locus-tag	class	description
CUC60_000135	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CUC60_000190	COG2194	sulfuric ester hydrolase activity
CUC60_000560	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CUC60_000585	COG3384	dioxygenase
CUC60_000595	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CUC60_000600	COG2878	Part of a membrane complex involved in electron transport
CUC60_000605	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CUC60_000630	COG0768	penicillin binding
CUC60_000635	COG0742	ribosomal rna small subunit methyltransferase
CUC60_000650	COG0830	nickel cation binding
CUC60_000700	COG1253	flavin adenine dinucleotide binding
CUC60_000710	COG2851	Citrate transporter
CUC60_000760	COG1773	rubredoxin
CUC60_000765	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CUC60_000775	COG0583	DNA-binding transcription factor activity
CUC60_000810	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CUC60_000815	COG4181	ATPase activity
CUC60_000890	COG3958	Transketolase
CUC60_000895	COG3959	Transketolase, thiamine diphosphate binding domain
CUC60_000900	COG2271	Major facilitator Superfamily
CUC60_000905	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_000910	COG0583	DNA-binding transcription factor activity
CUC60_000930	COG2223	nitrite transmembrane transporter activity
CUC60_000935	COG2207	Transcriptional regulator
CUC60_000940	COG2066	Belongs to the glutaminase family
CUC60_000945	COG0242	peptide deformylase activity
CUC60_000950	COG0477	Major facilitator Superfamily
CUC60_000960	COG0028	Belongs to the TPP enzyme family
CUC60_000975	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_000980	COG2267	carboxylic ester hydrolase activity
CUC60_000990	COG2271	Major facilitator Superfamily
CUC60_000995	COG0446	pyridine nucleotide-disulphide oxidoreductase
CUC60_001005	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_001025	COG1414	Transcriptional regulator
CUC60_001040	COG1024	Enoyl-CoA hydratase
CUC60_001050	COG1215	transferase activity, transferring glycosyl groups
CUC60_001065	COG4681	YaeQ
CUC60_001075	COG0523	cobalamin synthesis protein
CUC60_001085	COG1607	acyl-coa hydrolase
CUC60_001095	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CUC60_001100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CUC60_001105	COG1309	transcriptional regulator
CUC60_001130	COG2040	homocysteine
CUC60_001135	COG0531	amino acid
CUC60_001190	COG1595	DNA-templated transcription, initiation
CUC60_001200	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CUC60_001205	COG0477	Major facilitator Superfamily
CUC60_001225	COG0084	hydrolase, TatD family'
CUC60_001325	COG0592	DNA-directed DNA polymerase activity
CUC60_001365	COG2026	Addiction module toxin, RelE StbE family
CUC60_001515	COG3755	Protein conserved in bacteria
CUC60_001560	COG1484	DNA-dependent DNA replication
CUC60_001650	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CUC60_001715	COG0405	Gamma-glutamyltransferase
CUC60_001720	COG2814	Major facilitator Superfamily
CUC60_001730	COG2050	protein possibly involved in aromatic compounds catabolism
CUC60_001745	COG1090	epimerase
CUC60_001770	COG0420	3'-5' exonuclease activity
CUC60_001795	COG0735	belongs to the Fur family
CUC60_001800	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CUC60_001825	COG0121	glutamine amidotransferase
CUC60_001840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CUC60_001850	COG0210	DNA helicase
CUC60_001855	COG2885	chlorophyll binding
CUC60_001860	COG0204	Acyl-transferase
CUC60_001875	COG2894	cell division
CUC60_001895	COG1280	lysine exporter protein (LysE YggA)
CUC60_001900	COG1674	ftsk spoiiie
CUC60_001900	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CUC60_001905	COG0492	ferredoxin-NADP+ reductase activity
CUC60_001910	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CUC60_001920	COG0456	acetyltransferase
CUC60_001980	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CUC60_001980	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CUC60_002000	COG1012	belongs to the aldehyde dehydrogenase family
CUC60_002020	COG0473	3-isopropylmalate dehydrogenase activity
CUC60_002025	COG0583	DNA-binding transcription factor activity
CUC60_002045	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CUC60_002070	COG0564	pseudouridine synthase activity
CUC60_002080	COG0358	DNA primase activity
CUC60_002095	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CUC60_002125	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CUC60_002155	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CUC60_002165	COG0352	thiamine-phosphate diphosphorylase activity
CUC60_002165	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CUC60_002165	COG0351	phosphomethylpyrimidine kinase
CUC60_002170	COG1652	LysM domain
CUC60_002195	COG1399	metal-binding, possibly nucleic acid-binding protein
CUC60_002200	COG3101	peptidyl-lysine hydroxylation
CUC60_002205	COG0009	L-threonylcarbamoyladenylate synthase
CUC60_002210	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CUC60_002215	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CUC60_002230	COG4106	trans-aconitate 2-methyltransferase activity
CUC60_002245	COG0596	Alpha beta hydrolase
CUC60_002245	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CUC60_002245	COG2226	methyltransferase
CUC60_002250	COG1877	trehalose-phosphatase activity
CUC60_002255	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CUC60_002260	COG2223	nitrite transmembrane transporter activity
CUC60_002280	COG1196	nuclear chromosome segregation
CUC60_002290	COG0730	response to heat
CUC60_002305	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CUC60_002315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CUC60_002375	COG0489	protein tyrosine kinase activity
CUC60_002385	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CUC60_002385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CUC60_002415	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CUC60_002420	COG2081	HI0933 family
CUC60_002430	COG0668	transmembrane transport
CUC60_002450	COG0583	DNA-binding transcription factor activity
CUC60_002470	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CUC60_002475	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CUC60_002505	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CUC60_002540	COG2205	protein histidine kinase activity
CUC60_002545	COG0745	RESPONSE REGULATOR receiver
CUC60_002565	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CUC60_002645	COG4993	Dehydrogenase
CUC60_002665	COG0384	phenazine biosynthesis protein PhzF
CUC60_002695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CUC60_002700	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CUC60_002710	COG0583	DNA-binding transcription factor activity
CUC60_002730	COG1473	amidohydrolase
CUC60_002740	COG0583	DNA-binding transcription factor activity
CUC60_002760	COG0583	DNA-binding transcription factor activity
CUC60_002775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CUC60_002780	COG2814	Major facilitator Superfamily
CUC60_002785	COG1960	acyl-CoA dehydrogenase activity
CUC60_002790	COG0583	DNA-binding transcription factor activity
CUC60_002795	COG1063	alcohol dehydrogenase
CUC60_002825	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CUC60_002830	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CUC60_002835	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CUC60_002860	COG3667	copper resistance
CUC60_002865	COG2132	Multicopper oxidase
CUC60_002875	COG0561	phosphatase activity
CUC60_002880	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CUC60_002905	COG1214	PFAM Peptidase M22, glycoprotease
CUC60_002955	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CUC60_002965	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CUC60_002970	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CUC60_002975	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CUC60_003035	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CUC60_003045	COG1846	Transcriptional regulator
CUC60_003050	COG1764	response to oxidative stress
CUC60_003090	COG0037	tRNA processing
CUC60_003100	COG0248	Ppx GppA phosphatase
CUC60_003155	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CUC60_003170	COG1238	metal cluster binding
CUC60_003175	COG0625	glutathione transferase activity
CUC60_003195	COG0318	PFAM AMP-dependent synthetase and ligase
CUC60_003200	COG3028	Belongs to the UPF0307 family
CUC60_003205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUC60_003225	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CUC60_003230	COG0617	tRNA 3'-terminal CCA addition
CUC60_003235	COG1555	photosystem II stabilization
CUC60_003240	COG3956	TIGRFAM MazG family protein
CUC60_003250	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CUC60_003270	COG0784	Response regulator, receiver
CUC60_003270	COG2205	protein histidine kinase activity
CUC60_003270	COG5002	protein histidine kinase activity
CUC60_003275	COG1024	Enoyl-CoA hydratase
CUC60_003280	COG2084	Dehydrogenase
CUC60_003285	COG3622	Belongs to the hyi family
