012	belongs to the aldehyde dehydrogenase family
HBM82_08675	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HBM82_08680	COG0183	Belongs to the thiolase family
HBM82_08685	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HBM82_08690	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HBM82_08700	COG4829	muconolactone delta-isomerase
HBM82_08705	COG4948	Mandelate Racemase Muconate Lactonizing
HBM82_08710	COG0583	DNA-binding transcription factor activity
HBM82_08720	COG2186	Transcriptional regulator
HBM82_08740	COG1012	belongs to the aldehyde dehydrogenase family
HBM82_08760	COG1960	acyl-CoA dehydrogenase activity
HBM82_08765	COG1028	Short-chain dehydrogenase reductase Sdr
HBM82_08770	COG3829	transcription factor binding
HBM82_08780	COG3162	membrane
HBM82_08795	COG1012	belongs to the aldehyde dehydrogenase family
HBM82_08810	COG0753	catalase activity
HBM82_08830	COG1846	Transcriptional regulator
HBM82_08835	COG0446	pyridine nucleotide-disulphide oxidoreductase
HBM82_08835	COG1902	pentaerythritol trinitrate reductase activity
HBM82_08845	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HBM82_08875	COG1309	transcriptional regulator
HBM82_08885	COG1335	isochorismatase
HBM82_08890	COG0583	DNA-binding transcription factor activity
HBM82_08900	COG0475	glutathione-regulated potassium exporter activity
HBM82_08900	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HBM82_08910	COG1473	amidohydrolase
HBM82_08920	COG2831	hemolysin activation secretion protein
HBM82_08925	COG3210	domain, Protein
HBM82_08955	COG2188	Transcriptional regulator
HBM82_08970	COG0583	DNA-binding transcription factor activity
HBM82_09000	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HBM82_09020	COG1566	PFAM secretion protein HlyD family protein
HBM82_09035	COG1012	belongs to the aldehyde dehydrogenase family
HBM82_09040	COG0129	dihydroxy-acid dehydratase activity
HBM82_09050	COG0583	DNA-binding transcription factor activity
HBM82_09055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HBM82_09065	COG2084	Dehydrogenase
HBM82_09070	COG2207	Transcriptional regulator
HBM82_09085	COG1064	alcohol dehydrogenase
HBM82_09100	COG1120	ATPase activity
HBM82_09120	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HBM82_09235	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HBM82_09285	COG1028	Short-chain dehydrogenase reductase Sdr
HBM82_09300	COG2207	Transcriptional regulator
HBM82_09310	COG2205	protein histidine kinase activity
HBM82_09315	COG0745	RESPONSE REGULATOR receiver
HBM82_09320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBM82_09325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HBM82_09330	COG1538	Outer membrane efflux protein
HBM82_09340	COG2072	flavoprotein involved in K transport
HBM82_09360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HBM82_09380	COG3539	Fimbrial protein
HBM82_09410	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HBM82_09420	COG0753	catalase activity
HBM82_09435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBM82_09500	COG1535	isochorismatase
HBM82_09500	COG3433	isochorismatase activity
HBM82_09505	COG1028	Short-chain dehydrogenase reductase Sdr
HBM82_09510	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HBM82_09515	COG4149	molybdate abc transporter
HBM82_09520	COG0725	ABC transporter, periplasmic molybdate-binding protein
HBM82_09530	COG4638	Rieske (2fe-2S)
HBM82_09535	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HBM82_09540	COG0543	2 iron, 2 sulfur cluster binding
HBM82_09540	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HBM82_09565	COG1028	Short-chain dehydrogenase reductase Sdr
HBM82_09580	COG2207	Transcriptional regulator
HBM82_09590	COG1028	Short-chain dehydrogenase reductase Sdr
HBM82_09595	COG2610	gluconate transmembrane transporter activity
HBM82_09605	COG0583	DNA-binding transcription factor activity
HBM82_09615	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HBM82_09620	COG2031	fatty acid transporter
HBM82_09625	COG0183	Belongs to the thiolase family
HBM82_09630	COG0583	DNA-binding transcription factor activity
HBM82_09635	COG0583	DNA-binding transcription factor activity
HBM82_09650	COG1027	Aspartate ammonia-lyase
HBM82_09660	COG0477	Major facilitator Superfamily
HBM82_09680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBM82_09685	COG4521	taurine ABC transporter
HBM82_09700	COG2188	Transcriptional regulator
HBM82_09710	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HBM82_09715	COG1733	regulation of RNA biosynthetic process
HBM82_09720	COG3708	Transcriptional regulator
HBM82_09720	COG2207	Transcriptional regulator
HBM82_09735	COG0730	response to heat
HBM82_09745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBM82_09745	COG3453	Protein conserved in bacteria
HBM82_09755	COG3781	membrane
HBM82_09760	COG1063	alcohol dehydrogenase