CUC60_003300	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CUC60_003305	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CUC60_003310	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CUC60_003315	COG0697	spore germination
CUC60_003325	COG2814	Major facilitator Superfamily
CUC60_003330	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CUC60_003340	COG0583	DNA-binding transcription factor activity
CUC60_003350	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CUC60_003365	COG0084	hydrolase, TatD family'
CUC60_003380	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CUC60_003415	COG0440	acetolactate synthase activity
CUC60_003420	COG0028	Belongs to the TPP enzyme family
CUC60_003445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUC60_003450	COG1136	(ABC) transporter
CUC60_003450	COG0577	efflux transmembrane transporter activity
CUC60_003455	COG1538	Outer membrane efflux protein
CUC60_003470	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CUC60_003475	COG1162	GTPase activity
CUC60_003485	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CUC60_003505	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CUC60_003510	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_003550	COG2986	histidine ammonia-lyase
CUC60_003575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CUC60_003580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CUC60_003620	COG1426	Protein conserved in bacteria
CUC60_003655	COG0793	Belongs to the peptidase S41A family
CUC60_003670	COG2267	carboxylic ester hydrolase activity
CUC60_003680	COG1012	belongs to the aldehyde dehydrogenase family
CUC60_003685	COG3265	gluconokinase activity
CUC60_003705	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CUC60_003710	COG0857	belongs to the CobB CobQ family
CUC60_003710	COG0280	phosphate acetyltransferase
CUC60_003715	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CUC60_003715	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CUC60_003735	COG0740	serine-type endopeptidase activity
CUC60_003745	COG4774	siderophore transport
CUC60_003755	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CUC60_003765	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CUC60_003765	COG2813	Specifically methylates the guanine in position
CUC60_003865	COG0788	formyltetrahydrofolate deformylase activity
CUC60_003880	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CUC60_003885	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CUC60_003890	COG4651	solute:proton antiporter activity
CUC60_003890	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CUC60_003910	COG0724	RNA recognition motif
CUC60_003915	COG0210	DNA helicase
CUC60_003940	COG1733	regulation of RNA biosynthetic process
CUC60_003960	COG1280	lysine exporter protein (LysE YggA)
CUC60_003965	COG1560	Kdo2-lipid A biosynthetic process
CUC60_003975	COG1301	dicarboxylic acid transport
CUC60_004030	COG0473	3-isopropylmalate dehydrogenase activity
CUC60_004095	COG0583	DNA-binding transcription factor activity
CUC60_004105	COG0625	glutathione transferase activity
CUC60_004110	COG2378	regulation of single-species biofilm formation
CUC60_004115	COG0546	phosphoglycolate phosphatase activity
CUC60_004130	COG1530	ribonuclease E activity
CUC60_004150	COG0583	DNA-binding transcription factor activity
CUC60_004160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CUC60_004170	COG0534	Mate efflux family protein
CUC60_004185	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CUC60_004225	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CUC60_004230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CUC60_004245	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CUC60_004255	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CUC60_004255	COG0644	oxidoreductase
CUC60_004260	COG0425	Belongs to the sulfur carrier protein TusA family
CUC60_004265	COG4535	Mg2 and Co2 transporter CorC
CUC60_004275	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CUC60_004295	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CUC60_004300	COG0475	glutathione-regulated potassium exporter activity
CUC60_004300	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CUC60_004305	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CUC60_004315	COG0484	heat shock protein binding
CUC60_004320	COG0789	Transcriptional regulator
CUC60_004325	COG0598	Magnesium transport protein CorA
CUC60_004345	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CUC60_004350	COG1074	ATP-dependent DNA helicase activity
CUC60_004355	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CUC60_004375	COG2226	methyltransferase
CUC60_004390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CUC60_004395	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CUC60_004410	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CUC60_004410	COG2111	Na H antiporter
CUC60_004415	COG1006	Multisubunit Na H antiporter MnhC subunit
CUC60_004420	COG0651	ATP synthesis coupled electron transport
CUC60_004430	COG2212	antiporter activity
CUC60_004450	COG0195	Participates in both transcription termination and antitermination
CUC60_004500	COG0237	dephospho-CoA kinase activity
CUC60_004510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CUC60_004525	COG0497	DNA recombination
CUC60_004535	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CUC60_004565	COG2169	Transcriptional regulator
CUC60_004565	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CUC60_004570	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CUC60_004640	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CUC60_004655	COG0326	Molecular chaperone. Has ATPase activity
CUC60_004670	COG2056	Na+-H+ antiporter family
CUC60_004675	COG0596	Alpha beta hydrolase
CUC60_004770	COG0546	phosphoglycolate phosphatase activity
CUC60_004775	COG1716	ATPase activity
CUC60_004820	COG0181	hydroxymethylbilane synthase activity
CUC60_004830	COG3275	phosphorelay sensor kinase activity
CUC60_004850	COG1538	Outer membrane efflux protein
CUC60_004855	COG0697	spore germination
CUC60_004880	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CUC60_004885	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CUC60_004890	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CUC60_004895	COG0772	Belongs to the SEDS family
CUC60_004920	COG4974	Belongs to the 'phage' integrase family
CUC60_004925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CUC60_004935	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CUC60_004945	COG2197	response regulator
CUC60_004960	COG0793	Belongs to the peptidase S41A family
CUC60_005010	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CUC60_005010	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CUC60_005020	COG0004	ammonium transporteR
CUC60_005025	COG0347	Belongs to the P(II) protein family
CUC60_005035	COG0606	chelatase, subunit chli
CUC60_005070	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CUC60_005090	COG1192	Involved in chromosome partitioning
CUC60_005275	COG0482	sulfurtransferase activity
CUC60_005310	COG3316	Transposase and inactivated derivatives
CUC60_005375	COG1061	Type III restriction enzyme res subunit
CUC60_005395	COG0589	response to stress
CUC60_005440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CUC60_005490	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CUC60_005525	COG0589	response to stress
CUC60_005555	COG0606	chelatase, subunit chli
CUC60_005560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CUC60_005570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CUC60_005585	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CUC60_005600	COG0318	PFAM AMP-dependent synthetase and ligase
CUC60_005610	COG0477	Major facilitator Superfamily
CUC60_005615	COG2860	membrane
CUC60_005620	COG3012	SEC-C Motif Domain Protein
CUC60_005625	COG1253	flavin adenine dinucleotide binding
CUC60_005635	COG2814	Major facilitator Superfamily
CUC60_005645	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CUC60_005680	COG0655	NAD(P)H dehydrogenase (quinone) activity
CUC60_005690	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CUC60_005725	COG1309	transcriptional regulator
CUC60_005760	COG0758	DNA mediated transformation
CUC60_005770	COG0697	spore germination
CUC60_005775	COG1309	transcriptional regulator
CUC60_005790	COG0386	Belongs to the glutathione peroxidase family
CUC60_005860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CUC60_005865	COG1280	lysine exporter protein (LysE YggA)
CUC60_005870	COG2837	iron assimilation
CUC60_005875	COG0281	malic enzyme
CUC60_005920	COG0519	Catalyzes the synthesis of GMP from XMP
CUC60_005920	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CUC60_005930	COG2259	Doxx family
CUC60_005935	COG0586	Pfam SNARE associated Golgi protein
CUC60_005950	COG1192	Involved in chromosome partitioning
CUC60_005960	COG0271	Belongs to the BolA IbaG family
CUC60_005980	COG2267	carboxylic ester hydrolase activity
CUC60_006000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CUC60_006000	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CUC60_006000	COG3321	synthase
CUC60_006000	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CUC60_006005	COG1960	acyl-CoA dehydrogenase activity
CUC60_006015	COG2197	response regulator
CUC60_006025	COG3916	Acyl-homoserine-lactone synthase
CUC60_006035	COG1024	Enoyl-CoA hydratase
CUC60_006040	COG1024	Enoyl-CoA hydratase
CUC60_006045	COG1960	acyl-CoA dehydrogenase activity
CUC60_006050	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CUC60_006070	COG1113	amino acid transport
CUC60_006075	COG1113	amino acid transport
CUC60_006080	COG0251	oxidation-reduction process
CUC60_006095	COG1522	sequence-specific DNA binding
CUC60_006120	COG0564	pseudouridine synthase activity
CUC60_006180	COG2801	Transposase and inactivated derivatives
CUC60_006220	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CUC60_006235	COG1802	Transcriptional regulator
CUC60_006245	COG1448	Aminotransferase
CUC60_006250	COG0277	FAD linked oxidase domain protein
CUC60_006260	COG2186	Transcriptional regulator
CUC60_006270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CUC60_006275	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CUC60_006290	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CUC60_006305	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CUC60_006320	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CUC60_006355	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_006365	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_006370	COG1083	cytidylyl-transferase
CUC60_006375	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CUC60_006385	COG2089	acid synthase
CUC60_006390	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CUC60_006395	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CUC60_006405	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CUC60_006435	COG0728	peptidoglycan biosynthetic process
CUC60_006440	COG3023	N-Acetylmuramoyl-L-alanine amidase
CUC60_006495	COG0546	phosphoglycolate phosphatase activity
CUC60_006500	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_006520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CUC60_006525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CUC60_006530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CUC60_006535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CUC60_006540	COG1116	anion transmembrane transporter activity
CUC60_006545	COG1309	transcriptional regulator
CUC60_006550	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CUC60_006560	COG0196	riboflavin kinase activity
CUC60_006565	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CUC60_006575	COG1047	Peptidyl-prolyl cis-trans
CUC60_006620	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CUC60_006625	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CUC60_006630	COG0596	Alpha beta hydrolase
CUC60_006655	COG0488	(ABC) transporter
CUC60_006660	COG0586	Pfam SNARE associated Golgi protein
CUC60_006670	COG0187	DNA topoisomerase II activity
CUC60_006680	COG0592	DNA-directed DNA polymerase activity
CUC60_006690	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CUC60_006705	COG0706	membrane insertase activity
CUC60_006720	COG1230	cation diffusion facilitator family transporter
CUC60_006725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CUC60_006750	COG0754	glutathionylspermidine amidase activity
CUC60_006760	COG0861	Integral membrane protein TerC family
CUC60_006765	COG0671	phosphoesterase, PA-phosphatase related
CUC60_006775	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CUC60_006795	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CUC60_006800	COG2951	lytic endotransglycosylase activity
CUC60_006855	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CUC60_006895	COG0733	neurotransmitter:sodium symporter activity
CUC60_006930	COG0583	DNA-binding transcription factor activity
CUC60_006935	COG2233	PERMEase
CUC60_006950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUC60_006985	COG2814	Major facilitator Superfamily
CUC60_006990	COG0656	L-ascorbic acid biosynthetic process
CUC60_006995	COG0583	DNA-binding transcription factor activity
CUC60_007010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CUC60_007015	COG1064	alcohol dehydrogenase
CUC60_007020	COG2818	Glycosylase
CUC60_007035	COG1194	a g-specific adenine glycosylase
CUC60_007055	COG2983	Belongs to the UPF0260 family
CUC60_007060	COG2133	pyrroloquinoline quinone binding
CUC60_007065	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CUC60_007070	COG2116	formate transmembrane transporter activity
CUC60_007090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CUC60_007095	COG1335	isochorismatase
CUC60_007100	COG0385	Bile acid
CUC60_007105	COG0534	Mate efflux family protein
CUC60_007110	COG1683	Conserved Protein
CUC60_007130	COG0625	glutathione transferase activity
CUC60_007140	COG1113	amino acid transport
CUC60_007150	COG0523	cobalamin synthesis protein
CUC60_007190	COG0010	Belongs to the arginase family
CUC60_007205	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CUC60_007225	COG0745	RESPONSE REGULATOR receiver
CUC60_007225	COG2205	protein histidine kinase activity
CUC60_007225	COG4191	Histidine kinase
CUC60_007260	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CUC60_007270	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CUC60_007275	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CUC60_007365	COG0534	Mate efflux family protein
CUC60_007370	COG0436	Aminotransferase
CUC60_007375	COG2733	membrane
CUC60_007390	COG2918	glutathione biosynthetic process
CUC60_007450	COG3150	esterase
CUC60_007460	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_007465	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CUC60_007475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CUC60_007485	COG2233	PERMEase
CUC60_007490	COG2351	hydroxyisourate hydrolase activity
CUC60_007525	COG3706	GGDEF domain
CUC60_007540	COG1393	Belongs to the ArsC family
CUC60_007545	COG0708	Exodeoxyribonuclease III
CUC60_007565	COG0189	ligase activity
CUC60_007585	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CUC60_007595	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CUC60_007610	COG4942	peptidase
CUC60_007620	COG0508	dehydrogenase complex catalyzes the overall conversion of
CUC60_007630	COG2119	membrane
CUC60_007635	COG4774	siderophore transport
CUC60_007640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CUC60_007640	COG0426	domain, Protein
CUC60_007665	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CUC60_007685	COG1902	pentaerythritol trinitrate reductase activity
CUC60_007695	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CUC60_007700	COG0668	transmembrane transport
CUC60_007710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CUC60_007715	COG1335	isochorismatase
CUC60_007720	COG1522	sequence-specific DNA binding
CUC60_007725	COG3328	transposase activity
CUC60_007750	COG2198	Histidine kinase
CUC60_007750	COG0784	Response regulator, receiver
CUC60_007750	COG2205	protein histidine kinase activity
CUC60_007755	COG3162	membrane
CUC60_007760	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CUC60_007770	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CUC60_007780	COG3706	GGDEF domain
CUC60_007790	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CUC60_007795	COG1309	transcriptional regulator
CUC60_007815	COG0351	phosphomethylpyrimidine kinase
CUC60_007815	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CUC60_007815	COG0352	thiamine-phosphate diphosphorylase activity
CUC60_007825	COG2814	Major facilitator Superfamily
CUC60_007840	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CUC60_007850	COG1113	amino acid transport
CUC60_007860	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CUC60_007865	COG1012	belongs to the aldehyde dehydrogenase family
CUC60_007875	COG1335	isochorismatase
CUC60_007905	COG2814	Major facilitator Superfamily
CUC60_007910	COG0583	DNA-binding transcription factor activity
CUC60_007930	COG0667	Aldo Keto reductase
CUC60_007965	COG1733	regulation of RNA biosynthetic process
CUC60_007975	COG2249	NAD(P)H dehydrogenase (quinone) activity
CUC60_008040	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CUC60_008055	COG2329	Antibiotic biosynthesis monooxygenase
CUC60_008085	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CUC60_008115	COG0427	acetyl-CoA hydrolase
CUC60_008130	COG0745	RESPONSE REGULATOR receiver
CUC60_008140	COG0659	secondary active sulfate transmembrane transporter activity
CUC60_008145	COG4221	oxidoreductase activity
CUC60_008155	COG0488	(ABC) transporter
CUC60_008240	COG0833	amino acid
CUC60_008285	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CUC60_008290	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CUC60_008305	COG2226	methyltransferase
CUC60_008355	COG0070	glutamate synthase
CUC60_008355	COG0067	glutamate synthase
CUC60_008355	COG0069	glutamate synthase activity
CUC60_008360	COG0493	'glutamate synthase
CUC60_008370	COG1704	LemA family
CUC60_008375	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CUC60_008395	COG3307	-O-antigen
CUC60_008420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CUC60_008435	COG0194	GDP metabolic process
CUC60_008485	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CUC60_008505	COG5380	lipid catabolic process