HBM82_09770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HBM82_09775	COG0508	dehydrogenase complex catalyzes the overall conversion of
HBM82_09780	COG0022	dehydrogenase e1 component
HBM82_09785	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HBM82_09790	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HBM82_09805	COG3706	GGDEF domain
HBM82_09820	COG0133	tryptophan synthase activity
HBM82_09830	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HBM82_09875	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HBM82_09900	COG2226	methyltransferase
HBM82_09955	COG0842	Transport permease protein
HBM82_09960	COG0842	Transport permease protein
HBM82_09965	COG1131	(ABC) transporter
HBM82_09980	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HBM82_09985	COG4773	Receptor
HBM82_10005	COG0730	response to heat
HBM82_10010	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HBM82_10030	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HBM82_10085	COG4264	IucA IucC family
HBM82_10090	COG4264	IucA IucC family
HBM82_10110	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HBM82_10125	COG1960	acyl-CoA dehydrogenase activity
HBM82_10130	COG1960	acyl-CoA dehydrogenase activity
HBM82_10135	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HBM82_10140	COG2207	Transcriptional regulator
HBM82_10145	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HBM82_10150	COG0776	regulation of translation
HBM82_10175	COG0822	iron-sulfur transferase activity
HBM82_10180	COG0316	Belongs to the HesB IscA family
HBM82_10210	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HBM82_10230	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HBM82_10235	COG0702	epimerase
HBM82_10270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBM82_10280	COG0339	signal peptide processing
HBM82_10330	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HBM82_10335	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HBM82_10365	COG0776	regulation of translation
HBM82_10430	COG0084	hydrolase, TatD family'
HBM82_10450	COG1663	tetraacyldisaccharide 4'-kinase activity
HBM82_10455	COG1132	(ABC) transporter
HBM82_10465	COG0811	peptide transport
HBM82_10470	COG1475	DNA binding
HBM82_10475	COG1192	Involved in chromosome partitioning
HBM82_10485	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HBM82_10500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HBM82_10505	COG0191	fructose-bisphosphate aldolase activity
HBM82_10525	COG0424	maF-like protein
HBM82_10530	COG2850	peptidyl-arginine hydroxylation
HBM82_10540	COG0640	Transcriptional regulator
HBM82_10555	COG3619	membrane
HBM82_10560	COG3122	Protein conserved in bacteria
HBM82_10565	COG1132	(ABC) transporter
HBM82_10585	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HBM82_10590	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBM82_10600	COG0506	proline dehydrogenase activity
HBM82_10600	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HBM82_10600	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HBM82_10605	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HBM82_10620	COG3698	Phosphodiester glycosidase
HBM82_10630	COG2353	YceI-like domain
HBM82_10640	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HBM82_10685	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HBM82_10685	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HBM82_10710	COG3539	Fimbrial protein
HBM82_10715	COG3121	Chaperone
HBM82_10740	COG0697	spore germination
HBM82_10750	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HBM82_10760	COG0583	DNA-binding transcription factor activity
HBM82_10780	COG1309	transcriptional regulator
HBM82_10795	COG1522	sequence-specific DNA binding
HBM82_10805	COG1126	abc transporter atp-binding protein
HBM82_10810	COG0765	amino acid transport
HBM82_10815	COG0765	amino acid transport
HBM82_10845	COG1464	Belongs to the NlpA lipoprotein family
HBM82_10855	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HBM82_10860	COG2011	ABC-type metal ion transport system permease component
HBM82_10865	COG0012	GTP binding
HBM82_10890	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HBM82_10930	COG0386	Belongs to the glutathione peroxidase family
HBM82_10940	COG0436	Aminotransferase
HBM82_10980	COG3634	alkyl hydroperoxide reductase activity
HBM82_10995	COG0583	DNA-binding transcription factor activity
HBM82_11000	COG0798	PFAM Bile acid sodium symporter
HBM82_11005	COG0640	Transcriptional regulator
HBM82_11020	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HBM82_11030	COG0583	DNA-binding transcription factor activity
HBM82_11040	COG1953	Uracil, thiamine, allantoin
HBM82_11050	COG2175	clavaminate synthase activity
HBM82_11055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBM82_11060	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HBM82_11065	COG4521	taurine ABC transporter
HBM82_11075	COG0477	Major facilitator Superfamily
HBM82_11095	COG1271	oxidase subunit