CUC60_008510	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CUC60_008535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CUC60_008540	COG0277	FAD linked oxidase domain protein
CUC60_008550	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CUC60_008555	COG2249	NAD(P)H dehydrogenase (quinone) activity
CUC60_008570	COG1289	transmembrane transporter activity
CUC60_008580	COG0628	permease
CUC60_008585	COG1192	Involved in chromosome partitioning
CUC60_008615	COG0833	amino acid
CUC60_008620	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CUC60_008635	COG1012	belongs to the aldehyde dehydrogenase family
CUC60_008680	COG0583	DNA-binding transcription factor activity
CUC60_008725	COG0517	IMP dehydrogenase activity
CUC60_008730	COG1983	PspC domain protein
CUC60_008740	COG1960	acyl-CoA dehydrogenase activity
CUC60_008760	COG0408	coproporphyrinogen oxidase activity
CUC60_008780	COG0513	Belongs to the DEAD box helicase family
CUC60_008790	COG1127	ABC transporter
CUC60_008795	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CUC60_008805	COG2854	intermembrane phospholipid transfer
CUC60_008815	COG0598	Magnesium transport protein CorA
CUC60_008825	COG0494	nUDIX hydrolase
CUC60_008830	COG1040	competence protein
CUC60_008835	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CUC60_008855	COG1946	Acyl-CoA thioesterase
CUC60_008860	COG1301	dicarboxylic acid transport
CUC60_008880	COG1959	2 iron, 2 sulfur cluster binding
CUC60_008885	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CUC60_008885	COG1017	nitric oxide dioxygenase activity
CUC60_008890	COG0433	COG0433 Predicted ATPase
CUC60_008895	COG0626	cystathionine gamma-synthase activity
CUC60_009015	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CUC60_009025	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CUC60_009050	COG1960	acyl-CoA dehydrogenase activity
CUC60_009055	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CUC60_009085	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CUC60_009090	COG0339	signal peptide processing
CUC60_009095	COG0557	exoribonuclease II activity
CUC60_009140	COG0179	Fumarylacetoacetate (FAA) hydrolase
CUC60_009145	COG2169	Transcriptional regulator
CUC60_009150	COG0697	spore germination
CUC60_009155	COG1295	ribonuclease BN
CUC60_009190	COG1702	phosphate starvation-inducible protein PhoH
CUC60_009200	COG0741	lytic transglycosylase activity
CUC60_009200	COG0739	heme binding
CUC60_009200	COG1196	nuclear chromosome segregation
CUC60_009230	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CUC60_009235	COG1183	phosphatidylcholine synthase activity
CUC60_009280	COG1960	acyl-CoA dehydrogenase activity
CUC60_009285	COG1309	transcriptional regulator
CUC60_009300	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CUC60_009305	COG1960	acyl-CoA dehydrogenase activity
CUC60_009325	COG2969	positive regulation of protein catabolic process
CUC60_009335	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CUC60_009350	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CUC60_009355	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CUC60_009375	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CUC60_009385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CUC60_009390	COG1408	metallophosphoesterase
CUC60_009400	COG2199	diguanylate cyclase activity
CUC60_009445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CUC60_009445	COG3453	Protein conserved in bacteria
CUC60_009460	COG1607	acyl-coa hydrolase
CUC60_009490	COG2350	Protein conserved in bacteria
CUC60_009500	COG0613	PHP domain protein
CUC60_009505	COG3781	membrane
CUC60_009515	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CUC60_009520	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CUC60_009530	COG1862	Preprotein translocase
CUC60_009560	COG2205	protein histidine kinase activity
CUC60_009565	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CUC60_009585	COG0726	polysaccharide deacetylase
CUC60_009590	COG0463	Glycosyl transferase, family 2
CUC60_009595	COG0438	transferase activity, transferring glycosyl groups
CUC60_009660	COG0625	glutathione transferase activity
CUC60_009665	COG0583	DNA-binding transcription factor activity
CUC60_009670	COG1960	acyl-CoA dehydrogenase activity
CUC60_009675	COG1960	acyl-CoA dehydrogenase activity
CUC60_009685	COG2205	protein histidine kinase activity
CUC60_009690	COG0745	RESPONSE REGULATOR receiver
CUC60_009695	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CUC60_009715	COG2096	Adenosyltransferase
CUC60_009730	COG0133	tryptophan synthase activity
CUC60_009765	COG0285	dihydrofolate synthase activity
CUC60_009785	COG0450	alkyl hydroperoxide reductase
CUC60_009800	COG0477	Major facilitator Superfamily
CUC60_009805	COG1272	protein, Hemolysin III
CUC60_009835	COG0183	Belongs to the thiolase family
CUC60_009840	COG2207	Transcriptional regulator
CUC60_009860	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CUC60_009880	COG0183	Belongs to the thiolase family
CUC60_009890	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CUC60_009890	COG2885	chlorophyll binding
CUC60_009900	COG1690	Belongs to the RtcB family
CUC60_009905	COG0833	amino acid
CUC60_009915	COG2233	PERMEase
CUC60_009945	COG2094	Belongs to the DNA glycosylase MPG family
CUC60_009950	COG4772	TonB-dependent receptor
CUC60_009965	COG1902	pentaerythritol trinitrate reductase activity
CUC60_009980	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CUC60_009985	COG0354	folic acid binding
CUC60_009995	COG3189	MarR family transcriptional regulator
CUC60_010000	COG2824	Alkylphosphonate utilization operon protein PhnA
CUC60_010005	COG3422	double-strand break repair
CUC60_010045	COG0840	transmembrane signaling receptor activity
CUC60_010065	COG5510	response to toxic substance
CUC60_010075	COG2832	Protein of unknown function (DUF454)
CUC60_010080	COG1376	ErfK ybiS ycfS ynhG family protein
CUC60_010130	COG1289	transmembrane transporter activity
CUC60_010135	COG2814	Major facilitator Superfamily
CUC60_010155	COG1115	amino acid carrier protein
CUC60_010165	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CUC60_010170	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CUC60_010200	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CUC60_010210	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CUC60_010215	COG1077	Cell shape determining protein MreB Mrl
CUC60_010220	COG1792	Involved in formation and maintenance of cell shape
CUC60_010225	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CUC60_010230	COG0424	maF-like protein
CUC60_010235	COG1530	ribonuclease E activity
CUC60_010245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CUC60_010265	COG2249	NAD(P)H dehydrogenase (quinone) activity
CUC60_010290	COG2207	Transcriptional regulator
CUC60_010310	COG1113	amino acid transport
CUC60_010315	COG2828	Protein conserved in bacteria
CUC60_010320	COG0142	geranyltranstransferase activity
CUC60_010325	COG2315	Protein conserved in bacteria
CUC60_010340	COG1752	Esterase of the alpha-beta hydrolase superfamily
CUC60_010365	COG2194	sulfuric ester hydrolase activity
CUC60_010370	COG0745	RESPONSE REGULATOR receiver
CUC60_010375	COG0642	Histidine kinase
CUC60_010385	COG0004	ammonium transporteR
CUC60_010395	COG0583	DNA-binding transcription factor activity
CUC60_010415	COG0525	valine-tRNA ligase activity
CUC60_010425	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_010435	COG0393	Putative heavy-metal-binding
CUC60_010440	COG0393	Putative heavy-metal-binding
CUC60_010445	COG1538	Outer membrane efflux protein
CUC60_010455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUC60_010460	COG0671	phosphoesterase, PA-phosphatase related
CUC60_010490	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CUC60_010505	COG1648	precorrin-2 dehydrogenase activity
CUC60_010505	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CUC60_010510	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CUC60_010515	COG1733	regulation of RNA biosynthetic process
CUC60_010525	COG0531	amino acid
CUC60_010540	COG0321	lipoyl(octanoyl) transferase activity
CUC60_010545	COG2921	Belongs to the UPF0250 family
CUC60_010585	COG2009	succinate dehydrogenase
CUC60_010590	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CUC60_010595	COG1053	succinate dehydrogenase
CUC60_010600	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CUC60_010625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CUC60_010645	COG2354	Protein conserved in bacteria
CUC60_010650	COG2321	neutral zinc metallopeptidase
CUC60_010700	COG0589	response to stress
CUC60_010720	COG0505	Belongs to the CarA family
CUC60_010745	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CUC60_010750	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CUC60_010800	COG0477	Major facilitator Superfamily
CUC60_010805	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CUC60_010825	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CUC60_010855	COG0584	glycerophosphoryl diester phosphodiesterase
CUC60_010875	COG0741	lytic transglycosylase activity
CUC60_010900	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CUC60_010915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CUC60_010935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUC60_010965	COG4584	PFAM Integrase catalytic