HBM82_11100	COG1294	oxidase, subunit
HBM82_11110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBM82_11130	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HBM82_11150	COG3052	prosthetic group binding
HBM82_11155	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
HBM82_11165	COG2814	Major facilitator Superfamily
HBM82_11185	COG1346	cytolysis
HBM82_11195	COG0583	DNA-binding transcription factor activity
HBM82_11200	COG0625	glutathione transferase activity
HBM82_11205	COG0625	glutathione transferase activity
HBM82_11210	COG0583	DNA-binding transcription factor activity
HBM82_11225	COG1045	serine acetyltransferase
HBM82_11230	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HBM82_11235	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HBM82_11245	COG1280	lysine exporter protein (LysE YggA)
HBM82_11260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBM82_11265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBM82_11270	COG1126	abc transporter atp-binding protein
HBM82_11275	COG0765	amino acid transport
HBM82_11280	COG0765	amino acid transport
HBM82_11300	COG2205	protein histidine kinase activity
HBM82_11300	COG0784	Response regulator, receiver
HBM82_11320	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HBM82_11340	COG1028	Short-chain dehydrogenase reductase Sdr
HBM82_11395	COG0583	DNA-binding transcription factor activity
HBM82_11415	COG0318	PFAM AMP-dependent synthetase and ligase
HBM82_11420	COG1309	transcriptional regulator
HBM82_11425	COG1960	acyl-CoA dehydrogenase activity
HBM82_11430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HBM82_11435	COG1024	Enoyl-CoA hydratase
HBM82_11440	COG4770	biotin carboxylase activity
HBM82_11450	COG0583	DNA-binding transcription factor activity
HBM82_11465	COG1960	acyl-CoA dehydrogenase activity
HBM82_11475	COG2814	Major facilitator Superfamily
HBM82_11485	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HBM82_11490	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HBM82_11495	COG2814	Major facilitator Superfamily
HBM82_11500	COG1960	acyl-CoA dehydrogenase activity
HBM82_11505	COG1024	Enoyl-CoA hydratase
HBM82_11510	COG1028	Short-chain dehydrogenase reductase Sdr
HBM82_11515	COG1250	3-hydroxyacyl-CoA dehydrogenase
HBM82_11520	COG0183	Belongs to the thiolase family
HBM82_11530	COG2814	Major facilitator Superfamily
HBM82_11540	COG1024	Enoyl-CoA hydratase
HBM82_11555	COG1960	acyl-CoA dehydrogenase activity
HBM82_11560	COG2814	Major facilitator Superfamily
HBM82_11565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HBM82_11570	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HBM82_11585	COG3842	ATPase activity
HBM82_11590	COG1840	ABC-type Fe3 transport system, periplasmic component
HBM82_11600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HBM82_11605	COG1414	Transcriptional regulator
HBM82_11615	COG0583	DNA-binding transcription factor activity
HBM82_11620	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HBM82_11625	COG1012	belongs to the aldehyde dehydrogenase family
HBM82_11635	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HBM82_11645	COG1012	belongs to the aldehyde dehydrogenase family
HBM82_11650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBM82_11655	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBM82_11660	COG2267	carboxylic ester hydrolase activity
HBM82_11680	COG3038	cytochrome b561
HBM82_11685	COG0753	catalase activity
HBM82_11720	COG2050	protein possibly involved in aromatic compounds catabolism
HBM82_11730	COG3327	negative regulation of DNA-templated transcription, initiation
HBM82_11735	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HBM82_11740	COG0183	Belongs to the thiolase family
HBM82_11745	COG1250	3-hydroxyacyl-CoA dehydrogenase
HBM82_11750	COG1024	Enoyl-CoA hydratase
HBM82_11755	COG1024	Enoyl-CoA hydratase
HBM82_11760	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HBM82_11765	COG2151	metal-sulfur cluster biosynthetic enzyme
HBM82_11770	COG3396	Phenylacetate-CoA oxygenase
HBM82_11775	COG3460	Phenylacetate-CoA oxygenase
HBM82_11780	COG3396	Phenylacetate-CoA oxygenase
HBM82_11785	COG1012	belongs to the aldehyde dehydrogenase family
HBM82_11785	COG2030	dehydratase
HBM82_11790	COG1760	l-serine dehydratase
HBM82_11795	COG0531	amino acid
HBM82_11800	COG1012	belongs to the aldehyde dehydrogenase family
HBM82_11815	COG0446	pyridine nucleotide-disulphide oxidoreductase
HBM82_11825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HBM82_11845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBM82_11855	COG0789	Transcriptional regulator
HBM82_11870	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HBM82_11885	COG2807	transmembrane transport
HBM82_11890	COG0590	tRNA wobble adenosine to inosine editing
HBM82_12005	COG1116	anion transmembrane transporter activity
HBM82_12010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBM82_12020	COG0864	Transcriptional regulator