CUC60_010965	COG2390	Transcriptional regulator
CUC60_010970	COG1484	DNA-dependent DNA replication
CUC60_011000	COG0778	Nitroreductase
CUC60_011015	COG1929	Belongs to the glycerate kinase type-1 family
CUC60_011020	COG0243	molybdopterin cofactor binding
CUC60_011025	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CUC60_011030	COG3339	Conserved Protein
CUC60_011040	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CUC60_011055	COG1113	amino acid transport
CUC60_011075	COG1280	lysine exporter protein (LysE YggA)
CUC60_011080	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CUC60_011110	COG0463	Glycosyl transferase, family 2
CUC60_011130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUC60_011160	COG4591	ABC-type transport system involved in lipoprotein release permease component
CUC60_011165	COG1136	(ABC) transporter
CUC60_011170	COG0658	competence protein
CUC60_011170	COG2333	competence protein COMEC
CUC60_011180	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CUC60_011180	COG0616	signal peptide processing
CUC60_011185	COG0596	Alpha beta hydrolase
CUC60_011190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CUC60_011200	COG0628	permease
CUC60_011235	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CUC60_011255	COG0823	Involved in the tonB-independent uptake of proteins
CUC60_011275	COG0824	Thioesterase
CUC60_011280	COG1473	amidohydrolase
CUC60_011300	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CUC60_011300	COG0047	phosphoribosylformylglycinamidine synthase activity
CUC60_011305	COG2814	Major facilitator Superfamily
CUC60_011310	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CUC60_011315	COG1024	Enoyl-CoA hydratase
CUC60_011320	COG1056	cytidyltransferase-related domain
CUC60_011320	COG1051	belongs to the nudix hydrolase family
CUC60_011330	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CUC60_011345	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CUC60_011360	COG4625	pathogenesis
CUC60_011365	COG0583	DNA-binding transcription factor activity
CUC60_011370	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CUC60_011375	COG4208	sulfate ABC transporter
CUC60_011380	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CUC60_011390	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CUC60_011395	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CUC60_011400	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CUC60_011420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CUC60_011435	COG0681	Belongs to the peptidase S26 family
CUC60_011450	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CUC60_011460	COG1381	Involved in DNA repair and RecF pathway recombination
CUC60_011465	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CUC60_011475	COG4221	oxidoreductase activity
CUC60_011525	COG0556	nucleotide-excision repair
CUC60_011610	COG1215	transferase activity, transferring glycosyl groups
CUC60_011625	COG0415	Belongs to the DNA photolyase family
CUC60_011635	COG1252	NADH dehydrogenase
CUC60_011655	COG1187	pseudouridine synthase activity
CUC60_011685	COG0583	DNA-binding transcription factor activity
CUC60_011725	COG0352	thiamine-phosphate diphosphorylase activity
CUC60_011760	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CUC60_011775	COG1309	transcriptional regulator
CUC60_011785	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CUC60_011800	COG1522	sequence-specific DNA binding
CUC60_011805	COG3961	Belongs to the TPP enzyme family
CUC60_011810	COG1113	amino acid transport
CUC60_011815	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CUC60_011820	COG0573	inorganic phosphate transmembrane transporter activity
CUC60_011830	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CUC60_011835	COG0616	signal peptide processing
CUC60_011870	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CUC60_011875	COG1686	Belongs to the peptidase S11 family
CUC60_011900	COG0583	DNA-binding transcription factor activity
CUC60_011905	COG1067	ATP-dependent peptidase activity
CUC60_011950	COG1966	Carbon starvation protein
CUC60_011955	COG2879	small protein
CUC60_011990	COG2508	Transcriptional regulator
CUC60_011990	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CUC60_012010	COG1113	amino acid transport
CUC60_012015	COG0583	DNA-binding transcription factor activity
CUC60_012020	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CUC60_012025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CUC60_012040	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CUC60_012045	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CUC60_012045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CUC60_012080	COG2814	Major facilitator Superfamily
CUC60_012085	COG4948	Mandelate Racemase Muconate Lactonizing
CUC60_012095	COG1309	transcriptional regulator
CUC60_012115	COG1741	Belongs to the pirin family
CUC60_012125	COG2964	Protein conserved in bacteria
CUC60_012140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CUC60_012145	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CUC60_012150	COG4605	iron ion homeostasis
CUC60_012155	COG4604	ABC transporter, ATP-binding protein
CUC60_012160	COG4607	ABC-type enterochelin transport system periplasmic component
CUC60_012175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CUC60_012180	COG1021	2,3-dihydroxybenzoate-AMP ligase
CUC60_012185	COG1535	isochorismatase
CUC60_012185	COG3433	isochorismatase activity
CUC60_012200	COG1132	(ABC) transporter
CUC60_012210	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CUC60_012220	COG1169	isochorismate synthase
CUC60_012235	COG3739	integral membrane protein
CUC60_012305	COG0512	Glutamine amidotransferase of anthranilate synthase
CUC60_012480	COG5410	chromosome segregation
CUC60_012635	COG0582	viral genome integration into host DNA
CUC60_012645	COG3104	oligopeptide transport
CUC60_012695	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CUC60_012705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CUC60_012725	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CUC60_012730	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CUC60_012735	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CUC60_012750	COG1960	acyl-CoA dehydrogenase activity
CUC60_012755	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CUC60_012760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CUC60_012770	COG2223	nitrite transmembrane transporter activity
CUC60_012780	COG0024	Methionine aminopeptidase
CUC60_012785	COG0052	Belongs to the universal ribosomal protein uS2 family
CUC60_012800	COG2207	Transcriptional regulator
CUC60_012825	COG2951	lytic endotransglycosylase activity
CUC60_012830	COG0772	Belongs to the SEDS family
CUC60_012845	COG0842	Transport permease protein
CUC60_012850	COG1131	(ABC) transporter
CUC60_012885	COG1538	Outer membrane efflux protein
CUC60_012895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUC60_012910	COG4215	(ABC) transporter
CUC60_012915	COG4160	amino acid transport
CUC60_012930	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CUC60_012940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CUC60_012955	COG1720	tRNA m6t6A37 methyltransferase activity
CUC60_012975	COG0745	RESPONSE REGULATOR receiver
CUC60_012980	COG0642	Histidine kinase
CUC60_012990	COG0494	nUDIX hydrolase
CUC60_013005	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CUC60_013010	COG3139	Protein of unknown function (DUF1315)
CUC60_013015	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CUC60_013025	COG1301	dicarboxylic acid transport
CUC60_013030	COG1960	acyl-CoA dehydrogenase activity
CUC60_013035	COG2819	hydrolase of the alpha beta superfamily
CUC60_013045	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CUC60_013055	COG2195	Cleaves the N-terminal amino acid of tripeptides
CUC60_013060	COG1234	tRNA 3'-trailer cleavage
CUC60_013090	COG2363	Small membrane protein
CUC60_013110	COG0513	Belongs to the DEAD box helicase family
CUC60_013120	COG0778	Nitroreductase
CUC60_013150	COG1286	toxin biosynthetic process
CUC60_013175	COG4783	chaperone-mediated protein folding
CUC60_013180	COG1610	YqeY-like protein
CUC60_013185	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CUC60_013280	COG3111	PFAM Bacterial OB fold (BOF) protein
CUC60_013305	COG3243	poly(R)-hydroxyalkanoic acid synthase
CUC60_013310	COG0786	glutamate:sodium symporter activity
CUC60_013320	COG2186	Transcriptional regulator
CUC60_013370	COG0477	Major facilitator Superfamily
CUC60_013400	COG2985	domain, Protein
CUC60_013410	COG2995	paraquat-inducible protein a
CUC60_013415	COG3008	intermembrane lipid transfer
CUC60_013415	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CUC60_013425	COG1794	racemase activity, acting on amino acids and derivatives
CUC60_013445	COG3316	Transposase and inactivated derivatives
CUC60_013465	COG3316	Transposase and inactivated derivatives
CUC60_013520	COG1113	amino acid transport
CUC60_013530	COG0531	amino acid
CUC60_013550	COG1012	belongs to the aldehyde dehydrogenase family
CUC60_013570	COG1113	amino acid transport
CUC60_013600	COG0300	oxidoreductase activity
CUC60_013610	COG1309	transcriptional regulator
CUC60_013615	COG1741	Belongs to the pirin family
CUC60_013630	COG2072	flavoprotein involved in K transport
CUC60_013640	COG2252	PERMEase
CUC60_013645	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CUC60_013650	COG3038	cytochrome b561
CUC60_013660	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CUC60_013680	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CUC60_013690	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CUC60_013705	COG0667	Aldo Keto reductase
CUC60_013720	COG1765	OsmC-like protein
CUC60_013770	COG2885	chlorophyll binding
CUC60_013780	COG0625	glutathione transferase activity
CUC60_013785	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CUC60_013805	COG3634	alkyl hydroperoxide reductase activity
CUC60_013820	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CUC60_013830	COG0450	alkyl hydroperoxide reductase
CUC60_013835	COG1643	Atp-dependent helicase
CUC60_013855	COG3135	benzoate transporter
CUC60_013860	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_013865	COG0543	2 iron, 2 sulfur cluster binding
CUC60_013865	COG0633	Ferredoxin
CUC60_013870	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CUC60_013875	COG4638	Rieske (2fe-2S)
CUC60_013880	COG0583	DNA-binding transcription factor activity
CUC60_013935	COG1570	exodeoxyribonuclease VII activity
CUC60_013970	COG1280	lysine exporter protein (LysE YggA)
CUC60_013975	COG1278	Cold shock
CUC60_014015	COG2814	Major facilitator Superfamily
CUC60_014020	COG1733	regulation of RNA biosynthetic process
CUC60_014055	COG0517	IMP dehydrogenase activity
CUC60_014055	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CUC60_014060	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CUC60_014070	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CUC60_014075	COG1137	ATPase activity
CUC60_014080	COG1538	Outer membrane efflux protein
CUC60_014120	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CUC60_014135	COG1522	sequence-specific DNA binding
CUC60_014140	COG5006	permease, DMT superfamily
CUC60_014150	COG1560	Kdo2-lipid A biosynthetic process
CUC60_014165	COG2814	Major facilitator Superfamily
CUC60_014185	COG1250	3-hydroxyacyl-CoA dehydrogenase
CUC60_014220	COG3501	Rhs element vgr protein
CUC60_014225	COG3209	COG3209 Rhs family protein
CUC60_014240	COG0583	DNA-binding transcription factor activity
CUC60_014245	COG1914	H( )-stimulated, divalent metal cation uptake system
CUC60_014265	COG4770	biotin carboxylase activity
CUC60_014270	COG0038	chloride channel
CUC60_014290	COG1309	transcriptional regulator
CUC60_014300	COG1063	alcohol dehydrogenase
CUC60_014315	COG0439	Biotin carboxylase
CUC60_014320	COG2249	NAD(P)H dehydrogenase (quinone) activity
CUC60_014340	COG0864	Transcriptional regulator
CUC60_014350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CUC60_014355	COG1116	anion transmembrane transporter activity
CUC60_014425	COG2885	chlorophyll binding
CUC60_014425	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CUC60_014465	COG0583	DNA-binding transcription factor activity
CUC60_014475	COG0590	tRNA wobble adenosine to inosine editing
CUC60_014480	COG2807	transmembrane transport
CUC60_014495	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CUC60_014510	COG0789	Transcriptional regulator
CUC60_014525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CUC60_014545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CUC60_014555	COG0446	pyridine nucleotide-disulphide oxidoreductase
CUC60_014570	COG1012	belongs to the aldehyde dehydrogenase family
CUC60_014575	COG0531	amino acid
CUC60_014580	COG1760	l-serine dehydratase
CUC60_014585	COG1012	belongs to the aldehyde dehydrogenase family
CUC60_014585	COG2030	dehydratase
CUC60_014590	COG3396	Phenylacetate-CoA oxygenase
CUC60_014595	COG3460	Phenylacetate-CoA oxygenase
CUC60_014600	COG3396	Phenylacetate-CoA oxygenase
CUC60_014605	COG2151	metal-sulfur cluster biosynthetic enzyme
CUC60_014610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CUC60_014615	COG1024	Enoyl-CoA hydratase
CUC60_014620	COG1024	Enoyl-CoA hydratase
CUC60_014625	COG1250	3-hydroxyacyl-CoA dehydrogenase
CUC60_014630	COG0183	Belongs to the thiolase family
CUC60_014635	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CUC60_014640	COG3327	negative regulation of DNA-templated transcription, initiation
CUC60_014650	COG2050	protein possibly involved in aromatic compounds catabolism
CUC60_014690	COG0753	catalase activity
CUC60_014695	COG3038	cytochrome b561
CUC60_014715	COG2267	carboxylic ester hydrolase activity
CUC60_014720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CUC60_014725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CUC60_014730	COG1012	belongs to the aldehyde dehydrogenase family
CUC60_014740	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CUC60_014750	COG1012	belongs to the aldehyde dehydrogenase family
CUC60_014755	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CUC60_014760	COG0583	DNA-binding transcription factor activity
CUC60_014770	COG1414	Transcriptional regulator
CUC60_014775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CUC60_014785	COG1840	ABC-type Fe3 transport system, periplasmic component
CUC60_014790	COG3842	ATPase activity
CUC60_014805	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CUC60_014810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CUC60_014815	COG2814	Major facilitator Superfamily
CUC60_014820	COG1960	acyl-CoA dehydrogenase activity
CUC60_014835	COG1024	Enoyl-CoA hydratase
CUC60_014845	COG2814	Major facilitator Superfamily
CUC60_014855	COG0183	Belongs to the thiolase family
CUC60_014860	COG1250	3-hydroxyacyl-CoA dehydrogenase
CUC60_014865	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_014870	COG1024	Enoyl-CoA hydratase
CUC60_014875	COG1960	acyl-CoA dehydrogenase activity
CUC60_014880	COG2814	Major facilitator Superfamily
CUC60_014885	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CUC60_014890	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CUC60_014900	COG2814	Major facilitator Superfamily
CUC60_014910	COG1960	acyl-CoA dehydrogenase activity
CUC60_014925	COG0583	DNA-binding transcription factor activity
CUC60_014940	COG1024	Enoyl-CoA hydratase
CUC60_014945	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CUC60_014950	COG1960	acyl-CoA dehydrogenase activity
CUC60_014955	COG1309	transcriptional regulator
CUC60_014960	COG0318	PFAM AMP-dependent synthetase and ligase
CUC60_014980	COG0583	DNA-binding transcription factor activity
CUC60_015025	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_015045	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CUC60_015065	COG2205	protein histidine kinase activity
CUC60_015065	COG0784	Response regulator, receiver
CUC60_015085	COG0765	amino acid transport
CUC60_015090	COG0765	amino acid transport
CUC60_015095	COG1126	abc transporter atp-binding protein
CUC60_015100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CUC60_015105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CUC60_015120	COG1280	lysine exporter protein (LysE YggA)
CUC60_015125	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CUC60_015130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CUC60_015135	COG1045	serine acetyltransferase
CUC60_015150	COG0583	DNA-binding transcription factor activity
CUC60_015155	COG0625	glutathione transferase activity
CUC60_015160	COG0625	glutathione transferase activity
CUC60_015165	COG0583	DNA-binding transcription factor activity
CUC60_015175	COG1346	cytolysis
CUC60_015195	COG2814	Major facilitator Superfamily
CUC60_015205	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CUC60_015210	COG3052	prosthetic group binding
CUC60_015230	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CUC60_015250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CUC60_015260	COG1294	oxidase, subunit
CUC60_015265	COG1271	oxidase subunit
CUC60_015290	COG0477	Major facilitator Superfamily
CUC60_015300	COG4521	taurine ABC transporter
CUC60_015305	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CUC60_015310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CUC60_015315	COG2175	clavaminate synthase activity
CUC60_015325	COG1953	Uracil, thiamine, allantoin
CUC60_015335	COG0583	DNA-binding transcription factor activity
CUC60_015345	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CUC60_015360	COG0640	Transcriptional regulator
CUC60_015365	COG0798	PFAM Bile acid sodium symporter
CUC60_015370	COG0583	DNA-binding transcription factor activity
CUC60_015385	COG3634	alkyl hydroperoxide reductase activity
CUC60_015425	COG0436	Aminotransferase
CUC60_015435	COG0386	Belongs to the glutathione peroxidase family
CUC60_015475	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CUC60_015500	COG0012	GTP binding
CUC60_015505	COG2011	ABC-type metal ion transport system permease component
CUC60_015510	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CUC60_015520	COG1464	Belongs to the NlpA lipoprotein family
CUC60_015550	COG0765	amino acid transport
CUC60_015555	COG0765	amino acid transport