HBM82_12040	COG2249	NAD(P)H dehydrogenase (quinone) activity
HBM82_12045	COG0439	Biotin carboxylase
HBM82_12060	COG1063	alcohol dehydrogenase
HBM82_12070	COG1309	transcriptional regulator
HBM82_12090	COG0038	chloride channel
HBM82_12095	COG4770	biotin carboxylase activity
HBM82_12115	COG1914	H( )-stimulated, divalent metal cation uptake system
HBM82_12120	COG0583	DNA-binding transcription factor activity
HBM82_12135	COG3209	COG3209 Rhs family protein
HBM82_12140	COG3501	Rhs element vgr protein
HBM82_12170	COG1250	3-hydroxyacyl-CoA dehydrogenase
HBM82_12190	COG2814	Major facilitator Superfamily
HBM82_12200	COG1560	Kdo2-lipid A biosynthetic process
HBM82_12210	COG5006	permease, DMT superfamily
HBM82_12215	COG1522	sequence-specific DNA binding
HBM82_12230	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HBM82_12240	COG4122	O-methyltransferase activity
HBM82_12270	COG1538	Outer membrane efflux protein
HBM82_12280	COG1137	ATPase activity
HBM82_12285	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HBM82_12295	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HBM82_12300	COG0517	IMP dehydrogenase activity
HBM82_12300	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HBM82_12340	COG2814	Major facilitator Superfamily
HBM82_12375	COG1278	Cold shock
HBM82_12380	COG1280	lysine exporter protein (LysE YggA)
HBM82_12415	COG1570	exodeoxyribonuclease VII activity
HBM82_12465	COG0583	DNA-binding transcription factor activity
HBM82_12470	COG4638	Rieske (2fe-2S)
HBM82_12475	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HBM82_12480	COG0633	Ferredoxin
HBM82_12480	COG0543	2 iron, 2 sulfur cluster binding
HBM82_12485	COG1028	Short-chain dehydrogenase reductase Sdr
HBM82_12490	COG3135	benzoate transporter
HBM82_12495	COG2814	Major facilitator Superfamily
HBM82_12510	COG1643	Atp-dependent helicase
HBM82_12515	COG0450	alkyl hydroperoxide reductase
HBM82_12525	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HBM82_12535	COG3634	alkyl hydroperoxide reductase activity
HBM82_12555	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HBM82_12560	COG0625	glutathione transferase activity
HBM82_12570	COG2885	chlorophyll binding
HBM82_12605	COG0542	response to heat
HBM82_12620	COG1765	OsmC-like protein
HBM82_12635	COG0667	Aldo Keto reductase
HBM82_12650	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HBM82_12660	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HBM82_12785	COG3566	protein conserved in bacteria
HBM82_12800	COG3567	Phage-associated protein, HI1409 family
HBM82_12805	COG5410	chromosome segregation
HBM82_12905	COG4197	protein conserved in bacteria, prophage-related
HBM82_12910	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HBM82_12960	COG0527	aspartate kinase activity
HBM82_12970	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HBM82_12980	COG3038	cytochrome b561
HBM82_12985	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HBM82_12990	COG2252	PERMEase
HBM82_13000	COG2072	flavoprotein involved in K transport
HBM82_13015	COG1741	Belongs to the pirin family
HBM82_13020	COG1309	transcriptional regulator
HBM82_13045	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HBM82_13085	COG0446	pyridine nucleotide-disulphide oxidoreductase
HBM82_13085	COG1902	pentaerythritol trinitrate reductase activity
HBM82_13095	COG5001	Diguanylate cyclase
HBM82_13095	COG4251	negative regulation of phosphorylation
HBM82_13095	COG3706	GGDEF domain
HBM82_13095	COG2203	Gaf domain
HBM82_13105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HBM82_13125	COG4172	Belongs to the ABC transporter superfamily
HBM82_13130	COG4239	(ABC) transporter, permease
HBM82_13135	COG4174	ABC transporter (Permease)
HBM82_13145	COG1388	LysM domain
HBM82_13145	COG0741	lytic transglycosylase activity
HBM82_13145	COG0741	lytic transglycosylase activity
HBM82_13145	COG1388	LysM domain
HBM82_13150	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HBM82_13190	COG0583	DNA-binding transcription factor activity
HBM82_13195	COG1279	arginine transmembrane transporter activity
HBM82_13215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HBM82_13220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HBM82_13225	COG0006	proline dipeptidase activity
HBM82_13260	COG2194	sulfuric ester hydrolase activity
HBM82_13305	COG0739	heme binding
HBM82_13630	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HBM82_13660	COG3384	dioxygenase
HBM82_13670	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HBM82_13675	COG2878	Part of a membrane complex involved in electron transport
HBM82_13680	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HBM82_13705	COG0768	penicillin binding
HBM82_13710	COG0742	ribosomal rna small subunit methyltransferase
HBM82_13725	COG0830	nickel cation binding
HBM82_13735	COG0804	urea catabolic process
HBM82_13775	COG1253	flavin adenine dinucleotide binding
HBM82_13780	COG2851	Citrate transporter