CUC60_015560	COG1126	abc transporter atp-binding protein
CUC60_015570	COG1522	sequence-specific DNA binding
CUC60_015585	COG1309	transcriptional regulator
CUC60_015605	COG0583	DNA-binding transcription factor activity
CUC60_015615	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CUC60_015625	COG0697	spore germination
CUC60_015655	COG3121	Chaperone
CUC60_015660	COG3539	Fimbrial protein
CUC60_015685	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CUC60_015685	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CUC60_015730	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CUC60_015740	COG2353	YceI-like domain
CUC60_015750	COG3698	Phosphodiester glycosidase
CUC60_015765	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CUC60_015780	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CUC60_015785	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CUC60_015805	COG1132	(ABC) transporter
CUC60_015810	COG3122	Protein conserved in bacteria
CUC60_015815	COG3619	membrane
CUC60_015825	COG0640	Transcriptional regulator
CUC60_015835	COG2850	peptidyl-arginine hydroxylation
CUC60_015840	COG0424	maF-like protein
CUC60_015860	COG0191	fructose-bisphosphate aldolase activity
CUC60_015865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CUC60_015880	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CUC60_015890	COG1192	Involved in chromosome partitioning
CUC60_015895	COG1475	DNA binding
CUC60_015900	COG0811	peptide transport
CUC60_015910	COG1132	(ABC) transporter
CUC60_015915	COG1663	tetraacyldisaccharide 4'-kinase activity
CUC60_015935	COG0084	hydrolase, TatD family'
CUC60_015950	COG2165	general secretion pathway protein
CUC60_015980	COG0590	tRNA wobble adenosine to inosine editing
CUC60_016000	COG0776	regulation of translation
CUC60_016030	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CUC60_016325	COG1196	nuclear chromosome segregation
CUC60_016325	COG0739	heme binding
CUC60_016325	COG0741	lytic transglycosylase activity
CUC60_016405	COG0006	proline dipeptidase activity
CUC60_016410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CUC60_016415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CUC60_016435	COG1279	arginine transmembrane transporter activity
CUC60_016440	COG0583	DNA-binding transcription factor activity
CUC60_016480	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CUC60_016485	COG0741	lytic transglycosylase activity
CUC60_016485	COG1388	LysM domain
CUC60_016485	COG1388	LysM domain
CUC60_016485	COG0741	lytic transglycosylase activity
CUC60_016495	COG4174	ABC transporter (Permease)
CUC60_016500	COG4239	(ABC) transporter, permease
CUC60_016505	COG4172	Belongs to the ABC transporter superfamily
CUC60_016535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CUC60_016560	COG1902	pentaerythritol trinitrate reductase activity
CUC60_016560	COG0446	pyridine nucleotide-disulphide oxidoreductase
CUC60_016575	COG4269	membrane
CUC60_016595	COG3501	Rhs element vgr protein
CUC60_016605	COG3316	Transposase and inactivated derivatives
CUC60_016620	COG3316	Transposase and inactivated derivatives
CUC60_016675	COG0482	sulfurtransferase activity
CUC60_016710	COG3316	Transposase and inactivated derivatives
CUC60_016730	COG1301	dicarboxylic acid transport
CUC60_016740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CUC60_016745	COG2011	ABC-type metal ion transport system permease component
CUC60_016750	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CUC60_016755	COG1464	Belongs to the NlpA lipoprotein family
CUC60_016760	COG0151	Belongs to the GarS family
CUC60_016765	COG0138	bifunctional purine biosynthesis protein purh
CUC60_016770	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CUC60_016810	COG1305	Transglutaminase-like
CUC60_016820	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CUC60_016825	COG0305	Participates in initiation and elongation during chromosome replication
CUC60_016850	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CUC60_016860	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CUC60_016865	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CUC60_016890	COG1649	PFAM Uncharacterised BCR, COG1649
CUC60_016890	COG0726	polysaccharide deacetylase
CUC60_016895	COG1215	transferase activity, transferring glycosyl groups
CUC60_016900	COG3658	cytochrome
CUC60_016910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CUC60_016930	COG0583	DNA-binding transcription factor activity
CUC60_016950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CUC60_016955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CUC60_016970	COG1960	acyl-CoA dehydrogenase activity
CUC60_016975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CUC60_016980	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CUC60_017005	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CUC60_017010	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CUC60_017020	COG2205	protein histidine kinase activity
CUC60_017025	COG0745	RESPONSE REGULATOR receiver
CUC60_017030	COG0174	glutamine synthetase
CUC60_017050	COG0729	surface antigen
CUC60_017080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CUC60_017085	COG2814	Major facilitator Superfamily
CUC60_017100	COG0583	DNA-binding transcription factor activity
CUC60_017115	COG1187	pseudouridine synthase activity
CUC60_017135	COG0802	atpase or kinase
CUC60_017140	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CUC60_017150	COG1923	regulation of RNA biosynthetic process
CUC60_017155	COG0697	spore germination
CUC60_017170	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CUC60_017185	COG0519	Catalyzes the synthesis of GMP from XMP
CUC60_017185	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CUC60_017190	COG4302	ethanolamine ammonia-lyase activity
CUC60_017200	COG0531	amino acid
CUC60_017220	COG1454	alcohol dehydrogenase
CUC60_017225	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CUC60_017235	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CUC60_017255	COG0308	aminopeptidase N
CUC60_017265	COG4221	oxidoreductase activity
CUC60_017275	COG1605	Chorismate mutase
CUC60_017295	COG1309	transcriptional regulator
CUC60_017305	COG0668	transmembrane transport
CUC60_017340	COG4773	Receptor
CUC60_017360	COG0488	(ABC) transporter
CUC60_017365	COG0589	response to stress
CUC60_017380	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CUC60_017390	COG3135	benzoate transporter
CUC60_017395	COG1522	sequence-specific DNA binding
CUC60_017410	COG0583	DNA-binding transcription factor activity
CUC60_017420	COG0183	Belongs to the thiolase family
CUC60_017450	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CUC60_017460	COG0824	Thioesterase
CUC60_017465	COG1454	alcohol dehydrogenase
CUC60_017495	COG0069	glutamate synthase activity
CUC60_017605	COG0305	Participates in initiation and elongation during chromosome replication
CUC60_017665	COG5410	chromosome segregation
CUC60_017790	COG0739	heme binding
CUC60_017855	COG2194	sulfuric ester hydrolase activity
CUC60_017860	COG2814	Major facilitator Superfamily
CUC60_017875	COG0511	ligase activity, forming carbon-carbon bonds
CUC60_017895	COG1116	anion transmembrane transporter activity
CUC60_017895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CUC60_017900	COG0745	RESPONSE REGULATOR receiver
CUC60_017910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CUC60_017910	COG2146	nitrite reductase [NAD(P)H] activity
CUC60_017915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CUC60_017920	COG0243	molybdopterin cofactor binding
CUC60_017930	COG0243	molybdopterin cofactor binding
CUC60_017935	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CUC60_017950	COG0521	Mo-molybdopterin cofactor biosynthetic process
CUC60_017950	COG0315	cyclic pyranopterin monophosphate synthase activity
CUC60_017955	COG0303	'Molybdopterin
CUC60_017965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CUC60_017970	COG0697	spore germination
CUC60_017990	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CUC60_017995	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CUC60_018055	COG2204	response regulator
CUC60_018060	COG3852	Histidine kinase
CUC60_018085	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CUC60_018090	COG0575	Belongs to the CDS family
CUC60_018125	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CUC60_018140	COG2137	regulation of response to DNA damage stimulus
CUC60_018150	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CUC60_018155	COG1011	Hydrolase
CUC60_018180	COG1522	sequence-specific DNA binding
CUC60_018190	COG1113	amino acid transport
CUC60_018205	COG0659	secondary active sulfate transmembrane transporter activity
CUC60_018210	COG2135	peptidase activity
CUC60_018245	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CUC60_018245	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CUC60_018245	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CUC60_018250	COG1105	Belongs to the carbohydrate kinase PfkB family
CUC60_018255	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CUC60_018255	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUC60_018285	COG0024	Methionine aminopeptidase