HBM82_13835	COG1773	rubredoxin
HBM82_13840	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBM82_13850	COG0583	DNA-binding transcription factor activity
HBM82_13875	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HBM82_13880	COG4181	ATPase activity
HBM82_13925	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HBM82_13945	COG0306	phosphate transporter
HBM82_13955	COG3958	Transketolase
HBM82_13960	COG3959	Transketolase, thiamine diphosphate binding domain
HBM82_13965	COG2271	Major facilitator Superfamily
HBM82_13970	COG1028	Short-chain dehydrogenase reductase Sdr
HBM82_13975	COG0583	DNA-binding transcription factor activity
HBM82_13990	COG2223	nitrite transmembrane transporter activity
HBM82_13995	COG2207	Transcriptional regulator
HBM82_14000	COG2066	Belongs to the glutaminase family
HBM82_14005	COG0242	peptide deformylase activity
HBM82_14010	COG0477	Major facilitator Superfamily
HBM82_14020	COG0028	Belongs to the TPP enzyme family
HBM82_14035	COG1028	Short-chain dehydrogenase reductase Sdr
HBM82_14040	COG2267	carboxylic ester hydrolase activity
HBM82_14050	COG2271	Major facilitator Superfamily
HBM82_14055	COG0446	pyridine nucleotide-disulphide oxidoreductase
HBM82_14065	COG1028	Short-chain dehydrogenase reductase Sdr
HBM82_14085	COG1414	Transcriptional regulator
HBM82_14100	COG1024	Enoyl-CoA hydratase
HBM82_14110	COG1215	transferase activity, transferring glycosyl groups
HBM82_14115	COG1649	PFAM Uncharacterised BCR, COG1649
HBM82_14115	COG0726	polysaccharide deacetylase
HBM82_14125	COG4681	YaeQ
HBM82_14135	COG0523	cobalamin synthesis protein
HBM82_14145	COG1607	acyl-coa hydrolase
HBM82_14155	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBM82_14160	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBM82_14165	COG1309	transcriptional regulator
HBM82_14190	COG2040	homocysteine
HBM82_14195	COG0531	amino acid
HBM82_14250	COG1595	DNA-templated transcription, initiation
HBM82_14260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBM82_14265	COG0477	Major facilitator Superfamily
HBM82_14285	COG0084	hydrolase, TatD family'
HBM82_14320	COG0629	single-stranded DNA binding
HBM82_14375	COG0582	viral genome integration into host DNA
HBM82_14385	COG0405	Gamma-glutamyltransferase
HBM82_14390	COG2814	Major facilitator Superfamily
HBM82_14400	COG2050	protein possibly involved in aromatic compounds catabolism
HBM82_14415	COG1090	epimerase
HBM82_14435	COG0420	3'-5' exonuclease activity
HBM82_14460	COG0735	belongs to the Fur family
HBM82_14465	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HBM82_14485	COG0121	glutamine amidotransferase
HBM82_14500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HBM82_14510	COG0210	DNA helicase
HBM82_14515	COG2885	chlorophyll binding
HBM82_14520	COG0204	Acyl-transferase
HBM82_14535	COG2894	cell division
HBM82_14555	COG1280	lysine exporter protein (LysE YggA)
HBM82_14560	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HBM82_14560	COG1674	ftsk spoiiie
HBM82_14565	COG0492	ferredoxin-NADP+ reductase activity
HBM82_14570	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HBM82_14580	COG0456	acetyltransferase
HBM82_14640	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HBM82_14640	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HBM82_14660	COG1012	belongs to the aldehyde dehydrogenase family
HBM82_14680	COG0473	3-isopropylmalate dehydrogenase activity
HBM82_14685	COG0583	DNA-binding transcription factor activity
HBM82_14705	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HBM82_14730	COG0564	pseudouridine synthase activity
HBM82_14740	COG0358	DNA primase activity
HBM82_14755	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HBM82_14785	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HBM82_14815	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HBM82_14825	COG0352	thiamine-phosphate diphosphorylase activity
HBM82_14825	COG0351	phosphomethylpyrimidine kinase
HBM82_14825	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HBM82_14830	COG1652	LysM domain
HBM82_14855	COG1399	metal-binding, possibly nucleic acid-binding protein
HBM82_14875	COG0009	L-threonylcarbamoyladenylate synthase
HBM82_14880	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HBM82_14885	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HBM82_14900	COG4106	trans-aconitate 2-methyltransferase activity
HBM82_14915	COG2226	methyltransferase
HBM82_14915	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HBM82_14915	COG0596	Alpha beta hydrolase
HBM82_14920	COG1877	trehalose-phosphatase activity
HBM82_14925	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HBM82_14930	COG2223	nitrite transmembrane transporter activity
HBM82_14950	COG1196	nuclear chromosome segregation
HBM82_14960	COG0730	response to heat
HBM82_14975	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HBM82_14985	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HBM82_15035	COG0489	protein tyrosine kinase activity