CUC60_018290	COG0583	DNA-binding transcription factor activity
CUC60_018300	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CUC60_018305	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CUC60_018310	COG0517	IMP dehydrogenase activity
CUC60_018310	COG0516	GMP reductase activity
CUC60_018335	COG0552	protein localization to endoplasmic reticulum
CUC60_018345	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CUC60_018360	COG4890	Cyd operon protein YbgT
CUC60_018365	COG1294	oxidase, subunit
CUC60_018385	COG1585	Membrane protein implicated in regulation of membrane protease activity
CUC60_018395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CUC60_018400	COG4774	siderophore transport
CUC60_018415	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CUC60_018420	COG0569	domain protein
CUC60_018425	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CUC60_018455	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CUC60_018460	COG0542	response to heat
CUC60_018470	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CUC60_018485	COG1902	pentaerythritol trinitrate reductase activity
CUC60_018485	COG0446	pyridine nucleotide-disulphide oxidoreductase
CUC60_018530	COG2323	membrane
CUC60_018535	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CUC60_018545	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CUC60_018550	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CUC60_018555	COG0183	Belongs to the thiolase family
CUC60_018560	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CUC60_018565	COG0596	Alpha beta hydrolase
CUC60_018570	COG2271	Major facilitator Superfamily
CUC60_018575	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CUC60_018585	COG3485	protocatechuate 3,4-dioxygenase
CUC60_018590	COG0710	3-dehydroquinate dehydratase activity
CUC60_018600	COG3659	wide pore channel activity
CUC60_018605	COG4993	Dehydrogenase
CUC60_018615	COG2391	methyltransferase activity
CUC60_018635	COG0583	DNA-binding transcription factor activity
CUC60_018640	COG1960	acyl-CoA dehydrogenase activity
CUC60_018665	COG2814	Major facilitator Superfamily
CUC60_018675	COG0154	amidase activity
CUC60_018705	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_018715	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CUC60_018725	COG3733	amine oxidase
CUC60_018735	COG1012	belongs to the aldehyde dehydrogenase family
CUC60_018745	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CUC60_018750	COG0183	Belongs to the thiolase family
CUC60_018755	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CUC60_018760	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CUC60_018770	COG4829	muconolactone delta-isomerase
CUC60_018780	COG0583	DNA-binding transcription factor activity
CUC60_018790	COG2186	Transcriptional regulator
CUC60_018810	COG1012	belongs to the aldehyde dehydrogenase family
CUC60_018830	COG1960	acyl-CoA dehydrogenase activity
CUC60_018835	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_018840	COG3829	transcription factor binding
CUC60_018850	COG3162	membrane
CUC60_018865	COG1012	belongs to the aldehyde dehydrogenase family
CUC60_018880	COG0753	catalase activity
CUC60_018905	COG1846	Transcriptional regulator
CUC60_018910	COG1902	pentaerythritol trinitrate reductase activity
CUC60_018910	COG0446	pyridine nucleotide-disulphide oxidoreductase
CUC60_018920	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CUC60_018950	COG1309	transcriptional regulator
CUC60_018960	COG1335	isochorismatase
CUC60_018975	COG0475	glutathione-regulated potassium exporter activity
CUC60_018975	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CUC60_018985	COG1473	amidohydrolase
CUC60_019000	COG2831	hemolysin activation secretion protein
CUC60_019005	COG3210	domain, Protein
CUC60_019050	COG0583	DNA-binding transcription factor activity
CUC60_019075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CUC60_019080	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CUC60_019100	COG1566	PFAM secretion protein HlyD family protein
CUC60_019115	COG1012	belongs to the aldehyde dehydrogenase family
CUC60_019120	COG0129	dihydroxy-acid dehydratase activity
CUC60_019130	COG0583	DNA-binding transcription factor activity
CUC60_019135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CUC60_019145	COG2084	Dehydrogenase
CUC60_019150	COG2207	Transcriptional regulator
CUC60_019165	COG1064	alcohol dehydrogenase
CUC60_019180	COG1120	ATPase activity
CUC60_019200	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CUC60_019320	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CUC60_019375	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_019390	COG2207	Transcriptional regulator
CUC60_019400	COG2205	protein histidine kinase activity
CUC60_019405	COG0745	RESPONSE REGULATOR receiver
CUC60_019410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUC60_019415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CUC60_019420	COG1538	Outer membrane efflux protein
CUC60_019430	COG2072	flavoprotein involved in K transport
CUC60_019450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CUC60_019470	COG3539	Fimbrial protein
CUC60_019500	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CUC60_019510	COG0753	catalase activity
CUC60_019525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CUC60_019590	COG1535	isochorismatase
CUC60_019590	COG3433	isochorismatase activity
CUC60_019600	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CUC60_019605	COG4149	molybdate abc transporter
CUC60_019610	COG0725	ABC transporter, periplasmic molybdate-binding protein
CUC60_019620	COG4638	Rieske (2fe-2S)
CUC60_019625	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CUC60_019630	COG0543	2 iron, 2 sulfur cluster binding
CUC60_019630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CUC60_019645	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CUC60_019655	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_019660	COG0412	Dienelactone hydrolase
CUC60_019670	COG2207	Transcriptional regulator
CUC60_019680	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_019685	COG2610	gluconate transmembrane transporter activity
CUC60_019695	COG0583	DNA-binding transcription factor activity
CUC60_019705	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CUC60_019710	COG2031	fatty acid transporter
CUC60_019715	COG0183	Belongs to the thiolase family
CUC60_019720	COG0583	DNA-binding transcription factor activity
CUC60_019725	COG0583	DNA-binding transcription factor activity
CUC60_019740	COG1027	Aspartate ammonia-lyase
CUC60_019750	COG0477	Major facilitator Superfamily
CUC60_019770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CUC60_019775	COG4521	taurine ABC transporter
CUC60_019800	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CUC60_019805	COG1733	regulation of RNA biosynthetic process
CUC60_019810	COG3708	Transcriptional regulator
CUC60_019810	COG2207	Transcriptional regulator
CUC60_019825	COG0730	response to heat
CUC60_019835	COG3453	Protein conserved in bacteria
CUC60_019835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CUC60_019845	COG3781	membrane
CUC60_019850	COG1063	alcohol dehydrogenase
CUC60_019860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CUC60_019865	COG0508	dehydrogenase complex catalyzes the overall conversion of
CUC60_019870	COG0022	dehydrogenase e1 component
CUC60_019875	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CUC60_019895	COG3706	GGDEF domain
CUC60_019910	COG0133	tryptophan synthase activity
CUC60_019920	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CUC60_019955	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CUC60_019980	COG2226	methyltransferase
CUC60_020035	COG0842	Transport permease protein
CUC60_020040	COG0842	Transport permease protein
CUC60_020045	COG1131	(ABC) transporter
CUC60_020060	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CUC60_020065	COG4773	Receptor
CUC60_020085	COG0730	response to heat
CUC60_020090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CUC60_020110	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CUC60_020170	COG4264	IucA IucC family
CUC60_020175	COG4264	IucA IucC family
CUC60_020195	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CUC60_020210	COG1960	acyl-CoA dehydrogenase activity
CUC60_020220	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CUC60_020225	COG2207	Transcriptional regulator
CUC60_020230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CUC60_020235	COG0776	regulation of translation
CUC60_020260	COG0822	iron-sulfur transferase activity
CUC60_020265	COG0316	Belongs to the HesB IscA family
CUC60_020315	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CUC60_020320	COG0702	epimerase
CUC60_020355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CUC60_020415	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CUC60_020485	COG0739	heme binding
CUC60_020485	COG1196	nuclear chromosome segregation
CUC60_020485	COG0741	lytic transglycosylase activity
CUC60_020700	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CUC60_020790	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CUC60_020855	COG4683	PFAM Phage derived protein Gp49-like (DUF891)