HBM82_15045	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HBM82_15045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HBM82_15075	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HBM82_15080	COG2081	HI0933 family
HBM82_15090	COG0668	transmembrane transport
HBM82_15110	COG0583	DNA-binding transcription factor activity
HBM82_15130	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HBM82_15135	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HBM82_15165	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HBM82_15200	COG2205	protein histidine kinase activity
HBM82_15205	COG0745	RESPONSE REGULATOR receiver
HBM82_15225	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HBM82_15235	COG2205	protein histidine kinase activity
HBM82_15275	COG3328	transposase activity
HBM82_15315	COG4993	Dehydrogenase
HBM82_15335	COG0384	phenazine biosynthesis protein PhzF
HBM82_15355	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBM82_15370	COG0583	DNA-binding transcription factor activity
HBM82_15390	COG1473	amidohydrolase
HBM82_15400	COG0583	DNA-binding transcription factor activity
HBM82_15415	COG0583	DNA-binding transcription factor activity
HBM82_15420	COG1053	succinate dehydrogenase
HBM82_15430	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HBM82_15435	COG2814	Major facilitator Superfamily
HBM82_15440	COG1960	acyl-CoA dehydrogenase activity
HBM82_15445	COG0583	DNA-binding transcription factor activity
HBM82_15450	COG1063	alcohol dehydrogenase
HBM82_15480	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HBM82_15485	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HBM82_15490	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HBM82_15505	COG3667	copper resistance
HBM82_15510	COG2132	Multicopper oxidase
HBM82_15520	COG0561	phosphatase activity
HBM82_15525	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HBM82_15550	COG1214	PFAM Peptidase M22, glycoprotease
HBM82_15605	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HBM82_15615	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HBM82_15620	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HBM82_15625	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HBM82_15685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HBM82_15695	COG1846	Transcriptional regulator
HBM82_15700	COG1764	response to oxidative stress
HBM82_15750	COG0037	tRNA processing
HBM82_15760	COG0248	Ppx GppA phosphatase
HBM82_15790	COG0072	phenylalanine-tRNA ligase activity
HBM82_15830	COG1238	metal cluster binding
HBM82_15835	COG0625	glutathione transferase activity
HBM82_15850	COG0318	PFAM AMP-dependent synthetase and ligase
HBM82_15855	COG3028	Belongs to the UPF0307 family
HBM82_15860	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBM82_15880	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HBM82_15885	COG0617	tRNA 3'-terminal CCA addition
HBM82_15890	COG1555	photosystem II stabilization
HBM82_15895	COG3956	TIGRFAM MazG family protein
HBM82_15905	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HBM82_15925	COG5002	protein histidine kinase activity
HBM82_15925	COG0784	Response regulator, receiver
HBM82_15925	COG2205	protein histidine kinase activity
HBM82_15930	COG1024	Enoyl-CoA hydratase
HBM82_15935	COG2084	Dehydrogenase
HBM82_15940	COG3622	Belongs to the hyi family
HBM82_15970	COG0697	spore germination
HBM82_15980	COG2814	Major facilitator Superfamily
HBM82_15985	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HBM82_15995	COG0583	DNA-binding transcription factor activity
HBM82_16005	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HBM82_16020	COG0084	hydrolase, TatD family'
HBM82_16035	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HBM82_16065	COG0440	acetolactate synthase activity
HBM82_16070	COG0028	Belongs to the TPP enzyme family
HBM82_16095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBM82_16100	COG0577	efflux transmembrane transporter activity
HBM82_16100	COG1136	(ABC) transporter
HBM82_16105	COG1538	Outer membrane efflux protein
HBM82_16120	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HBM82_16125	COG1162	GTPase activity
HBM82_16135	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HBM82_16155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HBM82_16160	COG1028	Short-chain dehydrogenase reductase Sdr
HBM82_16200	COG2986	histidine ammonia-lyase
HBM82_16215	COG0318	PFAM AMP-dependent synthetase and ligase
HBM82_16225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HBM82_16270	COG1426	Protein conserved in bacteria
HBM82_16305	COG0793	Belongs to the peptidase S41A family
HBM82_16320	COG2267	carboxylic ester hydrolase activity
HBM82_16330	COG1012	belongs to the aldehyde dehydrogenase family
HBM82_16335	COG3265	gluconokinase activity
HBM82_16345	COG0800	Aldolase
HBM82_16360	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HBM82_16365	COG0280	phosphate acetyltransferase
HBM82_16365	COG0857	belongs to the CobB CobQ family
HBM82_16370	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HBM82_16370	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HBM82_16390	COG0740	serine-type endopeptidase activity
HBM82_16400	COG4774	siderophore transport
HBM82_16410	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HBM82_16420	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HBM82_16420	COG2813	Specifically methylates the guanine in position
HBM82_16520	COG0788	formyltetrahydrofolate deformylase activity
HBM82_16545	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HBM82_16545	COG4651	solute:proton antiporter activity
HBM82_16565	COG0724	RNA recognition motif
HBM82_16570	COG0210	DNA helicase
HBM82_16595	COG1733	regulation of RNA biosynthetic process
HBM82_16605	COG2900	Belongs to the SlyX family
HBM82_16615	COG1280	lysine exporter protein (LysE YggA)
HBM82_16620	COG1560	Kdo2-lipid A biosynthetic process
HBM82_16630	COG1301	dicarboxylic acid transport
HBM82_16685	COG0473	3-isopropylmalate dehydrogenase activity
HBM82_16750	COG0583	DNA-binding transcription factor activity
HBM82_16760	COG0625	glutathione transferase activity
HBM82_16765	COG2378	regulation of single-species biofilm formation
HBM82_16770	COG0546	phosphoglycolate phosphatase activity
HBM82_16785	COG1530	ribonuclease E activity
HBM82_16790	COG0318	PFAM AMP-dependent synthetase and ligase
HBM82_16805	COG0583	DNA-binding transcription factor activity
HBM82_16810	COG4221	oxidoreductase activity
HBM82_16815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HBM82_16825	COG0534	Mate efflux family protein
HBM82_16840	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HBM82_16880	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HBM82_16885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBM82_16900	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HBM82_16910	COG0644	oxidoreductase
HBM82_16910	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HBM82_16915	COG0425	Belongs to the sulfur carrier protein TusA family
HBM82_16920	COG4535	Mg2 and Co2 transporter CorC
HBM82_16930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HBM82_16950	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HBM82_16955	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HBM82_16955	COG0475	glutathione-regulated potassium exporter activity
HBM82_16960	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HBM82_16970	COG0484	heat shock protein binding
HBM82_16975	COG0789	Transcriptional regulator
HBM82_16980	COG0598	Magnesium transport protein CorA
HBM82_17000	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HBM82_17005	COG1074	ATP-dependent DNA helicase activity
HBM82_17010	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HBM82_17030	COG2226	methyltransferase
HBM82_17045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HBM82_17050	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HBM82_17065	COG2111	Na H antiporter
HBM82_17065	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HBM82_17070	COG1006	Multisubunit Na H antiporter MnhC subunit
HBM82_17075	COG0651	ATP synthesis coupled electron transport
HBM82_17085	COG2212	antiporter activity
HBM82_17105	COG0195	Participates in both transcription termination and antitermination
HBM82_17155	COG0237	dephospho-CoA kinase activity
HBM82_17165	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HBM82_17180	COG0497	DNA recombination
HBM82_17190	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HBM82_17220	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HBM82_17220	COG2169	Transcriptional regulator
HBM82_17225	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HBM82_17290	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HBM82_17305	COG0326	Molecular chaperone. Has ATPase activity
HBM82_17320	COG2056	Na+-H+ antiporter family
HBM82_17325	COG0596	Alpha beta hydrolase
HBM82_17420	COG0546	phosphoglycolate phosphatase activity
HBM82_17425	COG1716	ATPase activity
HBM82_17470	COG0181	hydroxymethylbilane synthase activity
HBM82_17480	COG3275	phosphorelay sensor kinase activity
HBM82_17500	COG1538	Outer membrane efflux protein
HBM82_17505	COG0697	spore germination
HBM82_17530	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HBM82_17535	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HBM82_17540	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HBM82_17545	COG0772	Belongs to the SEDS family
HBM82_17570	COG4974	Belongs to the 'phage' integrase family
HBM82_17575	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HBM82_17585	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HBM82_17595	COG2197	response regulator
HBM82_17610	COG0793	Belongs to the peptidase S41A family
HBM82_17615	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HBM82_17620	COG0795	lipopolysaccharide-transporting ATPase activity
HBM82_17660	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HBM82_17660	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HBM82_17670	COG0004	ammonium transporteR
HBM82_17675	COG0347	Belongs to the P(II) protein family
HBM82_17685	COG0606	chelatase, subunit chli
HBM82_17760	COG1061	Type III restriction enzyme res subunit
HBM82_17775	COG0659	secondary active sulfate transmembrane transporter activity
HBM82_17780	COG0589	response to stress
HBM82_17810	COG0606	chelatase, subunit chli
HBM82_17825	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBM82_17840	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HBM82_17855	COG0318	PFAM AMP-dependent synthetase and ligase
HBM82_17865	COG0477	Major facilitator Superfamily
HBM82_17870	COG2860	membrane
HBM82_17880	COG1253	flavin adenine dinucleotide binding
HBM82_17900	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HBM82_17935	COG0655	NAD(P)H dehydrogenase (quinone) activity
HBM82_17945	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HBM82_17980	COG1309	transcriptional regulator
HBM82_18015	COG0758	DNA mediated transformation
HBM82_18025	COG0697	spore germination
HBM82_18030	COG1309	transcriptional regulator
HBM82_18045	COG0386	Belongs to the glutathione peroxidase family
HBM82_18110	COG1121	(ABC) transporter
HBM82_18115	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HBM82_18120	COG1280	lysine exporter protein (LysE YggA)
HBM82_18125	COG2837	iron assimilation
HBM82_18135	COG0281	malic enzyme
HBM82_18180	COG0519	Catalyzes the synthesis of GMP from XMP
HBM82_18180	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HBM82_18185	COG4399	Belongs to the UPF0754 family
HBM82_18190	COG2259	Doxx family
HBM82_18195	COG0586	Pfam SNARE associated Golgi protein
HBM82_18210	COG1192	Involved in chromosome partitioning
HBM82_18220	COG0271	Belongs to the BolA IbaG family
HBM82_18240	COG2267	carboxylic ester hydrolase activity
HBM82_18260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HBM82_18260	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HBM82_18260	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HBM82_18260	COG3321	synthase
HBM82_18265	COG1960	acyl-CoA dehydrogenase activity
HBM82_18275	COG2197	response regulator
HBM82_18285	COG3916	Acyl-homoserine-lactone synthase
HBM82_18290	COG0477	Major facilitator Superfamily
HBM82_18295	COG1024	Enoyl-CoA hydratase
HBM82_18300	COG1024	Enoyl-CoA hydratase
HBM82_18305	COG1960	acyl-CoA dehydrogenase activity
HBM82_18310	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HBM82_18330	COG1113	amino acid transport
HBM82_18335	COG1113	amino acid transport
HBM82_18340	COG0251	oxidation-reduction process
HBM82_18380	COG0564	pseudouridine synthase activity
HBM82_18440	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HBM82_18455	COG1802	Transcriptional regulator
HBM82_18465	COG1448	Aminotransferase
HBM82_18470	COG0277	FAD linked oxidase domain protein
HBM82_18480	COG2186	Transcriptional regulator
HBM82_18490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HBM82_18495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HBM82_18510	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HBM82_18515	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HBM82_18540	COG0438	transferase activity, transferring glycosyl groups
HBM82_18570	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HBM82_18600	COG0728	peptidoglycan biosynthetic process
HBM82_18605	COG3023	N-Acetylmuramoyl-L-alanine amidase
HBM82_18660	COG0546	phosphoglycolate phosphatase activity
HBM82_18665	COG1028	Short-chain dehydrogenase reductase Sdr
HBM82_18685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBM82_18690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBM82_18695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBM82_18700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBM82_18705	COG1116	anion transmembrane transporter activity
HBM82_18710	COG1309	transcriptional regulator
HBM82_18715	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HBM82_18725	COG0196	riboflavin kinase activity
HBM82_18730	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HBM82_18740	COG1047	Peptidyl-prolyl cis-trans
HBM82_18780	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HBM82_18835	COG2951	lytic endotransglycosylase activity
HBM82_18840	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HBM82_18855	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HBM82_18865	COG0671	phosphoesterase, PA-phosphatase related
HBM82_18870	COG0861	Integral membrane protein TerC family
HBM82_18880	COG0754	glutathionylspermidine amidase activity
HBM82_18890	COG0402	S-adenosylhomocysteine deaminase activity
HBM82_18905	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HBM82_18910	COG1230	cation diffusion facilitator family transporter
HBM82_18925	COG0706	membrane insertase activity
